299 results on '"Rywik S"'
Search Results
2. Psychosocial Work Characteristics and Self Rated Health in Four Post-Communist Countries
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Pikhart, H., Bobak, M., Siegrist, J., Pajak, A., Rywik, S., Kyshegyi, J., Gostautas, A., Skodova, Z., and Marmot, M.
- Published
- 2001
3. Working group on epidemiology & prevention of the european society of cardiology: Proceedings of meeting held at Shannon May 14th–17th, 1998
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Sullivan, P. A., Murphy, D., Sullivan, P. A., Keogh, S., Sullivan, P. A., Nash, P., Kaarisalo, M. M., Marttila, J., Immonen-Raiha, P., Salomaa, V., Torppa, J., Tuomilehto, J., Siani, A., Racone, R., Ragone, E., Stinga, F., Strazzullol, P., Cappuccio, F. P., Trevisan, M., Farinaro, E., Mellone, C., Fox, K. F., Cowie, M. R., Wood, D. A., Coats, A. J., Poole Wilson, P. A., Sutton, G. C., Yarnell, J., Sweetnam, P., Thomas, H., Piwonski, J., Piotrowski, W., Pytlak, A., Wannamethee, S. G., Shaper, A. G., Walker, M., Sharpe, P. C., Young, I. S., Hasselwander, O., McMaster, D., Mercer, C., McGrath, L. T., Evans, A. E., Thomas, F., Guize, L., Ducimetiere, P., Benetos, A., Rosolova, H., Simon, J., Mayer, O., Sefrna, F., Mayer, O., Šimon, J., Rosolova, H., Racek, J., Trefil, L., Marin-Tarlea, M., Carp, C., Apetrei, E., Ginghina, C., Serban, I., Florica, N., Ceck, C., Patrascoiu, M., Ginghina, C., Carp, C., Apetrei, E., Tarlea, M., Cioranu, R., Florica, N., Ceck, C., Vaduva, M., Mihaescu, D., Lapadat, M., Ashton, W. D., Wood, D., Nanchahahal, K., Kelleher, C. C., Brennan, P. J., Howarth, D., Meade, T. W., Kelleher, C. C., Fallon, U. B., McCarthy, U., O’Donnell, M. M. K., Dineen, B., Jousilahti, P., Vartiainen, E., Tuomilehto, J., Puska, P., Kastarinen, M., Nissinen, A., Salomaa, V., Vartiainen, E., Jousilahti, P., Tuomilehto, J., Puska, P., Rosengren, A., Wedel, H., Wilhelmsen, L., Liese, A. D., Hense, H. W., Keil, U., Keil, U., Liese, A. D., Hense, H. W., Filipiak, B., Döring, A., Stieber, J., Lowel, H., De Laet, C., Brasseur, D., Kahn, A., Wautrecht, J. C., Decuyper, J., Boeynaems, J. M., Jousilahti, P., Vartiainen, E., Tuomilehto, J., Sundvall, J., Puska, P., Marques-Vidal, P., Ferrières, J., Haas, B., Evans, A., Amouyel, P., Luc, G., Ducimetiere, P., Marques-Vidal, P., Ferrieres, J., Arveiler, D., Montaye, M., Evans, A., Ducimetiere, P., Fuentes, R., Notkola, I. -L., Shemeikka, S., Tuomilehto, J., Nissinen, A., Mak, R., De BacquerBacquer, D., De Backer, G., Stam, M., Koyuncu, R., de Smet, P., Kornitzer, M., Braeckman, L., De Backer, G., De Bacquer, D., Claeys, L., Delanghe, J., De Bacquer, D., Kornitzer, M., De Backer, G., Cífkova, R., Pit’ha, J., Červenka, L., Šejda, T., Lanska, V., Škodová, Z., Stavek, P., Poledne, R., Cífková, R., Duskova, A., Hauserová, G., Hejl, Z., Lánská, V., Škodova, Z., Pistulková, H., Poledne, R., Hubáček, J., Pit’ha, J., Stávek, P., Lánská, V., Cífková, R., Faleiro, L. L., Rodrigues, D., Fonseca, A., Martins, M. C., Norris, R. M., Nyyssönen, K., Seppänen, K., Salonen, R., Kantola, M., Salonen, J. T., Parviainen, M. T., De Henauw, S., Myny, K., Doyen, Z., Van Oyen, H., Tafforeau, J., Kornitzer, M., De Backer, G., Benetos, A., Thomas, F., Guize, L., Immonen-Räihä, P., Kaarisalo, M., Marttila, R. J., Torppa, J., Tuomilehto, J., Houterman, S., Hofman, B., Witteman, J. C. M., Verschuren, W. M. M., van de Vijver, L. P. L., Kardinaal, A. F. M., Grobbee, D. E., van Poppel, G., Princen, H. M. G., Kornitzer, M., Doven, M., Koyuncu, R., De Bacquer, D., Myny, K., De Backer, G., Tafforeau, J., Van Oven, H., Doyen, M., Koyuncu, R., Kornitzer, M., De Bacquer, D., Myny, K., De Backer, G., Tafforeau, J., Van Oyen, H., de Bree, A., Verschuren, W. M. M., Blom, H. J., Mulder, I., Smit, H. A., Menotti, A., Kromhout, D., Van den Hoogen, P. C. W., Hofman, A., Witteman, J. C. M., Feskens, E. J. M., Štika, L., Bruthans, J., Wierzbicka, M., Bolinska, H., Voutilainen, S., Nyyssönen, K., Salonen, R., Lakka, T. A., Salonen, J. T., Lakka, H -M., Lakka, T. A., Salonen, J. T., Tuomainen, T-P., Nyyssonen, K., Salonen, J. T., Punnonen, K., Yarnell, J., Patterson, C., Thomas, H., Sweetnam, P., Smith, W. C. S., Campbell, S. E., Cardy, A., Phillips, D. O., Helms, P. J., Squair, J., Smith, W. C. S., Cardy, A., Phillips, D. O., Helms, P. J., Squair, J., Smith, W. C. S., Cardy, A., Phillips, D. O., Helms, P. J., Squair, J., Pytlak, A., Piotrowski, W., Rywik, S., Waskiewicz, A., Sygnowska, E., Szczesniewska, D., Sygnowska, E., Waskiewicz, A., Wagrowska, H., Polakowska, M., Rywik, S., Broda, G., Jasinski, B., Piotrowski, W., Elandt-Johnson, R. C., Wagrowska, H., Kupsé, W., Szczesniewska, D., Platonov, D. Y., Haapanen, N., Miilunpalo, S., Vuori, I., Pasanen, M., Oja, P., Urponen, H., Kopp, M. S., Skrabski, A., Szedmák, S., Boaz, M., Biro, A., Katzir, Z., Matas, T., Smetana, S., Green, M., Whincup, P. H., Morris, R., Walker, M., Lennon, L., Thomson, A., Ebrahim, S. J. B., Refsum, H., Ueland, P. M., Perry, I. J., Boer, J. M. A., Kuivenhoven, J. A., Feskens, E. J. M., Schouten, E. G., Havekes, L. M., Seidell, J. C., Kastelein, J. J. P., Kromhout, D., Oomen, C. M., Feskens, E. J. M., Rasanen, L., Nissinen, A., Fidanza, F., Menotti, A., Kok, F. J., Kromhout, D., Sileikiene, L., Klambienne, J., Milasauskiene, Z., Cappuccio, F. P., Siani, A., Barba, G., Russo, L., Ragone, E., Strazzullo, P., Farinaro, E., Trevisan, M., Schnohr, P., Parner, J., Lange, P., Meleady, R., Graham, I. M., Ueland, P. M., Refsum, H., Blom, H., Whitehead, A. S., Daly, L. E., Stefanovic, B., Boskovic, D., Mitrovic, P., Perunicic, J., Vukcevic, V., Radovanovic, N., Terzic, B., Mrdovic, I., Orilc, D., Matic, G., Vasiljevic, Z., Mitrovic, P., Boskovic, D., Stefanovic, B., Perunicic, J., Vukcevic, V., Mrdovic, I., Radovanovic, N., Orlic, D., Matic, G., Milentijevic, B., Rajic, D., Mitrovic, N., Boskovic, S., Vasiljevic, Z., Marin-Tarlea, M., Carp, C., Apetrei, E., Serban, I., Ceck, C., Patrascsoiu, M., Florica, N., Mihaescu, D., Murphy, C., Meleady, R., Ingram, S., Love, J., Graham, I., Graham, I. M., Meleady, R., van Berkel, T. F. M., Deckers, J. W., and De Bacquer, D.
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- 1998
- Full Text
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4. Blood pressure levels in the 41 populations of the WHO MONICA Project
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Wolf, HK, Tuomilehto, J, Kuulasmaa, K, Domarkiene, S, Cepaitis, Z, Molarius, A, Sans, S, Dobson, A, Keil, U, and Rywik, S
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- 1997
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5. The contribution of educational class in improving accuracy of cardiovascular risk prediction across European regions: The MORGAM Project Cohort Component
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Ferrario, MARCO MARIO ANGELO, Veronesi, Giovanni, Chambless, L., Tunstall Pedoe, H., Kuulasmaa, K., Salomaa, V., Borglykke, A., Hart, N., Söderberg, S., Cesana, G., Jørgensen, T., Agger, C., Juolevi, A., Vartiainen, E., Jousilahti, P., Cepaitis, Z., Haukijärvi, A., Joseph, B., Kulathinal, S., Niemelä, M., Saarela, O., Ducimetière, P., Bingham, A., Arveiler, D., Haas, B., Wagner, A., Ferrières, J., Ruidavets, J., Bongard, V., Amouyel, P., Montaye, M., Dallongeville, J., Döring, A., Wichmann, E., Fornari, C., Sega, R., Mancia, G., Facchetti, R., Vanuzzo, D., Pilotto, L., Picco, F., Mattiussi, F., Gigante, S., Tamosiunas, A., Domarkiene, S., Rastenyte, D., Bernotiene, G., Radisauskas, R., Baceviciene, M., Luksiene, D., Malinauskiene, V., Bernotaite, L., Pajak, A., Kawalec, E., Broda, G., Kurjata, P., Rywik, S., Polakowska, M., Pytlak, A., Nikitin, Y., Malyutina, S., Gafarov, V., Feigin, V., Siminova, G., Voevoda, M., Vinogradova, T., Nasonova, N., Veriovkin, E., Eliasson, M., Stegmayr, B., Eriksson, M., Asplund, K., Kee, F., Evans, A., Yarnell, J., Gardner, E., Woodward, M., Cashman, S., Blankenberg, S., Palotie, A., Perola, M., Peters, A., Tregouet, D., Cambien, F., Tiret, L., Peltonen, L., Shields, D., and Wiklund, P.
