146 results on '"Rydzik, Anna M."'
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2. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
3. Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases
4. Use of ferrous iron by metallo-β-lactamases
5. Synthesis of 2′-modified N6-methyladenosine phosphoramidites and their incorporation into siRNA
6. Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis
7. A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases
8. Synthesis of 2’-Modified N6-Methyladenosine Phosphoramidites and Their Incorporation into Sirna
9. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
10. 19F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9cc06466d
11. Access to 1′-Amino Carbocyclic Phosphoramidite to Enable Postsynthetic Functionalization of Oligonucleotides
12. 19F‐NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo‐β‐Lactamase
13. Monitoring protein-metal binding by 19F NMR – a case study with the New Delhi metallo-β-lactamase 1
14. Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1† †Electronic supplementary information (ESI) available: Procedures for protein expression and purification, 19F-labelling, crystallisation, data collection, and structure determination, table of crystallographic data, table of crystallographic parameters and refinement statistics, figures showing binding mode and distances, procedures for mass spectrometry measurements, differential scanning fluorimetry measurements, stopped-flow measurements and other kinetics measurements. See DOI: 10.1039/c4sc01752h Click here for additional data file
15. Epigenetic Modification 6‐Methyladenosine Can Impact the Potency and Specificity of siRNA.
16. Comparison of Verona integron-borne metallo-ß-lactamase (VIM) variants reveals differences in stability and inhibition profiles
17. Comparison of verona integron-borne metallo-beta-lactamase (VIM) variants reveals differences in stability and inhibition profiles
18. mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation
19. 19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase
20. 19F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode.
21. Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase
22. Interaction of Avibactam with Class B Metallo-β-Lactamases
23. Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates
24. Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles
25. Frontispiece: Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis
26. Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis
27. Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
28. Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies
29. mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation.
30. 19F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.
31. Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1
32. Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition
33. Oxygenase‐Catalyzed Desymmetrization of N,N‐Dialkyl‐piperidine‐4‐carboxylic Acids
34. Oxygenase-Catalyzed Desymmetrization ofN,N-Dialkyl-piperidine-4-carboxylic Acids
35. ChemInform Abstract: Fluoromethylated Derivatives of Carnitine biosynthesis Intermediates — Synthesis and Applications.
36. Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases
37. Cover Picture: Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy (Angew. Chem. Int. Ed. 12/2014)
38. Titelbild: Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy (Angew. Chem. 12/2014)
39. 5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
40. Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by19F NMR Spectroscopy
41. Fluoromethylated derivatives of carnitine biosynthesis intermediates – synthesis and applications
42. Comparison of the substrate selectivity and biochemical properties of human and bacterial γ-butyrobetaine hydroxylase
43. Modulating carnitine levels by targeting its biosynthesis – selective inhibition of γ-butyrobetaine hydroxylase
44. Assay Platform for Clinically Relevant Metallo-β-lactamases
45. 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
46. Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases
47. Development and Application of a Fluoride-Detection-Based Fluorescence Assay for γ-Butyrobetaine Hydroxylase
48. Structure-Guided Design of Cell Wall Biosynthesis Inhibitors That Overcome β-Lactam Resistance in Staphylococcus aureus (MRSA)
49. Plant nucleoside 5'-phosphoramidate hydrolase; simple purification from yellow lupin (Lupinus luteus) seeds and properties of homogeneous enzyme.
50. Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis.
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