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21 results on '"Sánchez-Ragnarsson, Cecilia"'

1. Consumption of health resources in older people with differentiated thyroid carcinoma: a multicenter analysis

Author

Díez, Juan J., Anda, Emma, Alcazar, Victoria, Isidro, María L., Familiar, Cristina, Paja, Miguel, Martín Rojas-Marcos, Patricia, Pérez-Corral, Begoña, Navarro, Elena, Romero-Lluch, Ana R., Oleaga, Amelia, Pamplona, María J., Fernández-García, José C., Megía, Ana, Manjón-Miguélez, Laura, Sánchez-Ragnarsson, Cecilia, Iglesias, Pedro, and Sastre, Julia

Published
2023
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2. Differentiated thyroid carcinoma in the elderly: influence of age on disease-free and overall survival

Author

Díez, Juan J., Anda, Emma, Alcazar, Victoria, Isidro, María L., Familiar, Cristina, Paja, Miguel, Rojas Marcos, Patricia, Pérez-Corral, Begoña, Navarro, Elena, Romero-Lluch, Ana R., Oleaga, Amelia, Pamplona, María J., Fernández-García, José C., Megía, Ana, Manjón, Laura, Sánchez-Ragnarsson, Cecilia, Iglesias, Pedro, and Sastre, Julia

Published
2022
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4. Prevalence of chronic postsurgical hypoparathyroidism not adequately controlled: an analysis of a nationwide cohort of 337 patients.

Author

Díez, Juan J., Anda, Emma, Pérez-Corral, Begoña, Paja, Miguel, Alcazar, Victoria, Sánchez-Ragnarsson, Cecilia, Orois, Aida, Romero-Lluch, Ana R., Sambo, Marcel, Oleaga, Amelia, Caballero, Águeda, Alhambra, María R., Urquijo, Virginia, Delgado-Lucio, Ana M., Fernández-García, José C., Doulatram-Gamgaram, Viyey K., Dueñas-Disotuar, Suset, Martín, Tomás, Peinado, Mercedes, and Sastre, Julia

Subjects
CHRONIC kidney failure, GLOMERULAR filtration rate, EYE diseases, HYPOPARATHYROIDISM, KIDNEY stones
Abstract

Purpose: The identification of patients with chronic hypoparathyroidism who are adequately (AC) or not adequately controlled (NAC) has clinical interest, since poor disease control is related to complications and mortality. We aimed to assess the prevalence of NAC patients in a cohort of subjects with postsurgical hypoparathyroidism. Methods: We performed a multicenter, retrospective, cohort study including patients from 16 Spanish hospitals with chronic hypoparathyroidism lasting ≥3 years. We analyzed disease control including biochemical profile and clinical wellness. For biochemical assessment we considered three criteria: criterion 1, normal serum calcium, phosphorus and calcium x phosphorus product; criterion 2, the above plus estimated glomerular filtration rate ≥60 ml/min/1.73 m2 ; and criterion 3, the above plus normal 24-hour urinary calcium excretion. A patient was considered AC if he or she met the biochemical criteria and was clinically well. Results: We included 337 patients with postsurgical hypoparathyroidism (84.3% women, median age 45[36-56] years, median time of follow-up 8.9[6.0-13.0] years). The proportions of NAC patients with criteria 1, 2 and 3 were, respectively, 45.9%, 49.2% and 63.1%. Patients who had dyslipidemia at the time of diagnosis presented a significantly higher risk of NAC disease (criterion 3; OR 7.05[1.44- 34.45]; P=0.016). NAC patients (criterion 2) had a higher proportion of subjects with incident chronic kidney disease and eye disorders, and NAC patients (criterion 3) had a higher proportion of incident chronic kidney disease, nephrolithiasis and dyslipidemia than AC patients. Conclusion: The present study shows a strikingly high prevalence of NAC patients in the clinical practice of Spanish endocrinologists. Results suggest that NAC disease might be associated with some prevalent and incident comorbidities. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Recovery of parathyroid function in patients with thyroid cancer treated by total thyroidectomy: An analysis of 685 patients with hypoparathyroidism at discharge of surgery

