49 results on '"Ruilin Meng"'
Search Results
2. The association between long-term exposure to ambient formaldehyde and respiratory mortality risk: A national study in China
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Siwen Yu, Qijiong Zhu, Min Yu, Chunliang Zhou, Ruilin Meng, Guoxia Bai, Biao Huang, Yize Xiao, Wei Wu, Yanfang Guo, Juanjuan Zhang, Weiling Tang, Jiahong Xu, Shuru Liang, Zhiqing Chen, Guanhao He, Wenjun Ma, and Tao Liu
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Formaldehyde ,Air pollution ,Respiratory mortality ,China ,Environmental pollution ,TD172-193.5 ,Environmental sciences ,GE1-350 - Abstract
Introduction: While ambient formaldehyde (HCHO) concentrations are increasing worldwide, there was limited research on its health effects. Objectives: To assess the association of long-term exposure to ambient HCHO with the risk of respiratory (RESP) mortality and the associated mortality burden in China. Methods: Annual and seasonal RESP death and tropospheric HCHO vertical columns data were collected in 466 counties/districts across China during 2013–2016. A difference-in-differences approach combined with a generalized linear mixed-effects regression model was employed to assess the exposure-response association between long-term ambient HCHO exposure and RESP mortality risk. Additionally, we computed the attributable fraction (AF) to gauge the proportion of RESP mortality attributable to HCHO exposure. Results: This analysis encompassed 560,929 RESP deaths. The annual mean ambient HCHO concentration across selected counties/districts was 8.02×1015 ± 2.22×1015 molec.cm−2 during 2013–2016. Each 1.00×1015 molec.cm−2 increase in ambient HCHO was associated with a 1.61 % increase [excess risk (ER), 95 % confidence interval (CI): 1.20 %, 2.03 %] in the RESP mortality risk. The AF of RESP mortality attributable to HCHO was 12.16 % (95 %CI:9.33 %, 14.88 %), resulting in an annual average of 125,422 (95 %CI:96,404, 153,410) attributable deaths in China. Stratified analyses suggested stronger associations in individuals aged ≥65 years old (ER=1.87 %, 95 %CI:1.43 %, 2.32 %), in cold seasons (ER=1.00 %, 95 %CI:0.56 %, 1.44 %), in urban areas (ER=1.65 %, 95 %CI:1.15 %, 2.16 %), and in chronic obstructive pulmonary disease patients (ER=1.95 %, 95 %CI:1.42 %, 2.48 %). Conclusions: This study suggested that long-term HCHO exposure may significantly increase the risk of RESP mortality, leading to a substantial mortality burden. Targeted measures should be implemented to control ambient HCHO pollution promptly.
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- 2024
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3. Projecting future minimum mortality temperature in China
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Lifang Luo, Guanhao He, Ruilin Meng, Tao Liu, Min Yu, Yize Xiao, Biao Huang, Chunliang Zhou, Haoming Zhang, Zhulin Hou, Xiaojun Xu, Weiwei Gong, Mingfang Qin, Jianxiong Hu, Jianpeng Xiao, Zuhua Rong, Wenbiao Hu, Cunrui Huang, Zhoupeng Ren, and Wenjun Ma
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Temperature ,Minimum mortality temperature ,Adaptation ,Projection ,Environmental pollution ,TD172-193.5 ,Environmental sciences ,GE1-350 - Abstract
Minimum mortality temperature (MMT) increases with global warming due to climate adaptation, which is crucial for the precise assessment of mortality burden attributed to climate change. Nevertheless, forecasting future MMT poses a challenge given the unavailability of future mortality data. Here, we attempted to develop a novel approach to project future MMT. First, we estimated the MMT of 334 locations in China using a distributed lag nonlinear model. Then, meta regression models were applied to investigate the associations between MMT and several temperature variables(Most Frequent Temperature(MFT), average daily mean temperature, average daily minimum temperature, average daily maximum temperature and percentiles of temperature from 1st to 100th). A generalized linear regression model was employed to investigate whether significant differences existed in the relationships between MMT and temperature from the 1st to the 100th percentile. Finally, an optional indicator of MMT for projecting future values was identified. Our results indicated that temperatures in the 85th to 89th percentiles were closely associated with MMT, with the 88th percentile temperature serving as the most effective indicator, as confirmed by meta-regression models. Using the 88th percentile of temperature as alternative indicator of MMT, compared with the period of 2006–2015, the projected MMT in most districts and counties in China tended to rise under three representative concentration pathways (RCPs) in the 2030 s (2030–2039), 2060 s (2060–2069), and 2090 s (2090–2099). Our findings provide some insight to project future MMT for assessing mortality burden related to temperature change driven by global warming.
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- 2024
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4. Prevalence and influencing factors of stroke in residents aged 40 years and older in Guangdong province, 2020: a cross- sectional survey
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Mengyan OU, Ruilin MENG, Dandan PENG, Ye WANG, Xiaojun XU, Xueyan ZHENG, Xiuling SONG, Ni XIAO, and Chuan LI
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stroke ,prevalence ,influencing factor ,residents aged 40 years and above ,guangdong province ,Public aspects of medicine ,RA1-1270 - Abstract
ObjectiveTo investigate the prevalence and influencing factors of stroke in residents aged 40 years and older in Guangdong province for developing stroke prevention and control policies. MethodsTotally 21 176 permanent residents aged 40 years and older were recruited with multistage random cluster sampling in urban and rural regions of 5 municipalities in Guangdong province for a survey conducted during July – December 2020. All the participants undertook face-to-face interview with a questionnaire designed by domestic experts, physical examination and laboratory tests. Unconditional multivariate logistic regression model was used to analyze influencing factors of stroke. ResultsAmong 16 993 participants surveyed effectively, 361 stroke sufferers were identified and the crude and age-adjusted stroke prevalence were 2 124.40/100 000 and 1 725.25/100 000, respectively. Multivariate unconditional logistic regression analysis revealed following risk factors of stroke among the participants: ≥ 50 years old, smoking, lack of physical activity, family history of stroke, hypertension, diabetes, dyslipidemia, high homocysteine, and atrial fibrillation or valvular heart disease; while, being female and with an individual annual income of 5 000 – 10 000 or more than 20 000 Chinese yuan were protective factors against stroke. ConclusionThe prevalence of stroke was relatively low and influenced mainly by gender, age, annual personal income, smoking, lack of physical activity, family history of stroke, hypertension, diabetes, dyslipidemia, high homocysteine, atrial fibrillation or valvular heart disease among urban and rural residents aged 40 years and older in Guangdong province.
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- 2024
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5. Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China
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Weiling Tang, Min Yu, Guoxia Bai, Chunliang Zhou, Ruilin Meng, Biao Huang, Weiwei Gong, Zhulin Hou, Jianxiong Hu, Guanhao He, Lifeng Lin, Yanfang Guo, Juanjuan Zhang, Qijiong Zhu, Zhiqing Chen, Siwen Yu, Yuan Zheng, Yayi Li, Jiahong Xu, Xiaofeng Liang, Wenjun Ma, and Tao Liu
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Air pollution ,Ambient ozone ,Respiratory mortality ,Disease burden ,Technology ,Medicine - Abstract
Background: Although the health impacts of ambient ozone (O3) have been widely assessed, studies simultaneously investigating the acute and chronic effects of O3 on mortality from respiratory diseases (RESP) are scarce. Methods: We extracted personal information of all recorded deaths from RESP throughout 2013–2018 in six provinces in China. The daily, seasonal, and annual mean air pollutant concentrations at the township/subdistrict level were estimated by a random forest model. The acute association between the maximum daily average 8h ozone (MDA8 O3) and RESP mortality was examined by a time-stratified case-crossover study design, and the chronic association was estimated by a difference-in-differences (DID) analysis approach. We also calculated the attributable fraction (AF) of RESP mortality attributable to MDA8 O3. Results: There were 1,034,226 RESP deaths included in this study. The excess risks (ERs) of overall RESP mortality for each 10 μg/m3 increase in short-term (lag03 days) and long-term (one-year average) exposure to MDA8 O3 were 0.38 % (95%CI: 0.26 %, 0.50 %) and 4.37 % (3.91 %, 4.84 %), respectively. The AFs of overall RESP mortality ascribed to short- and long-term MDA8 O3 exposures were 3.00 % (2.03 %, 3.95 %) and 29.45 % (26.86 %, 31.95 %), respectively. The average annual number of RESP deaths attributable to short-term MDA8 O3 exposure was 30,790 and 302,254 were attributable to long-term MDA8 O3 exposure across China during 2013–2018. Conclusion: Both short- and long-term exposure to ambient MDA8 O3 were positively associated with RESP mortality, and long-term exposure to MDA8 O3 may lead to a greater RESP mortality burden than short-term exposure to MDA8 O3.
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- 2024
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6. Proportion and number of incident cancer deaths in coronary artery disease
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Jin Liu, Shiqun Chen, Yang Zhou, Haozhang Huang, Qiang Li, Yan Liang, Shaohong Dong, Xiaoyu Huang, Liling Chen, Xueyan Zheng, Ruilin Meng, Congzhuo Jia, Jiyan Chen, Ning Tan, and Yong Liu
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cancer‐specific mortality ,cardio‐oncology ,coronary artery disease ,proportion ,spectrum ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Globally, coronary artery disease (CAD) and cancer are the leading causes of death. Studies focusing on the proportion and spectrum of cancer mortality among CAD patients are lacking. We aim to characterize the proportion and spectrum of cancer‐specific mortality among patients with CAD. Methods We analyzed 93,797 hospitalized survivors with angiographically documented CAD between 2007 and 2020 (mean age: 62.8 ± 11.1 years, 24.7% female) from Cardiorenal ImprovemeNt II (CIN‐II) cohort. Results During the median follow‐up of 4.8 years (IQR: 2.6–7.5), 13,162 (14.0%) patients died after discharge. A total of 1223/7703 (15.8% of cause‐specific death) CAD patients died of cancer. The three most common types of cancer‐specific death were lung (36.1%), liver (13.3%), and colorectum cancer (12.8%). Furthermore, male (adjusted HR 2.38, 95% CI: 1.99–2.85) and older (≥60 vs.
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- 2023
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7. Impact of stress hyperglycemia ratio on mortality in patients with critical acute myocardial infarction: insight from american MIMIC-IV and the chinese CIN-II study
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Jin Liu, Yang Zhou, Haozhang Huang, Rui Liu, Yu Kang, Tingting Zhu, Jielan Wu, Yuwei Gao, Yuqi Li, Chenyang Wang, Shiqun Chen, Nianjin Xie, Xueyan Zheng, Ruilin Meng, Yong Liu, Ning Tan, and Fei Gao
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Coronary artery disease ,Stress hyperglycemia ratio ,Diabetes ,Mortality ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Among patients with acute coronary syndrome and percutaneous coronary intervention, stress hyperglycemia ratio (SHR) is primarily associated with short-term unfavorable outcomes. However, the relationship between SHR and long-term worsen prognosis in acute myocardial infarction (AMI) patients admitted in intensive care unit (ICU) are not fully investigated, especially in those with different ethnicity. This study aimed to clarify the association of SHR with all-cause mortality in critical AMI patients from American and Chinese cohorts. Methods Overall 4,337 AMI patients with their first ICU admission from the American Medical Information Mart for Intensive Care (MIMIC)-IV database (n = 2,166) and Chinese multicenter registry cohort Cardiorenal ImprovemeNt II (CIN-II, n = 2,171) were included in this study. The patients were divided into 4 groups based on quantiles of SHR in both two cohorts. Results The total mortality was 23.8% (maximum follow-up time: 12.1 years) in American MIMIC-IV and 29.1% (maximum follow-up time: 14.1 years) in Chinese CIN-II. In MIMIC-IV cohort, patients with SHR of quartile 4 had higher risk of 1-year (adjusted hazard radio [aHR] = 1.87; 95% CI: 1.40–2.50) and long-term (aHR = 1.63; 95% CI: 1.27–2.09) all-cause mortality than quartile 2 (as reference). Similar results were observed in CIN-II cohort (1-year mortality: aHR = 1.44; 95%CI: 1.03–2.02; long-term mortality: aHR = 1.32; 95%CI: 1.05–1.66). In both two group, restricted cubic splines indicated a J-shaped correlation between SHR and all-cause mortality. In subgroup analysis, SHR was significantly associated with higher 1-year and long-term all-cause mortality among patients without diabetes in both MIMIC-IV and CIN-II cohort. Conclusion Among critical AMI patients, elevated SHR is significantly associated with and 1-year and long-term all-cause mortality, especially in those without diabetes, and the results are consistently in both American and Chinese cohorts.
