2,684 results on '"Rubin, Michael"'
Search Results
2. Social Cohesion and Community Displacement in Armed Conflict
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Arnon, Daniel, McAlexander, Richard J., and Rubin, Michael A.
- Published
- 2023
3. Why the U.S. Obsession with Iran Leads it to Misconstrue and Misjudge Shi’ite Politics
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Rubin, Michael
- Published
- 2021
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4. The Places of "Thing" and "Something" in Aquinas's Order of the Transcendentals
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Rubin, Michael J.
- Published
- 2017
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5. Equity in Clinical Care and Research Involving Persons with Disorders of Consciousness
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Rubin, Michael A., Lewis, Ariane, Creutzfeldt, Claire J., Shrestha, Gentle S., Boyle, Quinn, Illes, Judy, Jox, Ralf J., Trevick, Stephen, and Young, Michael J.
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- 2024
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6. Are Kurds a Pariah Minority?
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Rubin, Michael
- Published
- 2015
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7. Antimicrobial use before and during COVID-19: data from 108 Veterans Affairs medical centers
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Goetz, Matthew Bidwell, Willson, Tina, Rubin, Michael A, Stevens, Vanessa W, and Graber, Christopher J
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Biomedical and Clinical Sciences ,Clinical Sciences ,Infectious Diseases ,Coronaviruses ,Emerging Infectious Diseases ,Infection ,Good Health and Well Being - Abstract
Abstract: Objective:: Inpatient antibiotic use increased during the early phases of the COVID-19 pandemic. We sought to determine whether these changes persisted in persons with and without COVID-19 infection. Design:: Retrospective cohort analysis. Setting:: 108 Veterans Affairs (VA) facilities. Patients:: Persons receiving acute inpatient care from January 2016 to October 2022. Methods:: Data on antibacterial use, patient days present, and COVID-19 care were extracted from the VA Corporate Data Warehouse. Days of therapy (DOT) per 1000 days present (DP) were calculated and stratified by Centers for Disease Control and Prevention-defined antibiotic classes. Results:: Antibiotic use increased from 534 DOT/1000 DP in 11/2019–2/2020 to 588 DOT/1000 DP in 3/2020–4/2020. Subsequently, antibiotic use decreased such that total DOT/1000 DP was 2% less in 2020 as a whole than in 2019. Driven by treatment for community acquired pneumonia, antibiotic use was 30% higher in persons with COVID-19 than in uninfected persons in 3/2020–4/2020, but only 4% higher for the remainder of 2020. In 2022 system-wide antibiotic use was 9% less in persons with COVID-19; however, antibiotic use remained higher in persons with COVID-19 in 25% of facilities. Discussion:: Although antibiotic use increased during the early phases of the COVID-19 pandemic, overall use subsequently decreased to below previous baseline levels and, in 2022, was less in persons with COVID-19 than in persons without COVID-19. However, further work needs to be done to address variances across facilities and to determine whether current levels of antibiotic use in persons with COVID-19 are justified.
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- 2024
8. Liberia: Next Steps Toward Accountability for War and Economic Crimes
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Rubin, Michael
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Liberia -- Economic aspects -- Political aspects ,Liberian Civil War, 1999-2003 ,Political corruption -- Economic aspects ,War crimes -- Investigations ,Company legal issue ,Social sciences - Abstract
Thursday, June 13, 2024 Chairman Smith, Chairman McGovern, and honorable members, thank you for the opportunity to testify today. While the topic of today's hearing is the effort to win [...]
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- 2024
9. Student Attitudes Contribute to the Effectiveness of a Genomics CURE
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Lopatto, David, Rosenwald, Anne G., Burgess, Rebecca C., Silver Key, Catherine, Van Stry, Melanie, Wawersik, Matthew, DiAngelo, Justin R., Hark, Amy T., Skerritt, Matthew, Allen, Anna K., Alvarez, Consuelo, Anderson, Sara, Arrigo, Cindy, Arsham, Andrew, Barnard, Daron, Bedard, James E. J., Bose, Indrani, Braverman, John M., Burg, Martin G., Croonquist, Paula, Du, Chunguang, Dubowsky, Sondra, Eisler, Heather, Escobar, Matthew A., Foulk, Michael, Giarla, Thomas, Glaser, Rivka L., Goodman, Anya L., Gosser, Yuying, Haberman, Adam, Hauser, Charles, Hays, Shan, Howell, Carina E., Jemc, Jennifer, Jones, Christopher J., Kadlec, Lisa, Kagey, Jacob D., Keller, Kimberly L., Kennell, Jennifer, Kleinschmit, Adam J., Kleinschmit, Melissa, Kokan, Nighat P., Kopp, Olga Ruiz, Laakso, Meg M., Leatherman, Judith, Long, Lindsey J., Manier, Mollie, Martinez-Cruzado, Juan C., Matos, Luis F., McClellan, Amie Jo, McNeil, Gerard, Merkhofer, Evan, Mingo, Vida, Mistry, Hemlata, Mitchell, Elizabeth, Mortimer, Nathan T., Myka, Jennifer Leigh, Nagengast, Alexis, Overvoorde, Paul, Paetkau, Don, Paliulis, Leocadia, Parrish, Susan, Toering Peters, Stephanie, Preuss, Mary Lai, Price, James V., Pullen, Nicholas A., Reinke, Catherine, Revie, Dennis, Robic, Srebrenka, Roecklein-Canfield, Jennifer A., Rubin, Michael R., Sadikot, Takrima, Siders Sanford, Jamie, Santisteban, Maria, Saville, Kenneth, Schroeder, Stephanie, Shaffer, Christopher D., Sharif, Karim A., Sklensky, Diane E., Small, Chiyedza, Smith, Sheryl, Spokony, Rebecca, Sreenivasan, Aparna, Stamm, Joyce, Sterne-Marr, Rachel, Teeter, Katherine C., Thackeray, Justin, Thompson, Jeffrey S., Velazquez-Ulloa, Norma, Wolfe, Cindy, Youngblom, James, Yowler, Brian, Zhou, Leming, Brennan, Janie, Buhler, Jeremy, Leung, Wilson, Elgin, Sarah C. R., and Reed, Laura K.
- Abstract
The Genomics Education Partnership (GEP) engages students in a course-based undergraduate research experience (CURE). To better understand the student attributes that support success in this CURE, we asked students about their attitudes using previously published scales that measure epistemic beliefs about work and science, interest in science, and grit. We found, in general, that the attitudes students bring with them into the classroom contribute to two outcome measures, namely, learning as assessed by a pre- and postquiz and perceived self-reported benefits. While the GEP CURE produces positive outcomes overall, the students with more positive attitudes toward science, particularly with respect to epistemic beliefs, showed greater gains. The findings indicate the importance of a student's epistemic beliefs to achieving positive learning outcomes.
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- 2022
10. Antimicrobial physician and pharmacist experience and perception of an antimicrobial Self-Stewardship Time-Out Program (SSTOP) intervention at eight Veterans' Affairs medical centers.
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Goedken, Cassie Cunningham, Butler, Jorie M, Judd, Joshua, Brown, Nui, Rubin, Michael, and Goetz, Matthew Bidwell
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Prevention ,Antimicrobial Resistance ,Infectious Diseases ,Emerging Infectious Diseases ,Clinical Research ,Medical and Health Sciences ,Epidemiology - Abstract
We explored experiences and perceptions surrounding the Self-Stewardship Time-Out Program (SSTOP) intervention across implementation sites to improve antimicrobial use. Semistructured qualitative interviews were conducted with Antibiotic Stewardship physicians and pharmacists, from which 5 key themes emerged. SSTOP may serve to achieve sustainable promotion of antibiotic use improvements.
