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1. The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration

Author

Senage, Thomas, Paul, Anu, Le Tourneau, Thierry, Fellah-Hebia, Imen, Vadori, Marta, Bashir, Salam, Galiñanes, Manuel, Bottio, Tomaso, Gerosa, Gino, Evangelista, Arturo, Badano, Luigi P, Nassi, Alberto, Costa, Cristina, Cesare, Galli, Manji, Rizwan A, Cueff de Monchy, Caroline, Piriou, Nicolas, Capoulade, Romain, Serfaty, Jean-Michel, Guimbretière, Guillaume, Dantan, Etienne, Ruiz-Majoral, Alejandro, Coste du Fou, Guénola, Leviatan Ben-Arye, Shani, Govani, Liana, Yehuda, Sharon, Bachar Abramovitch, Shirley, Amon, Ron, Reuven, Eliran Moshe, Atiya-Nasagi, Yafit, Yu, Hai, Iop, Laura, Casós, Kelly, Kuguel, Sebastián G, Blasco-Lucas, Arnau, Permanyer, Eduard, Sbraga, Fabrizio, Llatjós, Roger, Moreno-Gonzalez, Gabriel, Sánchez-Martínez, Melchor, Breimer, Michael E, Holgersson, Jan, Teneberg, Susann, Pascual-Gilabert, Marta, Nonell-Canals, Alfons, Takeuchi, Yasuhiro, Chen, Xi, Mañez, Rafael, Roussel, Jean-Christian, Soulillou, Jean-Paul, Cozzi, Emanuele, and Padler-Karavani, Vered

Subjects
Biomedical and Clinical Sciences, Immunology, Heart Disease, Cardiovascular, 5.3 Medical devices, Development of treatments and therapeutic interventions, Animals, Antibody Formation, Aortic Valve, Aortic Valve Stenosis, Bioprosthesis, Calcinosis, Galactose, Humans, Immunoglobulin G, Mice, Polysaccharides, Prospective Studies, Medical and Health Sciences, Biomedical and clinical sciences, Health sciences
Abstract

Bioprosthetic heart valves (BHVs) are commonly used to replace severely diseased heart valves but their susceptibility to structural valve degeneration (SVD) limits their use in young patients. We hypothesized that antibodies against immunogenic glycans present on BHVs, particularly antibodies against the xenoantigens galactose-α1,3-galactose (αGal) and N-glycolylneuraminic acid (Neu5Gc), could mediate their deterioration through calcification. We established a large longitudinal prospective international cohort of patients (n = 1668, 34 ± 43 months of follow-up (0.1-182); 4,998 blood samples) to investigate the hemodynamics and immune responses associated with BHVs up to 15 years after aortic valve replacement. Early signs of SVD appeared in

Published
2022

2. Oxidative Stress in Structural Valve Deterioration: A Longitudinal Clinical Study

Author

Galiñanes, Manuel, primary, Casós, Kelly, additional, Blasco-Lucas, Arnau, additional, Permanyer, Eduard, additional, Máñez, Rafael, additional, Le Tourneau, Thierry, additional, Barquinero, Jordi, additional, Schwartz, Simo, additional, Bottio, Tomaso, additional, Roussel, Jean Christian, additional, Fellah-Hebia, Imen, additional, Sénage, Thomas, additional, Evangelista, Arturo, additional, Badano, Luigi P., additional, Ruiz-Majoral, Alejandro, additional, Galli, Cesare, additional, Padler-Karavani, Vered, additional, Soulillou, Jean-Paul, additional, Vidal, Xavier, additional, Cozzi, Emanuele, additional, and Costa, Cristina, additional

Published
2022
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3. Prognostic impact of late gadolinium enhancement at the right ventricular insertion points in non-ischaemic dilated cardiomyopathy

Author

Claver, Eduard, primary, Di Marco, Andrea, additional, Brown, Pamela Frances, additional, Bradley, Joshua, additional, Nucifora, Gaetano, additional, Ruiz-Majoral, Alejandro, additional, Dallaglio, Paolo Domenico, additional, Rodriguez, Marcos, additional, Comin-Colet, Josep, additional, Anguera, Ignasi, additional, Miller, Christopher A., additional, and Schmitt, Matthias, additional

Published
2022
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4. Prognostic impact of late gadolinium enhancement at the right ventricular insertion points in non-ischaemic dilated cardiomyopathy.