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- 2023
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8. Effect of cumulative radiation exposure from Coronary catheterization on lung cancer mortality
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Jin Liu, Shiqun Chen, Yang Zhou, Xueyan Zheng, Ruilin Meng, Ning Tan, and Yong Liu
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Lung cancer mortality ,Coronary catheterization ,Radiation ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Coronary catheterization (CC) procedure inevitably exposes patients with cardiovascular disease (CVD) to radiation, while cumulative radiation exposure may lead to higher risk of cancer. Methods This multi-center, retrospective study was based on the CC procedure in Cardiorenal ImprovemeNt II cohort (CIN-II, NCT05050877) among five regional central tertiary teaching hospitals in China between 2007 and 2020. Patients without known cancer were stratified according to the times they received CC procedure. Baseline information from their last CC procedure was analyzed. Cox regression and Fine-Gray competing risk models were used to assess the relationship between cumulative radiation exposure from CC procedures and cancer-specific, all-cause and cardiovascular mortality. Results Of 136,495 hospitalized survivors without cancer at baseline (mean age: 62.3 ± 11.1 years, 30.9% female), 116,992 patients (85.7%) underwent CC procedure once, 15,184 patients (11.1%) on twice, and 4,319 patients (3.2%) underwent CC procedure more than three times. During the median follow-up of 4.7 years (IQR: 2.5 to 7.4), totally 18,656 patients (13.7%) died after discharge, of which 617 (0.5%) died of lung cancer. Compared with the patients who underwent CC procedure once, the risk of lung cancer mortality increased significantly with the increase of the number of CC procedure (CC 2 times vs. 1 time: HR 1.42, 95% CI 1.13 to 1.78, P
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- 2023
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9. Construction of AQHI based on joint effects of multi-pollutants in 5 provinces of China
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Jinghua GAO, Chunliang ZHOU, Jianxiong HU, Ruilin MENG, Maigeng ZHOU, Zhulin HOU, Yize XIAO, Min YU, Biao HUANG, Xiaojun XU, Tao LIU, Weiwei GONG, Donghui JIN, Mingfang QIN, Peng YIN, Yiqing XU, Guanhao HE, Xianbo WU, Weilin ZENG, and Wenjun MA
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air pollution ,health risk ,air quality health index ,case-crossover design ,Medicine (General) ,R5-920 ,Toxicology. Poisons ,RA1190-1270 - Abstract
BackgroundAir pollution is a major public health concern. Air Quality Health Index (AQHI) is a very important air quality risk communication tool. However, AQHI is usually constructed by single-pollutant model, which has obvious disadvantages.ObjectiveTo construct an AQHI based on the joint effects of multiple air pollutants (J-AQHI), and to provide a scientific tool for health risk warning and risk communication of air pollution.MethodsData on non-accidental deaths in Yunnan, Guangdong, Hunan, Zhejiang, and Jilin provinces from January 1, 2013 to December 31, 2018 were obtained from the corresponding provincial disease surveillance points systems (DSPS), including date of death, age, gender, and cause of death. Daily meteorological (temperature and relative humidity) and air pollution data (SO2, NO2, CO, PM2.5, PM10, and maximum 8 h O3 concentrations) at the same period were respectively derived from China Meteorological Data Sharing Service System and National Urban Air Quality Real-time Publishing Platform. Lasso regression was first applied to select air pollutants, then a time-stratified case-crossover design was applied. Each case was matched to 3 or 4 control days which were selected on the same days of the week in the same calendar month. Then a distributed lag nonlinear model (DLNM) was used to estimate the exposure-response relationship between selected air pollutants and mortality, which was used to construct the AQHI. Finally, AQHI was classified into four levels according to the air pollutant guidance limit values from World Health Organization Global Air Quality Guidelines (AQG 2021), and the excess risks (ERs) were calculated to compare the AQHI based on single-pollutant model and the J-AQHI based on multi-pollutant model.ResultsPM2.5, NO2, SO2, and O3 were selected by Lasso regression to establish DLNM model. The ERs for an interquartile range (IQR) increase and 95% confidence intervals (CI) for PM2.5, NO2, SO2 and O3 were 0.71% (0.34%–1.09%), 2.46% (1.78%–3.15%), 1.25% (0.9%–1.6%), and 0.27% (−0.11%–0.65%) respectively. The distribution of J-AQHI was right-skewed, and it was divided into four levels, with ranges of 0-1 for low risk, 2-3 for moderate risk, 4-5 for high health risk, and ≥6 for severe risk, and the corresponding proportions were 11.25%, 64.61%, 19.33%, and 4.81%, respectively. The ER (95%CI) of mortality risk increased by 3.61% (2.93–4.29) for each IQR increase of the multi-pollutant based J-AQHI , while it was 3.39% (2.68–4.11) for the single-pollutant based AQHI .ConclusionThe J-AQHI generated by multi-pollutant model demonstrates the actual exposure health risk of air pollution in the population and provides new ideas for further improvement of AQHI calculation methods.
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- 2023
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10. Temperature-related mortality in China from specific injury
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Jianxiong Hu, Guanhao He, Ruilin Meng, Weiwei Gong, Zhoupeng Ren, Heng Shi, Ziqiang Lin, Tao Liu, Fangfang Zeng, Peng Yin, Guoxia Bai, Mingfang Qin, Zhulin Hou, Xiaomei Dong, Chunliang Zhou, Zhuoma Pingcuo, Yize Xiao, Min Yu, Biao Huang, Xiaojun Xu, Lifeng Lin, Jianpeng Xiao, Jieming Zhong, Donghui Jin, Qinglong Zhao, Yajie Li, Cangjue Gama, Yiqing Xu, Lingshuang Lv, Weilin Zeng, Xing Li, Liying Luo, Maigeng Zhou, Cunrui Huang, and Wenjun Ma
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Science - Abstract
Injury poses heavy burden on public health, but little evidence on the potential role of climate change on injury exists. Here, the authors collect data during 2013-2019 in six provinces of China to estimate the associations between temperature and injury mortality, and to project future mortality burden attributable to temperature change driven by climate change.
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- 2023
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11. The Combined Effects of Short-Term Exposure to Multiple Meteorological Factors on Unintentional Drowning Mortality: Large Case-Crossover Study
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Yingyin Liu, Xiaomei Dong, Zhixing Li, Sui Zhu, Ziqiang Lin, Guanhao He, Weiwei Gong, Jianxiong Hu, Zhulin Hou, Ruilin Meng, Chunliang Zhou, Min Yu, Biao Huang, Lifeng Lin, Jianpeng Xiao, Jieming Zhong, Donghui Jin, Yiqing Xu, Lingshuang Lv, Cunrui Huang, Tao Liu, and Wenjun Ma
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Public aspects of medicine ,RA1-1270 - Abstract
BackgroundDrowning is a serious public health problem worldwide. Previous epidemiological studies on the association between meteorological factors and drowning mainly focused on individual weather factors, and the combined effect of mixed exposure to multiple meteorological factors on drowning is unclear. ObjectiveWe aimed to investigate the combined effects of multiple meteorological factors on unintentional drowning mortality in China and to identify the important meteorological factors contributing to drowning mortality. MethodsUnintentional drowning death data (based on International Classification of Diseases, 10th Edition, codes W65-74) from January 1, 2013, to December 31, 2018, were collected from the Disease Surveillance Points System for Guangdong, Hunan, Zhejiang, Yunnan, and Jilin Provinces, China. Daily meteorological data, including daily mean temperature, relative humidity, sunlight duration, and rainfall in the same period were obtained from the Chinese Academy of Meteorological Science Data Center. We constructed a time-stratified case-crossover design and applied a generalized additive model to examine the effect of individual weather factors on drowning mortality, and then used quantile g-computation to estimate the joint effect of the mixed exposure to meteorological factors. ResultsA total of 46,179 drowning deaths were reported in the 5 provinces in China from 2013 to 2018. In an effect analysis of individual exposure, we observed a positive effect for sunlight duration, a negative effect for relative humidity, and U-shaped associations for temperature and rainfall with drowning mortality. In a joint effect analysis of the above 4 meteorological factors, a 2.99% (95% CI 0.26%-5.80%) increase in drowning mortality was observed per quartile rise in exposure mixture. For the total population, sunlight duration was the most important weather factor for drowning mortality, with a 93.1% positive contribution to the overall effects, while rainfall was mainly a negative factor for drowning deaths (90.5%) and temperature and relative humidity contributed 6.9% and –9.5% to the overall effects, respectively. ConclusionsThis study found that mixed exposure to temperature, relative humidity, sunlight duration, and rainfall was positively associated with drowning mortality and that sunlight duration, rather than temperature, may be the most important meteorological factor for drowning mortality. These findings imply that it is necessary to incorporate sunshine hours and temperature into early warning systems for drowning prevention in the future.
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- 2023
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12. Mortality burden based on the associations of ambient PM2.5 with cause-specific mortality in China: Evidence from a death-spectrum wide association study (DWAS)
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Tao Liu, Weiwei Gong, Chunliang Zhou, Guoxia Bai, Ruilin Meng, Biao Huang, Haoming Zhang, Yanjun Xu, Ruying Hu, Zhulin Hou, Yize Xiao, Junhua Li, Xiaojun Xu, Donghui Jin, Mingfang Qin, Qinglong Zhao, Yiqing Xu, Jianxiong Hu, Jianpeng Xiao, Guanghao He, Zuhua Rong, Fangfang Zeng, Pan Yang, Dan Liu, Lixia Yuan, Ganxiang Cao, Zhiqing Chen, Siwen Yu, Shangfeng Yang, Cunrui Huang, Yaodong Du, Min Yu, Lifeng Lin, Xiaofeng Liang, and Wenjun Ma
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Air pollution ,Cause-specific association ,Mortality burden ,Environmental pollution ,TD172-193.5 ,Environmental sciences ,GE1-350 - Abstract
Although studies have estimated the associations of PM2.5 with total mortality or cardiopulmonary mortality, few have comprehensively examined cause-specific mortality risk and burden caused by ambient PM2.5. Thus, this study investigated the association of short-term exposure to PM2.5 with cause-specific mortality using a death-spectrum wide association study (DWAS). Individual information of 5,450,764 deaths during 2013–2018 were collected from six provinces in China. Daily PM2.5 concentration in the case and control days were estimated by a random forest model. A time-stratified case-crossover study design was applied to estimate the associations (access risk, ER) of PM2.5 with cause-specific mortality, which was then used to calculate the population-attributable fraction (PAF) of mortality and the corresponding mortality burden caused by PM2.5. Each 10 μg/m3 increase in PM2.5 concentration (lag03) was associated with a 0.80 % [95 % confidence interval (CI): 0.73 %, 0.86 %] rise in total mortality. We found greater mortality effect at PM2.5 concentrations
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- 2023
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13. The impact of mortality underreporting on the association of ambient temperature and PM10 with mortality risk in time series study
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Ziqiang Lin, Wayne R. Lawrence, Weiwei Gong, Lifeng Lin, Jianxiong Hu, Sui Zhu, Ruilin Meng, Guanhao He, Xiaojun Xu, Tao Liu, Jieming Zhong, Min Yu, Karin Reinhold, and Wenjun Ma
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Underreporting ,Mortality ,Temperature ,Underreporting at random ,PM10 ,Science (General) ,Q1-390 ,Social sciences (General) ,H1-99 - Abstract
Properly analyzing and reporting data remains a challenging task in epidemiologic research, as underreporting of data is often overlooked. The evaluation on the effect of underreporting remains understudied. In this study, we examined the effect of different scenarios of mortality underreporting on the relationship between PM10, temperature, and mortality. Mortality data, PM10, and temperature data in seven cities were obtained from Provincial Center for Disease Control and Prevention (CDC), China Meteorological Data Sharing Service System, and China National Environmental Monitoring Center, respectively. A time-series design with a distributed lag nonlinear model (DLNM) was used to examine the effects of five mortality underreporting scenarios: 1) Random underreporting of mortality; 2) Underreporting is monotonically increasing (MI) or monotonically decreasing (MD); 3) Underreporting due to holiday and weekends; 4) Underreporting occurs before the 20th day of each month, and these underreporting will be added after the 20th day of the month; and 5) Underreporting due to holiday, weekends, MI, and MD. We observed that underreporting at random (UAR) scenario had little effect on the association between PM10, temperature, and daily mortality. However, other four underreporting not at random (UNAR) scenarios mentioned above had varying degrees of influence on the association between PM10, temperature, and daily mortality. Additionally, in addition to imputation under UAR, the variation of minimum mortality temperature (MMT) and attributable fraction (AF) of mortality attributed to temperature in the same imputation scenarios is inconsistent in different cities. Finally, we observed that the pooled excess risk (ER) below MMT was negatively associated with mortality and the pooled ER above MMT was positively associated with mortality. This study showed that UNAR impacted the association between PM10, temperature, and mortality, and potential underreporting should be dealt with before analyzing data to avoid drawing invalid conclusions.
