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22 results on '"Rumetshofer, Rudolf"'

3. Multidrug-resistant tuberculosis in Europe, 2010-2011

Author

Gunther, Gunar, van Leth, Frank, Alexandru, Sofia, Altet, Neus, Avsar, Korkut, Bang, Didi, Barbuta, Raisa, Bothamley, Graham, Ciobanu, Ana, Crudu, Valeriu, Danilovits, Manfred, Dedicoat, Martin, Duarte, Raquel, Gualano, Gina, Kunst, Heinke, de Lange, Wiel, Leimane, Vaira, Magis-Escurra, Cecile, McLaughlin, Anne-Marie, Muylle, Inge, Polcova, Veronika, Pontali, Emanuele, Popa, Christina, Rumetshofer, Rudolf, Skrahina, Alena, Solodovnikova, Varvara, Spinu, Victor, Tiberi, Simon, Viiklepp, Piret, and Lange, Christoph

Subjects
Drug resistance in microorganisms, Pyrazinamide -- Evaluation, Tuberculosis, Health, European Union, World Health Organization
Abstract

Emergence of drug-resistant tuberculosis (TB) threatens the goal of TB elimination (1). Multidrug-resistant (MDR) TB is defined by in vitro resistance of Mycobacterium tuberculosis to at least both of the [...]

Published
2015
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6. Bedaquiline-Resistant Tuberculosis: Dark Clouds on the Horizon

Author

Andres, Sönke, primary, Merker, Matthias, additional, Heyckendorf, Jan, additional, Kalsdorf, Barbara, additional, Rumetshofer, Rudolf, additional, Indra, Alexander, additional, Hofmann-Thiel, Sabine, additional, Hoffmann, Harald, additional, Lange, Christoph, additional, Niemann, Stefan, additional, and Maurer, Florian P., additional

Published
2020
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7. QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe:a Tuberculosis Network European Trialsgroup (TBnet) study

Author

Guglielmetti, Lorenzo, Tiberi, Simon, Burman, Matthew, Kunst, Heinke, Wejse, Christian, Togonidze, Tamar, Bothamley, Graham, Lange, Christoph, Hafizi, Hasan, Kirakosyan, Ohanna, Rumetshofer, Rudolf, Andersen, Åse Bengård, Ravn, Pernille, Kolekar, Shailesh, Dudnyk, Andrii, Belton, Moerida, Dedicoat, Martin, Guglielmetti, Lorenzo, Tiberi, Simon, Burman, Matthew, Kunst, Heinke, Wejse, Christian, Togonidze, Tamar, Bothamley, Graham, Lange, Christoph, Hafizi, Hasan, Kirakosyan, Ohanna, Rumetshofer, Rudolf, Andersen, Åse Bengård, Ravn, Pernille, Kolekar, Shailesh, Dudnyk, Andrii, Belton, Moerida, and Dedicoat, Martin

Published
2018

8. Clinical Management of Multidrug-Resistant Tuberculosis in 16 European Countries

Author

Günther, Gunar, primary, van Leth, Frank, additional, Alexandru, Sofia, additional, Altet, Neus, additional, Avsar, Korkut, additional, Bang, Didi, additional, Barbuta, Raisa, additional, Bothamley, Graham, additional, Ciobanu, Ana, additional, Crudu, Valeriu, additional, Danilovits, Manfred, additional, Dedicoat, Martin, additional, Duarte, Raquel, additional, Gualano, Gina, additional, Kunst, Heinke, additional, de Lange, Wiel, additional, Leimane, Vaira, additional, McLaughlin, Anne-Marie, additional, Magis-Escurra, Cecile, additional, Muylle, Inge, additional, Polcová, Veronika, additional, Popa, Cristina, additional, Rumetshofer, Rudolf, additional, Skrahina, Alena, additional, Solodovnikova, Varvara, additional, Spinu, Victor, additional, Tiberi, Simon, additional, Viiklepp, Piret, additional, and Lange, Christoph, additional

Published
2018
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9. Reply: Benefit of the Shorter Multidrug-Resistant Tuberculosis Treatment Regimen in California and Modified Eligibility Criteria