Author

Claver, Eduard, Marco, Andrea Di, Brown, Pamela Frances, Bradley, Joshua, Nucifora, Gaetano, Ruiz-Majoral, Alejandro, Dallaglio, Paolo Domenico, Rodriguez, Marcos, Comin-Colet, Josep, Anguera, Ignasi, Miller, Christopher A, and Schmitt, Matthias

Subjects
EXPERIMENTAL design, RESEARCH, MAGNETIC resonance angiography, RIGHT heart ventricle, RETROSPECTIVE studies, CHEMICAL elements, COMPARATIVE studies, DILATED cardiomyopathy, DESCRIPTIVE statistics, RESEARCH bias, LONGITUDINAL method
Abstract

Aims To evaluate the baseline characteristics and the prognostic implications associated with late gadolinium enhancement limited to the right ventricular insertion points (IP-LGE) or present at both the right ventricular insertion points and the left ventricle (IP&LV-LGE) in non-ischaemic dilated cardiomyopathy (DCM). Methods and results This is a retrospective observational multicentre cohort study including 1165 consecutive patients with DCM evaluated by cardiac magnetic resonance. The primary endpoint included appropriate defibrillator therapies, sustained ventricular tachycardia, resuscitated cardiac arrest, or sudden death. The secondary outcome encompassed heart failure hospitalizations, heart transplant, left ventricular assist device implantation, and end-stage heart failure death. IP-LGE was found in 72 patients (6%), who had clinical characteristics closer to LGE− than to LGE+ patients. During follow-up (median 36 months), none of the IP-LGE patients experienced the primary endpoint. The cumulative incidence of the primary endpoint was similar between IP-LGE and LGE− patients (P = 1), while IP-LGE had significantly lower cumulative incidence when compared with LGE+ patients (P < 0.001). When compared with IP-LGE patients, the cumulative incidence of the secondary endpoint was similar in LGE− cases (P = 0.86) but tended to be higher in LGE+ patients (P = 0.06). Both clinical characteristics and outcomes were similar between IP&LV-LGE patients and the rest of LGE+ cases. Conclusions In a large cohort of DCM patients, IP-LGE was associated with similar outcome when compared with LGE− patients and with significant lower risk of ventricular arrhythmias and sudden death when compared with LGE+ cases. Patients with IP&LV-LGE had clinical characteristics and outcomes similar to the rest of LGE+ cases. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Mural Endocarditis: The GAMES Registry Series and Review of the Literature

