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2. Preserving stroke care during the COVID-19 pandemic: Potential issues and solutions

Author

Leira, Enrique C., Russman, Andrew N., Biller, José, Brown, Devin L., Bushnell, Cheryl D., Caso, Valeria, Chamorro, Angel, Creutzfeldt, Claire J., Cruz-Flores, Salvador, Elkind, Mitchell S.V., Fayad, Pierre, Froehler, Michael T., Goldstein, Larry B., Gonzales, Nicole R., Kaskie, Brian, Khatri, Pooja, Livesay, Sarah, Liebeskind, David S., Majersik, Jennifer J., Moheet, Asma M., Romano, Jose G., Sanossian, Nerses, Sansing, Lauren H., Silver, Brian, Simpkins, Alexis N., Smith, Wade, Tirschwell, David L., Wang, David Z., Yavagal, Dileep R., and Worrall, Bradford B.

Published
2020
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7. Contributors

Author

Aminoff, Michael J., Pomeroy, Scott L., Levin, Kerry H., Abbatemarco︎, Justin R., Abdulrazzak︎, Mohammad Ammar, Aboseif︎, Albert, Adams, Harold P., Jr, Alrohimi, Anas, Amin︎, Moein, Barkoudah︎, Elizabeth, Bermel︎, Robert A., Bethoux︎, Francois, Brennan︎, Brian P., Buletko︎, Andrew Blake, Chandra︎, Rahul, Chaves︎, Claudia, Cohen︎, Jeffrey A., Cole-Lewis︎, Yasmin, Connery︎, Hilary S., Conway︎, Devon S., Cusin, Cristina, Cutsforth-Gregory︎, Jeremy K., Eaton︎, James E., Fernandes︎, Serena, Fox︎, Robert, Freudenreich︎, Oliver, Fullerton︎, Heather J., Gálvez-Jiménez︎, Néstor, Gomes︎, Joao, Chaves︎, Adriana Graciela Grau, Hida︎, Rahma, Holmes︎, Gregory L., Hussain, Shazam, Isaken, Imari-Ashley P., Kase, Carlos S., Kaufman︎, Milissa L., Kharal︎, G. Abbas, Khawaja︎, Zeshaun, Kieran︎, Kathryn, Kunchok︎, Amy, Ibrikji︎, Sidonie, LaManti︎a, Anthony-Samuel, Linder︎, Susan M., Lipton︎, Jonathan, Lu︎, Mei, Lu-Emerson︎, Christine, Mack︎, Kenneth J., Mahadeen︎, Ahmad, Mahajan, Kedar R., Mahapatra, Ashutosh, McGinley︎, Marisa, Medina-DeVilliers︎, Sara, Morgan︎, Annalisa, Moss︎, Brandon, Nonacs, Ruta M., O’Connor︎, Ryan, Ontaneda︎, Daniel, Oster︎, Joel M., Paden︎, Sherry, Pandhi, Abhi, Percy︎, Alan K., Pleen, Joseph, Reese︎, Joelle, Rensel︎, Mary R., Robertson︎, Carrie (Beth) E., Robinson︎, Shenandoah, Roeder︎, Hannah J., Roos︎, Karen L., Russman︎, Andrew N., Samsel︎, Chase, Saper︎, Clifford B., Schmahmann︎, Jeremy D., Scott︎, Rodney C., Selim︎, Magdy, Shin︎, Ah Lahm, Shinn︎, Ann K., Sorrentino︎, Renee, Swerdlow︎, Russell H., Tasker︎, Robert C., Taylor︎, Samantha Marie, Toth, Gabor, Tritos︎, Nicholas A., Tsang︎, Kevin K., Voetsch︎, Barbara, Wen︎, Patrick Y., Whealy︎, Mark A., Wilberger︎, Jack, Winkelman︎, John W., and Wulff︎, Charles R.

Published
2025
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20. Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid)

Author

Griffiths, Christopher E.M., Russman, Andrew N., Majmudar, Gopa, Singer, Robert S., Hamilton, Ted A., and Voorhees, John J.

