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1,566 results on '"Rush, A. J."'

10. Defining mitochondrial protein functions through deep multiomic profiling

Author

Rensvold, Jarred W., Shishkova, Evgenia, Sverchkov, Yuriy, Miller, Ian J., Cetinkaya, Arda, Pyle, Angela, Manicki, Mateusz, Brademan, Dain R., Alanay, Yasemin, Raiman, Julian, Jochem, Adam, Hutchins, Paul D., Peters, Sean R., Linke, Vanessa, Overmyer, Katherine A., Salome, Austin Z., Hebert, Alexander S., Vincent, Catherine E., Kwiecien, Nicholas W., Rush, Matthew J. P., Westphall, Michael S., Craven, Mark, Akarsu, Nurten A., Taylor, Robert W., Coon, Joshua J., and Pagliarini, David J.

Published
2022
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12. Creating a Palliative Care Clinic for Patients with Cancer Pain and Substance Use Disorder

Author

Kale, Sachin S., primary, Tosto, Gennaro Di, additional, Rush, Laura J., additional, Kullgren, Justin, additional, Russell, Deborah, additional, Fried, Martin, additional, Igboeli, Blessing, additional, Teater, Julie, additional, Jones, Katie Fitzgerald, additional, Check, Devon K., additional, Merlin, Jessica, additional, and McAlearney, Ann Scheck, additional

Published
2024
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15. Thermodynamic Formalism for Iterated Function Systems

Author

Rush, Tom J and Rush, Tom J

Abstract

The purpose of this thesis to present two works in the field of thermodynamic formalism. The first concerns multifractal decompositions based on Birkhoff averages for expanding interval maps with countably many branches which we assume can be coded by topologically mixing countable Markov shifts. This generalises previous work on expanding maps with finitely many branches, and expanding maps with countably many branches where the coding is assumed to be the full shift. In the second, we prove the existence of Gibbs-type measures for some superadditive sequences of matrix-norm potentials defined on subshifts of finite type. This extends the results of the well-understood subadditive setting.

Published
2024

16. When Infections Are Found: A Qualitative Study Characterizing Best Management Practices for Central Line-Associated Bloodstream Infection and Catheter-Associated Urinary Tract Infection Performance Monitoring and Feedback.

Author

Gaughan, Alice A., MacEwan, Sarah R., Gregory, Megan E., Eramo, Jennifer L., Rush, Laura J., Hebert, Courtney L., and McAlearney, Ann Scheck

Subjects
PREVENTION of bloodborne infections, MEDICAL protocols, CORPORATE culture, RESEARCH funding, QUALITATIVE research, INTERPROFESSIONAL relations, ACADEMIC medical centers, PATIENT safety, CATHETER-related infections, LEADERSHIP, INTERVIEWING, MEDICAL coding software, RESPONSIBILITY, JUDGMENT sampling, HOSPITAL emergency services, THEMATIC analysis, ATTITUDES of medical personnel, RESEARCH methodology, CATHETER-associated urinary tract infections, PATIENT monitoring, QUALITY assurance, HEALTH care teams
Abstract

Healthcare-associated infections (HAIs) remain a significant patient safety problem that can lead to illness and death, despite the implementation of clinical bundles to prevent HAIs. Management practices can support HAI prevention, but their role in HAI performance monitoring and feedback is not well understood. To address this knowledge gap, we previously conducted semi-structured interviews with staff at 18 hospitals to examine the role of management practices around the prevention of central line-associated bloodstream infections (CLABSIs) and catheter-associated urinary tract infections (CAUTIs). Interview transcripts were analyzed to identify themes related to HAI performance monitoring and feedback. The current analysis focuses on 10 higher-performing hospitals that were successful in preventing CLABSIs and CAUTIs. These institutions had robust practices including timely event analysis, leadership engagement, and multidisciplinary participation in HAI reviews. Across these sites, we found common goals including investigating HAIs without blame and identifying opportunities for improvement. Management practices such as timely analysis of HAIs, collaboration between facility leadership and multidisciplinary team members, and a focus on identifying the failure of a procedure or protocol, rather than the failure of staff members, are all approaches that can support infection prevention efforts. These management practices may be especially important as hospitals attempt to address increases in CLABSI and CAUTI rates that may have occurred during the coronavirus pandemic. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Which factors influence the approach to shared decision-making among surgeons performing complex operations?

Author

Palmer Kelly, Elizabeth, Rush, Laura J., Melnyk, Halia L., Eramo, Jennifer L., McAlearney, Ann Scheck, and Pawlik, Timothy M.

