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10. Bronchiolitis obliterans organizing pneumonia (BOOP) after thoracic radiotherapy for breast carcinoma

Author

Tan Youke KY, Liem Hauw, Antonisse Imogeen E, Senan Suresh, Cornelissen Robin, Rudolphus Arjan, and Aerts Joachim GJV

Subjects
Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans organizing pneumonia (BOOP). We report on two patients with carcinoma of the breast who developed an interstitial lung disease consistent with BOOP. BOOP responds to treatment with corticosteroids and the prognosis is generally good despite of the need for long-term administration of corticosteroids as relapses can occur during tapering of steroids. This report provides guidelines for the evaluation and treatment of patients with pulmonary infiltrates after radiotherapy.

Published
2007
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12. Proteinase/proteinase inhibitor imbalance in sputum sol phases from patients with chronic obstructive pulmonary disease: suggestions for a key role played by antileukoprotease

Author

Piccioni, Pier Dante, Kramps, Johannes A., Rudolphus, Arjan, Bulgheroni, Antonella, and Luisetti, Maurizio

Subjects
Proteases -- Physiological aspects -- Analysis, Lung diseases, Obstructive -- Physiological aspects -- Analysis, Sputum -- Analysis -- Physiological aspects, Health, Physiological aspects, Analysis
Abstract

In order to characterize the imbalance between proteinases and proteinase inhibitors in sputum sol phases, we studied 25 patients (mean age, 59±11 yr) with exacerbated chronic obstructive pulmonary disease (COPD). [...]

Published
1992

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