1. Characteristic features of microvascular responses of healthy humans to simulated emotional stress
- Author
-
M. A. Orlova, Oleg S. Glazachev, and S. Ia. Klassina
- Subjects
medicine.medical_specialty ,Physiology ,business.industry ,Blood flow ,Human physiology ,Emotional stress ,Anatomy ,Laser Doppler velocimetry ,Vascular architecture ,Microcirculation ,Physiology (medical) ,Internal medicine ,Cardiology ,medicine ,Respiratory system ,business ,Shunt (electrical) - Abstract
Characteristic features of microvascular responses of healthy humans to simulated emotional stress (ES) were studied using computer-aided laser Doppler flowmetry. It was shown that, in ES, responses of individual regions of the microvasculature are relatively autonomous and different. In the nail bed, where the arteriolar and the arteriolovenular shunt tone depends on the neurogenic sympathoadrenal regulation, the responses are more pronounced than in the lower arm microvessels. The rearrangements of the nail bed and lower arm microvasculature in response to a simulated situation of ES are different, which is likely to be determined by both their different vascular architecture and other factors (the pressure gradient, metabolic requirements of tissues, etc.). It was established that the ES level determines an increase in the contributions of the neurogenic, myogenic, respiratory, and cardiac components to the modulation of the intensity of microcirculation, increasing the shunt value and the blood flow in microvessels.
- Published
- 2007