35,439 results on '"Roy S"'
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2. Endoscopic ultrasound with tissue acquisition of lymph nodes in patients with potentially resectable intrahepatic cholangiocarcinoma
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David M. de Jong, Sanne van de Vondervoort, Roy S. Dwarkasing, Maarten G.J. Thomeer, Michael Doukas, Rogier P. Voermans, Robert C. Verdonk, Wojciech G. Polak, Jeroen de Jonge, Marco J. Bruno, Lydi M.J.W. Van Driel, and Bas Groot Koerkamp
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Endoscopic ultrasonography ,Biliary tract ,Tissue diagnosis ,Fine-needle aspiration/biopsy ,GI surgery ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Published
- 2024
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3. Non-contrast short MRI surveillance for HCC screening: the study protocol of the SMS-HCC prospective multicenter study
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Céline van de Braak, François E. J. A. Willemssen, Rob A. de Man, Aad van der Lugt, Carin A. Uyl-de Groot, Daniel Bos, and Roy S. Dwarkasing
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Hepatitis ,Hepatocellular carcinoma ,Liver cirrhosis ,Magnetic resonance imaging ,Ultrasonography ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Abstract Hepatocellular carcinoma (HCC) comprises 75 to 85% of all primary liver cancers. Current guidelines recommend a biannual HCC surveillance using ultrasound (US) for high-risk patients. However, due to its low sensitivity for detection of early-stage HCC lesions, there is an urgency for more sensitive surveillance tools. Here, we describe the potential of a short MRI surveillance (SMS) protocol for HCC, including axial T1-weighted in-out phase, fat-saturated T2-weighted, and diffusion-weighted sequences. In this prospective, multicenter, patient cohort study, patients will be recruited from existing HCC surveillance cohorts of six medical centers in The Netherlands. Surveillance patients who undergo biannual US, will be invited for SMS on the same day for 3 years. In case of a suspicious finding on either US or SMS, patients will be invited for a full MRI liver protocol including gadolinium-based contrast agent intravenous injection within 2 weeks. To our knowledge, this will be the first study to perform a head-to-head comparison with a paired US-MRI design. We hypothesize that the sensitivity of SMS for detection of early-stage HCC will be higher than that of US leading to improved survival of surveillance patients through timely HCC diagnosis. Furthermore, we hypothesize that the SMS-HCC protocol will prove cost-effective. Relevance statement The US sensitivity for detecting early-stage HCC has been reported to be less than 50%. We expect that the proposed SMS will detect at least twice as many early-stage HCC lesions and therefore prove to be cost-effective. Key points • The low sensitivity of US necessitates better imaging tools for HCC screening. • This is the first study with a paired US-MRI design. • This design will allow a head-to-head comparison in both diagnostics and patient-acceptance. • We expect that SMS can contribute to a higher survival rate. Graphical Abstract
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- 2024
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4. Precision needle-punch tumor enrichment from paraffin blocks improves the detection of clinically actionable genomic alterations and biomarkers
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Douglas I. Lin, Richard S. P. Huang, Ioannis Ladas, Rachel B. Keller, Nimesh R. Patel, Sotirios Lakis, Brennan Decker, Tyler Janovitz, Douglas A. Mata, Jeffrey S. Ross, Jo-Anne Vergilio, Julia A. Elvin, Roy S. Herbst, Philip C. Mack, and Jonathan K. Killian
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tumor enrichment ,tumor purity ,biomarker ,molecular diagnosis ,FoundationOne®CDx ,tumor microdissection ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
BackgroundWhile many molecular assays can detect mutations at low tumor purity and variant allele frequencies, complex biomarkers such as tumor mutational burden (TMB), microsatellite instability (MSI), and genomic loss of heterozygosity (gLOH) require higher tumor purity for accurate measurement. Scalable, quality-controlled, tissue-conserving methods to increase tumor nuclei percentage (TN%) from tumor specimens are needed for complex biomarkers and hence necessary to maximize patient matching to approved therapies or clinical trial enrollment. We evaluated the clinical utility and performance of precision needle-punch enrichment (NPE) compared with traditional razor blade macroenrichment of tumor specimens on molecular testing success.MethodsPathologist-directed NPE was performed manually on formalin-fixed, paraffin embedded (FFPE) blocks. Quality control of target capture region and quantity of residual tumor in each tissue block was determined via a post-enrichment histologic slide recut. Resultant tumor purity and biomarker status were determined by the computational analysis pipeline component of the FDA-approved next-generation sequencing (NGS) assay, FoundationOne®CDx. Following NPE implementation for real-world clinical samples, assay performance and biomarker (MSI, TMB, gLOH) detection were analyzed.ResultsIn real-world clinical samples, enrichment rate via NPE was increased to ~50% over a 2.5-year period, exceeding the prior use of razor blade macro-enrichment (
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- 2024
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5. Ambient melting behavior of stoichiometric uranium oxides
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Leonid Burakovsky, Scott D. Ramsey, and Roy S. Baty
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actinide oxides ,uranium oxides ,phase diagram ,quantum molecular dynamics ,density functional theory ,Plasma physics. Ionized gases ,QC717.6-718.8 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
As UO2 is easily oxidized during the nuclear fuel cycle it is important to have a detailed understanding of the structures and properties of the oxidation products. Experimental work over the years has revealed many stable uranium oxides including UO2, U4O9 (UO2.25), U3O7 (UO2.33), U2O5 (UO2.5), U3O8 (UO2.67), and UO3, all with a number of different polymorphs. These oxides are broadly split into two categories, fluorite-based structures with stoichiometries in the range of UO2 to UO2.5 and less dense layered-type structures with stoichiometries in the range of UO2.5 to UO3. While UO2 is well characterized, both experimentally and computationally, there is a paucity of data concerning higher stoichiometry oxides in the literature. In this work we determine the ambient melting points of all the six stoichiometric uranium oxides listed above and compare them to the available experimental and/or theoretical data. We demonstrate that a family of the six ambient melting points map out a solid-liquid transition boundary consistent with the high-temperature portion of the phase diagram of uranium-oxygen system suggested by Babelot et al.
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- 2024
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6. Stable eye versus mouth preference in a live speech-processing task
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Charlotte Viktorsson, Niilo V. Valtakari, Terje Falck-Ytter, Ignace T. C. Hooge, Maja Rudling, and Roy S. Hessels
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Medicine ,Science - Abstract
Abstract Looking at the mouth region is thought to be a useful strategy for speech-perception tasks. The tendency to look at the eyes versus the mouth of another person during speech processing has thus far mainly been studied using screen-based paradigms. In this study, we estimated the eye-mouth-index (EMI) of 38 adult participants in a live setting. Participants were seated across the table from an experimenter, who read sentences out loud for the participant to remember in both a familiar (English) and unfamiliar (Finnish) language. No statistically significant difference in the EMI between the familiar and the unfamiliar languages was observed. Total relative looking time at the mouth also did not predict the number of correctly identified sentences. Instead, we found that the EMI was higher during an instruction phase than during the speech-processing task. Moreover, we observed high intra-individual correlations in the EMI across the languages and different phases of the experiment. We conclude that there are stable individual differences in looking at the eyes versus the mouth of another person. Furthermore, this behavior appears to be flexible and dependent on the requirements of the situation (speech processing or not).
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- 2023
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7. Short-Term Treatment Outcomes of Brolucizumab in Patients with Neovascular Age-Related Macular Degeneration: A Multicentre Indian Real-World Evidence Study
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Chakraborty D, Thakkar M, Venkatesh R, Roy S, Bhavsar M, and Karcher H
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anti-vegf ,brolucizumab ,namd ,real-world evidence ,india ,Ophthalmology ,RE1-994 - Abstract
Debdulal Chakraborty,1 Milan Thakkar,2 Ramesh Venkatesh,3 Sangeeta Roy,4 Maulik Bhavsar,5 Helene Karcher6 1Disha Eye Hospital, Kolkata, West Bengal, India; 2Dr. Milan’s Retina Care Centre, Rajkot, Gujarat, India; 3Narayana Nethralaya, Bangalore, Karnataka, India; 4Susrut Eye Foundation and Research Centre, Kolkata, West Bengal, India; 5Novartis Healthcare Pvt. Ltd., Mumbai, Maharashtra, India; 6Novartis Pharma AG, Basel, SwitzerlandCorrespondence: Debdulal Chakraborty, Disha Eye Hospital, Kolkata, West Bengal, India, Email devdc@rediffmail.comObjective: To evaluate the short-term effectiveness and safety outcomes following brolucizumab treatment in patients with neovascular age-related macular degeneration (nAMD) as a part of real-world clinical practice in India.Methods: This was a retrospective, observational, multicentre study including patients (≥ 50 years old) diagnosed with nAMD. Anonymized data of the patients receiving the first dose of brolucizumab intravitreal injection (IVI) who were either treatment-naïve or previously treated with a single or a combination of other anti-VEGF IVIs were included. The present study reported the change in retinal fluid levels from baseline to month 3, best-corrected visual acuity (BCVA), central retinal thickness (CRT), and the number of injections received. The adverse events in the three months after brolucizumab treatment initiation were also monitored.Results: The study included 63 patients (65 eyes) from four study centres across India (mean age: 69.1 ± 9.7 years). A total of 82 brolucizumab injections were administered during the 3 months of study duration, with 52/65 (80.0%) eyes receiving only 1 injection. Resolution of IRF, SRF, and PED was observed in 76.9%, 64.6%, and 67.7% of eyes, respectively. Further, a significant reduction in CRT was observed (baseline: 403.5 ± 118.7 μm; month 3: 308.3 ± 73.8 μm; p < 0.001), and BCVA also improved notably from 0.7 ± 0.5 logMAR at baseline to 0.5 ± 0.4 logMAR at month 3 (p < 0.001). Adverse events (AEs) were reported in 3 eyes from 3 patients; retinal pigment epithelial rip (1) and subretinal hemorrhage (2) after the first injection of brolucizumab, however, none discontinued the treatment.Conclusion: The study reports on the short-term effectiveness and tolerability of brolucizumab therapy in the management of nAMD in both treatment-naïve and switch eyes. Brolucizumab was observed to have a favourable benefit-risk profile, and study results were within the known safety profile, with no instances of intraocular inflammation.Keywords: anti-VEGF, brolucizumab, nAMD, real-world evidence, India
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- 2023
8. Frameworks for estimating causal effects in observational settings: comparing confounder adjustment and instrumental variables
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Roy S. Zawadzki, Joshua D. Grill, Daniel L. Gillen, and and for the Alzheimer’s Disease Neuroimaging Initiative
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Causal inference ,Observational studies ,Instrumental variables ,Adjustment ,Propensity scores ,Medicine (General) ,R5-920 - Abstract
Abstract To estimate causal effects, analysts performing observational studies in health settings utilize several strategies to mitigate bias due to confounding by indication. There are two broad classes of approaches for these purposes: use of confounders and instrumental variables (IVs). Because such approaches are largely characterized by untestable assumptions, analysts must operate under an indefinite paradigm that these methods will work imperfectly. In this tutorial, we formalize a set of general principles and heuristics for estimating causal effects in the two approaches when the assumptions are potentially violated. This crucially requires reframing the process of observational studies as hypothesizing potential scenarios where the estimates from one approach are less inconsistent than the other. While most of our discussion of methodology centers around the linear setting, we touch upon complexities in non-linear settings and flexible procedures such as target minimum loss-based estimation and double machine learning. To demonstrate the application of our principles, we investigate the use of donepezil off-label for mild cognitive impairment. We compare and contrast results from confounder and IV methods, traditional and flexible, within our analysis and to a similar observational study and clinical trial.
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- 2023
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9. 1103 Spatial mapping and clinical significance of the CD39/CD73 adenosinergic pathway as a candidate immunotherapy target in non-small cell lung cancer
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Rakesh Kumar, Roy S Herbst, Sarah Goldberg, Zachary A Cooper, Kurt Schalper, Kerryan Ashley, and Krishna Iyer
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2023
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10. 606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy
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Robert Johnston, Hartmut Koeppen, Roy S Herbst, Kurt Schalper, Filippo De Marinis, Giuseppe Giaccone, Jacek Jassem, Marcus Ballinger, Barani Kumar Rajendran, David R Spigel, Miguel López de Rodas, Minu K Srivastava, Jennifer M Giltnane, Barzin Y Nabet, David S Shames, Velimir Gayevskiy, Vy Ma, Ivette Estay, Tien Hoang, and Reena Amin
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2023
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11. 1102 The HLA-E/NKG2A axis is a dominant immunomodulatory pathway associated with distinct tumor microenvironment features in a subset of NSCLC
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Rakesh Kumar, Roy S Herbst, Sarah Goldberg, Zachary A Cooper, Kurt Schalper, Kerryan Ashley, and Krishna Iyer
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2023
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12. Success in Increasing Diversity: One Residency Program's Journey
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Jamie B. Rosenberg, Sunju Park, Richard Gibralter, Anurag Shrivastava, and Roy S. Chuck
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Ophthalmology ,RE1-994 - Published
- 2023
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13. Shock standards Cu, Ag, Ir, and Pt in a wide pressure range
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Leonid Burakovsky, Dean L. Preston, Scott D. Ramsey, Charles E. Starrett, and Roy S. Baty
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Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Although they are polymorphic (multiphase) materials, both copper and silver are reliable Hugoniot standards, and thus it is necessary to establish an accurate analytic model of their principal Hugoniots. Here we present analytic forms of their principal Hugoniots, as well as those of iridium and platinum, two “pusher” standards for shock-ramp experiments, over a wide range of pressures. They are based on our new analytic model of the principal Hugoniot [Burakovsky et al., J. Appl. Phys. 132, 215109 (2022)]. Comparison of the four Hugoniots with experimental and independent theoretical data (such data exist to very high pressures for both copper and silver) demonstrates excellent agreement. Hence, the new model for copper and silver can be considered as providing the corresponding Hugoniot standards over a wide pressure range. We also suggest an approach for calculating the Grüneisen parameter along the Hugoniot and apply it to copper as a prototype, and our results appear to be in good agreement with the available data.
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- 2023
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14. Development and evaluation of a novel dietary bisphenol A (BPA) exposure risk tool
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Jennifer C. Hartle, Roy S. Zawadzki, Joseph Rigdon, Juleen Lam, and Christopher D. Gardner
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Bisphenol A ,Food packaging ,Environmental phenols ,Diet ,Exposure ,Risk ,Nutrition. Foods and food supply ,TX341-641 ,Food processing and manufacture ,TP368-456 ,Medicine (General) ,R5-920 - Abstract
Abstract Background Exposure to endocrine disrupting chemicals such as bisphenol A (BPA) is primarily from the diet through canned foods. Characterizing dietary exposures can be conducted through biomonitoring and dietary surveys; however, these methods can be time-consuming and challenging to implement. Methods We developed a novel dietary exposure risk questionnaire to evaluate BPA exposure and compared these results to 24-hr dietary recall data from participants (n = 404) of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) study, a dietary clinical trial, to validate questionnaire responses. High BPA exposure foods were identified from the dietary recalls and used to estimate BPA exposure. Linear regression models estimated the association between exposure to BPA and questionnaire responses. A composite risk score was developed to summarize questionnaire responses. Results In questionnaire data, 65% of participants ate canned food every week. A composite exposure score validated that the dietary exposure risk questionnaire captured increasing BPA exposure. In the linear regression models, utilizing questionnaire responses vs. 24-hr dietary recall data, participants eating canned foods 1–2 times/week (vs. never) consumed 0.78 more servings (p
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- 2022
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15. The effect of natural convection air temperature on the drying kinetics and desorption isotherms of Alaria esculenta and Palmaria palmata
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Roy S. Bartle and Alasdair Macleod
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convective blown air drying ,desorption isotherms ,drying kinetics ,heat of sorption ,Aquaculture. Fisheries. Angling ,SH1-691 ,Environmental sciences ,GE1-350 - Abstract
The Northern Periphery and Arctic region faces unique economic and food security challenges that may be partly answered by commercial seaweed production. Alaria esculenta and Palmaria palmata are two seaweeds commonly found in the region and suitable for cultivation and processing for food and other commercial products. The drying kinetics for both species were obtained, and the Page and Weibull models best described the data. A drying air temperature increase from 40 to 70°C decreased drying time by 62.4% and 61.7% for A. esculenta and P. palmata, respectively. Desorption isotherms were obtained between 25 and 70°C and showed Brunauer Category III shapes, with water activity increasing with temperature for a fixed moisture content. Net heats of desorption were obtained, with drying to an equilibrium moisture content of 0.01 kgwater kgd.b.–1 requiring 18.1 and 3.94 kJ mol–1 K–1 for A. esculenta and P. palmata, respectively.
