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6. The influence of renin angiotensin aldosterone system blockers on asymmetric dimethylarginine levels in patients with chronic glomerulonephritis

Author

Heleniak Zbigniew, Zdrojewski Zbigniew, Wisniewski Piotr, Bieniaszewski Leszek, Rutkowski Boleslaw, and Debska-Slizien Alicja

Subjects
asymmetric dimethylarginine, proteinuria, renin angiotensin aldosterone system, Medicine
Abstract

Endothelial dysfunction could be related to the limited availability of nitric oxide (NO). NO is synthesized with the participation of an NO synthase whose activity is inhibited by asymmetric dimethylarginine (ADMA). The synthesis of ADMA is exacerbated by oxidative stress, and several studies have shown the efficacy of drugs acting on the renin-angiotensin-aldosterone system (RAAS) (converting enzyme inhibitors and angiotensin II receptor antagonists) in reducing the level of ADMA. The probable mechanism of drug action is a reduction of oxidative stress through a decrease of angiotensin II formation. The aim of this study was to assess the influence of RAAS blockers on the plasma concentration of ADMA in patients with chronic glomerulonephritis (ChGN). The study included 37 patients, placed into group A and group B, depending on the treatment. Both groups were treated with RAAS blockers. In group B, immunosuppressive drugs were additionally administered. The control visits were at the 0, 6 and 12 months of observation. In both the studied groups (A+B), a significant reduction of ADMA (0.77 vs 0.4 μmol/l; p

Published
2016
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9. Low-Sodium Versus Standard-Sodium Peritoneal Dialysis Solution in Hypertensive Patients: A Randomized Controlled Trial

Author

Schwenger, V., Vychytil, A., Kopriva, G., van der Sande, F.M., Konings, C.J.A.M., Rensma, P.L., van Buren, M., Vleming, L.J., Książek, A., Klinger, M., Rutkowski, B., Myśliwiec, M., Nowicki, M., Sułowicz, W., Grzeszczak, W., Tam, P., Ouimet, D., Rutkowski, Bolesław, Tam, Paul, van der Sande, Frank M., Vychytil, Andreas, Schwenger, Vedat, Himmele, Rainer, and Gauly, Adelheid

Published
2016
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13. Aliskiren attenuates oxidative stress and improves tubular status in non-diabetic patients with chronic kidney disease-Placebo controlled, randomized, cross-over study

Author

Renke, Marcin, Lizakowski, Sławomir, Tylicki, Leszek, Rutkowski, Przemysław, Knap, Narcyz, Heleniak, Zbigniew, Sławińska-Morawska, Maja, Aleksandrowicz-Wrona, Ewa, Januszczyk, Jacek, Wójcik-Stasiak, Małgorzata, Małgorzewicz, Sylwia, Woźniak, Michał, and Rutkowski, Bolesław

Published
2014
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17. Safety of intravenous ferric carboxymaltose versus oral iron in patients with nondialysis-dependent CKD: an analysis of the 1-year FIND-CKD trial

