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Made available in DSpace on 2018-12-11T17:27:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-01-01. Added 1 bitstream(s) on 2021-07-15T15:03:57Z : No. of bitstreams: 1 S0365-05962016000100049.pdf: 319668 bytes, checksum: 5210661e92fd56dd2bdededc908c4a4f (MD5) The last Brazilian guidelines on melanoma were published in 2002. Development in diagnosis and treatment made updating necessary. The coordinators elaborated ten clinical questions, based on PICO system. A Medline search, according to specific MeSH terms for each of the 10 questions was performed and articles selected were classified from A to D according to level of scientific evidence. Based on the results, recommendations were defined and classified according to scientific strength. The present Guidelines were divided in two parts for editorial and publication reasons. In this second part, the following clinical questions were answered: 1) which patients with primary cutaneous melanoma benefit from sentinel lymph node biopsy? 2) Follow-up with body mapping is indicated for which patients? 3) Is preventive excision of acral nevi beneficious to patients? 4) Is preventive excision of giant congenital nevi beneficious to patients? 5) How should stages 0 and I primary cutaneous melanoma patients be followed?. Hospital Israelita Albert Einstein Hospital Alemão Oswaldo Cruz-São Paulo Oncoderma-São Paulo Universidade Federal do Rio Grande do Sul (UFRGS) Hospital de Clínicas de Porto Alegre Departamento de Câncer de Pele A. C. Camargo Cancer Center Universidade Federal de Minas Gerais (UFMG) Universidade Estácio de Sá (UNESA) Hospital Ipiranga Universidade Estadual do Pará (UEPA) Instituto do Câncer do Estado de São Paulo (ICESP) Universidade Estadual Paulista “Júlio de Mesquita Filho”(UNESP) Universidade Estadual Paulista “Júlio de Mesquita Filho”(UNESP)

Melanomas can arise either de novo (70%) or from pre-existing melanocytic lesions (30%). Of the latter, most cases arise at the dermoepidermal junction from small congenital or acquired non-blue nevi while only a few arise from blue nevi, notably the cellular subtype and less commonly the common (dendritic) type. Melanomas that arise from blue nevi usually occur on the scalp with greater frequency, as in the case described. Although previous studies have discussed melanoma arising from giant congenital blue nevi, few have discussed those arising from intermediate blue nevi. We present a case of a 52-yearold man with melanoma on the scalp evolving from an intermediate congenital common blue nevus.

Made available in DSpace on 2018-12-11T17:26:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-11-01. Added 1 bitstream(s) on 2019-10-09T18:32:22Z : No. of bitstreams: 1 S0365-05962015000600851.pdf: 302041 bytes, checksum: d128a7372fef4f69a247300d50e4671a (MD5) The last Brazilian guidelines on melanoma were published in 2002. Development in diagnosis and treatment made updating necessary. The coordinators elaborated ten clinical questions, based on PICO system. A Medline search, according to specific MeSH terms for each of the 10 questions was performed and articles selected were classified from A to D according to level of scientific evidence. Based on the results, recommendations were defined and classified according to scientific strength. The present Guidelines were divided in two parts for editorial and publication reasons. In the first part, the following clinical questions were answered: 1) The use of dermoscopy for diagnosis of primary cutaneous melanoma brings benefits for patients when compared with clinical examination? 2) Does dermoscopy favor diagnosis of nail apparatus melanoma? 3) Is there a prognostic difference when incisional or excisional biopsies are used? 4) Does revision by a pathologist trained in melanoma contribute to diagnosis and treatment of primary cutaneous melanoma? What margins should be used to treat lentigo maligna melanoma and melanoma in situ?. Hospital Israelita Albert Einstein Hospital Alemão Oswaldo Cruz Oncoderma Hospital Ipiranga Universidade Estadual do Pará (UEPA) Instituto do Câncer do Estado de São Paulo (ICESP) Departamento de Câncer de Pele A. C. Camargo Cancer Center Universidade Federal de Minas Gerais (UFMG) Universidade Federal do Rio Grande do Sul (UFRGS) Hospital de Clínicas de Porto Alegre Universidade Estácio de Sá (UNESA) Universidade Estadual Paulista ‘Júlio de Mesquita Filho’ (UNESP) Universidade Estadual Paulista ‘Júlio de Mesquita Filho’ (UNESP)