1. Characteristics and Surgical Outcomes in Very Elderly Patients (≥75 years) with Renal Cell Carcinoma: Data from the Latin American Renal Cancer Group
- Author
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Adrián M, Garza-Gangemi, Ricardo A, Castillejos-Molina, Guillermo, Gueglio, Ignacio P, Tobia Gonzalez, Alberto M, Jurado, Luis, Meza-Montoya, Carlos H, Scorticati, Walter, Henriques-da-Costa, Juan, Yandian, Luis, Ubillos, Sidney, Glina, Marcos, Tobias-Machado, Oscar, Rodríguez-Faba, Carlos, Ameri, Alejandro, Nolazco, Pablo, Martinez, Gustavo, Franco-Carvalhal, Ruben G, Bengio, Leandro, Cristian Arribillaga, Raúl, Langenhin, Diego, Muguruza, José G, Campos-Salcedo, Edgar I, Bravo-Castro, Pablo A, Mingote, Nicolás, Ginestar, Ana M, Autran-Gomez, Roberto, Puente, Ricardo, Decia, Gustavo, Cardoso-Guimarães, Joan, Palou-Redorta, Diego, Abreu-Clavijo, Stenio, de-Cassio-Zequi, and Francisco T, Rodriguez-Covarrubias
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Gynecology ,Surgical resection ,medicine.medical_specialty ,business.industry ,Cancer ,General Medicine ,Perioperative ,medicine.disease ,Lower body ,Age groups ,Renal cell carcinoma ,Baseline characteristics ,medicine ,business - Abstract
espanolAntecedentes: la incidencia del carcinoma de celulas renales (CCR) esta aumentando a nivel mundial debido al envejecimiento de la poblacion y al uso generalizado de estudios de imagenes. Objetivo: El objetivo de este estudio fue describir las caracteristicas y resultados perioperatorios de la cirugia de CCR en pacientes muy ancianos (PEV), ≥ 75 anos. Metodos: se trata de un estudio comparativo retrospectivo de 3656 pacientes que se sometieron al tratamiento por CCR entre 1990 y 2015 en 28 centros de ocho paises de America Latina. Comparamos las caracteristicas basales, asi como los resultados clinicos y perioperatorios segun los grupos de edad ( Resultados: Hubo 410 pacientes con PEV (11,2%). En el analisis bivariado, VEP tuvo un indice de masa corporal mas bajo (p 2 en 26.3% vs 12.4%, p estadio pT2 (OR 1,63, p = 0,04) se asociaron de forma independiente con complicaciones perioperatorias. Conclusiones: La reseccion quirurgica del CCR fue segura y exitosa en PEV. La edad ≥75 anos se asocio de forma independiente con complicaciones perioperatorias a los 30 dias. Sin embargo, la gran mayoria fueron complicaciones de bajo grado. La edad por si sola no debe orientar la toma de decisiones en estos pacientes, y el tratamiento debe adaptarse de acuerdo con el estado funcional y la gravedad de las comorbilidades. (REV INVEST CLIN.2020; 72 (5): 308-15) EnglishBackground: The incidence of renal cell carcinoma (RCC) is increasing globally due to an aging population and widespread use of imaging studies. Objective: The aim of this study was to describe the characteristics and perioperative outcomes of RCC surgery in very elderly patients (VEP), ≥ 75 years of age. Methods: This is a retrospective comparative study of 3656 patients who underwent the treatment for RCC from 1990 to 2015 in 28 centers from eight Latin American countries. We compared baseline characteristics as well as clinical and perioperative outcomes according to age groups ( Results: There were 410 VEP patients (11.2%). On bivariate analysis, VEP had a lower body mass index (p 2 in 26.3% vs. 12.4%, p pT2 stage (OR 1.63, p = 0.04) were independently associated with perioperative complications. Conclusions: Surgical resection of RCC was safe and successful in VEP. Age ≥75 years was independently associated with 30-day perioperative complications. However, the vast majority were low-grade complications. Age alone should not guide decision-making in these patients, and treatment must be tailored according to performance status and severity of comorbidities. (REV INVEST CLIN. 2020;72(5):308-15)
- Published
- 2020