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- 2023
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14. Relationship between heatwave and years of life lost associated with stroke in Guangdong Province: Based on Bayesian spatio-temporal model
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Lixia YUAN, Ruilin MENG, Jiali LI, Lifeng LIN, Xiaojun XU, Jianpeng XIAO, Guanhao HE, Jianxiong HU, Zuhua RONG, Wenjun MA, and Tao LIU
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stroke ,heatwave ,bayesian spatio-temporal model ,exposure-response relationship ,modifier ,Medicine (General) ,R5-920 ,Toxicology. Poisons ,RA1190-1270 - Abstract
BackgroundStroke has become a main cause of death in China. With global warming, the studies on temperature and stroke have attracted much attention.ObjectiveTo analyze he relationships between heatwave and the years of life lost (YLL) by different subtypes of stroke by controlling temporal and spatial effects with Bayesian spatio-temporal model, and to study the modifiers of the health effect of heatwave.MethodsThe daily information of stroke deaths, meteorological data, and air pollutant data in 40 districts and counties of Guangdong Province were collected during the warm seasons (from May to October) in the years from 2014 to 2017. The individual YLL was first calculated by matching age and gender according to the life table, and then the daily YLL rate (person-years/100 000 people) was obtained by summarizing the daily YLL and correcting it with the population of each district or county. Bayesian spatio-temporal model was used to fit a proposed exposure-response relationship between heatwave and the YLL rates of different subtypes of stroke. Finally, stratified analyses were conducted by age (
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- 2022
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15. Effects of ambient temperature on metabolic syndrome and pathway analysis
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Jie HU, Jiali LUO, Zihui CHEN, Siqi CHEN, Guiyuan JI, Xiaojun XU, Ruilin MENG, Jianpeng XIAO, Guanhao HE, Haorong MENG, Jianxiong HU, Weilin ZENG, Xing LI, Lingchuan GUO, and Wenjun MA
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ambient temperature ,metabolic syndrome ,path analysis ,exposure-effect relationship ,generalized additive model ,Medicine (General) ,R5-920 ,Toxicology. Poisons ,RA1190-1270 - Abstract
BackgroundIn recent years, the incidence of metabolic syndrome (MS) is increasing significantly in China. Some studies have found that temperature is related to single metabolic index, but there is a lack of research on associated mechanism and identifying path of the influence of temperature on MS.ObjectiveBased on the data of Guangdong Province, to investigate the effect of temperature on MS and its pathway.MethodsA total of 8524 residents were enrolled by multi-stage random sampling from October 2015 to January 2016 in Guangdong. Basic characteristics, behavioral characteristics, health status, and physical activity level were obtained through questionnaires and physical examinations, and meteorological data were obtained from meteorological monitoring sites. We matched individual data both with the temperature data of the physical examination day and of a lag of 14 d. A generalized additive model was used to explore the exposure-effect relationship between temperature and MS and its indexes, calculate effect values, and explore the effects of single-day lag temperature. Based on the literature and the results of generalized additive model analysis, a path analysis was conducted to explore the pathways of temperature influencing MS.ResultsThe association between daily average temperature on the current day or lag 14 day and MS risk was not statistically significant. When daily average temperature increased by 1 ℃, the change values of fasting blood-glucose (FBG), systolic blood pressure (SBP), diastolic blood pressure (DBP), and high density lipoprotein cholesterol (HDL-C) were −0.033 (95%CI: −0.040-−0.026) mmol·L−1, −0.662 (95%CI: −0.741-−0.583) mmHg, −0.277 (95%CI: −0.323-−0.230) mmHg, and −0.005 (95%CI: −0.007-−0.004) mmol·L−1 respectively. The effects of average daily temperature on FBG, blood pressure, HDL-C, and waist circumference lasted until lag 14 day. The effects of daily average temperature on SBP and DBP were the largest on the current day. Daily average temperature of current day had direct and indirect effects on FBG and SBP. Temperature had an indirect effect on TG, and the intermediate variables were waist circumference and FBG, with an indirect effect value of −0.011 (95%CI: −0.020-−0.002). The indirect effects of daily average temperature on SBP, FBG, and TG were weak.ConclusionThere is no significant correlation between temperature and risk of MS, and daily average temperature of current day could significantly affected blood pressure and FBG with a lag effect. Daily average temperature of current day has indirect effects on FBG and TG.
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- 2022
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16. Association of compound hot extreme with blood pressure in Guangdong province
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Zhixing LI, Shunwei LIN, Xiaojun XU, Ruilin MENG, Guanhao HE, Jianxiong HU, He ZHOU, Weilin ZENG, Xing LI, Jianpeng XIAO, Tao LIU, and Wenjun MA
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blood pressure ,compound hot extreme ,distributed lag non-linear model ,extreme climate ,Medicine (General) ,R5-920 ,Toxicology. Poisons ,RA1190-1270 - Abstract
BackgroundIt is projected that the frequency, density, and duration of compound hot extreme may increase in the 21st century in the context of global warming.ObjectiveTo explore the association between compound hot extreme and blood pressure, and identify sensitive populations.MethodsThis was a cross-sectional study. The study subjects were from six Guangdong Province Chronic Disease and Nutrition Surveys during 2002 through 2015. A questionnaire was administered to the participants with questions about demographic information, drinking and smoking status, and measurements on their height, weight, and blood pressure were also collected. We chose the data of May, September, and October to explore the association between compound hot extreme and blood pressure. Compound hot extreme means a hot day with a proceeding hot night. Daily meteorological data were obtained from China Meteorological Data Service Centre. We employed inverse distance weighting to interpolate the temperature and relative humidity values for each participant. A distributed lag non-linear model was used to estimate the association between compound hot extreme and blood pressure. Stratified analyses by sex, age, area, body mass index (BMI), smoking status, and drinking status were also performed to identify sensitive populations. A sensitivity analysis was conducted by adjusting the degrees of freedom for lag spline and removing relative humidity.ResultA total of 10967 participants without history of hypertension were included in this study. The average systolic blood pressure (SBP) was 120.8 mmHg and the average diastolic blood pressure (DBP) was 74.5 mmHg. The proportion of participants who experienced hot day, hot night, or compound hot extreme were 9.34%, 17.95% and 2.90%, respectively. Compared to hot day, hot night and compound hot extreme were related with decreased blood pressure, and the effect of compound hot extreme was stronger: the changes and 95%CI for SBP was −6.2 (−10.3-−2.1) mmHg, and for DBP was −2.7 (−5.2-−0.2) mmHg. Compound hot extreme induced decreased SBP among male, population ≥ 65 years, and those whose BMI < 24 kg·m-2, and their ORs (95%CIs) were −6.2 (−10.7-−1.6). −19.1 (−33.0-−5.1), and −6.7 (−11.8~−1.6) mmHg, respectively, and also decreased DBP among population ≥ 65 years, and its OR (95%CI) was −8.4 (−15.6-−1.1) mmHg. During compound hot extremes, participants living in rural areas showed decreased SBP and DBP, and the ORs (95%CIs) were −10.5 (−16.6-−4.5) and −4.4 (−7.7-−1.1) mmHg respectively, while those living in urban areas showed increased SBP, and the OR (95%CI) was 9.7 (2.9-16.5) mmHg. A significant decrease in blood pressure [OR (95%CI)] was also found in non-smokers [DBP, −3.7 (−6.6-−0.8) mmHg] and non-drinkers [SBP, −4.8 (−9.4-−0.2) mmHg; DBP, −3.4 (−6.0-−0.9) mmHg].ConclusionCompound hot extreme is negatively associated with SBP, and being male, aged 65 years and over, and having BMI < 24 kg·m−2 may be more sensitive to compound hot extreme.
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- 2022
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17. The joint and interaction effect of high temperature and humidity on mortality in China
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Wen Fang, Zhixing Li, Jinghua Gao, Ruilin Meng, Guanhao He, Zhulin Hou, Sui Zhu, Maigeng Zhou, Chunliang Zhou, Yize Xiao, Min Yu, Biao Huang, Xiaojun Xu, Lifeng Lin, Jianpeng Xiao, Donghui Jin, Mingfang Qin, Peng Yin, Yiqing Xu, Jianxiong Hu, Tao Liu, Cunrui Huang, and Wenjun Ma
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Temperature ,Relative humidity ,Interaction effect ,Mortality ,Environmental sciences ,GE1-350 - Abstract
Background: Although many studies have reported the mortality effect of temperature, there were few studies on the mortality risk of humidity, let alone the joint effect of temperature and humidity. This study aimed to investigate the joint and interaction effect of high temperature and relative humidity on mortality in China, which will deepen understanding the health risk of mixture climate exposure. Methods: The mortality and meteorological data were collected from 353 locations in China (2013–2017 in Jilin, Hunan, Guangdong and Yunnan provinces, 2009–2017 in Zhejiang province, and 2006–2011 in other Provinces). We defined location-specific daily mean temperature ≥ 75th percentile of distribution as high temperature, while minimum mortality relative humidity as the threshold of high relative humidity. A time-series model with a distributed lag non-linear model was first employed to estimate the location-specific associations between humid-hot events and mortality, then we conducted meta-analysis to pool the mortality effect of humid-hot events. Finally, an additive interaction model was used to examine the interactive effect between high temperature and relative humidity. Results: The excess rate (ER) of non-accidental mortality attributed to dry-hot events was 10.18% (95% confidence interval (CI): 8.93%, 11.45%), which was higher than that of wet-hot events (ER = 3.21%, 95% CI: 0.59%, 5.89%). The attributable fraction (AF) of mortality attributed to dry-hot events was 10.00% (95% CI: 9.50%, 10.72%) with higher burden for females, older people, central China, cardiovascular diseases and urban city. While for wet-hot events, AF was much lower (3.31%, 95% CI: 2.60%, 4.30%). We also found that high temperature and low relative humidity had synergistic additive interaction on mortality risk. Conclusion: Dry-hot events may have a higher risk of mortality than wet-hot events, and the joint effect of high temperature and low relative humidity may be greater than the sum of their individual effects.