Subjects
*CROSS-sectional method, *PEARSON correlation (Statistics), *ACADEMIC medical centers, *DATA analysis, *QUESTIONNAIRES, *VISUAL analog scale, *SURGEONS, *DECISION making, *DESCRIPTIVE statistics, *CHI-squared test, *OPERATIVE surgery, *SURVEYS, *PHYSICIAN-patient relations, *RESEARCH methodology, *PSYCHOMETRICS, *ONE-way analysis of variance, *STATISTICS, *SOCIAL skills, *DATA analysis software, *PSYCHOSOCIAL factors, *DEMOGRAPHY, *PATIENTS' attitudes, *PATIENT participation
Abstract

Shared decision-making (SDM) aims to create a context in which patients and surgeons work together to explore treatment options and goals of care. The objective of the current study was to characterize demographic factors, behaviors, and perceptions of patient involvement among surgeons relative to SDM. Using a cross-sectional survey methodology, surgeon demographics, behaviors, and perceptions of patient involvement were assessed. Surgeon approaches to SDM were measured using a 100-point scale ranging from 'patient-led' (0) to 'surgeon-led' (100). Among 241 respondents, most were male (n = 123, 67.2%) and White (n = 124, 69.3%); roughly one-half of surgeons had been in practice ≥10 years (n = 120, 52.4%). Surgeon approaches to SDM ranged from 0 to 81.0, with a median rating of 50.0 (IQR: 35.5, 62.0). Reported approaches to SDM were associated with years in practice, sharing information, and perceptions of patient involvement. Surgeons in practice 10 + years most frequently utilized a 'Shared, Patient-led' approach to SDM (27.5%), while individuals with less experience more often employed a 'Shared, Surgeon-led' approach (33.3%, p = 0.031). Surgeons with a 'Patient-led' approach perceived patient involvement as most important (M = 3.82, SD = 0.16), while respondents who had a 'Surgeon-led' approach considered this less important (M = 3.57, SD = 0.38; p < 0.001). Surgeon factors including demographics, behaviors, and perceptions of patient involvement influenced SDM approaches. SDM between patients and surgeons should strive to be more dynamic and tailored to each specific patient's needs to promote optimal patient-centered care. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Utilization of Palliative and Hospice Care Among Pancreatic Cancer Patients at an Academic Center

Author

Chawla, Mehak, primary, Villarreal, Michael E., additional, Waterman, Brittany L., additional, Di Tosto, Gennaro, additional, Gonzalez, Roberto, additional, Sarna, Angela, additional, Patel, Romal, additional, Cloyd, Jordan, additional, Pawlik, Timothy M., additional, Rush, Laura J., additional, McAlearney, Ann, additional, and Ejaz, Aslam, additional

Published
2023
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31. Spin fluctuations in a magnetically frustrated metal, LiV2O4

Author

Lee, S. -H., Qiu, Y., Broholm, C., Ueda, Y., and Rush, J. J.

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

Inelastic neutron scattering is used to characterize spin fluctuations in the $d$-electron heavy fermion spinel $\rm LiV_2O_4$. The spin relaxation rate, $\Gamma_Q$, for $Q=0.6$ \AA$^{-1}$ is 1.5(1) meV at low temperatures and increases linearly with temperature at a rate of 0.41(4) k$_B$. There is antiferromagnetic short range order at low temperatures with a characteristic wave vector $Q_c= 0.64(2)$ \AA$^{-1}$ and a correlation length of 6(1) \AA . Warming shifts intensity towards lower $Q$ so that magnetic scattering decreases monotonically with $Q>0.3$ \AA$^{-1}$ for $T>40$ K. The data are compared with conventional heavy fermion systems, geometrically frustrated insulating magnets, and recent theories for $\rm LiV_2O_4$., Comment: 4 pages, 3 figs included, accepted for publication in Phys. Rev. Lett

Published
2001
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33. Restriction landmark genomic scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations.

Author

Smiraglia, Dominic J, Kazhiyur-Mannar, Ramakrishnan, Oakes, Christopher C, Wu, Yue-Zhong, Liang, Ping, Ansari, Tahmina, Su, Jian, Rush, Laura J, Smith, Laura T, Yu, Li, Liu, Chunhui, Dai, Zunyan, Chen, Shih-Shih, Wang, Shu-Huei, Costello, Joseph, Ioshikhes, Ilya, Dawson, David W, Hong, Jason S, Teitell, Michael A, Szafranek, Angela, Camoriano, Marta, Song, Fei, Elliott, Rosemary, Held, William, Trasler, Jacquetta M, Plass, Christoph, and Wenger, Rephael

Subjects
Intestinal Mucosa, Liver, Animals, Humans, Mice, DNA Restriction Enzymes, Electrophoresis, Gel, Two-Dimensional, Restriction Mapping, Computational Biology, Genomics, Organ Specificity, DNA Methylation, CpG Islands, Genome, Genome, Human, Electrophoresis, Gel, Two-Dimensional, Human, Intestines, Biological Sciences, Information and Computing Sciences, Medical and Health Sciences, Bioinformatics
Abstract