Author

Gutiérrez-Villanueva, Andrea, Muñoz, Patricia, Delgado-Montero, Antonia, Olmedo-Samperio, María, de Alarcón, Arístides, Gutiérrez-Carretero, Encarnación, Zarauza, Jesús, García i Pares, Delia, Goenaga, Miguel Ángel, Ojeda-Burgos, Guillermo, Goikoetxea-Agirre, Ane Josune, Reguera-Iglesias, José Mª, Ramos, Antonio, Fernández-Cruz, Ana, Fernández-Sánchez, Fernando, García de Lomas, José Mª, Rosas, Gabriel, de la Torre Lima, Javier, Bereciartua, Elena, Blanco-Vidal, María José, Blanco, Roberto, Boado, María Victoria, Campaña-Lázaro, Marta, Crespo, Alejandro, Guio-Carrión, Laura, del Álamo Martínez-Lagos, Mikel, Euba-Ugarte, Gorane, Goikoetxea, Ane Josune, Ibarrola-Hierro, Marta, Iruretagoyena, José Ramón, Irurzun-Zuazabal, Josu, López-Soria, Leire, Montejo, Miguel, Nieto, Javier, Rodrigo, David, Rodríguez, Regino, Vitoria, Yolanda, Voces, Roberto, García-López, Mª Victoria, Georgieva, Radka Ivanova, Ojeda, Guillermo, Rodríguez-Bailón, Isabel, Ruiz-Morales, Josefa, Azkune-Galparsoro, Harkaitz, Berritu-Boronat, Elisa, Bustinduy-Odriozola, Mª Jesús, del Bosque Martín, Cristina, Echeverría, Tomás, Eizaguirre-Yarza, Alberto, Fuentes, Ana, Goyeneche del Río, Muskilda, Granda-Bauza, Ángela, Iribarren, José Antonio, Kortajarena-Urkola, Xabier, Pérez-Moreiras López, José Ignacio, Rengel-Jiménez, Ainhoa, Reviejo, Karlos, Sáez-Berbejillo, Alberto, Sánchez-Haza, Elou, Sebastián-Alda, Rosa, Solla-Ruiz, Itziar, Unamuno-Ugartemendia, Irati, Anza, Diego Vicente, Villanueva-Benito, Iñaki, Zabalo-Arrieta, Mar, Carrasco, Rafael, Climent, Vicente, Llamas, Patricio, Merino, Esperanza, Plazas, Joaquín, Reus, Sergio, Álvarez, Nemesio, Bravo-Ferrer, José María, Castelo, Laura, Cuenca, José, Llinares, Pedro, Miguez-Rey, Enrique, Rodríguez-Mayo, María, Sánchez, Efrén, Sousa-Regueiro, Dolores, Martínez, Francisco Javier, del Mar Alonso, null, Castro, Beatriz, Delgado-Melian, Teresa, Fernández-Sarabia, Javier, García-Rosado, Dácil, González-González, Julia, Lacalzada, Juan, Lorenzo de la Peña, Lissete, Pérez-Ramírez, Alina, Prada-Arrondo, Pablo, Rodríguez-Moreno, Fermín, Plata-Ciezar, Antonio, Asensi-Álvarez, Víctor, Costas, Carlos, de la Hera, Jesús, Fernández-Suárez, Jonnathan, Iglesias-Fraile, Lisardo, León-Arguero, Víctor, López-Menéndez, José, Mencia-Bajo, Pilar, Morales, Carlos, Moreno-Torrico, Alfonso, Palomo, Carmen, Paya-Martínez, Begoña, Rodríguez-Esteban, Ángeles, Rodríguez-García, Raquel, Telenti-Asensio, Mauricio, Almela, Manuel, Ambrosioni, Juan, Azqueta, Manuel, Brunet, Mercè, Bodro, Marta, Cartañá, Ramón, Falces, Carlos, Fita, Guillermina, Fuster, David, García de la Mària, Cristina, Hernández-Meneses, Marta, Llopis-Pérez, Jaume, Marco, Francesc, Miró, José M., Moreno, Asunción, Nicolás, David, Ninot, Salvador, Quintana, Eduardo, Paré, Carlos, Pereda, Daniel, Pericás, Juan M., Pomar, José L., Ramírez, José, Rovira, Irene, Sandoval, Elena, Sitges, Marta, Soy, Dolors, Téllez, Adrián, Tolosana, José M., Vidal, Bárbara, Vila, Jordi, Adán, Iván, Alonso, Juan Carlos, Álvarez-Uría, Ana, Bermejo, Javier, Bouza, Emilio, Cuerpo-Caballero, Gregorio, González-Mansilla, Ana, García-Leoni, Mª Eugenia, Gargallo, Esther, González-Ramallo, Víctor, Kestler-Hernández, Martha, Hualde, Amaia Mari, Machado, Marina, Marín, Mercedes, Martínez-Sellés, Manuel, Olmedo, María, Pedraz, Álvaro, Pinilla, Blanca, Pinto, Ángel, Rincón, Cristina, Rodríguez-Abella, Hugo, Rodríguez-Créixems, Marta, Segado, Antonio, Toledo, Neera, Valerio, Maricela, Vázquez, Pilar, Verde-Moreno, Eduardo, Antorrena, Isabel, Loeches, Belén, Moreno, Mar, Ramírez, Ulises, Rial-Bastón, Verónica, Romero, María, Rosillo, Sandra, Agüero-Balbín, Jesús, Amado, Cristina, Armiñanzas-Castillo, Carlos, Arnaiz, Ana, Arnaiz de las Revillas, Francisco, Cobo Belaustegui, Manuel, Fariñas, María Carmen, Fariñas-Álvarez, Concepción, Fernández-Sampedro, Marta, García, Iván, González-Rico, Claudia, Gutierrez-Fernandez, Laura, Gutiérrez-Cuadra, Manuel, Gutiérrez-Díez, José, Pajarón, Marcos, Parra, José