Author

van Leth, Frank, primary, Günther, Gunar, additional, Hoffmann, Harald, additional, Lange, Christoph, additional, Alexandru, Sofia, additional, Altet, Neus, additional, Avsar, Korkut, additional, Bang, Didi, additional, Barbuta, Raisa, additional, Bothamley, Graham, additional, Ciobanu, Ana, additional, Crudu, Valeriu, additional, Danilovits, Manfred, additional, Dedicoat, Martin, additional, Duarte, Raquel, additional, Fréchet-Jachym, Mathilde, additional, Gualano, Gina, additional, Guglielmetti, Lorenzo, additional, Heyckendorf, Jan, additional, Kalsdorf, Barbara, additional, Kunst, Heinke, additional, de Lange, Wiel, additional, Le Dû, Damien, additional, Leimane, Vaira, additional, van Leth, Frank, additional, Macedo, Rita, additional, Magis-Escurra, Cecile, additional, McLaughlin, Anne-Marie, additional, Muylle, Inge, additional, Olaru, Ioana D., additional, Oliveira, Olena, additional, Polcová, Veronika, additional, Pontali, Emanuele, additional, Popa, Cristina, additional, Robert, Jérôme, additional, Rumetshofer, Rudolf, additional, Skrahina, Alena, additional, Solodovnikova, Varvara, additional, Spinu, Victor, additional, Tiberi, Simon, additional, Veziris, Nicolas, additional, and Viiklepp, Piret, additional

Published
2017
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10. Tuberculosis Guideline for Adults

Author

Schaberg, Tom, Bauer, Torsten, Brinkmann, Folke, Diel, Roland, Feiterna-Sperling, Cornelia, Haas, Walter, Hartmann, Pia, Hauer, Barbara, Heyckendorf, Jan, Lange, Christoph, Nienhaus, Albert, Otto-Knapp, Ralf, Priwitzer, Martin, Richter, Elvira, Rumetshofer, Rudolf, Schenkel, Karl, Schoch, Otto Dagobert, Schoenfeld, Nicolas, Stahlmann, Ralf, Schaberg, Tom, Bauer, Torsten, Brinkmann, Folke, Diel, Roland, Feiterna-Sperling, Cornelia, Haas, Walter, Hartmann, Pia, Hauer, Barbara, Heyckendorf, Jan, Lange, Christoph, Nienhaus, Albert, Otto-Knapp, Ralf, Priwitzer, Martin, Richter, Elvira, Rumetshofer, Rudolf, Schenkel, Karl, Schoch, Otto Dagobert, Schoenfeld, Nicolas, and Stahlmann, Ralf

Abstract

Since 2015 a significant increase in tuberculosis cases is notified in Germany, mostly due to rising numbers of migrants connected to the recent refugee crisis. Because of the low incidence in previous years, knowledge on tuberculosis is more and more limited to specialized centers. However, lung specialist and healthcare workers of other fields have contact to an increasing number of tuberculosis patients. In this situation, guidance for the management of standard therapy and especially for uncommon situations will be essential. This new guideline on tuberculosis in adults gives recommendations on diagnosis, treatment, prevention and prophylaxis. It provides a comprehensive overview over the current knowledge, adapted to the specific situation in Germany. The German Central Committee against Tuberculosis (DZK e.V.) realized this guideline on behalf of the German Respiratory Society (DGP). A specific guideline for tuberculosis in the pediatrics field will be published separately. Compared to the former recommendations of the year 2012, microbiological diagnostics and therapeutic drug management were given own sections. Chapters about the treatment of drug-resistant tuberculosis, tuberculosis in people living with HIV and pharmacological management were extended. This revised guideline aims to be a useful tool for practitioners and other health care providers to deal with the recent challenges of tuberculosis treatment in Germany.

Published
2017

11. Limited Benefit of the New Shorter Multidrug-Resistant Tuberculosis Regimen in Europe [Letters to the Editor]

Author

Lange, Christoph, Duarte, Raquel, Fréchet-Jachym, Mathilde, Guenther, Gunar, Guglielmetti, Lorenzo, Olaru, Ioana D, Oliveira, Olena, Rumetshofer, Rudolf, Veziris, Nicolas, van Leth, Frank, and European MDR-TB database collaboration

Subjects
Europe, Infecções Respiratórias, Treatment Outcome, Clinical Protocols, Tuberculosis, Multidrug-Resistant, Practice Guidelines as Topic, Antitubercular Agents, Eligibility Determination, Humans, World Health Organization, Drug Administration Schedule
Abstract

