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8. Chicken meat allergy in children: Complex sensitization profiles with newly described allergen candidates.

Author

Guiddir, T., Sénéchal, H., Selva, M. A., Couderc, R., Swoboda, I., Hilger, C., Kuehn, A., Chantran, Y., Yen‐Nicolaÿ, S., Vrai, T., Ruellou, G., Baudin, B., Poncet, P., and Nemni, A.

Subjects
*FOOD allergy, *CHICKEN as food, *FOOD of animal origin, *MUSCLE proteins, *PHOSPHOGLYCERATE kinase
Abstract

This document summarizes the findings of a study on chicken meat allergy (ChMA) in children. The study found that the sensitization profiles of the children varied greatly and did not necessarily correspond to the severity of their symptoms. The researchers identified 25 potential allergens in chicken meat that could be studied further. The document acknowledges the contributions of different individuals and states that there are no conflicts of interest. [Extracted from the article]

Published
2024
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12. Allergie à la viande de poulet, analyse clinique et allergomique

Author

Guiddir, T., primary, Sénéchal, H., additional, Selva, M.A., additional, Couderc, R., additional, Swoboda, I., additional, Hilger, C., additional, Kuehn, A., additional, Chantran, Y., additional, Nicolaÿ, S., additional, Vrai, T., additional, Ruellou, G., additional, Baudin, B., additional, Poncet, P., additional, and Nemni, A., additional

Published
2023
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14. Gibberellin-regulated proteins: Emergent allergens

Author

Iizuka, T., Barre, A., Rougé, P., Charpin, D., Scala, E., Baudin, B., Aizawa, T., Sénéchal, H., and Poncet, P.

Subjects
General Medicine
Abstract

About 10 years ago, a protein family was shown for the first time to contain allergenic members, gibberellin-regulated protein (GRP). The first reported member was from peach, Pru p 7. One can hypothesize that it was not detected before because its physicochemical characteristics overlap with those of lipid transfer protein (LTP), a well-known allergen, or because the exposure to GRP increased due to an increase in the gibberellin phythormone level in plant food, either exogenous or endogenous. Like LTPs, GRPs are small cationic proteins with disulfide bridges, are resistant to heat and proteolytic cleavage, and are involved in the defense of the plant. Besides peach, GRP allergens have been described in Japanese apricot (Pru m 7), sweet cherry (Pru av 7), orange (Cit s 7), pomegranate (Pun g 7), bell pepper (Cap a 7), strawberry (Fra a GRP), and also in pollen with a restriction to Cupressaceae tree family (Cup s 7, Cry j 7, and Jun a 7). IgE cross-reactivities were described between GRPs, and the reported peach/cypress and citrus/cypress syndromes may therefore be explained because of these GRP cross-reactivities. GRPs are clinically relevant, and severe adverse reactions may sometimes occur in association with cofactors. More than 60% and up to 95% sequence identities are calculated between various allergenic GRPs, and three-dimensional models show a cleft in the molecule and predict at least three epitopic regions. The structure of the protein and its properties and the matrix effect in the original allergenic source should be unraveled to understand why, despite the ubiquity of the protein family in plants, only a few members are able to sensitize patients.

Published
2022

20. Allergie au pollen de Cupressacées : sensibilisation à Cry j 7 chez des enfants japonais allergiques au pollen de cèdre du Japon et aux fruits

Author

Iizuka, T., primary, Takei, M., additional, Saito, Y., additional, Rumi, F., additional, Zheng, J., additional, Lu, X., additional, Chafey, P., additional, Broussard, C., additional, Guilloux-Assalet, L., additional, Charpin, D., additional, Ebisawa, M., additional, Sénéchal, H., additional, Aizawa, T., additional, and Poncet, P., additional

Published
2021
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23. Protéines de lait de vache cachées

Author

De Ménibus, A.C., primary, Guiddir, T., additional, Billard, C., additional, Poncet, P., additional, Selva, M.A., additional, Sénéchal, H., additional, Chantran, Y., additional, and Nemni, A., additional

Published
2020
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36. Apport de l’allergologie moléculaire pour prédire l’évolution clinique d’enfants allergiques à l’arachide atteints de dermatite atopique à l’âge d’un an ou moins

Author

Poncet, P., primary, Longé, C., additional, Li, M.Y., additional, Amat, F., additional, Bouakkadia, H., additional, Rivera, O., additional, Sutra, J.P., additional, Selva, M.A., additional, Couderc, R., additional, Sénéchal, H., additional, and Just, J., additional

Published
2018
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39. Release of fine particles from Birch pollen grains following impaction

Author

Visez, N., Chassard, G., Azarkan, N., Naas, O., Sénéchal, H., Sutra, J.P., Poncet, Philippe, Choël, M., Physicochimie des Processus de Combustion et de l’Atmosphère - UMR 8522 (PC2A), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Dispositifs Micro-ondes et Matériaux pour les Energies Renouvelables, Université Ziane Achour de Djelfa, CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Département Infection et Epidémiologie - Department of Infection and Epidemiology, Institut Pasteur [Paris] (IP), Laboratoire Avancé de Spectroscopie pour les Intéractions la Réactivité et l'Environnement - UMR 8516 (LASIRE), Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], and Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Centrale Lille Institut (CLIL)

Subjects
[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry
Published
2015

40. Complementarity between microarray and immunoblot for the comparative evaluation of IgE repertoire of French and Italian cypress pollen allergic patients