Author

Roger, Simon D., Gaillard, Carlo A., Bock, Andreas H., Carrera, Fernando, Eckardt, Kai-Uwe, Van Wyck, David B., Cronin, Maureen, Meier, Yvonne, Larroque, Sylvain, Macdougall, Iain C., Gilles, Alastair, Faull, Randall, Toussaint, Nigel D., McMahon, Lawrence, Suranyi, Michael, Mudge, David, Hutchison, Brian, Irish, Ashley, Kerr, Peter, Kulkarni, Hemant, Elder, Grahame, Jardine, Margaret, Lhotta, Karl, Mayer, Gert, Vanholder, Raymond, Maes, Bart Dirk, Evenepoel, Pieter, Debelle, Frédéric, Jadoul, Michel, Dratwa, Max, Macel, Igor, Dunaj, Milan, Kvapil, Milan, Bucek, Petr, Rehorova, Jitka, Hruby, Ales, Honová, Václava, Malanova, Lada, Lucak, Martin, Lecian, Dalibor, Jirovec, Martin, Vlasak, Jiri, Rychlik, Ivan, Surel, Stanislav, Kamper, Anne-Lise, Ostergaard, Ove, Steffensen, Gudrun K, Chenine, Leila, Choukroun, Gabrial, Zaoui, Philippe, Wanner, Christoph, Backs, Wolfgang, Kraatz, Uwe, Dellanna, Frank, Busch, Klaus, Marsen, Tobias, Seeger, Wolfgang, Woitas, Rainer, Obermueller, Nicholas, Haak, Thomas, Lueders, Stephan, Pistrosch, Frank, Mueller, Eckhard, Mertens, Peter R., Sutermer, Werner, Grebe, Scott-Oliver, Hafezi-Rachti, Syrus, Roeser, Silke, Tsakiris, Dimitrios, Memmos, Dimitrios, Vlachakos, Demetrios, Vargemezis, Vassilis, Stefanidis, Ioannis, Syrganis, Christos, Alivanis, Polichronis, Papadakis, Ioannis, Papagalanis, Nickolaos, Andrikos, Aimilios, Goumenos, Dimitrios, Siamopoulos, Kostas, Gouva, Charikelia, Papadakis, Gabriel, Boletis, Ioannis, Tsimnadi-Spanoudaki, Myrsini, Stamatiades, Dimitrios, Stamatelou, Kyriaki, Moutafis, Spyridon, Locatelli, Francesco, Santoro, Antonio, Quarello, Francesco, Remuzzi, Giuseppe, Coppola, Salvatore, Mortellaro, Rosella Ferraro, Icardi, Andrea, Colussi, Giacomo, Grotta, Franco Della, Lombardi, Luigi, Gallieni, Maurizio, Villa, Giuseppe, Grandaliano, Giuseppe, Gaillard, Carlo, Huisman, Sebastiaan, Barendregt, Jos, Smak Gregoor, Peter JH, Oien, Cecilia, Rutkowski, Boleslaw, Malecki, Robert, Nowicki, Michal, Rutkowski, Przemyslaw, Marczewski, Kryzsztof, Mysliwiec, Michal, Sydor, Antoni, Rysz, Jacek, Rydzewski, Andrzej, Klinger, Marian, Wnuk, Rafal, Kozminski, Piotr, Nocon, Anna, Ciechanowski, Kazimierz, Correia, Pedro, Neves, Fernando, Barata, José, Mircescu, Gabriel, Voiculescu, Mihai, Gluhovschi, Gheorghe, Mota, Eugen, De Francisco, Angel Luís Martín, Torre, Alberto, Herreros, Alba, Luño, José, Gruss, E., Martins, Judith, Vallés, Marti, Pascual, Julio, Bárány, Peter, Ambuehl, Patrice M., Erturk, Sehsuvar, Arici, Mustafa, Paydas, Saime, Soypacaci, Zeki, Camsari, Taner, Ustundag, Sedat, Thomas, Mark E., DʼSouza, Richard J., Taylor, Jo E., Pritchard, Nicholas R., Jeffery, Robin, Riley, Stephen G., Bhatnagar, Deepak, Bhandari, Sunil, Reaich, David, Stevens, Paul E., El Kossi, Mohsen, Roe, Simon, Camilleri, Brian, Ahmed, Aimun, Khwaja, Arif, Thompson, Barbara, Banerjee, Debasish, Nicholas, Johann, Hutchison, Alastair, and Borrows, Richard

Published
2017
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25. Improvement of mineral and bone metabolism markers is associated with better survival in haemodialysis patients: the COSMOS study

Author

Fernández-Martín, José Luis, Martínez-Camblor, Pablo, Dionisi, María Paula, Floege, Jürgen, Ketteler, Markus, London, Gérard, Locatelli, Francesco, Gorriz, José Luis, Rutkowski, Boleslaw, Ferreira, Aníbal, Bos, Willem-Jan, Covic, Adrian, Rodríguez-García, Minerva, Sánchez, José Emilio, Rodríguez-Puyol, Diego, Cannata-Andia, Jorge B., Benedik, Miha, Carrero, Juan Jesus, Goldsmith, David, Kramar, Reinhard, Martin, Pierre-Yves, Memmos, Dimitrios, Nagy, Judit, Pavlovic, Drasko, Teplan, Vladimir, Tielemans, Christian, Verbeelen, Dierik, and Wüthrich, Rudolf P.

