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1. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

2. Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets

3. The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies

4. Autoantibodies Neutralizing Type III Interferons Are Uncommon in Patients with Severe Coronavirus Disease 2019 Pneumonia.

5. Autoantibodies against type I IFNs in patients with critical influenza pneumonia

6. The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies

7. Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children

8. Autoantibodies against type I IFNs in patients with critical influenza pneumonia.

9. The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies.

10. Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

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