- Subjects
Adult ,Male ,Pathology ,medicine.medical_specialty ,Socioeconomic position ,Disease ,Risk Assessment ,Patient Education as Topic ,Predictive Value of Tests ,Risk Factors ,Environmental health ,Component (UML) ,Epidemiology ,medicine ,Humans ,Prospective Studies ,business.industry ,Middle Aged ,Class (biology) ,Europe ,Survival Rate ,Socioeconomic Factors ,Cardiovascular Diseases ,Cohort ,Educational Status ,Female ,Morbidity ,Cardiology and Cardiovascular Medicine ,business ,Follow-Up Studies - Abstract
To assess whether educational class, an index of socioeconomic position, improves the accuracy of the SCORE cardiovascular disease (CVD) risk prediction equation.In a pooled analysis of 68 455 40-64-year-old men and women, free from coronary heart disease at baseline, from 47 prospective population-based cohorts from Nordic countries (Finland, Denmark, Sweden), the UK (Northern Ireland, Scotland), Central Europe (France, Germany, Italy) and Eastern Europe (Lithuania, Poland) and Russia, we assessed improvements in discrimination and in risk classification (net reclassification improvement (NRI)) when education was added to models including the SCORE risk equation.The lowest educational class was associated with higher CVD mortality in men (pooled age-adjusted HR=1.64, 95% CI 1.42 to 1.90) and women (HR=1.31, 1.02 to 1.68). In men, the HRs ranged from 1.3 (Central Europe) to 2.1 (Eastern Europe and Russia). After adjustment for the SCORE risk, the association remained statistically significant overall, in the UK and Eastern Europe and Russia. Education significantly improved discrimination in all European regions and classification in Nordic countries (clinical NRI=5.3%) and in Eastern Europe and Russia (NRI=24.7%). In women, after SCORE risk adjustment, the association was not statistically significant, but the reduced number of deaths plays a major role, and the addition of education led to improvements in discrimination and classification in the Nordic countries only.We recommend the inclusion of education in SCORE CVD risk equation in men, particularly in Nordic and East European countries, to improve social equity in primary prevention. Weaker evidence for women warrants the need for further investigations.
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- 2014
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6. Prevalence of diabetes mellitus, coronary heart disease and hypertension in the families of insulin dependent and insulin independent diabetics
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Królewski, A. S., Czyżyk, A., Kopczyński, J., and Rywik, S.
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- 1981
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7. THE RELATIONSHIP OF HYPERLIPOPROTEINEMIA TO OTHER CORONARY RISK FACTORS IN A MALE POPULATION AGED 20–50 YEARS
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Chotkowska, E., primary, Charzewska, J., additional, Szostak, W.B., additional, and Rywik, S., additional
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- 1981
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8. The relation of body mass index and abdominal adiposity with dyslipidemia in 27 general populations of the WHO MONICA Project
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Hobbs, M, Jamrozik, K, Thompson, P, Armstrong, B, de Backer, G, De Craene, I, Van Onsem, P, Van Parys, L, De Henauw, S, De Bacquer, D, Kornitzer, M, Berghmans, L, Bara, L, de Smet, P, Jeanjean, M, Brohet, C, Kulbertus, H, Degre, S, Lavenne, F, Jansens, D, Lefebvre, F, Beck, D, Wunsch, G, Bertrand, F, van Houte, M, Rime, B, Rorive, G, Hannot, R, Adrienne, A, Luyckx, A, Wolf, H, Gregor, R, Bata, I, Brownell, B, Webber, K, Skodova ́, Z, Pisa, Z, Berka, L, Cicha, Z, Cerovska ́, J, Emrova ́, R, Hoke, M, Hronkova, M, Pikhartova ́, J, Grafnetter, D, Poledne, R, Vojtisek, P, Vorlicek, J, Wiesner, E, Schroll, M, Kirchhoff, M, Sjøl, A, Quitsau Lund, S, Tuomilehto, J, Puska, P, Vartiainen, E, Korhonen, H, Jousilahti, M, Ducimetie`re, P, Richard, J, Bingham, A, Lang, T, Amouyel, P, Cottel, D, Nuttens, M, Marecaux, N, Dallongeville, J, Salomez, J, Montaye, M, Steclebout, C, Arveiler, D, Schaffer, P, Haas, V, Wagner, A, Lamamy, N, Savouret, M, Houset, M, Pierau, F, Goetz, V, Ferrie`res, J, Ruidavets, J, Cambou, J, Rodier, P, Saulet, C, Greiser, E, Herman, B, Stu ̈demann, G, Nu ̈ssel, E, Osto ̈r Lamm, E, Scheidt, R, Morgenstern, W, Stadler, M, Ganova, M, Keil, U, Tietze, M, Banos, R, Do ̈ring, A, Filipiak, B, Barth, W, Heinemann, L, Muche, J, Schmalfuss, S, Assmann, A, Bo ̈thig, S, Voigt, G, Brasche, S, Quietzsch, D, Classen, E, Sigfu ́sson, N, Gudmundsdo ́ttir, I, Stefa ́nsdo ́ttir, I, Thorsteinsson, T, Sigvaldason, H, Menotti, A, Giampaoli, S, Verdecchia, A, Righetti, G, De Pasquale, B, Di Raimo, P, Forte, E, Majetta, A, Vanuzzo, D, Feruglio, G, Pilotto, L, Cignacco, G, Marini, R, Zilio, G, Cesana, G, Ferrario, M, Sega, R, Mocarelli, P, Brambilla, P, Bluzhas, J, Domarkiene, S, Tamosiunas, A, Reklaitiene, R, Beaglehole, R, Jackson, R, Bonita, R, Stewart, A, Mahon, V, Bingley, W, Pajak, A, Sznajd, J, Kawalec, E, Pazucha, T, Malczewska, M, Mo ́rawska, I, Rywik, S, Broda, V, Polakowska, M, Kurjata, P, Varlamova, A, Britov, A, Konstantinov, V, Timofeeva, V, Alexandri, V, Konstantinova, O, Nikitin, Y, Malyutina, S, Gafarov, V, Feigin, V, Sans, S, Balaguer Vintro ́, V, Balana`, V, Gonzalez, V, Gomez, V, Borras, V, Rode ́s, A, Wilhelmsen, L, Harmsen, P, Rosengren, A, Lappas, G, Asplund, K, Huhtasaari, F, Stegmayr, B, Lundberg, V, Gutzwiller, F, Paccaud, F, Rickenbach, M, Wietlisbach, V, Barazzoni, F, Mainieri, F, Tullen, B, Evans, V, Mccrum, E, Falconer, T, Cashman, S, Patterson, C, Kerr, M, O’Reilly, D, Scott, A, Mcconville, M, Mcmillan, I, Mcmaster, D, Tunstall Pedoe, H, Smith, W, Tavendale, R, Crombie, V, Barrett, K, Brown, C, Shewry, M, Hannh, M, Morrisson, C, Planojevic, M, Jakovljevic, D, Svircevic, A, Mirilov, V, Strasser, V, Mendis, S, Martin8, I, Gyarfas8, V, Pı ́_sa8, V, Dodu8, S, Bo ̈thig8, S, Watson, M, Hill, M, Price, A, Kuulasmaa, K, Ruokokoski, E, Rajakangas, A, Ma ̈kinen, M, Virman Ojanen, T, Palonen, L, Akkila, J, Cepaitis, Z, Molarius, A, Moltchanov, V, Tolonen, H, Dobson, A, Fortmann, S, Shatchkute, A, Zaitsev, V, Epstein, F, Feinleib, M, Karvonen, M, Prineas, R, Williams, O, Hobbs, MST, Jamrozik, K., Thompson, PL, Armstrong, BK, Van Parys, L., Berghmans, L., Kulbertus, HE, Lefebvre, F., Wunsch, G., Bertrand, F., van Houte, M., Rime, B., Hannot, R., Wolf, HK, Gregor, RD, Bata, IR, Brownell, B., Pisa, Z., Berka, L., Cicha, Z., Hronkova, M., Pikhartova ́, J., Grafnetter, D., Poledne, R., Vojtisek, P., Vorlicek, J., Sjøl, A., Puska, P., Vartiainen, E., Korhonen, H., Richard, JL, Bingham, A., Cottel, D., Nuttens, MC, Marecaux, N., Dallongeville, J., Salomez, J. L., Montaye, M., Lamamy, N., Houset, M., Pierau, F., Ruidavets, JB, Cambou, JP, Rodier, P., Greiser, E., Herman, B., Nu ̈ssel, E., Osto ̈r Lamm, E., Scheidt, R., Morgenstern, W., Tietze, M., Banos, R., Do ̈ring, A., Muche, J., Schmalfuss, S., Assmann, A., Bo ̈thig, S., Voigt, G., Brasche, S., Quietzsch, D., Gudmundsdo ́ttir, II, Thorsteinsson, T., Sigvaldason H, Giampaoli, S., Righetti, G., De Pasquale, B., Forte, E., Feruglio, GA, Pilotto, L., Cignacco, G., Marini, R., Cesana, GC, Sega, R., BRAMBILLA, PAOLO, Domarkiene, S., Tamosiunas, A., Stewart, A., Kawalec, E., Pazucha, T., Malczewska, M., Rywik, SL, Broda,V, Polakowska, M., Britov, A., Nikitin, Y.u. P, Malyutina, S., Sans, S., Harmsen, P., Rosengren, A., Asplund, K., Huhtasaari, F., Stegmayr, B., Lundberg V, Paccaud, F., Rickenbach, M., Wietlisbach, V., Mainieri, F., McCrum, EE, Cashman, S., Patterson, C., Kerr, M., O’Reilly, D., Scott, A., McConville, M., McMillan, I., McMaster, D, Tunstall Pedoe, H., Smith, WCS, Tavendale, R., Barrett, K., Brown, C., Shewry, M., Hannh, M. K, Jakovljevic, D., Svircevic, A., Mirilov, V., Strasser, V., Mendis, S., Dodu8, S. R. A., Bo ̈thig8, S., Watson, M. J., Hill, M., Kuulasmaa, K., Tuomilehto, J., Rajakangas, A. M., Ma ̈kinen, M., Palonen, L., Cepaitis, Z., Molarius, A., Moltchanov, V., Dobson, A., Fortmann, SP, Epstein, FH, Karvonen, MJ, Prineas, RJ, Williams, OD, Hobbs, M, Jamrozik, K, Thompson, P, Armstrong, B, de Backer, G, De Craene, I, Van Onsem, P, Van Parys, L, De Henauw, S, De Bacquer, D, Kornitzer, M, Berghmans, L, Bara, L, de Smet, P, Jeanjean, M, Brohet, C, Kulbertus, H, Degre, S, Lavenne, F, Jansens, D, Lefebvre, F, Beck, D, Wunsch, G, Bertrand, F, van Houte, M, Rime, B, Rorive, G, Hannot, R, Adrienne, A, Luyckx, A, Wolf, H, Gregor, R, Bata, I, Brownell, B, Webber, K, Skodova ́, Z, Pisa, Z, Berka, L, Cicha, Z, Cerovska ́, J, Emrova ́, R, Hoke, M, Hronkova, M, Pikhartova ́, J, Grafnetter, D, Poledne, R, Vojtisek, P, Vorlicek, J, Wiesner, E, Schroll, M, Kirchhoff, M, Sjøl, A, Quitsau Lund, S, Tuomilehto, J, Puska, P, Vartiainen, E, Korhonen, H, Jousilahti, M, Ducimetie`re, P, Richard, J, Bingham, A, Lang, T, Amouyel, P, Cottel, D, Nuttens, M, Marecaux, N, Dallongeville, J, Salomez, J, Montaye, M, Steclebout, C, Arveiler, D, Schaffer, P, Haas, V, Wagner, A, Lamamy, N, Savouret, M, Houset, M, Pierau, F, Goetz, V, Ferrie`res, J, Ruidavets, J, Cambou, J, Rodier, P, Saulet, C, Greiser, E, Herman, B, Stu ̈demann, G, Nu ̈ssel, E, Osto ̈r Lamm, E, Scheidt, R, Morgenstern, W, Stadler, M, Ganova, M, Keil, U, Tietze, M, Banos, R, Do ̈ring, A, Filipiak, B, Barth, W, Heinemann, L, Muche, J, Schmalfuss, S, Assmann, A, Bo ̈thig, S, Voigt, G, Brasche, S, Quietzsch, D, Classen, E, Sigfu ́sson, N, Gudmundsdo ́ttir, I, Stefa ́nsdo ́ttir, I, Thorsteinsson, T, Sigvaldason, H, Menotti, A, Giampaoli, S, Verdecchia, A, Righetti, G, De Pasquale, B, Di Raimo, P, Forte, E, Majetta, A, Vanuzzo, D, Feruglio, G, Pilotto, L, Cignacco, G, Marini, R, Zilio, G, Cesana, G, Ferrario, M, Sega, R, Mocarelli, P, Brambilla, P, Bluzhas, J, Domarkiene, S, Tamosiunas, A, Reklaitiene, R, Beaglehole, R, Jackson, R, Bonita, R, Stewart, A, Mahon, V, Bingley, W, Pajak, A, Sznajd, J, Kawalec, E, Pazucha, T, Malczewska, M, Mo ́rawska, I, Rywik, S, Broda, V, Polakowska, M, Kurjata, P, Varlamova, A, Britov, A, Konstantinov, V, Timofeeva, V, Alexandri, V, Konstantinova, O, Nikitin, Y, Malyutina, S, Gafarov, V, Feigin, V, Sans, S, Balaguer Vintro ́, V, Balana`, V, Gonzalez, V, Gomez, V, Borras, V, Rode ́s, A, Wilhelmsen, L, Harmsen, P, Rosengren, A, Lappas, G, Asplund, K, Huhtasaari, F, Stegmayr, B, Lundberg, V, Gutzwiller, F, Paccaud, F, Rickenbach, M, Wietlisbach, V, Barazzoni, F, Mainieri, F, Tullen, B, Evans, V, Mccrum, E, Falconer, T, Cashman, S, Patterson, C, Kerr, M, O’Reilly, D, Scott, A, Mcconville, M, Mcmillan, I, Mcmaster, D, Tunstall Pedoe, H, Smith, W, Tavendale, R, Crombie, V, Barrett, K, Brown, C, Shewry, M, Hannh, M, Morrisson, C, Planojevic, M, Jakovljevic, D, Svircevic, A, Mirilov, V, Strasser, V, Mendis, S, Martin8, I, Gyarfas8, V, Pı ́_sa8, V, Dodu8, S, Bo ̈thig8, S, Watson, M, Hill, M, Price, A, Kuulasmaa, K, Ruokokoski, E, Rajakangas, A, Ma ̈kinen, M, Virman Ojanen, T, Palonen, L, Akkila, J, Cepaitis, Z, Molarius, A, Moltchanov, V, Tolonen, H, Dobson, A, Fortmann, S, Shatchkute, A, Zaitsev, V, Epstein, F, Feinleib, M, Karvonen, M, Prineas, R, Williams, O, Hobbs, MST, Jamrozik, K., Thompson, PL, Armstrong, BK, Van Parys, L., Berghmans, L., Kulbertus, HE, Lefebvre, F., Wunsch, G., Bertrand, F., van Houte, M., Rime, B., Hannot, R., Wolf, HK, Gregor, RD, Bata, IR, Brownell, B., Pisa, Z., Berka, L., Cicha, Z., Hronkova, M., Pikhartova ́, J., Grafnetter, D., Poledne, R., Vojtisek, P., Vorlicek, J., Sjøl, A., Puska, P., Vartiainen, E., Korhonen, H., Richard, JL, Bingham, A., Cottel, D., Nuttens, MC, Marecaux, N., Dallongeville, J., Salomez, J. L., Montaye, M., Lamamy, N., Houset, M., Pierau, F., Ruidavets, JB, Cambou, JP, Rodier, P., Greiser, E., Herman, B., Nu ̈ssel, E., Osto ̈r Lamm, E., Scheidt, R., Morgenstern, W., Tietze, M., Banos, R., Do ̈ring, A., Muche, J., Schmalfuss, S., Assmann, A., Bo ̈thig, S., Voigt, G., Brasche, S., Quietzsch, D., Gudmundsdo ́ttir, II, Thorsteinsson, T., Sigvaldason H, Giampaoli, S., Righetti, G., De Pasquale, B., Forte, E., Feruglio, GA, Pilotto, L., Cignacco, G., Marini, R., Cesana, GC, Sega, R., BRAMBILLA, PAOLO, Domarkiene, S., Tamosiunas, A., Stewart, A., Kawalec, E., Pazucha, T., Malczewska, M., Rywik, SL, Broda,V, Polakowska, M., Britov, A., Nikitin, Y.u. P, Malyutina, S., Sans, S., Harmsen, P., Rosengren, A., Asplund, K., Huhtasaari, F., Stegmayr, B., Lundberg V, Paccaud, F., Rickenbach, M., Wietlisbach, V., Mainieri, F., McCrum, EE, Cashman, S., Patterson, C., Kerr, M., O’Reilly, D., Scott, A., McConville, M., McMillan, I., McMaster, D, Tunstall Pedoe, H., Smith, WCS, Tavendale, R., Barrett, K., Brown, C., Shewry, M., Hannh, M. K, Jakovljevic, D., Svircevic, A., Mirilov, V., Strasser, V., Mendis, S., Dodu8, S. R. A., Bo ̈thig8, S., Watson, M. J., Hill, M., Kuulasmaa, K., Tuomilehto, J., Rajakangas, A. M., Ma ̈kinen, M., Palonen, L., Cepaitis, Z., Molarius, A., Moltchanov, V., Dobson, A., Fortmann, SP, Epstein, FH, Karvonen, MJ, Prineas, RJ, and Williams, OD
- Abstract
Background and aims: The association between adiposity measures and dyslipidemia has seldom been assessed in a multipopulational setting. Methods and results: 27 populations from Europe, Australia, New Zealand and Canada (WHO MONICA project) using health surveys conducted between 1990 and 1997 in adults aged 35-64 years (n = 40,480). Dyslipidemia was defined as the total/HDL cholesterol ratio >6 (men) and >5 (women).Overall prevalence of dyslipidemia was 25% in men and 23% in women. Logistic regression showed that dyslipidemia was strongly associated with body mass index (BMI) in men and with waist circumference (WC) in women, after adjusting for region, age and smoking. Among normal-weight men and women (BMI<25 kg/m2), an increase in the odds for being dyslipidemic was observed between lowest and highest WC quartiles (OR = 3.6, p < 0.001). Among obese men (BMI ≥ 30), the corresponding increase was smaller (OR = 1.2, p = 0.036). A similar weakening was observed among women. Classification tree analysis was performed to assign subjects into classes of risk for dyslipidemia. BMI thresholds (25.4 and 29.2 kg/m2) in men and WC thresholds (81.7 and 92.6 cm) in women came out at first stages. High WC (>84.8 cm) in normal-weight men, menopause in women and regular smoking further defined subgroups at increased risk. Conclusion: standard categories of BMI and WC, or their combinations, do not lead to optimal risk stratification for dyslipidemia in middle-age adults. Sex-specific adaptations are necessary, in particular by taking into account abdominal obesity in normal-weight men, post-menopausal age in women and regular smoking in both sexes
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- 2013
9. Mo-P6:405 Familial defective apolipoprotein B-100 in Poland - high prevalence of APOB ARG3500GLN mutation
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Bednarska-Makaruk, M., primary, Broda, G., additional, Rywik, S., additional, and Wehr, H., additional
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- 2006
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10. Alcohol consumption and serum concentration of high sensitivity C-reactive protein in general Polish population
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Broda, G., primary, Kurjata, P., additional, Drygas, W., additional, Guszek, J., additional, Kozakiewicz, K., additional, Pajak, A., additional, Zdrojewski, T., additional, and Rywik, S., additional
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- 2005
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11. HYPERTENSION PREVALENCE AND ITS CONTROL IN A PRIMARY CARE POPULATION IN POLAND 2002-2003. POLSCREEN PROJECT
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Broda, G., primary, Cieslinski, A., additional, Rywik, S., additional, Adamus, J., additional, Szostak, W., additional, and Rynkiewicz, A., additional
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- 2004
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12. PULSE PRESSURE AND ITS DETERMINANTS IN A PRIMARY CARE POPULATION IN N POLAND 2002-2003. POLSCREEN PROJECT