Author

Díez, Juan J., Anda, Emma, Sastre, Julia, Pérez-Corral, Begoña, Álvarez-Escolá, Cristina, Manjón, Laura, Paja, Miguel, Sambo, Marcel, Santiago-Fernández, Piedad, Blanco-Carrera, Concepción, Galofré, Juan C., Navarro, Elena, Zafón, Carles, Sanz, Eva, Oleaga, Amelia, Bandrés, Orosia, Donnay, Sergio, Megía, Ana, Picallo, María, Sánchez-Ragnarsson, Cecilia, Baena-Nieto, Gloria, Fernández-García, José Carlos, Lecumberri, Beatriz, Vega, Manel Sahún de la, Romero-Lluch, Ana R., and Iglesias, Pedro

Published
2021
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6. Incident comorbidities in patients with chronic hypoparathyroidism after thyroidectomy: a multicenter nationwide study

Author

Díez, Juan J., primary, Anda, Emma, additional, Pérez-Corral, Begoña, additional, Paja, Miguel, additional, Alcázar, Victoria, additional, Sánchez-Ragnarsson, Cecilia, additional, Orois, Aida, additional, Romero-Lluch, Ana R., additional, Sambo, Marcel, additional, Oleaga, Amelia, additional, Caballero, Águeda, additional, Alhambra, María R., additional, Urquijo, Virginia, additional, Delgado-Lucio, Ana M., additional, Fernández-García, José C., additional, Kishore-Doulatram, Viyey, additional, Dueñas-Disotuar, Suset, additional, Martín, Tomás, additional, Peinado, Mercedes, additional, and Sastre, Julia, additional

Published
2024
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9. Prevalence and risk factors for hypoparathyroidism following total thyroidectomy in Spain: a multicentric and nation-wide retrospective analysis

Author

Díez, Juan J., Anda, Emma, Sastre, Julia, Pérez Corral, Begoña, Álvarez-Escolá, Cristina, Manjón, Laura, Paja, Miguel, Sambo, Marcel, Santiago Fernández, Piedad, Blanco Carrera, Concepción, Galofré, Juan C, Navarro, Elena, Zafón, Carles, Sanz, Eva, Oleaga, Amelia, Bandrés, Orosia, Donnay, Sergio, Megía, Ana, Picallo, María, Sánchez Ragnarsson, Cecilia, Baena-Nieto, Gloria, García, José Carlos Fernández, Lecumberri, Beatriz, de la Vega, Manel Sahún, Romero-Lluch, Ana R., and Iglesias, Pedro

Published
2019
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10. Consumption of health resources in older people with differentiated thyroid carcinoma: a multicenter analysis

Author

Díez, Juan J., primary, Anda, Emma, additional, Alcazar, Victoria, additional, Isidro, María L., additional, Familiar, Cristina, additional, Paja, Miguel, additional, Rojas-Marcos, Patricia Martín, additional, Pérez-Corral, Begoña, additional, Navarro, Elena, additional, Romero-Lluch, Ana R., additional, Oleaga, Amelia, additional, Pamplona, María J., additional, Fernández-García, José C., additional, Megía, Ana, additional, Manjón-Miguélez, Laura, additional, Sánchez-Ragnarsson, Cecilia, additional, Iglesias, Pedro, additional, and Sastre, Julia, additional

Published
2023
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11. Correction to: Prevalence and risk factors for hypoparathyroidism following total thyroidectomy in Spain: a multicentric and nation-wide retrospective analysis

Author

Díez, Juan J., Anda, Emma, Sastre, Julia, Pérez Corral, Begoña, Álvarez-Escolá, Cristina, Manjón, Laura, Paja, Miguel, Sambo, Marcel, Santiago Fernández, Piedad, Blanco Carrera, Concepción, Galofré, Juan Carlos, Navarro, Elena, Zafón, Carles, Sanz, Eva, Oleaga, Amelia, Bandrés, Orosia, Donnay, Sergio, Megía, Ana, Picallo, María, Sánchez Ragnarsson, Cecilia, Baena-Nieto, Gloria, Fernández García, José Carlos, Lecumberri, Beatriz, Sahún de la Vega, Manel, Romero-Lluch, Ana R., and Iglesias, Pedro

Published
2019
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14. Permanent postoperative hypoparathyroidism: an analysis of prevalence and predictive factors for adequacy of control in a cohort of 260 patients