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- 2023
11. Boxed in: Containing a nuclear Iran
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Rubin, Michael
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NUCLEAR WEAPONS - Iran ,IRAN - Foreign Relations - United States ,UNITED STATES - Foreign Relations - Iran ,IRAN - Foreign Policy - Abstract
illus chart
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- 2008
12. Section Editors
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Bortolin, Michelangelo, primary, Cattamanchi, Srihari, additional, Cetaruk, Edward W., additional, Hart, Alexander, additional, Hertelendy, PhD, Attila J., additional, Issa, Fadi S., additional, “Jake” Jacoby, Irving, additional, Jenkins, J. Lee, additional, Kappler, Shane, additional, Madsen, James M., additional, Mahon, Selwyn E., additional, Norton, Ian, additional, Ragazzoni, Luca, additional, Rubin, Michael, additional, Sanchez, Leon D., additional, Stewart, Charles, additional, and Weinstein, Eric S., additional
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- 2024
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13. Eternal Iran: Continuity and chaos
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Clawson, Patrick and Rubin, Michael
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BOOK REVIEWS - Published
- 2007
14. Proceedings of the Second Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness.
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Mainali, Shraddha, Aiyagari, Venkatesh, Alexander, Sheila, Bodien, Yelena, Boerwinkle, Varina, Boly, Melanie, Brown, Emery, Brown, Jeremy, Claassen, Jan, Edlow, Brian, Fink, Ericka, Fins, Joseph, Foreman, Brandon, Frontera, Jennifer, Geocadin, Romergryko, Giacino, Joseph, Gilmore, Emily, Gosseries, Olivia, Hammond, Flora, Helbok, Raimund, Claude Hemphill, J, Hirsch, Karen, Kim, Keri, Laureys, Steven, Lewis, Ariane, Ling, Geoffrey, Livesay, Sarah, McCredie, Victoria, McNett, Molly, Menon, David, Molteni, Erika, Olson, DaiWai, OPhelan, Kristine, Park, Soojin, Polizzotto, Len, Javier Provencio, Jose, Puybasset, Louis, Venkatasubba Rao, Chethan, Robertson, Courtney, Rohaut, Benjamin, Rubin, Michael, Sharshar, Tarek, Shutter, Lori, Sampaio Silva, Gisele, Smith, Wade, Stevens, Robert, Thibaut, Aurore, Vespa, Paul, Wagner, Amy, Ziai, Wendy, Zink, Elizabeth, and I Suarez, Jose
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Coma ,Curing Coma Campaign ,Disorders of consciousness ,National Institute of Health ,Proceedings ,Coma ,Consciousness ,Consciousness Disorders ,Humans ,National Institutes of Health (U.S.) ,United States - Abstract
This proceedings article presents actionable research targets on the basis of the presentations and discussions at the 2nd Curing Coma National Institutes of Health (NIH) symposium held from May 3 to May 5, 2021. Here, we summarize the background, research priorities, panel discussions, and deliverables discussed during the symposium across six major domains related to disorders of consciousness. The six domains include (1) Biology of Coma, (2) Coma Database, (3) Neuroprognostication, (4) Care of Comatose Patients, (5) Early Clinical Trials, and (6) Long-term Recovery. Following the 1st Curing Coma NIH virtual symposium held on September 9 to September 10, 2020, six workgroups, each consisting of field experts in respective domains, were formed and tasked with identifying gaps and developing key priorities and deliverables to advance the mission of the Curing Coma Campaign. The highly interactive and inspiring presentations and panel discussions during the 3-day virtual NIH symposium identified several action items for the Curing Coma Campaign mission, which we summarize in this article.
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- 2022
15. Towards an Independent Kurdistan: Self-Determination in International Law
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Rubin, Michael
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Kurds ,International relations ,Political science ,Regional focus/area studies - Abstract
Towards an Independent Kurdistan: Self-Determination in International Law. By Loqman Radpey. New York: Routledge, 2024. 301 pp. $170. The Kurds are the largest ethnic group to lack their own nation-state. [...]
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- 2024
16. Instructional Models for Course-Based Research Experience (CRE) Teaching
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Hanauer, David I, Graham, Mark J, Arnold, Rachel J, Ayuk, Mary A, Balish, Mitchell F, Beyer, Andrea R, Butela, Kristen A, Byrum, Christine A, Chia, Catherine P, Chung, Hui-Min, Clase, Kari L, Conant, Stephanie, Coomans, Roy J, D’Elia, Tom, Diaz, Jason, Diaz, Arturo, Doty, Jean A, Edgington, Nicholas P, Edwards, Dustin C, Eivazova, Elvira, Emmons, Christine B, Fast, Kayla M, Fisher, Emily J, Fleischacker, Christine L, Frederick, Gregory D, Freise, Amanda C, Gainey, Maria D, Gissendanner, Chris R, Golebiewska, Urszula P, Guild, Nancy A, Hendrickson, Heather L, Herren, Christopher D, Hopson-Fernandes, Margaret S, Hughes, Lee E, Jacobs-Sera, Deborah, Johnson, Allison A, Kirkpatrick, Bridgette L, Klyczek, Karen K, Koga, Ann P, Kotturi, Hari, LeBlanc-Straceski, Janine, Lee-Soety, Julia Y, Leonard, Justin E, Mastropaolo, Matthew D, Merkhofer, Evan C, Michael, Scott F, Mitchell, Jon C, Mohan, Swarna, Monti, Denise L, Noutsos, Christos, Nsa, Imade Y, Peters, Nick T, Plymale, Ruth, Pollenz, Richard S, Porter, Megan L, Rinehart, Claire A, Rosas-Acosta, German, Ross, Joseph F, Rubin, Michael R, Scherer, Anne E, Schroeder, Stephanie C, Shaffer, Christopher D, Sprenkle, Amy B, Sunnen, C Nicole, Swerdlow, Sarah J, Tobiason, Deborah, Tolsma, Sara S, Tsourkas, Philippos K, Ward, Robert E, Ware, Vassie C, Warner, Marcie H, Washington, Jacqueline M, Westover, Kristi M, White, Simon J, Whitefleet-Smith, JoAnn L, Williams, Daniel C, Wolyniak, Michael J, Zeilstra-Ryalls, Jill H, Asai, David J, Hatfull, Graham F, and Sivanathan, Viknesh
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Curriculum and Pedagogy ,Education Systems ,Education ,Quality Education ,Engineering ,Faculty ,Humans ,Mathematics ,Models ,Educational ,Students ,Teaching ,Curriculum and pedagogy - Abstract
The course-based research experience (CRE) with its documented educational benefits is increasingly being implemented in science, technology, engineering, and mathematics education. This article reports on a study that was done over a period of 3 years to explicate the instructional processes involved in teaching an undergraduate CRE. One hundred and two instructors from the established and large multi-institutional SEA-PHAGES program were surveyed for their understanding of the aims and practices of CRE teaching. This was followed by large-scale feedback sessions with the cohort of instructors at the annual SEA Faculty Meeting and subsequently with a small focus group of expert CRE instructors. Using a qualitative content analysis approach, the survey data were analyzed for the aims of inquiry instruction and pedagogical practices used to achieve these goals. The results characterize CRE inquiry teaching as involving three instructional models: 1) being a scientist and generating data; 2) teaching procedural knowledge; and 3) fostering project ownership. Each of these models is explicated and visualized in terms of the specific pedagogical practices and their relationships. The models present a complex picture of the ways in which CRE instruction is conducted on a daily basis and can inform instructors and institutions new to CRE teaching.
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- 2022
17. Inpatient antibiotic utilization in the Veterans' Health Administration during the coronavirus disease 2019 (COVID-19) pandemic.
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Dieringer, Thomas D, Furukawa, Daisuke, Graber, Christopher J, Stevens, Vanessa W, Jones, Makoto M, Rubin, Michael A, and Goetz, Matthew Bidwell
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Epidemiology ,Medical and Health Sciences - Abstract
Antibiotic prescribing practices across the Veterans' Health Administration (VA) experienced significant shifts during the coronavirus disease 2019 (COVID-19) pandemic. From 2015 to 2019, antibiotic use between January and May decreased from 638 to 602 days of therapy (DOT) per 1,000 days present (DP), while the corresponding months in 2020 saw antibiotic utilization rise to 628 DOT per 1,000 DP.
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- 2021
18. Safeguarding the People of Nagorno-Karabakh
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Rubin, Michael
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Nagorno-Karabakh Conflict, 2020 ,Nagorno-Karabakh Blockade, 2022-2023 ,Military assistance -- Analysis ,Political violence -- Analysis ,Referendum -- Analysis ,Treaties -- Analysis ,Ethnic relations -- Analysis ,Peacekeeping forces -- Analysis ,Social sciences - Abstract
The American Enterprise Institute (AEI) is a nonpartisan, nonprofit, 501(c)(3) educational organization and does not take institutional positions on any issues. The views expressed in this testimony are those of [...]
