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14 results on '"Rueegg, Marco"'

1. Long-term course of ambulatory patients with COVID-19 initially treated with enoxaparin vs no anticoagulation: final analysis of the OVID (enoxaparin for outpatients with COVID-19) randomized trial

Author

Barco, Stefano, Voci, Davide, Held, Ulrike, Sebastian, Tim, Bingisser, Roland, Colucci, Giuseppe, Duerschmied, Daniel, Frenk, André, Gerber, Bernhard, Götschi, Andrea, Konstantinides, Stavros V., Mach, François, Robert-Ebadi, Helia, Rosemann, Thomas, Simon, Noemi R., Spechbach, Hervé, Spirk, David, Stortecky, Stefan, Vaisnora, Lukas, Righini, Marc, Kucher, Nils, Zetzsche, Stéphanie Roth, Spescha, Rebecca, Leeger, Claudia, Butscheid, Yulia, Probst, Eliane, Micieli, Evy, Forgo, Gabor, Johner, Fabian, Grigorean, Alexandru, Vatsakis, Georgios, Lang, Dagmar Keller, Speck, Silvana Rampini, Hasse, Barbara, Rueegg, Marco, Arnold, Isabelle, Nickel, Christian, Busch, Jeannette, Blondon, Marc, Glauser, Frédéric, Cittone, Micol G., Kessler, Chiara, Gjermeni, Diona, Olivier, Christoph B., Gauchel, Nadine, Biever, Paul, Hobohm, Lukas, Becker, Dorothea, Schindewolf, Marc, Kuenzi, Arnaud, Ulrich, Silvia, Fumagalli, Riccardo M., Bikdeli, Behnood, Gerardi, Teresa, Klok, Frederikus A., Wolf, Simon, and Wyss, Dörte

Published
2024
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2. Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial

Author

Barco, Stefano, Voci, Davide, Held, Ulrike, Sebastian, Tim, Bingisser, Roland, Colucci, Giuseppe, Duerschmied, Daniel, Frenk, André, Gerber, Bernhard, Götschi, Andrea, Konstantinides, Stavros V, Mach, François, Robert-Ebadi, Helia, Rosemann, Thomas, Simon, Noemi R, Spechbach, Hervé, Spirk, David, Stortecky, Stefan, Vaisnora, Lukas, Righini, Marc, Kucher, Nils, Roth Zetzsche, Stéphanie, Spescha, Rebecca, Leeger, Claudia, Butscheid, Yulia, Probst, Eliane, Micieli, Evy, Forgo, Gabor, Johner, Fabian, Grigorean, Alexandru, Vatsakis, Georgios, Keller Lang, Dagmar, Rampini Speck, Silvana, Hasse, Barbara, Rueegg, Marco, Arnold, Isabelle, Nickel, Christian, Busch, Jeannette, Blondon, Marc, Glauser, Frédéric, Cittone, Micol G, Kessler, Chiara, Gjermeni, Diona, Olivier, Christoph B, Gauchel, Nadine, Biever, Paul, Hobohm, Lukas, Becker, Dorothea, Schindewolf, Marc, Kuenzi, Arnaud, and Ulrich, Silvia

Published
2022
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5. Inverse relationship between IL-6 and sodium levels in patients with COVID-19 and other respiratory tract infections: data from the COVIVA study

Author

Atila, Cihan, primary, Monnerat, Sophie, additional, Bingisser, Roland, additional, Siegemund, Martin, additional, Lampart, Maurin, additional, Rueegg, Marco, additional, Zellweger, Núria, additional, Osswald, Stefan, additional, Rentsch, Katharina, additional, Christ-Crain, Mirjam, additional, and Twerenbold, Raphael, additional

Published
2022
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6. Prognosis for older people at presentation to emergency department based on frailty and aggregated vital signs.

Author

Kabell Nissen, Søren, Rueegg, Marco, Carpenter, Christopher R., Kaeppeli, Tobias, Busch, Jeanette‐Marie, Fournaise, Anders, Dreher‐Hummel, Thomas, Bingisser, Roland, Brabrand, Mikkel, and Nickel, Christian H.

