65 results on '"Süreyya Soyupak"'
Search Results
2. A rare cause of granulomatous hepatitis: Tularemia
- Author
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Emine Kocabaş, Özlem Özgür Gündeşlioğlu, Merve Kılıç Çil, Ümmühan Çay, Figen Doran, and Süreyya Soyupak
- Subjects
Tularemia ,Granulomatous hepatitis ,Child ,Infectious and parasitic diseases ,RC109-216 ,Public aspects of medicine ,RA1-1270 - Abstract
Tularemia is a zoonotic infection caused by Francisella tularensis. Tularemia has several clinical form in humans, including ulceroglandular, pneumonic, oropharyngeal, oculoglandular, and systemic (typhoidal). Tularemia may develop granulomatous and suppurative lesions, especially in the affected regional lymph nodes and various organs. Patients with hepatic involvement typically have elevated transaminase levels, hepatomegaly and rarely jaundice. Histologically, there are typically suppurative microabscesses with occasional surrounding macrophages. Rarely, hepatic granuloma can develop due to tularemia. We present a case of an 8 year-old male residing in a rural village in Turkey, who came to our hospital after having intermittent fever for four months and right upper abdominal pain for two months. Liver had a nodular appearance in liver imaging and liver biopsy were consistent with granulomatous hepatitis. The microagglutination test was positive for tularemia in the patient who was investigated for granulomatous hepatitis etiology. Symptoms and signs improved with tularemia treatment. We present a rare case of hepatic involvement of tularemia in a child. Clinicians should be suspicious of and evaluate for typhoidal tularemia in patients who present with prolonged fever and non-specific systemic symptoms, potentially with associated abdominal pain.
- Published
- 2020
- Full Text
- View/download PDF
3. İki yenidoğan bebekte pnömomediyastinumun kendiliğinden düzelmesi
- Author
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Hacer Yapıcıoğlu Yıldızdaş, Önder ÖZDEN, Hilmi Serdar İSKİT, Gülseren BİLEN YURDAKUL, Mustafa AKÇALI, Ferda ÖZLÜ, Süreyya SOYUPAK, Mehmet SATAR, and Nejat NARLI
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pneumomediastinum ,diagnosis ,newborn ,pnömomediasten ,tanısal ,bebek ,yenidoğan ,Medicine (General) ,R5-920 - Abstract
Pnömomediastinum mediastene hava girişi ile oluşmaktadır. Çocuklarda genellikle astıma bağlıdır, ancak yenidoğanlarda pnömoni veya mekonyum aspirasyon sendromu predispozan faktörlerdir. Pnömomediastinum tanısı genellikle akciğer grafisi ile konur, yenidoğan bebeklerde pnömomediastinal hava ile kalbin üstündeki timik lopların yukarı ve dışa doğru sapmasıyla timusun yükseldiği yelken işareti görülür. Bebekler asemptomatik olabildiği gibi solunum sıkıntısına da neden olabilir. Pnömomediastinum genellikle bir veya iki haftada kendiliğinden resorbe olur. Burada pnömomediastinumlu iki yenidoğan bebek sunulmuştur. Her iki bebeğin göğüs filminde belirgin pnömomediastinum olmasına rağmen, solunum sıkıntısı orta düzeyde idi ve mediastinal hava spontan resorbe oldu.
- Published
- 2018
- Full Text
- View/download PDF
4. Neurological assessment of 38 late-diagnosed children with classic phenylketonuria
- Author
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Ali Topaloglu, Bilgin Yüksel, Güler Özer, Neslihan Mungan, Özlem Hergüner, Süreyya Soyupak, and Zeliha Haytoğlu
- Subjects
Medicine (General) ,R5-920 - Abstract
Purpose: We investigated the neurological outcome of 38 late-diagnosed phenylketonuria patients with magnetic resonance imaging (MRI), electroencephalography (EEG), visual evoked potentials (VEP), intelligence quotients (IQ) and examined the correlation of these parameters with the age and the plasma phenylalanine levels of patients at diagnosis.Material and Methods: Thirty-eight late-diagnosed classic phenylketonuria patients were enrolled in the study. Plasma phenylalanine levels were measured by spectrofluorometric method. MRI was evaluated by a pediatric neuroradiologist. Ankara developmental screening inventory (ADSI) and Wechsler intelligence scale for Turkish children (WISC-R) test were performed to detect IQ scores. Porteus Mazo test adapted for Turkish children intelligence test were performed to all children. The EEG of all patients were recorded. VEP was used to measure the electrical activity in the brain to visual stimulus. Results: The high plasma phenylalanine levels and late-diagnosis were associated with low IQ scores, pathological EEG, and pathological VEP patterns. High PA levels were also associated with more serious white matter signal abnormalities. Conclusion: Our results demonstrated the impact of early diagnosis and low levels of phenylalanine at diagnosis on the intellectual, neurological development and visual outcomes.
- Published
- 2016
5. Wilms Tümöründe Beş Yıllık Cerrahi Deneyim
- Author
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Önder ÖZDEN, Ender FAKIOĞLU, Murat ALKAN, Hilmi Serdar İSKİT, Recep TUNCER, Hasan OKUR, Serhan KÜPELİ, Şeyda ERDOĞAN, Süreyya SOYUPAK, and Ünal ZORLUDEMİR
- Subjects
wilms\' tumor ,children ,surgical treatment ,wilms tümörü ,çocuk ,cerrahi tedavi ,Medicine (General) ,R5-920 - Abstract
Amaç: Wilms tümörü tanısı konulan ve cerrahi tedavi uygulanan hastaların tedavi sonuçlarını değerlendirmek. Materyal ve Metod: 2008-2012 tarihleri arasında Wilms tümörü tanısıyla izlenen ve cerrahi tedavi uygulanan hastaların dosyaları retrospektif olarak incelendi. Cinsiyet, yaş, ek anomali birlikteliği, hastalığın evresi, ameliyat öncesi biyopsi alınıp alınmadığı, ameliyatın kemoterapi öncesi veya sonrası yapıldığı, histopatolojik özellikler, komplikasyonlar, ameliyat sırasında tümör rüptürü olup olmadığı ve sağkalım oranları irdelendi. Bulgular: Wilms tümörü tanısı ile ameliyat edilen toplam 31 hasta için Erkek/Kız oranı 0,7, ortalama yaş 3,1 yıldı (6 ay-11 yaş). Beş hastada konjenital ek anomali vardı. Tümör 13 hastada evre I, altışar hastada evre II ve III, üçer hastada evre IV ve V idi. Hastaların 11"ine ilk girişim olarak nefroüreterektomi, 11"ine biyopsi alınmadan neoadjuvan kemoterapi verildikten sonra nefroüreterektomi yapıldı. Sekiz hastada biyopsi ile tanı konuldu, kemoterapi verildi ve sonra nefroüreterektomi yapıldı. Bir hastada biyopsi alındıktan sonra tedavi verilmeden nefroüreterektomi uygulandı. Ameliyat sırasında iki hastada tümör rüptürü görüldü. Üç hastada cerrahi sınır pozitifti. Hastaların %68,9"unun histopatolojik tanısı trifazik Wilms tümörüydü. İki hastada postoperatif komplikasyon (menenjit ve pnömoni) gelişti. Üç hastada yineleme oldu. Ameliyat sonrası takip süresi ortalama 2,9 yıldı (1-6 yıl). Mortalite görülmedi. Sonuç: Cerrahi deneyimin artması, radyolojik görüntüleme tekniklerinin gelişmesi ve kemoterapi ile kitlelerin küçülmesi Wilms tümöründe tedaviyi kolaylaştırmakta ve sağkalım oranını arttırmaktadır.
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- 2014
- Full Text
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6. Pediatric Parapharyngeal Castleman’s Disease: a Case Report
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Fatih Erbey, İbrahim Bayram, Ülkü Tuncer, Süreyya Soyupak, and Atila Tanyeli
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Castleman’s disease ,parapharyngeal ,childhood ,Medicine - Abstract
Castleman’s disease is a rare lymphoproliferative disorder of unknown aetiology. It has two clinical expressions. The localized form, which usually presents as a slow growing mass and the multicentric form, where tumoural involvement is multilocated. Mediastinal involvement is the most common location of presentation. Parapharyngeal involvement is very rare and, to our knowledge, five pediatric parapharyngeal Castleman’s disease have been reported. We describe the case of a 14-year-old female child who was diagnosed as having parapharyngeal Castleman’s disease.
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- 2011
7. Pnömoni Tanısı ile Hastanede İzlenen Çocuk Hastaların Demografik, Klinik, Radyolojik Özelliklerinin ve Tedavi Sonuçlarının Değerlendirilmesi
- Author
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Merve Kılıç Çil, Özlem Özgür Gündeşlioğlu, Ümmühan Çay, Gülsüm Sönmez, Zahide Orhan Ok, Durdane Gaye Kocatepe, Süreyya Soyupak, Ceren Efe, İlker Ünal, Derya Alabaz, and Emine Kocabaş
- Subjects
Infectious Diseases ,Pediatrics, Perinatology and Child Health - Published
- 2022
- Full Text
- View/download PDF
8. Adrenal Insufficiency: An Extremely Rare Complication Due To Bilateral Neuroblastoma
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Gözde Atasever Yıldırım, Şeref Selçuk Kılıç, Süreyya Soyupak, Seyda Erdogan, and Serhan Küpeli
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- 2022
- Full Text
- View/download PDF
9. Evaluation of the Liver and Pancreas by 2D Shear Wave Elastography in Pediatric Wilson's Disease
- Author
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Sibel, Yavuz, Ferhat Can, Pişkin, Cemil, Oktay, Süreyya, Soyupak, and Gökhan, Tümgör
- Subjects
Hepatolenticular Degeneration ,Liver ,Elasticity Imaging Techniques ,Humans ,Original Article ,Child ,Pancreas ,Ultrasonography - Abstract
BACKGROUND: The primary aim of the study was to demonstrate parenchymal changes in the liver and pancreas related to copper accumulation using ultrasound in pediatric patients with Wilson’s disease and secondly, to investigate the effectiveness of two-dimensional shear wave elastography in the diagnosis of involvement of these organs. METHODS: Patients with Wilson’s disease (n = 25) who were treated and followed at our center were evaluated prospectively. In addition to routine clinical assessments, eye examination, laboratory analyses, and abdominal ultrasound imaging, all patients underwent tissue stiffness measurements from the liver and pancreas (head, body and tail) by two-dimensional shear wave elastography. The data obtained from the WD patients were compared with those of age- and sex-matched healthy controls (n = 37). RESULTS: Liver elastography measurements showed significantly increased tissue stiffness in the patient group than in control subjects (P < .001). While there was no significant difference between the groups in the tissue thickness of pancreatic head, body, and tail, tissue stiffness was significantly reduced in the patient group (P < .001). Disease duration was significantly associated and moderately correlated with liver tissue stiffness (r = 0.417, P = .038) but not significantly associated with pancreatic tissue stiffness. CONCLUSION: In the early stages of Wilson’s disease, parenchymal changes occur in the liver and pancreas, which cannot be detected by conventional ultrasonography imaging but may be demonstrated by two-dimensional shear wave elastography. Ultrasound elastography is an easy to use, non-invasive, and promising method that provides numerical data on the early changes in tissue stiffness, allowing for objective monitoring of Wilson’s disease patients who require lifelong follow-up.