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- 2022
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16. Surgical Complication Risk Factor Identification Using High-Dimensional Hospital Data: An Illustrative Example in Hemostasis-Related Complications
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Johnston S, Jha A, Roy S, and Pollack E
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hemostasis ,high-dimensional ,real-world data ,surgery ,complications ,Medicine (General) ,R5-920 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Stephen Johnston,1 Aakash Jha,2 Sanjoy Roy,3 Esther Pollack3 1MedTech Epidemiology and Real-World Data Sciences; Johnson & Johnson, New Brunswick, NJ, USA; 2Decision Science, Mu Sigma, Bangalore, India; 3Ethicon, Cincinnati, OH, USACorrespondence: Stephen Johnston, MedTech Epidemiology and Real-World Data Sciences, Johnson & Johnson, 410 George Street, New Brunswick, NJ, 08901, USA, Tel +1-443-254-2222, Email sjohn147@its.jnj.comPurpose: To describe an approach wherein high-dimensional hospital data can be used to identify generalizable risk factors for surgical complications for which there may be limited prior knowledge, as illustrated in the context of hemostasis-related complications (HRC).Patients and Methods: This was a retrospective study of the Premier Healthcare Database. Patients included for the study underwent video-assisted thoracoscopic lobectomy (VATL), laparoscopic right colectomy (LRC), or laparoscopic sleeve gastrectomy (LSG) on an inpatient setting between Oct-2015 and Feb-2020 (first = index). The outcome, HRC, comprised hemorrhage, control of bleeding, and acute posthemorrhagic anemia. For each cohort, a high-dimensional dataset (ie, comprising 1000s of candidate risk factors) was constructed using taxonomies from the Clinical Classification Software Refined (CCSR). Candidate risk factors were fed into logistic regression models with a 70%/30% train/test split for each cohort; clinically plausible risk factors that were consistently significant predictors of HRC across the 3 training models were then used in a final parsimonious model including sex, age, race, and payor; finally, the parsimonious model was applied to the test data to compare predicted risk with observed incidence of HRSC.Results: The study included 11,141 VATL, 20,156 LRC, and 121,547 LSG patients, in whom 7.5%, 7.8%, and 1.2% experienced HRSC, respectively. Ultimately, 6 clinically plausible CCSR categories were identified as being statistically significant predictors across all 3 cohorts (eg, coagulation and hemorrhagic disorders, malnutrition, alcohol-related disorders, among others). In the parsimonious model applied to the test data, the observed incidence of HRSC was substantially higher in the top quintile vs bottom quintile of predicted risk: LSG 2.05% vs 0.53%, LRC 13.30% vs 4.11%, VATS 12.49% vs 5.04%.Conclusion: High-dimensional real-world data can be useful to identify risk factors for outcomes that generalize across multiple cohorts. The risk factors identified herein should be considered for inclusion in future studies of hemostasis-related complications.Keywords: hemostasis, high-dimensional, real-world data, surgery, complications
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- 2022
17. Retrospective Comparison of Clinical and Economic Outcomes of Non-Donor Patients Undergoing Radical Nephrectomy Using One of Two Different Linear Stapler Technologies for Transection of the Renal Vessels: Fixed-Height Gripping Surface Reloads vs Variable-Height Reloads
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Johnston SS, Johnson BH, Chakke D, Roy S, Grange P, and Pollack E
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radical nephrectomy ,hemostasis-related complications ,endoscopic surgical staplers ,healthcare utilization ,Medical technology ,R855-855.5 - Abstract
Stephen S Johnston,1 Barbara H Johnson,1 Divya Chakke,2 Sanjoy Roy,3 Philippe Grange,4 Esther Pollack3 1MedTech Epidemiology and Real-World Data Sciences, Johnson & Johnson, New Brunswick, NJ, USA; 2Analytics, Mu Sigma, Bangalore, India; 3Franchise Health Economics and Market Access, Johnson & Johnson, Raritan, NJ, USA; 4Medical, Johnson & Johnson, Cincinnati, OH, USACorrespondence: Stephen S Johnston, Real-World Data Analytics and Research, MedTech Epidemiology and Real-World Data Sciences, Johnson & Johnson, 410 George Street, New Brunswick, NJ, USA, Tel +1-443-254-2222, Email sjohn147@its.jnj.comPurpose: To compare outcomes of non-donor patients undergoing radical nephrectomy using fixed-height gripping surface (FHGS) vs variable-height Tri-Staple™ (VHTS) reloads for transection of the renal vessels.Patients and Methods: Using the Premier Healthcare Database of US hospital discharge records, we selected non-donor patients undergoing inpatient radical nephrectomy with dates of admission between 1 October 2015, and 31 December 2020 (first=index admission). The primary outcome was in-hospital hemostasis-related complications (hemorrhage, acute posthemorrhagic anemia, and/or procedure to control bleeding) during the index admission. Secondary outcomes included index admission intraoperative injury, blood transfusion, conversion from minimally invasive to open surgery, total hospital costs, length of stay (LOS), discharge status, and mortality as well as 30-day all-cause inpatient readmission. We used stable balancing weights to balance the FHGS and VHTS groups on numerous patient, procedure, and hospital/provider characteristics, allowing a maximum post-weighting standardized mean difference ≤ 0.01 for all covariates; we also exactly matched the groups on laterality (right vs left kidney) and intended surgical approach (open, laparoscopic, robotic). We used bivariate multilevel mixed-effects generalized linear models accounting for hospital-level clustering to compare the study outcomes between the FHGS and VHTS groups.Results: After weighting, the FHGS and VHTS groups comprised 2952 and 795 patients, respectively. The observed incidence proportion of the primary outcome of hemostasis-related complications during the index admission was similar between the groups (8.6% for FHGS vs 9.0% for VHTS, difference 0.4% [95% CI − 3.2% to 2.5%], P=0.808). Differences between the FHGS and VHTS groups were not statistically significant for any of the secondary outcomes.Conclusion: Endoscopic surgical staplers have become common for transection of the renal vessels during radical nephrectomy, with FHGS and VHTS being the predominant reload types. In this retrospective study of 3747 non-donor patients undergoing radical nephrectomy, use of FHGS vs VHTS reloads was associated with similar clinical and economic outcomes.Keywords: radical nephrectomy, hemostasis-related complications, endoscopic surgical staplers, healthcare utilization
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- 2022
18. Increasing electrical reserve provision in districts by exploiting energy flexibility of buildings with robust model predictive control
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Felix Bünning, Philipp Heer, Roy S. Smith, and John Lygeros
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Frequency regulation ,Robust Model Predictive Control ,Demand forecasting ,Building energy ,District heating ,Affine policies ,Energy industries. Energy policy. Fuel trade ,HD9502-9502.5 - Abstract
Due to their thermal inertia, buildings equipped with electric heating and cooling systems can help to stabilize the electricity grid by shifting their load in time, and can thus facilitate energy flexible urban energy systems with the right control system in place. Because of minimum capacity requirements, they can often only participate in demand response schemes, such as secondary frequency reserves through aggregation. Such an aggregation could also take the form of entire district heating and cooling systems with connected buildings that are supplied by large-scale heat pumps and chillers. However, there is a lack of studies investigating the control of such configurations, both in simulation and in application. We present a two-level control scheme based on robust Model Predictive Control with affine policies to offer frequency reserves with a district system, where we exploit the thermal inertia of buffer storage tanks and a subset of the connected buildings. We leverage data-driven model generation methods to overcome the bottleneck of physics-based building modeling. In a numerical case study based on one-year historical data of a real system, we compare the approach to a situation where only the buffer storage is used for flexibility and demonstrate that the reserves offered increase substantially if the inertia of a subset of the connected buildings is also exploited. Furthermore, we validate the control approach in a first-of-its-kind experiment on the actual system, where we show that reserves can be offered by the district system without compromising the comfort in the connected buildings.
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- 2023
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19. Modeling and control of a photovoltaic-wind hybrid microgrid system using GA-ANFIS
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Linus A. Aloo, Peter K. Kihato, Stanley I. Kamau, and Roy S. Orenge
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BESS ,GA-ANFIS ,Perturb and observe (P&O) ,Photovoltaic ,PV-Wind hybrid model ,Science (General) ,Q1-390 ,Social sciences (General) ,H1-99 - Abstract
This paper aims to model a PV-Wind hybrid microgrid that incorporates a Battery Energy Storage System (BESS) and design a Genetic Algorithm-Adaptive Neuro-Fuzzy Inference System (GA-ANFIS) controller to regulate its voltage amid power generation variations. Two microgrid models have been developed; a scalable Simulink Case Study Model from underlying mathematical equations and a nested voltage-current loop-based Transfer Function model. The proposed GA-ANFIS controller has been used as a Maximum Power Point Tracking (MPPT) algorithm to optimize the converter outputs and provide voltage regulation. The performance of the GA-ANFIS algorithm was compared with the Search Space Restricted-Perturb and Observe (SSR-P&O) and the Proportional-plus-Integral-plus-Derivative (PID) controllers using a simulation model built in MATLAB/SIMULINK. Results indicated that the GA-ANFIS controller is superior to the SSR-P&O and PID in terms of reduced rise time, settling time, overshoot, and the ability to handle non-linearities in the microgrid. In future work, the GA-ANFIS microgrid control system can be replaced with a three-term hybrid artificial intelligence algorithms controller.
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- 2023
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20. Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
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Raman, Gayathri, Ronchini, Samuele, Delaunay, James, Tohuvavohu, Aaron, Kennea, Jamie A., Parsotan, Tyler, Ambrosi, Elena, Bernardini, Maria Grazia, Campana, Sergio, Cusumano, Giancarlo, D'Ai, Antonino, D'Avanzo, Paolo, D'Elia, Valerio, De Pasquale, Massimiliano, Dichiara, Simone, Evans, Phil, Hartmann, Dieter, Kuin, Paul, Melandri, Andrea, O'Brien, Paul, Osborne, Julian P., Page, Kim, Palmer, David M., Sbarufatti, Boris, Tagliaferri, Gianpiero, Troja, Eleonora, Abac, A. G., Abbott, R., Abe, H., Abouelfettouh, I., Acernese, F., Ackley, K., Adamcewicz, C., Adhicary, S., Adhikari, N., Adhikari, R. X., Adkins, V. K., Adya, V. B., Affeldt, C., Agarwal, D., Agathos, M., Aguiar, O. D., Aguilar, I., Aiello, L., Ain, A., Akutsu, T., Albanesi, S., Alfaidi, R. A., Al-Jodah, A., Alléné, C., Allocca, A., Al-Shammari, S., Altin, P. A., Alvarez-Lopez, S., Amato, A., Amez-Droz, L., Amorosi, A., Amra, C., Anand, S., Ananyeva, A., Anderson, S. B., Anderson, W. G., Andia, M., Ando, M., Andrade, T., Andres, N., Andrés-Carcasona, M., Andrić, T., Anglin, J., Ansoldi, S., Antelis, J. M., Antier, S., Aoumi, M., Appavuravther, E. Z., Appert, S., Apple, S. K., Arai, K., Araya, A., Araya, M. C., Areeda, J. S., Aritomi, N., Armato, F., Arnaud, N., Arogeti, M., Aronson, S. M., Ashton, G., Aso, Y., Assiduo, M., Melo, S. Assis de Souza, Aston, S. M., Astone, P., Aubin, F., AultONeal, K., Avallone, G., Babak, S., Badaracco, F., Badger, C., Bae, S., Bagnasco, S., Bagui, E., Bai, Y., Baier, J. G., Bajpai, R., Baka, T., Ball, M., Ballardin, G., Ballmer, S. W., Banagiri, S., Banerjee, B., Bankar, D., Baral, P., Barayoga, J. C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Barthelmy, S. D., Barton, M. A., Bartos, I., Basak, S., Basalaev, A., Bassiri, R., Basti, A., Bawaj, M., Baxi, P., Bayley, J. C., Baylor, A. C., Bazzan, M., Bécsy, B., Bedakihale, V. 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A., Prokhorov, L., Prosposito, P., Prudenzi, L., Puecher, A., Pullin, J., Punturo, M., Puosi, F., Puppo, P., Pürrer, M., Qi, H., Qin, J., Quéméner, G., Quetschke, V., Quigley, C., Quinonez, P. J., Quitzow-James, R., Raab, F. J., Raaijmakers, G., Radulesco, N., Raffai, P., Rail, S. X., Raja, S., Rajan, C., Rajbhandari, B., Ramirez, D. S., Ramirez, K. E., Vidal, F. A. Ramis, Ramos-Buades, A., Rana, D., Randel, E., Ranjan, S., Rapagnani, P., Ratto, B., Rawat, S., Ray, A., Raymond, V., Razzano, M., Read, J., Payo, M. Recaman, Regimbau, T., Rei, L., Reid, S., Reid, S. W., Reitze, D. H., Relton, P., Renzini, A., Rettegno, P., Revenu, B., Reza, A., Rezac, M., Rezaei, A. S., Ricci, F., Ricci, M., Richards, D., Richardson, C. J., Richardson, J. W., Rijal, A., Riles, K., Riley, H. K., Rinaldi, S., Rittmeyer, J., Robertson, C., Robinet, F., Robinson, M., Rocchi, A., Rolland, L., Rollins, J. G., Romanelli, M., Romano, A. E., Romano, R., Romero, A., Romero-Shaw, I. M., Romie, J. H., Roocke, T. J., Rosa, L., Rosauer, T. J., Rose, C. A., Rosińska, D., Ross, M. P., Rossello, M., Rowan, S., Roy, S. K., Roy, S., Rozza, D., Ruggi, P., Morales, E. Ruiz, Ruiz-Rocha, K., Sachdev, S., Sadecki, T., Sadiq, J., Saffarieh, P., Sah, M. R., Saha, S. S., Sainrat, T., Menon, S. Sajith, Sakai, K., Sakellariadou, M., Sako, T., Sakon, S., Salafia, O. S., Salces-Carcoba, F., Salconi, L., Saleem, M., Salemi, F., Sallé, M., Salvador, S., Sanchez, A., Sanchez, E. J., Sanchez, J. H., Sanchez, L. E., Sanchis-Gual, N., Sanders, J. R., Sänger, E. M., Saravanan, T. R., Sarin, N., Sasli, A., Sassi, P., Sassolas, B., Satari, H., Sato, R., Sato, S., Sato, Y., Sauter, O., Savage, R. L., Sawada, T., Sawant, H. L., Sayah, S., Schaetzl, D., Scheel, M., Scheuer, J., Schiworski, M. G., Schmidt, P., Schmidt, S., Schnabel, R., Schneewind, M., Schofield, R. M. S., Schouteden, K., Schuler, H., Schulte, B. W., Schutz, B. F., Schwartz, E., Scott, J., Scott, S. M., Seetharamu, T. C., Seglar-Arroyo, M., Sekiguchi, Y., Sellers, D., Sengupta, A. S., Sentenac, D., Seo, E. G., Seo, J. W., Sequino, V., Sergeev, A., Serra, M., Servignat, G., Setyawati, Y., Shaffer, T., Shah, U. S., Shahriar, M. S., Shaikh, M. A., Shams, B., Shao, L., Sharma, A. K., Sharma, P., Sharma-Chaudhary, S., Shawhan, P., Shcheblanov, N. S., Shen, B., Shikano, Y., Shikauchi, M., Shimode, K., Shinkai, H., Shiota, J., Shoemaker, D. H., Shoemaker, D. M., Short, R. W., ShyamSundar, S., Sider, A., Siegel, H., Sieniawska, M., Sigg, D., Silenzi, L., Simmonds, M., Singer, L. P., Singh, A., Singh, D., Singh, M. K., Singha, A., Sintes, A. M., Sipala, V., Skliris, V., Slagmolen, B. J. J., Slaven-Blair, T. J., Smetana, J., Smith, J. R., Smith, L., Smith, R. J. E., Smith, W. J., Soldateschi, J., Somala, S. N., Somiya, K., Soni, K., Soni, S., Sordini, V., Sorrentino, F., Sorrentino, N., Soulard, R., Souradeep, T., Southgate, A., Sowell, E., Spagnuolo, V., Spencer, A. P., Spera, M., Spinicelli, P., Srivastava, A. K., Stachurski, F., Steer, D. A., Steinlechner, J., Steinlechner, S., Stergioulas, N., Stevens, P., StPierre, M., Strang, L. C., Stratta, G., Strong, M. D., Strunk, A., Sturani, R., Stuver, A. L., Suchenek, M., Sudhagar, S., Sueltmann, N., Sullivan, A. G., Sullivan, K. D., Sun, L., Sunil, S., Sur, A., Suresh, J., Sutton, P. J., Suzuki, Takamasa, Suzuki, Takanori, Swinkels, B. L., Syx, A., Szczepańczyk, M. J., Szewczyk, P., Tacca, M., Tagoshi, H., Tait, S. C., Takahashi, H., Takahashi, R., Takamori, A., Takatani, K., Takeda, H., Takeda, M., Talbot, C. J., Talbot, C., Tamaki, M., Tamanini, N., Tanabe, D., Tanaka, K., Tanaka, S. J., Tanaka, T., Tanasijczuk, A. J., Tang, D., Tanioka, S., Tanner, D. B., Tao, L., Tapia, R. D., Martín, E. N. Tapia San, Tarafder, R., Taranto, C., Taruya, A., Tasson, J. D., Teloi, M., Tenorio, R., Themann, H., Theodoropoulos, A., Thirugnanasambandam, M. P., Thomas, L. M., Thomas, M., Thomas, P., Thompson, J. E., Thondapu, S. R., Thorne, K. A., Thrane, E., Tissino, J., Tiwari, A., Tiwari, Shubhanshu, Tiwari, Srishti, Tiwari, V., Todd, M. R., Toivonen, A. M., Toland, K., Tolley, A. E., Tomaru, T., Tomita, K., Tomura, T., Tong-Yu, C., Toriyama, A., Toropov, N., Torres-Forné, A., Torrie, C. I., Toscani, M., Melo, I. Tosta e, Tournefier, E., Trani, A. A., Trapananti, A., Travasso, F., Traylor, G., Trenado, J., Trevor, M., Tringali, M. C., Tripathee, A., Troiano, L., Trovato, A., Trozzo, L., Trudeau, R. J., Tsang, T. T. L., Tso, R., Tsuchida, S., Tsukada, L., Tsutsui, T., Turbang, K., Turconi, M., Turski, C., Ubach, H., Ubhi, A. S., Uchikata, N., Uchiyama, T., Udall, R. P., Uehara, T., Ueno, K., Unnikrishnan, C. S., Ushiba, T., Utina, A., Vacatello, M., Vahlbruch, H., Vaidya, N., Vajente, G., Vajpeyi, A., Valdes, G., Valencia, J., Valentini, M., Vallejo-Peña, S. A., Vallero, S., Valsan, V., van Bakel, N., van Beuzekom, M., van Dael, M., Brand, J. F. J. van den, Broeck, C. Van Den, Vander-Hyde, D. C., van der Sluys, M., Van de Walle, A., van Dongen, J., Vandra, K., van Haevermaet, H., van Heijningen, J. V., Vanosky, J., van Putten, M. H. P. M., van Ranst, Z., van Remortel, N., Vardaro, M., Vargas, A. F., Varma, V., Vasúth, M., Vecchio, A., Vedovato, G., Veitch, J., Veitch, P. J., Venikoudis, S., Venneberg, J., Verdier, P., Verkindt, D., Verma, B., Verma, P., Verma, Y., Vermeulen, S. M., Veske, D., Vetrano, F., Veutro, A., Vibhute, A. M., Viceré, A., Vidyant, S., Viets, A. D., Vijaykumar, A., Vilkha, A., Villa-Ortega, V., Vincent, E. T., Vinet, J. -Y., Viret, S., Virtuoso, A., Vitale, S., Vocca, H., Voigt, D., von Reis, E. R. G., von Wrangel, J. S. A., Vyatchanin, S. P., Wade, L. E., Wade, M., Wagner, K. J., Walet, R. C., Walker, M., Wallace, G. S., Wallace, L., Wang, H., Wang, J. Z., Wang, W. H., Wang, Z., Waratkar, G., Ward, R. L., Warner, J., Was, M., Washimi, T., Washington, N. Y., Watarai, D., Wayt, K. E., Weaver, B., Weaving, C. R., Webster, S. A., Weinert, M., Weinstein, A. J., Weiss, R., Weller, C. M., Weller, R. A., Wellmann, F., Wen, L., Weßels, P., Wette, K., Whelan, J. T., White, D. D., Whiting, B. F., Whittle, C., Wildberger, J. B., Wilk, O. S., Wilken, D., Willetts, K., Williams, D., Williams, M. J., Williams, N. S., Willis, J. L., Willke, B., Wils, M., Wipf, C. C., Woan, G., Woehler, J., Wofford, J. K., Wolfe, N. E., Wong, D., Wong, H. T., Wong, H. W. Y., Wong, I. C. F., Wright, J. L., Wright, M., Wu, C., Wu, D. S., Wu, H., Wysocki, D. M., Xiao, L., Xu, V. A., Xu, Y., Yadav, N., Yamamoto, H., Yamamoto, K., Yamamoto, M., Yamamoto, T. S., Yamamoto, T., Yamamura, S., Yamazaki, R., Yan, S., Yan, T., Yang, F. W., Yang, F., Yang, K. Z., Yang, L. -C., Yang, Y., Yarbrough, Z., Yeh, S. -W., Yelikar, A. B., Yeung, S. M. C., Yin, X., Yokoyama, J., Yokozawa, T., Yoo, J., Yu, H., Yuzurihara, H., Zadrożny, A., Zannelli, A. J., Zanolin, M., Zeeshan, M., Zelenova, T., Zendri, J. -P., Zeoli, M., Zerrad, M., Zevin, M., Zhang, A. C., Zhang, J., Zhang, L., Zhang, R., Zhang, T., Zhang, Y., Zhao, C., Zhao, Yue, Zhao, Yuhang, Zheng, Y., Zhong, H., Zhong, S., Zhou, R., Zhu, Z. -H., Zimmerman, A. B., Zucker, M. E., and Zweizig, J.