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- 2023
19. Instructional Models for Course-Based Research Experience (CRE) Teaching
- Author
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Hanauer, David I., Graham, Mark J., Arnold, Rachel J., Ayuk, Mary A., Balish, Mitchell F., Beyer, Andrea R., Butela, Kristen A., Byrum, Christine A., Chia, Catherine P., Chung, Hui-Min, Clase, Kari L., Conant, Stephanie, Coomans, Roy J., D'Elia, Tom, Diaz, Jason, Diaz, Arturo, Doty, Jean A., Edgington, Nicholas P., Edwards, Dustin C., Eivazova, Elvira, Emmons, Christine B., Fast, Kayla M., Fisher, Emily J., Fleischacker, Christine L., Frederick, Gregory D., Freise, Amanda C., Gainey, Maria D., Gissendanner, Chris R., Golebiewska, Urszula P., Guild, Nancy A., Hendrickson, Heather L., Herren, Christopher D., Hopson-Fernandes, Margaret S., Hughes, Lee E., Jacobs-Sera, Deborah, Johnson, Allison A., Kirkpatrick, Bridgette L., Klyczek, Karen K., Koga, Ann P., Kotturi, Hari, LeBlanc-Straceski, Janine, Lee-Soety, Julia Y., Leonard, Justin E., Mastropaolo, Matthew D., Merkhofer, Evan C., Michael, Scott F., Mitchell, Jon C., Mohan, Swarna, Monti, Denise L., Noutsos, Christos, Nsa, Imade Y., Peters, Nick T., Plymale, Ruth, Pollenz, Richard S., Porter, Megan L., Rinehart, Claire A., Rosas-Acosta, German, Ross, Joseph F., Rubin, Michael R., Scherer, Anne E., Schroeder, Stephanie C., Shaffer, Christopher D., Sprenkle, Amy B., Sunnen, C. Nicole, Swerdlow, Sarah J., Tobiason, Deborah, Tolsma, Sara S., Tsourkas, Philippos K., Ward, Robert E., Ware, Vassie C., Warner, Marcie H., Washington, Jacqueline M., Westover, Kristi M., White, Simon J., Whitefleet-Smith, JoAnn L., Williams, Daniel C., Wolyniak, Michael J., Zeilstra-Ryalls, Jill H., Asai, David J., Hatfull, Graham F., and Sivanathan, Viknesh
- Abstract
The course-based research experience (CRE) with its documented educational benefits is increasingly being implemented in science, technology, engineering, and mathematics education. This article reports on a study that was done over a period of 3 years to explicate the instructional processes involved in teaching an undergraduate CRE. One hundred and two instructors from the established and large multi-institutional SEA-PHAGES program were surveyed for their understanding of the aims and practices of CRE teaching. This was followed by large-scale feedback sessions with the cohort of instructors at the annual SEA Faculty Meeting and subsequently with a small focus group of expert CRE instructors. Using a qualitative content analysis approach, the survey data were analyzed for the aims of inquiry instruction and pedagogical practices used to achieve these goals. The results characterize CRE inquiry teaching as involving three instructional models: (1) being a scientist and generating data; (2) teaching procedural knowledge; and (3) fostering project ownership. Each of these models is explicated and visualized in terms of the specific pedagogical practices and their relationships. The models present a complex picture of the ways in which CRE instruction is conducted on a daily basis and can inform instructors and institutions new to CRE teaching.
- Published
- 2022
- Full Text
- View/download PDF
20. Frontline perspectives of C. difficile infection prevention practice implementation within veterans affairs health care facilities: A qualitative study
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Parmasad, Vishala, Keating, Julie, McKinley, Linda, Evans, Charlesnika, Rubin, Michael, Voils, Corrine, and Safdar, Nasia
- Published
- 2023
- Full Text
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21. Futility and Shared Decision-Making
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Rubin, Michael A., Riecke, Jenny, and Heitman, Elizabeth
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- 2023
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22. Low-cost photoreactors for highly photon/energy-efficient solar-driven synthesis
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Kant, Paul, Liang, Shengzhi, Rubin, Michael, Ozin, Geoffrey Alan, and Dittmeyer, Roland
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- 2023
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23. SOEC-based production of e-fuels via the Fischer–Tropsch route
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Dhamo, Dorela, primary, Hess, Dominik, additional, Rubin, Michael, additional, and Dittmeyer, Roland, additional
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- 2023
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24. Arguments Supporting the Whole-Brain Criterion
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Rubin, Michael A., Reyes, Ranier, Dubljević, Veljko, Series Editor, Jotterand, Fabrice, Series Editor, Jox, Ralf J., Series Editor, Racine, Eric, Series Editor, Lewis, Ariane, editor, and Bernat, James L., editor
- Published
- 2022
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- View/download PDF
25. Isophotonic reactor for the precise determination of quantum yields in gas, liquid, and multi-phase photoreactions
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Kant, Paul, Trinkies, Laura L., Gensior, Nils, Fischer, Domenik, Rubin, Michael, Alan Ozin, Geoffrey, and Dittmeyer, Roland
- Published
- 2023
- Full Text
- View/download PDF
26. Author Response: What Is the Ideal Brain Criterion of Death? Nonclinical Considerations: The UDDA Revision Series
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Rubin, Michael A., primary
- Published
- 2024
- Full Text
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27. Investigation of cationic transformations involving 5-ethynyl-4-arylpyrimidines
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Shcherbakov, Stanislav V., Magometov, Artyom Yu, Vendin, Maksim V., Shcherbakova, Viktoria Yu, Aksenov, Nicolai A., Aksenov, Alexander V., Naji, Osama, and Rubin, Michael
- Published
- 2022
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28. Epidemiology and outcomes associated with carbapenem-resistant Acinetobacter baumannii and carbapenem-resistant Pseudomonas aeruginosa: a retrospective cohort study
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Vivo, Amanda, Fitzpatrick, Margaret A., Suda, Katie J., Jones, Makoto M., Perencevich, Eli N., Rubin, Michael A., Ramanathan, Swetha, Wilson, Geneva M., Evans, Martin E., and Evans, Charlesnika T.
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- 2022
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29. They're Still There, He's All Gone: American Fatalities in Foreign Wars and Right-Wing Radicalization at Home.
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MCALEXANDER, RICHARD J., RUBIN, MICHAEL A., and WILLIAMS, ROB
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IRAQ War, 2003-2011 , *AFGHAN War, 2001-2021 , *SOCIAL media , *ECONOMICS of war , *WAR & society - Abstract
What explains right-wing radicalization in the United States? Existing research emphasizes demographic changes, economic insecurity, and elite polarization. This paper highlights an additional factor: the impact of foreign wars on society at home. We argue communities that bear the greatest costs of foreign wars are prone to higher rates of right-wing radicalization. To support this claim, we present robust correlations between activity on Parler, a predominantly right-wing social media platform, and fatalities among residents who served in U.S. wars in Iraq and Afghanistan, at both the county and census tract level. The findings contribute to understanding right-wing radicalization in the US in two key respects. First, it examines widespread, nonviolent radical-right activity that, because it is less provocative than protest and violence, has eluded systematic measurement. Second, it highlights that U.S. foreign wars have important implications for domestic politics beyond partisanship and voting, to potentially include radicalization. [ABSTRACT FROM AUTHOR]
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- 2024
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30. Is Taiwan Part of China?
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Rubin, Michael
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Emigration and immigration -- Analysis ,Autonomy -- Analysis ,Government regulation ,Social sciences ,Communist Party of China -- Laws, regulations and rules - Abstract
That Taiwan is an inalienable part of China remains a sine qua non of Beijing's diplomacy. Since Mao Zedong proclaimed the People's Republic of China (PRC) on October 1, 1949, [...]
- Published
- 2022
31. Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives
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Aksenov, Alexander V., Kirilov, Nikita K., Aksenov, Nicolai A., Arutiunov, Nikolai A., Aksenov, Dmitrii A., and Rubin, Michael
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- 2022
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32. Research agenda for transmission prevention within the Veterans Health Administration, 2024–2028
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Smith, Matthew, primary, Crnich, Chris, additional, Donskey, Curtis, additional, Evans, Charlesnika T., additional, Evans, Martin, additional, Goto, Michihiko, additional, Guerrero, Bernardino, additional, Gupta, Kalpana, additional, Harris, Anthony, additional, Hicks, Natalie, additional, Khader, Karim, additional, Kralovic, Stephen, additional, McKinley, Linda, additional, Rubin, Michael, additional, Safdar, Nasia, additional, Schweizer, Marin L., additional, Tovar, Suzanne, additional, Wilson, Geneva, additional, Zabarsky, Trina, additional, and Perencevich, Eli N., additional
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- 2024
- Full Text
- View/download PDF
33. Beyond the Final Heartbeat: Neurological Perspectives on Normothermic Regional Perfusion for Organ Donation after Circulatory Death
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Kirschen, Matthew P., primary, Lewis, Ariane, additional, Rubin, Michael A., additional, Varelas, Panayiotis N., additional, and Greer, David M., additional
- Published
- 2024
- Full Text
- View/download PDF
34. Rebel Territorial Control and Civilian Collective Action in Civil War : Evidence from the Communist Insurgency in the Philippines
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Rubin, Michael A.