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- 2022
10. Evaluation of high resolution computed tomography findings of cystic fibrosis
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Derya Ufuk Altintas, Gülşah Ayçin Duyuler, Mustafa Yilmaz, Dilek Dogruel, Mahir Serbes, Ayşe Şenay Şaşihüseyinoğlu, Süreyya Soyupak, and Çukurova Üniversitesi
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Male ,Vital capacity ,High-resolution computed tomography ,Percentile ,Pulmonology ,Adolescent ,Cystic Fibrosis ,Physical examination ,Pulmonary evaluation ,Pulmonary function testing ,03 medical and health sciences ,FEV1/FVC ratio ,0302 clinical medicine ,Pulmonary evaluatio ,Humans ,Medicine ,Child ,Computed tomography ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,Infant ,respiratory system ,respiratory tract diseases ,Child, Preschool ,Sputum ,Original Article ,Female ,Radiography, Thoracic ,030211 gastroenterology & hepatology ,medicine.symptom ,Tomography, X-Ray Computed ,business ,Nuclear medicine ,Body mass index - Abstract
PubMedID: 29976036 Background/Aims: Morphological changes due to lung disease in patients with cystic fibrosis (CF) were evaluated using high resolution computed tomography (HRCT), and the HRCT scores obtained using the Bhalla scoring system were correlated with those obtained using clinical and laboratory indicators. Methods: Medical records of 28 children with CF who underwent chest CT in Department of Pediatric Allergy and Immunology, Cukurova University Balcali Hospital between March 2011 and January 2016 were retrospectively reviewed. Demographic data and physical examination, respiratory cultures, pulmonary function tests, and chest HRCT findings were evaluated. Patients were divided into the following two groups according to their forced expiratory volume in the first second (FEV 1 ) values: normal FEV 1 (? 80% of predicted values) and low FEV 1 (< 80% of predicted values). Deep throat or sputum cultures were evaluated for the presence of Pseudomonas aeruginosa (PsA) and other bacteria. HRCT scans were scored using the Bhalla scoring system. Results: No significant correlation was found between the Bhalla scores and sex, age group, or height percentiles. Significant relationships were found between the Bhalla score and weight (p = 0.036) and body mass index (BMI) (p = 0.032) percentiles below the third percentile, bacterial growth in the sputum/ deep throat cultures (p = 0.009), and presence of PsA (p = 0.004). Moreover, a significant correlation was found between the Bhalla score and FEV 1 (r = -0.315, p = 0.0272), forced vital capacity (FVC; r = -0.381, p = 0.0178), forced expiratory flow between 25% and 75% of FVC (r = -0.229, p = 0.0431), and BMI (r = -3.368, p = 0.050). Conclusions: Chest HRCT is an important diagnostic tool for the pulmonary evaluation of children with CF. © 2019 The Korean Association of Internal Medicine.
- Published
- 2019
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11. Ultrasonographic measurement of the dimensions of proximal and distal patellar fragments after Niebauer-King Procedure for the management of congenital dislocation of the knee
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Ömer Faruk Eren, Süreyya Soyupak, Mustafa Tekin, Mehmet Ali Deveci, Ömer Sunkar Biçer, Akif Mirioğlu, Deveci, Mehmet Ali (ORCID 0000-0002-3670-3985 & YÖK ID 206311), Biçer, Ö. S., Tekin, M., Eren, Ö. F., Mirioğlu, A., Soyupak, S., and School of Medicine
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musculoskeletal diseases ,Knee Dislocation ,Knee Joint ,Patellar Dislocation ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Child ,Retrospective Studies ,Orthopedic surgery ,Quadricepsplasty ,Arthrogryposis multiplex ,Ultrasonography ,Arthrogryposis multiplex congenita ,business.industry ,Knee contractures ,Infant ,Mean age ,Level iv ,General Medicine ,Anatomy ,Patella ,Orthopedics ,Child, Preschool ,Surgery ,Female ,Joint Diseases ,business ,RD701-811 - Abstract
Objective: the aim of this study was to ultrasonographically measure the dimensions of the proximal and distalpatellar fragments to determine whether postoperative growth differences existbetween the fragments in children with congenital dislocation of the kneetreated by Niebauer Kings quadricepsplasty. Methods: this retrospective study included six congenitaldislocated knees of four children with arthrogryposis multiplex congenita (AMC)(3 girls; mean age = 40 months; age range = 9-44 months), presented with severe hyperextension knee contractures,which were treated by Niebauer-King's quadricepsplasty.The transverse, craniocaudal, and anteroposterior dimensions of the patellaewere measured ultrasonographically 20 (range = 6-42) months postoperatively by a singleradiologist. Results: the mean transverse, craniocaudal, and anteroposteriordimensions of proximal and distal halves of the patellae were: 11.46 (7.0-16.9)-10.5 (8.0-14.4); 17.4 (14.0-21.0) -16.68 (14.5-19.3); 6.76 (5.6-7.9) -7.76 (7.0-9.4) mm respectively. There was no significantdifference in craniocaudal and transverse dimensions, but the anteroposteriordimension (thickness) of the distal patellae articulating the knee joint had agreater thickness (P = 0,01). Conclusion: evidence from this study has shown that a bettergrowth can be expected in the distal fragment of the patella compared with theproximal fragment following treatment with Niebauer-King's quadricepsplasty in children with congenital dislocation ofthe knee., NA
- Published
- 2021
12. Spontaneous resolution of pneumomediastinum in two newborn babies
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Hilmi Serdar İskit, Hacer Yapıcıoğlu Yıldızdaş, Mustafa Akçalı, Ferda Özlü, Nejat Narli, Önder Özden, Süreyya Soyupak, Mehmet Satar, Gülseren Bilen Yurdakul, and Çukurova Üniversitesi
- Subjects
Biyokimyasal Araştırma Metotları ,Alerji ,Farmakoloji ve Eczacılık ,Anestezi ,Toksikoloji ,Biyofizik ,Pnömomediasten,Tanısal,Bebek,Yenidoğan ,Pneumomediastinum,Diagnosis,Newborn ,Diş Hekimliği ,Adli Tıp ,Acil Tıp ,Health Care Sciences and Services ,Androloji ,Biyokimya ve Moleküler Biyoloji ,General Earth and Planetary Sciences ,Anatomi ve Morfoloji ,Sağlık Bilimleri ve Hizmetleri ,General Environmental Science - Abstract
Pneumomediastinum is due to air penetration in to the mediastinum. In children it is mostly due to asthma, however in newborns pneumonia or meconium aspiration syndrome are the predisposing factors. Pneumomediastinum is recognised by chest radiography, in newborn babies -spinnaker sign- an upwards and outwards deviation of thymic lobes can be seen due to raising of thymus above the heart by pneumomediastinal air. Babies may be asymptomatic or they may have respiratory distress. Pneumomediastinum usually resorbs spontaneously over one or two weeks. Here we report two newborn babies with pneumomediastinum. Although pneumomediastinum was obvious in the chest X-rays, both babies had mild respiratory distress and mediastinal air resorbed spontaneously., Pnömomediastinum mediastene hava girişi ile oluşmaktadır. Çocuklarda genellikle astıma bağlıdır, ancak yenidoğanlarda pnömoni veya mekonyum aspirasyon sendromu predispozan faktörlerdir. Pnömomediastinum tanısı genellikle akciğer grafisi ile konur, yenidoğan bebeklerde pnömomediastinal hava ile kalbin üstündeki timik lopların yukarı ve dışa doğru sapmasıyla timusun yükseldiği yelken işareti görülür. Bebekler asemptomatik olabildiği gibi solunum sıkıntısına da neden olabilir. Pnömomediastinum genellikle bir veya iki haftada kendiliğinden resorbe olur. Burada pnömomediastinumlu iki yenidoğan bebek sunulmuştur. Her iki bebeğin göğüs filminde belirgin pnömomediastinum olmasına rağmen, solunum sıkıntısı orta düzeyde idi ve mediastinal hava spontan resorbe oldu.
- Published
- 2018
- Full Text
- View/download PDF
13. A rare cause of granulomatous hepatitis: Tularemia
- Author
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Figen Doran, Ümmühan Çay, Emine Kocabaş, Merve Kılıç Çil, Süreyya Soyupak, and Özlem Özgür Gündeşlioğlu
- Subjects
0301 basic medicine ,Male ,Abdominal pain ,Turkey ,Hepatitis ,Tularemia ,0302 clinical medicine ,Zoonoses ,Medicine ,030212 general & internal medicine ,Child ,Francisella tularensis ,Ultrasonography ,Granuloma ,biology ,medicine.diagnostic_test ,lcsh:Public aspects of medicine ,General Medicine ,Jaundice ,respiratory system ,Anti-Bacterial Agents ,Infectious Diseases ,Treatment Outcome ,Liver biopsy ,Granulomatous Hepatitis ,medicine.symptom ,medicine.medical_specialty ,030106 microbiology ,complex mixtures ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,Animals ,Humans ,lcsh:RC109-216 ,Granulomatous hepatitis ,Suppuration ,business.industry ,Public Health, Environmental and Occupational Health ,lcsh:RA1-1270 ,medicine.disease ,biology.organism_classification ,bacterial infections and mycoses ,Dermatology ,Etiology ,Elevated transaminases ,bacteria ,Lymph Nodes ,business - Abstract
Tularemia is a zoonotic infection caused by Francisella tularensis. Tularemia has several clinical form in humans, including ulceroglandular, pneumonic, oropharyngeal, oculoglandular, and systemic (typhoidal). Tularemia may develop granulomatous and suppurative lesions, especially in the affected regional lymph nodes and various organs. Patients with hepatic involvement typically have elevated transaminase levels, hepatomegaly and rarely jaundice. Histologically, there are typically suppurative microabscesses with occasional surrounding macrophages. Rarely, hepatic granuloma can develop due to tularemia. We present a case of an 8 year-old male residing in a rural village in Turkey, who came to our hospital after having intermittent fever for four months and right upper abdominal pain for two months. Liver had a nodular appearance in liver imaging and liver biopsy were consistent with granulomatous hepatitis. The microagglutination test was positive for tularemia in the patient who was investigated for granulomatous hepatitis etiology. Symptoms and signs improved with tularemia treatment. We present a rare case of hepatic involvement of tularemia in a child. Clinicians should be suspicious of and evaluate for typhoidal tularemia in patients who present with prolonged fever and non-specific systemic symptoms, potentially with associated abdominal pain.