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Astrophysics - High Energy Astrophysical Phenomena ,General Relativity and Quantum Cosmology - Abstract
We present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search includes 636 GW candidates received in low latency, 86 of which have been confirmed by the offline analysis and included in the third cumulative Gravitational-Wave Transient Catalogs (GWTC-3). Targeted searches were carried out on the entire GW sample using the maximum--likelihood NITRATES pipeline on the BAT data made available via the GUANO infrastructure. We do not detect any significant electromagnetic emission that is temporally and spatially coincident with any of the GW candidates. We report flux upper limits in the 15-350 keV band as a function of sky position for all the catalog candidates. For GW candidates where the Swift-BAT false alarm rate is less than 10$^{-3}$ Hz, we compute the GW--BAT joint false alarm rate. Finally, the derived Swift-BAT upper limits are used to infer constraints on the putative electromagnetic emission associated with binary black hole mergers., Comment: 50 pages, 10 figures, 4 tables
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- 2024
21. Endoscopic ultrasound in patients with resectable perihilar cholangiocarcinoma: impact on clinical decision-making
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David M. de Jong, Sanne van de Vondervoort, Roy S. Dwarkasing, Michael Doukas, Rogier P. Voermans, Robert C. Verdonk, Wojciech G. Polak, Jeroen de Jonge, Bas Groot Koerkamp, Marco J. Bruno, and Lydi M.J.W. van Driel
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Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Background and study aims Accurate assessment of the lymph node (LN) status is crucial in resectable perihilar cholangiocarcinoma (pCCA) to prevent major surgery in patients with extraregional metastatic LNs (MLNs). This study investigates the added value of preoperative endoscopic ultrasound (EUS) with or without tissue acquisition (TA) for the detection of MLNs in patients with resectable pCCA. Patients and methods In this retrospective, multicenter cohort study, patients with potentially resectable pCCA who underwent EUS preoperatively between 2010–2020, were included. The clinical impact of EUS-TA was defined as the percentage of patients who did not undergo surgical resection due to MLNs found with EUS-TA. Findings of cross-sectional imaging were compared with EUS-TA findings and surgery. Results EUS was performed on 141 patients, of whom 107 (76 %) had suspicious LNs on cross-sectional imaging. Surgical exploration was prevented in 20 patients (14 %) because EUS-TA detected MLNs, of which 17 (85 %) were extraregional. Finally, 74 patients (52 %) underwent surgical exploration followed by complete resection in 40 (28 %). MLNs were identified at definitive pathology in 24 (33 %) patients, of which 9 (38 %) were extraregional and 15 (63 %) regional. Conclusions EUS-TA may be of value in patients with potentially resectable pCCA based on preoperative cross-sectional imaging, regardless of lymphadenopathy at cross-sectional imaging. A prospective study in which a comprehensive EUS investigation with LN assessment and EUS-TA of LNs is performed routinely should confirm this promise.
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- 2023
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22. National Access to EyeSi Simulation: A Comparative Study Among U.S. Ophthalmology Residency Programs
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Jessinta Oseni, Ayobami Adebayo, Nilesh Raval, Jee Young Moon, Viral Juthani, Roy S. Chuck, and Anurag Shrivastava
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eyesi simulation ,distribution ,ophthalmology residency programs ,program ranking ,va affiliation ,Ophthalmology ,RE1-994 - Abstract
Purpose The aim of this study was to evaluate regional disparities in access to EyeSi surgical simulation training among U.S. ophthalmology residency programs. Methods Access to EyeSi simulation was determined from sales data (2021) provided by VRMagic. Key demographic metrics of the primary counties of U.S. residency training programs were retrieved from the U.S. Census Bureau Database (2019) and PolicyMap (2021). Demographic metrics, Veterans Affairs (VA) hospital affiliation, and Doximity residency program ranking (2021) were compared using the Mann–Whitney U test and Fisher's exact test. Results A total of 124 residency training programs across 95 U.S. counties were included. Regional density (number of EyeSi simulators/million people) was calculated; the west had a significantly lower density when compared with the northeast (NE), south, and midwest (0.4 vs 1.0, 1.3, 1.1, respectively). In the NE, there was a significantly lower population of Blacks (p = 0.01), Hispanics (p = 0.028), and Native Americans (p = 0.008) residing in counties with access to EyeSi, compared with counties without EyeSi access. Programs with EyeSi access (N = 95) had a median Doximity ranking of 52.5, whereas programs without EyeSi access (N = 35) had a lower median ranking of 94 (p
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- 2023
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23. Real‐world evidence in a national health service: results of the UK CardioMEMS HF System Post‐Market Study
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Martin R. Cowie, Andrew Flett, Peter Cowburn, Paul Foley, Badrinathan Chandrasekaran, Ian Loke, Chris Critoph, Roy S. Gardner, Kaushik Guha, Tim R. Betts, Gerry Carr‐White, Amir Zaidi, Hoong Sern Lim, Carl Hayward, Ashish Patwala, Dominic Rogers, Stephen Pettit, Carlo Gazzola, John Henderson, and Philip B. Adamson
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CardioMEMS™ HF System ,Clinical trial results ,UK ,Haemodynamic monitoring ,Heart failure ,Pulmonary artery pressure ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims The CardioMEMS HF System Post‐Market Study (COAST) was designed to evaluate the safety, effectiveness, and feasibility of haemodynamic‐guided heart failure (HF) management using a small sensor implanted in the pulmonary artery of New York Heart Association (NYHA) Class III HF patients in the UK, Europe, and Australia. Methods and results COAST is a prospective, international, multicentre, open‐label clinical study (NCT02954341). The primary clinical endpoint compares annualized HF hospitalization rates after 1 year of haemodynamic‐guided management vs. the year prior to sensor implantation in patients with NYHA Class III symptoms and a previous HF hospitalization. The primary safety endpoints assess freedom from device/system‐related complications and pressure sensor failure after 2 years. Results from the first 100 patients implanted at 14 out of the 15 participating centres in the UK are reported here. At baseline, all patients were in NYHA Class III, 70% were male, mean age was 69 ± 12 years, and 39% had an aetiology of ischaemic cardiomyopathy. The annualized HF hospitalization rate after 12 months was 82% lower [95% confidence interval 72–88%] than the previous 12 months (0.27 vs. 1.52 events/patient‐year, respectively, P
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- 2022
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24. Principal Hugoniots of Promethium, Terbium, Thulium, Lutetium, and Actinium in a Wide Pressure Range
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Leonid Burakovsky, Dean L. Preston, Scott D. Ramsey, Sky K. Sjue, Charles E. Starrett, and Roy S. Baty
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quantum phase transitions ,melting curve ,shear modulus ,equation of state ,material modeling ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
We present the analytic forms of the principal Hugoniots of actinium (Ac) and the lanthanide promethium (Pm), which have both never been measured or calculated before, as well as those of terbium (Tb), thulium (Tm), and lutetium (Lu), the three least studied of the remaining lanthanides. They are based on our new analytic model of principal Hugoniot. A comparison of the five Hugoniots to our own independent theoretical calculations demonstrates very good agreement in every case, but each of the Hugoniots of Tb, Tm, and Ac from the TEFIS database, which ours are also compared to, appear to violate Johnson’s theoretical constraint 4<ηmax<7 for the maximum compression ratio ηmax, which corresponds to the Hugoniot turnaround point. Possible reason for this behavior of the TEFIS Hugoniots is briefly discussed.
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- 2023
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25. Moxifloxacin releasing intraocular implant based on a cross-linked hyaluronic acid membrane
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Dong Ju Kim, Mi-Young Jung, Joo-Hee Park, Ha-Jin Pak, Martha Kim, Roy S. Chuck, and Choul Yong Park
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Medicine ,Science - Abstract
Abstract Intraocular antibiotic delivery is an important technique to prevent bacterial infection after ophthalmic surgery, such as cataract surgery. Conventional drug delivery methods, such as antibiotic eye drops, have limitations for intraocular drug delivery due to the intrinsic barrier effect of the cornea. Therefore, frequent instillation of antibiotic eyedrops is necessary to reach a sufficient bactericidal concentration inside the eye. In this study, an intraocular implant, MXF-HA, that combines hyaluronic acid (HA) and moxifloxacin (MXF) was developed to increase the efficiency of intraocular drug delivery after surgery. MXF-HA is manufactured as a thin, transparent, yellow-tinted membrane. When inserted into the eye in a dry state, MXF-HA is naturally hydrated and settles in the eye, and the MXF contained therein is delivered by hydrolysis of the polymer over time. It was confirmed through in vivo experiments that MXF delivery was maintained in the anterior chamber of the eye at a concentration sufficient to inhibit Pseudomonas aeruginosa and Staphylococcus aureus for more than 5 days after implantation. These results suggest that MXF-HA can be utilized as a potential drug delivery method for the prevention and treatment of bacterial infections after ophthalmic surgery.