- Published
- 2020
35. Substrate-dependent regiodivergent three-component condensation of 1H-pyrrole-2,3-diones, malononitrile and 4-hydroxyquinolin-2(1H)-ones
- Author
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Salnikova, Tatyana V., Sabitov, Andrey A., Dmitriev, Maksim V., Maslivets, Andrey N., and Rubin, Michael
- Published
- 2021
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36. Variation in Empiric Coverage Versus Detection of Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa in Hospitalizations for Community-Onset Pneumonia Across 128 US Veterans Affairs Medical Centers
- Author
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Jones, Barbara E, Brown, Kevin Antoine, Jones, Makoto M, Huttner, Benedikt D, Greene, Tom, Sauer, Brian C, Madaras-Kelly, Karl, Rubin, Michael A, Goetz, Matthew Bidwell, and Samore, Matthew H
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Infectious Diseases ,Clinical Research ,Lung ,Prevention ,Emerging Infectious Diseases ,Antimicrobial Resistance ,Pneumonia & Influenza ,Pneumonia ,Infection ,Good Health and Well Being ,Aged ,Aged ,80 and over ,Community-Acquired Infections ,Cross Infection ,Hospitalization ,Hospitals ,Veterans ,Humans ,Methicillin Resistance ,Methicillin-Resistant Staphylococcus aureus ,Middle Aged ,Pneumonia ,Bacterial ,Pseudomonas Infections ,United States ,Medical and Health Sciences ,Epidemiology ,Biomedical and clinical sciences ,Health sciences - Abstract
OBJECTIVE To examine variation in antibiotic coverage and detection of resistant pathogens in community-onset pneumonia. DESIGN Cross-sectional study. SETTING A total of 128 hospitals in the Veterans Affairs health system. PARTICIPANTS Hospitalizations with a principal diagnosis of pneumonia from 2009 through 2010. METHODS We examined proportions of hospitalizations with empiric antibiotic coverage for methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa (PAER) and with initial detection in blood or respiratory cultures. We compared lowest- versus highest-decile hospitals, and we estimated adjusted probabilities (AP) for patient- and hospital-level factors predicting coverage and detection using hierarchical regression modeling. RESULTS Among 38,473 hospitalizations, empiric coverage varied widely across hospitals (MRSA lowest vs highest, 8.2% vs 42.0%; PAER lowest vs highest, 13.9% vs 44.4%). Detection rates also varied (MRSA lowest vs highest, 0.5% vs 3.6%; PAER lowest vs highest, 0.6% vs 3.7%). Whereas coverage was greatest among patients with recent hospitalizations (AP for anti-MRSA, 54%; AP for anti-PAER, 59%) and long-term care (AP for anti-MRSA, 60%; AP for anti-PAER, 66%), detection was greatest in patients with a previous history of a positive culture (AP for MRSA, 7.9%; AP for PAER, 11.9%) and in hospitals with a high prevalence of the organism in pneumonia (AP for MRSA, 3.9%; AP for PAER, 3.2%). Low hospital complexity and rural setting were strong negative predictors of coverage but not of detection. CONCLUSIONS Hospitals demonstrated widespread variation in both coverage and detection of MRSA and PAER, but probability of coverage correlated poorly with probability of detection. Factors associated with empiric coverage (eg, healthcare exposure) were different from those associated with detection (eg, microbiology history). Providing microbiology data during empiric antibiotic decision making could better align coverage to risk for resistant pathogens and could promote more judicious use of broad-spectrum antibiotics. Infect Control Hosp Epidemiol 2017;38:937-944.
- Published
- 2017
37. Comparative Effectiveness of Vancomycin and Metronidazole for the Prevention of Recurrence and Death in Patients With Clostridium difficile Infection.
- Author
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Stevens, Vanessa W, Nelson, Richard E, Schwab-Daugherty, Elyse M, Khader, Karim, Jones, Makoto M, Brown, Kevin A, Greene, Tom, Croft, Lindsay D, Neuhauser, Melinda, Glassman, Peter, Goetz, Matthew Bidwell, Samore, Matthew H, and Rubin, Michael A
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Feces ,Humans ,Clostridium Infections ,Metronidazole ,Vancomycin ,Anti-Bacterial Agents ,Treatment Outcome ,Risk Assessment ,Survival Analysis ,Retrospective Studies ,Aged ,Middle Aged ,United States ,Female ,Male ,Secondary Prevention ,Clostridioides difficile ,Clinical Sciences ,Opthalmology and Optometry ,Public Health and Health Services - Abstract
ImportanceMetronidazole hydrochloride has historically been considered first-line therapy for patients with mild to moderate Clostridium difficile infection (CDI) but is inferior to vancomycin hydrochloride for clinical cure. The choice of therapy may likewise have substantial consequences on other downstream outcomes, such as recurrence and mortality, although these secondary outcomes have been less studied.ObjectiveTo evaluate the risk of recurrence and all-cause 30-day mortality among patients receiving metronidazole or vancomycin for the treatment of mild to moderate and severe CDI.Design, setting, and participantsThis retrospective, propensity-matched cohort study evaluated patients treated for CDI, defined as a positive laboratory test result for the presence of C difficile toxins or toxin genes in a stool sample, in the US Department of Veterans Affairs health care system from January 1, 2005, through December 31, 2012. Data analysis was performed from February 7, 2015, through November 22, 2016.ExposuresTreatment with vancomycin or metronidazole.Main outcomes and measuresThe outcomes of interest in this study were CDI recurrence and all-cause 30-day mortality. Recurrence was defined as a second positive laboratory test result within 8 weeks of the initial CDI diagnosis. All-cause 30-day mortality was defined as death from any cause within 30 days of the initial CDI diagnosis.ResultsA total of 47 471 patients (mean [SD] age, 68.8 [13.3] years; 1947 women [4.1%] and 45 524 men [95.9%]) developed CDI, were treated with vancomycin or metronidazole, and met criteria for entry into the study. Of 47 147 eligible first treatment episodes, 2068 (4.4%) were with vancomycin. Those 2068 patients were matched to 8069 patients in the metronidazole group for a total of 10 137 included patients. Subcohorts were constructed that comprised 5452 patients with mild to moderate disease and 3130 patients with severe disease. There were no differences in the risk of recurrence between patients treated with vancomycin vs those treated with metronidazole in any of the disease severity cohorts. Among patients in the any severity cohort, those who were treated with vancomycin were less likely to die (adjusted relative risk, 0.86; 95% CI, 0.74 to 0.98; adjusted risk difference, -0.02; 95% CI, -0.03 to -0.01). No significant difference was found in the risk of mortality between treatment groups among patients with mild to moderate CDI, but vancomycin significantly reduced the risk of all-cause 30-day mortality among patients with severe CDI (adjusted relative risk, 0.79; 95% CI, 0.65 to 0.97; adjusted risk difference, -0.04; 95% CI, -0.07 to -0.01).Conclusions and relevanceRecurrence rates were similar among patients treated with vancomycin and metronidazole. However, the risk of 30-day mortality was significantly reduced among patients who received vancomycin. Our findings may further justify the use of vancomycin as initial therapy for severe CDI.
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- 2017
38. Expanding the use of mathematical modeling in healthcare epidemiology and infection prevention and control
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Grant, Rebecca, Rubin, Michael, Abbas, Mohamed, Pittet, Didier, Srinivasan, Arjun, Jernigan, John A., Bell, Michael, Samore, Matthew, Harbarth, Stephan, and Slayton, Rachel B.
- Abstract
AbstractDuring the coronavirus disease 2019 pandemic, mathematical modeling has been widely used to understand epidemiological burden, trends, and transmission dynamics, to facilitate policy decisions, and, to a lesser extent, to evaluate infection prevention and control (IPC) measures. This review highlights the added value of using conventional epidemiology and modeling approaches to address the complexity of healthcare-associated infections (HAI) and antimicrobial resistance. It demonstrates how epidemiological surveillance data and modeling can be used to infer transmission dynamics in healthcare settings and to forecast healthcare impact, how modeling can be used to improve the validity of interpretation of epidemiological surveillance data, how modeling can be used to estimate the impact of IPC interventions, and how modeling can be used to guide IPC and antimicrobial treatment and stewardship decision-making. There are several priority areas for expanding the use of modeling in healthcare epidemiology and IPC. Importantly, modeling should be viewed as complementary to conventional healthcare epidemiological approaches, and this requires collaboration and active coordination between IPC, healthcare epidemiology, and mathematical modeling groups.