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Broda, G., primary, Cieslinski, A., additional, Rywik, S., additional, Adamus, J., additional, Szostak, W., additional, and Rynkiewicz, A., additional
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- 2004
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13. HIGH STRESS LEVEL IN WARSAW POL-MONICA POPULATION IN RELATION TO HYPERTENSION AND TO CORONARY ARTERY DISEASE
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Piwonski, J., primary, Pytlak, A., additional, Piotrowski, W., additional, and Rywik, S., additional
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- 2004
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14. LOW SOCIAL SUPPORT LEVEL IN WARSAW POPULATION IN RELATION TO HYPERTENSION DURING THE POLISH SOCIO-ECONOMIC TRANSFORMATION
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Piwonski, J., primary, Piotrowski, W., additional, Pytlak, A., additional, and Rywik, S., additional
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- 2004
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15. Management of heart failure patients in Poland
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Korewicki, J., primary, Rywik, S., additional, and Rywik, T., additional
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- 2002
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16. 2.P.242 Is antithrombin III a risk factor for ischaemic heart disease (IHD) in Warsaw Pol-Monica population?
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Pytlak, A., primary, Piotrowski, W., additional, and Rywik, S., additional
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- 1997
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17. Sex Difference in High Density Lipoprotein Cholesterol in Six Countries
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Davis, C. E., primary, Williams, D. H., additional, Oganov, R. G., additional, Tao, S.-C., additional, Rywik, S. L, additional, Stein, Y., additional, and Little, J. A., additional
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- 1996
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18. Relation of triglycerides and lipoprotein cholesterol concentration to incidence of coronary heart disease (Pol-Monica Warsaw project)
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Broda, G., primary, Rywik, S., additional, and Szczesgniewska, D., additional
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- 1995
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19. Fluvastatin (Sandoz compound XU 62-320- lescol), an HMG-CoA reductase inhibitor, in treatment of patients with type II a hyperlipidemia — Its efficacy and safety
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Rywik, S., primary, Klosiewicz-Latoszek, U., additional, Broda, G., additional, and Szostak, W.B., additional
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- 1995
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20. Heart failure in patients seeking medical help at outpatients clinics. Part I. General characteristics.
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Rywik, Stefan L., Wągrowska, Henryka, Broda, Grażyna, Sarnecka, Aleksandra, Pytlak, Aleksandra, Polakowska, Maria, Drewla, Joanna, Korewicki, Jerzy, Rywik, S L, Wagrowska, H, Broda, G, Sarnecka, A, Pytlak, A, Polakowska, M, Drewla, J, and Korewicki, J
- Subjects
HEART failure ,DISEASE prevalence ,MEDICAL care for older people ,SYMPTOMS ,CORONARY disease ,HYPERTENSION ,ARRHYTHMIA ,X-rays ,DIAGNOSIS ,HYPERTENSION epidemiology ,ATTRIBUTION (Social psychology) ,OUTPATIENT services in hospitals ,CROSS-sectional method ,PATIENTS' attitudes - Abstract
Background: During the last decade, the beneficial changes in lifestyle and in medical care increased average life expectancy, particularly in patients with chronic diseases such as hypertension and coronary heart disease. Unfortunately this also increased the number of patients, particularly among the elderly, who are susceptible to complications of these conditions such as heart failure. Uncontrolled hypertension is known to be a primary cause of heart failure and is also known to be very prevalent and frequently uncontrolled in the Polish population.Aim: To estimate the prevalence and characteristics of heart failure among patients of 65 years and older seeking medical care in outpatient clinics in Poland.Methods: The study is a cross-country epidemiological project in which 417 physicians from outpatient clinics were asked to register 50 consecutive patients aged 65 years and above seeking medical care for any cause. Information on case history, physical examination (diagnosis of heart failure, NYHA class, heart failure symptoms), laboratory tests (resting ECG, chest X-ray, echocardiogram) and data concerning pharmacology management during the 2 weeks prior to the index visit was obtained.Results: Over 5 months, 19877 eligible patients (7324 men and 12553 women) presented to the 417 participating physicians (90% physicians registered 46-50 patients). Among the patients, 53% were diagnosed with heart failure (3901 men and 6678 women), prevalence did not differ by gender. Among patients with heart failure there were 38% of men in NYHA class III or IV and 34% of women. Coronary heart disease was a predominant cause of heart failure in 87% of men (26% of cases with isolated coronary heart disease, 53% with concomitant hypertension and 8% with other diseases), while percentages for women were 80% (15%, 61% and 4%, respectively). Isolated hypertension was a further cause of heart failure in 8% of men and 13% of women. Cardiac arrhythmia was found in approximately 20% of patients, enlargement of heart size in 32% of patients and peripheral leg edema in 54% of men and 64% of women. These symptoms increased with age. Chest X-ray revealed cardiomegaly in 68% of men and women and increased cardiothoracic ratio (>50%) in approximately 40% of patients. From resting ECGs, cardiac arrhythmia was recorded in 21% of patients with heart failure, with atrial fibrillation as a predominant disorder (19%). Left ventricular hypertrophy on resting ECG was noted in 42% of men and women and old myocardial infarction or cardiac ischemia was diagnosed in 71% of men and 66% of women.Conclusions: (1) Heart failure was diagnosed in over half of outpatients aged 65 and older; in more than a third of these it was NYHA class III and IV. (2) Outpatients with heart failure had a high frequency of co-existing diseases such as arrhythmia, coronary heart disease and hypertension. [ABSTRACT FROM AUTHOR]- Published
- 2000
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21. Incidence and correlates of hypertension in the Atherosclerosis Risk in Communities (ARIC) study and the Monitoring Trends and Determinants of Cardiovascular Disease (POL-MONICA) project.
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Rywik, Stefan L., Williams, O Dale, Pajak, Andrzej, Broda, Grazyna, Davis, Clarence E., Kawalec, Ewa, Manolio, Teri A., Piotrowski, Walerian, Hutchinson, Richard, Rywik, S L, Williams, O D, Pajak, A, Broda, G, Davis, C E, Kawalec, E, Manolio, T A, Piotrowski, W, and Hutchinson, R
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- 2000
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22. Opposing national stroke mortality trends in Poland and for African Americans and whites in the United States, 1968 to 1994.
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Massing, M W, Rywik, S L, Jasinski, B, Manolio, T A, Williams, O D, and Tyroler, H A
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- 1998
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23. Mortality, morbidity and case fatality from myocardial infarction and the cardiovascular risk profile in the Warsaw population.
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RYWIK, S., KUPŚĆ, W., WĄGROWSKA, H., KULESZA, W., BRODA, G., and POLAKOWSKA, M.
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- 1988
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24. Constitutional, biochemical and lifestyle correlates of fibrinogen and factor VII activity in Polish urban and rural populations.