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- 2021
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26. ABO Blood Group and Outcomes in Patients with COVID-19 Admitted in the Intensive Care Unit (ICU): A Retrospective Study in a Tertiary-Level Hospital in Bangladesh
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Halim MR, Saha S, Haque IU, Jesmin S, Nishat RJ, Islam AA, Roy S, Haque MMA, Islam MM, Hamid T, Ahmed KN, Talukder MAI, Ahmed A, Hasan E, Ananna N, Mohsin FM, and Hawlader MDH
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covid-19 ,icu ,abo blood group ,bangladesh ,Medicine (General) ,R5-920 - Abstract
Mohammad Rabiul Halim,1,* Shuvajit Saha,2,* Injamam Ull Haque,1 Sadia Jesmin,1 Rahatul Jannat Nishat,3 ASMD Ashraful Islam,2 Seema Roy,4 Miah Md Akiful Haque,5 Md Motiul Islam,1 Tarikul Hamid,1 Kazi Nuruddin Ahmed,1 Md Azharul Islam Talukder,1 Arif Ahmed,1 Emran Hasan,2 Nurjahan Ananna,1 Faroque Md Mohsin,6 Mohammad Delwer Hossain Hawlader7 1Department of Critical Care Medicine, Central Police Hospital, Dhaka, Bangladesh; 2Department of Maternal and Child Health, Projahnmo Research Foundation, Dhaka, Bangladesh; 3Department of Physiology, Sir Salimullah Medical College, Dhaka, Bangladesh; 4Department of Medicine, Popular Medical College, Dhaka, Bangladesh; 5Department of Epidemiology, Public Health Professional Development Initiative (PPDI), Dhaka, Bangladesh; 6Directorate General of Health Services (DGHS), Ministry of Health and Family Welfare, Dhaka, Bangladesh; 7Department of Public Health, North South University, Dhaka, Bangladesh*These authors contributed equally to this workCorrespondence: Mohammad Delwer Hossain Hawlader Email mohammad.hawlader@northsouth.eduPurpose: The world is heavily suffering from the COVID-19 pandemic for more than a year, with over 191 million confirmed cases and more than 4.1 million deaths to date. Previous studies have explored several risk factors for coronavirus disease 2019 (COVID-19), but there is still a lack of association with ABO blood type. This study aimed to find out the relationship between the ABO blood group and COVID-19 outcomes in Bangladesh.Subjects and Methods: This retrospective cross-sectional study was conducted in the intensive care unit (ICU) of a tertiary-level COVID-dedicated hospital in Dhaka city, Bangladesh, between April 2020 and November 2020. Records from 771 critically ill patients were extracted who were confirmed for COVID-19 by reverse transcriptase-polymerase chain reaction (RT-PCR) assay, and blood grouping records were available in the health records.Results: The blood groups were 37.35%, 17.38%, 26.46%, and 18.81% for A, B, AB, and O type, respectively. Clinical symptoms were significantly more common in patients with blood type A (p < 0.05). Patients with blood type A had higher WBC counts and peak serum ferritin levels and both were statistically significant (p < 0.001). Patients with blood type A had a greater need for supplemental oxygen, and they were more likely to die in comparison to the patients with other blood types (p < 0.05). In multivariable analysis, our primary outcome death was significantly associated with blood type A (AOR: 3.49, 95% CI: 1.57– 7.73) while adjusting for age, male gender, and non-communicable diseases.Conclusion: Based on this study results, it can be concluded that the COVID-19 patients with blood type A have a higher chance of death and other complications. The authors recommend blood grouping before treating the COVID-19 patients, and healthcare workers should prioritize treating the patients based on that result.Keywords: COVID-19, ICU, ABO blood group, Bangladesh
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- 2021
27. Measurement of exclusive $J/\psi$ and $\psi(2S)$ production at $\sqrt{s}=13$ TeV
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LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataíde, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Bao, H., Leite, J. Baptista de Souza, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bassi, G., Batsukh, B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bowcock, T. J. V., Boyer, A., Bozzi, C., Braat, P., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. Curras, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Daniel, J., Danilina, A., d'Argent, P., Davidson, A., Davies, J. E., Davis, A., Francisco, O. De Aguiar, De Angelis, C., De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, P., De Vellis, F., de Vries, J. A., Debernardis, F., Decamp, D., Dedu, V., Del Buono, L., Delaney, B., Dembinski, H. -P., Deng, J., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Nezza, P., Diachkov, I., Didenko, S., Ding, S., Dittmann, L., Dobishuk, V., Docheva, A. D., Dong, C., Donohoe, A. M., Dordei, F., Reis, A. C. dos, Dowling, A. D., Duan, W., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Duras, M. M., Durham, J. M., Durmus, O. D., Dziurda, A., Dzyuba, A., Easo, S., Eckstein, E., Egede, U., Egorychev, A., Egorychev, V., Eisenhardt, S., Ejopu, E., Eklund, L., Elashri, M., Ellbracht, J., Ely, S., Ene, A., Epple, E., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farmer, K., Fazzini, D., Felkowski, L., Feng, M., Feo, M., Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Rodrigues, F. Ferreira, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Fischer, K. L., Fitzgerald, D. S., Fitzpatrick, C., Fleuret, F., Fontana, M., Foreman, L. F., Forty, R., Foulds-Holt, D., Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Fujii, Y., Fulghesu, T., Gabriel, E., Galati, G., Galati, M. D., Torreira, A. Gallas, Galli, D., Gambetta, S., Gandelman, M., Gandini, P., Ganie, B., Gao, H., Gao, R., Gao, Y., Garau, M., Martin, L. M. Garcia, Moreno, P. Garcia, Pardiñas, J. García, Garg, K. G., Garrido, L., Gaspar, C., Geertsema, R. E., Gerken, L. L., Gersabeck, E., Gersabeck, M., Gershon, T., Ghorbanimoghaddam, Z., Giambastiani, L., Giasemis, F. I., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Gironell, P. Gironella, Giugliano, C., Giza, M. A., Gkougkousis, E. L., Glaser, F. C., Gligorov, V. V., Göbel, C., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Fernandez, S. Gomez, Abrantes, F. Goncalves, Goncerz, M., Gong, G., Gooding, J. A., Gorelov, I. V., Gotti, C., Grabowski, J. P., Cardoso, L. A. Granado, Graugés, E., Graverini, E., Grazette, L., Graziani, G., Grecu, A. T., Greeven, L. M., Grieser, N. A., Grillo, L., Gromov, S., Gu, C., Guarise, M., Guittiere, M., Guliaeva, V., Günther, P. A., Guseinov, A. -K., Gushchin, E., Guz, Y., Gys, T., Habermann, K., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Hajheidari, M., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Han, Q., Han, X., Hansmann-Menzemer, S., Hao, L., Harnew, N., Hartmann, M., He, J., Hemmer, F., Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Gascon, P. Herrero, Heuel, J., Hicheur, A., Mendizabal, G. Hijano, Hill, D., Hollitt, S. E., Horswill, J., Hou, R., Hou, Y., Howarth, N., Hu, J., Hu, W., Hu, X., Huang, W., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., Jiang, Y. J., John, M., Johnson, D., Jones, C. R., Jones, T. P., Joshi, S., Jost, B., Jurik, N., Juszczak, I., Kaminaris, D., Kandybei, S., Kane, M., Kang, Y., Kar, C., Karacson, M., Karpenkov, D., Kauniskangas, A., Kautz, J. W., Keizer, F., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Khreich, G., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Kleijne, N., Klimaszewski, K., Kmiec, M. R., Koliiev, S., Kolk, L., Konoplyannikov, A., Kopciewicz, P., Koppenburg, P., Korolev, M., Kostiuk, I., Kot, O., Kotriakhova, S., Kozachuk, A., Kravchenko, P., Kravchuk, L., Kreps, M., Krokovny, P., Krupa, W., Krzemien, W., Kshyvanskyi, O. K., Kubat, J., Kubis, S., Kucharczyk, M., Kudryavtsev, V., Kulikova, E., Kupsc, A., Kutsenko, B. K., Lacarrere, D., Lai, A., Lampis, A., Lancierini, D., Gomez, C. Landesa, Lane, J. J., Lane, R., Langenbruch, C., Langer, J., Lantwin, O., Latham, T., Lazzari, F., Lazzeroni, C., Gac, R. Le, Lefèvre, R., Leflat, A., Legotin, S., Lehuraux, M., Cid, E. Lemos, Leroy, O., Lesiak, T., Leverington, B., Li, A., Li, H., Li, K., Li, L., Li, P., Li, P. -R., Li, Q., Li, S., Li, T., Li, Y., Lian, Z., Liang, X., Libralon, S., Lin, C., Lin, T., Lindner, R., Lisovskyi, V., Litvinov, R., Liu, F. L., Liu, G., Liu, K., Liu, S., Liu, Y., Liu, Y. L., Salvia, A. Lobo, Loi, A., Castro, J. Lomba, Long, T., Lopes, J. H., Huertas, A. Lopez, Soliño, S. López, Villalpando, A. Loya, Lucarelli, C., Lucchesi, D., Martinez, M. Lucio, Lukashenko, V., Luo, Y., Lupato, A., Luppi, E., Lynch, K., Lyu, X. -R., Ma, G. M., Ma, R., Maccolini, S., Machefert, F., Maciuc, F., Mack, B., Mackay, I., Mackey, L. M., Mohan, L. R. Madhan, Madurai, M. J., Maevskiy, A., Magdalinski, D., Maisuzenko, D., Majewski, M. W., Malczewski, J. J., Malde, S., Malentacca, L., Malinin, A., Maltsev, T., Manca, G., Mancinelli, G., Mancuso, C., Escalero, R. Manera, Manuzzi, D., Marangotto, D., Marchand, J. F., Marchevski, R., Marconi, U., Mariani, S., Benito, C. Marin, Marks, J., Marshall, A. M., Martelli, G., Martellotti, G., Martinazzoli, L., Martinelli, M., Santos, D. Martinez, Vidal, F. Martinez, Massafferri, A., Matev, R., Mathad, A., Matiunin, V., Matteuzzi, C., Mattioli, K. R., Mauri, A., Maurice, E., Mauricio, J., Mayencourt, P., Mazurek, M., McCann, M., Mcconnell, L., McGrath, T. H., McHugh, N. T., McNab, A., McNulty, R., Meadows, B., Meier, G., Melnychuk, D., Meng, F. M., Merk, M., Merli, A., Garcia, L. Meyer, Miao, D., Miao, H., Mikhasenko, M., Milanes, D. A., Minotti, A., Minucci, E., Miralles, T., Mitreska, B., Mitzel, D. S., Modak, A., Mödden, A., Mohammed, R. A., Moise, R. D., Mokhnenko, S., Mombächer, T., Monk, M., Monteil, S., Gomez, A. Morcillo, Morello, G., Morello, M. J., Morgenthaler, M. P., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Mu, Z. M., Muhammad, E., Muheim, F., Mulder, M., Müller, K., Muñoz-Rojas, F., Murta, R., Naik, P., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Nicolini, J., Nicotra, D., Niel, E. M., Nikitin, N., Nogarolli, P., Nogga, P., Nolte, N. S., Normand, C., Fernandez, J. Novoa, Nowak, G., Nunez, C., Nur, H. N., Oblakowska-Mucha, A., Obraztsov, V., Oeser, T., Okamura, S., Okhotnikov, A., Okhrimenko, O., Oldeman, R., Oliva, F., Olocco, M., Onderwater, C. J. G., O'Neil, R. H., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Ozcelik, O., Padee, A., Padeken, K. O., Pagare, B., Pais, P. R., Pajero, T., Palano, A., Palutan, M., Panshin, G., Paolucci, L., Papanestis, A., Pappagallo, M., Pappalardo, L. L., Pappenheimer, C., Parkes, C., Passalacqua, B., Passaleva, G., Passaro, D., Pastore, A., Patel, M., Patoc, J., Patrignani, C., Paul, A., Pawley, C. J., Pellegrino, A., Peng, J., Altarelli, M. Pepe, Perazzini, S., Pereima, D., Da Costa, H. Pereira, Castro, A. Pereiro, Perret, P., Perro, A., Petridis, K., Petrolini, A., Pfaller, J. P., Pham, H., Pica, L., Piccini, M., Pietrzyk, B., Pietrzyk, G., Pinci, D., Pisani, F., Pizzichemi, M., Placinta, V., Casasus, M. Plo, Polci, F., Lener, M. Poli, Poluektov, A., Polukhina, N., Polyakov, I., Polycarpo, E., Ponce, S., Popov, D., Poslavskii, S., Prasanth, K., Prouve, C., Pugatch, V., Punzi, G., Qasim, S., Qian, Q. Q., Qian, W., Qin, N., Qu, S., Quagliani, R., Trejo, R. I. Rabadan, Rademacker, J. H., Rama, M., García, M. Ramírez, De Oliveira, V. Ramos, Pernas, M. Ramos, Rangel, M. S., Ratnikov, F., Raven, G., De Miguel, M. Rebollo, Redi, F., Reich, J., Reiss, F., Ren, Z., Resmi, P. K., Ribatti, R., Ricart, G. R., Riccardi, D., Ricciardi, S., Richardson, K., Richardson-Slipper, M., Rinnert, K., Robbe, P., Robertson, G., Rodrigues, E., Fernandez, E. Rodriguez, Lopez, J. A. Rodriguez, Rodriguez, E. Rodriguez, Rogovskiy, A., Rolf, D. L., Roloff, P., Romanovskiy, V., Lamas, M. Romero, Vidal, A. Romero, Romolini, G., Ronchetti, F., Rong, T., Rotondo, M., Roy, S. R., Rudolph, M. S., Diaz, M. Ruiz, Fernandez, R. A. Ruiz, Vidal, J. Ruiz, Ryzhikov, A., Ryzka, J., Saavedra-Arias, J. J., Silva, J. J. Saborido, Sadek, R., Sagidova, N., Sahoo, D., Sahoo, N., Saitta, B., Salomoni, M., Gras, C. Sanchez, Sanderswood, I., Santacesaria, R., Rios, C. Santamarina, Santimaria, M., Santoro, L., Santovetti, E., Saputi, A., Saranin, D., Sarnatskiy, A., Sarpis, G., Sarpis, M., Satriano, C., Satta, A., Saur, M., Savrina, D., Sazak, H., Sborzacchi, F., Smead, L. G. Scantlebury, Scarabotto, A., Schael, S., Scherl, S., Schiller, M., Schindler, H., Schmelling, M., Schmidt, B., Schmitt, S., Schmitz, H., Schneider, O., Schopper, A., Schubiger, M., Schulte, N., Schulte, S., Schune, M. H., Schwemmer, R., Schwering, G., Sciascia, B., Sciuccati, A., Sellam, S., Semennikov, A., Senger, T., Soares, M. Senghi, Sergi, A., Serra, N., Sestini, L., Seuthe, A., Shang, Y., Shangase, D. M., Shapkin, M., Sharma, R. S., Shchemerov, I., Shchutska, L., Shears, T., Shekhtman, L., Shen, Z., Sheng, S., Shevchenko, V., Shi, B., Shi, Q., Shimizu, Y., Shmanin, E., Shorkin, R., Shupperd, J. D., Coutinho, R. Silva, Simi, G., Simone, S., Skidmore, N., Skwarnicki, T., Slater, M. W., Smallwood, J. C., Smith, E., Smith, K., Smith, M., Snoch, A., Lavra, L. Soares, Sokoloff, M. D., Soler, F. J. P., Solomin, A., Solovev, A., Solovyev, I., Song, R., Song, Y., Song, Y. S., De Almeida, F. L. Souza, De Paula, B. Souza, Norella, E. Spadaro, Spedicato, E., Speer, J. G., Spiridenkov, E., Spradlin, P., Sriskaran, V., Stagni, F., Stahl, M., Stahl, S., Stanislaus, S., Stein, E. N., Steinkamp, O., Stenyakin, O., Stevens, H., Strekalina, D., Su, Y., Suljik, F., Sun, J., Sun, L., Sun, Y., Sundfeld, D., Sutcliffe, W., Swallow, P. N., Swystun, F., Szabelski, A., Szumlak, T., Tan, Y., Tat, M. D., Terentev, A., Terzuoli, F., Teubert, F., Thomas, E., Thompson, D. J. D., Tilquin, H., Tisserand, V., T'Jampens, S., Tobin, M., Tomassetti, L., Tonani, G., Tong, X., Machado, D. Torres, Toscano, L., Tou, D. Y., Trippl, C., Tuci, G., Tuning, N., Uecker, L. H., Ukleja, A., Unverzagt, D. J., Ursov, E., Usachov, A., Ustyuzhanin, A., Uwer, U., Vagnoni, V., Valenti, G., Canudas, N. Valls, Van Hecke, H., van Herwijnen, E., Van Hulse, C. B., Van Laak, R., van Veghel, M., Vasquez, G., Gomez, R. Vazquez, Regueiro, P. Vazquez, Sierra, C. Vázquez, Vecchi, S., Velthuis, J. J., Veltri, M., Venkateswaran, A., Vesterinen, M., Diaz, M. Vieites, Vilasis-Cardona, X., Figueras, E. Vilella, Villa, A., Vincent, P., Volle, F. C., Bruch, D. vom, Voropaev, N., Vos, K., Vouters, G., Vrahas, C., Wagner, J., Walsh, J., Walton, E. J., Wan, G., Wang, C., Wang, G., Wang, J., Wang, M., Wang, N. W., Wang, R., Wang, X., Wang, X. W., Wang, Y., Wang, Z., Ward, J. A., Waterlaat, M., Watson, N. K., Websdale, D., Wei, Y., Wendel, J., Westhenry, B. D. C., White, D. J., Whitehead, M., Whiter, E., Wiederhold, A. R., Wiedner, D., Wilkinson, G., Wilkinson, M. K., Williams, M., Williams, M. R. J., Williams, R., Wilson, F. F., Wislicki, W., Witek, M., Witola, L., Wong, C. P., Wormser, G., Wotton, S. A., Wu, H., Wu, J., Wu, Y., Wu, Z., Wyllie, K., Xian, S., Xiang, Z., Xie, Y., Xu, A., Xu, J., Xu, L., Xu, M., Xu, Z., Yang, D., Yang, K., Yang, S., Yang, X., Yang, Y., Yang, Z., Yeroshenko, V., Yeung, H., Yin, H., Yu, C. Y., Yu, J., Yuan, X., Zaffaroni, E., Zavertyaev, M., Zdybal, M., Zeng, C., Zeng, M., Zhang, C., Zhang, D., Zhang, J., Zhang, L., Zhang, S., Zhang, Y., Zhang, Y. Z., Zhao, Y., Zharkova, A., Zhelezov, A., Zheng, S. Z., Zheng, X. Z., Zheng, Y., Zhou, T., Zhou, X., Zhou, Y., Zhovkovska, V., Zhu, L. Z., Zhu, X., Zhukov, V., Zhuo, J., Zou, Q., Zuliani, D., and Zunica, G.