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- 2024
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39. Non-naturalistic moral explanation
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Baron, Samuel, Colyvan, Mark, Miller, Kristie, and Rubin, Michael
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- 2021
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40. Whither Iran? Why the Russia-Iran Alliance Will Backfire
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Rubin, Michael
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Revolutions ,International relations ,Political science ,Regional focus/area studies - Abstract
For all its talk of leading a 'resistance front,' the Islamic Republic of Iran has historically had few allies. When Ayatollah Ruhollah Khomeini led his revolutionaries, 'Neither East nor West [...]
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- 2022
41. Research considerations for prospective studies of patients with coma and disorders of consciousness
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Tinti, L, Lawson, T, Molteni, E, Kondziella, D, Rass, V, Sharshar, T, Bodien, Y, Giacino, J, Mayer, S, Amiri, M, Muehlschlegel, S, Venkatasubba Rao, C, Vespa, P, Menon, D, Citerio, G, Helbok, R, Mcnett, M, Agarwal, S, Aiyagari, V, Akbari, Y, Albertson, A, Alexander, S, Alexandrov, A, Alkhachroum, A, Al-Mufti, F, Appavu, B, Gebrewold, M, Ayounb, M, Badenes, R, Bader, M, Badjiata, N, Balu, R, Barlow, B, Barra, M, Beekman, R, Beghi, E, Beqiri, E, Berlin, T, Bilotta, F, Bleck, T, Boerwinkle, V, Boly, M, Bonnel, A, Brazzi, L, Brown, E, Bulic, S, Caceres, E, Caceres, A, Cafiero, T, Carroll, E, Cediel, E, Chou, S, Claassen, J, Condie, C, Conti, A, Cosmas, K, Costa, P, Creutzfeldt, C, Dangayach, N, Dauri, M, Debicki, D, Degeorgia, M, Der-Nigoghossian, C, Desai, M, Dhar, R, Diringer, M, Durr, E, Edlow, B, Ercole, A, Estraneo, A, Falcone, G, Farrokh, S, Ferguson, A, Fernandez-Espejo, D, Fink, E, Fins, J, Foreman, B, Franchi, F, Frontera, J, Ganesan, R, Gaspard, N, Ghavam, A, Gibbons, C, Gilmore, E, Glustein, C, Gosseries, O, Green, T, Greer, D, Guanci, M, Gupta, D, Hahn, C, Hakimi, R, Hammond, F, Hanley, D, Hartings, J, Hassan, A, Hemphill, C, Da Cunha, A, Hinson, H, Hirsch, K, Hocker, S, Hu, P, Hu, X, Human, T, Hwang, D, Illes, J, Jaffa, M, James, M, Janas, A, Johnson, S, Jones, M, Jox, R, Kalanuria, A, Keller, E, Kennedy, L, Kennelly, M, Keogh, M, Kim, J, Kim, K, Kirsch, H, Kirschen, M, Ko, N, Kreitzer, N, Kromm, J, Kumar, A, Kurtz, P, Laureys, S, Lejeune, N, Lewis, A, Liang, J, Ling, G, Livesay, S, Luppi, A, Macdonald, J, Maddux, C, Mahanes, D, Mainali, S, Maldonado, N, Ribeiro, R, Mascia, L, Massimini, M, Mathur, R, Mccredie, V, Mejia-Mantilla, J, Mendoza, M, Meyfroidt, G, Mijangos, J, Moberg, D, Moheet, A, Montalenti, E, Monti, M, Morrison, C, Munar, M, Murtaugh, B, Naccache, L, Nagayama, M, Nairon, E, Nakagawa, T, Naldi, A, Narenthiran, G, Natarajan, G, Nemetsky, E, Newcombe, V, Nielsen, N, Niznick, N, Noronha-Falcão, F, Nyquist, P, Olson, D, Othman, M, Owen, A, Padayachy, L, Pajoumand, M, Park, S, Pergakis, M, Perry, H, Polizzotto, L, Pouratian, N, Spivack, M, Prisco, L, Provencio, J, Puglises, F, Puybasset, L, Rao, C, Rasmussen, L, Rasulo, F, Ray, B, Ricci, Z, Richardson, R, Shinotsuka, C, Robba, C, Robertson, C, Rohaut, B, Rolston, J, Romagnoli, S, Rosanova, M, Rosenthal, E, Rowe, S, Rubin, M, Russell, M, Silva, G, Sanz, L, Sarasso, S, Sarwal, A, Schiff, N, Schnakers, C, Seder, D, Shah, V, Shapiro-Rosenbaubm, A, Shapshak, A, Sharma, K, Shutter, L, Sitt, J, Slomine, B, Smetana, K, Smielewski, P, Smith, W, Stamatakis, E, Steinberg, A, Stevens, R, Suarez, J, Sung, G, Sussman, B, Taran, S, Mazzeo, A, Thibaut, A, Thompson, D, Threlkeld, Z, Toker, D, Torbey, M, Tosto, J, Trevick, S, Tsaousi, G, Turgeon, A, Udy, A, Varelas, P, Videtta, W, Voss, H, Vox, F, Wagner, A, Wahlster, S, Wainwright, M, Whyte, J, Witherspoon, B, Yakhkind, A, Yeager, S, Young, M, Zafar, S, Zafonte, R, Zahuranec, D, Zammit, C, Zhang, B, Ziai, W, Zimmerman, L, Zink, E, Tinti, Lorenzo, Lawson, Thomas, Molteni, Erika, Kondziella, Daniel, Rass, Verena, Sharshar, Tarek, Bodien, Yelena G, Giacino, Joseph T, Mayer, Stephan A, Amiri, Moshgan, Muehlschlegel, Susanne, Venkatasubba Rao, Chethan P, Vespa, Paul M, Menon, David K, Citerio, Giuseppe, Helbok, Raimund, McNett, Molly, Agarwal, Sachin, Aiyagari, Venkatesh, Akbari, Yama, Albertson, Asher, Alexander, Sheila, Alexandrov, Anne, Alkhachroum, Ayham, Al-Mufti, Fawaz, Amiri, Moshagan, Appavu, Brian, Gebrewold, Meron Awraris, Ayounb, Marc, Badenes, Rafael, Bader, Mary Kay, Badjiata, Neeraj, Balu, Ram, Barlow, Brooke, Barra, Megan, Beekman, Rachel, Beghi, Ettore, Beqiri, Erta, Berlin, Tracey, Bilotta, Federico, Bleck, Thomas, Bodien, Yelena, Boerwinkle, Varina, Boly, Melanie, Bonnel, Alexandra, Brazzi, Luca, Brown, Emery, Bulic, Sebina, Caceres, Eder, Caceres, Adrian, Cafiero, Tullio, Carroll, Elizabeth, Cediel, Emilio G, Chou, Sherry, Claassen, Jan, Condie, Chad, Conti, Alfredo, Cosmas, Katie, Costa, Paolo, Creutzfeldt, Claire, Dangayach, Neha, Dauri, Mario, Debicki, Derek, DeGeorgia, Michael, Der-Nigoghossian, Caroline, Desai, Masoom, Dhar, Rajat, Diringer, Michael, Durr, Emily, Edlow, Brian, Ercole, Ari, Estraneo, Anna, Falcone, Guido, Farrokh, Salia, Ferguson, Adam, Fernandez-Espejo, Davinia, Fink, Ericka, Fins, Joseph, Foreman, Brandon, Franchi, Federico, Frontera, Jennifer, Ganesan, Rishi, Gaspard, Nicolas, Ghavam, Ahmeneh, Giacino, Joseph, Gibbons, Christie, Gilmore, Emily, Glustein, Chavie, Gosseries, Olivia, Green, Theresa, Greer, David, Guanci, Mary, Gupta, Deepak, Hahn, Cecil, Hakimi, Ryan, Hammond, Flora, Hanley, Daniel F, Hartings, Jed, Hassan, Ahmed, Hemphill, Claude, Da Cunha, Arthur Henrique Galvão Bruno, Hinson, Holly, Hirsch, Karen, Hocker, Sarah, Hu, Peter, Hu, Xiao, Human, Theresa, Hwang, David, Illes, Judy, Jaffa, Matthew, James, Michael L, Janas, Anna, Johnson, Susan, Jones, Morgan, Jox, Ralf J, Kalanuria, Atul, Keller, Emanuela, Kennedy, Lori, Kennelly, Megan, Keogh, Maggie, Kim, Jenn, Kim, Keri, Kirsch, Hannah, Kirschen, Matthew, Ko, Nerissa, Kreitzer, Natalie, Kromm, Julie, Kumar, Abhay, Kurtz, Pedro, Laureys, Steven, Lejeune, Nicolas, Lewis, Ariane, Liang, John, Ling, Geoffrey, Livesay, Sarah, Luppi, Andrea, MacDonald, Jennifer, Maddux, Craig, Mahanes, Dea, Mainali, Shraddha, Maldonado, Nelson, Ribeiro, Rennan