- Published
- 2019
14. Bone Disease and Serum Fibroblast Growth Factor-23 Levels in Renal Transplant Recipients
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Mustafa Balal, Y. Coskun, Ertan Kara, Saime Paydas, Süreyya Soyupak, and Çukurova Üniversitesi
- Subjects
Adult ,Male ,musculoskeletal diseases ,medicine.medical_specialty ,Bone density ,Bone disease ,Osteoporosis ,030232 urology & nephrology ,Renal function ,030204 cardiovascular system & hematology ,Kidney Function Tests ,Gastroenterology ,03 medical and health sciences ,chemistry.chemical_compound ,Absorptiometry, Photon ,0302 clinical medicine ,Bone Density ,Internal medicine ,medicine ,Humans ,Kidney transplantation ,Aged ,Transplantation ,Creatinine ,business.industry ,Middle Aged ,medicine.disease ,Kidney Transplantation ,Fibroblast Growth Factors ,Osteopenia ,Fibroblast Growth Factor-23 ,chemistry ,Parathyroid Hormone ,Immunology ,Cyclosporine ,Kidney Failure, Chronic ,Female ,Surgery ,business ,Kidney disease - Abstract
PubMedID: 27569941 Background Posttransplantation bone disease develops commonly and results in important complications. In this study, we aimed to investigate the relationship between bone diseases and serum fibroblast growth factor-23 (FGF-23) in renal transplant recipients. Methods This study was conducted in 106 kidney transplant recipients (KTrs; group G1) and 30 patients with chronic kidney disease (group G2). Patients with fever, heart failure, angina pectoris, acute renal failure, malignant disease, or any gastrointestinal disease were excluded. KTrs were treated with triple immunosuppressive drugs including glucocorticoids. Complete blood count (CBC), blood urea nitrogen (BUN), creatinine, glomerular filtration rate (GFR, Modification of Diet in Renal Disease [MDRD] formula), lipid profile, calcium (Ca), phosphorous (P), parathormone (PTH), 25OHD3, serum levels of tacrolimus/cyclosporine, and intact FGF-23 were measured. Bone mineral density (BMD) was measured with dual energy X-ray absorptiometry. Results The mean patient age was 40.1 ± 11.1 years and 39.2 ± 11.3 years in G1 and G2, respectively (P >.05). In G1 and G2, 76 and 15 patients were male, respectively. Compared with the G2 patients, G1 patients had lower body mass index (BMI), serum glucose levels, P, Mg, and Ca·P (P 1.5 mg/dL was lower than that in patients with serum creatinine 1.5 mg/dL. In long-term follow-up of renal transplantation by as much as 58 months, the incidence of bone disease such as osteoporosis/osteopenia was as high as 67% and was also higher than that of nontransplant patients with similar GFR. In addition to decreased renal function, dyslipidemia, inflammation, and continuing hypophosphatemia were also accompanied by decreased BMD as in cardiovascular disease in KTrs. © 2016
- Published
- 2016
- Full Text
- View/download PDF
15. Neurological assessment of 38 late-diagnosed children with classic phenylketonuria
- Author
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Zeliha Haytoğlu, Özlem Hergüner, Süreyya Soyupak, Ali Kemal Topaloğlu, Bilgin Yüksel, Güler Özer, H. Neslihan Mungan Önenli, and Çukurova Üniversitesi
- Subjects
lcsh:R5-920 ,lcsh:R ,lcsh:Medicine ,Late-diagnosed Phenylketonuria ,Magnetic resonans imaging ,Visual evoked potential ,lcsh:Medicine (General) ,Cerrahi - Abstract
Amaç: Geç tanı alan fenilketonuri hastalarında manyetik rezonans görüntüleme (MRG), elektroensefalografi (EEG), uyarılmış görsel potansiyeller (VEP) ve zeka katsayısı ile nörolojik açıdan etkilenme ve bu parametrelerin tanı yaşı ve kan fenilalanin düzeyi ile korelasyonu araştırıldı. Gereç ve Yöntem: Çukurova Üniversitesi Tıp Fakültesi, Çocuk Metabolizma ve Beslenme Bilim Dalında başvuran geç tanı almış 38 klasik fenilketonurili hasta çalışmaya alındı. Kan fenilalanin düzeyleri spektroflorometrik yöntem ile ölçüldü. Ankara gelişim tarama envanteri (AGTE), Türk çocuklarına göre uyarlanmış Wechesler zeka testi (WISC-R) yaş gruplarına uygun olarak yapıldı. Tüm çocuklara Türk çocuklarına göre uyarlanmış Porteus Maze zeka testi uygulandı. Tüm çocuklara EEG kaydı yapıldı. Merkezi sinir sisteminin görsel uyaranlara verdiği yanıt VEP ile değerlendirildi. MRG ile santral sinir sistemi bulguları incelendi. Bulgular: Yüksek plazma fenilalanin düzeyi ve geç tanı, düşük zeka katsayısı, patolojik EEG, patolojik VEP ile ilişkili bulundu. Yüksek fenilalanin düzeyi ciddi beyaz cevher sinyal değişiklikleri ile ilişkiliydi. Sonuç: Çalışmamız erken tanının ve tanı anındaki düşük kan fenilalanin düzeyinin entellektüel , nörolojik gelişim ve görme üzerine olan etkisini göstermiştir. Purpose: We investigated the neurological outcome of 38 late-diagnosed phenylketonuria patients with magnetic resonance imaging (MRI), electroencephalography (EEG), visual evoked potentials (VEP), intelligence quotients (IQ) and examined the correlation of these parameters with the age and the plasma phenylalanine levels of patients at diagnosis. Material and Methods: Thirty-eight late-diagnosed classic phenylketonuria patients were enrolled in the study. Plasma phenylalanine levels were measured by spectrofluorometric method. MRI was evaluated by a pediatric neuroradiologist. Ankara developmental screening inventory (ADSI) and Wechsler intelligence scale for Turkish children (WISC-R) test were performed to detect IQ scores. Porteus Mazo test adapted for Turkish children intelligence test were performed to all children. The EEG of all patients were recorded. VEP was used to measure the electrical activity in the brain to visual stimulus. Results: The high plasma phenylalanine levels and latediagnosis were associated with low IQ scores, pathological EEG, and pathological VEP patterns. High PA levels were also associated with more serious white matter signal abnormalities. Conclusion: Our results demonstrated the impact of early diagnosis and low levels of phenylalanine at diagnosis on the intellectual, neurological development and visual outcomes.
- Published
- 2016
16. Stroke in a Pediatric Immune Thrombocytopenia Case
- Author
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Süreyya Soyupak, Hatice Şaşmaz, Yurdanur Kilinç, Metin Cil, Göksel Leblebisatan, and Çukurova Üniversitesi
- Subjects
Pediatric intensive care unit ,Pediatrics ,medicine.medical_specialty ,business.industry ,Cerebral infarction ,Immunology ,Cell Biology ,Hematology ,medicine.disease ,Biochemistry ,Thrombosis ,Bleeding diathesis ,medicine ,Refractory Thrombocytopenia ,Thrombus ,Complication ,business ,Stroke - Abstract
Objective: Immune thrombocytopenia is a bleeding disorder related to deficiency of the main element in primary hemostasis, platelets. But it rarely results in an opposite clinical complication as thrombosis. The mechanism of this unexpected complication is not fully understood still and the treatment of the patients in this thrombocytopenic and thrombotic condition is critical and hard to manage. Here we present a case of immune thrombocytopenia with cerebral infarct with his clinical management details. Case: A seven-year old boy diagnosed with Immune thrombocytopenia at the age of 1 in another clinic and treated with IVIG when the platelet levels fell and bleeding symptoms appeared. The patient refered to our clinic with severe refractory thrombocytopenia. After being diagnosed with ITP, IVIG treatment and HDDXM treatment (20 mg/m2/day for 4 days) was given 2 cure in a month then the patient follow up in the clinic. It is learned that the family continued with HDDXM and sometimes IVIG treatment when needed in the local hospital. When the child was 6 years old, because of inability to walk and talk he was referred and it was revealed that he had cerebral infarct in the ICA area with a platelet level of 11000/mm3. He was followed in pediatric ICU. He was treated with thrombocytopenia with replacement and steroids in addition to physical treatment for stroke. Anticoagulation was used as the clinical and laboratory picture allowed. Result: The patient was discharged with the better clinical Picture and his chronic treatment planned mostly with steroids. Conclusion: Stroke in the immune thrombocytopenic clinic is a rare but hard to manage condition. Although its mechanism not understand well, the clinician should be identify and manage it carefully. Disclosures No relevant conflicts of interest to declare.
- Published
- 2018
17. Wilms Tümöründe Beş Yıllık Cerrahi Deneyim
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Süreyya Soyupak, Serhan Küpeli, Recep Tuncer, Ünal Zorludemir, Murat Alkan, Ender Fakıoğlu, Seyda Erdogan, Hasan Okur, Önder Özden, Hilmi Serdar İskit, and Çukurova Üniversitesi
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Gynecology ,medicine.medical_specialty ,lcsh:R5-920 ,wilms tümörü ,business.industry ,wilms\' tumor ,surgical treatment ,cerrahi tedavi ,Wilms' tumor ,General Medicine ,medicine.disease ,çocuk ,children ,Medicine ,Surgical treatment ,business ,lcsh:Medicine (General) ,Cerrahi - Abstract
Amaç: Wilms tümörü tanısı konulan ve cerrahi tedavi uygulanan hastaların tedavi sonuçlarını değerlendirmek. Materyal ve Metod: 2008-2012 tarihleri arasında Wilms tümörü tanısıyla izlenen ve cerrahi tedavi uygulanan hastaların dosyaları retrospektif olarak incelendi. Cinsiyet, yaş, ek anomali birlikteliği, hastalığın evresi, ameliyat öncesi biyopsi alınıp alınmadığı, ameliyatın kemoterapi öncesi veya sonrası yapıldığı, histopatolojik özellikler, komplikasyonlar, ameliyat sırasında tümör rüptürü olup olmadığı ve sağkalım oranları irdelendi. Bulgular: Wilms tümörü tanısı ile ameliyat edilen toplam 31 hasta için Erkek/Kız oranı 0,7, ortalama yaş 3,1 yıldı (6 ay11 yaş). Beş hastada konjenital ek anomali vardı. Tümör 13 hastada evre I, altışar hastada evre II ve III, üçer hastada evre IV ve V idi. Hastaların 11'ine ilk girişim olarak nefroüreterektomi, 11'ine biyopsi alınmadan neoadjuvan kemoterapi verildikten sonra nefroüreterektomi yapıldı. Sekiz hastada biyopsi ile tanı konuldu, kemoterapi verildi ve sonra nefroüreterektomi yapıldı. Bir hastada biyopsi alındıktan sonra tedavi verilmeden nefroüreterektomi uygulandı. Ameliyat sırasında iki hastada tümör rüptürü görüldü. Üç hastada cerrahi sınır pozitifti. Hastaların %68,9'unun histopatolojik tanısı trifazik Wilms tümörüydü. İki hastada postoperatif komplikasyon (menenjit ve pnömoni) gelişti. Üç hastada yineleme oldu. Ameliyat sonrası takip süresi ortalama 2,9 yıldı (1-6 yıl). Mortalite görülmedi. Sonuç: Cerrahi deneyimin artması, radyolojik görüntüleme tekniklerinin gelişmesi ve kemoterapi ile kitlelerin küçülmesi Wilms tümöründe tedaviyi kolaylaştırmakta ve sağkalım oranını arttırmaktadır. Purpose: To evaluate the treatment results of the patients operated with diagnosis of Wilms' tumor . Materials and Methods: The records of patients operated for Wilms' tumor in 2008-2012 were evaluated retrospectively. Sex, age, additional anomalies, tumor stages, preoperative biopsy and chemotherapy history, histopathological features, preoperative tumor rupture, complications and survival rates were reviewed Results: Male/Female ratio of total 31 patients operated due to Wilms' tumor was 0.7 and mean age was 3.1 years (6 months - 11 years). Five of the patients had additional congenital anomalies. Thirteen patients had stage I tumor, 6 had stage II, 6 had stage III, 3 had stage IV and 3 had stage V. Eleven of the patients underwent immediate nephrouretectomy as a first intervention, eleven patients went through delayed nephrouretectomy after neoadjuvant chemotherapy without biopsy, eight patients were diagnosed via biopsy and underwent delayed nephrectomy after neoadjuvant chemotherapy. One of the patients went through immediate nephrouretectomy with biopsy. The histopathologic examination of 68,9% of the patients reported as triphasic Wilms' tumor. Three patients had positive surgical margins. Peroperative spillage was experienced in two patients. Two patients had postoperative complications (pneumonia and meningitis) and three patients had tumor relapses. Mean follow-up period was 2.9 years (1-6 years) and no mortality was observed. Conclusion: Increased surgical experience, development of radiologic imaging techniques and chemotherapeutic reduction of tumor size make treatment of Wilms' tumor easier and increase the survival rate. Anahtar Kelimeler: Wilms' tumor, children, surgical treatment.