European MDR-TB database collaboration: Sofia Alexandru, Neus Altet, Korkut Avsar, Didi Bang, Raisa Barbuta, Graham Bothamley, Ana Ciobanu, Valeriu Crudu, Manfred Danilovits, Martin Dedicoat, Raquel Duarte, Mathilde Fréchet-Jachym, Gina Gualano, Lorenzo Guglielmetti, Gunar Günther, Jan Heyckendorf, Barbara Kalsdorf, Heinke Kunst, Christoph Lange, Wiel de Lange, Damien Le Dû, Vaira Leimane, Frank van Leth, Rita Macedo, Cecile Magis-Escurra, Anne-Marie McLaughlin, Inge Muylle, Ioana D Olaru, Olena Oliveira, Veronika Polcová, Emanuele Pontali, Cristina Popa, Jérôme Robert, Rudolf Rumetshofer, Alena Skrahina, Varvara Solodovnikova, Victor Spinu, Simon Tiberi, Nicolas Veziris, Piret Viiklepp European MDR-TB database collaboration: Rita Macedo, INSA, Portugal [Letters to the Editor] Extract: The emergence of multidrug-resistant tuberculosis (MDR-TB), defined as bacillary resistance to at least rifampicin and isoniazid, threatens global TB control. The number of patients notified with MDR-TB worldwide has increased by 261% from 2009 to 2014, and more than one-third of these patients currently live in the European Region of the World Health Organization (WHO). Management of patients with MDR-TB is challenging owing to the long duration of therapy required to achieve a relapse-free cure, complex drug regimens, frequent drug-related adverse events, high costs, suboptimal adherence, and overall low cure rates. [...] info:eu-repo/semantics/publishedVersion

Published
2016

12. S2k-Leitlinie: Tuberkulose im Erwachsenenalter

Author

Schaberg, Tom, additional, Bauer, Torsten, additional, Brinkmann, Folke, additional, Diel, Roland, additional, Feiterna-Sperling, Cornelia, additional, Haas, Walter, additional, Hartmann, Pia, additional, Hauer, Barbara, additional, Heyckendorf, Jan, additional, Lange, Christoph, additional, Nienhaus, Albert, additional, Otto-Knapp, Ralf, additional, Priwitzer, Martin, additional, Richter, Elvira, additional, Rumetshofer, Rudolf, additional, Schenkel, Karl, additional, Schoch, Otto, additional, Schönfeld, Nicolas, additional, and Stahlmann, Ralf, additional

Published
2017
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13. Treatment outcomes of MDR-TB and HIV co-infection in Europe

Author

Magis-Escurra, Cecile, primary, Günther, Gunar, additional, Lange, Christoph, additional, Alexandru, Sofia, additional, Altet, Neus, additional, Avsar, Korkut, additional, Bang, Didi, additional, Barbuta, Raisa, additional, Bothamley, Graham, additional, Ciobanu, Ana, additional, Crudu, Valeriu, additional, Davilovits, Manfred, additional, Dedicoat, Martin, additional, Duarte, Raquel, additional, Gualano, Gina, additional, Kunst, Heike, additional, de Lange, Wiel, additional, Leimane, Vaira, additional, McLaughlin, Anne-Marie, additional, Muylle, Inge, additional, Polcová, Veronika, additional, Popa, Christina, additional, Rumetshofer, Rudolf, additional, Skrahina, Alena, additional, Solodovnikova, Varvara, additional, Spinu, Victor, additional, Tiberi, Simon, additional, Viiklepp, Piret, additional, and van Leth, Frank, additional

Published
2017
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15. Treatment Outcomes in Multidrug-Resistant Tuberculosis

Author

Günther, Gunar, primary, Lange, Christoph, additional, Alexandru, Sofia, additional, Altet, Neus, additional, Avsar, Korkut, additional, Bang, Didi, additional, Barbuta, Raisa, additional, Bothamley, Graham, additional, Ciobanu, Ana, additional, Crudu, Valeriu, additional, Danilovits, Manfred, additional, Dedicoat, Martin, additional, Duarte, Raquel, additional, Gualano, Gina, additional, Kunst, Heinke, additional, de Lange, Wiel, additional, Leimane, Vaira, additional, Magis-Escurra, Cecile, additional, McLaughlin, Anne-Marie, additional, Muylle, Inge, additional, Polcová, Veronika, additional, Popa, Christina, additional, Rumetshofer, Rudolf, additional, Skrahina, Alena, additional, Solodovnikova, Varvara, additional, Spinu, Victor, additional, Tiberi, Simon, additional, Viiklepp, Piret, additional, and van Leth, Frank, additional

Published
2016
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18. False-negative interferon-γ release assay results in active tuberculosis: a TBNET study