Antonio, Teira, Ramón, Calderón-Parra, Jorge, Cobo, Marta, Domínguez, Fernando, García-Pavía, Pablo, Ramos-Martínez, Antonio, Sánchez-Romero, Isabel, Centella, Tomasa, Hermida, José Manuel, Moya, José Luis, Martín-Dávila, Pilar, Navas, Enrique, Oliva, Enrique, del Río, Alejandro, Rodríguez-Roda Stuart, Jorge, Ruiz, Soledad, Hidalgo-Tenorio, Carmen, Almendro-Delia, Manuel, Araji, Omar, Barquero, José Miguel, Calvo-Jambrina, Román, de Cueto, Marina, Gálvez-Acebal, Juan, Méndez, Irene, Morales, Isabel, López-Cortés, Luis Eduardo, Lepe, José Antonio, López-Haldón, José, Luque-Márquez, Rafael, Marín, Guillermo, Ortiz-Carrellán, Antonio, Sánchez-Domínguez, Eladio, Alonso, Luis Javier, Azcárate, Pedro, Azcona-Gutiérrez, José Manuel, Blanco, José Ramón, Cabrera-Villegas, Antonio, García-Álvarez, Lara, García-García, Concepción, Oteo, José Antonio, de Benito, Natividad, Gurguí, Mercé, Pacho, Cristina, Pericas, Roser, Pons, Guillem, Álvarez, null, Fernández, null, Martínez, Amparo, Prieto, null, Regueiro, Benito, Tijeira, null, Vega, Marino, Canut-Blasco, Andrés, Mollar, José Cordo, Gainzarain-Arana, Juan Carlos, García-Uriarte, Oscar, Martín-López, Alejandro, Ortiz de Zárate, Zuriñe, Urturi-Matos, José Antonio, Sánchez-Porto, Antonio, Úbeda-Iglesias, Alejandro, Arribas-Leal, José Mª, García-Vázquez, Elisa, Hernández-Torres, Alicia, Blázquez, Ana, de la Morena Valenzuela, Gonzalo, Alonso, Ángel, Aramburu, Javier, Calvo, Felicitas Elena, Moreno-Rodríguez, Anai, Tarabini-Castellani, Paola, Heredero-Gálvez, Eva, Maicas-Bellido, Carolina, Largo-Pau, José, Sepúlveda, Mª Antonia, Toledano-Sierra, Pilar, Iqbal-Mirza, Sadaf Zafar, Cascales-Alcolea, Eva, Keituqwa-Yañez, Ivan, Navarro-Martínez, Julián, Peláez-Ballesta, Ana, Moreno-Escobar, Eduardo, Peña-Monje, Alejandro, Sánchez-Cabrera, Valme, Vinuesa-García, David, Arrizabalaga-Asenjo, María, Cifuentes-Luna, Carmen, Núñez-Morcillo, Juana, Pérez-Seco, Mª Cruz, Villoslada-Gelabert, Aroa, Aured-Guallar, Carmen, Fernández-Abad, Nuria, García-Mangas, Pilar, Matamala-Adell, Marta, Palacián-Ruiz, Mª Pilar, Porres, Juan Carlos, Alcaraz-Vidal, Begoña, Cobos-Trigueros, Nazaret, Del Amor Espín, María Jesús, Giner-Caro, José Antonio, Jiménez-Sánchez, Roberto, Jimeno-Almazán, Amaya, Ortín-Freire, Alejandro, Viqueira-González, Monserrat, Pericás-Ramis, Pere, Ribas-Blanco, Mª Ángels, Ruiz de Gopegui Bordes, Enrique, Vidal-Bonet, Laura, Bellón-Munera, Mª Carmen, Escribano-Garaizabal, Elena, Tercero-Martínez, Antonia, Segura-Luque, Juan Carlos, Badía, Cristina, Boix-Palop, Lucía, Xercavins, Mariona, Ibars, Sónia, Bosch, Xerach, Gómez-Nebreda, Eloy, Horcajada-Herrera, Ibalia, Menduiña-Gallego, Irene, Pulido, Imanol, Marrero-Santiago, Héctor, de Miguel Martínez, Isabel, Pisos-Álamo, Elena, Aguilar-Blanco, Eva Mª, Catalán-González, Mercedes, Corres-Peiretti, María Angélica, Eixerés-Esteve, Andrea, Domínguez-Pérez, Laura, de Cossío Tejido, Santiago, Galván-Román, Francisco, García-Robles, José Antonio, López-Medrano, Francisco, López-Gude, Mª Jesús, Orellana-Miguel, Mª Ángeles, Pilkington, Patrick, Revilla-Ostalaza, Yolanda, Morales, Juan Ruiz, Ruiz-Solís, Sebastián, Collado, Ana Sabín, Sánchez-Fernández, Marcos, Rallo, Javier Solera, Martín, Jorge Solís, Cuervo, Guillermo, Escrihuela-Vidal, Francesc, Carratalà, Jordi, Grau, Inmaculada, Grillo, Sara, Ardanuy, Carmen, Berbel, Dámaris, Sánchez-Salado, José Carlos, Alegre, Oriol, Ruiz-Majoral, Alejandro, Sbraga, Fabrizio, Blasco, Arnau, Sánchez, Laura Gracia, Sánchez-Rodríguez, Iván, Álvarez, Beatriz, Cabello-Úbeda, Alfonso, Fernández-Roblas, Ricardo, Navas-Lobato, Miguel Ángel, Pello, Ana María, de la Peña Triguero, Mireia, Figueroa-Cerón, Ruth Esther, Ruiz-Gómez, Lara, Ble, Mireia, Horcajada-Gallego, Juan Pablo, Ginel, Antonio José, López, Inmaculada, Mas, Alexandra, Mestres, Antoni, Molina, Lluís, Serrat, Ramón, Ribas, Núria, Sánchez, Francisca, Silverio, Ana, Suárez, Marina, Sorlí, Luisa, Recasens, Lluís, Taurón, Manuel, 0000-0003-1189-1120, and Universidad de Cantabria