Martins, Mascia, Luciana, Massimini, Marcello, Mathur, Rohan, Mayer, Stephan, McCredie, Victoria, Mejia-Mantilla, Jorge, Mendoza, Michael, Menon, David, Meyfroidt, Geert, Mijangos, Julio, Moberg, Dick, Moheet, Asma, Montalenti, Elisa, Monti, Martin, Morrison, Chris, Munar, Marina, Murtaugh, Brooke, Naccache, Lionel, Nagayama, Masao, Nairon, Emerson, Nakagawa, Thomas, Naldi, Andrea, Narenthiran, Ganesalingam, Natarajan, Girija, Nemetsky, Esther, Newcombe, Virginia, Nielsen, Niklas, Niznick, Naomi, Noronha-Falcão, Filipa, Nyquist, Paul, Olson, DaiWai, Othman, Marwan, Owen, Adrian, Padayachy, Llewellyn, Pajoumand, Mehrnaz, Park, Soojin, Pergakis, Melissa, Perry, Heidi, Polizzotto, Len, Pouratian, Nader, Spivack, Marilyn Price, Prisco, Lara, Provencio, Javier, Puglises, Francesco, Puybasset, Louis, Rao, Chethan, Rasmussen, Lindsay, Rasulo, Frank, Ray, Bappaditya, Ricci, Zaccaria, Richardson, Risa, Shinotsuka, Cassia Righy, Robba, Chiara, Robertson, Courtney, Rohaut, Benjamin, Rolston, John, Romagnoli, Stefano, Rosanova, Mario, Rosenthal, Eric, Rowe, Shaun, Rubin, Michael, Russell, Mary Beth, Silva, Gisele Sampaio, Sanz, Leandro, Sarasso, Simone, Sarwal, Aarti, Schiff, Nicolas, Schnakers, Caroline, Seder, David, Shah, Vishank Arun, Shapiro-Rosenbaubm, Amy, Shapshak, Angela, Sharma, Kartavya, Sharma, Kumar Ajay, Shutter, Lori, Sitt, Jacobo, Slomine, Beth, Smetana, Keaton, Smielewski, Peter, Smith, Wade, Stamatakis, Emmanuel, Steinberg, Alexis, Stevens, Robert, Suarez, Jose, Sung, Gene, Sussman, Bethany, Taran, Shaurya, Mazzeo, Anna Teresa, Thibaut, Aurore, Thompson, David, Threlkeld, Zachary, Toker, Daniel, Torbey, Michel, Tosto, Jenna, Trevick, Stephen, Tsaousi, Georgia, Turgeon, Alexis, Udy, Andrew, Varelas, Panos, Vespa, Paul, Videtta, Walter, Voss, Henning, Vox, Ford, Wagner, Amy, Wahlster, Sarah, Wainwright, Mark, Whyte, John, Witherspoon, Briana, Yakhkind, Aleksandra (Sasha), Yeager, Susan, Young, Michael, Zafar, Sahar, Zafonte, Ross, Zahuranec, Darin, Zammit, Chris, Zhang, Bei, Ziai, Wendy, Zimmerman, Lara, Zink, Elizabeth, Tinti, L, Lawson, T, Molteni, E, Kondziella, D, Rass, V, Sharshar, T, Bodien, Y, Giacino, J, Mayer, S, Amiri, M, Muehlschlegel, S, Venkatasubba Rao, C, Vespa, P, Menon, D, Citerio, G, Helbok, R, Mcnett, M, Agarwal, S, Aiyagari, V, Akbari, Y, Albertson, A, Alexander, S, Alexandrov, A, Alkhachroum, A, Al-Mufti, F, Appavu, B, Gebrewold, M, Ayounb, M, Badenes, R, Bader, M, Badjiata, N, Balu, R, Barlow, B, Barra, M, Beekman, R, Beghi, E, Beqiri, E, Berlin, T, Bilotta, F, Bleck, T, Boerwinkle, V, Boly, M, Bonnel, A, Brazzi, L, Brown, E, Bulic, S, Caceres, E, Caceres, A, Cafiero, T, Carroll, E, Cediel, E, Chou, S, Claassen, J, Condie, C, Conti, A, Cosmas, K, Costa, P, Creutzfeldt, C, Dangayach, N, Dauri, M, Debicki, D, Degeorgia, M, Der-Nigoghossian, C, Desai, M, Dhar, R, Diringer, M, Durr, E, Edlow, B, Ercole, A, Estraneo, A, Falcone, G, Farrokh, S, Ferguson, A, Fernandez-Espejo, D, Fink, E, Fins, J, Foreman, B, Franchi, F, Frontera, J, Ganesan, R, Gaspard, N, Ghavam, A, Gibbons, C, Gilmore, E, Glustein, C, Gosseries, O, Green, T, Greer, D, Guanci, M, Gupta, D, Hahn, C, Hakimi, R, Hammond, F, Hanley, D, Hartings, J, Hassan, A, Hemphill, C, Da Cunha, A, Hinson, H, Hirsch, K, Hocker, S, Hu, P, Hu, X, Human, T, Hwang, D, Illes, J, Jaffa, M, James, M, Janas, A, Johnson, S, Jones, M, Jox, R, Kalanuria, A, Keller, E, Kennedy, L, Kennelly, M, Keogh, M, Kim, J, Kim, K, Kirsch, H, Kirschen, M, Ko, N, Kreitzer, N, Kromm, J, Kumar, A, Kurtz, P, Laureys, S, Lejeune, N, Lewis, A, Liang, J, Ling, G, Livesay, S, Luppi, A, Macdonald, J, Maddux, C, Mahanes, D, Mainali, S, Maldonado, N, Ribeiro, R, Mascia, L, Massimini, M, Mathur, R, Mccredie, V, Mejia-Mantilla, J, Mendoza, M, Meyfroidt, G, Mijangos, J, Moberg, D, Moheet, A, Montalenti, E, Monti, M, Morrison, C, Munar, M, Murtaugh, B, Naccache, L, Nagayama, M, Nairon, E, Nakagawa, T, Naldi, A, Narenthiran, G, Natarajan, G, Nemetsky, E, Newcombe, V, Nielsen, N, Niznick, N, Noronha-Falcão, F, Nyquist, P, Olson, D, Othman, M, Owen, A, Padayachy, L, Pajoumand, M, Park, S, Pergakis, M, Perry, H, Polizzotto, L, Pouratian, N, Spivack, M, Prisco, L, Provencio, J, Puglises, F, Puybasset, L, Rao, C, Rasmussen, L, Rasulo, F, Ray, B, Ricci, Z, Richardson, R, Shinotsuka, C, Robba, C, Robertson, C, Rohaut, B, Rolston, J, Romagnoli, S, Rosanova, M, Rosenthal, E, Rowe, S, Rubin, M, Russell, M, Silva, G, Sanz, L, Sarasso, S, Sarwal, A, Schiff, N, Schnakers, C, Seder, D, Shah, V, Shapiro-Rosenbaubm, A, Shapshak, A, Sharma, K, Shutter, L, Sitt, J, Slomine, B, Smetana, K, Smielewski, P, Smith, W, Stamatakis, E, Steinberg, A, Stevens, R, Suarez, J, Sung, G, Sussman, B, Taran, S, Mazzeo, A, Thibaut, A, Thompson, D, Threlkeld, Z, Toker, D, Torbey, M, Tosto, J, Trevick, S, Tsaousi, G, Turgeon, A, Udy, A, Varelas, P, Videtta, W, Voss, H, Vox, F, Wagner, A, Wahlster, S, Wainwright, M, Whyte, J, Witherspoon, B, Yakhkind, A, Yeager, S, Young, M, Zafar, S, Zafonte, R, Zahuranec, D, Zammit, C, Zhang, B, Ziai, W, Zimmerman, L, Zink, E, Tinti, Lorenzo, Lawson, Thomas, Molteni, Erika, Kondziella, Daniel, Rass, Verena, Sharshar, Tarek, Bodien, Yelena G, Giacino, Joseph T, Mayer, Stephan A, Amiri, Moshgan, Muehlschlegel, Susanne, Venkatasubba Rao, Chethan P, Vespa, Paul M, Menon, David K, Citerio, Giuseppe, Helbok, Raimund, McNett, Molly, Agarwal, Sachin, Aiyagari, Venkatesh, Akbari, Yama, Albertson, Asher, Alexander, Sheila, Alexandrov, Anne, Alkhachroum, Ayham, Al-Mufti, Fawaz, Amiri, Moshagan, Appavu, Brian, Gebrewold, Meron Awraris, Ayounb, Marc, Badenes, Rafael, Bader, Mary Kay, Badjiata, Neeraj, Balu, Ram, Barlow, Brooke, Barra, Megan, Beekman, Rachel, Beghi, Ettore, Beqiri, Erta, Berlin, Tracey, Bilotta, Federico, Bleck, Thomas, Bodien, Yelena, Boerwinkle, Varina, Boly, Melanie, Bonnel, Alexandra, Brazzi, Luca, Brown, Emery, Bulic, Sebina, Caceres, Eder, Caceres, Adrian, Cafiero, Tullio, Carroll, Elizabeth, Cediel, Emilio G, Chou, Sherry, Claassen, Jan, Condie, Chad, Conti, Alfredo, Cosmas, Katie, Costa, Paolo, Creutzfeldt, Claire, Dangayach, Neha, Dauri, Mario, Debicki, Derek, DeGeorgia, Michael, Der-Nigoghossian, Caroline, Desai, Masoom, Dhar, Rajat, Diringer, Michael, Durr, Emily, Edlow, Brian, Ercole, Ari, Estraneo, Anna, Falcone, Guido, Farrokh, Salia, Ferguson, Adam, Fernandez-Espejo, Davinia, Fink, Ericka, Fins, Joseph, Foreman, Brandon, Franchi, Federico, Frontera, Jennifer, Ganesan, Rishi, Gaspard, Nicolas, Ghavam, Ahmeneh, Giacino, Joseph, Gibbons, Christie, Gilmore, Emily, Glustein, Chavie, Gosseries, Olivia, Green, Theresa, Greer, David, Guanci, Mary, Gupta, Deepak, Hahn, Cecil, Hakimi, Ryan, Hammond, Flora, Hanley, Daniel