Author

de Visser, Veerle, primary, Sotgiu, Giovanni, additional, Lange, Christoph, additional, Aabye, Martine G., additional, Bakker, Marleen, additional, Bartalesi, Filippo, additional, Brat, Kristian, additional, Chee, Cynthia B.E., additional, Dheda, Keertan, additional, Dominguez, Jose, additional, Eyuboglu, Fusun, additional, Ghanem, Maha, additional, Goletti, Delia, additional, Dilektasli, Asli Gorek, additional, Guglielmetti, Lorenzo, additional, Koh, Won-Jung, additional, Latorre, Irene, additional, Losi, Monica, additional, Polanova, Monica, additional, Ravn, Pernille, additional, Ringshausen, Felix C., additional, Rumetshofer, Rudolf, additional, de Souza-Galvão, Maria Luiza, additional, Thijsen, Steven, additional, Bothamley, Graham, additional, and Bossink, Aik, additional

Published
2014
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21. [Tuberculosis Guideline for Adults - Guideline for Diagnosis and Treatment of Tuberculosis including LTBI Testing and Treatment of the German Central Committee (DZK) and the German Respiratory Society (DGP)].

Author

Schaberg T, Bauer T, Brinkmann F, Diel R, Feiterna-Sperling C, Haas W, Hartmann P, Hauer B, Heyckendorf J, Lange C, Nienhaus A, Otto-Knapp R, Priwitzer M, Richter E, Rumetshofer R, Schenkel K, Schoch OD, Schönfeld N, and Stahlmann R

Subjects
AIDS-Related Opportunistic Infections diagnosis, AIDS-Related Opportunistic Infections drug therapy, AIDS-Related Opportunistic Infections epidemiology, AIDS-Related Opportunistic Infections prevention & control, Adult, Antitubercular Agents adverse effects, Bacteriological Techniques, Cross-Sectional Studies, Emigrants and Immigrants statistics & numerical data, Germany, Humans, Refugees statistics & numerical data, Societies, Medical, Tuberculosis, Multidrug-Resistant diagnosis, Tuberculosis, Multidrug-Resistant drug therapy, Tuberculosis, Multidrug-Resistant epidemiology, Tuberculosis, Multidrug-Resistant prevention & control, Tuberculosis, Pulmonary drug therapy, Tuberculosis, Pulmonary epidemiology, Tuberculosis, Pulmonary prevention & control, Antitubercular Agents therapeutic use, Tuberculosis, Pulmonary diagnosis
Abstract

Since 2015 a significant increase in tuberculosis cases is notified in Germany, mostly due to rising numbers of migrants connected to the recent refugee crisis. Because of the low incidence in previous years, knowledge on tuberculosis is more and more limited to specialized centers. However, lung specialist and healthcare workers of other fields have contact to an increasing number of tuberculosis patients. In this situation, guidance for the management of standard therapy and especially for uncommon situations will be essential. This new guideline on tuberculosis in adults gives recommendations on diagnosis, treatment, prevention and prophylaxis. It provides a comprehensive overview over the current knowledge, adapted to the specific situation in Germany. The German Central Committee against Tuberculosis (DZK e. V.) realized this guideline on behalf of the German Respiratory Society (DGP). A specific guideline for tuberculosis in the pediatrics field will be published separately. Compared to the former recommendations of the year 2012, microbiological diagnostics and therapeutic drug management were given own sections. Chapters about the treatment of drug-resistant tuberculosis, tuberculosis in people living with HIV and pharmacological management were extended. This revised guideline aims to be a useful tool for practitioners and other health care providers to deal with the recent challenges of tuberculosis treatment in Germany., Competing Interests: Interessenkonflikt: Siehe Interessenkonflikterklärung auf www.awmf.org, (© Georg Thieme Verlag KG Stuttgart · New York.)

Published
2017
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22. False-negative interferon-γ release assay results in active tuberculosis: a TBNET study.

Author

de Visser V, Sotgiu G, Lange C, Aabye MG, Bakker M, Bartalesi F, Brat K, Chee CB, Dheda K, Dominguez J, Eyuboglu F, Ghanem M, Goletti D, Dilektasli AG, Guglielmetti L, Koh WJ, Latorre I, Losi M, Polanova M, Ravn P, Ringshausen FC, Rumetshofer R, de Souza-Galvão ML, Thijsen S, Bothamley G, and Bossink A

Subjects
Adult, Cross-Sectional Studies, Female, Genetic Variation, Humans, International Cooperation, Logistic Models, Male, Middle Aged, Multivariate Analysis, Regression Analysis, Retrospective Studies, Risk Factors, Surveys and Questionnaires, False Negative Reactions, Interferon-gamma metabolism, Interferon-gamma Release Tests methods, Tuberculosis diagnosis
Published
2015
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