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- 2014
18. Infantile rhabdoid tumor mimicking hepatic hemangioendothelioma
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Serhan Küpeli, Süreyya Soyupak, Ahmet Yontem, Nejat Narli, Figen Doran, and Çukurova Üniversitesi
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Pathology ,medicine.medical_specialty ,Text mining ,Oncology ,business.industry ,Medicine ,Radiology, Nuclear Medicine and imaging ,General Medicine ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,business ,lcsh:RC254-282 ,Hepatic hemangioendothelioma - Abstract
PubMedID: 27072279 [No abstract available]
- Published
- 2016
19. Neurological assessment of 38 late-diagnosed children with classic phenylketonuria
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Süreyya Soyupak, Ozlem M Herguner, Güler Özer, Ali Kemal Topaloglu, Zeliha Haytoğlu, Bilgin Yüksel, and H. Neslihan Önenli Mungan
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0301 basic medicine ,Gynecology ,medicine.medical_specialty ,Pediatrics ,genetic structures ,business.industry ,Classic phenylketonuria ,General Medicine ,030105 genetics & heredity ,03 medical and health sciences ,Neurological assessment ,0302 clinical medicine ,medicine ,business ,030217 neurology & neurosurgery - Abstract
Purpose: We investigated the neurological outcome of 38 late-diagnosed phenylketonuria patients with magnetic resonance imaging (MRI), electroencephalography (EEG), visual evoked potentials (VEP), intelligence quotients (IQ) and examined the correlation of these parameters with the age and the plasma phenylalanine levels of patients at diagnosis.Material and Methods: Thirty-eight late-diagnosed classic phenylketonuria patients were enrolled in the study. Plasma phenylalanine levels were measured by spectrofluorometric method. MRI was evaluated by a pediatric neuroradiologist. Ankara developmental screening inventory (ADSI) and Wechsler intelligence scale for Turkish children (WISC-R) test were performed to detect IQ scores. Porteus Mazo test adapted for Turkish children intelligence test were performed to all children. The EEG of all patients were recorded. VEP was used to measure the electrical activity in the brain to visual stimulus. Results: The high plasma phenylalanine levels and late-diagnosis were associated with low IQ scores, pathological EEG, and pathological VEP patterns. High PA levels were also associated with more serious white matter signal abnormalities. Conclusion: Our results demonstrated the impact of early diagnosis and low levels of phenylalanine at diagnosis on the intellectual, neurological development and visual outcomes., Amaç: Geç tanı alan fenilketonuri hastalarında manyetik rezonans görüntüleme (MRG), elektroensefalografi (EEG), uyarılmış görsel potansiyeller (VEP) ve zeka katsayısı ile nörolojik açıdan etkilenme ve bu parametrelerin tanı yaşı ve kan fenilalanin düzeyi ile korelasyonu araştırıldı.Gereç ve Yöntem: Çukurova Üniversitesi Tıp Fakültesi, Çocuk Metabolizma ve Beslenme Bilim Dalında başvuran geç tanı almış 38 klasik fenilketonurili hasta çalışmaya alındı. Kan fenilalanin düzeyleri spektroflorometrik yöntem ile ölçüldü. Ankara gelişim tarama envanteri (AGTE), Türk çocuklarına göre uyarlanmış Wechesler zeka testi (WISC-R) yaş gruplarına uygun olarak yapıldı. Tüm çocuklara Türk çocuklarına göre uyarlanmış Porteus Maze zeka testi uygulandı. Tüm çocuklara EEG kaydı yapıldı. Merkezi sinir sisteminin görsel uyaranlara verdiği yanıt VEP ile değerlendirildi. MRG ile santral sinir sistemi bulguları incelendi. Bulgular: Yüksek plazma fenilalanin düzeyi ve geç tanı, düşük zeka katsayısı, patolojik EEG, patolojik VEP ile ilişkili bulundu. Yüksek fenilalanin düzeyi ciddi beyaz cevher sinyal değişiklikleri ile ilişkiliydi. Sonuç: Çalışmamız erken tanının ve tanı anındaki düşük kan fenilalanin düzeyinin entellektüel , nörolojik gelişim ve görme üzerine olan etkisini göstermiştir
- Published
- 2015
20. Normal transcranial doppler flow parameters in children: Implementation of doppler imaging with angle correction
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Süreyya Soyupak, Tuğsan Balli, Cigdem Yalçin, Figen Binokay, Gulsah Seydaoglu, Seda N. Çiçekçi, Kairgueldy Aikimbaev, and Çukurova Üniversitesi
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blood flow velocity ,pediatric ,Flow (mathematics) ,business.industry ,Medicine ,Surgery ,Neurology (clinical) ,reference values ,business ,Doppler imaging ,Transcranial Doppler ultrasonography ,Transcranial Doppler ,Biomedical engineering - Abstract
Purpose: This study was conducted to identify normal reference values of basal cerebral artery blood flow velocities in healthy children and adolescents and determine influence of age and sex on normal values. Materials and Methods: A total of 129 healthy children were evaluated within the childhood and adolescence period by color transcranial sonography. Blood flow velocities and Doppler indices were determined in the anterior cerebral, middle cerebral, posterior cerebral, vertebral arteries, and basilar arteries. Measurements were correlated with the age and sex of the children. Results: Normal values of blood flow velocities for cerebral arteries according to age and sex were obtained and presented in tables. Side differences are also indicated and values are given in relation to age and sex. The flow velocities rapidly increase in children (from 3 up to 11 y) and gradually decrease with increased age. The resistance indices decrease in children and increase in older people. Conclusion: The changing intracranial hemodynamics during childhood and adolescence require age-dependent reference values to distinguish physiological and pathologic flow velocities in the basal cerebral arteries. The tables according to age and sex will definitely be helpful in managing cerebral hemodynamics in children. © 2013 Wolters Kluwer Health, Inc. All rights reserved.
- Published
- 2015
21. Spectrum of Extrapulmonary Tuberculosis: Radiologic Manifestations
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Figan Binokay, Süreyya Soyupak, Mehmet Inal, Erol Akgül, Mahmut Oğuz, Kenon Bicakci, and Çukurova Üniversitesi
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medicine.medical_specialty ,Tuberculosis ,Genitourinary system ,business.industry ,Extrapulmonary tuberculosis ,Osteomyelitis ,medicine.disease ,Dermatology ,medicine.anatomical_structure ,medicine ,Monoarthritis ,Radiology, Nuclear Medicine and imaging ,business ,Vertebral column - Abstract
Extrapulmonary tuberculosis mostly affects musculoskeletal, genitourinary, gastrointestinal, and central nervous systems. In the musculoskeletal system, tuberculosis manifests characteristically as monoarthritis or osteomyelitis that most frequently involves the vertebral column, hip, and knee. Genitourinary involvement usually begins in the upper tracts as tuberculous pyelonephritis and spreads out to the lower tract along the uroepithelial mucosa. Tuberculosis may involve the gastrointestinal tract, hepatobiliary system, and mesenteric or peritoneal structures in the abdominal cavity. Within the central nervous system, tuberculosis may manifest as meningitis or mass lesions, such as tuberculoma or tuberculous brain abscesses. Rare reported sites of tuberculous involvement include the eye, larynx, paranasal sinuses, pericardium, and breast. Since tuberculous involvement in any system or organ may be confused with many other pathology, both clinically and radiologically, radiologists should be aware of the different radiographic appearances of this protean but curable disease and should consider it in the differential diagnosis.
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- 2003
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22. Benign rectal schwannoma
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Kenan Bicakci, Süreyya Soyupak, Mehmet Inal, Erol Akgül, Figen Binokay, and Çukurova Üniversitesi
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medicine.medical_specialty ,Schwannoma ,medicine.diagnostic_test ,business.industry ,Rectum ,Computed tomography ,Magnetic resonance imaging ,medicine.disease ,Nerve sheath tumor ,Flouroscopy ,medicine.anatomical_structure ,otorhinolaryngologic diseases ,medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,business - Abstract
Schwannoma is a rare nerve sheath tumor which frequently occurs in the intracranial acoustic nerve and spinal nerves. It is extremely rare in the rectum. In this report, we present a case of benign rectal schwannoma with the findings of flouroscopy, computed tomography and magnetic resonance imaging. © 2002 Elsevier Science Ireland Ltd. All rights reserved.
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- 2003
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23. Osteopenia and osteoporosis in postmenopausal women. Assessment by radiogrammetric measurement
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Figen Binokay, Erkan Kozanoglu, Medih Çeliktaş, Kairgueldy Aikimbaev, Süreyya Soyupak, and Çukurova Üniversitesi
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medicine.medical_specialty ,Bone disease ,Radiography ,Osteoporosis ,Dentistry ,Wrist ,Sensitivity and Specificity ,Femoral head ,Absorptiometry, Photon ,Bone Density ,Bone mineral density ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Carpal Bones ,Osteoporosis, Postmenopausal ,Aged ,Femoral neck ,Radiological and Ultrasound Technology ,Osteopenia ,Femur Neck ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Spine ,Vertebra ,Bone Diseases, Metabolic ,medicine.anatomical_structure ,ROC Curve ,Female ,Radiology ,Metacarpus ,business ,Radiogrammetry ,hormones, hormone substitutes, and hormone antagonists - Abstract
Purpose: To compare the ability of the medial cortical thickness ratio to the width of the second metacarpal bone at the midshaft (MCR) in discriminating patients as normal, osteopenic or osteoporotic. Material and Methods: MCR was calculated from radiographs of 120 postmenopausal women. By dual-energy X-ray absorptiometry, the mineral density was measured in the lumbar spine, the wrist and the femoral neck. Patients were grouped in accordance with the diagnostic criteria of WHO on the basis of t-scores. MCR values were compared with t-scores and the ability of the MCR technique in discriminating the patient groups was evaluated. Results: Analysis of radiogrammetric data revealed significant differences in MCR value between the 3 groups. The MCR was lower in patients with osteoporosis and osteopenia compared with the normal group. The mean value of MCR was also slightly lower in patients with osteoporosis than in those with osteopenia. Accuracy assessment (ROC analysis) of MCR in the discrimination of patients with osteoporosis showed that test accuracy was acceptable, but less accurate than spinal, wrist and femoral neck t-scores. Compared with t-scores, this test was found to fairly discriminate those with and without osteopenia. Conclusion: The MCR method can discriminate patients as osteoporotic or normal. However, it seems that the MCR method should not be used for decisions concerning treatment of osteoporosis because of its low accuracy and thereby a risk for misclassification.
- Published
- 2002
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24. Sonographic measurements of the liver, spleen and kidney dimensions in the healthy term and preterm newborns
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Nejat Narli, Süreyya Soyupak, Erol Aksungur, Hacer Yapıcıoğlu, Mehmet Satar, and Çukurova Üniversitesi
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Male ,medicine.medical_specialty ,Physiology ,Gestational Age ,Spleen ,Kidney ,Reference Values ,Internal medicine ,Ultrasound ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Ultrasonography ,business.industry ,Body Weight ,Infant, Newborn ,Gestational age ,General Medicine ,Newborn ,Endocrinology ,medicine.anatomical_structure ,Liver ,Reference values ,Recien nacido ,Female ,business ,Infant, Premature ,Cohort study - Abstract
PubMedID: 12065125 This study was conducted in order to assess normal liver, spleen and kidney dimensions in premature and term newborns and determine the acceptable range. A total of 253 (99 preterm and 154 term) healthy newborns were evaluated within the first week of life by sonography. Gestational age ranged from 24 to 41 weeks, weight ranged from 638 to 4800 g. Measurements were compared with gestational age, weight and height of the infants. Normal ranges for kidney, liver and spleen measurements according to gestational age and weight were obtained. We found that weight showed the best correlation with any one of the mentioned organ dimensions. © 2002 Elsevier Science Ireland Ltd. All rights reserved.