Author

Youcef Shahali, Nicaise P, Brázdová A, Charpin D, Scala E, Mari A, Jp, Sutra, Chollet-Martin S, Sénéchal H, and Poncet P

Subjects
Adult, Male, Adolescent, Immunoblotting, Allergens, Cupressus, Immunoglobulin E, Middle Aged, Cohort Studies, Young Adult, Italy, Hypersensitivity, Prevalence, Humans, Pollen, Female, Immunization, France, Carrier Proteins, Child, Aged, Oligonucleotide Array Sequence Analysis, Plant Proteins
Abstract

Cypress pollen represents the primary cause of respiratory allergies in Mediterranean areas. Patients allergic to Cupressus sempervirens pollen (Cups) (CPA) can be discriminated on the basis of the immunoglobulin E (IgE) binding to a basic 14 kDa protein (BP14) or to high-molecular-weight (HMW) glycoproteins only. Specific IgE repertoires of two differentially exposed CPA cohorts, French and Italian, were investigated using an IgE microarray system (some known major allergens from several allergenic sources) and individual IgE immunoblotting (IB) of whole Cups pollen extract separated by SDS-PAGE (all allergens from one allergenic source: cypress pollen). The prevalence of sensitization to BP14 was higher in French (37 %) than in Italian patients (17 %) and major differences were observed in IgE reactivities to lipid transfer proteins (LTPs). Thirty percent of the Italian CPA (4 % in the French group) had specific IgE against the Parietaria pollen LTP, independently of IB subgroups. Regarding peach LTP sensitization, all Pru p 3+ Italian CPA (10 %) were in the HMW+ subgroup, while Pru p 3+ French CPA (20 %) were all included in the BP14+ subgroup. BP14 sensitization is likely a marker of Cups exposure and is, in French CPA, significantly correlated to Pru p 3 sensitization. The IgE immunoblot and microarray are complementary tools that highlight differences in the subtle sensitization profile between groups of patients in comparative studies.

Published
2014

41. Allergènes du pollen d’ortie (Urtica dioica)

Author

Tiotiu, A., primary, Morisset, M., additional, Brazdova, A., additional, Longé, C., additional, Dinard, K., additional, Leduc, V., additional, Broussard, C., additional, Chafey, P., additional, Couderc, R., additional, Sutra, J.P., additional, Sénéchal, H., additional, and Poncet, P., additional

Published
2016
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43. Bactéries multirésistantes (BMR) en milieu hospitalier : entérobactéries productrices de β-lactamases à spectre étendu (EBLSE) et Staphylococcus aureus résistants à la méticilline (Sarm ), Réseau BMR-Raisin, 2002-2010

Author

Arnaud, I., Jarlier, V., Carbonne-Berger, A., Maugat, S., Bajolet, O., Dumartin, C., Marty, Nicolas, Savey, Anne, Sénéchal, H., Coignard, B., Astagneau, P., Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), and Lyon 1, Depot 3

Subjects
[SDV] Life Sciences [q-bio], Surveillance, Staphylococcus aureus résistants à la méticilline (SARM), [SDV]Life Sciences [q-bio], Entérobactéries productrices de ²-lactamases à spectre étendu (EBLSE), Raisin, Bactéries multirésistantes (BMR)
Abstract

International audience; La maîtrise de la diffusion des bactéries multirésistantes (BMR) dans les établissements de santé (ES) est une priorité du Programme national de lutte contre les infections nosocomiales depuis le milieu des années 1990. Depuis 2002, le Raisin coordonne la surveillance nationale des Staphylococcus aureus résistants à la méticilline (SARM) et des entérobactéries productrices de ²-lactamases à spectre étendu (EBLSE), isolés de prélèvements à visée diagnostique dans les ES français. En 2010, 933 ES ont participé à la surveillance, soit une augmentation de 91% par rapport à 2002. En 2010, la densité d'incidence (DI) globale des SARM était de 0,40 pour 1 000 journées d'hospitalisation (IC95% : [0,39-0,41]) et celle des EBLSE de 0,39 [0,38-0,40]. De 2002 à 2010, la DI des SARM a diminué globalement de 43%, passant de 0,72 [0,70-0,74] à 0,41 [0,39-0,42] (p

Published
2012

46. Surveillance and outbreak reports

Author

Desenclos, J.-C., Astagneau, Pascal, Bernet, C., Bussy-Malgrange, V., Coignard, B., Dumartin, C., Fabry, J., Jarlier, V., Jarno, P., Lejeune, B., Thiolet, J.-M., May, L., Parneix, P., Rabaud, C., Salomon, V., Sénéchal, H., Savey, A., Talon, D., École des Hautes Études en Santé Publique [EHESP] (EHESP), Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]
Published
2009

50. O034: Regional trends in enterobacteriaceae extended-spectrum beta-lactamase-producing (ESBLE) and methicillin-resistant staphylococcus aureus (MRSA) between 2007 and 2011

Author

Arnaud, I, primary, Bajolet, O, additional, Bertrand, X, additional, Blanchard, H, additional, Caillat-Vallet, E, additional, Dumartin, C, additional, Eveillard, M, additional, Fosse, T, additional, Garreau, N, additional, Hoff, O, additional, Marty, N, additional, Maugat, S, additional, Reyreaud, E, additional, Savey, A, additional, Sénéchal, H, additional, Simon, L, additional, Sousa, E, additional, Trystram, D, additional, Coignard, B, additional, Jarlier, V, additional, and Astagneau, P, additional

Published
2013
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