- Subjects
High Energy Physics - Experiment - Abstract
Measurements are presented of the cross-section for the central exclusive production of $J/\psi\to\mu^+\mu^-$ and $\psi(2S)\to\mu^+\mu^-$ processes in proton-proton collisions at $\sqrt{s} = 13 $ TeV with 2016-2018 data. They are performed by requiring both muons to be in the LHCb acceptance (with pseudorapidity $2<\eta_{\mu^\pm} < 4.5$) and mesons in the rapidity range $2.0 < y < 4.5$. The integrated cross-section results are \begin{equation*} \sigma_{J/\psi\to\mu^+\mu^-}(2.0
- Published
- 2024
28. Measurement of $CP$ violation in ${B^0}\rightarrow{D^{+}D^{-}}$ and ${B^{0}_{s}}\rightarrow{D^{+}_{s}D^{-}_{s}}$ decays
- Author
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LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataíde, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Balzani, L., Bao, H., Leite, J. Baptista de Souza, Pretel, C. Barbero, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bashir, S., Bassi, G., Batsukh, B., Battista, P. B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Behling, N. A., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Bordelius, A., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bovill, M., Bowcock, T. J. V., Boyer, A., Bozzi, C., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Caillet, A. C., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chiotopoulos, X., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Colonna, M. 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- Subjects
High Energy Physics - Experiment - Abstract
A time-dependent, flavour-tagged measurement of $CP$ violation is performed with ${B^0}\rightarrow{D^{+}D^{-}}$ and ${B^{0}_{s}}\rightarrow{D^{+}_{s}D^{-}_{s}}$ decays, using data collected by the LHCb detector in proton-proton collisions at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 6 fb$^{-1}$. In ${B^0}\rightarrow{D^{+}D^{-}}$ decays the $CP$-violation parameters are measured to be \begin{align} S_{D^{+}D^{-}} & = -0.552 \pm 0.100\,\text{(stat)} \pm 0.010\,\text{(syst)}, \nonumber \newline C_{D^{+}D^{-}} & = \phantom{-}0.128 \pm0.103\,\text{(stat)} \pm 0.010\,\text{(syst)}. \nonumber \end{align} In $B^{0}_{s} \rightarrow D^{+}_{s}D^{-}_{s}$ decays the $CP$-violating parameter formulation in terms of $\phi_{s}$ and $|\lambda|$ results in \begin{align} \phi_{s} & = -0.086 \pm 0.106 \,\text{(stat)} \pm 0.028\,\text{(syst)} \,\text{rad}, \nonumber \newline |\lambda_{D^{+}_{s}D^{-}_{s}}| & = \phantom{-}1.145 \pm 0.126\,\text{(stat)} \pm 0.031\,\text{(syst)}. \nonumber \end{align} These results represent the most precise single measurement of the $CP$-violation parameters in their respective channels. For the first time in a single measurement, $CP$ symmetry is observed to be violated in ${B^0}\rightarrow{D^{+}D^{-}}$ decays with a significance exceeding six standard deviations., Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://lbfence.cern.ch/alcm/public/analysis/full-details/3262/ (LHCb public pages)
- Published
- 2024
29. Measurement of $\it{\Lambda}_\it{b}^0$, $\it{\Lambda}_\it{c}^+$ and $\it{\Lambda}$ decay parameters using $\it{\Lambda}_\it{b}^0 \to \it{\Lambda}_\it{c}^+ h^-$ decays
- Author
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LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataide, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Balzani, L., Bao, H., Leite, J. Baptista de Souza, Pretel, C. Barbero, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bashir, S., Bassi, G., Batsukh, B., Battista, P. B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Behling, N. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Bordelius, A., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bovill, M., Bowcock, T. J. V., Boyer, A., Bozzi, C., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Caillet, A. C., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chiotopoulos, X., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Colonna, M. C., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. Curras, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Daniel, J., Danilina, A., d'Argent, P., Davidson, A., Davies, J. E., Davis, A., Francisco, O. De Aguiar, De Angelis, C., De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, P., De Vellis, F., de Vries, J. A., Debernardis, F., Decamp, D., Dedu, V., Dekkers, S., Del Buono, L., Delaney, B., Dembinski, H. -P., Deng, J., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Nezza, P., Diachkov, I., Didenko, S., Ding, S., Dittmann, L., Dobishuk, V., Docheva, A. D., Dong, C., Donohoe, A. M., Dordei, F., Reis, A. C. dos, Dowling, A. D., Duan, W., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Duras, M. M., Durham, J. M., Durmus, O. D., Dziurda, A., Dzyuba, A., Easo, S., Eckstein, E., Egede, U., Egorychev, A., Egorychev, V., Eisenhardt, S., Ejopu, E., Eklund, L., Elashri, M., Ellbracht, J., Ely, S., Ene, A., Epple, E., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farmer, K., Fazzini, D., Felkowski, L., Feng, M., Feo, M., Casani, A. Fernandez, Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Rodrigues, F. Ferreira, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Fischer, K. M., Fitzgerald, D. S., Fitzpatrick, C., Fleuret, F., Fontana, M., Foreman, L. F., Forty, R., Foulds-Holt, D., Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Fujii, Y., Fulghesu, T., Gabriel, E., Galati, G., Galati, M. D., Torreira, A. 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A., Guseinov, A. -K., Gushchin, E., Guz, Y., Gys, T., Habermann, K., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Hajheidari, M., Hallett, G. H., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Han, Q., Han, X., Hansmann-Menzemer, S., Hao, L., Harnew, N., Hartmann, M., Hashmi, S., He, J., Hemmer, F., Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Gascon, P. Herrero, Heuel, J., Hicheur, A., Mendizabal, G. Hijano, Hill, D., Hollitt, S. E., Horswill, J., Hou, R., Hou, Y., Howarth, N., Hu, J., Hu, W., Hu, X., Huang, W., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., Jiang, Y. J., John, M., Rajan, A. John Rubesh, Johnson, D., Jones, C. R., Jones, T. P., Joshi, S., Jost, B., Castella, J. 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- Subjects
High Energy Physics - Experiment - Abstract
A comprehensive study of the angular distributions in the bottom-baryon decays $\it{\Lambda}^\mathrm{0}_b\to\it{\Lambda}_c^+ h^-(h=\pi, K)$, followed by $\it{\Lambda}_c^+\to\it{\Lambda} h^+$ with $\it{\Lambda}\to \it{p} \pi^-$ or $\it{\Lambda}_c^+\to\it{p}\it{K}^0_\mathrm{S}$ decays, is performed using a data sample of proton-proton collisions corresponding to an integrated luminosity of $9~\mathrm{fb}^{-1}$ collected by the LHCb experiment at center-of-mass energies of 7, 8 and 13 $\mathrm{Te\kern -0.1em V}$. The decay parameters and the associated charge-parity ($C\!P$) asymmetries are measured, with no significant $C\!P$ violation observed. For the first time, the $\it{\Lambda}^\mathrm{0}_b \to \it{\Lambda}_c^+ h^-$ decay parameters are measured. The most precise measurements of the decay parameters $\alpha, \beta$ and $\gamma$ are obtained for $\it{\Lambda}_c^+$ decays and an independent measurement of the decay parameters for the strange-baryon $\it{\Lambda}$ decay is provided. The results deepen our understanding of weak decay dynamics in baryon decays., Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2024-017.html(LHCb public pages)
- Published
- 2024
30. Measurement of $C\!P$ violation observables in $D^+\rightarrow K^-K^+\pi^+$ decays
- Author
-
LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataíde, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Balzani, L., Bao, H., Leite, J. Baptista de Souza, Pretel, C. Barbero, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bashir, S., Bassi, G., Batsukh, B., Battista, P. B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Behling, N. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Bordelius, A., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bovill, M., Bowcock, T. J. V., Boyer, A., Bozzi, C., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Caillet, A. C., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Campos, A. C., Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chiotopoulos, X., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Colonna, M. C., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. Curras, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Daniel, J., Danilina, A., d'Argent, P., Davidson, A., Davies, J. E., Davis, A., Francisco, O. De Aguiar, De Angelis, C., De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, P., De Vellis, F., de Vries, J. A., Debernardis, F., Decamp, D., Dedu, V., Dekkers, S., Del Buono, L., Delaney, B., Dembinski, H. -P., Deng, J., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Nezza, P., Diachkov, I., Didenko, S., Ding, S., Dittmann, L., Dobishuk, V., Docheva, A. D., Dong, C., Donohoe, A. M., Dordei, F., Reis, A. C. dos, Dowling, A. D., Duan, W., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Duras, M. M., Durham, J. M., Durmus, O. D., Dziurda, A., Dzyuba, A., Easo, S., Eckstein, E., Egede, U., Egorychev, A., Egorychev, V., Eisenhardt, S., Ejopu, E., Eklund, L., Elashri, M., Ellbracht, J., Ely, S., Ene, A., Epple, E., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farmer, K., Fazzini, D., Felkowski, L., Feng, M., Feo, M., Casani, A. Fernandez, Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Rodrigues, F. Ferreira, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Fischer, K. L., Fitzgerald, D. S., Fitzpatrick, C., Fleuret, F., Fontana, M., Foreman, L. F., Forty, R., Foulds-Holt, D., Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Fujii, Y., Fulghesu, T., Gabriel, E., Galati, G., Galati, M. D., Torreira, A. Gallas, Galli, D., Gambetta, S., Gandelman, M., Gandini, P., Ganie, B., Gao, H., Gao, R., Gao, T. Q., Gao, Y., Garau, M., Martin, L. M. Garcia, Moreno, P. Garcia, Pardiñas, J. García, Garg, K. G., Garrido, L., Gaspar, C., Geertsema, R. E., Gerken, L. L., Gersabeck, E., Gersabeck, M., Gershon, T., Ghizzo, S. G., Ghorbanimoghaddam, Z., Giambastiani, L., Giasemis, F. I., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Girardey, L., Gironell, P. Gironella, Giugliano, C., Giza, M. A., Gkougkousis, E. L., Glaser, F. C., Gligorov, V. V., Göbel, C., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Fernandez, S. Gomez, Abrantes, F. Goncalves, Goncerz, M., Gong, G., Gooding, J. A., Gorelov, I. V., Gotti, C., Grabowski, J. P., Cardoso, L. A. Granado, Graugés, E., Graverini, E., Grazette, L., Graziani, G., Grecu, A. T., Greeven, L. M., Grieser, N. A., Grillo, L., Gromov, S., Gu, C., Guarise, M., Guerry, L., Guittiere, M., Guliaeva, V., Günther, P. A., Guseinov, A. -K., Gushchin, E., Guz, Y., Gys, T., Habermann, K., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Hajheidari, M., Hallett, G. H., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Han, Q., Han, X., Hansmann-Menzemer, S., Hao, L., Harnew, N., Hartmann, M., Hashmi, S., He, J., Hemmer, F., Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Gascon, P. Herrero, Heuel, J., Hicheur, A., Mendizabal, G. Hijano, Hill, D., Hollitt, S. E., Horswill, J., Hou, R., Hou, Y., Howarth, N., Hu, J., Hu, W., Hu, X., Huang, W., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., Jiang, Y. J., John, M., Rajan, A. John Rubesh, Johnson, D., Jones, C. R., Jones, T. P., Joshi, S., Jost, B., Castella, J. Juan, Jurik, N., Juszczak, I., Kaminaris, D., Kandybei, S., Kane, M., Kang, Y., Kar, C., Karacson, M., Karpenkov, D., Kauniskangas, A., Kautz, J. W., Kazanecki, M. K., Keizer, F., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Khreich, G., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Kleijne, N., Klimaszewski, K., Kmiec, M. R., Koliiev, S., Kolk, L., Konoplyannikov, A., Kopciewicz, P., Koppenburg, P., Korolev, M., Kostiuk, I., Kot, O., Kotriakhova, S., Kozachuk, A., Kravchenko, P., Kravchuk, L., Kreps, M., Krokovny, P., Krupa, W., Krzemien, W., Kshyvanskyi, O. K., Kubat, J., Kubis, S., Kucharczyk, M., Kudryavtsev, V., Kulikova, E., Kupsc, A., Kutsenko, B. K., Lacarrere, D., Gonzalez, P. Laguarta, Lai, A., Lampis, A., Lancierini, D., Gomez, C. Landesa, Lane, J. J., Lane, R., Lanfranchi, G., Langenbruch, C., Langer, J., Lantwin, O., Latham, T., Lazzari, F., Lazzeroni, C., Gac, R. Le, Lee, H., Lefèvre, R., Leflat, A., Legotin, S., Lehuraux, M., Cid, E. Lemos, Leroy, O., Lesiak, T., Leverington, B., Li, A., Li, C., Li, H., Li, K., Li, L., Li, P., Li, P. -R., Li, Q., Li, S., Li, T., Li, Y., Lian, Z., Liang, X., Libralon, S., Lin, C., Lin, T., Lindner, R., Lisovskyi, V., Litvinov, R., Liu, F. L., Liu, G., Liu, K., Liu, S., Liu, W., Liu, Y., Liu, Y. L., Salvia, A. Lobo, Loi, A., Castro, J. Lomba, Long, T., Lopes, J. H., Huertas, A. Lopez, Soliño, S. López, Lu, Q., Lucarelli, C., Lucchesi, D., Martinez, M. Lucio, Lukashenko, V., Luo, Y., Lupato, A., Luppi, E., Lynch, K., Lyu, X. -R., Ma, G. M., Ma, R., Maccolini, S., Machefert, F., Maciuc, F., Mack, B., Mackay, I., Mackey, L. M., Mohan, L. R. Madhan, Madurai, M. J., Maevskiy, A., Magdalinski, D., Maisuzenko, D., Majewski, M. W., Malczewski, J. J., Malde, S., Malentacca, L., Malinin, A., Maltsev, T., Manca, G., Mancinelli, G., Mancuso, C., Escalero, R. Manera, Manuzzi, D., Marangotto, D., Marchand, J. F., Marchevski, R., Marconi, U., Mariani, E., Mariani, S., Benito, C. Marin, Marks, J., Marshall, A. M., Martel, L., Martelli, G., Martellotti, G., Martinazzoli, L., Martinelli, M., Santos, D. Martinez, Vidal, F. Martinez, Massafferri, A., Matev, R., Mathad, A., Matiunin, V., Matteuzzi, C., Mattioli, K. R., Mauri, A., Maurice, E., Mauricio, J., Mayencourt, P., de Cos, J. Mazorra, Mazurek, M., McCann, M., Mcconnell, L., McGrath, T. H., McHugh, N. T., McNab, A., McNulty, R., Meadows, B., Meier, G., Melnychuk, D., Meng, F. M., Merk, M., Merli, A., Garcia, L. Meyer, Miao, D., Miao, H., Mikhasenko, M., Milanes, D. A., Minotti, A., Minucci, E., Miralles, T., Mitreska, B., Mitzel, D. S., Modak, A., Mohammed, R. A., Moise, R. D., Mokhnenko, S., Mombächer, T., Monk, M., Monteil, S., Gomez, A. Morcillo, Morello, G., Morello, M. J., Morgenthaler, M. P., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Mu, Z. M., Muhammad, E., Muheim, F., Mulder, M., Müller, K., Muñoz-Rojas, F., Murta, R., Naik, P., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Nicolini, J., Nicotra, D., Niel, E. M., Nikitin, N., Nogarolli, P., Nogga, P., Nolte, N. S., Normand, C., Fernandez, J. Novoa, Nowak, G., Nunez, C., Nur, H. N., Oblakowska-Mucha, A., Obraztsov, V., Oeser, T., Okamura, S., Okhotnikov, A., Okhrimenko, O., Oldeman, R., Oliva, F., Olocco, M., Onderwater, C. J. G., O'Neil, R. H., Osthues, D., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Ozcelik, O., Paciolla, F., Padee, A., Padeken, K. O., Pagare, B., Pais, P. R., Pajero, T., Palano, A., Palutan, M., Panshin, G., Paolucci, L., Papanestis, A., Pappagallo, M., Pappalardo, L. L., Pappenheimer, C., Parkes, C., Passalacqua, B., Passaleva, G., Passaro, D., Pastore, A., Patel, M., Patoc, J., Patrignani, C., Paul, A., Pawley, C. J., Pellegrino, A., Peng, J., Altarelli, M. 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W., Wang, Y., Wang, Z., Ward, J. A., Waterlaat, M., Watson, N. K., Websdale, D., Wei, Y., Wendel, J., Westhenry, B. D. C., White, C., Whitehead, M., Whiter, E., Wiederhold, A. R., Wiedner, D., Wilkinson, G., Wilkinson, M. K., Williams, M., Williams, M. R. J., Williams, R., Williams, Z., Wilson, F. F., Wislicki, W., Witek, M., Witola, L., Wong, C. P., Wormser, G., Wotton, S. A., Wu, H., Wu, J., Wu, Y., Wu, Z., Wyllie, K., Xian, S., Xiang, Z., Xie, Y., Xu, A., Xu, J., Xu, L., Xu, M., Xu, Z., Yang, D., Yang, K., Yang, S., Yang, X., Yang, Y., Yang, Z., Yeroshenko, V., Yeung, H., Yin, H., Yu, C. Y., Yu, J., Yuan, X., Yuan, Y, Zaffaroni, E., Zavertyaev, M., Zdybal, M., Zenesini, F., Zeng, C., Zeng, M., Zhang, C., Zhang, D., Zhang, J., Zhang, L., Zhang, S., Zhang, Y., Zhang, Y. Z., Zhao, Y., Zharkova, A., Zhelezov, A., Zheng, S. Z., Zheng, X. Z., Zheng, Y., Zhou, T., Zhou, X., Zhou, Y., Zhovkovska, V., Zhu, L. Z., Zhu, X., Zhukov, V., Zhuo, J., Zou, Q., Zuliani, D., and Zunica, G.
- Subjects
High Energy Physics - Experiment - Abstract
A search for violation of the charge-parity $C\!P$ symmetry in the $D^+\rightarrow K^-K^+\pi^+$ decay is presented, with proton-proton collision data corresponding to an integrated luminosity of 5.4 fb$^{-1}$, collected at a center-of-mass energy of $13$ TeV with the LHCb detector. A novel model-independent technique is used to compare the $D^+$ and $D^-$ phase-space distributions, with instrumental asymmetries subtracted using the $D^+_{s}\rightarrow K^-K^+\pi^+$ decay as a control channel. The $p$-value for the hypothesis of $C\!P$ conservation is $8.1\%$. The $C\!P$ asymmetry observables $A_{C\!P|S}^{\phi\pi^+} = (0.95 \pm 0.43_{stat} \pm 0.26_{syst})\times 10^{-3}$ and $A_{C\!P|S}^{\overline{K}^{*0}K^+} = (-0.26 \pm 0.56_{ stat} \pm 0.18_{syst})\times 10^{-3}$ are also measured. These results show no evidence of $C\!P$ violation and represent the most sensitive search performed through the phase space of a multibody decay., Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://lbfence.cern.ch/alcm/public/analysis/full-details/1616 (LHCb public pages)
- Published
- 2024
31. N-Way Joint Mutual Exclusion Does Not Imply Any Pairwise Mutual Exclusion for Propositions
- Author
-
Freedman, Roy S.
