1. A new staging system using right atrial strain in patients with immunoglobulin light‐chain cardiac amyloidosis
- Author
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Hiroki Usuku, Eiichiro Yamamoto, Daisuke Sueta, Rumi Shinriki, Fumi Oike, Noriaki Tabata, Masanobu Ishii, Shinsuke Hanatani, Tadashi Hoshiyama, Hisanori Kanazawa, Yuichiro Arima, Seiji Takashio, Yawara Kawano, Seitaro Oda, Hiroaki Kawano, Mitsuharu Ueda, and Kenichi Tsujita
- Subjects
B‐type natriuretic peptide ,Immunoglobulin light‐chain cardiac amyloidosis ,Right atrial strain during the reservoir phase ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims There are minimal data on the prognostic impact of right atrial strain during the reservoir phase (RASr) in patients with immunoglobulin light‐chain (AL) cardiac amyloidosis. Methods and results Among 78 patients who were diagnosed with AL cardiac amyloidosis at Kumamoto University Hospital from 2007 to 2022, 72 patients with sufficient two‐dimensional speckle tracking imaging data without chemotherapy before the diagnosis were retrospectively analysed. During a median follow‐up of 403 days, 31 deaths occurred. Age and the rate of male sex were not significantly different between the all‐cause death group and the survival group (age, 70.4 ± 8.8 years vs. 67.0 ± 10.0 years, P = 0.14, male sex, 65% vs. 66%, P = 0.91). The estimated glomerular filtration rate (eGFR) was significantly lower, and B‐type natriuretic peptide (BNP) and high sensitivity cardiac troponin T (hs‐cTnT) were significantly higher, in the all‐cause death group versus the survival group (eGFR, 48.2 ± 21.0 mL/min/1.73 m2 vs. 59.4 ± 24.4 mL/min/1.73 m2, P 311.2 pg/mL) had a significantly high probability of all‐cause death (both, P
- Published
- 2024
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