Subjects
Microbiology (medical), medicine.medical_specialty, medicine.medical_treatment, Charlson index, Infections, Hospital patients, Mural, Internal medicine, medicine, Endocarditis, Malalts hospitalitzats, business.industry, Brief Report, medicine.disease, Infeccions, Transplantation, Catheter, Non-valvular endocarditis, Infectious Diseases, Infective endocarditis, Etiology, Hemodialysis, Complication, business, human activities
Abstract

Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES)., [Introduction] Mural infective endocarditis (MIE) is a rare type of endovascular infection. We present a comprehensive series of patients with mural endocarditis., [Methods] Patients with infectious endocarditis (IE) from 35 Spanish hospitals were prospectively included in the GAMES registry between 2008 and 2017. MIEs were compared to non-MIEs. We also performed a literature search for cases of MIE published between 1979 and 2019 and compared them to the GAMEs series., [Results] Twenty-seven MIEs out of 3676 IEs were included. When compared to valvular IE (VIE) or device-associated IE (DIE), patients with MIE were younger (median age 59 years, p, [Conclusion] MIE is a rare entity. It is often a complication of catheter use, particularly in immunocompromised and hemodialysis patients. Fungal etiology is common. Mortality is similar to other IEs.

Published
2021

8. A Contemporary Picture of Enterococcal Endocarditis

Author

Pericàs, Juan M., primary, Llopis, Jaume, additional, Muñoz, Patricia, additional, Gálvez-Acebal, Juan, additional, Kestler, Martha, additional, Valerio, Maricela, additional, Hernández-Meneses, Marta, additional, Goenaga, Miguel Á., additional, Cobo-Belaustegui, Manuel, additional, Montejo, Miguel, additional, Ojeda-Burgos, Guillermo, additional, Sousa-Regueiro, M. Dolores, additional, de Alarcón, Arístides, additional, Ramos-Martínez, Antonio, additional, Miró, José M., additional, Sánchez, Fernando Fernández, additional, Noureddine, Mariam, additional, Rosas, Gabriel, additional, de la Torre Lima, Javier, additional, Blanco, Roberto, additional, Boado, María Victoria, additional, Campaña Lázaro, Marta, additional, Crespo, Alejandro, additional, Goikoetxea, Josune, additional, Iruretagoyena, José Ramón, additional, Irurzun Zuazabal, Josu, additional, López-Soria, Leire, additional, Nieto, Javier, additional, Rodrigo, David, additional, Rodríguez, Regino, additional, Vitoria, Yolanda, additional, Voces, Roberto, additional, García López, Ma Victoria, additional, Georgieva, Radka Ivanova, additional, Ojeda, Guillermo, additional, Rodríguez Bailón, Isabel, additional, Ruiz Morales, Josefa, additional, María Cuende, Ana, additional, Echeverría, Tomás, additional, Fuerte, Ana, additional, Gaminde, Eduardo, additional, Goenaga, Miguel Ángel, additional, Idígoras, Pedro, additional, Antonio Iribarren, José, additional, Izaguirre Yarza, Alberto, additional, Kortajarena Urkola, Xabier, additional, Reviejo, Carlos, additional, Carrasco, Rafael, additional, Climent, Vicente, additional, Llamas, Patricio, additional, Merino, Esperanza, additional, Plazas, Joaquín, additional, Reus, Sergio, additional, Álvarez, Nemesio, additional, Bravo-Ferrer, José María, additional, Castelo, Laura, additional, Cuenca, José, additional, Llinares, Pedro, additional, Miguez Rey, Enrique, additional, Rodríguez Mayo, María, additional, Sánchez, Efrén, additional, Sousa Regueiro, Dolores, additional, Javier Martínez, Francisco, additional, Alonso, Ma del Mar, additional, Castro, Beatriz, additional, García Rosado, Dácil, additional, Durán, Ma del Carmen, additional, Miguel Gómez, Ma Antonia, additional, Lacalzada, Juan, additional, Nassar, Ibrahim, additional, Plata