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220 results on '"Säwe, J."'

5. Vaccination of children–a systematic review

Author

Örtqvist, Å, Blennow, M, Carlsson, R-M, Hanson, LÅ, Lindberg, A, Lindqvist, L, Magnusson, M, Nilsson, L, Norlund, A, Nyrén, O, Olcén, P, Olin, P, Silfverdal, S-A, Säwe, J, Söderström, A, and Trollfors, B

Published
2010
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23. Treatment of haemophilia A and B and von Willebrand's disease : summary and conclusions of a systematic review as part of a Swedish health-technology assessment

Author

Berntorp, E, Astermark, J, Baghaei, F, Bergqvist, David, Holmström, M, Ljungberg, B, Norlund, A, Palmblad, J, Petrini, P, Stigendal, L, Säwe, J, Berntorp, E, Astermark, J, Baghaei, F, Bergqvist, David, Holmström, M, Ljungberg, B, Norlund, A, Palmblad, J, Petrini, P, Stigendal, L, and Säwe, J

Abstract

In an ongoing health-technology assessment of haemophilia treatment in Sweden, performed by the governmental agency Dental and Pharmaceutical Benefits Agency (TLV; tandvårds-och läkemedelsförmånsverket), the Swedish Council on Health Technology Assessment (SBU; statens beredning för medicinsk utvärdering) was called upon to evaluate treatment of haemophilia A and B and von Willebrand's disease (VWD) with clotting factor concentrates. To evaluate the following questions: What are the short-term and long-term effects of different treatment strategies? What methods are available to treat haemophilia patients that have developed inhibitors against factor concentrates? Based on the questions addressed by the project, a systematic database search was conducted in PubMed, NHSEED, Cochrane Library, EMBASE and other relevant databases. The literature search covered all studies in the field published from 1985 up to the spring of 2010. In most instances, the scientific evidence is insufficient for the questions raised in the review. Concentrates of coagulation factors have good haemostatic effects on acute bleeding and surgical intervention in haemophilia A and B and VWD, but conclusions cannot be drawn about possible differences in the effects of different dosing strategies for acute bleeding and surgery. Prophylaxis initiated at a young age can prevent future joint damage in persons with haemophilia. The available treatment options for inhibitors have been insufficiently assessed. The economic consequences of various treatment regimens have been insufficiently analysed. Introduction of national and international registries is important.

Published
2012
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24. Vaccination of children : a children systematic review

Author

Örtqvist, Å, Blennow, M, Carlsson, R-M, Hansson, LÅ, Lindberg, A, Lindqvist, I, Magnusson, M, Nilsson, L, Norlund, A, Nyrén, O, Olcén, P, Olin, P, Silfverdal, Sven Arne, Säwe, J, Söderström, A, Trollfors, B, Örtqvist, Å, Blennow, M, Carlsson, R-M, Hansson, LÅ, Lindberg, A, Lindqvist, I, Magnusson, M, Nilsson, L, Norlund, A, Nyrén, O, Olcén, P, Olin, P, Silfverdal, Sven Arne, Säwe, J, Söderström, A, and Trollfors, B

Published
2010
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25. Benartärsjukdom - diagnostik och behandling. : En systematisk litteraturöversikt

Author

Bergqvist, David, Eckerlund, I, Holst, J, Jogestrand, T, Jörneskog, G, Klevsgård, R, Marké, L-Å, Matthiasson, I, Rolandsson, O, Syversson, A, Säwe, J, Troëng, T, Bergqvist, David, Eckerlund, I, Holst, J, Jogestrand, T, Jörneskog, G, Klevsgård, R, Marké, L-Å, Matthiasson, I, Rolandsson, O, Syversson, A, Säwe, J, and Troëng, T

Published
2007

26. Treatment of haemophilia A and B and von Willebrand’s disease: summary and conclusions of a systematic review as part of a Swedish health‐technology assessment

Author

BERNTORP, E., primary, ASTERMARK, J., additional, BAGHAEI, F., additional, BERGQVIST, D., additional, HOLMSTRÖM, M., additional, LJUNGBERG, B., additional, NORLUND, A., additional, PALMBLAD, J., additional, PETRINI, P., additional, STIGENDAL, L., additional, and SÄWE, J., additional

Published
2011
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27. ORIGINAL ARTICLE: Vaccination of children - a systematic review

Author

Örtqvist, Å, primary, Blennow, M, additional, Carlsson, R-M, additional, Hanson, LÅ, additional, Lindberg, A, additional, Lindqvist, L, additional, Magnusson, M, additional, Nilsson, L, additional, Norlund, A, additional, Nyrén, O, additional, Olcén, P, additional, Olin, P, additional, Silfverdal, S-A, additional, Säwe, J, additional, Söderström, A, additional, and Trollfors, B, additional

Published
2010
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50. Quinidine inhibition of debrisoquine S( )-4- and 7-hydroxylations in Chinese of different CYP2D6 genotypes

Author

Bertilsson, L, Meese, C O, Yue, Q Y, Dahl, M L, Ingelman-Sundberg, M, Johansson, I, Säwe, J, and Eichelbaum, M

Abstract

Pronounced differences in the CYP2D6 gene between Chinese and Caucasians have previously been described. There was a low frequency of detrimental mutations in the Chinese CYP2D6 gene causing the poor metabolizer (PM) phenotype. In contrast to Caucasians where the Xba 144 kb allele is almost always associated with the PM phenotype, Chinese with the 4444 kb RFLP pattern are extensive metabolizers (EM). In order to evaluate whether the debrisoquine hydroxylation seen in subjects with this haplotype is catalysed by a functionally similar enzyme to CYP2D6 or is catalysed by another type of P450 isozyme, product selectivity of the 4-hydroxylation was studied in 27 Chinese. The inhibition of CYP2D6 by quinidine was also investigated.

Published
1993

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