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- 2023
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18. The Spring Festival Is Associated With Increased Mortality Risk in China: A Study Based on 285 Chinese Locations
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Guanhao He, Min Cai, Ruilin Meng, Jianxiong Hu, Ke Peng, Zhulin Hou, Chunliang Zhou, Xiaojun Xu, Yize Xiao, Min Yu, Biao Huang, Lifeng Lin, Tao Liu, Jianpeng Xiao, Weiwei Gong, Ruying Hu, Junhua Li, Donghui Jin, Mingfang Qin, Qinglong Zhao, Yiqing Xu, Weilin Zeng, Xing Li, Cunrui Huang, Lei Si, Xingfen Yang, and Wenjun Ma
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Spring Festival ,mortality risk ,China ,vulnerable population ,attributable fraction (AF) ,Medicine (General) ,R5-920 - Abstract
BackgroundThe Spring Festival is one of the most important traditional festivals in China. This study aimed to estimate the mortality risk attributable to the Spring Festival.MethodsBetween 2013 and 2017, daily meteorological, air pollution, and mortality data were collected from 285 locations in China. The Spring Festival was divided into three periods: pre-Spring Festival (16 days before Lunar New Year's Eve), mid-Spring Festival (16 days from Lunar New Year's Eve to Lantern Festival), and post-Spring Festival (16 days after Lantern Festival). The mortality risk attributed to the Spring Festival in each location was first evaluated using a distributed lag nonlinear model (DLNM), and then it was pooled using a meta-analysis model.ResultsWe observed a dip/rise mortality pattern during the Spring Festival. Pre-Spring Festival was significantly associated with decreased mortality risk (ER: −1.58%, 95%CI: −3.09% to −0.05%), and mid-Spring Festival was unrelated to mortality risks, while post-Spring Festival was significantly associated with increased mortality risk (ER: 3.63%, 95%CI: 2.15–5.12%). Overall, a 48-day Spring Festival period was associated with a 2.11% (95%CI: 0.91–3.33%) increased mortality. We also found that the elderly aged over 64 years old, women, people with cardiovascular disease (CVD), and people living in urban areas were more vulnerable to the Spring Festival.ConclusionOur study found that the Spring Festival significantly increased the mortality risk in China. These findings suggest that it is necessary to develop clinical and public health policies to alleviate the mortality burden associated with the Spring Festival.
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- 2022
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19. Non-Fatal Drowning Risk Prediction Based on Stacking Ensemble Algorithm
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Xinshan Xie, Zhixing Li, Haofeng Xu, Dandan Peng, Lihua Yin, Ruilin Meng, Wei Wu, Wenjun Ma, and Qingsong Chen
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drowning ,machine learning ,stacking ensemble ,risk-factors ,prediction ,Pediatrics ,RJ1-570 - Abstract
Drowning is a major public health problem and a leading cause of death in children living in developing countries. We seek better machine learning (ML) algorithms to provide a novel risk-assessment insight on non-fatal drowning prediction. The data on non-fatal drowning were collected in Qingyuan city, Guangdong Province, China. We developed four ML models to predict the non-fatal drowning risk, including a logistic regression model (LR), random forest model (RF), support vector machine model (SVM), and stacking-based model, on three primary learners (LR, RF, SVM). The area under the curve (AUC), F1 value, accuracy, sensitivity, and specificity were calculated to evaluate the predictive ability of the different learning algorithms. This study included a total of 8390 children. Of those, 12.07% (1013) had experienced non-fatal drowning. We found the following risk factors are closely associated with the risk of non-fatal drowning: the frequency of swimming in open water, distance between the school and the surrounding open waters, swimming skills, personality (introvert) and relationality with family members. Compared to the other three base models, the stacking generalization model achieved a superior performance in the non-fatal drowning dataset (AUC = 0.741, sensitivity = 0.625, F1 value = 0.359, accuracy = 0.739 and specificity = 0.754). This study indicates that applying stacking ensemble algorithms in the non-fatal drowning dataset may outperform other ML models.
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- 2022
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20. An exploratory model for the non-fatal drowning risks in children in Guangdong, China
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Haofeng Xu, Xuhao Zhu, Zhishan Zhou, Yanjun Xu, Yongjian Zhu, Lifeng Lin, Jinying Huang, and Ruilin Meng
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Drowning ,Children ,Risk factors ,Logistic regression model ,Prediction ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Drowning is a leading cause of accidental death in children under 14 years of age in Guangdong, China. We developed a statistical model to classify the risk of drowning among children based on the risk factors. Methods A multiple-stage cluster random sampling was employed to select the students in Grades 3 to 9 in two townships in Qingyuan, Guangdong. Questionnaire was a self-reported measure consisting of general information, knowledge, attitudes and activities. A univariate logistic regression model was used to preliminarily select the independent variables at a P value of 0.1 for multivariable model. Three-quarters of the participants were randomly selected as a training sample to establish the model, and the remaining were treated as a testing sample to validate the model. Results A total of 8390 children were included in this study, about 12.18% (1013) experienced drowning during the past one year. In the univariate logistic regression model, introvert personality, unclear distributions of water areas on the way to school, and bad relationships with their classmates and families were positively associated with drowning. However, females, older age and lower swimming skills were negatively associated with drowning. After employing the prediction model with these factors to estimate drowning risk of the students in the testing samples, the results of Hosmer-Lemeshow tests showed non-significant differences between the predictive results and actual risk (χ2 = 5.97, P = 0.65). Conclusions Male, younger children, higher swimming skills, bad relationship with their classmates and families, introvert personality and unclear distributions of water areas on the way to school were important risk factors of non-fatal drowning among children. The prediction model based on these variables has an acceptable predictive ability.
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- 2019
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21. Epidemiological characteristics of injury mortality in Guangdong Province, China, 2015
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Ruilin Meng, Xiaojun Xu, Yanjun Xu, Chao Luo, Haofeng Xu, Ye Wang, Xiuling Song, Liang Xia, Ni Xiao, Shaoen Zhou, and Lifeng Lin
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Mortality ,Injury ,Prevention ,Road-traffic accident ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background As the fourth leading cause of death, injury is an important public health concern in Guangdong Province, China. The epidemiological characteristics of injury mortality is changing along with the social development. This study described the epidemiological characteristics of injury mortality in Guangdong Province by analyzing the death surveillance data in a few areas in Guangdong Province in 2015. Methods Using the mortality data from the Disease Surveillance Points (DSP) system, injury deaths were classified according to the International Classification of Disease-10th Revision (ICD-10). The data were stratified by areas (urban/rural), gender, age groups, injury types, and then overall and type-specific injury mortality rates were estimated for the whole Guangdong Province, China. Results We estimated that about 38,200 individuals died from injury in Guangdong Province in 2015, producing a mortality rate of 43.11/100,000. The overall age-standardized injury mortality in men was higher in rural areas compared with urban areas (41.29/100,000 versus 24.89/100,000). In terms of injury intent, unintentional injuries were the commonnest injury type, which accounted for 83.93% of the overall injury deaths, however, the deaths caused by suicide should not be ignored, which occupied 12.67% of the total injury deaths. In terms of injury cause type, falls, road-traffic accidents, suicide, drowning, and accidental poisoning were the top five leading types of injury deaths. Conclusions In Guangdong Province, injury is an important cause of death. Road-traffic accidents, falls, suicide, drowning, and accidental poisoning should be the priorities of intervention. Moreover, in rural areas, the men were the most targeted subpopulation of the prevention activities.
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- 2019
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22. Enhancing Both TM- and TE-Polarized Light Extraction Efficiency of AlGaN-Based Deep Ultraviolet Light-Emitting Diode via Air Cavity Extractor With Vertical Sidewall
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Yonghui Zhang, Yuxin Zheng, Ruilin Meng, Ce Sun, Kangkai Tian, Chong Geng, Zi-Hui Zhang, Guoxu Liu, and Wengang Bi
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Light-emitting diodes ,AlGaN ,light extraction efficiency. ,Applied optics. Photonics ,TA1501-1820 ,Optics. Light ,QC350-467 - Abstract
In this work, we investigate the effect of sidewall angle, height and space of an air cavity extractor (AC-Extractor) on the polarization-dependent light extraction efficiency (LEE) for AlGaN-based deep-ultraviolet light-emitting diodes (DUV LEDs) using three-dimensional finite difference time-domain method. Compared to the reported inclined sidewall metal reflector (SM-Reflector), DUV LED with AC-Extractor shows better light extraction at any height and inclined angle due to different light extraction mechanisms. The light in SM-Reflector DUV LED is extracted mainly through mirror reflection. However, total internal reflection from the sidewall dominants the contribution to LEE for the AC-Extractor with smaller inclined angle such that the space has little impact, while Fresnel scattering is more important for the AC-Extractor with larger inclined angle and that the additional out-light channel as well as the space play a critical role in enhancing the LEE. And the analysis is further developed into a three-escape-cones analytic model theory. In particular, the AC-Extractor with vertical sidewall is more beneficial to enhance the LEE of DUV LED than that with inclined sidewall, which can be rationally explained based on the three-escape-cones analytic model.
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- 2018
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23. Effects of Inclined Sidewall Structure With Bottom Metal Air Cavity on the Light Extraction Efficiency for AlGaN-Based Deep Ultraviolet Light-Emitting Diodes
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Yonghui Zhang, Ruilin Meng, Zi-Hui Zhang, Qiang Shi, Luping Li, Guoxu Liu, and Wengang Bi
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Light-emitting diodes ,AlGaN ,light extraction efficiency. ,Applied optics. Photonics ,TA1501-1820 ,Optics. Light ,QC350-467 - Abstract
An inclined sidewall scattering structure with air cavity characterized by a metal bottom and flat parallel top (Bottom_metal) is proposed to enhance the light extraction efficiency (LEE) for AlGaN-based deep ultraviolet light-emitting diodes (DUV LEDs). Compared to the reported sidewall metal inclined sidewall (Sidewall_metal) structure, the Bottom_metal structure can greatly enhance the LEE of DUV LEDs based on three-dimensional finite difference time domain simulations. Further analysis indicates that the existence of the air cavity promotes the Bottom_metal DUV LEDs to mainly utilize the total internal reflection and the Fresnel scattering to scatter the light into the escape cone, which avoids the light absorption from the sidewall metal mirror in the Sidewall_metal structure. Moreover, the unique air cavity having a bottom metal also enhances the scattering ability of the Bottom_metal DUV LEDs because any light within the cavity directing downward will be reflected back, and the parallel top interface of air cavity/AlGaN functions as additional out-light planes not limited by total internal reflection.
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- 2017
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24. Epitaxy of III-Nitrides on β-Ga2O3 and Its Vertical Structure LEDs
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Weijiang Li, Xiang Zhang, Ruilin Meng, Jianchang Yan, Junxi Wang, Jinmin Li, and Tongbo Wei
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β-Ga2O3 ,III-Nitrides ,monoclinic ,hexagonal arrangement ,high-power ,current distribution ,vertical structure LED ,Mechanical engineering and machinery ,TJ1-1570 - Abstract
β-Ga2O3, characterized with high n-type conductivity, little lattice mismatch with III-Nitrides, high transparency (>80%) in blue, and UVA (400–320 nm) as well as UVB (320–280 nm) regions, has great potential as the substrate for vertical structure blue and especially ultra violet LEDs (light emitting diodes). Large efforts have been made to improve the quality of III-Nitrides epilayers on β-Ga2O3. Furthermore, the fabrication of vertical blue LEDs has been preliminarily realized with the best result that output power reaches to 4.82 W (under a current of 10 A) and internal quantum efficiency (IQE) exceeds 78% by different groups, respectively, while there is nearly no demonstration of UV-LEDs on β-Ga2O3. In this review, with the perspective from materials to devices, we first describe the basic properties, growth method, as well as doping of β-Ga2O3, then introduce in detail the progress in growth of GaN on (1 0 0) and (−2 0 1) β-Ga2O3, followed by the epitaxy of AlGaN on gallium oxide. Finally, the advances in fabrication and performance of vertical structure LED (VLED) are presented.
