10 results on '"Ru Ouyang"'
Search Results
2. Sex Differences in Hypercortisolism and Glucose-Metabolism Disturbances in Patients with Mild Autonomous Cortisol Secretion: Findings From a Single Center in China
- Author
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Ru Ouyang, Yaqi Yin, Jie Wang, Wanlu Su, Li Zang, Kang Chen, Jin Du, Zhaohui Lyu, Jingtao Dou, Yiming Mu, and Weijun Gu
- Subjects
hypercortisolism ,autonomous cortisol secretion ,subclinical Cushing’s disease ,sex differences ,menopausal status ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Background and objectiveMild autonomous cortisol secretion (MACS) presents with a marked female preponderance, but whether the sex difference in its distribution has any relevance to the presentation and outcome of the disease is unknown. The aim of this study was therefore to compare biochemical indices of hypercortisolism and impaired glucose metabolism between male and female patients with MACS.MethodWe enrolled a total of 98 patients with autonomous/possible autonomous cortisol secretion in our study, and indices of hypercortisolism and glucose metabolism were collected and compared between the male and female patients. Logistic regression models were used to evaluate the association between sex and cortisol-secretory ability, as well as between the latter and glucose metabolism. In addition, we conducted further stratified analyses according to the degree of autonomous cortisol secretion and menopausal status.ResultsCortisol levels at 00:00 and 08:00 h after a 1-mg dexamethasone suppression test (DST) and low-dose DST were significantly higher in female than in male MACS patients, and the inhibition rate of 1-mg DST was lower in the women than in the men. This significant difference still remained after adjusting for age, BMI, and the course of the disease. Logistic regression analysis revealed a significant association between autonomous cortisol secretion and fasting C-peptide, as well as with the C-peptide-to-glucose ratio in females relative to male patients. In addition, stratified analyses indicated that this association was observed only among women with autonomous cortisol secretion and who were premenopausal.ConclusionThe level of autonomic cortisol secretion in female patients with MACS was higher than in male patients, and the association between autonomous cortisol secretory ability and glucose homeostasis was only noted in patients with autonomous cortisol secretion and in premenopausal women. This phenomenon will, however, require closer follow-up.
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- 2022
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3. Effect of ultrasound-guided right stellate ganglion block on perioperative atrial fibrillation in patients undergoing lung lobectomy: a randomized controlled trial
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Ru Ouyang, Xinrui Li, Rui Wang, Qiqi Zhou, Yali Sun, and Enjun Lei
- Subjects
Atrial fibrillation ,Lobectomy ,Autonomic function ,Stellate ganglion block ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Objective: To observe the effects of preoperative right stellate ganglion block on perioperative atrial fibrillation in patients undergoing lung lobectomy. Methods: Two hundred patients who underwent a scheduled lobectomy were randomly divided into the S and C groups. The S group was injected with 4 mL of 0.2% ropivacaine under ultrasound guidance, and the C group did not receive stellate ganglion block. The patients underwent continuous ECG monitoring, and the incidences of atrial fibrillation and other types of arrhythmias were recorded from the start of surgery to 24 hours after surgery. Results: The respective incidences of atrial fibrillation in the S group and the C group were 3% and 10% (p = 0.045); other atrial arrhythmias were 20% and 38% (p = 0.005); and ventricular arrhythmia were 28% and 39% (p = 0.09). Conclusions: The results of the study indicated that preoperative right stellate ganglion block can effectively reduce the incidence of intraoperative and postoperative atrial fibrillation.