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Pajak, A, Broda, G, Manolio, TA, Kawalec, E, Rywik, S, Davis, CE, Pikon, J, Pytlak, A, Thomas, RP, Manolio, T A, Davis, C E, and Thomas, R P
- Abstract
Background: Fibrinogen and factor VII activity are known to be related to atherosclerosis and coronary heart disease, but population differences in clotting factors and modifiable characteristics that influence their levels have not been widely explored.Methods: This paper examines correlates of plasma fibrinogen concentration and factor VII activity in 2443 men and women aged 35-64 in random samples selected from the residents in two districts in urban Warsaw (618 men and 651 women) and from rural Tarnobrzeg Province (556 men and 618 women) screened in 1987-1988, and assesses which characteristics might explain urban-rural differences. Fibrinogen and factor VII activity were determined using coagulation methods.Results: Fibrinogen was 12.9 mg/dl higher in men and 14.1 mg/dl higher in women in Tarnobrzeg compared to Warsaw. Factor VII activity was higher in Warsaw (9.2% in men and 15.3% in women). After adjustment for selected characteristics, fibrinogen was higher in smokers compared to non-smokers by 28 mg/dl in men and 22 mg/dl in women. In women, a 15 mg/dl increase in HDL-cholesterol was associated with a 10 mg/dl decrease in fibrinogen (P < 0.01). After adjustment for other variables, a higher factor VII activity in Warsaw remained significant (a difference of 9.4% in men and 14.8% in women). Lower fibrinogen in Warsaw remained significant only in women (15.4 mg/dl difference).Conclusions: The study confirmed that sex, age, BMI, smoking and blood lipids are related to clotting factors. However, with the exception of gender differences and smoking, associations between clotting factors and other variables were small and of questionable practical importance. [ABSTRACT FROM AUTHOR]- Published
- 1998
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25. Prevalence of diabetes mellitus, coronary heart disease and hypertension in the families of insulin dependent and insulin independent diabetics
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Andrzej S. Krolewski, Rywik S, Kopczyński J, and Czyzyk A
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Adult ,Male ,Proband ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,medicine.medical_treatment ,Population ,Coronary Disease ,Close relatives ,Internal medicine ,Diabetes mellitus ,Epidemiology ,Diabetes Mellitus ,Internal Medicine ,medicine ,Humans ,Insulin ,Obesity ,education ,Aged ,education.field_of_study ,business.industry ,Age Factors ,Middle Aged ,medicine.disease ,Coronary heart disease ,Endocrinology ,Hypertension ,Female ,business ,Insulin dependent - Abstract
During an epidemiological study concerning the fate of diabetics in Warsaw, 2,356 subjects (aged 35–68 years with duration of diabetes mellitus of 3–11 years) were investigated with particular relevance to the presence of diabetes mellitus, coronary heart disease, and hypertension in their parents and siblings. Diabetics were classified into the following groups: insulin dependent, insulin independent nonobese, insulin independent obese, and a group in whom the distinction between insulin dependence and insulin independence was unclear. The findings in these groups were compared with the frequencies of these diseases in a random sample of the general population. There was an excess of diabetes in close relatives of all the diabetic groups. This was highest for insulin independent non-obese diabetics. There was no difference in the prevalence of coronary heart disease and hypertension in close relatives of insulin dependent diabetics when compared with the general population, but these were twice as prevalent in close relatives of the insulin independent non-obese group. Obese insulin independent diabetics reported a similar excess of coronary heart disease and hypertension in siblings, but the excess was less marked in parents. The prevalence of these diseases in families of probands with unclassified diabetes was intermediate between the other two groups. These results demonstrate an aggregation of diabetes mellitus with coronary heart disease and hypertension in families of insulin independent non-obese diabetics. This provides further evidence for heterogeneity in diabetes mellitus.
- Published
- 1981
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26. Poland and U.S. Collaborative Study on Cardiovascular Epidemiology Hypertension in the Community: Prevalence, Awareness, Treatment, and Control of Hypertension in the Pol-MONICA Project and the U.S. Atherosclerosis Risk in Communities Study
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Rywik, S. L., Davis, C. E., Pajak, A., Broda, G., Folsom, A. R., Kawalec, E., and Williams, O. D.
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- 1998
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27. Changes over Time in Blood Lipids and Their Correlates in Polish Rural and Urban Populations: The Poland-United States Collaborative Study in Cardiopulmonary Disease Epidemiology
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Pajak, A., Williams, O. D., Broda, G., Baczynska, E., Rywik, S., Davis, C. E., Kawalec, E., Chodkowska, E., Irving, S., and Manolio, T.
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- 1997
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28. Poland and US collaborative study on cardiovascular epidemiology. I. Introduction and baseline findings.
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Rywik, S, Sznajd, J, Williams, O D, Pajak, A, Przestalska-Malkin, H, Thomas, R P, Kupsc, W, Misiowiec, P, Irving, S H, and Magdon, M
- Abstract
The Poland-US Agreement for Health Cooperation has as its goal the sharing of scientific information in cardiovascular disease epidemiology between the two countries. Patterns of cardiovascular disease and identification of risk factors were investigated through two large epidemiologic studies, the Pol-Monica Study in Poland and the US Lipid Research Clinics Program Prevalence Study in the United States. These two studies are described with regard to methodological issues, comparability of data collection procedures, and demographic and behavioral characteristics of the two populations involved. Mean blood pressure, lipids, and body mass indices of participants in these studies are also compared.
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- 1989
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29. Poland and US collaborative study on cardiovascular epidemiology. II. Correlates of lipids and lipoproteins in men and women aged 35-64 years from selected Polish rural, Polish urban, and US samples.
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Sznajd, J, Rywik, S, Furberg, B, Pajak, A, Kurjata, P, Williams, O D, Sznajderman-Ciswicka, M, Misiowiec, P, Irving, S H, and Baczynska, E
- Abstract
Three diverse samples of men and women aged 35-64 years living in urban Poland, rural Poland, and the United States, are described and subsequently analyzed by multiple regression methods. Total cholesterol, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol, and the natural logarithm (ln) of triglycerides are treated separately as dependent variables, with several demographic, behavioral, and biologic factors as independent variables. In the analyses of total cholesterol, systolic blood pressure was statistically significant in men and women in all three samples, while Quetelet index, cigarette smoking, age, ethanol consumption, and education were significant in at least one of the samples. In the LDL cholesterol analyses, Quetelet index and cigarette smoking were the predominant variables; in the HDL cholesterol analyses, Quetelet index, cigarette smoking, ethanol consumption, and age were key variables; and in the ln triglycerides analyses, Quetelet index, cigarette smoking, education, and systolic blood pressure were significant.
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- 1989
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30. Poland and US collaborative study on cardiovascular epidemiology. III. Correlates of systolic and diastolic blood pressure in men and women aged 35-64 years from selected Polish rural, Polish urban, and US samples.
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Williams, O D, Rywik, S, Sznajd, J, Abernathy, J R, Pajak, A, Kupsc, W, Furberg, B, Broda, G, Celinski, A, and Thomas, R P
- Abstract
Three diverse samples of men and women aged 35-64 years living in urban Poland, rural Poland, and the United States are described and subsequently analyzed using systolic blood pressure and diastolic blood pressure separately as dependent variables in multiple regression. Several demographic, behavioral, and biologic factors are included in the models as independent variables. Heart rate, Quetelet index, high density lipoprotein cholesterol, and the natural logarithm of triglycerides were statistically significant in accounting for variation in systolic pressure in men in all three samples, whereas only heart rate and Quetelet index were significant in women in all samples. In the analysis of diastolic pressure, Quetelet index, heart rate, and ethanol consumption were statistically significant in men in all three samples, while only Quetelet index and heart rate were significant in women in all samples.
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- 1989
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31. M.472 Cholesterol screening in a primary care population in Poland 2002–2003. Polscreen project
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Broda, G., Rywik, S., Kurjata, P., Pytlak, A., and Rynkiewicz, A.
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- 2004
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32. National, multicenter cardiovascular diseases prevention program - Polish 400 Cities Project. Basic assumptions, objectives, execution,Ogólnopolski, wieloośrodkowy program profilaktyki chorób układu krażenia - Polski Projekt 400 Miast. Główne założenia, cele oraz sposób realizacji
- Author
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Zdrojewski, T., Rutkowski, M., Marzena Zarzeczna-Baran, Grodzicki, T., Januszewicz, A., Narkiewicz, K., Głuszek, J., Drygas, W., Zatoónski, W., Wyrzykowski, B., Wierucki, Ł., Popowski, P., Medraś, M., Bautembach, S., Makarewicz, W., Wizner, B., Słonska, Z., Piwoński, J., Tykarski, A., Opolski, G., Jarosz, M., Szczech, R., Mogilnaya, I., Szyndler, A., Chwojnicki, K., Kakol, K., Semetkowska-Jurkiewicz, E., Rachoń, K., Jedrzejczyk, T., Wojdak, E., Wołowski, T., Pegiel-Kamrat, J., Nowalińska, M., Gronek, B., Bonarski, Z., Wojtecka, A., Kozłoska-Wojciechowska, M., Szponar, L., Posadzy-Małaczyńska, A., Zagozdzon, P., Kabat, M., Prejbisz, A., Piotrowski, W., Jegier, A., Kostka, T., Przewoźniak, K., Cedzyńska, M., Szczepaniak, P., Światek, I., Koczurowski, K., Wojciszke, B., Baryła, W., Konarska, M., Kawalec, W., Łysiak-Szydłowska, W., Ryglewicz, D., Członkowska, A., Religa, Z., Tendera, M., Cieśliński, A., Krupa-Wojciechowska, B., Rywik, S., and Szostak, W.
33. A comparative analysis of the spectrum of blood lipoproteins in random population samples
- Author
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Perova, N. V., Rywik, S., Sznajd, J., Nikitin, Y. P., Smirnova, I. P., Broda, G., Burlutskii, G. I., Varlamova, T. A., Voevoda, M. S., Wagrowska, H., Dvorkin, V. I., Zhukovskii, G. S., Vladimir KONSTANTINOV, Nowacki, G., Myslowiec, P., Oganov, R. G., Olferev, A. M., Pajak, A., and Polakowska, M.
34. Epidemiology of Cardiovascular Diseases in Warsaw PoI-MONICA Area
- Author
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Rywik, S., primary, Wagrowska, H., additional, Broda, G., additional, Kuzminska, A., additional, Polakowska, M., additional, Kulesza, W., additional, Kupsc, W., additional, and Kurjata, P., additional
- Published
- 1989
- Full Text
- View/download PDF
35. Association of lipids and lipoprotein level with total mortality and mortality caused by cardiovascular and cancer diseases (Poland and United States collaborative study on cardiovascular epidemiology).