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- 2019
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25. Effect of integrated intervention to prevent child drowning in rural areas of Guangdong, China: a cluster randomized controlled trial
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Ruilin Meng, Haofeng Xu, Mingqu Zhang, Pengpeng Ye, Zhishan Zhou, Xuhao Zhu, Xingru Li, and Lifeng Lin
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Infectious Diseases ,Pediatrics, Perinatology and Child Health - Abstract
Background Drowning is the leading cause of death for children under the age of 15 years in Guangdong Province, China. This serious public health issue also exists in low- and middle-income countries (LMICs), which have few value-integrated intervention programs. The current study presents an integrated intervention project that aims to explore an effective pattern of prevention for child drowning in rural areas and feasibility to perform in other LMICs. Methods We conducted a cluster randomized controlled trial by comparing the incidence of non-fatal drowning among children in two groups in rural areas of southern China. We recruited the participants in two phases and reached a total of 10 687 students from 23 schools at two towns in Guangdong Province, China. At the first and second phases, 8966 and 1721 students were recruited, respectively. Results The final evaluation questionnaires were collected after 18 months of integrated intervention, where we obtained 9791 data from Grades 3–9. The incidence of non-fatal drowning between the intervention and control groups after intervention did not differ significantly from the baseline according to the total number of students, male students, female students and Grades 6–9 [0.81; 95% confidence interval (CI): [0.66, 1.00]; p = 0.05, 1.17; 95% CI: [0.90, 1.51]; p = 0.25, 1.40; 95% CI: [0.97, 2.02]; p = 0.07 and 0.97; 95% CI: [0.70, 1.34]; p = 0.86], except for Grades 3–5 (1.36; 95% CI: [1.02, 1.82]; p = 0.037). The study observed a significantly positive benefit of awareness and risk behaviours of non-fatal drowning between the intervention and control groups (0.27, 95% CI: [0.21, 0.33]; p = 0.00, −0.16; 95% CI: [−0.24, −0.08]; p = 0.00). Conclusions The integrated intervention exerted a significant impact on the prevention and management of child non-fatal drowning, especially in rural areas.
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- 2023
26. The association of ambient temperature variability with blood pressure in southern China
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Muyun Li, Jiali Luo, Jianxiong Hu, Ruilin Meng, Xiaojun Xu, Guanhao He, Xing Li, Tao Liu, Jianpeng Xiao, Weilin Zeng, Yuqin Wang, and Wenjun Ma
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Advanced and Specialized Nursing ,Adult ,China ,Cross-Sectional Studies ,Adolescent ,Hypertension ,Internal Medicine ,Temperature ,Humans ,Blood Pressure ,General Medicine ,Assessment and Diagnosis ,Cardiology and Cardiovascular Medicine - Abstract
Numerous studies have shown a positive relationship between temperature variability and mortality, but few studies have investigated the effect of temperature variability on blood pressure (BP). We aimed to estimate the effect of temperature variability on BP in Guangdong Province, southern China.Data on meteorological factors were obtained from the Guangdong Meteorological Center, and BP was collected from a series of cross-sectional surveys conducted in Guangdong Province, China, from 2004 to 2015. There were 38 088 participants aged 18 years and over. A generalized additive model was used to estimate the association between temperature variability and BP after adjusting for confounding variables.Our study found a significant positive association between temperature variability and SBP, and this effect increased with the increment of exposure days in total population. The highest estimate was for temperature variability at 7 days lag (TV 0-7 ) with a 0.497 (95% confidence interval, 0.335-0.660) mmHg rise of SBP for each 1°C increase of TV 0-7 . The effects of TV 0-1 and TV 0-2 on SBP were higher for hypertensives than that for normotensives, and in warm season higher than that in cold season. However, we did not observe statistical significance between temperature variability and DBP.There was a positive association between temperature variability and SBP in Guangdong Province, which should be considered in clinical management and epidemiological survey of hypertension.
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- 2023
27. The joint and interaction effect of high temperature and humidity on mortality in China
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Wen Fang, Zhixing Li, Jinghua Gao, Ruilin Meng, Guanhao He, Zhulin Hou, Sui Zhu, Maigeng Zhou, Chunliang Zhou, Yize Xiao, Min Yu, Biao Huang, Xiaojun Xu, Lifeng Lin, Jianpeng Xiao, Donghui Jin, Mingfang Qin, Peng Yin, Yiqing Xu, Jianxiong Hu, Tao Liu, Cunrui Huang, and Wenjun Ma
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General Environmental Science - Abstract
Although many studies have reported the mortality effect of temperature, there were few studies on the mortality risk of humidity, let alone the joint effect of temperature and humidity. This study aimed to investigate the joint and interaction effect of high temperature and relative humidity on mortality in China, which will deepen understanding the health risk of mixture climate exposure.The mortality and meteorological data were collected from 353 locations in China (2013-2017 in Jilin, Hunan, Guangdong and Yunnan provinces, 2009-2017 in Zhejiang province, and 2006-2011 in other Provinces). We defined location-specific daily mean temperature ≥ 75th percentile of distribution as high temperature, while minimum mortality relative humidity as the threshold of high relative humidity. A time-series model with a distributed lag non-linear model was first employed to estimate the location-specific associations between humid-hot events and mortality, then we conducted meta-analysis to pool the mortality effect of humid-hot events. Finally, an additive interaction model was used to examine the interactive effect between high temperature and relative humidity.The excess rate (ER) of non-accidental mortality attributed to dry-hot events was 10.18% (95% confidence interval (CI): 8.93%, 11.45%), which was higher than that of wet-hot events (ER = 3.21%, 95% CI: 0.59%, 5.89%). The attributable fraction (AF) of mortality attributed to dry-hot events was 10.00% (95% CI: 9.50%, 10.72%) with higher burden for females, older people, central China, cardiovascular diseases and urban city. While for wet-hot events, AF was much lower (3.31%, 95% CI: 2.60%, 4.30%). We also found that high temperature and low relative humidity had synergistic additive interaction on mortality risk.Dry-hot events may have a higher risk of mortality than wet-hot events, and the joint effect of high temperature and low relative humidity may be greater than the sum of their individual effects.
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- 2022
28. Factors associated with the uptake of national essential public health service package for hypertension and type-2 diabetes management in China's primary health care system: a mixed-methods study
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Shangzhi Xiong, Wei Jiang, Ruilin Meng, Chi Hu, Hui Liao, Yongchen Wang, Chang Cai, Xinyi Zhang, Pengpeng Ye, Yanqiuzi Ma, Tingzhuo Liu, Dandan Peng, Jiajuan Yang, Li Gong, Qiujun Wang, David Peiris, Limin Mao, and Maoyi Tian
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Psychiatry and Mental health ,Infectious Diseases ,Health Policy ,Pediatrics, Perinatology and Child Health ,Public Health, Environmental and Occupational Health ,Internal Medicine ,Obstetrics and Gynecology ,Geriatrics and Gerontology - Published
- 2023
29. Effects of occupational exposure to dust, gas, vapor and fumes on chronic bronchitis and lung function impairment
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Xueyan Zheng, Yijin Zheng, Tingting Liao, Yanjun Xu, Li Liu, Ye Wang, Ni Xiao, Chuan Li, Ruilin Meng, Weijie Guan, Lifeng Lin, and Zhaoxuan He
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respiratory tract diseases - Abstract
Objectives: We sought to investigate the effects of occupational exposure to vapors, gases, dust and fumes (VGDF) on chronic bronchitis and lung function impairment. Methods: We conducted chronic obstructive pulmonary disease surveillance in six cities of south China between 2014 and 2019. We recorded the diagnosis of chronic bronchitis, respiratory symptoms, occupational exposure to VGDF and other covariates by using a structured questionnaire. Logistic regression and multivariate linear regression model were adopted for analysis. Results: A total of 7418 and 5249 participants were included. Cough (OR: 1.60, 95%CI: 1.22 to 2.08) and phlegm (OR: 1.49, 95%CI: 1.19 to 1.85) correlated significantly with the exposure to dust. There was an increased risk of cough (OR: 1.53, 95%CI: 1.11 to 2.07) for occupational exposure to gas/vapor/fume. Dual exposure to dust and gas/vapor/fume was associated with a significantly increased risk of chronic bronchitis (OR: 1.74, 95%CI: 1.20 to 2.52), as well as cough (OR: 1.43, 95%CI: 1.15 to 1.79) and phlegm (OR: 1.49, 95%CI: 1.24 to 1.79). Gas/vapor/fume was associated with the reduced ratio of forced expiratory volume in one second and forced vital capacity (FEV1/FVC) (β: -1.05, 95%CI: -1.85 to -0.26) and maximal mid-expiratory flow(MMEF) (β: -0.15, 95%CI: -0.23 to -0.07). Dual exposure to dust and gas/vapor/fume was significantly associated with decreased FEV1/FVC (β: -0.74, 95%CI: -1.28 to -0.20) and MMEF (β: -0.06, 95%CI: -0.12 to -0.01) . Results of sensitivity analysis did not materially change. Conclusions: VGDF exposure was associated with chronic bronchitis, respiratory symptoms and impaired lung function, suggesting that VGDF contribute to the pathogenesis and progression of COPD.
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- 2022
30. Projected Injury Mortality Burden Attributable to Compound Hot Extremes Increased Significantly in the Future in China
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Liying Luo, Fangfang Zeng, Guoxia Bai, Weiwei Gong, Jianxiong Hu, Guanhao He, Heng Shi, Ziqiang Lin, Tao Liu, Peng Yin, Mingfang Qin, Yanpeng Yin, Zhulin Hou, Ruilin Meng, Chunliang Zhou, Xiaomei Dong, Zhuoma PINGCUO, Yize Xiao, Min Yu, Biao Huang, Xiaojun Xu, Lifeng Lin, Jianpeng Xiao, Jieming Zhong, Donghui Jin, Yajie Li, Cangjue GAMA, Peng Xiong, Yiqing Xu, Lingshuang Lv, Weilin Zeng, Xing Li, Maigeng Zhou, Cunrui Huang, and Wenjun Ma
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- 2022
31. Impact of polluting fuels for cooking on diabetes mellitus and glucose metabolism in south urban China
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Si-li Tang, Zhuan‐ping Zeng, Lifeng Lin, Yi‐jin Zheng, Ruilin Meng, Wei‐jie Guan, Yanjun Xu, Xue-yan Zheng, Ting‐ting Liao, Shu-li Ma, and Chuan Li
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Adult ,Blood Glucose ,China ,Environmental Engineering ,Carbohydrate metabolism ,Logistic regression ,chemistry.chemical_compound ,Bayesian multivariate linear regression ,Environmental health ,Diabetes mellitus ,Diabetes Mellitus ,Medicine ,Humans ,Prediabetes ,Cooking ,Aged ,business.industry ,Public Health, Environmental and Occupational Health ,Building and Construction ,Odds ratio ,Middle Aged ,medicine.disease ,Confidence interval ,chemistry ,Air Pollution, Indoor ,Glycated hemoglobin ,business - Abstract
We hypothesized that exposure to polluting fuels for cooking was associated with abnormality of glucose metabolism and diabetes mellitus (DM) in south urban China. 3414 residents were surveyed in 14 urban areas of Guangdong Province in 2018. We recorded polluting fuels for cooking exposure, different DM status (DM, prediabetes), fasting blood glucose (FBG), oral glucose tolerance test (OGTT), glycated hemoglobin (HbA1c ), and other covariates by using a structured questionnaire. We conducted logistic regression model and multivariate linear regression model based on propensity-score method (inverse probability of weighting) to examine the effect of polluting fuels for cooking exposure on DM and glucose metabolism. Exposure to polluting fuels for cooking was associated with DM (odds ratio: 2.57, 95% confidence interval: 1.71 to 3.86) and prediabetes (odds ratio: 1.98, 95% confidence interval: 1.52 to 2.58) in both the adjusted and unadjusted models (all p
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- 2021
32. Future injury mortality burden attributable to compound hot extremes will significantly increase in China
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Liying, Luo, Fangfang, Zeng, Guoxia, Bai, Weiwei, Gong, Zhoupeng, Ren, Jianxiong, Hu, Guanhao, He, Heng, Shi, Ziqiang, Lin, Tao, Liu, Peng, Yin, Mingfang, Qin, Zhulin, Hou, Ruilin, Meng, Chunliang, Zhou, Xiaomei, Dong, Zhuoma, Pingcuo, Yize, Xiao, Min, Yu, Biao, Huang, Xiaojun, Xu, Lifeng, Lin, Jianpeng, Xiao, Jieming, Zhong, Donghui, Jin, Yajie, Li, Cangjue, Gama, Peng, Xiong, Yiqing, Xu, Lingshuang, Lv, Weilin, Zeng, Xing, Li, Maigeng, Zhou, Cunrui, Huang, and Wenjun, Ma
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Male ,China ,Cross-Over Studies ,Hot Temperature ,Environmental Engineering ,Climate Change ,Pollution ,Humans ,Wounds and Injuries ,Environmental Chemistry ,Female ,Mortality ,Waste Management and Disposal ,Aged ,Forecasting - Abstract
As climate change, compound hot extremes (CHEs), daytime and nighttime persistent hot extremes, are projected to become much more frequent and intense, which may pose a serious threat to human health. However, evidence on the impact of CHEs on injury is rare.We collected injury death data and daily meteorological data from six Chinese provinces during 2013-2018. A time-stratified case-crossover design with two-stage analytic approach was applied to assess the associations of CHEs with injury mortality by intention, mechanism, age and gender. Using the projected daily temperatures of five General Circulation Models (GCMs), we projected the frequency of CHEs and CHEs-attributable mortality burden of injury under three Representative Concentration Pathway (RCP) scenarios.CHEs were significantly associated with increased injury mortality risk (RR = 1.14, 95%CI: 1.09-1.19), with strong effects on unintentional injuries (RR = 1.16, 95%CI:1.11,1.22) and intentional injuries (RR = 1.11, 95%CI:0.99,1.25). Female (RR = 1.21,95%CI: 1.13-1.29) and the elderly (RR = 1.30, 95%CI: 1.22-1.39) were more susceptible to CHEs. Both the frequency and injury mortality burden of CHEs showed a steep rising trend under RCP8.5 scenario, with a 7.37-fold and 8.22-fold increase respectively, by the end of the century, especially in southern, eastern, central and northwestern China.CHEs were associated with increased injury mortality risk, and the CHEs-attributable injury mortality burden was projected to aggravate substantially in the future as global warming. It is urgent to develop targeted adaptation policies to alleviate the health burden of CHEs.