Published
2015
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27. Renal replacement therapy in Europe-a summary of the 2010 ERA-EDTA Registry Annual Report

Author

Kramer, Anneke, Stel, Vianda S., Abad Diez, José Maria, Alonso de la Torre, Ramón, Bouzas Caamaño, Encarnación, Čala, Svjetlana, Cao Baduell, Higini, Castro de la Nuez, Pablo, Cernevskis, Harijs, Collart, Frederic, Couchoud, Cécile, de Meester, Johan, Djukanovic, Ljubica, Ferrer-Alamar, Manuel, Finne, Patrik, Fogarty, Damian, de los Ángeles García Bazaga, María, Garneata, Liliana, Golan, Eliezer, González Fernández, Raquel, Heaf, James G., Hoitsma, Andries, Ioannidis, George A., Kolesnyk, Mykola, Kramar, Reinhard, Leivestad, Torbjørn, Limido, Aurelio, Lopot, Frantisek, Macario, Fernando, Magaz, Ángela, Martín-Escobar, Eduardo, Metcalfe, Wendy, Noordzij, Marlies, Ots-Rosenberg, Mai, Palsson, Runolfur, Piñera, Celestino, Postorino, Maurizio, Prutz, Karl G., Ratkovic, Marina, Resic, Halima, Rodríguez Hernández, Aurelio, Rutkowski, Boleslaw, Serdengeçti, Kamil, Yebenes, Tomas Sierra, Spustová, Viera, Stojceva-Taneva, Olivera, Tomilina, Natalia A., van de Luijtgaarden, Moniek W.M., van Stralen, Karlijn J., Wanner, Christoph, Jager, Kitty J., Universitat Autònoma de Barcelona, Amsterdam Cardiovascular Sciences, Amsterdam Public Health, and Medical Informatics

Subjects
medicine.medical_specialty, Ronyons -- Malalties -- Pacients -- Europa -- Estadístiques, medicine.medical_treatment, Population, 030232 urology & nephrology, 030204 cardiovascular system & hematology, urologic and male genital diseases, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Renal replacement therapy, education, Dialysis, Transplantation, education.field_of_study, business.industry, Incidence (epidemiology), Medical record, Special Feature, Confidence interval, 3. Good health, Educational Papers, Nephrology, Hemodialysis, business
Abstract

BACKGROUND: This study provides a summary of the 2010 European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report (available at www.era-edta-reg.org). METHODS: This report includes data on renal replacement therapy (RRT) using data from the national and regional renal registries in 29 countries in Europe and bordering the Mediterranean Sea. Individual patient data were received from 27 registries, whereas 18 registries contributed data in aggregated form. We present incidence and prevalence of RRT, transplant rates, survival probabilities and expected remaining lifetimes. The latter two are solely based on individual patient records. RESULTS: In 2010, the overall incidence rate of RRT for end-stage renal disease (ESRD) among all registries reporting to the ERA-EDTA Registry was 123 per million population (pmp) (n = 91 798). The highest incidence rate was reported by Turkey (252pmp) and the lowest reported by Montenegro (21 pmp). The overall prevalence of RRT for ESRD at 31 December 2010 among all registries reporting to the ERA-EDTA Registry was 741 pmp (n = 551 005). The prevalence varied from 124 pmp in Ukraine to 1580 pmp in Portugal. The overall number of renal transplantations performed in 2010 among all registries was 29.2 pmp (n = 21 740). The highest overall transplant rate was reported from Spain, Cantabria (73 pmp), whereas the highest transplant rate for living donor kidneys was reported from the Netherlands (28 pmp). For patients who started RRT between 2001 and 2005, the unadjusted 5-year patient survival on RRT was 46.2% [95% confidence interval (CI) 46.0-46.3], and on dialysis 38.6% (95% CI 38.5-38.8). The unadjusted 5-year patient survival after the first renal transplantation performed between 2001 and 2005 was 86.6% (95% CI 86.1-87.1) for deceased donor kidneys and 94.1% (95% CI 93.4-94.8) for living donor kidneys.