Subjects
*MORTALITY prevention, *EXPERIMENTAL design, *HOSPITAL emergency services, *FRAIL elderly, *CONFIDENCE intervals, *VITAL signs, *RESEARCH methodology, *RESEARCH methodology evaluation, *MULTIPLE regression analysis, *TERTIARY care, *RISK assessment, *QUALITATIVE research, *COMPARATIVE studies, *DESCRIPTIVE statistics, *RESEARCH funding, *RECEIVER operating characteristic curves, *ODDS ratio, *LONGITUDINAL method, *OLD age, MORTALITY risk factors
Abstract

Background: Risk stratification for older people based on aggregated vital signs lack the accuracy to predict mortality at presentation to the Emergency Department (ED). We aimed to develop and internally validate the Frailty adjusted Prognosis in ED tool (FaP‐ED) for 30‐day mortality combining frailty and aggregated vital signs. Methods: Single‐center prospective cohort of undifferentiated ED patients aged 65 or older, consecutively sampled upon ED presentation from a tertiary Emergency Center. Vital signs were aggregated using the National Early Warning Score (NEWS) as a measure of illness or injury severity and frailty was assessed with the Clinical Frailty Scale (CFS). The FaP‐ED was constructed by combining NEWS and CFS in multivariable logistic regression. The primary outcome was 30‐day mortality. Measures of discrimination and calibration were assessed to evaluate predictive performance and internally validated using bootstrapping. Results: 2250 patients were included, 67 (1.8%) were omitted from analyses due to missing CFS, loss to follow‐up, or terminal illness. Thirty‐day mortality rate was 5.4% (N = 122, 95% CI = 4.5%–6.4%). Median NEWS was 1 (Inter‐Quartile Range (IQR): 0–3) and median CFS was 4 (IQR: 3–5). The Area Under Receiver Operating Characteristic (AUROC) for FaP‐ED was 0.86 (95% CI = 0.83–0.90). This was significantly higher than NEWS (0.81, 95% CI = 0.77–0.85, DeLong: Z = 3.5, p < 0.001) or CFS alone (0.82, 95% CI = 0.78–0.86, DeLong: Z = 4.4, p < 0.001). Bootstrapped estimates of FaP‐ED AUROC, calibration slope, and intercept were 0.86, 0.95, and −0.09, respectively, suggesting internal validity. A decision‐threshold of CFS 5 and NEWS 3 was proposed based on qualitative comparison of positive Likelihood Ratio at all relevant FaP‐ED cutoffs. Conclusion: Combining aggregated vital signs and frailty accurately predicted 30‐day mortality at ED presentation and illustrated an important clinical interaction between frailty and illness severity. Pending external validation, the Fap‐ED operationalizes the concept of such "geriatric urgency" for the ED setting. [ABSTRACT FROM AUTHOR]

Published
2023
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10. Prevalence and outcome of dysnatremia in patients with COVID-19 compared to controls

Author

Atila, Cihan, primary, Sailer, Clara O, additional, Bassetti, Stefano, additional, Tschudin-Sutter, Sarah, additional, Bingisser, Roland, additional, Siegemund, Martin, additional, Osswald, Stefan, additional, Rentsch, Katharina, additional, Rueegg, Marco, additional, Schaerli, Sabrina, additional, Kuster, Gabriela M, additional, Twerenbold, Raphael, additional, and Christ-Crain, Mirjam, additional

Published
2021
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12. COVID-19 Triage and Test Center: Safety, Feasibility, and Outcomes of Low-Threshold Testing

Author

Mansella, Gregory, primary, Rueegg, Marco, additional, Widmer, Andreas F., additional, Tschudin-Sutter, Sarah, additional, Battegay, Manuel, additional, Hoff, Julia, additional, Søgaard, Kirstine K., additional, Egli, Adrian, additional, Stieltjes, Bram, additional, Leuzinger, Karoline, additional, Hirsch, Hans H., additional, Meienberg, Andrea, additional, Burkard, Thilo, additional, Mayr, Michael, additional, Bingisser, Roland, additional, and Nickel, Christian H., additional

Published
2020
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