- Published
- 2022
33. The Association of Temperature Variability With Blood Pressure in Southern China: a Series of Cross-sectional Studies in Guangdong Province, China
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Ruilin Meng, Jiali Luo, Tao Liu, Guanhao He, Weilin Zeng, Jianpeng Xiao, Jianxiong Hu, Muyun Li, Xiaojun Xu, Xing Li, and Wenjun Ma
- Subjects
Series (stratigraphy) ,Blood pressure ,Geography ,genetic structures ,Southern china ,Cross-sectional study ,Environmental health ,China - Abstract
Background: Numerous studies have found a positive relationship between temperature variability and mortality, but few studies regarding the effects of temperature variability on blood pressure (BP) are available.Objective: To investigate the effects of temperature variability on BP in Guangdong province, southern China.Methods: Data on Meteorology and BP in Guangdong Province from 2004 to 2015 were collected from Guangdong Provincial Center for Disease Control and Prevention. There were 38088 participants aged 18 years and over. The generalized additive model (GAM) was used to estimate the relationship between temperature variability and BP after adjusting for confounding variables.Result: Our study found that there was a significant positively correlation between temperature variability and systolic blood pressure (SBP), and the estimate increase with the increment of exposure days in total population. The highest estimate was found at 7 days lag with increased 0.497 mmHg of SBP (95%CI: 0.335–0.660) for a 1 °C increase of TV0-7. There was insignificant association between temperature variability and diastolic blood pressure (DBP). The effects of temperature variability on BP among subpopulations with different hypertension statuses were various, and the estimates of Temperature variability with different exposure days on SBP were all higher in known hypertensives than that in normotensives.Conclusion: There was a significant association between temperature variability and SBP in Guangdong province with various effects for different populations. Our findings provide evidence that temperature variability is an independent risk factor for SBP changes, and temperature variability should be considered in hypertension clinic management and epidemiological survey.
- Published
- 2021
34. The Spring Festival Is Associated With Increased Mortality Risk in China: A Study Based on 285 Chinese Locations
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Guanhao He, Min Cai, Ruilin Meng, Jianxiong Hu, Ke Peng, Zhulin Hou, Chunliang Zhou, Xiaojun Xu, Yize Xiao, Min Yu, Biao Huang, Lifeng Lin, Tao Liu, Jianpeng Xiao, Weiwei Gong, Ruying Hu, Junhua Li, Donghui Jin, Mingfang Qin, Qinglong Zhao, Yiqing Xu, Weilin Zeng, Xing Li, Cunrui Huang, Lei Si, Xingfen Yang, and Wenjun Ma
- Subjects
General Medicine - Abstract
BackgroundThe Spring Festival is one of the most important traditional festivals in China. This study aimed to estimate the mortality risk attributable to the Spring Festival.MethodsBetween 2013 and 2017, daily meteorological, air pollution, and mortality data were collected from 285 locations in China. The Spring Festival was divided into three periods: pre-Spring Festival (16 days before Lunar New Year's Eve), mid-Spring Festival (16 days from Lunar New Year's Eve to Lantern Festival), and post-Spring Festival (16 days after Lantern Festival). The mortality risk attributed to the Spring Festival in each location was first evaluated using a distributed lag nonlinear model (DLNM), and then it was pooled using a meta-analysis model.ResultsWe observed a dip/rise mortality pattern during the Spring Festival. Pre-Spring Festival was significantly associated with decreased mortality risk (ER: −1.58%, 95%CI: −3.09% to −0.05%), and mid-Spring Festival was unrelated to mortality risks, while post-Spring Festival was significantly associated with increased mortality risk (ER: 3.63%, 95%CI: 2.15–5.12%). Overall, a 48-day Spring Festival period was associated with a 2.11% (95%CI: 0.91–3.33%) increased mortality. We also found that the elderly aged over 64 years old, women, people with cardiovascular disease (CVD), and people living in urban areas were more vulnerable to the Spring Festival.ConclusionOur study found that the Spring Festival significantly increased the mortality risk in China. These findings suggest that it is necessary to develop clinical and public health policies to alleviate the mortality burden associated with the Spring Festival.
- Published
- 2021
35. An exploratory model for the non-fatal drowning risks in children in Guangdong, China
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Hao-feng Xu, Zhishan Zhou, Xuhao Zhu, Ruilin Meng, Lifeng Lin, Yanjun Xu, Jinying Huang, and Yongjian Zhu
- Subjects
Male ,China ,Logistic regression model ,Adolescent ,Poison control ,030209 endocrinology & metabolism ,Logistic regression ,Risk Assessment ,Occupational safety and health ,03 medical and health sciences ,0302 clinical medicine ,Injury prevention ,Medicine ,Cluster Analysis ,Humans ,030212 general & internal medicine ,Child ,Students ,Children ,Swimming ,Models, Statistical ,Schools ,Drowning ,business.industry ,lcsh:Public aspects of medicine ,Public Health, Environmental and Occupational Health ,Univariate ,Human factors and ergonomics ,lcsh:RA1-1270 ,Logistic Models ,Risk factors ,Child, Preschool ,Multivariate Analysis ,Cluster sampling ,Female ,Self Report ,Biostatistics ,business ,Prediction ,Demography ,Research Article - Abstract
Background Drowning is a leading cause of accidental death in children under 14 years of age in Guangdong, China. We developed a statistical model to classify the risk of drowning among children based on the risk factors. Methods A multiple-stage cluster random sampling was employed to select the students in Grades 3 to 9 in two townships in Qingyuan, Guangdong. Questionnaire was a self-reported measure consisting of general information, knowledge, attitudes and activities. A univariate logistic regression model was used to preliminarily select the independent variables at a P value of 0.1 for multivariable model. Three-quarters of the participants were randomly selected as a training sample to establish the model, and the remaining were treated as a testing sample to validate the model. Results A total of 8390 children were included in this study, about 12.18% (1013) experienced drowning during the past one year. In the univariate logistic regression model, introvert personality, unclear distributions of water areas on the way to school, and bad relationships with their classmates and families were positively associated with drowning. However, females, older age and lower swimming skills were negatively associated with drowning. After employing the prediction model with these factors to estimate drowning risk of the students in the testing samples, the results of Hosmer-Lemeshow tests showed non-significant differences between the predictive results and actual risk (χ2 = 5.97, P = 0.65). Conclusions Male, younger children, higher swimming skills, bad relationship with their classmates and families, introvert personality and unclear distributions of water areas on the way to school were important risk factors of non-fatal drowning among children. The prediction model based on these variables has an acceptable predictive ability.
- Published
- 2019
36. Central heating and winter mortality in China: A national study based on 364 Chinese locations
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Jianxiong Hu, Weiwei Gong, Peng Yin, Guanhao He, Mingfang Qin, Zhulin Hou, Ruilin Meng, Chunliang Zhou, Yize Xiao, Min Yu, Biao Huang, Xiaojun Xu, Lifeng Lin, Tao Liu, Jianpeng Xiao, Ruying Hu, Donghui Jin, Qinglong Zhao, Yiqing Xu, Lingshuang Lv, Weilin Zeng, Xing Li, Liying Luo, Maigeng Zhou, Cunrui Huang, and Wenjun Ma
- Subjects
Urban Studies ,Atmospheric Science ,Geography, Planning and Development ,Environmental Science (miscellaneous) - Published
- 2022
37. Enhancing Both TM- and TE-Polarized Light Extraction Efficiency of AlGaN-Based Deep Ultraviolet Light-Emitting Diode via Air Cavity Extractor With Vertical Sidewall
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Wengang Bi, Ce Sun, Yuxin Zheng, Yonghui Zhang, Guoxu Liu, Zi-Hui Zhang, Kangkai Tian, Chong Geng, and Ruilin Meng
- Subjects
lcsh:Applied optics. Photonics ,Materials science ,Light-emitting diodes ,Reflector (antenna) ,02 engineering and technology ,01 natural sciences ,law.invention ,Optics ,law ,0103 physical sciences ,Ultraviolet light ,lcsh:QC350-467 ,Electrical and Electronic Engineering ,Diode ,010302 applied physics ,Total internal reflection ,Scattering ,business.industry ,Wide-bandgap semiconductor ,lcsh:TA1501-1820 ,021001 nanoscience & nanotechnology ,Atomic and Molecular Physics, and Optics ,light extraction efficiency ,AlGaN ,Reflection (physics) ,0210 nano-technology ,business ,lcsh:Optics. Light ,Light-emitting diode - Abstract
In this work, we investigate the effect of sidewall angle, height and space of an air cavity extractor (AC-Extractor) on the polarization-dependent light extraction efficiency (LEE) for AlGaN-based deep-ultraviolet light-emitting diodes (DUV LEDs) using three-dimensional finite difference time-domain method. Compared to the reported inclined sidewall metal reflector (SM-Reflector), DUV LED with AC-Extractor shows better light extraction at any height and inclined angle due to different light extraction mechanisms. The light in SM-Reflector DUV LED is extracted mainly through mirror reflection. However, total internal reflection from the sidewall dominants the contribution to LEE for the AC-Extractor with smaller inclined angle such that the space has little impact, while Fresnel scattering is more important for the AC-Extractor with larger inclined angle and that the additional out-light channel as well as the space play a critical role in enhancing the LEE. And the analysis is further developed into a three-escape-cones analytic model theory. In particular, the AC-Extractor with vertical sidewall is more beneficial to enhance the LEE of DUV LED than that with inclined sidewall, which can be rationally explained based on the three-escape-cones analytic model.