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- 2002
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25. Vitamin D Status and Bone Mineral Density of Veiled and Unveiled Turkish Women
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Süreyya Soyupak, Fusun Guler-Uysal, Tunay Sarpel, Rengin Güzel, Erkan Kozanoglu, and Çukurova Üniversitesi
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Adult ,musculoskeletal diseases ,medicine.medical_specialty ,Adolescent ,Turkey ,Bone density ,Population ,Osteoporosis ,Islam ,Clothing ,Bone remodeling ,Bone Density ,Internal medicine ,medicine ,Vitamin D and neurology ,Humans ,Vitamin D ,education ,Bone mineral ,Osteomalacia ,education.field_of_study ,business.industry ,General Medicine ,Vitamin D Deficiency ,medicine.disease ,Endocrinology ,Case-Control Studies ,Dietary Supplements ,Sunlight ,Female ,business ,Body mass index - Abstract
PubMedID: 11703889 The aim of the study is to compare vitamin D status and bone mineral density (BMD) in veiled and unveiled healthy Turkish women of reproductive age. Thirty young to middle-aged volunteer veiled women and 30 age-matched control subjects with western clothing habits were enrolled in the study. The two groups had similar dietary habits, body mass index (BMI) distribution, and gestational history. Physical and laboratory examinations were performed to rule out any disease that could affect bone metabolism. Serum 25-hydroxyvitamin D (25-OHD) levels were measured, and BMD of the spine and hip were investigated by dual energy x-ray absorptiometry (DEXA). The mean age of dressing the veil was 15.7 ± 6.13 years, and 66.7% of the veiled women claimed that they were not ever exposed to direct sunlight, as they were leading an indoor life. Compared with the control group, veiled women were less educated and physically less active (p < 0.001 and p < 0.05, respectively). 25-OHD levels were positively correlated with exposure to sunlight and negatively correlated with the duration of being veiled. None of the veiled women had vitamin D insufficiency, but their mean 25-OHD concentration (33.1 ± 16 ng/ml) was significantly lower than that of controls (53.9 ± 27.3 ng/ml) (p ? 0.001), and serum alkaline phosphatase (ALP) levels were higher (p < 0.01). Differences in the absolute BMD values at the spine and hip were not statistically significant, but the mean Z value at the lumbar spine was significantly lower in the veiled subjects (p < 0.05). Veiled women have low 25-OHD status, and vitamin D supplementation should strictly be advised to these women for the prevention of osteomalacia and osteoporosis.
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- 2001
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26. Hepatic endometrioma: a case report and review of the literature
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Süreyya Soyupak, Kenan Bicakci, Mehmet Inal, Önder Demirbaş, C. Özer, Erol Akgül, Mahmut Oğuz, and Çukurova Üniversitesi
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Adult ,medicine.medical_specialty ,medicine.diagnostic_test ,Extrapelvic endometriosis ,business.industry ,Liver Diseases ,General surgery ,Ultrasound ,Endometriosis ,Interventional radiology ,General Medicine ,Magnetic Resonance Imaging ,Diagnosis, Differential ,Liver neoplasms ,Diagnosis ,medicine ,Humans ,Female ,Radiology, Nuclear Medicine and imaging ,Radiology ,Tomography, X-Ray Computed ,business ,Neuroradiology - Abstract
PubMedID: 10756990 Extrapelvic endometriosis is not uncommon but hepatic endometrioma is extremely rare. Ultrasound, CT and MR features of hepatic endometrioma are discussed and the literature is reviewed in this report.
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- 2000
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27. Mobile right atrial hydatid cyst with multiorgan involvement
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Süreyya Soyupak, Mustafa Demirtaş, Caner Özer, Mehmet Kanadaşı, Mustafa Şan, Bülent Kisacikoğlu, and Çukurova Üniversitesi
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Adult ,Echinococcosis, Hepatic ,medicine.medical_specialty ,Echinococcosis, Pulmonary ,Heart Diseases ,Heart disease ,Antibodies, Helminth ,Albendazole ,Diagnosis, Differential ,Hydatid emboli ,Magnetic resonance imaging ,Echinococcosis ,parasitic diseases ,medicine ,Animals ,Humans ,Radiology, Nuclear Medicine and imaging ,Cyst ,Heart Atria ,Cardiac Surgical Procedures ,Lung ,medicine.diagnostic_test ,business.industry ,Respiratory disease ,General Medicine ,Cardiac surgery ,medicine.disease ,Echinococcus ,Surgery ,medicine.anatomical_structure ,Echocardiography ,Female ,Radiology ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Abstract
A 25-year-old woman who had hydatid cysts in her lung was referred to our clinic for the hydatid cyst in her cardiac localization. Multiple hydatid cysts of different cardiac localizations were diagnosed by two-dimensional echocardiography, confirmed by computed tomography and magnetic resonance imaging, supported by enzyme-linked immunosorbent assay (ELISA) for echinococcosis. Surgical resection was performed for the right atrial cyst and pathology confirmed the diagnosis. Oral albendazole treatment was given postoperatively. Cathet. Cardiovasc. Intervent. 49:204–207, 2000. © 2000 Wiley-Liss, Inc.
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- 2000
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28. Ultrasonographic measurement of subarachnoid space in normal term newborns
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Hacer Yapıcıoğlu Yıldızdaş, Yasar Sertdemir, Nejat Narli, Süreyya Soyupak, Ercan Tutak, Mehmet Satar, Kenan Özcan, Çukurova Üniversitesi,Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çukurova Üniversitesi,Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Anabilim Dalı, Çukurova Üniversitesi,Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik Anabilim Dalı, Narlı, Nejat, Soyupak, Süreyya, Yıldızdaş, Hacer Y., Tutak, Ercan, Özcan, Kenan, Sertdemir, Yaşar, and Satar, Mehmet
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Male ,Term Birth ,Gestational Age ,Body weight ,Correlation ,Ultrasound ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,Normal range ,Ultrasonography ,business.industry ,Body Weight ,Infant, Newborn ,Gestational age ,General Medicine ,Newborn ,Body Height ,Term (time) ,Subarachnoid space ,medicine.anatomical_structure ,Female ,business ,Nuclear medicine ,Head - Abstract
PubMedID: 16406435 This study was conducted in order to assess the normal range of subarachnoid space width in healthy term newborns. A total of 230 healthy newborns were evaluated within the first 28 days of life. Measurements were correlated with body weight, height and head circumference. Mean measurements for falx-cortex and craniocortical widths and the correlations are given in tables. Subarachnoid space widths increased as weight, height and head circumference increased and the correlation was statistically significant. © 2005 Elsevier Ireland Ltd. All rights reserved.
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- 2006
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29. Two newborn babies with generalized arterial calcification of infancy, two new mutations
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Nazan Özbarlas, Selim Büyükkurt, Mehmet Bertan Yilmaz, Ferda Özlü, Süreyya Soyupak, Sevcan Erdem, Kadri Karaer, Utku U. Güllü, Hacer Yapıcıoğlu-Yıldızdaş, and Çukurova Üniversitesi
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medicine.medical_specialty ,First year of life ,Diffuse calcification ,030204 cardiovascular system & hematology ,Generalized arterial calcification ,03 medical and health sciences ,0302 clinical medicine ,newborn ,medicine.artery ,Internal medicine ,medicine ,Humans ,Pyrophosphatases ,Vascular Calcification ,Mesenteric arteries ,idiopathic generalized arterial calcification ,Aorta ,Diphosphonates ,Phosphoric Diester Hydrolases ,business.industry ,Infant, Newborn ,Infant ,Arteries ,medicine.anatomical_structure ,Echocardiography ,030220 oncology & carcinogenesis ,Mutation ,Pediatrics, Perinatology and Child Health ,Cardiology ,Female ,business - Abstract
PubMedID: 28276217 Idiopathic generalized arterial calcification of infancy-1 (GACI-1) is a rare and potentially lethal disease characterized by diffuse calcification of large and medium-sized arteries such as aorta, renal, pulmonary, cerebral and mesenteric arteries. Here we report two new mutations in two newborn babies with GACI-1 treated with bisphosphonates, and their progress in the first year of life.
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- 2016
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30. Severe abdominal trauma involving bicycle handlebars in children
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Süreyya Soyupak, Serdar H. Iskit, Murat Alkan, Recep Tuncer, Ünal Zorludemir, Erbug Keskin, Hasan Okur, and Çukurova Üniversitesi
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Male ,medicine.medical_specialty ,Turkey ,medicine.medical_treatment ,Poison control ,severe handlebar injury ,Abdominal Injuries ,Intensive Care Units, Pediatric ,Wounds, Nonpenetrating ,law.invention ,Diagnosis, Differential ,Abdominal wall ,law ,Laparotomy ,medicine ,Humans ,Child ,Retrospective Studies ,Trauma Severity Indices ,business.industry ,Incidence ,General Medicine ,Emergency department ,Liver Laceration ,Prognosis ,medicine.disease ,Intensive care unit ,Bicycling ,Surgery ,Early Diagnosis ,medicine.anatomical_structure ,Abdominal trauma ,Blunt trauma ,Pediatrics, Perinatology and Child Health ,Emergency Medicine ,Female ,Tomography, X-Ray Computed ,business ,Follow-Up Studies - Abstract
PubMedID: 19680164 OBJECTIVES: To emphasize the severity of the underlying injury which may not be realized during the initial patient admission to the emergency department. METHODS: A retrospective case note review of children admitted to our institution with the severe abdominal injury. RESULTS: Eight children were identified with the severe abdominal injury secondary to the trauma from a bicycle handlebar that needed special care in the intensive care unit. All injuries were due to blunt trauma. The mean delay from the time of the accident to the time of presentation was 34.5 hours. All patients had an imprint of the handlebar edge on the hypochondrium. There were 3 pancreatic lacerations, 1 duodenal laceration, 1 jejunal laceration, 1 liver laceration, 1 abdominoinguinal laceration that all required open surgery, and 1 duodenal hematoma that resolved in 4 weeks follow-up period. The patients who required open surgery were evaluated with computed tomographic scans before surgery. CONCLUSIONS: Children with an imprint made by the handlebar edge on the abdominal wall or give a clear history of injuries by a bicycle handlebar should be treated with great care. Early computed tomography evaluation may help to reduce the morbidity resulting from the delay in diagnosis of injuries to the internal organs. © 2012 Lippincott Williams & Wilkins, Inc.