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- 2020
- Full Text
- View/download PDF
4. Low-intensity transcutaneous auricular vagus nerve stimulation reduces postoperative ileus after laparoscopic radical resection of colorectal cancer: a randomized controlled trial
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RU, Ouyang, primary, JIN, Xianwei, additional, QU, Liangchao, additional, LONG, Dingde, additional, LIU, Mei, additional, CHENG, Liqin, additional, and JIANG, Yao, additional
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- 2023
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5. Study of hsa_circRNA_000121 and hsa_circRNA_004183 in papillary thyroid microcarcinoma
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Chao, Bai, Wenwen, Yang, Ru, Ouyang, Zongbao, Li, and Li, Zhang
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General Immunology and Microbiology ,General Neuroscience ,General Agricultural and Biological Sciences ,General Biochemistry, Genetics and Molecular Biology - Abstract
We detected the expressions of hsa_circRNA_000121 and hsa_circRNA_ 004183 in papillary thyroid microcarcinoma (PTMC) and explored their relationship with the invasiveness of PTMC. PTMC patients with (n = 30; metastasis group) and without lymph node metastasis (n = 30; nonmetastasis group) were included. The levels of hsa_circRNA_000121, hsa_circRNA_004183, hsa-miR-4763, hsa-miR-6775, sarcoma gene (SRC), and MMP-14 were detected with real-time polymerase chain reaction. Receiver-operating characteristic (ROC) analyzed the diagnostic value of hsa_circRNA_000121 and hsa_circRNA_004183. Binary logistic regression analysis evaluated the relationship of gene expression with PTMC invasiveness. In PTMC tissue samples, compared with the metastasis group, the expression of hsa_circRNA_000121, hsa_circRNA_004183, SRC, and MMP-14 in the nonmetastasis group decreased, while the expression of hsa-miR-4763 and hsa-miR-6775 increased. In peripheral blood, compared with the metastasis group, the expression of hsa_circ_000121 and hsa_circRNA_004183 in the nonmetastasis group decreased. Both hsa_circRNA_000121 and hsa_circRNA_004183 had good sensitivity and specificity for diagnosing PTMC lymph node metastasis, with a cut-off value of 0.796 and 0.938, respectively. However, the gene expressions were not significantly associated with PTMC lymph node metastasis. Hsa_circRNA_000121 may upregulate SRC expression through hsa-miR-4763, while hsa_circRNA 000121 may upregulate MMP-14 expression through hsa-miR-6775, thereby promoting the aggressiveness of PTMC and ultimately leading to cervical lymph node metastasis. hsa_circRNA_000121 and hsa_circRNA_004183 may become potential biomarkers of PTMC aggressiveness.
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- 2022
6. Effect of Epalrestat combined with Huoxue Huayu preparation on early diabetic retinopathy and its effect on serum oxidative stress and inflammatory factors
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Ru Ouyang
- Subjects
epalrestat ,therapeutic effect ,inflammatory factors ,early diabetic retinopathy ,lcsh:R ,oxidative stress ,lcsh:Medicine ,blood circulation and blood stasis preparation - Abstract
Objective: To investigate the effect of Epalrestat combined with Huoxue Huayu preparation on early diabetic retinopathy and its effect on serum oxidative stress and inflammatory factors. Methods: 132 patients with early diabetic retinopathy from June 2017 to July 2019 in our hospital were randomly divided into the control group (66 cases) and the observation group (66 cases); The control group was treated with epalrestat, and the observation group was treated with epalrestat combined with ginkgo damo injection; The treatment effect, blood rheology indexes, serum oxidative stress indexes and inflammatory factor indexes of the two groups were compared. Results: The treatment efficiency of the observation group (96.96%) was significantly higher than that of the control group (84.84%) (P
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- 2021
7. Effect of ultrasound-guided right stellate ganglion block on perioperative atrial fibrillation in patients undergoing lung lobectomy: a randomized controlled trial
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Yali Sun, Ru Ouyang, Rui Wang, Enjun Lei, Qiqi Zhou, and Xinrui Li