- Subjects
Computer Science - Discrete Mathematics - Abstract
Given a set of N propositions, if any pair is mutual exclusive, then the set of all propositions are N-way jointly mutually exclusive. This paper provides a new general counterexample to the converse. We prove that for any set of N propositional variables, there exist N propositions such that their N-way conjunction is zero, yet all k-way component conjunctions are non-zero. The consequence is that N-way joint mutual exclusion does not imply any pairwise mutual exclusion. A similar result is true for sets since propositional calculus and set theory are models for two-element Boolean algebra., Comment: 10 pages, 4 figures
- Published
- 2024
32. Study of the rare decay $J/\psi \to \mu^+\mu^-\mu^+\mu^-$
- Author
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LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataíde, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Balzani, L., Bao, H., Leite, J. Baptista de Souza, Pretel, C. Barbero, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bashir, S., Bassi, G., Batsukh, B., Battista, P. B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Behling, N. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bovill, M., Bowcock, T. J. V., Boyer, A., Bozzi, C., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Caillet, A. C., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Chang, X., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chiotopoulos, X., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Colonna, M. C., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. Curras, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Daniel, J., Danilina, A., d'Argent, P., Davidson, A., Davies, J. E., Davis, A., Francisco, O. De Aguiar, De Angelis, C., De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, P., De Vellis, F., de Vries, J. A., Debernardis, F., Decamp, D., Dedu, V., Del Buono, L., Delaney, B., Dembinski, H. -P., Deng, J., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Nezza, P., Diachkov, I., Didenko, S., Ding, S., Dittmann, L., Dobishuk, V., Docheva, A. D., Dong, C., Donohoe, A. M., Dordei, F., Reis, A. C. dos, Dowling, A. D., Duan, W., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Duras, M. M., Durham, J. M., Durmus, O. D., Dziurda, A., Dzyuba, A., Easo, S., Eckstein, E., Egede, U., Egorychev, A., Egorychev, V., Eisenhardt, S., Ejopu, E., Eklund, L., Elashri, M., Ellbracht, J., Ely, S., Ene, A., Epple, E., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farmer, K., Fazzini, D., Felkowski, L., Feng, M., Feo, M., Casani, A. Fernandez, Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Rodrigues, F. Ferreira, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Fischer, K. L., Fitzgerald, D. S., Fitzpatrick, C., Fleuret, F., Fontana, M., Foreman, L. F., Forty, R., Foulds-Holt, D., Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Fujii, Y., Fulghesu, T., Gabriel, E., Galati, G., Galati, M. D., Torreira, A. Gallas, Galli, D., Gambetta, S., Gandelman, M., Gandini, P., Ganie, B., Gao, H., Gao, R., Gao, Y., Garau, M., Martin, L. M. Garcia, Moreno, P. Garcia, Pardiñas, J. García, Garg, K. G., Garrido, L., Gaspar, C., Geertsema, R. E., Gerken, L. L., Gersabeck, E., Gersabeck, M., Gershon, T., Ghorbanimoghaddam, Z., Giambastiani, L., Giasemis, F. I., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Girardey, L., Gironell, P. Gironella, Giugliano, C., Giza, M. A., Gkougkousis, E. L., Glaser, F. C., Gligorov, V. V., Göbel, C., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Fernandez, S. Gomez, Abrantes, F. Goncalves, Goncerz, M., Gong, G., Gooding, J. A., Gorelov, I. V., Gotti, C., Grabowski, J. P., Cardoso, L. A. Granado, Graugés, E., Graverini, E., Grazette, L., Graziani, G., Grecu, A. T., Greeven, L. M., Grieser, N. A., Grillo, L., Gromov, S., Gu, C., Guarise, M., Guittiere, M., Guliaeva, V., Günther, P. A., Guseinov, A. -K., Gushchin, E., Guz, Y., Gys, T., Habermann, K., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Hajheidari, M., Hallett, G. H., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Han, Q., Han, X., Hansmann-Menzemer, S., Hao, L., Harnew, N., Hartmann, M., Hashmi, S., He, J., Hemmer, F., Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Gascon, P. Herrero, Heuel, J., Hicheur, A., Mendizabal, G. Hijano, Hill, D., Hollitt, S. E., Horswill, J., Hou, R., Hou, Y., Howarth, N., Hu, J., Hu, W., Hu, X., Huang, W., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., Jiang, Y. J., John, M., Rajan, A. John Rubesh, Johnson, D., Jones, C. R., Jones, T. P., Joshi, S., Jost, B., Castella, J. Juan, Jurik, N., Juszczak, I., Kaminaris, D., Kandybei, S., Kane, M., Kang, Y., Kar, C., Karacson, M., Karpenkov, D., Kauniskangas, A., Kautz, J. W., Keizer, F., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Khreich, G., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Kleijne, N., Klimaszewski, K., Kmiec, M. R., Koliiev, S., Kolk, L., Konoplyannikov, A., Kopciewicz, P., Koppenburg, P., Korolev, M., Kostiuk, I., Kot, O., Kotriakhova, S., Kozachuk, A., Kravchenko, P., Kravchuk, L., Kreps, M., Krokovny, P., Krupa, W., Krzemien, W., Kshyvanskyi, O. K., Kubat, J., Kubis, S., Kucharczyk, M., Kudryavtsev, V., Kulikova, E., Kupsc, A., Kutsenko, B. K., Lacarrere, D., Gonzalez, P. Laguarta, Lai, A., Lampis, A., Lancierini, D., Gomez, C. Landesa, Lane, J. J., Lane, R., Langenbruch, C., Langer, J., Lantwin, O., Latham, T., Lazzari, F., Lazzeroni, C., Gac, R. Le, Lee, H., Lefèvre, R., Leflat, A., Legotin, S., Lehuraux, M., Cid, E. Lemos, Leroy, O., Lesiak, T., Leverington, B., Li, A., Li, C., Li, H., Li, K., Li, L., Li, P., Li, P. -R., Li, Q., Li, S., Li, T., Li, Y., Lian, Z., Liang, X., Libralon, S., Lin, C., Lin, T., Lindner, R., Lisovskyi, V., Litvinov, R., Liu, F. L., Liu, G., Liu, K., Liu, S., Liu, W., Liu, Y., Liu, Y. L., Salvia, A. Lobo, Loi, A., Castro, J. Lomba, Long, T., Lopes, J. H., Huertas, A. Lopez, Soliño, S. López, Lucarelli, C., Lucchesi, D., Martinez, M. Lucio, Lukashenko, V., Luo, Y., Lupato, A., Luppi, E., Lynch, K., Lyu, X. -R., Ma, G. M., Ma, R., Maccolini, S., Machefert, F., Maciuc, F., Mack, B., Mackay, I., Mackey, L. M., Mohan, L. R. Madhan, Madurai, M. J., Maevskiy, A., Magdalinski, D., Maisuzenko, D., Majewski, M. W., Malczewski, J. J., Malde, S., Malentacca, L., Malinin, A., Maltsev, T., Manca, G., Mancinelli, G., Mancuso, C., Escalero, R. Manera, Manuzzi, D., Marangotto, D., Marchand, J. F., Marchevski, R., Marconi, U., Mariani, S., Benito, C. Marin, Marks, J., Marshall, A. M., Martel, L., Martelli, G., Martellotti, G., Martinazzoli, L., Martinelli, M., Santos, D. Martinez, Vidal, F. Martinez, Massafferri, A., Matev, R., Mathad, A., Matiunin, V., Matteuzzi, C., Mattioli, K. R., Mauri, A., Maurice, E., Mauricio, J., Mayencourt, P., de Cos, J. Mazorra, Mazurek, M., McCann, M., Mcconnell, L., McGrath, T. H., McHugh, N. T., McNab, A., McNulty, R., Meadows, B., Meier, G., Melnychuk, D., Meng, F. M., Merk, M., Merli, A., Garcia, L. Meyer, Miao, D., Miao, H., Mikhasenko, M., Milanes, D. A., Minotti, A., Minucci, E., Miralles, T., Mitreska, B., Mitzel, D. S., Modak, A., Mohammed, R. A., Moise, R. D., Mokhnenko, S., Mombächer, T., Monk, M., Monteil, S., Gomez, A. Morcillo, Morello, G., Morello, M. J., Morgenthaler, M. P., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Mu, Z. M., Muhammad, E., Muheim, F., Mulder, M., Müller, K., Muñoz-Rojas, F., Murta, R., Naik, P., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Nicolini, J., Nicotra, D., Niel, E. M., Nikitin, N., Nogarolli, P., Nogga, P., Nolte, N. S., Normand, C., Fernandez, J. Novoa, Nowak, G., Nunez, C., Nur, H. N., Oblakowska-Mucha, A., Obraztsov, V., Oeser, T., Okamura, S., Okhotnikov, A., Okhrimenko, O., Oldeman, R., Oliva, F., Olocco, M., Onderwater, C. J. G., O'Neil, R. H., Osthues, D., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Ozcelik, O., Padee, A., Padeken, K. O., Pagare, B., Pais, P. R., Pajero, T., Palano, A., Palutan, M., Panshin, G., Paolucci, L., Papanestis, A., Pappagallo, M., Pappalardo, L. L., Pappenheimer, C., Parkes, C., Passalacqua, B., Passaleva, G., Passaro, D., Pastore, A., Patel, M., Patoc, J., Patrignani, C., Paul, A., Pawley, C. J., Pellegrino, A., Peng, J., Altarelli, M. 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Rodriguez, Roensch, J., Rogachev, A., Rogovskiy, A., Rolf, D. L., Roloff, P., Romanovskiy, V., Lamas, M. Romero, Vidal, A. Romero, Romolini, G., Ronchetti, F., Rong, T., Rotondo, M., Roy, S. R., Rudolph, M. S., Diaz, M. Ruiz, Fernandez, R. A. Ruiz, Vidal, J. Ruiz, Ryzhikov, A., Ryzka, J., Saavedra-Arias, J. J., Silva, J. J. Saborido, Sadek, R., Sagidova, N., Sahoo, D., Sahoo, N., Saitta, B., Salomoni, M., Gras, C. Sanchez, Sanderswood, I., Santacesaria, R., Rios, C. Santamarina, Santimaria, M., Santoro, L., Santovetti, E., Saputi, A., Saranin, D., Sarnatskiy, A., Sarpis, G., Sarpis, M., Satriano, C., Satta, A., Saur, M., Savrina, D., Sazak, H., Smead, L. G. Scantlebury, Scarabotto, A., Schael, S., Scherl, S., Schiller, M., Schindler, H., Schmelling, M., Schmidt, B., Schmitt, S., Schmitz, H., Schneider, O., Schopper, A., Schulte, N., Schulte, S., Schune, M. H., Schwemmer, R., Schwering, G., Sciascia, B., Sciuccati, A., Sellam, S., Semennikov, A., Senger, T., Soares, M. 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- Subjects
High Energy Physics - Experiment - Abstract
The rare electromagnetic $J/\psi \to \mu^+\mu^-\mu^+\mu^-$ decay is observed with a significance greatly exceeding the discovery threshold, using proton-proton collision data collected by the LHCb experiment during 2016-2018 at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of $5.4\,\text{fb}^{-1}$. The rate of this decay is measured relative to that of the $J/\psi \to \mu^+\mu^-$ mode. Using the QED model for the four-muon decay in the efficiency estimation, its branching fraction is determined to be \begin{equation*} {\mathcal{B}}(J/\psi \to \mu^+\mu^-\mu^+\mu^-) = (1.13\pm0.10\pm0.05\pm0.01)\times 10^{-6}, \end{equation*} where the uncertainties are statistical, systematic and due to the uncertainty on the branching fraction of the $J/\psi \to \mu^+\mu^-$ decay., Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://lbfence.cern.ch/alcm/public/analysis/full-details/3453 (LHCb public pages)
- Published
- 2024
33. Observation of muonic Dalitz decays of $\chi_{b}$ mesons and precise spectroscopy of hidden-beauty states
- Author
-
LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataíde, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Balzani, L., Bao, H., Leite, J. Baptista de Souza, Pretel, C. Barbero, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bashir, S., Bassi, G., Batsukh, B., Battista, P. B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Behling, N. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Bordelius, A., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bovill, M., Bowcock, T. J. V., Boyer, A., Bozzi, C., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Caillet, A. C., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chiotopoulos, X., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Colonna, M. C., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. Curras, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Daniel, J., Danilina, A., d'Argent, P., Davidson, A., Davies, J. E., Davis, A., Francisco, O. De Aguiar, De Angelis, C., De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, P., De Vellis, F., de Vries, J. A., Debernardis, F., Decamp, D., Dedu, V., Dekkers, S., Del Buono, L., Delaney, B., Dembinski, H. -P., Deng, J., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Nezza, P., Diachkov, I., Didenko, S., Ding, S., Dittmann, L., Dobishuk, V., Docheva, A. D., Dong, C., Donohoe, A. M., Dordei, F., Reis, A. C. dos, Dowling, A. D., Duan, W., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Duras, M. M., Durham, J. M., Durmus, O. D., Dziurda, A., Dzyuba, A., Easo, S., Eckstein, E., Egede, U., Egorychev, A., Egorychev, V., Eisenhardt, S., Ejopu, E., Eklund, L., Elashri, M., Ellbracht, J., Ely, S., Ene, A., Epple, E., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farmer, K., Fazzini, D., Felkowski, L., Feng, M., Feo, M., Casani, A. Fernandez, Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Rodrigues, F. Ferreira, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Firlej, M., Fischer, K. L., Fitzgerald, D. S., Fitzpatrick, C., Fiutowski, T., Fleuret, F., Fontana, M., Foreman, L. F., Forty, R., Foulds-Holt, D., Lima, V. Franco, Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Fujii, Y., Fulghesu, T., Gabriel, E., Galati, G., Galati, M. D., Torreira, A. Gallas, Galli, D., Gambetta, S., Gandelman, M., Gandini, P., Ganie, B., Gao, H., Gao, R., Gao, T. Q., Gao, Y., Garau, M., Martin, L. M. Garcia, Moreno, P. Garcia, Pardiñas, J. García, Garg, K. G., Garrido, L., Gaspar, C., Geertsema, R. E., Gerken, L. L., Gersabeck, E., Gersabeck, M., Gershon, T., Ghizzo, S. G., Ghorbanimoghaddam, Z., Giambastiani, L., Giasemis, F. I., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Girardey, L., Gironell, P. Gironella, Giugliano, C., Giza, M. A., Gkougkousis, E. L., Glaser, F. C., Gligorov, V. V., Göbel, C., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Fernandez, S. Gomez, Abrantes, F. Goncalves, Goncerz, M., Gong, G., Gooding, J. A., Gorelov, I. V., Gotti, C., Grabowski, J. P., Cardoso, L. A. Granado, Graugés, E., Graverini, E., Grazette, L., Graziani, G., Grecu, A. T., Greeven, L. M., Grieser, N. A., Grillo, L., Gromov, S., Gu, C., Guarise, M., Guerry, L., Guittiere, M., Guliaeva, V., Günther, P. A., Guseinov, A. -K., Gushchin, E., Guz, Y., Gys, T., Habermann, K., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Hajheidari, M., Hallett, G. H., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Han, Q., Han, X., Hansmann-Menzemer, S., Hao, L., Harnew, N., Hartmann, M., Hashmi, S., He, J., Hemmer, F., Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Gascon, P. Herrero, Heuel, J., Hicheur, A., Mendizabal, G. Hijano, Hill, D., Hollitt, S. E., Horswill, J., Hou, R., Hou, Y., Howarth, N., Hu, J., Hu, W., Hu, X., Huang, W., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Idzik, M., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., Jiang, Y. J., John, M., Rajan, A. John Rubesh, Johnson, D., Jones, C. R., Jones, T. P., Joshi, S., Jost, B., Castella, J. Juan, Jurik, N., Juszczak, I., Kaminaris, D., Kandybei, S., Kane, M., Kang, Y., Kar, C., Karacson, M., Karpenkov, D., Kauniskangas, A., Kautz, J. W., Kazanecki, M. K., Keizer, F., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Khreich, G., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Kleijne, N., Klimaszewski, K., Kmiec, M. R., Koliiev, S., Kolk, L., Konoplyannikov, A., Kopciewicz, P., Koppenburg, P., Korolev, M., Kostiuk, I., Kot, O., Kotriakhova, S., Kozachuk, A., Kravchenko, P., Kravchuk, L., Kreps, M., Krokovny, P., Krupa, W., Krzemien, W., Kshyvanskyi, O. K., Kubis, S., Kucharczyk, M., Kudryavtsev, V., Kulikova, E., Kupsc, A., Kutsenko, B. K., Lacarrere, D., Gonzalez, P. Laguarta, Lai, A., Lampis, A., Lancierini, D., Gomez, C. Landesa, Lane, J. J., Lane, R., Lanfranchi, G., Langenbruch, C., Langer, J., Lantwin, O., Latham, T., Lazzari, F., Lazzeroni, C., Gac, R. 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M., Muhammad, E., Muheim, F., Mulder, M., Müller, K., Muñoz-Rojas, F., Murta, R., Naik, P., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Nicolini, J., Nicotra, D., Niel, E. M., Nikitin, N., Nogarolli, P., Nogga, P., Normand, C., Fernandez, J. Novoa, Nowak, G., Nunez, C., Nur, H. N., Oblakowska-Mucha, A., Obraztsov, V., Oeser, T., Okamura, S., Okhotnikov, A., Okhrimenko, O., Oldeman, R., Oliva, F., Olocco, M., Onderwater, C. J. G., O'Neil, R. H., Osthues, D., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Ozcelik, O., Paciolla, F., Padee, A., Padeken, K. O., Pagare, B., Pais, P. R., Pajero, T., Palano, A., Palutan, M., Panshin, G., Paolucci, L., Papanestis, A., Pappagallo, M., Pappalardo, L. L., Pappenheimer, C., Parkes, C., Passalacqua, B., Passaleva, G., Passaro, D., Pastore, A., Patel, M., Patoc, J., Patrignani, C., Paul, A., Pawley, C. J., Pellegrino, A., Peng, J., Altarelli, M. 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W., Wang, Y., Wang, Z., Ward, J. A., Waterlaat, M., Watson, N. K., Websdale, D., Wei, Y., Wendel, J., Westhenry, B. D. C., White, C., Whitehead, M., Whiter, E., Wiederhold, A. R., Wiedner, D., Wilkinson, G., Wilkinson, M. K., Williams, M., Williams, M. R. J., Williams, R., Williams, Z., Wilson, F. F., Wislicki, W., Witek, M., Witola, L., Wormser, G., Wotton, S. A., Wu, H., Wu, J., Wu, Y., Wu, Z., Wyllie, K., Xian, S., Xiang, Z., Xie, Y., Xu, A., Xu, J., Xu, L., Xu, M., Xu, Z., Yang, D., Yang, K., Yang, S., Yang, X., Yang, Y., Yang, Z., Yeroshenko, V., Yeung, H., Yin, H., Yu, C. Y., Yu, J., Yuan, X., Yuan, Y, Zaffaroni, E., Zavertyaev, M., Zdybal, M., Zenesini, F., Zeng, C., Zeng, M., Zhang, C., Zhang, D., Zhang, J., Zhang, L., Zhang, S., Zhang, Y., Zhang, Y. Z., Zhao, Y., Zharkova, A., Zhelezov, A., Zheng, S. Z., Zheng, X. Z., Zheng, Y., Zhou, T., Zhou, X., Zhou, Y., Zhovkovska, V., Zhu, L. Z., Zhu, X., Zhukov, V., Zhuo, J., Zou, Q., Zuliani, D., and Zunica, G.