F, Hartings, Jed, Hassan, Ahmed, Hemphill, Claude, Da Cunha, Arthur Henrique Galvão Bruno, Hinson, Holly, Hirsch, Karen, Hocker, Sarah, Hu, Peter, Hu, Xiao, Human, Theresa, Hwang, David, Illes, Judy, Jaffa, Matthew, James, Michael L, Janas, Anna, Johnson, Susan, Jones, Morgan, Jox, Ralf J, Kalanuria, Atul, Keller, Emanuela, Kennedy, Lori, Kennelly, Megan, Keogh, Maggie, Kim, Jenn, Kim, Keri, Kirsch, Hannah, Kirschen, Matthew, Ko, Nerissa, Kreitzer, Natalie, Kromm, Julie, Kumar, Abhay, Kurtz, Pedro, Laureys, Steven, Lejeune, Nicolas, Lewis, Ariane, Liang, John, Ling, Geoffrey, Livesay, Sarah, Luppi, Andrea, MacDonald, Jennifer, Maddux, Craig, Mahanes, Dea, Mainali, Shraddha, Maldonado, Nelson, Ribeiro, Rennan Martins, Mascia, Luciana, Massimini, Marcello, Mathur, Rohan, Mayer, Stephan, McCredie, Victoria, Mejia-Mantilla, Jorge, Mendoza, Michael, Menon, David, Meyfroidt, Geert, Mijangos, Julio, Moberg, Dick, Moheet, Asma, Montalenti, Elisa, Monti, Martin, Morrison, Chris, Munar, Marina, Murtaugh, Brooke, Naccache, Lionel, Nagayama, Masao, Nairon, Emerson, Nakagawa, Thomas, Naldi, Andrea, Narenthiran, Ganesalingam, Natarajan, Girija, Nemetsky, Esther, Newcombe, Virginia, Nielsen, Niklas, Niznick, Naomi, Noronha-Falcão, Filipa, Nyquist, Paul, Olson, DaiWai, Othman, Marwan, Owen, Adrian, Padayachy, Llewellyn, Pajoumand, Mehrnaz, Park, Soojin, Pergakis, Melissa, Perry, Heidi, Polizzotto, Len, Pouratian, Nader, Spivack, Marilyn Price, Prisco, Lara, Provencio, Javier, Puglises, Francesco, Puybasset, Louis, Rao, Chethan, Rasmussen, Lindsay, Rasulo, Frank, Ray, Bappaditya, Ricci, Zaccaria, Richardson, Risa, Shinotsuka, Cassia Righy, Robba, Chiara, Robertson, Courtney, Rohaut, Benjamin, Rolston, John, Romagnoli, Stefano, Rosanova, Mario, Rosenthal, Eric, Rowe, Shaun, Rubin, Michael, Russell, Mary Beth, Silva, Gisele Sampaio, Sanz, Leandro, Sarasso, Simone, Sarwal, Aarti, Schiff, Nicolas, Schnakers, Caroline, Seder, David, Shah, Vishank Arun, Shapiro-Rosenbaubm, Amy, Shapshak, Angela, Sharma, Kartavya, Sharma, Kumar Ajay, Shutter, Lori, Sitt, Jacobo, Slomine, Beth, Smetana, Keaton, Smielewski, Peter, Smith, Wade, Stamatakis, Emmanuel, Steinberg, Alexis, Stevens, Robert, Suarez, Jose, Sung, Gene, Sussman, Bethany, Taran, Shaurya, Mazzeo, Anna Teresa, Thibaut, Aurore, Thompson, David, Threlkeld, Zachary, Toker, Daniel, Torbey, Michel, Tosto, Jenna, Trevick, Stephen, Tsaousi, Georgia, Turgeon, Alexis, Udy, Andrew, Varelas, Panos, Vespa, Paul, Videtta, Walter, Voss, Henning, Vox, Ford, Wagner, Amy, Wahlster, Sarah, Wainwright, Mark, Whyte, John, Witherspoon, Briana, Yakhkind, Aleksandra (Sasha), Yeager, Susan, Young, Michael, Zafar, Sahar, Zafonte, Ross, Zahuranec, Darin, Zammit, Chris, Zhang, Bei, Ziai, Wendy, Zimmerman, Lara, and Zink, Elizabeth
- Abstract
Disorders of consciousness are neurological conditions characterized by impaired arousal and awareness of self and environment. Behavioural responses are absent or are present but fluctuate. Disorders of consciousness are commonly encountered as a consequence of both acute and chronic brain injuries, yet reliable epidemiological estimates would require inclusive, operational definitions of the concept, as well as wider knowledge dissemination among involved professionals. Whereas several manifestations have been described, including coma, vegetative state/unresponsive wakefulness syndrome and minimally conscious state, a comprehensive neurobiological definition for disorders of consciousness is still lacking. The scientific literature is primarily observational, and studies-specific aetiologies lead to disorders of consciousness. Despite advances in these disease-related forms, there remains uncertainty about whether disorders of consciousness are a disease-agnostic unitary entity with a common mechanism, prognosis or treatment response paradigm. Our knowledge of disorders of consciousness has also been hampered by heterogeneity of study designs, variables, and outcomes, leading to results that are not comparable for evidence synthesis. The different backgrounds of professionals caring for patients with disorders of consciousness and the different goals at different stages of care could partly explain this variability. The Prospective Studies working group of the Neurocritical Care Society Curing Coma Campaign was established to create a platform for observational studies and future clinical trials on disorders of consciousness and coma across the continuum of care. In this narrative review, the author panel presents limitations of prior observational clinical research and outlines practical considerations for future investigations. A narrative review format was selected to ensure that the full breadth of study design considerations could be addressed and to facilit
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- 2024
42. The Neurocritical Care Brain Death Determination Course: Purpose, Design, and Early Findings
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Rubin, Michael A., Kirschen, Mathew P., and Lewis, Ariane
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- 2021
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43. Correction to: Proceedings of the Second Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness
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Mainali, Shraddha, Aiyagari, Venkatesh, Alexander, Sheila, Bodien, Yelena, Boerwinkle, Varina, Boly, Melanie, Brown, Emery, Brown, Jeremy, Claassen, Jan, Edlow, Brian L., Fink, Ericka L., Fins, Joseph J., Foreman, Brandon, Frontera, Jennifer, Geocadin, Romergryko G., Giacino, Joseph, Gilmore, Emily J., Gosseries, Olivia, Hammond, Flora, Helbok, Raimund, Claude Hemphill, J., Hirsch, Karen, Kim, Keri, Laureys, Steven, Lewis, Ariane, Ling, Geoffrey, Livesay, Sarah L., McCredie, Victoria, McNett, Molly, Menon, David, Molteni, Erika, Olson, DaiWai, O’Phelan, Kristine, Park, Soojin, Polizzotto, Len, Javier Provencio, Jose, Puybasset, Louis, Venkatasubba Rao, Chethan P., Robertson, Courtney, Rohaut, Benjamin, Rubin, Michael, Sharshar, Tarek, Shutter, Lori, Sampaio Silva, Gisele, Smith, Wade, Stevens, Robert D., Thibaut, Aurore, Vespa, Paul, Wagner, Amy K., Ziai, Wendy C., Zink, Elizabeth, and Suarez, Jose I.