- Author
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Rywik, Stefan L., Manolio, Teri A., Rywik, S L, Manolio, T A, Pajak, A, Piotrowski, W, Davis, C E, Broda, G B, and Kawalec, E
- Subjects
- *
CHOLESTEROL , *TRIGLYCERIDES , *HIGH density lipoproteins , *HEALTH ,CARDIOVASCULAR disease related mortality - Abstract
This study evaluates the relation between total serum cholesterol, triglycerides, and high-density lipoprotein (HDL) cholesterol, and subsequent total, cardiovascular, and cancer mortality. These data are from 4,946 US and 5,198 Polish men and women aged 35 to 64 years at baseline with mortality follow-up over 13 years. Total cholesterol showed a U-shaped or J-shaped relation to age-adjusted total and cancer mortality across all samples, with significance only in Polish women. The multivariable adjusted relative risk for total and cancer mortality was higher in the lowest cholesterol category only in Poland and significant only for cancer. Cardiovascular mortality was positively related to cholesterol, but only in Polish men and US women was mortality significantly higher in the highest versus the lowest cholesterol category. The multivariable adjusted relative risk of cardiovascular death was greater in the highest versus the lowest cholesterol category, but this trend was significant only in the US. HDL cholesterol was inversely related to total (significant only in US men) and cardiovascular mortality (significant only in US and Polish men). A similar, but not significant, association of HDL cholesterol was found with cancer mortality. The multivariable adjusted relative risk of total mortality was inversely related to HDL cholesterol significant in both the US and Poland. The relative risk of cardiovascular mortality was significantly lower at higher HDL cholesterol levels in all samples. The relative risk of cancer mortality was highest and significant at the lowest HDL cholesterol level in the US and Poland. Elevated triglycerides were associated with increased risk of total and cardiovascular mortality, but this trend was significant only in the US. Cancer mortality was not significantly related to triglycerides. The present study indicates that in geographically and culturally diverse populations, the relation of lipids with cardiovascular mortality is similar. The relation with total and cancer mortality varies by country, gender, and lipids. This suggests that relations of total and cancer mortality with lipids or lipoproteins are weaker than associations with cardiovascular mortality. [ABSTRACT FROM AUTHOR]
- Published
- 1999
- Full Text
- View/download PDF
36. Comparison of medical care and survival of hospitalized patients with acute myocardial infarction in Poland and the United States.
- Author
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Rosamond, Wayne, Broda, Grazyna, Rosamond, W, Broda, G, Kawalec, E, Rywik, S, Pajak, A, Cooper, L, and Chambless, L
- Subjects
- *
MEDICAL care , *MYOCARDIAL infarction treatment - Abstract
Few studies have evaluated between-country differences in medical care and survival after acute myocardial infarction, and none have compared the US with countries from Eastern Europe. Comparable data from the US (Atherosclerosis Risk in Communities Study [US-ARIC]) and Poland (Multinational Monitoring of Trends and Determinants in Cardiovascular Disease project [Pol-MONICA]) were developed. From 1987 through 1993, a total of 3,694 patients were hospitalized with acute myocardial infarction events in the 2 Pol-MONICA communities and 4,801 in the 4 US-ARIC communities. Patients in the US-ARIC were 1.7 times more likely to be treated in a coronary care unit and received cardiac procedures, calcium channel blockers, and thrombolytic agents significantly more often than patients in the Pol-MONICA. The use of antiplatelet agents, nitrates, angiotensin-converting enzyme inhibitors, and beta blockade agents was similar in both countries. Case fatality (28-day) rates after hospitalized acute myocardial infarction were nearly identical (men, 7% in Pol-MONICA vs 6% in US-ARIC; women, 9% in Pol-MONICA vs 8% in US-ARIC). However, when fatal coronary heart disease events not associated with a hospitalized myocardial infarction were included, the US-ARIC rates were less than half than those seen in Pol-MONICA. Substantial differences in treatment of hospitalized acute myocardial infarction between countries did not translate into a survival advantage for patients reaching clinical attention. Differences in case severity, arising from the high out-of-hospital coronary death rate in Poland may play an important role in this finding. [ABSTRACT FROM AUTHOR]
- Published
- 1999
- Full Text
- View/download PDF
37. The relation of body mass index and abdominal adiposity with dyslipidemia in 27 general populations of the WHO MONICA Project
- Author
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Hobbs, MST, Jamrozik, K., Thompson, PL, Armstrong, BK, de Backer, G, De Craene, I, Van Onsem, P, Van Parys, L., De Henauw, S, De Bacquer, D, Kornitzer, M, Berghmans, L., Bara, L, de Smet, P, Jeanjean, M, Brohet, C, Kulbertus, HE, Degre, S, Lavenne, F, Jansens, D, Lefebvre, F., Beck, D, Wunsch, G., Bertrand, F., van Houte, M., Rime, B., Rorive, G, Hannot, R., Adrienne, A, Luyckx, A, Wolf, HK, Gregor, RD, Bata, IR, Brownell, B., Webber, K, Skodova´, Z, Pisa, Z., Berka, L., Cicha, Z., Cerovska´, J, Emrova´, R, Hoke, M, Hronkova, M., Pikhartova´, J., Grafnetter, D., Poledne, R., Vojtisek, P., Vorlicek, J., Wiesner, E, Schroll, M, Kirchhoff, M, Sjøl, A., Quitsau Lund, S, Tuomilehto, J, Puska, P., Vartiainen, E., Korhonen, H., Jousilahti, M, Ducimetie`re, P, Richard, JL, Bingham, A., Lang, T, Amouyel, P, Cottel, D., Nuttens, MC, Marecaux, N., Dallongeville, J., Salomez, J. L., Montaye, M., Steclebout, C, Arveiler, D, Schaffer, P, Haas, V, Wagner, A, Lamamy, N., Savouret, M, Houset, M., Pierau, F., Goetz, V, Ferrie`res, J, Ruidavets, JB, Cambou, JP, Rodier, P., Saulet, C, Greiser, E., Herman, B., Stu¨demann, G, Nu¨ssel, E., Osto¨r Lamm, E., Scheidt, R., Morgenstern, W., Stadler, M, Ganova, M, Keil, U, Tietze, M., Banos, R., Do¨ring, A., Filipiak, B, Barth, W, Heinemann, L, Muche, J., Schmalfuss, S., Assmann, A., Bo¨thig, S., Voigt, G., Brasche, S., Quietzsch, D., Classen, E, Sigfu´sson, N, Gudmundsdo´ttir, II, Stefa´nsdo´ttir, I, Thorsteinsson, T., Sigvaldason H, Menotti, A, Giampaoli, S., Verdecchia, A, Righetti, G., De Pasquale, B., Di Raimo, P, Forte, E., Majetta, A, Vanuzzo, D, Feruglio, GA, Pilotto, L., Cignacco, G., Marini, R., Zilio, G, Cesana, GC, Ferrario, M, Sega, R., Mocarelli, P, BRAMBILLA, PAOLO, Bluzhas, J, Domarkiene, S., Tamosiunas, A., Reklaitiene, R, Beaglehole, R, Jackson, R, Bonita, R, Stewart, A., Mahon, V, Bingley, W, Pajak, A, Sznajd, J, Kawalec, E., Pazucha, T., Malczewska, M., Mo´rawska, I, Rywik, SL, Broda,V, Polakowska, M., Kurjata, P, Varlamova, A, Britov, A., Konstantinov, V, Timofeeva, V, Alexandri, V, Konstantinova, O, Nikitin, Y.u. P, Malyutina, S., Gafarov, V, Feigin, V, Sans, S., Balaguer Vintro´, V, Balana`, V, Gonzalez, V, Gomez, V, Borras, V, Rode´s, A, Wilhelmsen, L, Harmsen, P., Rosengren, A., Lappas, G, Asplund, K., Huhtasaari, F., Stegmayr, B., Lundberg V, Gutzwiller, F, Paccaud, F., Rickenbach, M., Wietlisbach, V., Barazzoni, F, Mainieri, F., Tullen, B, Evans, V, McCrum, EE, Falconer, T, Cashman, S., Patterson, C., Kerr, M., O’Reilly, D., Scott, A., McConville, M., McMillan, I., McMaster, D, Tunstall Pedoe, H., Smith, WCS, Tavendale, R., Crombie, V, Barrett, K., Brown, C., Shewry, M., Hannh, M. K, Morrisson, C, Planojevic, M, Jakovljevic, D., Svircevic, A., Mirilov, V., Strasser, V., Mendis, S., Martin8, I, Gyarfas8, V, Pı´_sa8, V, Dodu8, S. R. A., Bo¨thig8, S., Watson, M. J., Hill, M., Price, A, Kuulasmaa, K., Tuomilehto, J., Ruokokoski, E, Rajakangas, A. M., Ma¨kinen, M., Virman Ojanen, T, Palonen, L., Akkila, J, Cepaitis, Z., Molarius, A., Moltchanov, V., Tolonen, H, Grafnetter, D, Dobson, A., Fortmann, SP, Shatchkute, A, Zaitsev, V, Epstein, FH, Feinleib, M, Karvonen, MJ, Prineas, RJ, Williams, OD, Hobbs, M, Jamrozik, K, Thompson, P, Armstrong, B, de Backer, G, De Craene, I, Van Onsem, P, Van Parys, L, De Henauw, S, De Bacquer, D, Kornitzer, M, Berghmans, L, Bara, L, de