Ciezar, Antonio, additional, Reguera Iglesias, José Ma, additional, Asensi Álvarez, Víctor, additional, Costas, Carlos, additional, de la Hera, Jesús, additional, Fernández Suárez, Jonnathan, additional, Iglesias Fraile, Lisardo, additional, León Arguero, Víctor, additional, López Menéndez, José, additional, Mencia Bajo, Pilar, additional, Morales, Carlos, additional, Moreno Torrico, Alfonso, additional, Palomo, Carmen, additional, Paya Martínez, Begoña, additional, Rodríguez Esteban, Ángeles, additional, Rodríguez García, Raquel, additional, Telenti Asensio, Mauricio, additional, Almela, Manuel, additional, Ambrosioni, Juan, additional, Azqueta, Manuel, additional, Brunet, Mercè, additional, Bodro, Marta, additional, Cartañá, Ramón, additional, Falces, Carlos, additional, Fita, Guillermina, additional, Fuster, David, additional, García de la Mària, Cristina, additional, García-Pares, Delia, additional, Llopis Pérez, Jaume, additional, Marco, Francesc, additional, Moreno, Asunción, additional, Nicolás, David, additional, Ninot, Salvador, additional, Quintana, Eduardo, additional, Paré, Carlos, additional, Pereda, Daniel, additional, Pericás, Juan M., additional, Pomar, José L., additional, Ramírez, José, additional, Rovira, Irene, additional, Sandoval, Elena, additional, Sitges, Marta, additional, Soy, Dolors, additional, Téllez, Adrián, additional, Tolosana, José M., additional, Vidal, Bárbara, additional, Vila, Jordi, additional, Adán, Iván, additional, Bermejo, Javier, additional, Bouza, Emilio, additional, Celemín, Daniel, additional, Cuerpo Caballero, Gregorio, additional, Delgado Montero, Antonia, additional, García Mansilla, Ana, additional, García Leoni, Ma Eugenia, additional, González Ramallo, Víctor, additional, Kestler Hernández, Martha, additional, Hualde, Amaia Mari, additional, Marín, Mercedes, additional, Martínez-Sellés, Manuel, additional, Rincón, Cristina, additional, Rodríguez-Abella, Hugo, additional, Rodríguez-Créixems, Marta, additional, Pinilla, Blanca, additional, Pinto, Ángel, additional, Vázquez, Pilar, additional, Verde Moreno, Eduardo, additional, Antorrena, Isabel, additional, Loeches, Belén, additional, Martín Quirós, Alejandro, additional, Moreno, Mar, additional, Ramírez, Ulises, additional, Rial Bastón, Verónica, additional, Romero, María, additional, Saldaña, Araceli, additional, Agüero Balbín, Jesús, additional, Armiñanzas Castillo, Carlos, additional, Arnaiz, Ana, additional, Arnaiz de las Revillas, Francisco, additional, Cobo Belaustegui, Manuel, additional, Fariñas, María Carmen, additional, Fariñas-Álvarez, Concepción, additional, Gómez Izquierdo, Rubén, additional, García, Iván, additional, González Rico, Claudia, additional, Gutiérrez-Cuadra, Manuel, additional, Gutiérrez Díez, José, additional, Pajarón, Marcos, additional, Parra, José Antonio, additional, Teira, Ramón, additional, Zarauza, Jesús, additional, Calderón Parra, Jorge, additional, Cobo, Marta, additional, Domínguez, Fernando, additional, Fortaleza, Alberto, additional, García Pavía, Pablo, additional, González, Jesús, additional, Fernández Cruz, Ana, additional, Múñez, Elena, additional, Ramos, Antonio, additional, Sánchez Romero, Isabel, additional, Centella, Tomasa, additional, Hermida, José Manuel, additional, Moya, José Luis, additional, Martín-Dávila, Pilar, additional, Navas, Enrique, additional, Oliva, Enrique, additional, del Río, Alejandro, additional, Rodríguez-Roda Stuart, Jorge, additional, Ruiz, Soledad, additional, Hidalgo Tenorio, Carmen, additional, Almendro Delia, Manuel, additional, Araji, Omar, additional, Barquero, José Miguel, additional, Calvo Jambrina, Román, additional, de Cueto, Marina, additional, Gálvez