- Subjects
High Energy Physics - Experiment - Abstract
The decays of the $\chi_{b1}(1P)$, $\chi_{b2}(1P)$, $\chi_{b1}(2P)$ and $\chi_{b2}(2P)$~mesons into the~$\Upsilon(1S)\mu^+\mu^-$ final state are observed with a high significance using proton-proton collision data collected with the LHCb detector and corresponding to an integrated luminosity of 9fb$^{-1}$. The newly observed decays together with the $\Upsilon(2S)\rightarrow \Upsilon(1S)\pi^+\pi^-$ and $\Upsilon(3S)\rightarrow \Upsilon(2S)\pi^+\pi^-$ decay modes are used for precision measurements of the mass and mass splittings for the hidden-beauty states., Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2024-025.html
- Published
- 2024
34. Measurement of $D^0-\overline{D}^0$ mixing and search for $CP$ violation with $D^0\rightarrow K^+\pi^-$ decays
- Author
-
LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataide, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Bao, H., Leite, J. Baptista de Souza, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bassi, G., Batsukh, B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bowcock, T. J. V., Boyer, A., Bozzi, C., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. Curras, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Daniel, J., Danilina, A., d'Argent, P., Davidson, A., Davies, J. E., Davis, A., Francisco, O. De Aguiar, De Angelis, C., De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, P., De Vellis, F., de Vries, J. A., Debernardis, F., Decamp, D., Dedu, V., Del Buono, L., Delaney, B., Dembinski, H. -P., Deng, J., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Nezza, P., Diachkov, I., Didenko, S., Ding, S., Dittmann, L., Dobishuk, V., Docheva, A. D., Dong, C., Donohoe, A. M., Dordei, F., Reis, A. C. dos, Dowling, A. D., Duan, W., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Duras, M. M., Durham, J. M., Durmus, O. D., Dziurda, A., Dzyuba, A., Easo, S., Eckstein, E., Egede, U., Egorychev, A., Egorychev, V., Eisenhardt, S., Ejopu, E., Eklund, L., Elashri, M., Ellbracht, J., Ely, S., Ene, A., Epple, E., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farmer, K., Fazzini, D., Felkowski, L., Feng, M., Feo, M., Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Rodrigues, F. Ferreira, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Fischer, K. M., Fitzgerald, D. S., Fitzpatrick, C., Fleuret, F., Fontana, M., Foreman, L. F., Forty, R., Foulds-Holt, D., Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Fujii, Y., Fulghesu, T., Gabriel, E., Galati, G., Galati, M. D., Torreira, A. Gallas, Galli, D., Gambetta, S., Gandelman, M., Gandini, P., Ganie, B., Gao, H., Gao, R., Gao, Y., Garau, M., Martin, L. M. Garcia, Moreno, P. Garcia, Pardiñas, J. García, Garg, K. G., Garrido, L., Gaspar, C., Geertsema, R. E., Gerken, L. L., Gersabeck, E., Gersabeck, M., Gershon, T., Ghorbanimoghaddam, Z., Giambastiani, L., Giasemis, F. I., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Gironell, P. Gironella, Giugliano, C., Giza, M. A., Gkougkousis, E. L., Glaser, F. C., Gligorov, V. V., Göbel, C., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Fernandez, S. Gomez, Abrantes, F. Goncalves, Goncerz, M., Gong, G., Gooding, J. A., Gorelov, I. V., Gotti, C., Grabowski, J. P., Cardoso, L. A. Granado, Graugés, E., Graverini, E., Grazette, L., Graziani, G., Grecu, A. T., Greeven, L. M., Grieser, N. A., Grillo, L., Gromov, S., Gu, C., Guarise, M., Guittiere, M., Guliaeva, V., Günther, P. A., Guseinov, A. -K., Gushchin, E., Guz, Y., Gys, T., Habermann, K., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Hajheidari, M., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Han, Q., Han, X., Hansmann-Menzemer, S., Hao, L., Harnew, N., Hartmann, M., He, J., Hemmer, F., Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Gascon, P. Herrero, Heuel, J., Hicheur, A., Mendizabal, G. Hijano, Hill, D., Hollitt, S. E., Horswill, J., Hou, R., Hou, Y., Howarth, N., Hu, J., Hu, W., Hu, X., Huang, W., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., Jiang, Y. J., John, M., Johnson, D., Jones, C. R., Jones, T. P., Joshi, S., Jost, B., Jurik, N., Juszczak, I., Kaminaris, D., Kandybei, S., Kang, Y., Kar, C., Karacson, M., Karpenkov, D., Kauniskangas, A., Kautz, J. W., Keizer, F., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Khreich, G., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Kleijne, N., Klimaszewski, K., Kmiec, M. R., Koliiev, S., Kolk, L., Konoplyannikov, A., Kopciewicz, P., Koppenburg, P., Korolev, M., Kostiuk, I., Kot, O., Kotriakhova, S., Kozachuk, A., Kravchenko, P., Kravchuk, L., Kreps, M., Krokovny, P., Krupa, W., Krzemien, W., Kshyvanskyi, O. K., Kubat, J., Kubis, S., Kucharczyk, M., Kudryavtsev, V., Kulikova, E., Kupsc, A., Kutsenko, B. K., Lacarrere, D., Lai, A., Lampis, A., Lancierini, D., Gomez, C. Landesa, Lane, J. J., Lane, R., Langenbruch, C., Langer, J., Lantwin, O., Latham, T., Lazzari, F., Lazzeroni, C., Gac, R. Le, Lefèvre, R., Leflat, A., Legotin, S., Lehuraux, M., Cid, E. Lemos, Leroy, O., Lesiak, T., Leverington, B., Li, A., Li, H., Li, K., Li, L., Li, P., Li, P. -R., Li, Q., Li, S., Li, T., Li, Y., Lian, Z., Liang, X., Libralon, S., Lin, C., Lin, T., Lindner, R., Lisovskyi, V., Litvinov, R., Liu, F. L., Liu, G., Liu, K., Liu, S., Liu, Y., Liu, Y. L., Salvia, A. Lobo, Loi, A., Castro, J. 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T., McNab, A., McNulty, R., Meadows, B., Meier, G., Melnychuk, D., Meng, F. M., Merk, M., Merli, A., Garcia, L. Meyer, Miao, D., Miao, H., Mikhasenko, M., Milanes, D. A., Minotti, A., Minucci, E., Miralles, T., Mitreska, B., Mitzel, D. S., Modak, A., Mödden, A., Mohammed, R. A., Moise, R. D., Mokhnenko, S., Mombächer, T., Monk, M., Monteil, S., Gomez, A. Morcillo, Morello, G., Morello, M. J., Morgenthaler, M. P., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Mu, Z. M., Muhammad, E., Muheim, F., Mulder, M., Müller, K., Muñoz-Rojas, F., Murta, R., Naik, P., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Nicolini, J., Nicotra, D., Niel, E. M., Nikitin, N., Nogarolli, P., Nogga, P., Nolte, N. S., Normand, C., Fernandez, J. Novoa, Nowak, G., Nunez, C., Nur, H. N., Oblakowska-Mucha, A., Obraztsov, V., Oeser, T., Okamura, S., Okhotnikov, A., Okhrimenko, O., Oldeman, R., Oliva, F., Olocco, M., Onderwater, C. J. 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- Subjects
High Energy Physics - Experiment - Abstract
A measurement of the time-dependent ratio of the $D^0\rightarrow K^+\pi^-$ to $\overline{D}^0\rightarrow K^+\pi^-$ decay rates is reported. The analysis uses a sample of proton-proton collisions corresponding to an integrated luminosity of 6 fb$^-1$ recorded by the LHCb experiment from 2015 through 2018 at a center-of-mass energy of 13 TeV. The $D^0$ meson is required to originate from a $D^{*+}\rightarrow D^0\pi^+$ decay, such that its flavor at production is inferred from the charge of the accompanying pion. The measurement is performed simultaneously for the $K^+\pi^-$ and $K^-\pi^+$ final states, allowing both mixing and $CP$-violation parameters to be determined. The value of the ratio of the decay rates at production is determined to be $R_{K\pi} = (343.1 \pm 2.0) \times 10^{-5}$. The mixing parameters are measured to be $c_{K\pi} = (51.4 \pm 3.5) \times 10^{-4}$ and $c_{K\pi}^{\prime} = (13 \pm 4) \times 10^{-6}$, where $\sqrt{R_{K\pi}}c_{K\pi}$ is the linear coefficient of the expansion of the ratio as a function of decay time in units of the $D^0$ lifetime, and $c_{K\pi}^{\prime}$ is the quadratic coefficient, both averaged between the $K^+\pi^-$ and $K^-\pi^+$ final states. The precision is improved relative to the previous best measurement by approximately 60%. No evidence for $CP$ violation is found., Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/Publications/LHCbProjectPublic/LHCb-PAPER-2024-008.html
- Published
- 2024
35. Observation of exotic $J/\psi\phi$ resonances in diffractive processes in proton-proton collisions
- Author
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LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Leite, J. Baptista de Souza, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Baryshnikov, F., Basels, J. M., Bassi, G., Batsukh, B., Battig, A., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Beiter, A., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertella, C., Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bowcock, T. J. V., Boyer, A., Bozzi, C., Bradley, M. J., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Bursche, A., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Calabrese, R., Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cerasoli, J., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. Curras, Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dai, X., Dall'Occo, E., Dalseno, J., D'Ambrosio, C., Daniel, J., Danilina, A., d'Argent, P., Davidson, A., Davies, J. E., Davis, A., Francisco, O. De Aguiar, De Angelis, C., De Benedetti, F., de Boer, J., De Bruyn, K., De Capua, S., De Cian, M., Da Graca, U. De Freitas Carneiro, De Lucia, E., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, D., De Simone, P., De Vellis, F., de Vries, J. A., Debernardis, F., Decamp, D., Dedu, V., Del Buono, L., Delaney, B., Dembinski, H. -P., Deng, J., Denysenko, V., Deschamps, O., Dettori, F., Dey, B., Di Nezza, P., Diachkov, I., Didenko, S., Ding, S., Dittmann, L., Dobishuk, V., Docheva, A. D., Dolmatov, A., Dong, C., Donohoe, A. M., Dordei, F., Reis, A. C. dos, Dowling, A. D., Downes, A. G., Duan, W., Duda, P., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Duras, M. M., Durham, J. M., Durmus, O. D., Dziurda, A., Dzyuba, A., Easo, S., Eckstein, E., Egede, U., Egorychev, A., Egorychev, V., Eisenhardt, S., Ejopu, E., Ek-In, S., Eklund, L., Elashri, M., Ellbracht, J., Ely, S., Ene, A., Epple, E., Escher, S., Eschle, J., Esen, S., Evans, T., Fabiano, F., Falcao, L. N., Fan, Y., Fang, B., Fantini, L., Faria, M., Farmer, K., Fazzini, D., Felkowski, L., Feng, M., Feo, M., Gomez, M. Fernandez, Fernez, A. D., Ferrari, F., Rodrigues, F. Ferreira, Sole, S. Ferreres, Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Fischer, K. M., Fitzgerald, D. S., Fitzpatrick, C., Fleuret, F., Fontana, M., Foreman, L. F., Forty, R., Foulds-Holt, D., Sevilla, M. Franco, Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Fujii, Y., Fulghesu, T., Gabriel, E., Galati, G., Galati, M. D., Torreira, A. Gallas, Galli, D., Gambetta, S., Gandelman, M., Gandini, P., Gao, H., Gao, R., Gao, Y., Garau, M., Martin, L. M. Garcia, Moreno, P. Garcia, Pardiñas, J. García, Garg, K. G., Garrido, L., Gaspar, C., Geertsema, R. E., Gerken, L. L., Gersabeck, E., Gersabeck, M., Gershon, T., Ghorbanimoghaddam, Z., Giambastiani, L., Giasemis, F. I., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Gironell, P. Gironella, Giugliano, C., Giza, M. A., Gkougkousis, E. L., Glaser, F. C., Gligorov, V. V., Göbel, C., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Fernandez, S. Gomez, Abrantes, F. Goncalves, Goncerz, M., Gong, G., Gooding, J. A., Gorelov, I. V., Gotti, C., Grabowski, J. P., Cardoso, L. A. Granado, Graugés, E., Graverini, E., Grazette, L., Graziani, G., Grecu, A. T., Greeven, L. M., Grieser, N. A., Grillo, L., Gromov, S., Gu, C., Guarise, M., Guittiere, M., Guliaeva, V., Günther, P. A., Guseinov, A. -K., Gushchin, E., Guz, Y., Gys, T., Habermann, K., Hadavizadeh, T., Hadjivasiliou, C., Haefeli, G., Haen, C., Haimberger, J., Hajheidari, M., Halvorsen, M. M., Hamilton, P. M., Hammerich, J., Han, Q., Han, X., Hansmann-Menzemer, S., Hao, L., Harnew, N., Harrison, T., Hartmann, M., He, J., Heijhoff, K., Hemmer, F., Henderson, C., Henderson, R. D. L., Hennequin, A. M., Hennessy, K., Henry, L., Herd, J., Gascon, P. Herrero, Heuel, J., Hicheur, A., Mendizabal, G. Hijano, Hill, D., Hollitt, S. E., Horswill, J., Hou, R., Hou, Y., Howarth, N., Hu, J., Hu, W., Hu, X., Huang, W., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Ilin, D., Ilten, P., Inglessi, A., Iniukhin, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jage, H., Elles, S. J. Jaimes, Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, E., Jiang, X., Jiang, Y., Jiang, Y. J., John, M., Johnson, D., Jones, C. R., Jones, T. P., Joshi, S., Jost, B., Jurik, N., Juszczak, I., Kaminaris, D., Kandybei, S., Kang, Y., Karacson, M., Karpenkov, D., Kauniskangas, A., Kautz, J. W., Keizer, F., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Khreich, G., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Kleijne, N., Klimaszewski, K., Kmiec, M. R., Koliiev, S., Kolk, L., Konoplyannikov, A., Kopciewicz, P., Koppenburg, P., Korolev, M., Kostiuk, I., Kot, O., Kotriakhova, S., Kozachuk, A., Kravchenko, P., Kravchuk, L., Kreps, M., Kretzschmar, S., Krokovny, P., Krupa, W., Krzemien, W., Kubat, J., Kubis, S., Kucewicz, W., Kucharczyk, M., Kudryavtsev, V., Kulikova, E., Kupsc, A., Kutsenko, B. K., Lacarrere, D., Lai, A., Lampis, A., Lancierini, D., Gomez, C. Landesa, Lane, J. J., Lane, R., Langenbruch, C., Langer, J., Lantwin, O., Latham, T., Lazzari, F., Lazzeroni, C., Gac, R. Le, Lefèvre, R., Leflat, A., Legotin, S., Lehuraux, M., Cid, E. Lemos, Leroy, O., Lesiak, T., Leverington, B., Li, A., Li, H., Li, K., Li, L., Li, P., Li, P. -R., Li, S., Li, T., Li, Y., Li, Z., Lian, Z., Liang, X., Libralon, S., Lin, C., Lin, T., Lindner, R., Lisovskyi, V., Litvinov, R., Liu, F. L., Liu, G., Liu, K., Liu, Q., Liu, S., Liu, Y., Liu, Y. L., Salvia, A. Lobo, Loi, A., Castro, J. Lomba, Long, T., Lopes, J. H., Huertas, A. Lopez, Soliño, S. López, Lovell, G. H., Lucarelli, C., Lucchesi, D., Luchuk, S., Martinez, M. Lucio, Lukashenko, V., Luo, Y., Lupato, A., Luppi, E., Lynch, K., Lyu, X. -R., Ma, G. M., Ma, R., Maccolini, S., Machefert, F., Maciuc, F., Mack, B., Mackay, I., Mackey, L. M., Mohan, L. R. Madhan, Madurai, M. M., Maevskiy, A., Magdalinski, D., Maisuzenko, D., Majewski, M. W., Malczewski, J. J., Malde, S., Malecki, B., Malentacca, L., Malinin, A., Maltsev, T., Manca, G., Mancinelli, G., Mancuso, C., Escalero, R. Manera, Manuzzi, D., Marangotto, D., Marchand, J. F., Marchevski, R., Marconi, U., Mariani, S., Benito, C. Marin, Marks, J., Marshall, A. M., Marshall, P. J., Martelli, G., Martellotti, G., Martinazzoli, L., Martinelli, M., Santos, D. Martinez, Vidal, F. Martinez, Massafferri, A., Materok, M., Matev, R., Mathad, A., Matiunin, V., Matteuzzi, C., Mattioli, K. R., Mauri, A., Maurice, E., Mauricio, J., Mayencourt, P., Mazurek, M., McCann, M., Mcconnell, L., McGrath, T. H., McHugh, N. T., McNab, A., McNulty, R., Meadows, B., Meier, G., Melnychuk, D., Merk, M., Merli, A., Garcia, L. Meyer, Miao, D., Miao, H., Mikhasenko, M., Milanes, D. A., Minotti, A., Minucci, E., Miralles, T., Mitreska, B., Mitzel, D. S., Modak, A., Mödden, A., Mohammed, R. A., Moise, R. D., Mokhnenko, S., Mombächer, T., Monk, M., Monteil, S., Gomez, A. Morcillo, Morello, G., Morello, M. J., Morgenthaler, M. P., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Mu, Z. M., Muhammad, E., Muheim, F., Mulder, M., Müller, K., Muñoz-Rojas, F., Murta, R., Naik, P., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Nicolini, J., Nicotra, D., Niel, E. M., Nikitin, N., Nogga, P., Nolte, N. S., Normand, C., Fernandez, J. Novoa, Nowak, G., Nunez, C., Nur, H. N., Oblakowska-Mucha, A., Obraztsov, V., Oeser, T., Okamura, S., Okhotnikov, A., Oldeman, R., Oliva, F., Olocco, M., Onderwater, C. J. G., O'Neil, R. H., Goicochea, J. M. Otalora, Owen, P., Oyanguren, A., Ozcelik, O., Padeken, K. O., Pagare, B., Pais, P. R., Pajero, T., Palano, A., Palutan, M., Panshin, G., Paolucci, L., Papanestis, A., Pappagallo, M., Pappalardo, L. L., Pappenheimer, C., Parkes, C., Passalacqua, B., Passaleva, G., Passaro, D., Pastore, A., Patel, M., Patoc, J., Patrignani, C., Pawley, C. J., Pellegrino, A., Altarelli, M. Pepe, Perazzini, S., Pereima, D., Castro, A. Pereiro, Perret, P., Perro, A., Petridis, K., Petrolini, A., Petrucci, S., Pfaller, J. P., Pham, H., Pica, L., Piccini, M., Pietrzyk, B., Pietrzyk, G., Pinci, D., Pisani, F., Pizzichemi, M., Placinta, V., Casasus, M. Plo, Polci, F., Lener, M. Poli, Poluektov, A., Polukhina, N., Polyakov, I., Polycarpo, E., Ponce, S., Popov, D., Poslavskii, S., Prasanth, K., Prouve, C., Pugatch, V., Punzi, G., Qian, W., Qin, N., Qu, S., Quagliani, R., Raab, N. V., Trejo, R. I. Rabadan, Rademacker, J. H., Rama, M., García, M. Ramírez, Pernas, M. Ramos, Rangel, M. S., Ratnikov, F., Raven, G., De