Published
2021

28. Survival with low- and high-flux dialysis

Author

Sánchez-Álvarez, Emilio, Rodríguez-García, Minerva, Ferreira, Anibal, Pavlovic, Drasko, Cannata-Andía, Jorge B., Fernández-Martín, José L., COSMOS Group, Motellón, José Luis, Turner, Matthew, Chaussy, Julien, Molemans, Bart, Zani, Wal, Locatelli, Francesco, Rosser, Dylan, Dehmel, Bastian, Fouqueray, Bruno, Bradbury, Brian, Acquavella, John, Hollowell, Jennifer, Carter, Dave, Holland, Phil, Baños, Ana, Mattin, Caroline, Zoccali, Carmine, Critchlow, Cathy, Kim, Joseph, Lewis, Charlotte, Panayi, Antonia, Hemetsberger, Margit, Croft, Stephen, Jaeger, Philippe, Muehlebach, Prisca, Blackburn, Jane, Zumsteg, Esther, Martín-Malo, Alejandro, Gurevich, Andrey, Rodríguez, Silvia, Pérez, Angel, Faner, Pau, Izco, Irantzu, Traseira, Susana, Castro, Carmen, Moreno, Javier, Calle, David, Pieraccini, Francesca, Flöge, Jürgen, Ketteler, Markus, London, Gerard, Górriz, José L., and Rutkowski, Boleslaw

Subjects
medicine.medical_specialty, medicine.medical_treatment, Population, 030232 urology & nephrology, 030204 cardiovascular system & hematology, Peritoneal dialysis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, ddc:610, AcademicSubjects/MED00340, education, Dialysis, Transplantation, education.field_of_study, chronic haemodialysis, business.industry, Mortality rate, Hazard ratio, Original Articles, mortality, Nephrology, Relative risk, Propensity score matching, dialysis, mortality risk, Hemodialysis, business, dialysis membranes
Abstract

The National Program of I + D + I 2008–2011 and Instituto de Salud Carlos III (ISCIII), the ISCIII Retic REDinREN (RD06/0016/1013, RD12/0021/0023 and RD16/ 0009/0017), the ISCIII (ICI14/00107, PI17/00384 and PI20/00633), Fondo Europeo de Desarrollo Regional (FEDER), Plan Estatal de I + D + I 2013–2016, Plan de Ciencia, Tecnología e Innovación 2013–2017 y 2018–2022 del Principado de Asturias (GRUPIN14-028, IDI-2018-000152) (...), Sanchez-Alvarez, E; Rodriguez-Garcia, M; Locatelli, F; Zoccali, C; Martin-Malo, A; Floege, J; Ketteler, M; London, G; Gorriz, JL; Rutkowski, B; Ferreira, A; Pavlovic, D; Cannata-Andia, JB; Fernandez-Martin, JL

Published
2021

34. CKD MBD

Author

Dionisi, María P, Fernández-Martín, José L, Martínez-Camblor, Pablo, Floege, Jürgen Floege, Ketteler, Markus, London, Gérard, Locatelli, Francesco, Gorriz, José L., Rutkowski, Boleslaw, Ferreira, Aníbal, Covic, Adrian, and Cannata-Andía, Jorge B

Published
2014

43. COSMOS: the dialysis scenario of CKD–MBD in Europe

Author

Fernández-Martín, José Luis, Carrero, Juan Jesus, Benedik, Miha, Bos, Willem-Jan, Covic, Adrian, Ferreira, Aníbal, Floege, Jürgen, Goldsmith, David, Gorriz, José Luis, Ketteler, Markus, Kramar, Reinhard, Locatelli, Francesco, London, Gérard, Martin, Pierre-Yves, Memmos, Dimitrios, Nagy, Judit, Naves-Díaz, Manuel, Pavlovic, Drasko, Rodríguez-García, Minerva, Rutkowski, Boleslaw, Teplan, Vladimir, Tielemans, Christian, Verbeelen, Dierik, Wüthrich, Rudolf P., Martínez-Camblor, Pablo, Cabezas-Rodriguez, Iván, Sánchez-Alvarez, José Emilio, and Cannata-Andia, Jorge B.

Published
2013
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