Subjects
Collagen, Tretinoin -- Health aspects, Skin -- Physiological aspects
Abstract

A correlation may exist between topical application of tretinoin and an increase in collagen I production in sun-damaged skin. The formation of collagen, a protein that is a component of connective tissue, is decreased in sun-damaged human skin. Skin biopsies were performed on 26 healthy, white participants. Analysis of biopsies from sun-protected areas of the buttocks and sun-damaged areas of the participants' forearms indicated that collagen I formation was significantly lessened in the damaged skin. An additional 29 white patients were randomly assigned to apply either a topical preparation of 0.1% tretinoin cream or a similar-looking placebo cream with no active ingredients. Some of the patients were treated for 10 months and some for 12 months. Biopsies were performed before treatment began and again at the end of treatment. Analysis of the biopsies found a 119% increase in collagen I staining of fibroblasts and an 80% increase in extracellular collagen I formation in patients treated with tretinoin. There was an 18% decrease in collagen staining of fibroblasts in patients who received the placebo.

Published
1993

28. Reduction in time to treatment in prehospital telemedicine evaluation and thrombolysis

Author

Taqui, Ather, primary, Cerejo, Russell, additional, Itrat, Ahmed, additional, Briggs, Farren B.S., additional, Reimer, Andrew P., additional, Winners, Stacey, additional, Organek, Natalie, additional, Buletko, Andrew B., additional, Sheikhi, Lila, additional, Cho, Sung-Min, additional, Buttrick, Maureen, additional, Donohue, Megan M., additional, Khawaja, Zeshaun, additional, Wisco, Dolora, additional, Frontera, Jennifer A., additional, Russman, Andrew N., additional, Hustey, Fredric M., additional, Kralovic, Damon M., additional, Rasmussen, Peter, additional, Uchino, Ken, additional, and Hussain, Muhammad S., additional

Published
2017
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31. Intra-Arterial Thrombolysis in Acute Ischemic Stroke.

Author

Tarsy, Daniel, Lyden, Patrick D., Furlan, Anthony J., Higashida, Randall, Katzan, Irene, Abou-Chebl, Alex, and Russman, Andrew N.

Abstract

Intra-arterial (IA) thrombolysis provides an alternative to intravenous (iv) thrombolysis in selected patients with acute ischemic stroke. Recent advances in the field of neuro-interventional radiology, with the development of extremely soft, compliant microcatheters and steerable microguidewires, along with high-resolution fluoroscopy and digital imaging, and nonionic contrast agents, have made it feasible and safe to access the major intracranial blood vessels around the circle of Willis from a percutaneous transfemoral approach under local anesthesia. Rapid local delivery of fibrinolytic agents is now feasible using these techniques and is performed at many major medical centers in selected patients with acute cerebral ischemia. [ABSTRACT FROM AUTHOR]

Published
2005
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33. Creating accountable care for carotid angioplasty and stenting: A multidisciplinary carotid revascularization board.

Author

Kole, Maximilian K., Khan, Muhib, Marin, Horia, Sanders, William, Shepard, Alexander, Katramados, Angelos M., Russman, Andrew N., Gellman, Steven, Nypaver, Timothy, Malik, Ghaus, and Mitsias, Panayiotis D.

Subjects
REVASCULARIZATION (Surgery), CAROTID artery, ANGIOPLASTY, SURGICAL stents, VASCULAR surgery, NEUROSURGEONS
Abstract

Background: We tested the feasibility of a mandated multidisciplinary carotid revascularization board (MDCB) to review, approve and monitor all carotid artery and stenting (CAS) procedures and outcomes at our institution. Methods: The board was composed of vascular surgeons, cardiologists, interventional neuroradiologists, neurosurgeons, and neurologists, who met weekly to facilitate an evidence-based, consensus recommendation to ensure appropriate CAS referral. Results: The board successfully reviewed and continues to review and approve all CAS procedures at our center. Of the 69 patients considered high risk for standard surgical treatment, 42 patients were symptomatic and 27 patients were asymptomatic. Their mean age was 70.5-year-old and the median degree of stenosis was 79%. In the 74 procedures, periprocedural complications occurred at the following rates: 2.7% death, 2.7% major stroke, 2.7% minor stroke, and 2.7% myocardial infarction (MI) within 30 days of the procedure. At 1 year the primary endpoints of ipsilateral stroke and neurovascular-related death were observed in 8.1% and 2.7% of the patients, respectively. At mean follow-up of 21 months, 18.8% of the patients (13/69) had died (including all causes), and 14.5% (10/69) experienced stroke (including nontarget strokes). Target vessel revascularization was needed in 2.9% patients. Conclusions: A mandated multidisciplinary carotid revascularization board MDCB is feasible and potentially advantageous in real clinical practice. It establishes a model for accountable care by providing a mechanism for institutional oversight, credentialing operators, quality review, standardizing care, cost containment and eliminating the "subspecialty silo mentality." [ABSTRACT FROM AUTHOR]

Published
2012
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