- Published
- 2012
31. Pediatric invasive mucormycosis cured with high dose liposomal amphotericin B
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Derya Gümürdülü, Fatih Erbey, Ibrahim Bayram, Emine Kocabaş, Süreyya Soyupak, Atila Tanyeli, and Çukurova Üniversitesi
- Subjects
Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Antifungal Agents ,Burun ,Critical Care and Intensive Care Medicine ,Solunum Sistemi ,Amphotericin B ,medicine ,Humans ,Mucormycosis ,Child ,Pulmonary mucormycosis ,Dose-Response Relationship, Drug ,Medical treatment ,business.industry ,Boğaz ,Kulak ,bacterial infections and mycoses ,medicine.disease ,Surgery ,Pediatric patient ,Treatment Outcome ,Liposomal amphotericin ,business ,medicine.drug - Abstract
Pulmoner mukormikozis medikal tedavisinin temel dayanağı amfoterisin B olup, optimal doz konusunda henüz bir fikir birliği bulunmamaktadır. Bu yazıda pulmoner mukormikozis gelişen akut lenfblastik lösemili bir olgunun 45 haftalık sürede toplam 42.55 g lipozomal amfoterisin B kullanılarak başarıyla tedavi edildiği sunulmaktadır. Tıbbi literatüre bakıldığında bu olgu çocukluk çağında en yüksek dozda lipozomal amfoterisin B’nin başarıyla kullanıldığı ilk olgudur Amphotericin B remains the mainstay medical treatment of pulmonary mucormycosis. Optimal dose is not defined. We described a case of pulmonary mucormycosis, which had been treated with 42.55 g (during to 45 weeks) liposomal amphotericin B. In medical literature this case is one of the highest doses of lyposomal amphotericin B administered to a pediatric patient.
- Published
- 2012
32. Percutaneous Transhepatic Endobiliary Drainage of Hepatic Hydatid Cyst with Rupture into the Biliary System: An Unusual Route for Drainage
- Author
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Mehmet Inal, Süreyya Soyupak, Hüseyin Ezici, Erol Akgül, and Çukurova Üniversitesi
- Subjects
Echinococcosis, Hepatic ,medicine.medical_specialty ,Percutaneous ,Fistula ,Cholestasis ,parasitic diseases ,medicine ,Humans ,Bile ducts ,Radiology, Nuclear Medicine and imaging ,Cyst ,Abscess ,Rupture ,Rupture, Spontaneous ,Percutaneous drainage ,business.industry ,Middle Aged ,Jaundice ,medicine.disease ,Surgery ,Treatment ,Hydatid cyst ,Biliary tract ,Drainage ,Female ,Radiology ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Complication - Abstract
PubMedID: 12170351 The most common and serious complication of hydatid cyst of the liver is rupture into the biliary tract causing obstructive jaundice, cholangitis and abscess, The traditional treatment of biliary-cystic fistula is surgery and recently endoscopic sphincterotomy. We report a case of complex heterogeneous cyst rupture into the biliary tract causing biliary obstruction in which the obstruction and cyst were treated successfully by percutaneous transhepatic endobiliary drainage, Our case is the second report of percutaneous transbiliary internal drainage of hydatid cyst with rupture into the biliary duct in which the puncture and drainage were not performed through the cyst cavity.
- Published
- 2002
- Full Text
- View/download PDF
33. Portal venous diameter in children: Normal limits according to age, weight and height
- Author
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Süreyya Soyupak, Gulsah Seydaoglu, Mehmet Inal, Aylin Gunesli, Medih Çeliktaş, Figen Binokay, and Çukurova Üniversitesi
- Subjects
Male ,medicine.medical_specialty ,Vena porta ,Adolescent ,Portal vein ,Body size ,Port (medical) ,Reference Values ,Ultrasound ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Child ,Ultrasonography ,Pediatric ,business.industry ,Body Weight ,Age Factors ,Infant ,General Medicine ,Normal limit ,Body Height ,Surgery ,Child, Preschool ,Female ,business ,Nuclear medicine - Abstract
Purpose: To establish the normal limits of portal vein diameter according to age, height and weight. Materials and methods: One hundred and sixty-eight healthy children, ages ranging from 1 month to 15 years were examined by ultrasound. Portal vein diameters at hepatic port, weight and height were recorded. Results: A range of normal limits for portal veneous diameter according to age, weight and height are obtained and presented in tables. Conclusion: Knowing the normals for portal venous diameter in every age group in children is mandatory in differentiating disease. The tables according to age, weight and height will definitely be helpful in the work-up process. © 2009 Elsevier Ireland Ltd.
- Published
- 2010
34. Coexistence of non-hodgkin's lymphoma and cyst hydatid disease and successful medical treatment
- Author
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Süreyya Soyupak, Ibrahim Bayram, Atila Tanyeli, Fatih Erbey, and Çukurova Üniversitesi
- Subjects
Male ,medicine.medical_specialty ,Pathology ,Medical treatment ,business.industry ,Lymphoma, Non-Hodgkin ,Hematology ,Disease ,medicine.disease ,Echinococcosis ,Oncology ,Pediatrics, Perinatology and Child Health ,Humans ,Medicine ,Hodgkin lymphoma ,Cyst ,Radiology ,Child ,business - Abstract
[No abstract available]
- Published
- 2010
35. The effect of retroperitoneal fat tissue thickness on testicular venous drainage
- Author
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I.A. Aridogan, Mehmet Inal, Süreyya Soyupak, Medih Çeliktaş, Kairgueldy Aikimbaev, and Çukurova Üniversitesi
- Subjects
Male ,medicine.medical_specialty ,Intra-Abdominal Fat ,Urology ,Varicocele ,Adipose tissue ,Body Mass Index ,Veins ,Testis ,medicine ,Humans ,Venous drainage ,Obesity ,Aged ,business.industry ,Middle Aged ,medicine.disease ,Radiography ,Bromhexine ,Regional Blood Flow ,Radiology ,business ,Retroperitoneum - Abstract
Introduction: We evaluated a possible effect of the amount of retroperitoneal fat tissue on testicular venous drainage to shed light on the mechanism of varicocele occurrence. Patients andMethods: A total of 132 patients with no fertility complaints were included in this study. Retroperitoneal fat thickness (RPFT) was measured during abdominal computed tomography examinations. According to the calculated body mass index (BMI), patients were categorized as normal, overweight or obese using National Institutes of Health criteria. Relationships were sought between RPFT, BMI and testicular vein-pampiniform plexus diameters measured with ultrasonography on both sides. Results: Left and right testicular vein maximum diameters were significantly larger in obese patients compared with normal and overweight men (p = 0.01 and p = 0.003, respectively). In accordance with this, the left and right pampiniform plexus diameters were larger in the obese group than in the normal and overweight groups (p = 0.004 and p = 0.006, respectively). There was a moderate but significant correlation between the right testicular vein maximum diameter and mean RPFT (p = 0.003). The relationship between bilateral pampiniform plexus diameters and retroperitoneal fat distribution was stronger and significant (p = 0.0001). Correlation analysis revealed a significant relationship between BMI and retroperitoneal fat distribution (R = 0.53, p = 0.0001). Conclusions: The amount of retroperitoneal fat, which is related to BMI, could be a contributing factor in the etiology of right varicocele.
- Published
- 2009
36. Crocodile Tears and Dandy-Walker Syndrome in Cervico-oculo-acoustic Syndrome
- Author
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Caner Özer, Gühanim Haciyakupoglu, Şakir Altunbaşak, Süreyya Soyupak, Aysel Pelit, and Çukurova Üniversitesi
- Subjects
Adolescent ,Klippel–Feil syndrome ,Deafness ,Duane Retraction Syndrome ,Dandy–Walker syndrome ,Humans ,Medicine ,Crocodile tears syndrome ,Crocodile tears ,Lacrimal Apparatus Diseases ,business.industry ,Dysostosis ,General Medicine ,Anatomy ,medicine.disease ,Magnetic Resonance Imaging ,Ophthalmology ,Klippel-Feil deformity ,Klippel-Feil Syndrome ,Tears ,Pediatrics, Perinatology and Child Health ,Female ,Congenital disease ,Dandy-Walker Syndrome ,Tomography, X-Ray Computed ,business ,Dandy-Walker malformation - Abstract
PubMedID: 10505838 [No abstract available]
- Published
- 1999
- Full Text
- View/download PDF
37. Determining the level of the durai sac tip: Magnetic resonance imaging in an adult population
- Author
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Figen Binokay, Erol Aksungur, Yasar Sertdemir, Kenan Bicakci, Erol Akgül, Süreyya Soyupak, and Çukurova Üniversitesi
- Subjects
Adult ,Male ,Adolescent ,Dura mater ,Adult population ,030218 nuclear medicine & medical imaging ,Lumbosacral region ,03 medical and health sciences ,Sex Factors ,0302 clinical medicine ,Durai sac termination ,Magnetic resonance imaging ,Reference Values ,Female patient ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,dural sac termination ,Aged ,Retrospective Studies ,Aged, 80 and over ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Age Factors ,Lumbosacral Region ,General Medicine ,Anatomy ,Middle Aged ,Sagittal plane ,Vertebral body ,Intervertebral disk ,medicine.anatomical_structure ,Lumbar spine ,030220 oncology & carcinogenesis ,Female ,Normal population ,Dura Mater ,Nuclear medicine ,business - Abstract
Purpose: To determine the variation in the location of the dural sac (DS) in a living adult population and to correlate this position with age and sex. Material and Methods: T2-weighted, midline, sagittal, spin-echo magnetic resonance imaging (MRI) studies of 743 patients were assessed to identify the tip of the DS. This location was recorded in relation to the upper, middle, or lower third of the adjacent vertebral body or the adjacent intervertebral disk. Results: Frequency distribution for levels of termination of the DS on MRI demonstrated that the end of the DS was usually located at the upper one-third of S2 (25.2%). The mean level in females was also the upper one-third of S2 (26.5%) and in males the lower one-third of S2 (24.1%). The overall mean DS position was mostly at the upper one-third of S2. No significant differences in DS position were seen between male and female patients or with increasing age. Conclusion: It is important to know the possible range for the termination level of the DS when performing caudal anesthesia and craniospinal irradiation in some clinical situations. The distribution of DS location in a large adult population was shown to range from the L5-S1 intervertebral disk to the upper third of S3 vertebrae.
- Published
- 2006
38. Risk of developing fibroadenoma with the use of cyclosporine A in renal transplant recipients
- Author
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Erkan Demir, Süreyya Soyupak, Mustafa Balal, Yasar Sertdemir, Erol Akgül, Figen Binokay, Saime Paydas, and Çukurova Üniversitesi
- Subjects
Nephrology ,Adult ,medicine.medical_specialty ,Combination therapy ,medicine.medical_treatment ,Urinary system ,Urology ,Breast Neoplasms ,Critical Care and Intensive Care Medicine ,Risk Assessment ,Drug Administration Schedule ,Renal Dialysis ,Transplantation Immunology ,Internal medicine ,medicine ,Humans ,skin and connective tissue diseases ,Dialysis ,Ultrasonography ,Dose-Response Relationship, Drug ,business.industry ,Incidence ,Biopsy, Needle ,Renal transplantation ,Immunosuppression ,General Medicine ,medicine.disease ,Fibroadenoma ,Immunohistochemistry ,Kidney Transplantation ,Surgery ,body regions ,Transplantation ,Cross-Sectional Studies ,Chronic renal failure (CRF) ,Cyclosporine ,Kidney Failure, Chronic ,Female ,Cyclosporine A (Cyc A) ,business ,Immunosuppressive Agents ,Kidney disease ,Follow-Up Studies - Abstract
PubMedID: 16350824 To investigate the effect of cyclosporine A (Cyc A) on the development of fibroadenomas, 30 renal transplant patients and 20 chronic renal failure patients on dialysis were breast examined with ultrasonography and/or mammography. Of the renal transplant patients, 17 were receiving Cyc A-based combination therapy for immunosuppression. All patients were female with the age range of 29.7±9.2 years in the transplant group and 33.95±9.91 in the dialysis group. Eight of the 17 patients receiving Cyc A had fibroadenomas, 5 of them having bilateral lesions. None of the other patients, those on dialysis and on non-Cyc A combination therapy had fibroadenomas. A significant difference for fibroadenoma incidence in patients receiving Cyc A combination immunosuppression was found. Copyright © 2005 Taylor & Francis Inc.