- Published
- 2018
38. Prevalence of Osteoporosis and Fracture in China
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Zhulin Hou, Shunyu Tang, Xiangjun Yin, Yuan Liu, Ruilin Meng, Ying Deng, Xianbin Ding, Zhong Dong, Qiang Lin, Zhixin Li, Shunxiang Cai, Lijia Cui, Yongqing Zhang, Lin Chen, Mengmeng Zhang, Nan Zhao, Zhongjian Xie, Lin Shen, Linhong Wang, Jieming Zhong, Ning Jiang, Steven R. Cummings, Qifeng Ying, Wei Yu, Jin Dong, Lu Cui, Zeping Ren, Yuhong Zeng, Hua Lin, Wen Wu, Weibo Xia, Xiaolan Jin, and Jingang Ma
- Subjects
education.field_of_study ,Pediatrics ,medicine.medical_specialty ,business.industry ,Population ,Osteoporosis ,Adult population ,General Medicine ,medicine.disease ,Epidemiology ,Medicine ,Rural area ,China ,business ,education - Abstract
Importance The aging of the population is associated with an increasing burden of fractures worldwide. However, the epidemiological features of fractures in mainland China are not well known. Objective To assess the prevalence of and factors associated with osteoporosis, clinical fractures, and vertebral fractures in an adult population 40 years or older in mainland China. Design, setting. and participants This cross-sectional study, the China Osteoporosis Prevalence Study, was conducted from December 2017 to August 2018. A random sample of individuals aged 20 years or older who represented urban and rural areas of China were enrolled, with a 99% participation rate. Main outcomes and measures Weighted prevalence of osteoporosis, clinical fracture, and vertebral fracture by age, sex, and urban vs rural residence as determined by x-ray absorptiometry, questionnaire, and radiography. Results A total of 20 416 participants were included in this study; 20 164 (98.8%; 11 443 women [56.7%]; mean [SD] age, 53 [13] years) had a qualified x-ray absorptiometry image and completed the questionnaire, and 8423 of 8800 (95.7%) had a qualified spine radiograph. The prevalence of osteoporosis among those aged 40 years or older was 5.0% (95% CI, 4.2%-5.8%) among men and 20.6% (95% CI, 19.3%-22.0%) among women. The prevalence of vertebral fracture was 10.5% (95% CI, 9.0%-12.0%) among men and 9.7% (95% CI, 8.2%-11.1%) among women. The prevalence of clinical fracture in the past 5 years was 4.1% (95% CI, 3.3%-4.9%) among men and 4.2% (95% CI, 3.6%-4.7%) among women. Among men and women, 0.3% (95% CI, 0.0%-0.7%) and 1.4% (95% CI, 0.8%-2.0%), respectively, with osteoporosis diagnosed on the basis of bone mineral density or with fracture were receiving antiosteoporosis treatment to prevent fracture. Conclusions and relevance In this cross-sectional study of an adult population in mainland China, the prevalence of osteoporosis and vertebral fracture were high and the prevalence of vertebral fracture and clinical fracture was similarly high in men and women. These findings suggest that current guidelines for screening and treatment of fractures among patients in China should focus equally on men and women and should emphasize the prevention of vertebral fractures.
- Published
- 2021
39. Exposure to biomass fuel is associated with high blood pressure and fasting blood glucose impairment in females in southern rural China
- Author
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Lifeng Lin, Ruilin Meng, Xue-yan Zheng, Si-li Tang, Chuan Li, Wei‐jie Guan, Yanjun Xu, and Shu-li Ma
- Subjects
Blood Glucose ,China ,Waist ,Biomass ,Blood Pressure ,010501 environmental sciences ,Logistic regression ,01 natural sciences ,Biochemistry ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Risk Factors ,Bayesian multivariate linear regression ,Environmental health ,Humans ,Medicine ,030212 general & internal medicine ,0105 earth and related environmental sciences ,General Environmental Science ,Metabolic Syndrome ,Triglyceride ,business.industry ,Fasting ,medicine.disease ,Confidence interval ,Blood pressure ,chemistry ,Hypertension ,Female ,Metabolic syndrome ,business - Abstract
We sought to investigate the association between household exposure to biomass fuel and metabolic syndrome (MetS) and its components including blood pressure, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG) and waist circumference among females in southern rural China.We surveyed 1664 residents in the Chronic Disease and Risk Factors Surveillance, conducted in 14 districts of Guangdong province. We recorded the use of biomass fuel, MetS and its components, and other covariates by using a structured questionnaire. Logistic regression model and multivariate linear regression model were adopted for analysis.Exposure to biomass fuel was significantly associated with an increase of systolic blood pressure (SBP) (β: 2.15, 95% confidence interval: 0.13 to 4.17) and FBG (β: 0.19, 95% confidence interval: 0.01 to 0.37) in the adjusted and unadjusted models (all P 0.05). Among participants with exposure to biomass fuel, being overweight or obese was associated with an increased risk of having hypertension (odds ratio: 3.19, 95% confidence interval: 2.13 to 4.76) and higher FBG levels (odds ratio: 2.10, 95% confidence interval: 1.46 to 3.02). Exposure to biomass fuel was significantly associated with a decrease of the prevalence of central obesity (P 0.05). However, exposure to biomass fuel was not associated with MetS, diastolic blood pressure and TG (all P 0.05).Exposure to biomass fuel is associated with an increase in blood pressure and FBG levels, but not MetS per se. Efforts should be made to protect females in southern rural China from the adverse effects associated with biomass fuel pollution.
- Published
- 2021
40. The association of compound hot extreme with mortality risk and vulnerability assessment at fine-spatial scale
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Zhixing Li, Yaodong Du, Wenjun Ma, Ruilin Meng, Jianpeng Xiao, Guanhao He, Xing Li, Xiaojun Xu, Cunrui Huang, Jianxiong Hu, Weilin Zeng, and Tao Liu
- Subjects
Male ,Risk ,Distributed lag ,China ,medicine.medical_specialty ,Hot Temperature ,Vulnerability index ,Population ,Vulnerability ,Context (language use) ,010501 environmental sciences ,Global Warming ,01 natural sciences ,Biochemistry ,03 medical and health sciences ,0302 clinical medicine ,Epidemiology ,medicine ,Humans ,030212 general & internal medicine ,Cities ,Mortality ,education ,Aged ,0105 earth and related environmental sciences ,General Environmental Science ,education.field_of_study ,Middle Aged ,Geography ,Relative risk ,Spatial ecology ,Female ,Demography - Abstract
The frequency and intensity of compound hot extremes will be likely to increase in the context of global warming. Epidemiological studies have demonstrated the adverse effect of simple hot extreme events on mortality, but little is known about the effects of compound hot extremes on mortality. Daily meteorological, demographic, and mortality data during 2011-2017 were collected from 160 streets in Guangzhou City, China. We used distributed lag non-linear model (DLNM) to analyze the associations of different hot extremes with mortality risk in each street. Street-specific associations were then combined using a meta-analysis approach. To assess the spatial distribution of vulnerability to compound hot extremes, vulnerable characteristics at street level were selected using random forest model, and then we calculated and mapped spatial vulnerability index (SVI) at each street in Guangzhou. At street level, compared with normal day, compound hot extreme significantly increased mortality risk (relative risk(RR)=1.43, 95%CI:1.28-1.59) with higher risk for female (RR=1.54 [1.35-1.76]) and the elderly(RR for aged 65-74=1.41 [1.14-1.74]; RR for ≥75years=1.63 [1.45-1.84]) than male (RR=1.32 [1.15-1.52]) and population
- Published
- 2021
41. Effects of Inclined Sidewall Structure With Bottom Metal Air Cavity on the Light Extraction Efficiency for AlGaN-Based Deep Ultraviolet Light-Emitting Diodes
- Author
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Ruilin Meng, Wengang Bi, Qiang Shi, Zi-Hui Zhang, Guoxu Liu, Yonghui Zhang, and Luping Li
- Subjects
lcsh:Applied optics. Photonics ,Materials science ,Light-emitting diodes ,02 engineering and technology ,medicine.disease_cause ,01 natural sciences ,law.invention ,Optics ,law ,0103 physical sciences ,medicine ,lcsh:QC350-467 ,Electrical and Electronic Engineering ,Absorption (electromagnetic radiation) ,Diode ,010302 applied physics ,Total internal reflection ,business.industry ,Scattering ,Wide-bandgap semiconductor ,lcsh:TA1501-1820 ,021001 nanoscience & nanotechnology ,Atomic and Molecular Physics, and Optics ,light extraction efficiency ,AlGaN ,Reflection (physics) ,Optoelectronics ,0210 nano-technology ,business ,Ultraviolet ,lcsh:Optics. Light ,Light-emitting diode - Abstract
An inclined sidewall scattering structure with air cavity characterized by a metal bottom and flat parallel top (Bottom_metal) is proposed to enhance the light extraction efficiency (LEE) for AlGaN-based deep ultraviolet light-emitting diodes (DUV LEDs). Compared to the reported sidewall metal inclined sidewall (Sidewall_metal) structure, the Bottom_metal structure can greatly enhance the LEE of DUV LEDs based on three-dimensional finite difference time domain simulations. Further analysis indicates that the existence of the air cavity promotes the Bottom_metal DUV LEDs to mainly utilize the total internal reflection and the Fresnel scattering to scatter the light into the escape cone, which avoids the light absorption from the sidewall metal mirror in the Sidewall_metal structure. Moreover, the unique air cavity having a bottom metal also enhances the scattering ability of the Bottom_metal DUV LEDs because any light within the cavity directing downward will be reflected back, and the parallel top interface of air cavity/AlGaN functions as additional out-light planes not limited by total internal reflection.
- Published
- 2017
42. High-performance nanoporous-GaN metal-insulator-semiconductor ultraviolet photodetectors with a thermal oxidized β-Ga
- Author
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Ruilin, Meng, Xiaoli, Ji, Zheng, Lou, Jiankun, Yang, Yonghui, Zhang, Zihui, Zhang, Wengang, Bi, Junxi, Wang, and Tongbo, Wei
- Abstract
We report on the high-performance nanoporous (NP) GaN-based metal-insulator-semiconductor (MIS) ultraviolet (UV) photodetectors (PDs) with a thermal oxidized β-Ga
- Published
- 2019
43. Epidemiological characteristics of injury mortality in Guangdong Province, China, 2015
- Author
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Chao Luo, Ye Wang, Ni Xiao, Lifeng Lin, Liang Xia, Hao-feng Xu, Yanjun Xu, Shao-en Zhou, Xiaojun Xu, Xiu-ling Song, and Ruilin Meng
- Subjects
Adult ,Male ,China ,medicine.medical_specialty ,Adolescent ,Poison control ,Injury ,030209 endocrinology & metabolism ,Suicide prevention ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Cause of Death ,Environmental health ,Epidemiology ,Injury prevention ,medicine ,Humans ,Road-traffic accident ,030212 general & internal medicine ,Mortality ,Child ,Aged ,Cause of death ,Aged, 80 and over ,Disease surveillance ,business.industry ,Prevention ,lcsh:Public aspects of medicine ,Mortality rate ,Infant, Newborn ,Public Health, Environmental and Occupational Health ,Infant ,lcsh:RA1-1270 ,Middle Aged ,Child, Preschool ,Population Surveillance ,Wounds and Injuries ,Female ,Rural area ,business ,Research Article - Abstract
Background As the fourth leading cause of death, injury is an important public health concern in Guangdong Province, China. The epidemiological characteristics of injury mortality is changing along with the social development. This study described the epidemiological characteristics of injury mortality in Guangdong Province by analyzing the death surveillance data in a few areas in Guangdong Province in 2015. Methods Using the mortality data from the Disease Surveillance Points (DSP) system, injury deaths were classified according to the International Classification of Disease-10th Revision (ICD-10). The data were stratified by areas (urban/rural), gender, age groups, injury types, and then overall and type-specific injury mortality rates were estimated for the whole Guangdong Province, China. Results We estimated that about 38,200 individuals died from injury in Guangdong Province in 2015, producing a mortality rate of 43.11/100,000. The overall age-standardized injury mortality in men was higher in rural areas compared with urban areas (41.29/100,000 versus 24.89/100,000). In terms of injury intent, unintentional injuries were the commonnest injury type, which accounted for 83.93% of the overall injury deaths, however, the deaths caused by suicide should not be ignored, which occupied 12.67% of the total injury deaths. In terms of injury cause type, falls, road-traffic accidents, suicide, drowning, and accidental poisoning were the top five leading types of injury deaths. Conclusions In Guangdong Province, injury is an important cause of death. Road-traffic accidents, falls, suicide, drowning, and accidental poisoning should be the priorities of intervention. Moreover, in rural areas, the men were the most targeted subpopulation of the prevention activities.