Acebal, Juan, additional, Méndez, Irene, additional, Morales, Isabel, additional, López-Cortés, Luis Eduardo, additional, García, Emilio, additional, Haro, Juan Luis, additional, Lepe, José Antonio, additional, López, Francisco, additional, Luque, Rafael, additional, Alonso, Luis Javier, additional, Azcárate, Pedro, additional, Azcona Gutiérrez, José Manuel, additional, Blanco, José Ramón, additional, Cabrera Villegas, Antonio, additional, García-Álvarez, Lara, additional, Oteo, José Antonio, additional, Sanz, Mercedes, additional, de Benito, Natividad, additional, Gurguí, Mercé, additional, Pacho, Cristina, additional, Pericas, Roser, additional, Pons, Guillem, additional, Álvarez, M., additional, Fernández, A.L., additional, Martínez, Amparo, additional, Prieto, A., additional, Regueiro, Benito, additional, Tijeira, E., additional, Vega, Marino, additional, Canut Blasco, Andrés, additional, Cordo Mollar, José, additional, Gainzarain Arana, Juan Carlos, additional, García Uriarte, Oscar, additional, Martín López, Alejandro, additional, Ortiz de Zárate, Zuriñe, additional, Urturi Matos, José Antonio, additional, Gloria, García-Domínguez, additional, Antonio, Sánchez-Porto, additional, Arribas Leal, José Ma, additional, García Vázquez, Elisa, additional, Hernández Torres, Alicia, additional, Blázquez, Ana, additional, de la Morena Valenzuela, Gonzalo, additional, Alonso, Ángel, additional, Aramburu, Javier, additional, Calvo, Felicitas Elena, additional, Moreno Rodríguez, Anai, additional, Tarabini-Castellani, Paola, additional, Heredero Gálvez, Eva, additional, Maicas Bellido, Carolina, additional, Largo Pau, José, additional, Sepúlveda, Ma Antonia, additional, Toledano Sierra, Pilar, additional, Iqbal-Mirza, Sadaf Zafar, additional, Cascales Alcolea, Eva, additional, Keituqwa Yañez, Ivan, additional, Martínez, Julián Navarro, additional, Ballesta, Ana Peláez, additional, Moreno Escobar, Eduardo, additional, Peña Monje, Alejandro, additional, Sánchez Cabrera, Valme, additional, Vinuesa García, David, additional, Arrizabalaga Asenjo, María, additional, Cifuentes Luna, Carmen, additional, Núñez Morcillo, Juana, additional, Pérez Seco, Ma Cruz, additional, Villoslada Gelabert, Aroa, additional, Aured Guallar, Carmen, additional, Fernández Abad, Nuria, additional, García Mangas, Pilar, additional, Matamala Adell, Marta, additional, Palacián Ruiz, Ma Pilar, additional, Porres, Juan Carlos, additional, Alcaraz Vidal, Begoña, additional, Cobos Trigueros, Nazaret, additional, Del Amor Espín, María Jesús, additional, Giner Caro, José Antonio, additional, Jiménez Sánchez, Roberto, additional, Jimeno Almazán, Amaya, additional, Ortín Freire, Alejandro, additional, Viqueira González, Monserrat, additional, Pericás Ramis, Pere, additional, Ribas Blanco, Ma Ángels, additional, Ruiz de Gopegui Bordes, Enrique, additional, Vidal Bonet, Laura, additional, Bellón Munera, Ma Carmen, additional, Escribano Garaizabal, Elena, additional, Tercero Martínez, Antonia, additional, Segura Luque, Juan Carlos, additional, Badía, Cristina, additional, Boix Palop, Lucía, additional, Xercavins, Mariona, additional, Ibars, Sónia, additional, Nebreda, Eloy Gómez, additional, Horcajada Herrera, Ibalia, additional, Menduiña Gallego, Irene, additional, Marrero Santiago, Héctor, additional, de Miguel Martínez, Isabel, additional, Pisos Álamo, Elena, additional, Díaz Pedroche, Carmen, additional, Chaves, Fernando, additional, de Cossío, Santiago, additional, López Medrano, Francisco, additional, López, Ma Jesús, additional, Solera, Javier, additional, Solís, Jorge, additional, Ardanuy, Carmen, additional, Cuervo Requena, Guillermo, additional, Grillo, Sara, additional, and Ruiz Majoral, Alejandro, additional