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Male ,Stellate Ganglion ,law.invention ,lcsh:RD78.3-87.3 ,Electrocardiography ,Lobectomia ,Randomized controlled trial ,Stellate ganglion block ,law ,Anesthesiology ,Monitoring, Intraoperative ,Humans ,Medicine ,In patient ,RD78.3-87.3 ,Lung lobectomy ,cardiovascular diseases ,Função autonômica ,Intraoperative Complications ,Pneumonectomy ,Ultrasonography, Interventional ,Autonomic function ,Aged ,business.industry ,Ropivacaine ,Incidence ,Atrial fibrillation ,General Medicine ,Perioperative ,Middle Aged ,medicine.disease ,Ultrasound guided ,Fibrilação atrial ,Bloqueio do gânglio estrelado ,lcsh:Anesthesiology ,Anesthesia ,cardiovascular system ,Lobectomy ,Female ,business ,Autonomic Nerve Block ,medicine.drug - Abstract
Objective: To observe the effects of preoperative right stellate ganglion block on perioperative atrial fibrillation in patients undergoing lung lobectomy. Methods: Two hundred patients who underwent a scheduled lobectomy were randomly divided into the S and C groups. The S group was injected with 4 mL of 0.2% ropivacaine under ultrasound guidance, and the C group did not receive stellate ganglion block. The patients underwent continuous ECG monitoring, and the incidences of atrial fibrillation and other types of arrhythmias were recorded from the start of surgery to 24 hours after surgery. Results: The respective incidences of atrial fibrillation in the S group and the C group were 3% and 10% (p = 0.045); other atrial arrhythmias were 20% and 38% (p = 0.005); and ventricular arrhythmia were 28% and 39% (p = 0.09). Conclusions: The results of the study indicated that preoperative right stellate ganglion block can effectively reduce the incidence of intraoperative and postoperative atrial fibrillation. Resumo: Objetivo: Observar os efeitos do bloqueio do gânglio estrelado na fibrilação atrial no período perioperatório em pacientes submetidos a lobectomia pulmonar. Método: Duzentos pacientes programados para lobectomia foram divididos aleatoriamente nos grupos S e C. O grupo S recebeu infusão de 4 mL de ropivacaína a 0,2% orientada por ultrasom e o grupo C não foi submetido a bloqueio do gânglio estrelado. Os pacientes foram submetidos à monitoração contínua de ECG, e as incidências de fibrilação atrial e outros tipos de arritmias foram registradas do início da cirurgia até 24 horas depois da cirurgia. Resultados: As incidências de fibrilação atrial no grupo S e no grupo C foram 3% e 10%, respectivamente (p = 0,045); as de outras arritmias atriais foram 20% e 38% (p = 0,005); e de arritmias ventriculares 28% e 39% (p = 0,09). Conclusões: Os resultados do estudo indicaram que o bloqueio do gânglio estrelado no pré-operatório pode ser efetivo na redução da incidência de fibrilação atrial nos períodos intra- e pós-operatório.
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- 2020
8. Efeito do bloqueio do gânglio estrelado direito guiado por ultrassom na fibrilação atrial perioperatória em pacientes submetidos a lobectomia pulmonar: estudo controlado randomizado
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Ru Ouyang, Enjun Lei, Qiqi Zhou, Rui Wang, Yali Sun, and Xinrui Li
- Subjects
03 medical and health sciences ,0302 clinical medicine ,Anesthesiology and Pain Medicine ,030202 anesthesiology - Abstract
Resumo Objetivo Observar os efeitos do bloqueio do gânglio estrelado na fibrilacao atrial no periodo perioperatorio em pacientes submetidos a lobectomia pulmonar. Metodo Duzentos pacientes programados para lobectomia foram divididos aleatoriamente nos grupos S e C. O grupo S recebeu infusao de 4 mL de ropivacaina a 0,2% orientada por ultrassom e o grupo C nao foi submetido a bloqueio do gânglio estrelado. Os pacientes foram submetidos a monitoracao continua de ECG, e as incidencias de fibrilacao atrial e outros tipos de arritmias foram registradas do inicio da cirurgia ate 24 horas depois da cirurgia. Resultados As incidencias de fibrilacao atrial no grupo S e no grupo C foram 3% e 10%, respectivamente (p = 0,045); as de outras arritmias atriais foram 20% e 38% (p = 0,005); e de arritmias ventriculares, 28% e 39% (p = 0,09). Conclusoes Os resultados do estudo indicaram que o bloqueio do gânglio estrelado no pre‐operatorio pode ser efetivo na reducao da incidencia de fibrilacao atrial nos periodos intra‐ e pos‐operatorio.