- Published
- 2005
39. A homozygous BMPR1B mutation causes a new subtype of acromesomelic chondrodysplasia with genital anomalies
- Author
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Erol Akgül, Süreyya Soyupak, Georg C. Schwabe, D Karahan, Deniz Taştemir, Seval Türkmen, Stefan Mundlos, Katarina Lehmann, Osman Demirhan, and Çukurova Üniversitesi
- Subjects
medicine.medical_specialty ,Adolescent ,Limb Deformities, Congenital ,Short Report ,GDF5 ,Biology ,medicine.disease_cause ,Growth Differentiation Factor 5 ,Internal medicine ,Genetics ,medicine ,Missense mutation ,Humans ,Ovarian Diseases ,Genetics (clinical) ,Bone Morphogenetic Protein Receptors, Type I ,Mutation ,Models, Genetic ,Brachydactyly ,Homozygote ,Aplasia ,medicine.disease ,Osteochondrodysplasia ,Hypoplasia ,BMPR1B ,Pedigree ,Endocrinology ,Phenotype ,Bone Morphogenetic Proteins ,Female ,Sequence Analysis - Abstract
PubMedID: 15805157 We present a patient with acromesomelic chondrodysplasia and genital anomalies caused by a novel homozygous mutation in BMPR1B, the gene coding for bone morphogenetic protein receptor 1B. The 16 year old girl, the offspring of a multiconsanguinous family, showed a severe form of limb malformation consisting of aplasia of the fibula, severe brachydactyly, ulnar deviation of the hands, and fusion of carpal/tarsal bones. In addition, she presented with hypoplasia of the uterus and ovarian dysfunction resulting in hypergonadotrophic hypogonadism. Mutation analysis of BMPR1B revealed a homozygous 8 bp deletion (del359-366). This mutation is expected to result in a loss of function and is thus different from the heterozygous missense mutations in BMPR1B recently shown to cause brachydactyly type A2 through a dominant negative effect. The patient's skeletal phenotype shows an overlap with the clinical spectrum of the acromesomelic chondrodysplasias of the Grebe, Hunter-Thompson, and DuPan types caused by homozygous mutations in the gene coding for growth differentiation factor 5 (GDF5) which is a high-affinity ligand to BMPR1B. However, the phenotype described here differs from GDF5 associated chondrodysplasias because of the additional presence of genital anomalies and the distinct limb phenotype.
- Published
- 2005
40. Metastatic thymoma as a retrovesical mass
- Author
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Süreyya Soyupak, Andoğan Ia, Nihat Satar, Tansuğ Z, Bülent Soyupak, Handan Zeren, and Çukurova Üniversitesi
- Subjects
Adult ,Male ,Pathology ,medicine.medical_specialty ,Metastatic lesions ,Thymoma ,Retrovesical mass ,Urinary Bladder ,Metastasis ,Humans ,Medicine ,business.industry ,Advanced stage ,fungi ,food and beverages ,Thymus Neoplasms ,General Medicine ,Space-occupying lesion ,medicine.disease ,Tumor progression ,Abdominal Neoplasms ,Surgery ,Differential diagnosis ,business - Abstract
PubMedID: 15790214 Retrovesical masses can be of various histopathological origin, most often prostatic. Primary tumours as well as metastatic lesions should be considered in the differential diagnosis. Metastatic thymoma, as presented in this case report, can be an extremely rare cause of retrovesical space occupying lesion.
- Published
- 2005
41. Fucosidosis with hypothyroidism: a case report
- Author
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Neslihan, Onenli-Mungan, Güler, Ozer, Sakir, Altunbaşak, Guy, Besley, Bilgin, Yüksel, Ali Kemal, Topaloğlu, and Süreyya, Soyupak
- Subjects
Fucosidosis ,Male ,Radiography ,Hypothyroidism ,Brain ,Dysostoses ,Humans ,Infant ,Magnetic Resonance Imaging ,Bone and Bones - Abstract
Fucosidosis is a rare, autosomal recessive lysosomal storage disorder caused by a severe deficiency of alpha-L-fucosidase. Here we present a 27-month-old male who was referred to us for evaluation of developmental delay, which was first detected at age six months. His past medical history was also remarkable for recurrent pulmonary infections and myoclonic seiures. His family history revealed that he was the first living child from a consanguineous marriage. He had a younger sister who died at five months of age from pneumonia who had facial resemblance to the proband, developmental delay and a congenital heart defect. Physical examination revealed length: 81 cm (25-50p), weight: 10.2 kg (25-50p), and head circumference: 49 cm (50-75p). He had a coarse face, hepatomegaly and generalized spasticity. His initial laboratory examination revealed negative urine screening column chromatography for mucopolysaccharidosis. His X-ray findings were consistent with mild form of dysostosis multiplex. Based on clinical and laboratory features, fucosidosis was suspected. Fucosidase enzyme activity was zero. In addition to fucosidosis, thyroid function tests indicated primary hypothyroidism. This is, to the best of our knowledge, the fourth case of fucosidosis diagnosed in Turkey.
- Published
- 2004
42. The prevalence and variations of inferior right heratic veins on contrast-enchanced helical CT scanning
- Author
-
Figen Binokay, Süreyya Soyupak, Medih Çeliktaş, Mehmet Inal, Kairgueldy Aikimbaev, Erol Akgül, and Çukurova Üniversitesi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Helical computed tomography ,Inferior right ,Contrast Media ,Vena Cava, Inferior ,Hepatic Veins ,liver ,Inferior vena cava ,Lesion ,Prevalence ,Humans ,Medicine ,Right hepatic lobe ,Radiology, Nuclear Medicine and imaging ,Computed tomography, Helical ,inferior right ,Child ,Aged ,Aged, 80 and over ,Hepatic vein, Inferior right ,Chi-Square Distribution ,business.industry ,Infant ,computed tomography ,General Medicine ,Middle Aged ,Helical ct ,medicine.vein ,Child, Preschool ,hepatic vein ,Hepatic veins ,cardiovascular system ,Female ,Radiology ,medicine.symptom ,Tomography, X-Ray Computed ,business ,Chi-squared distribution ,helical - Abstract
WOS: 000224728900008 PubMed ID: 15380849 Purpose: To present the prevalence and variations of inferior right hepatic veins (IRHVs) on contrast-enhanced helical computed tomography (CEHCT) scans. Materials and methods: The routine abdominal CEHCT scans of 349 patients were reviewed. Three hundred and eight patients (88.2%) were included in the study. Of the 349 patients, 41 (11.8%) were excluded from the study because of improper opacification of hepatic veins and right hepatic lobe lesions which made difficult the optimal visualization and assessment of IRHVs. The mean age of 308 patients was 43 years (range 3-97 years). One hundred and forty-three patients (46.4%) were men and 165 (53.6%) women. Scans were examined whether the IRHVs were demonstrated or not and classified according to their numbers, levels, diameters, and joinings to inferior vena cava (IVC). Results: Of the 308 patients, 65 (21.1%) had one or two IRHVs. Fifty-four patients (83.1%) had only one IRHV and 11 (16.9%) patients had two. More than two IRHVs were not seen in any patient. Eight (72.7%) of 11 double IRHVs joined the IVC at the same level and others (27.3%) did not. There was no truncal opening to the IVC. In five patients (7.7%) the IRHV were large (greater than or equal to0.5 cm). Conclusion: The presence of IRHVs is common and routine CEHCT scanning is efficacious in assessment of IRHVs. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
- Published
- 2004
43. Type 2 diabetes mellitus and osteopenia: is there an association?
- Author
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Sinan Kirim, Murat Sert, Tamer Tetiker, Süreyya Soyupak, Abdullah Canataroglu, Mustafa Koçak, Çukurova, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Anabilim Dalı, Çukurova, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Anabilim Dalı, Sert, Murat, Tetiker, Tamer, Kirim, Sinan, Soyupak, Süreyya, Canataroğlu, Abdullah, and Koçak, Mehmet
- Subjects
musculoskeletal diseases ,Adult ,Male ,medicine.medical_specialty ,Bone density ,Endocrinology, Diabetes and Metabolism ,Osteoporosis ,Lumbar vertebrae ,Endocrinology ,Bone Density ,Risk Factors ,Diabetes mellitus ,Internal medicine ,Type 2 diabetes mellitus ,Bone mineral density ,Internal Medicine ,medicine ,Humans ,Femur ,Prospective cohort study ,Femoral neck ,business.industry ,Type 2 Diabetes Mellitus ,General Medicine ,Middle Aged ,musculoskeletal system ,medicine.disease ,Surgery ,Osteopenia ,Bone Diseases, Metabolic ,medicine.anatomical_structure ,Diabetes Mellitus, Type 2 ,Body Constitution ,Female ,business - Abstract
PubMedID: 12861410 We report the results of bone mineral density (BMD) measurements in type 2 diabetic patients, in comparison to healthy controls. In this prospective study, a total of 277 subjects (aged 30-60 years) with type 2 diabetes mellitus, outpatients at the Cukurova Medical School Hospital, were evaluated for BMD at L1-L4 lumbar vertebrae and at the femur (neck, trochanter, Ward's triangle and total) by DEXA (dual energy X-ray absorptiometry). The patients' diabetes duration, treatment, glycemic control and chronic diabetic complications were recorded, and these data were evaluated for any relationship in respect to the BMD measurements. BMD results of the diabetic patients were compared with those of 262 healthy non-diabetic control subjects living in the same geographic region. BMD was found to be increased at the femoral neck among diabetic women and men aged 51-60 years. However, BMD values at lumbar regions of diabetic men where lower than control in all age group. There was no difference in values of BMD for both genders in the other regions. Type 2 diabetic patients may have lower, similar or higher BMD measurements at different ages and anatomic regions, so each patient should be evaluated individually. Further studies are needed to make a conclusion on this issue.
- Published
- 2003
44. Primary and metastatic rhabdomyosarcoma in the breast: Report of two pediatric cases
- Author
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Mehmet Inal, Erol Akgül, Süreyya Soyupak, Medih Çeliktaş, Figen Binokay, Erol Aksungur, and Çukurova Üniversitesi
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,Primary and secondary ,Adolescent ,Breast imaging ,Childhood malignancy ,Mammary gland ,Breast Neoplasms ,Breast rhabdomyosarcoma ,Metastasis ,Mastectomy, Modified Radical ,medicine ,Humans ,Rhabdomyosarcoma, Embryonal ,Radiology, Nuclear Medicine and imaging ,Child ,Rhabdomyosarcoma ,Rhabdomyosarcoma, Alveolar ,Pediatric ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,General Medicine ,medicine.disease ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Breast Rhabdomyosarcoma ,Axillary Artery ,Female ,Sarcoma ,Radiology ,Tomography, X-Ray Computed ,business ,human activities - Abstract
PubMedID: 14652147 Rhabdomyosarcoma (RMS) is a common childhood malignancy which can rarely be located in the breast. Here, we report two pediatric cases of breast RMS, one primary, the other secondary involvement. Primary one is alveolar, and the other embryonal subtype. Imaging findings with ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI) and a thorough review of literature are presented. © 2003 Elsevier Science Ireland Ltd. All rights reserved.