Published
2020
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10. Twenty-Year Secular Trends in Infective Endocarditis in a Teaching Hospital

Author

Cuervo, Guillermo, primary, Rombauts, Alexander, additional, Caballero, Queralt, additional, Grau, Immaculada, additional, Pujol, Miquel, additional, Ardanuy, Carmen, additional, Berbel, Dámaris, additional, Gudiol, Carlota, additional, Sánchez-Salado, Jose Carlos, additional, Ruiz-Majoral, Alejandro, additional, Sbraga, Fabrizio, additional, Gracia-Sánchez, Laura, additional, Peña, Carmen, additional, and Carratalà, Jordi, additional

Published
2018
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12. Prognostic impact of late gadolinium enhancement at the right ventricular insertion points in non-ischaemic dilated cardiomyopathy.

Author

Claver E, Di Marco A, Brown PF, Bradley J, Nucifora G, Ruiz-Majoral A, Dallaglio PD, Rodriguez M, Comin-Colet J, Anguera I, Miller CA, and Schmitt M

Subjects
Humans, Prognosis, Heart Ventricles diagnostic imaging, Contrast Media, Gadolinium, Cohort Studies, Magnetic Resonance Imaging, Cine methods, Death, Sudden, Predictive Value of Tests, Cardiomyopathy, Dilated diagnostic imaging, Cardiomyopathy, Dilated therapy, Cardiomyopathy, Dilated complications, Heart Failure complications
Abstract

Aims: To evaluate the baseline characteristics and the prognostic implications associated with late gadolinium enhancement limited to the right ventricular insertion points (IP-LGE) or present at both the right ventricular insertion points and the left ventricle (IP&LV-LGE) in non-ischaemic dilated cardiomyopathy (DCM)., Methods and Results: This is a retrospective observational multicentre cohort study including 1165 consecutive patients with DCM evaluated by cardiac magnetic resonance. The primary endpoint included appropriate defibrillator therapies, sustained ventricular tachycardia, resuscitated cardiac arrest, or sudden death. The secondary outcome encompassed heart failure hospitalizations, heart transplant, left ventricular assist device implantation, and end-stage heart failure death. IP-LGE was found in 72 patients (6%), who had clinical characteristics closer to LGE- than to LGE+ patients. During follow-up (median 36 months), none of the IP-LGE patients experienced the primary endpoint. The cumulative incidence of the primary endpoint was similar between IP-LGE and LGE- patients (P = 1), while IP-LGE had significantly lower cumulative incidence when compared with LGE+ patients (P < 0.001). When compared with IP-LGE patients, the cumulative incidence of the secondary endpoint was similar in LGE- cases (P = 0.86) but tended to be higher in LGE+ patients (P = 0.06). Both clinical characteristics and outcomes were similar between IP&LV-LGE patients and the rest of LGE+ cases., Conclusions: In a large cohort of DCM patients, IP-LGE was associated with similar outcome when compared with LGE- patients and with significant lower risk of ventricular arrhythmias and sudden death when compared with LGE+ cases. Patients with IP&LV-LGE had clinical characteristics and outcomes similar to the rest of LGE+ cases., Competing Interests: Conflict of interest: P.F.B. received a fellowship salary support grant from Alliance Medical. There is no other conflict of interest for the present study., (© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For permissions, please email: journals.permissions@oup.com.)

Published
2023
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