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- 2020
9. Remifentanil inhibits the traumatic stress response in emergent trauma surgery
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Wei Liu, Ru Ouyang, Xi Yuan, Enjun Lei, and Haijing Ren
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0301 basic medicine ,Male ,Sufentanil ,Clinical Biochemistry ,Hemodynamics ,0302 clinical medicine ,Postoperative Complications ,Immunology and Allergy ,Medicine ,Research Articles ,Traumatic stress ,Hematology ,Middle Aged ,Prognosis ,Analgesics, Opioid ,Medical Laboratory Technology ,Epinephrine ,trauma ,030220 oncology & carcinogenesis ,Female ,Emergency Service, Hospital ,medicine.drug ,Research Article ,Microbiology (medical) ,Adult ,medicine.medical_specialty ,Adolescent ,Remifentanil ,Norepinephrine (medication) ,03 medical and health sciences ,Young Adult ,Stress, Physiological ,Heart rate ,Humans ,emergent surgery protection ,Aged ,business.industry ,Biochemistry (medical) ,Public Health, Environmental and Occupational Health ,stress response ,Surgery ,030104 developmental biology ,Blood pressure ,Wounds and Injuries ,business ,Biomarkers ,Follow-Up Studies - Abstract
Objective The aim of this study was to explore whether remifentanil could inhibit the stress response in emergent trauma surgery more effectively than sufentanil. Patients and methods Sixty trauma patients for emergent surgery were randomly divided into remifentanil group (R group, n = 30) or sufentanil group (S group, n = 30). The patients in the R group were continuously intravenously infused with remifentanil, while those in the S group were administrated with sufentanil. The plasma contents of cortisol (COR), epinephrine (E), norepinephrine (NE), and blood glucose were measured before anesthesia induction (T1), 5 minutes after intratracheal intubation (T2) and 5 minutes (T3), 30 minutes (T4), and 1 hour (T5) after surgery, respectively. The blood pressure (BP) and the heart rate (HR) at these time points were recorded as well. Results The results showed that the patients in the R group had more stable hemodynamics during the surgery and had a significantly lower HR at T2‐T5 than those in the S group. The plasma levels of norepinephrine at time points T3‐T5 and levels of cortisol at T4‐T5 in the R group were significantly lower than those in the S group (P
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- 2019
10. [Epidemiological features of registered cases of pulmonary tuberculosis in urban Guangzhou from 1994 to 2000]
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Jin-ru, Ouyang
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Adult ,Male ,China ,Adolescent ,Infant, Newborn ,Infant ,Middle Aged ,Child, Preschool ,Humans ,Female ,Registries ,Child ,Tuberculosis, Pulmonary ,Aged - Abstract
To understand epidemiological features of pulmonary tuberculosis in urban Giangzhou and tendency of its registered cases.Registered data of pulmonary tuberculosis cases in urban Guangzhou during 1994 to 2000 were collected and analyzed comprehensively with method of descriptive epidemiology.Incidence of recently smear-positive registered rate (IRSPRR) increased from 16.68 per 100,000 in 1994 to 26.27 per 100,000 in 2000, with an average annual increase of 7.86%. The highest standardized IRSPRR was 33.70 per 100,000 in Fangcun District. Average IRSPRR was 30.50 per 100,000 in males and 11.60 per 100,000 in females. IRSPRR increased with age, with a peak of 61.22 per 100,000 at age over 70, double as that at age of 50 - 69. Recently smear-positive registered case of pulmonary tuberculosis was highest in unemployment population, reaching 2529, accounting for 35.12% of the total. And, smear-positive registered rate decreased from 8.37 per 100,000 to 5.34 per 100,000, with an average annual reduction of 6.96%. Mortality of pulmonary tuberculosis decreased from 6.84 per 100,000 to 4.41 per 100,000.It is necessary to keep in minds that highly prevalent area was extended from tuberculous epidemics. It is possible that unemployment people would be fallen into high-risk population. Potential source of infection should be found out as soon as possible.
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- 2004
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