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1. Preparation, characterisation, crystal structure and antibacterial activity of two bis-Schiff bases containing a piperazine ring.

Author

Rui-bo Xua, Xiao-tian Yang, Hai-nan Li, Peng-cheng Zhao, Jiao-jiao Li, and Yu-xia Zhao

Subjects
*PIPERAZINE, *CRYSTAL structure, *SCHIFF bases, *STAPHYLOCOCCUS aureus, *X-ray crystallography
Abstract

Two new bis-Schiff bases containing a piperazine ring, N,N'-bis(4-chlorobenzylidene)- and N,N'-bis(4-cyanobenzylidene)-1,4-bis(3-aminopropyl)piperazine, were prepared by the reaction of N,N'-bis(3-aminopropyl)piperazine with 4-chloro- and 4-cyanobenzaldehyde, respectively. The dichloro compound was fully identified by X-ray crystallography and it exhibited good antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. [ABSTRACT FROM AUTHOR]

Published
2018
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