- Published
- 2003
45. A case of rhabdomyosarcoma with widespread metastasis
- Author
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Fatih Erbey, İbrahim Bayram, Atilla Tanyeli, Oğuz Canan, İlgen Şaşmaz, Bülent Antmen, Süreyya Soyupak, Nurdan Tunalı, Yurdanur Kılınç, and Çukurova Üniversitesi
- Subjects
Genel ve Dahili Tıp - Abstract
Dokuz yaşında erkek hasta, bir ay içinde beş kilogram zayıflama ve kuru öksürük şikayetleri ile başvurdu. Olgunun fizik incelemesinde, akciğerde solunum sesleri azalmış, servikal, sol aksiller, sağ inguinal bölgede çok sayıda ve çeşitli boyutlarda lenfadenopati ve peniste kitle saptandı. Yapılan tetkiklerde mediastende, akciğerde (parankiminde ve plevrada), batında (yaygın olarak ve perineye kadar uzanan) değişik boyutlarda, en büyüklerinin çapı 5 cm'e ulaşan lobule konturlu düşük dansiteli yumuşak doku kitleleri izlenmekteydi. Olgudan alman biyopsi sonucunda embrional rhabdomyosarkom tanısı kondu. Tedavi olarak Vinkristin, İfosfamid ve Etoposid uygulandı. Olgu ikinci ayında yapılan değerlendirmede remisyona girdiği tespit edildi. Halen 14. ayda ve tedavisi devam etmektedir. A 9 year-old-boy was admitted to hospital with complaints of cough and weight loss. Physical examination revealed findings of decreased respiration and multiple lymphadenopathy in cervical, left axiller and right inguinal regions. He had a tumor mass on his penis. Computed tomography showed that in the lung (paranchima and pleura), mediastinal and abdominal soft tissue masses were present having diameters between 1 and 5 cm. Biopsy specimen revealed embryonal rhabdomyosarcoma. He was administered Vincristine, Ifosphamide and Etoposide treatment. He is currently alive and healthy at his 14th month of follow-up.
- Published
- 2003
46. Intraventricular streptokinase for the treatment of posthaemorrhagic hydrocephalus of preterm
- Author
-
Nejat Narli, Süreyya Soyupak, Şakir Altunbaşak, Hacer Yapıcıoğlu, Mehmet Satar, and Çukurova Üniversitesi
- Subjects
Male ,medicine.medical_specialty ,congenital, hereditary, and neonatal diseases and abnormalities ,Turkey ,Streptokinase ,Posthaemorrhagic hydrocephalus ,Gestational Age ,Fibrinolytic Agents ,Preterm ,Physiology (medical) ,medicine ,Ventriculitis ,Humans ,Cerebral Hemorrhage ,Injections, Intraventricular ,Retrospective Studies ,Vascular disease ,business.industry ,Infant, Newborn ,General Medicine ,medicine.disease ,Ventriculoperitoneal shunt ,Hydrocephalus ,Surgery ,Shunt (medical) ,nervous system diseases ,Neurology ,Premature birth ,Case-Control Studies ,Anesthesia ,Apgar Score ,Intraventricular streptokinase ,Female ,Neurology (clinical) ,Complication ,business ,Meningitis ,Infant, Premature ,medicine.drug - Abstract
PubMedID: 12763331 Posthaemorrhagic hydrocephalus following intraventricular haemorrhage is still one of the most serious complications of premature birth. Small premature babies are not suitable for shunt surgery because of high cerebrospinal fluid protein and risk of obstruction. For this reason there is a great need for alternative approaches for treatment of posthaemorrhagic hydrocephalus. The objective of this study was to investigate if intraventricular streptokinase treatment reduces the need for ventriculoperitoneal shunt in posthaemorrhagic hydrocephalus. A case-control trial was carried out in 12 premature babies with posthaemorrhagic hydrocephalus. Six of them were treated with intraventricular streptokinase and 6 premature babies were in the control group. While 5 babies in the study group needed ventriculoperitoneal shunt, 3 of the control patients needed shunt surgery. There were no rebleeding, ventriculitis or meningitis in either groups. In conclusion on the basis of our results we do not recommend routine use of intraventricular streptokinase in posthaemorrhagic hydrocephalus. © 2003 Elsevier Science Ltd. All rights reserved.
- Published
- 2003
47. Comparison of direct radionuclide cystography and voiding direct cystography in the detection of vesicoureteral reflux
- Author
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Aysun Karabay Bayazit, Süreyya Soyupak, Zeynep Yapar, Ali Anarat, Mustafa Kibar, Aytül Noyan, Aysun Sukan, and Çukurova Üniversitesi
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,media_common.quotation_subject ,Urology ,Urination ,Scintigraphy ,Sensitivity and Specificity ,Vesicoureteral reflux ,Cystography ,Ureter ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Radionuclide cystography ,Child ,Radionuclide Imaging ,Sodium Pertechnetate Tc 99m ,media_common ,Vesico-Ureteral Reflux ,Voiding cystourethrography ,medicine.diagnostic_test ,business.industry ,Significant difference ,Infant ,Reproducibility of Results ,General Medicine ,medicine.disease ,medicine.anatomical_structure ,Dimercaptosuccinic acid ,Child, Preschool ,Technetium Tc 99m Dimercaptosuccinic Acid ,Female ,Continuous recording ,Radiology ,Radiopharmaceuticals ,business ,Vesicoureteric reflux ,medicine.drug - Abstract
PubMedID: 14651353 Purpose: The aim of this study is to compare the results of direct radionuclide cystography (DRNC) and voiding cystourethrography (VCUG) in a group of children with a high suspicion of vesicoureteral reflux (VUR). Methods: For this purpose, 25 children were studied with both VCUG and DRNC. Among 50 ureter units able to be compared 39 ureter units did not show any VUR on either study. Eleven ureter units (10 children) had VUR either on one study or on both (VCUG and DRNC). In the children who had VUR on either study, a dimercaptosuccinic acid scintigraphy (DMSA) was performed to determine their cortical function. Results: We identified the following four patterns: 1) Five ureter units (five children) read positive on DRNC who were negative on VCUG and four of these children had positive findings on DMSA; 2) Four ureter units (four children) read positive on VCUG who were negative on DRNC, and two of them had positive findings on DMSA; 3) Two ureters (one child) read positive in both studies and also had abnormal DMSA findings; 4) Thirty-nine ureter units read as negative on both studies. Conclusion: Although the results of these two methods did not show a significant difference, DRNC offers a high sensitivity in the younger age group whereas VCUG seems to be more sensitive in the older age group. DRNC also offers continuous recording during the study, ease of assessment and lower radiation dose to the gonads, which makes it a preferable method for the initial diagnosis and follow-up of VUR.
- Published
- 2003
48. Fluoroscopically guided endoluminal balloon dilatation of esophageal stricture due to epidermolysis bullosa dystrophica
- Author
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Erol Akgül, Erol Aksungur, Mehmet Inal, Alper Akınoğlu, Süreyya Soyupak, and Çukurova Üniversitesi
- Subjects
Adult ,medicine.medical_specialty ,Balloon dilatation ,Perforation (oil well) ,Balloon ,Catheterization ,Speech and Hearing ,Esophagus ,Internal medicine ,medicine ,otorhinolaryngologic diseases ,Bougienage ,Humans ,Epidermolysis bullosa ,integumentary system ,business.industry ,Gastroenterology ,Epidermolysis bullosa dystrophica ,Hepatology ,medicine.disease ,Dysphagia ,digestive system diseases ,Surgery ,Deglutition ,Epidermolysis Bullosa Dystrophica ,Treatment ,medicine.anatomical_structure ,Otorhinolaryngology ,Fluoroscopy ,Esophageal stricture ,Esophageal Stenosis ,Female ,medicine.symptom ,business ,Deglutition Disorders ,Stricture - Abstract
PubMedID: 12140654 Epidermolysis bullosa dystrophica is a hereditary blistering disorder in which the mucosal surface of the esophagus is frequently involved in addition to skin. Blister formation after minor trauma leads to erosions, ulcerations, scarring, and stricture formation in the esophagus and causes dysphagia. There is no definitive medical management for esophageal lesions. Colonic interposition has considerable mortality and morbidity, while surgical or endoscopic bougienage is not recommended because it causes further trauma to the esophagus, which accelerates stricture formation, and has a high risk of perforation. Herein we report a case of esophageal stricture successfully treated with repeated balloon dilatations.
- Published
- 2002
49. Portal venous variations: Prevalence with contrast-enhanced helical CT
- Author
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Erol Aksungur, Mahmut Oğuz, Figen Binokay, Süreyya Soyupak, Erol Akgül, Mehmet Inal, and Çukurova Üniversitesi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Abdominal ct ,Portal venous system ,Contrast Media ,Helical CT, contrast enhancement ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Child ,Aged ,Retrospective Studies ,Retrospective review ,Radiological and Ultrasound Technology ,Left portal vein ,business.industry ,Portal Vein ,Infant ,General Medicine ,Middle Aged ,Image Enhancement ,Helical ct ,Portal venous variations, anatomy ,Child, Preschool ,Right posterior ,Main portal vein ,Female ,Radiology ,business ,Tomography, X-Ray Computed ,Right anterior - Abstract
WOS: 000176515100013 PubMed ID: 12100330 Purpose: To review the distribution of intrahepatic portal venous branching in order to determine the prevalence of variations. Material and Methods: We made a retrospective review of 655 contrast-enhanced helical CT (CECT) images of patients referred to our department for upper abdominal CT examination during an 8-month period. Of the 655 patients, 70 were eliminated from the study because of improper opacification of the portal venous system. Variations of portal venous branching in the remaining 585 patients were classified. Results: Of 585 patients, 504 (86.2%) had classical bifurcation of the main portal vein (MPV); 72 (12.3%) had a trifurcation of the MPV, 5 (0.9%) had a right anterior segmental branch originating from the left portal vein (LPV), 2 (0.3%) had an LPV originating from the right anterior segmental branch and 2 (0.3%) had a right posterior segmental branch arising from the MPV. Conclusion: Variations of portal venous branching are common and helical CT is efficacious in identifying these variations.
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- 2002
50. Percutaneous biliary drainage: An alternative treatment for biliary fascioliasis
- Author
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Süreyya Soyupak, Mehmet Inal, Erol Akgül, F. Doran, A. Uğuz, Nazan Okur, and Çukurova Üniversitesi
- Subjects
Fascioliasis ,medicine.medical_specialty ,Percutaneous ,Biliary Tract Diseases ,Urology ,medicine.medical_treatment ,Helminthiasis ,Bile duct, sonography, computed tomography ,Radiography, Interventional ,Percutaneous transhepatic cholangiography ,Fascioliasis, disease ,Gastroenterology ,Catheterization ,Liver, cholangiography ,Diagnosis, Differential ,Cholangiography ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Biliary Tract ,Therapeutic Irrigation ,Povidone-Iodine ,Aged ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Hepatobiliary disease ,Metastatic liver disease ,General Medicine ,Hepatology ,medicine.disease ,Liver ,Biliary tract ,Anti-Infective Agents, Local ,Drainage ,Female ,medicine.symptom ,business - Abstract
PubMedID: 12172996 Fascioliasis initially involves the liver parenchyma and then the biliary ducts. The disease can mimic most hepatobiliary diseases at different stages of involvement. We report a case in which the final diagnosis was reached by microscopic demonstration of Fasciola hepatica eggs in bile obtained by percutaneous transhepatic biliary drainage. Computed tomographic findings that were misinterpreted as metastatic liver disease are presented, and the roles of percutaneous transhepatic cholangiography and biliary drainage are discussed.
- Published
- 2002
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