Smet, P, Jeanjean, M, Brohet, C, Kulbertus, H, Degre, S, Lavenne, F, Jansens, D, Lefebvre, F, Beck, D, Wunsch, G, Bertrand, F, van Houte, M, Rime, B, Rorive, G, Hannot, R, Adrienne, A, Luyckx, A, Wolf, H, Gregor, R, Bata, I, Brownell, B, Webber, K, Skodova´, Z, Pisa, Z, Berka, L, Cicha, Z, Cerovska´, J, Emrova´, R, Hoke, M, Hronkova, M, Pikhartova´, J, Grafnetter, D, Poledne, R, Vojtisek, P, Vorlicek, J, Wiesner, E, Schroll, M, Kirchhoff, M, Sjøl, A, Quitsau Lund, S, Tuomilehto, J, Puska, P, Vartiainen, E, Korhonen, H, Jousilahti, M, Ducimetie`re, P, Richard, J, Bingham, A, Lang, T, Amouyel, P, Cottel, D, Nuttens, M, Marecaux, N, Dallongeville, J, Salomez, J, Montaye, M, Steclebout, C, Arveiler, D, Schaffer, P, Haas, V, Wagner, A, Lamamy, N, Savouret, M, Houset, M, Pierau, F, Goetz, V, Ferrie`res, J, Ruidavets, J, Cambou, J, Rodier, P, Saulet, C, Greiser, E, Herman, B, Stu¨demann, G, Nu¨ssel, E, Osto¨r Lamm, E, Scheidt, R, Morgenstern, W, Stadler, M, Ganova, M, Keil, U, Tietze, M, Banos, R, Do¨ring, A, Filipiak, B, Barth, W, Heinemann, L, Muche, J, Schmalfuss, S, Assmann, A, Bo¨thig, S, Voigt, G, Brasche, S, Quietzsch, D, Classen, E, Sigfu´sson, N, Gudmundsdo´ttir, I, Stefa´nsdo´ttir, I, Thorsteinsson, T, Sigvaldason, H, Menotti, A, Giampaoli, S, Verdecchia, A, Righetti, G, De Pasquale, B, Di Raimo, P, Forte, E, Majetta, A, Vanuzzo, D, Feruglio, G, Pilotto, L, Cignacco, G, Marini, R, Zilio, G, Cesana, G, Ferrario, M, Sega, R, Mocarelli, P, Brambilla, P, Bluzhas, J, Domarkiene, S, Tamosiunas, A, Reklaitiene, R, Beaglehole, R, Jackson, R, Bonita, R, Stewart, A, Mahon, V, Bingley, W, Pajak, A, Sznajd, J, Kawalec, E, Pazucha, T, Malczewska, M, Mo´rawska, I, Rywik, S, Broda, V, Polakowska, M, Kurjata, P, Varlamova, A, Britov, A, Konstantinov, V, Timofeeva, V, Alexandri, V, Konstantinova, O, Nikitin, Y, Malyutina, S, Gafarov, V, Feigin, V, Sans, S, Balaguer Vintro´, V, Balana`, V, Gonzalez, V, Gomez, V, Borras, V, Rode´s, A, Wilhelmsen, L, Harmsen, P, Rosengren, A, Lappas, G, Asplund, K, Huhtasaari, F, Stegmayr, B, Lundberg, V, Gutzwiller, F, Paccaud, F, Rickenbach, M, Wietlisbach, V, Barazzoni, F, Mainieri, F, Tullen, B, Evans, V, Mccrum, E, Falconer, T, Cashman, S, Patterson, C, Kerr, M, O’Reilly, D, Scott, A, Mcconville, M, Mcmillan, I, Mcmaster, D, Tunstall Pedoe, H, Smith, W, Tavendale, R, Crombie, V, Barrett, K, Brown, C, Shewry, M, Hannh, M, Morrisson, C, Planojevic, M, Jakovljevic, D, Svircevic, A, Mirilov, V, Strasser, V, Mendis, S, Martin8, I, Gyarfas8, V, Pı´_sa8, V, Dodu8, S, Bo¨thig8, S, Watson, M, Hill, M, Price, A, Kuulasmaa, K, Ruokokoski, E, Rajakangas, A, Ma¨kinen, M, Virman Ojanen, T, Palonen, L, Akkila, J, Cepaitis, Z, Molarius, A, Moltchanov, V, Tolonen, H, Dobson, A, Fortmann, S, Shatchkute, A, Zaitsev, V, Epstein, F, Feinleib, M, Karvonen, M, Prineas, R, and Williams, O
- Subjects
Adult ,Male ,Canada ,medicine.medical_specialty ,BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA ,Waist ,Cross-sectional study ,Endocrinology, Diabetes and Metabolism ,Medicine (miscellaneous) ,Logistic regression ,Body Mass Index ,Risk Factors ,Internal medicine ,Prevalence ,medicine ,Humans ,Triglycerides ,Abdominal obesity ,Adiposity ,Dyslipidemias ,Nutrition and Dietetics ,business.industry ,Cholesterol, HDL ,Smoking ,Australia ,nutritional and metabolic diseases ,Cholesterol, LDL ,Middle Aged ,medicine.disease ,Health Surveys ,Europe ,Menopause ,Cross-Sectional Studies ,Logistic Models ,Endocrinology ,Dyslipidemia ,Quartile ,Obesity, Abdominal ,Female ,Waist Circumference ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Body mass index ,New Zealand ,Demography - Abstract
Background and aims: The association between adiposity measures and dyslipidemia has seldom been assessed in a multipopulational setting. Methods and results: 27 populations from Europe, Australia, New Zealand and Canada (WHO MONICA project) using health surveys conducted between 1990 and 1997 in adults aged 35-64 years (n = 40,480). Dyslipidemia was defined as the total/HDL cholesterol ratio >6 (men) and >5 (women).Overall prevalence of dyslipidemia was 25% in men and 23% in women. Logistic regression showed that dyslipidemia was strongly associated with body mass index (BMI) in men and with waist circumference (WC) in women, after adjusting for region, age and smoking. Among normal-weight men and women (BMI84.8 cm) in normal-weight men, menopause in women and regular smoking further defined subgroups at increased risk. Conclusion: standard categories of BMI and WC, or their combinations, do not lead to optimal risk stratification for dyslipidemia in middle-age adults. Sex-specific adaptations are necessary, in particular by taking into account abdominal obesity in normal-weight men, post-menopausal age in women and regular smoking in both sexes
- Published
- 2013
- Full Text
- View/download PDF
38. Did favourable trends in food consumption observed in the 1984-2001 period contribute to the decrease in cardiovascular mortality? - Pol-MONICA Warsaw Project.
- Author
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Waśkiewicz A, Piotrowski W, Sygnowska E, Rywik S, and Jasiński B
- Subjects
- Adult, Cardiovascular Diseases epidemiology, Catchment Area, Health, Cross-Sectional Studies, Energy Intake, Humans, Incidence, Middle Aged, Poland epidemiology, Prevalence, Cardiovascular Diseases mortality, Cardiovascular Diseases prevention & control, Diet trends, Feeding Behavior
- Abstract
Aim: To compare food consumption trends (1984-2001) with cardiovascular mortality trends (1984-2002) in an adult population of right-bank Warsaw residents and establish the delay between dietary changes and mortality reduction., Methods: Cardiovascular mortality rates for the 1984-2002 period, calculated based on the Central Statistical Office data and the results of individual evaluation of nutrition patterns in 4 independent Pol-MONICA cross-sectional studies (1984, 1988, 1993 and 2001) were analysed., Results: The cardiovascular mortality rate in right-bank Warsaw inhabitants tended to increase until 1991, and then a decline was observed -- in 2002 in comparison to 1991 the mortality rate in both genders decreased by over 50%. From 1984 to 2001 a significant decrease in the following dietary factors was found: total energy intake, dietary cholesterol, and Keys score reflecting atherogenicity of the diet and animal fats. In contrast trends of vegetable fats intake increased. The favourable changes in the dietary habits of Warsaw inhabitants were correlated with the reduction of cardiovascular mortality (R2 within the range of 0.35-0.95), and the strongest relationship between these facts occurred after 7 years., Conclusions: A positive tendency observed with respect to nutrition patterns of right-bank Warsaw inhabitants contributed to the reduction of cardiovascular mortality.
- Published
- 2006
39. [Intake of consumed products by adults in the Polish population. Results of the WOBASZ program].
- Author
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Sygnowska E, Waśkiewicz A, Głuszek J, Kwaśniewska M, Biela U, Kozakiewicz K, Zdrojewski T, and Rywik S
- Subjects
- Adult, Age Distribution, Aged, Dietary Fats, Eating, Edible Grain supply & distribution, Female, Fish Products statistics & numerical data, Humans, Male, Meat Products statistics & numerical data, Middle Aged, Poland epidemiology, Population Surveillance, Seafood statistics & numerical data, Seasons, Young Adult, Economics statistics & numerical data, Food classification, Food Supply classification, Food Supply statistics & numerical data
- Published
- 2005
40. [Multicenter national Polish population health status tests--WOBASZ project with defined problems and treatment goals].
- Author
-
Broda G and Rywik S
- Subjects
- Adult, Aged, Cardiovascular Diseases prevention & control, Disease Outbreaks statistics & numerical data, Female, Humans, Male, Middle Aged, Multicenter Studies as Topic, Poland epidemiology, Program Development, Risk Factors, Survival Rate, World Health Organization, Young Adult, Cardiovascular Diseases epidemiology, Disease Outbreaks prevention & control, Health Status Indicators
- Published
- 2005
41. [Levels of homocysteine in blood serum--new coronary risk factors--in adult residents of our country. Results of the WOBASZ program].