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- 2022
- Full Text
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44. Doris Duke Charitable Foundation Fund to Retain Clinical Scientists: innovating support for early-career family caregivers
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Jagsi, Reshma, Beeland, T. DeLene, Sia, Kevin, Szczygiel, Lauren A., Allen, Matthew R., Arora, Vineet M., Bair-Merritt, Megan, Bauman, Melissa D., Bogner, Hillary R., Daumit, Gail, Davis, Esa, Fagerlin, Angela, Ford, Daniel E., Gbadegesin, Rasheed, Griendling, Kathy, Hartmann, Katherine, Hedayati, S. Susan, Jackson, Rebecca D., Matulevicius, Susan, Mugavero, Michael J., Nehl, Eric J., Neogi, Tuhina, Regensteiner, Judith G., Rubin, Michael A., Rubio, Doris, Singer, Kanakadurga, Edmonds, Brownsyne Tucker, Volerman, Anna, Laney, Sandra, Patton, Carrie, and Alvarez, Sindy Escobar
- Subjects
Medical scientists -- Finance -- Social aspects ,Caregivers -- Social aspects -- Finance ,Company financing ,Health care industry ,Doris Duke Charitable Foundation -- Donations - Abstract
Introduction The COVID-19 pandemic has highlighted and amplified family caregiving obligations for many clinical investigators and other biomedical researchers. Unpredictable access to daycare, schools, assisted living facilities, informal networks, and [...]
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- 2022
- Full Text
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45. Foreign Sponsorship of Armed Groups and Civil War.
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Rubin, Michael A and Malone, Iris
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CIVIL war , *VIOLENCE - Abstract
Under what conditions do armed groups escalate their campaigns to civil war? Existing research suggests foreign states' material support is critical to explaining armed groups' conduct during civil war and, thereby, war intensification, duration, and outcomes. Thus far, little attention has been paid to understanding whether and how foreign support influences whether armed groups fight civil wars in the first place, largely due to data limitations. Armed group-level datasets have included only those already engaged in significant civil war violence, which introduces selection bias that precludes investigating factors that influence which groups fight civil wars. Leveraging the new Armed Groups Dataset (AGD), which measures characteristics of armed groups engaged in lower-level violence, we conduct a preliminary empirical investigation into the explanatory role of foreign sponsorship in group-level variation in civil war. While foreign sponsorship and civil war are correlated, there is little evidence that sponsorship has substantial independent explanatory value in predicting civil war. Rather, the evidence is consistent with claims that armed groups' organizational characteristics account for both access to foreign sponsorship and, independently, their likelihood of escalating civil war. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
- View/download PDF
46. Coupling the high-temperature Fischer--Tropsch synthesis and the skeletal isomerization reaction at optimal operation conditions in the Power-to-Fuels process route for the production of sustainable aviation gasoline.
- Author
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Dhamo, Dorela, Kühn, Jannis, Lüttin, Simon, Rubin, Michael, and Dittmeyer, Roland
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- 2024
- Full Text
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47. WEATHERING THE CRISIS.
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RAMESH, AKHIL and RUBIN, MICHAEL
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POLITICAL campaigns ,COOPERATION ,POLITICAL parties ,WEATHERING ,CRISES ,HYSTERIA ,BRASS - Abstract
For the US-India bilateral relationship, the first four months of 2024 were a repeat of the last three years: the differences in attitudes toward Cold-War era partnerships resurfaced and made difficult maintaining the calm in bilateral relations. There were significant strides in the economic and trade front. The security relationship, however, was marred by the dispute over the killing of Khalistan separatist, designated as a terrorist by India. Washington diplomatically backed India vis-a-vis China's belligerent actions such as renaming Indian towns by publicly speaking out against it and top military brass made visits to India in a show of support for the growing security cooperation between the two democracies. The election hysteria in India, the heated rhetoric, and polemical statements in the election campaigns of major India political parties provided fodder for the Western press to raise concerns about the supposed "values-based" partnership with India. While not as hyperbolic in nature, US election campaigning dragged India into the mud, with President Biden lumping Japan and India in with Russia and China in a reference to nations that were "xenophobic" and restrictive to immigrants. [ABSTRACT FROM AUTHOR]
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- 2024
48. How Much Does the Family Want to Be Involved in Decision-Making?
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Bryant, Christopher, primary and Rubin, Michael A., additional
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- 2021
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49. 2314. Association Between Behavior and Risk of COVID-19 in a Cohort of Healthcare Personnel
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Shoemaker, Holly, primary, Li, Haojia, additional, Zhang, Yue, additional, Mayer, Jeanmarie, additional, Rubin, Michael, additional, Millar, Morgan M, additional, Gesteland, Per H, additional, Pavia, Andrew T, additional, Keegan, Lindsay T, additional, Braunfeld, Jordan, additional, Stratford, Kristina, additional, and Samore, Matthew H, additional
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- 2023
- Full Text
- View/download PDF
50. Trends in Antibiotic Use and Nosocomial Pathogens in Hospitalized Veterans With Pneumonia at 128 Medical Centers, 2006–2010
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Jones, Barbara E, Jones, Makoto M, Huttner, Benedikt, Stoddard, Gregory, Brown, Kevin Antoine, Stevens, Vanessa W, Greene, Tom, Sauer, Brian, Madaras-Kelly, Karl, Rubin, Michael, Goetz, Matthew Bidwell, and Samore, Matthew
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Emerging Infectious Diseases ,Pneumonia ,Health Services ,Antimicrobial Resistance ,Pneumonia & Influenza ,Clinical Research ,Lung ,Prevention ,Rare Diseases ,Clinical Trials and Supportive Activities ,Infectious Diseases ,Infection ,Acinetobacter ,Aged ,Aged ,80 and over ,Anti-Bacterial Agents ,Cross Infection ,Drug Utilization ,Female ,Hospitalization ,Humans ,Male ,Methicillin-Resistant Staphylococcus aureus ,Middle Aged ,Pneumonia ,Bacterial ,Prevalence ,Pseudomonas aeruginosa ,Veterans ,pneumonia ,antibiotic use ,HCAP ,nosocomial pathogens ,drug-resistant pneumonia ,Biological Sciences ,Medical and Health Sciences ,Microbiology - Abstract
BackgroundIn 2005, pneumonia practice guidelines recommended broad-spectrum antibiotics for patients with risk factors for nosocomial pathogens. The impact of these recommendations on the ability of providers to match treatment with nosocomial pathogens is unknown.MethodsAmong hospitalizations with a principal diagnosis of pneumonia at 128 Department of Veterans Affairs medical centers from 2006 through 2010, we measured annual trends in antibiotic selection; initial blood or respiratory cultures positive for methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, and Acinetobacter species; and alignment between antibiotic coverage and culture results for MRSA and P. aeruginosa, calculating sensitivity, specificity, and diagnostic odds ratio using a 2 × 2 contingency table.ResultsIn 95 511 hospitalizations for pneumonia, initial use of vancomycin increased from 16% in 2006 to 31% in 2010, and piperacillin-tazobactam increased from 16% to 27%, and there was a decrease in both ceftriaxone (from 39% to 33%) and azithromycin (change from 39% to 36%) (P < .001 for all). The proportion of hospitalizations with cultures positive for MRSA decreased (from 2.5% to 2.0%; P < .001); no change was seen for P. aeruginosa (1.9% to 2.0%; P = .14) or Acinetobacter spp. (0.2% to 0.2%; P = .17). For both MRSA and P. aeruginosa, sensitivity increased (from 46% to 65% and 54% to 63%, respectively; P < .001) and specificity decreased (from 85% to 69% and 76% to 68%; P < .001), with no significant changes in diagnostic odds ratio (decreases from 4.6 to 4.1 [P = .57] and 3.7 to 3.2 [P = .95], respectively).ConclusionsBetween 2006 and 2010, we found a substantial increase in the use of broad-spectrum antibiotics for pneumonia despite no increase in nosocomial pathogens. The ability of providers to accurately match antibiotic coverage to nosocomial pathogens remains low.
- Published
- 2015
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