BackgroundRestriction landmark genomic scanning (RLGS) is one of the most successfully applied methods for the identification of aberrant CpG island hypermethylation in cancer, as well as the identification of tissue specific methylation of CpG islands. However, a limitation to the utility of this method has been the ability to assign specific genomic sequences to RLGS spots, a process commonly referred to as "RLGS spot cloning."ResultsWe report the development of a virtual RLGS method (vRLGS) that allows for RLGS spot identification in any sequenced genome and with any enzyme combination. We report significant improvements in predicting DNA fragment migration patterns by incorporating sequence information into the migration models, and demonstrate a median Euclidian distance between actual and predicted spot migration of 0.18 centimeters for the most complex human RLGS pattern. We report the confirmed identification of 795 human and 530 mouse RLGS spots for the most commonly used enzyme combinations. We also developed a method to filter the virtual spots to reduce the number of extra spots seen on a virtual profile for both the mouse and human genomes. We demonstrate use of this filter to simplify spot cloning and to assist in the identification of spots exhibiting tissue-specific methylation.ConclusionThe new vRLGS system reported here is highly robust for the identification of novel RLGS spots. The migration models developed are not specific to the genome being studied or the enzyme combination being used, making this tool broadly applicable. The identification of hundreds of mouse and human RLGS spot loci confirms the strong bias of RLGS studies to focus on CpG islands and provides a valuable resource to rapidly study their methylation.

Published
2007

37. Prevalence of Violence against Providers in Heart and Lung Transplant Programs

Author

Barrett, Todd A., primary, Di Tosto, Gennaro, additional, Shiu-Yee, Karen, additional, Melnyk, Halia L., additional, Rush, Laura J., additional, Sova, Lindsey N., additional, Lampert, Brent C., additional, Ganapathi, Asvin M., additional, Whitson, Bryan A., additional, Waterman, Brittany L., additional, and McAlearney, Ann Scheck, additional

Published
2023
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40. Characterization of Potential for Relationship between Anxiety and Cardiovascular Health in Different Racial Groups: 429 Board #267 May 29 11:00 AM - 12:30 PM

Author

Lee, Zana B., Blaszkow, Emily N., Dickinson, Rachel L., Baker, Clara N., Reeve, Emily H., Gill, Kevin M., OʼBrien, Matisen L., Magliochetti, Concetta M., Pak, Christopher S., Orfe, Amber N., Carty, Megan A., Rush, Lindsay J., Clarke, Brielle S., Ruch, Emily E., DeAlba, Paige E., Coleman, Rachel L., Getty, Allyson K., Derella, Cassandra C., Perez, Avery N., Oakman, Joyann E., Volpe, Vanessa V., Brown, Michael D., and Feairheller, Deborah L.

Published
2019
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42. The effects of a nutritional packet (live yeast, vitamins C and B1, and electrolytes) offered to steers in a calf-fed system on growth performance, nutrient digestion, feeding behavior, carcass characteristics, and ruminal variables

Author

Rush, Camron J, primary, Sarturi, Jhones O, additional, Huerta-Leidenz, Nelson O, additional, Woerner, Dale R, additional, Crossland, Whitney L, additional, Henry, Darren D, additional, Silva, Kaliu G S, additional, and Lopez, Alejandra M, additional

Published
2023
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48. 339 Growth Performance and Carcass Characteristics of Feedlot Beef Yearling Steers Offered Finishing Diets with Direct fed Microbial Mixtures

Author

Lopez, Alejandra M, primary, Sarturi, Jhones O, additional, Henry, Darren H, additional, Ciriaco, Francine M, additional, Johnson, Bradley J, additional, Woerner, Dale R, additional, Scaranto Silva, Kaliu G, additional, Nardi, Kaue Tonelli, additional, Rush, Camron J, additional, Rodrigues, Barbara, additional, Peters, Sarah, additional, Manna, Mikala Di, additional, Osorio-Doblado, Andrea M, additional, Coello, Kymberly, additional, and Quijada, Angel A, additional

Published
2022
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49. PSVIII-18 Nutrient Digestibility of Feedlot Beef Yearling Steers Offered Finishing Diets with Direct fed Microbial Mixtures

Author

Lopez, Alejandra M, primary, Sarturi, Jhones O, additional, Henry, Darren H, additional, Ciriaco, Francine M, additional, Johnson, Bradley J, additional, Scaranto Silva, Kaliu G, additional, Nardi, Kaue Tonelli, additional, Rush, Camron J, additional, Rodrigues, Barbara, additional, Peters, Sarah, additional, and Manna, Mikala Di, additional

Published
2022
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50. PSIX-5 Ruminal Papillae Morphology and Volatile Fatty Acid Profile of Beef Steers Consuming Finishing Diets with an Added Nutritional Packet in a Calf-fed System

Author

Peters, Sarah, primary, Sarturi, Jhones O, additional, Rush, Camron J, additional, Felizari, Luana, additional, Henry, Darren D, additional, Huerta-Leidenz, Nelson O, additional, Woerner, Dale R, additional, Rodrigues, Barbara, additional, Lopez, Alejandra M, additional, Silva, Kaliu G Scaranto, additional, Nardi, Kaue Tonelli, additional, and Wilkes, Katherine, additional

Published
2022
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