- Published
- 2019
44. Cancer incidence and mortality in Guangdong province, 2012
- Author
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Ruilin Meng, Wanqing Chen, Liang Xia, Yanjun Xu, Kuangrong Wei, Rongshou Zheng, and Lifeng Lin
- Subjects
0301 basic medicine ,Cancer Research ,Colorectal cancer ,Population ,Cancer registration ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Lung cancer ,education ,Stomach cancer ,Guangdong province ,education.field_of_study ,Standard Population ,business.industry ,Incidence (epidemiology) ,Cancer ,medicine.disease ,mortality ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,incidence ,Original Article ,Liver cancer ,business ,Demography ,malignancy - Abstract
OBJECTIVE To estimate the cancer incidence and mortality in 2012 in Guangdong province by analyzing the cancer data of selected population-based cancer registries in Guangdong province in 2012. METHODS Eight of nine population-based cancer registries submitted cancer data to the Guangdong Provincial Centre for Disease Control and Prevention (Guangdong CDC), whose data met the data quality criteria were included for analysis. The statistics of selected registries, stratified by areas, gender, age and cancer types, were used to estimate the cancer incidence and mortality in 2012 in Guangdong province according to the population data in Guangdong province. Segi's population and the national census population in 2000 were used for calculating the age-standardized rates (ASR). RESULTS A total of 15,084,942 people, accounted for 17.47% of all population in Guangdong province, were covered in 8 selected population-based cancer registries in 2012. The percentage of cases morphologically verified (MV%) and the percentage of death certificate-only cases (DCO%) were 72.84% and 0.87%, respectively, and the mortality/incidence (M/I) ratio was 0.56. It was estimated that there were 211,300 new cancer cases and 117,300 cancer deaths. The incidence crude rate (CR), the ASR by Chinese standard population (ASRC) and by world standard population (ASRW), and the accumulated rate (AR) (0.74 years) were 250.20/100,000 (265.39/100,000 in males, 234.29/100,000 in females), 207.04/100,000, 201.34/100,000 and 22.91%, respectively, in Guangdong province in 2012. The incidence CR and ASRC were 267.25/100,000 and 221.43/100,000 in urban areas, and 215.51/100,000 and 178.77/100,000 in rural areas, respectively. The death CR, ASRC, ASRW and AR (0.74 years) were 148.44/100,000 (190.95/100,000 in males, 105.06/100,000 in females), 103.73/100,000, 102.44/100,000 and 11.68%, respectively, in Guangdong province in 2012. The death CR and ASRC were 164.57/100,000 and 105.46/100,000 in urban areas, and 124.63/100,000 and 99.97/100,000 in rural areas, respectively. Top 5 cancers were lung cancer, liver cancer, female breast cancer, colon cancer and nasopharyngeal cancers (NPC), and top 5 death cancers were lung cancer, liver cancer, colon cancer, stomach cancer, and NPC in Guangdong province in 2012. CONCLUSIONS Lung cancer, liver cancer, female breast cancer, colon cancer and NPC were the major economic cancer burdens and health concerns in Guangdong province in 2012. Early prevention, diagnosis and treatment of different cancers, survival quality improvement and cancer burden reduction, are important issues we faced in cancer control and prevention.
- Published
- 2016
45. The association between ambient air pollution control and stroke mortality during the 2010 Asian Games in Guangzhou, China
- Author
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Hualiang Lin, Zengliang Ruan, Xiangyan Sun, Ruilin Meng, Jiayun Lv, Yin Yang, Shiyu Zhang, Qiansheng Hu, and Bipin Kumar Acharya
- Subjects
Atmospheric Science ,medicine.medical_specialty ,010504 meteorology & atmospheric sciences ,business.industry ,Public health ,Air pollution ,010501 environmental sciences ,Reference Period ,medicine.disease ,medicine.disease_cause ,01 natural sciences ,Confidence interval ,Interrupted Time Series Analysis ,Relative risk ,Environmental health ,Medicine ,business ,China ,Stroke ,0105 earth and related environmental sciences ,General Environmental Science - Abstract
Although ambient air pollution has been consistently associated with morbidity and mortality of stroke, there is limited evidence on whether the control of air pollution would associate with a reduced risk of stroke. The citywide air pollution controlling measures during the 2010 Asian Games in Guangzhou provided such an opportunity to answer this question. We collected daily data on the concentrations of air pollutants and mortality from ischemic and hemorrhagic stroke, and compared them for 51 intervention days in 2010 with the corresponding days in 2006–2009 and 2011 (reference period). Poisson-based interrupted time series analysis was employed to estimate the relative risk (RR) and 95% confidence interval (CI). The daily mean concentrations of PM10 (particles with an aerodynamic diameter smaller than 10 μm) was 88.64 μg/m3 during the reference period, and 80.47 μg/m3 during the intervention period. Daily mortality number of total stroke, ischemic and hemorrhagic stroke decreased from 3.67, 2.00 and 1.67 during the reference period, to 3.00, 1.76 and 1.24 during the intervention period; the corresponding RR was 0.79 (95% CI: 0.66–0.94), 0.87 (95% CI: 0.69–1.11) and 0.69 (95% CI: 0.52–0.91), respectively. Our findings show that ambient air pollution controlling measures during the 2010 Asian Games in Guangzhou were associated with a decreased risk of stroke mortality, which suggests a need to reduce air pollution to improve public health.
- Published
- 2019
46. Epitaxy of III-Nitrides on β-Ga2O3 and Its Vertical Structure LEDs
- Author
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Xiang Zhang, Ruilin Meng, Junxi Wang, Tongbo Wei, Jinmin Li, Jianchang Yan, and Weijiang Li
- Subjects
monoclinic ,Materials science ,Fabrication ,lcsh:Mechanical engineering and machinery ,hexagonal arrangement ,02 engineering and technology ,Substrate (electronics) ,Nitride ,Conductivity ,vertical structure LED ,Epitaxy ,01 natural sciences ,high-power ,law.invention ,III-Nitrides ,law ,0103 physical sciences ,lcsh:TJ1-1570 ,Electrical and Electronic Engineering ,010302 applied physics ,business.industry ,Mechanical Engineering ,Doping ,021001 nanoscience & nanotechnology ,Control and Systems Engineering ,β-Ga2O3 ,Optoelectronics ,Quantum efficiency ,current distribution ,0210 nano-technology ,business ,Light-emitting diode - Abstract
β-Ga2O3, characterized with high n-type conductivity, little lattice mismatch with III-Nitrides, high transparency (>80%) in blue, and UVA (400–320 nm) as well as UVB (320–280 nm) regions, has great potential as the substrate for vertical structure blue and especially ultra violet LEDs (light emitting diodes). Large efforts have been made to improve the quality of III-Nitrides epilayers on β-Ga2O3. Furthermore, the fabrication of vertical blue LEDs has been preliminarily realized with the best result that output power reaches to 4.82 W (under a current of 10 A) and internal quantum efficiency (IQE) exceeds 78% by different groups, respectively, while there is nearly no demonstration of UV-LEDs on β-Ga2O3. In this review, with the perspective from materials to devices, we first describe the basic properties, growth method, as well as doping of β-Ga2O3, then introduce in detail the progress in growth of GaN on (1 0 0) and (−2 0 1) β-Ga2O3, followed by the epitaxy of AlGaN on gallium oxide. Finally, the advances in fabrication and performance of vertical structure LED (VLED) are presented.
- Published
- 2019
47. High-performance nanoporous-GaN metal-insulator-semiconductor ultraviolet photodetectors with a thermal oxidized β-Ga2O3 layer
- Author
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Yonghui Zhang, Jiankun Yang, Zi-Hui Zhang, Xiaoli Ji, Junxi Wang, Ruilin Meng, Wengang Bi, Zheng Lou, and Tongbo Wei
- Subjects
Materials science ,business.industry ,Nanoporous ,02 engineering and technology ,Photodetection ,Specific detectivity ,021001 nanoscience & nanotechnology ,medicine.disease_cause ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,010309 optics ,Responsivity ,Semiconductor ,Optics ,0103 physical sciences ,medicine ,Optoelectronics ,Quantum efficiency ,Thin film ,0210 nano-technology ,business ,Ultraviolet - Abstract
We report on the high-performance nanoporous (NP) GaN-based metal-insulator-semiconductor (MIS) ultraviolet (UV) photodetectors (PDs) with a thermal oxidized β-Ga2O3insulating layer. The devices show a high responsivity of 4.5×105 A/W and maximum external quantum efficiency of 1.55×108% at 360 nm under a 10 V applied bias, which are attributed to the trap-assisted tunneling induced internal gain mechanism. Correspondingly, a specific detectivity of 8.27×1015 Jones and excellent optical switching repeatability are also observed in our fabricated PDs. The NP-GaN/β-Ga2O3 MIS UV PD may act as an excellent candidate for the application in UV photodetection due to the high performance and simple fabrication process.
- Published
- 2019
48. Numerical Investigations on the n+ -GaN/AlGaN/p+ -GaN Tunnel Junction for III-Nitride UV Light-Emitting Diodes
- Author
-
Chunshuang Chu, Luping Li, Wengang Bi, Yonghui Zhang, Ruilin Meng, Kangkai Tian, Qiang Shi, Zi-Hui Zhang, and Mengqian Fang
- Subjects
Materials science ,02 engineering and technology ,Nitride ,01 natural sciences ,law.invention ,Tunnel junction ,law ,Electric field ,0103 physical sciences ,Materials Chemistry ,Electrical and Electronic Engineering ,Ohmic contact ,Quantum tunnelling ,010302 applied physics ,business.industry ,Surfaces and Interfaces ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Optoelectronics ,Quantum efficiency ,0210 nano-technology ,business ,Layer (electronics) ,Light-emitting diode - Abstract
In this report, a parametric investigation on the n+-GaN/AlGaN/p+-GaN tunnel junction is made for III-nitride based ultraviolet light emitting diodes (UV LEDs). It is found that, on one hand, by using various Al compositions and AlGaN layer thicknesses, the n+-GaN/AlGaN/p+-GaN tunnel junction can modify the electric field therein, which will affect the carrier tunneling probability and the current-voltage characteristics. On the other hand, the Al composition and the AlGaN layer thickness also have a strong impact on the tunnel region width, which will affect the current flowing path and then influence the hole distribution apart from the p-type ohmic contact. This work conducts a comprehensive analysis and presents an in-depth understanding regarding the n+-GaN/AlGaN/p+-GaN tunnel junction, so that the hole concentration and the internal quantum efficiency can be significantly improved for III-nitride UV LEDs.
- Published
- 2017
49. A dielectric-constant-controlled tunnel junction for III-nitride light-emitting diodes
- Author
-
Kangkai Tian, Zi-Hui Zhang, Mengqian Fang, Chunshuang Chu, Wengang Bi, Qiang Shi, Ruilin Meng, Luping Li, and Yonghui Zhang
- Subjects
010302 applied physics ,Materials science ,Electrical junction ,business.industry ,02 engineering and technology ,Surfaces and Interfaces ,Dielectric ,Nitride ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,law.invention ,Tunnel junction ,law ,0103 physical sciences ,Materials Chemistry ,Optoelectronics ,Quantum efficiency ,Electrical and Electronic Engineering ,0210 nano-technology ,business ,Light-emitting diode - Published
- 2017
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