Author

Díez, Juan J., primary, Anda, Emma, additional, Sastre, Julia, additional, Pérez Corral, Begoña, additional, Álvarez-Escolá, Cristina, additional, Manjón, Laura, additional, Paja, Miguel, additional, Sambo, Marcel, additional, Santiago Fernández, Piedad, additional, Blanco Carrera, Concepción, additional, Galofré, Juan C., additional, Navarro, Elena, additional, Zafón, Carles, additional, Sanz, Eva, additional, Oleaga, Amelia, additional, Bandrés, Orosia, additional, Donnay, Sergio, additional, Megía, Ana, additional, Picallo, María, additional, Sánchez Ragnarsson, Cecilia, additional, Baena-Nieto, Gloria, additional, Fernández-García, José Carlos, additional, Lecumberri, Beatriz, additional, Sahún de la Vega, Manel, additional, Romero-Lluch, Ana R., additional, and Iglesias, Pedro, additional

Published
2020
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15. Prevalence and risk factors for hypoparathyroidism following total thyroidectomy in Spain: a multicentric and nation-wide retrospective analysis

Author

Díez, Juan José, Anda, Emma, Sastre, Julia, Pérez Corral, Begoña, Álvarez-Escolá, Cristina, Manjón, Laura, Paja, Miguel, Sambo, Marcel, Santiago Fernández, Piedad, Blanco Carrera, Concepción, Galofré, J. C., Navarro-Villarán, Elena, Zafón, Carles, Sanz, Eva, Oleaga, Amelia, Bandrés, Orosia, Donnay, Sergio, Megía, Ana, Picallo, María, Sánchez Ragnarsson, Cecilia, Baena-Nieto, Gloria, Fernández-García, José C., Lecumberri, Beatriz, Sahún de la Vega, Manel, Romero-Lluch, Ana R., Iglesias, Pedro, Díez, Juan José, Anda, Emma, Sastre, Julia, Pérez Corral, Begoña, Álvarez-Escolá, Cristina, Manjón, Laura, Paja, Miguel, Sambo, Marcel, Santiago Fernández, Piedad, Blanco Carrera, Concepción, Galofré, J. C., Navarro-Villarán, Elena, Zafón, Carles, Sanz, Eva, Oleaga, Amelia, Bandrés, Orosia, Donnay, Sergio, Megía, Ana, Picallo, María, Sánchez Ragnarsson, Cecilia, Baena-Nieto, Gloria, Fernández-García, José C., Lecumberri, Beatriz, Sahún de la Vega, Manel, Romero-Lluch, Ana R., and Iglesias, Pedro

Abstract

[Purpose]: The prevalence of postoperative hypoparathyroidism has been studied in registries and in surgical series with highly variable and imprecise results. However, the frequency of this hormonal deficiency in the clinical practice of endocrinologists is not known with accuracy. We aimed to assess the prevalence and risk factors of hypoparathyroidism in patients undergoing total thyroidectomy in Spain. [Methods]: We designed a retrospective, multicentre and nation-wide protocol including all patients with total thyroidectomy who were seen in the endocrinology clinic of the participant centers from January to March 2018. Prevalence of hypoparathyroidism was evaluated at discharge of surgery, 3–6 months after surgery, 12 months after surgery and at last visit. Twenty hospitals participated in the study. [Results]: Of 1792 patients undergoing total thyroidectomy, 866 (48.3%) developed postoperative hypoparathyroidism at discharge of surgery. Most of them recover parathyroid function over time. Prevalence of hypoparathyroidism at 3–6 months, 12 months and at last visit was 22.9%, 16.7% and 14.5%, respectively. The risk of developing definitive hypoparathyroidism was related to the presence of parathyroid tissue at histology, lymph node dissection, and two-stage thyroidectomy. Patients with thyroid cancer, with higher postoperative calcium levels and treated by expert surgical teams exhibited lower risk of developing permanent hypoparathyroidism. [Conclusions]: Although most patients with postsurgical hypoparathyroidism recover parathyroid function, the prevalence of permanent disease in clinical practice is non negligible (14.5%). Postoperative calcium, extent and timing of surgery, the presence of cancer, expert surgical team, and parathyroid tissue at histology are predictors of permanent hypoparathyroidism.

Published
2019

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