- Author
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Tykarski A, Posadzy-Małaczyńska A, Rywik S, Jasiński B, Drygas W, Wyrzykowski B, Kozakiewicz K, and Pajak A
- Subjects
- Adult, Age Distribution, Aged, Coronary Disease blood, Coronary Disease epidemiology, Female, Humans, Male, Middle Aged, Poland epidemiology, Risk Factors, Sex Distribution, Young Adult, Homocysteine blood, Mass Screening statistics & numerical data
- Published
- 2005
42. [Addiction to tobacco smoking in the Polish population. Results of the WOBASZ program].
- Author
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Polakowska M, Piotrowski W, Tykarski A, Drygas W, Wyrzykowski B, Pajak A, Kozakiewicz K, and Rywik S
- Subjects
- Adult, Age Distribution, Aged, Comorbidity, Female, Humans, Male, Mass Spectrometry statistics & numerical data, Middle Aged, Poland epidemiology, Sex Distribution, Young Adult, Smoking epidemiology, Tobacco Use Disorder epidemiology
- Published
- 2005
43. [Evaluation of the incidence of low levels of social interaction and depressive symptoms in the Polish population. Results of the WOBASZ program].
- Author
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Piwoński J, Piwońska A, Głuszek J, Bielecki W, Pajak A, Kozakiewicz K, Wyrzykowski B, and Rywik S
- Subjects
- Adult, Age Distribution, Aged, Female, Humans, Male, Middle Aged, Poland epidemiology, Prevalence, Sex Distribution, Young Adult, Depression epidemiology, Social Alienation
- Published
- 2005
44. [Homocysteine level, relationship with cardiovascular risk factors in selected Polish population].
- Author
-
Sygnowska E, Rywik S, Pajak A, Waśkiewicz A, Janas J, and Gazdzik D
- Subjects
- Adult, Aged, Coronary Artery Disease prevention & control, Epidemiological Monitoring, Female, Folic Acid blood, Humans, Male, Middle Aged, Poland, Risk Factors, Smoking epidemiology, Vitamin B 12 blood, Vitamin B 6 blood, Vitamin B Complex blood, Environmental Monitoring statistics & numerical data, Health Status, Homocysteine blood, Life Style, Rural Population statistics & numerical data, Urban Population statistics & numerical data
- Abstract
The aim of the study was to evaluate the concentration and distribution of homocysteine in random samples of men and women aged 20-74 from two populations: urban (Warsaw) and industrial-rural (former Tarnobrzeg Province), and the estimation of relationship between selected cardiovascular risk factors and homocysteine concentration. In 2001 in 617 men and 657 women homocysteine level, lipids profile, glucose, folic acid, vitamin B12 concentration, blood pressure and alcohol intake were determined. The mean (geometric) homocysteine concentration was 10.9 micro mol/L in men and 9.6 micro mol/L in women. There were no differences in the homocysteine concentration and distribution between regions according to sex. The homocysteine level was connected with folic acid and vitamin B12 concentration in both genders. Moreover, in men was recorded relationship between homocysteine and body mass index, cholesterol level, alcohol intake, and in women between homocysteine and daily number of cigarettes smoked.
- Published
- 2005
45. [Prevalence of hypertension and effectiveness of its treatment in adult residents of our country. Results of the WOBASZ program].
- Author
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Tykarski A, Posadzy-Małaczyńska A, Wyrzykowski B, Kwaśniewska M, Pajak A, Tendera M, Rywik S, Broda G, and Zdrojewski T
- Subjects
- Adult, Age Distribution, Aged, Female, Humans, Hypertension diagnosis, Male, Middle Aged, Poland epidemiology, Prevalence, Program Evaluation, Young Adult, Hypertension epidemiology, Hypertension prevention & control, Mass Screening statistics & numerical data
- Published
- 2005
46. [Multicenter national Polish population health status tests--WOBASZ project. Establishment of methods and logistics].
- Author
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Rywik S, Kupść W, Piotrowski W, Broda G, Piwoński J, Kurjata P, Waśkiewicz A, and Gaździk D
- Subjects
- Diagnostic Techniques and Procedures, Humans, Multicenter Studies as Topic methods, Poland epidemiology, Population Surveillance methods, Surveys and Questionnaires, Health Status Indicators, Mass Screening organization & administration, Program Development methods
- Published
- 2005
47. Total cholesterol and mortality in China, Poland, Russia, and the US.
- Author
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Cai J, Pajak A, Li Y, Shestov D, Davis CE, Rywik S, Li Y, Deev A, and Tyroler HA
- Subjects
- Adult, Bayes Theorem, Biomarkers blood, Cardiovascular Diseases mortality, Cause of Death, China epidemiology, Cholesterol classification, Coronary Disease mortality, Female, Humans, Male, Middle Aged, Poland epidemiology, Proportional Hazards Models, Risk Assessment, Risk Factors, Russia epidemiology, United States epidemiology, Cholesterol blood, Mortality trends
- Abstract
Purpose: To examine the relationships of total and cause-specific mortality to serum cholesterol in four diverse populations., Methods: Chinese, Polish, Russian, and US population-based samples were studied. The relationship between cholesterol levels and mortality was assessed by Cox proportional hazard regression with restricted piecewise cubic splines., Results: The cholesterol and total mortality relationship was statistically significantly J-shaped for all men combined. In country-specific relationships, cholesterol was significantly, linearly, and positively related to total mortality in Russian and US men. For women, the relationship was non-linear, but not statistically significant, and became statistically significant upon adjustment for other risk factors. For Polish women, a statistically significant inverse relationship existed. CHD mortality and cardiovascular disease (CVD) mortality increased linearly with cholesterol in Polish, Russian, and US men and the aggregate of men, but there was no relationship for women. Cancer mortality was not related to cholesterol except for the Polish cohort and Russian women, where there was an inverse relationship., Conclusions: Serum cholesterol was a strong, consistent predictor of CHD and CVD mortality in Polish, Russian, and US men despite their social diversity. In contrast to CHD mortality, the relation of cholesterol to total mortality and non-CVD mortality varied by country and gender.
- Published
- 2004
- Full Text
- View/download PDF
48. [Epidemiology of arterial hypertension with emphasis on population studies conducted in Poland].
- Author
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Rywik S
- Subjects
- Adult, Age Distribution, Aged, Aged, 80 and over, Female, Humans, Hypertension prevention & control, Incidence, Male, Middle Aged, Poland epidemiology, Population Surveillance, Sex Distribution, Hypertension epidemiology
- Published
- 2001
49. [Total serum cholesterol and cholesterol lipoprotein fractions in random sample of Warsaw population].
- Author
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Chotkowska E, Jasiński B, and Rywik S
- Subjects
- Adult, Catchment Area, Health, Coronary Disease diagnosis, Coronary Disease epidemiology, Female, Humans, Male, Middle Aged, Poland epidemiology, Cholesterol blood, Hypercholesterolemia diagnosis, Hypercholesterolemia epidemiology, Population Surveillance
- Abstract
The aim of the study was to evaluate the level of lipid risk factors in a random sample of Warsaw population aged 35-64 years, 764 men and 775 women, were screened within framework of the Pol-MONICA Warsaw Study. The lipids were determined by enzymatic methods in laboratory controlled by CDC Lipid Standardization Program in Atlanta. In the screened sample the observed levels of total cholesterol (5.76 +/- 1.01 and 5.68 +/- 1.03 mmol/l respectively in men and in women) and LDL cholesterol (3.67 +/- 0.90 and 3.56 +/- 0.94 mmol/l respectively) were rather high what can indicate on rather high coronary risk of Warsaw population. On the other hand the high mean level of HDL cholesterol (1.36 +/- 0.36 and 1.53 +/- 0.35 mmol/l respectively) and its subfractions HDL2 (0.24 in men and 0.39 mmol/l in women) as well as HDL3 (1.12 and 1.14 mmol/l respectively) observed in this sample can decrease this global risk. The compared mean level of cholesterol in lipoprotein fractions in the group of investigated persons with and without clinical manifestations of coronary heart disease confirm the observed in the other studies the higher mean levels of total cholesterol and LDL cholesterol in persons with coronary heart disease.
- Published
- 1999
50. [Efficacy and safety of treating hyperlipidemia type II with fluvastatin in patients with arterial hypertension].
- Author
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Rywik S, Kłosiewicz-Latoszek L, Broda G, and Szostak WB
- Subjects
- Cholesterol, Dietary, Cholesterol, HDL blood, Cholesterol, LDL blood, Diet, Fat-Restricted, Female, Fluvastatin, Humans, Hyperlipidemias blood, Hyperlipidemias complications, Hyperlipidemias diet therapy, Male, Middle Aged, Triglycerides blood, Anticholesteremic Agents therapeutic use, Fatty Acids, Monounsaturated therapeutic use, Hyperlipidemias drug therapy, Hypertension complications, Indoles therapeutic use
- Abstract
62 patients with hyperlipidemia II and hypertension were 8 weeks on low fat and low cholesterol diet (acc. to EAS recommendations). If LDL-Ch > or = 4.1 mmol/l the diet was continued and 12 weeks treatment by fluvastatin (Lescol, Sandoz Pharma Ltd) started with control every 4 weeks Preliminary dosage 20 mg once daily in the evening increased to 40 mg if LDL-Ch > 3.5 mmol/l. After 12 weeks the mean level of T.Chol decreased by 21%, LDL-Ch by 29%, LDL-Ch/HDL-Ch by 31% and T.Chol/HDL-Ch by 24%. HDL-Ch increased by 8% and TG decreased by 5% but not significantly. The first goal of treatment (LDL-Ch < 4.14 mmol/l) achieved 73% and second (LDL-Ch < or = 3.5 mmol/l)-43.3% patients. In 2 patients treatment was discontinued (in one due to severe alimentary symptoms and in second-due to infection of respiratory tract with increase of SGOT and SGPT) and in next 2 the dosage was decreased to 20 mg/day (due to transitory alimentary symptoms).
- Published
- 1997
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