Miguel, M. Rebollo, Redi, F., Reich, J., Reiss, F., Ren, Z., Resmi, P. K., Ribatti, R., Ricart, G. R., Riccardi, D., Ricciardi, S., Richardson, K., Richardson-Slipper, M., Rinnert, K., Robbe, P., Robertson, G., Rodrigues, E., Fernandez, E. Rodriguez, Lopez, J. A. Rodriguez, Rodriguez, E. Rodriguez, Rogovskiy, A., Rolf, D. L., Roloff, P., Romanovskiy, V., Lamas, M. Romero, Vidal, A. Romero, Romolini, G., Ronchetti, F., Rotondo, M., Roy, S. R., Rudolph, M. S., Ruf, T., Diaz, M. Ruiz, Fernandez, R. A. Ruiz, Vidal, J. Ruiz, Ryzhikov, A., Ryzka, J., Saavedra-Arias, J. J., Silva, J. J. Saborido, Sadek, R., Sagidova, N., Sahoo, D., Sahoo, N., Saitta, B., Salomoni, M., Gras, C. Sanchez, Sanderswood, I., Santacesaria, R., Rios, C. Santamarina, Santimaria, M., Santoro, L., Santovetti, E., Saputi, A., Saranin, D., Sarpis, G., Sarpis, M., Sarti, A., Satriano, C., Satta, A., Saur, M., Savrina, D., Sazak, H., Smead, L. G. Scantlebury, Scarabotto, A., Schael, S., Scherl, S., Schertz, A. M., Schiller, M., Schindler, H., Schmelling, M., Schmidt, B., Schmitt, S., Schmitz, H., Schneider, O., Schopper, A., Schulte, N., Schulte, S., Schune, M. H., Schwemmer, R., Schwering, G., Sciascia, B., Sciuccati, A., Sellam, S., Semennikov, A., Senger, T., Soares, M. Senghi, Sergi, A., Serra, N., Sestini, L., Seuthe, A., Shang, Y., Shangase, D. M., Shapkin, M., Sharma, R. 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- Subjects
High Energy Physics - Experiment - Abstract
The first study of $J/\psi\phi$ production in diffractive processes in proton-proton collisions is presented. The study is based on an LHCb dataset recorded at centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 5 fb$^{-1}$. The data disfavour a nonresonant $J/\psi\phi$ production but are consistent with a resonant model including several resonant states observed previously only in $B^+ \to J/\psi\phi K^+$ decays. The $\chi_{c0}(4500)$ state is observed with a significance over $5\sigma$ and the $\chi_{c1}(4274)$ is confirmed with a significance of more than $4\sigma$., Comment: All figures and tables, along with any supplementary material and additional information, are available at: https://lhcbproject.web.cern.ch/Publications/LHCbProjectPublic/LHCb-PAPER-2023-043.html (LHCb public pages)
- Published
- 2024
36. Study of charmonium production via the decay to $p\bar{p}$ at $\sqrt{s} = 13 TeV$
- Author
-
LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Bao, H., Leite, J. Baptista de Souza, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Baryshnikov, F., Basels, J. M., Bassi, G., Batsukh, B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bowcock, T. J. V., Boyer, A., Bozzi, C., Bradley, M. J., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. 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T., McNab, A., McNulty, R., Meadows, B., Meier, G., Melnychuk, D., Meng, F. M., Merk, M., Merli, A., Garcia, L. Meyer, Miao, D., Miao, H., Mikhasenko, M., Milanes, D. A., Minotti, A., Minucci, E., Miralles, T., Mitreska, B., Mitzel, D. S., Modak, A., Mödden, A., Mohammed, R. A., Moise, R. D., Mokhnenko, S., Mombächer, T., Monk, M., Monteil, S., Gomez, A. Morcillo, Morello, G., Morello, M. J., Morgenthaler, M. P., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Mu, Z. M., Muhammad, E., Muheim, F., Mulder, M., Müller, K., Muñoz-Rojas, F., Murta, R., Naik, P., Nakada, T., Nandakumar, R., Nanut, T., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neustroev, P., Nicolini, J., Nicotra, D., Niel, E. M., Nikitin, N., Nogarolli, P., Nogga, P., Nolte, N. S., Normand, C., Fernandez, J. Novoa, Nowak, G., Nunez, C., Nur, H. N., Oblakowska-Mucha, A., Obraztsov, V., Oeser, T., Okamura, S., Okhotnikov, A., Okhrimenko, O., Oldeman, R., Oliva, F., Olocco, M., Onderwater, C. J. 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Z., Zhao, Y., Zharkova, A., Zhelezov, A., Zheng, X. Z., Zheng, Y., Zhou, T., Zhou, X., Zhou, Y., Zhovkovska, V., Zhu, L. Z., Zhu, X., Zhukov, V., Zhuo, J., Zou, Q., Zuliani, D., and Zunica, G.
- Subjects
High Energy Physics - Experiment - Abstract
Charmonium production cross-section in proton-proton collisions is measured at the centre-of-mass energy $\sqrt{s}=13\,TeV$ using decays to $p\bar{p}$ final state. The study is performed using a data sample corresponding to an integrated luminosity of $2.2\,{fb}^{-1}$ collected in 2018 with the $LHCb$ detector. The production cross-section of the $\eta_c$ meson is measured in a rapidity range of $2.0 < y < 4.0$ and in a transverse momentum range of $5.0 < p_{T} < 20.0\,{GeV/\it{c}}$, which is extended compared with previous $LHCb$ analyses. The differential cross-section is measured in bins of $p_{T}$ and, for the first time, of $y$. Upper limits, at 90% and 95% confidence levels, on the $\eta_c(2S)$ and $h_c(1P)$ prompt production cross-sections are determined for the first time., Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2024-004.html (LHCb public pages)
- Published
- 2024
37. Room temperature Mott transistor based on resistive switching in disordered V2O3 films grown on Si
- Author
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De, Binoy Krishna, Sathe, V. G., Divya, Sharma, Pragati, Parate, Shubham Kumar, Kunwar, Hemant Singh, Nukala, Pavan, and Roy, S. B.
- Subjects
Condensed Matter - Materials Science ,Condensed Matter - Strongly Correlated Electrons - Abstract
Electric field-induced giant resistive switching triggered by insulator-to-metal transition (IMT) is one of the promising approaches for developing a new class of electronics often referred to as Mottronics. Achieving this resistive switching by minimal external field at room temperature is of paramount research and technological interest. Mott-IMT is often associated with structural modification, which is very important for optoelectronic and actuator applications. Here, we report a giant resistive switching of about 900 % at room temperature in disordered polycrystalline V2O3-Si thin film stabilized at the IMT phase boundary and associated structural transformation under a small electric field. The increase of electron population in the a1g band under the field is responsible for the Mott gap collapse that drives the structural transition. Furthermore, we also fabricated a room temperature Mott-FET with a channel ON/OFF resistive ratio of about 15. This study provides a fundamental mechanism of the Mott-IMT in V2O3 as well as its device applications., Comment: 16 pages, 5 figures
- Published
- 2024
38. Amplitude analysis of $B^+ \to \psi(2S) K^+ \pi^+ \pi^-$ decays
- Author
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LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Da Silva, R. Ataide, Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Balzani, L., Bao, H., Leite, J. Baptista de Souza, Pretel, C. Barbero, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Basels, J. M., Bashir, S., Bassi, G., Batsukh, B., Battista, P. B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Behling, N. B., Belin, S., Bellee, V., Belous, K., Belov, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bovill, M., Bowcock, T. J. V., Boyer, A., Bozzi, C., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Caillet, A. C., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Chatzianagnostou, E., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chiotopoulos, X., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Colonna, M. 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- Subjects
High Energy Physics - Experiment - Abstract
The first full amplitude analysis of $B^+ \to \psi(2S) K^+ \pi^+ \pi^-$ decays is performed using proton-proton collision data corresponding to an integrated luminosity of $9\,\text{fb}^{-1}$ recorded with the LHCb detector. The rich $K^+ \pi^+ \pi^-$ spectrum is studied and the branching fractions of the resonant substructure associated with the prominent $K_1(1270)^+$ contribution are measured. The data cannot be described by conventional strange and charmonium resonances only. An amplitude model with 53 components is developed comprising 11 hidden-charm exotic hadrons. New production mechanisms for charged charmonium-like states are observed. Significant resonant activity with spin-parity $J^P = 1^+$ in the $\psi(2S) \pi^+$ system is confirmed and a multi-pole structure is demonstrated. The spectral decomposition of the $\psi(2S) \pi^+ \pi^-$ invariant-mass structure, dominated by $X^0 \to \psi(2S) \rho(770)^0$ decays, broadly resembles the $J/\psi \phi$ spectrum observed in $B^+ \to J/\psi \phi K^+$ decays. Exotic $\psi(2S) K^+ \pi^-$ resonances are observed for the first time., Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2024-014.html (LHCb public pages)
- Published
- 2024
39. Search for the rare $\Lambda_c^+ \to p \mu^+ \mu^-$ decay
- Author
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LHCb collaboration, Aaij, R., Abdelmotteleb, A. S. W., Beteta, C. Abellan, Abudinén, F., Ackernley, T., Adefisoye, A. A., Adeva, B., Adinolfi, M., Adlarson, P., Agapopoulou, C., Aidala, C. A., Ajaltouni, Z., Akar, S., Akiba, K., Albicocco, P., Albrecht, J., Alessio, F., Alexander, M., Aliouche, Z., Cartelle, P. Alvarez, Amalric, R., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andersson, M., Andreianov, A., Andreola, P., Andreotti, M., Andreou, D., Anelli, A., Ao, D., Archilli, F., Argenton, M., Cuendis, S. Arguedas, Artamonov, A., Artuso, M., Aslanides, E., Atzeni, M., Audurier, B., Bacher, D., Perea, I. Bachiller, Bachmann, S., Bachmayer, M., Back, J. J., Rodriguez, P. Baladron, Balagura, V., Baldini, W., Bao, H., Leite, J. Baptista de Souza, Barbetti, M., Barbosa, I. R., Barlow, R. J., Barnyakov, M., Barsuk, S., Barter, W., Bartolini, M., Bartz, J., Baryshnikov, F., Basels, J. M., Bassi, G., Batsukh, B., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I. B., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Benane, G., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Andres, S. Bernet, Bertolin, A., Betancourt, C., Betti, F., Bex, J., Bezshyiko, Ia., Bhom, J., Bieker, M. S., Biesuz, N. V., Billoir, P., Biolchini, A., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blank, J. E., Blusk, S., Bocharnikov, V., Boelhauve, J. A., Garcia, O. Boente, Boettcher, T., Bohare, A., Boldyrev, A., Bolognani, C. S., Bolzonella, R., Bondar, N., Borgato, F., Borghi, S., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bowcock, T. J. V., Boyer, A., Bozzi, C., Bradley, M. J., Rodriguez, A. Brea, Breer, N., Brodzicka, J., Gonzalo, A. Brossa, Brown, J., Brundu, D., Buchanan, E., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Calabrese, R., Ramirez, S. Calderon, Calefice, L., Cali, S., Calvi, M., Gomez, M. Calvo, Magalhaes, P. Camargo, Bouzas, J. I. Cambon, Campana, P., Perez, D. H. Campora, Quezada, A. F. Campoverde, Capelli, S., Capriotti, L., Caravaca-Mora, R., Carbone, A., Salgado, L. Carcedo, Cardinale, R., Cardini, A., Carniti, P., Carus, L., Vidal, A. Casais, Caspary, R., Casse, G., Godinez, J. Castro, Cattaneo, M., Cavallero, G., Cavallini, V., Celani, S., Cervenkov, D., Cesare, S., Chadwick, A. J., Chahrour, I., Charles, M., Charpentier, Ph., Barajas, C. A. Chavez, Chefdeville, M., Chen, C., Chen, S., Chen, Z., Chernov, A., Chernyshenko, S., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Vidal, X. Cid, Ciezarek, G., Cifra, P., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Toapaxi, C. Cocha, Coco, V., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Comerma-Montells, A., Congedo, L., Contu, A., Cooke, N., Corredoira, I., Correia, A., Corti, G., Meldrum, J. J. Cottee, Couturier, B., Craik, D. C., Torres, M. Cruz, Rivera, E. 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Ramírez, De Oliveira, V. Ramos, Pernas, M. Ramos, Rangel, M. S., Ratnikov, F., Raven, G., De Miguel, M. Rebollo, Redi, F., Reich, J., Reiss, F., Ren, Z., Resmi, P. K., Ribatti, R., Ricart, G. R., Riccardi, D., Ricciardi, S., Richardson, K., Richardson-Slipper, M., Rinnert, K., Robbe, P., Robertson, G., Rodrigues, E., Fernandez, E. Rodriguez, Lopez, J. A. Rodriguez, Rodriguez, E. Rodriguez, Rogovskiy, A., Rolf, D. L., Roloff, P., Romanovskiy, V., Lamas, M. Romero, Vidal, A. Romero, Romolini, G., Ronchetti, F., Rotondo, M., Roy, S. R., Rudolph, M. S., Ruf, T., Diaz, M. Ruiz, Fernandez, R. A. Ruiz, Vidal, J. Ruiz, Ryzhikov, A., Ryzka, J., Saavedra-Arias, J. J., Silva, J. J. Saborido, Sadek, R., Sagidova, N., Sahoo, D., Sahoo, N., Saitta, B., Salomoni, M., Gras, C. Sanchez, Sanderswood, I., Santacesaria, R., Rios, C. Santamarina, Santimaria, M., Santoro, L., Santovetti, E., Saputi, A., Saranin, D., Sarpis, G., Sarpis, M., Satriano, C., Satta, A., Saur, M., Savrina, D., Sazak, H., Smead, L. G. Scantlebury, Scarabotto, A., Schael, S., Scherl, S., Schiller, M., Schindler, H., Schmelling, M., Schmidt, B., Schmitt, S., Schmitz, H., Schneider, O., Schopper, A., Schulte, N., Schulte, S., Schune, M. H., Schwemmer, R., Schwering, G., Sciascia, B., Sciuccati, A., Sellam, S., Semennikov, A., Senger, T., Soares, M. Senghi, Sergi, A., Serra, N., Sestini, L., Seuthe, A., Shang, Y., Shangase, D. M., Shapkin, M., Sharma, R. S., Shchemerov, I., Shchutska, L., Shears, T., Shekhtman, L., Shen, Z., Sheng, S., Shevchenko, V., Shi, B., Shi, Q., Shields, E. B., Shimizu, Y., Shmanin, E., Shorkin, R., Shupperd, J. D., Coutinho, R. Silva, Simi, G., Simone, S., Skidmore, N., Skwarnicki, T., Slater, M. W., Smallwood, J. C., Smith, E., Smith, K., Smith, M., Snoch, A., Lavra, L. Soares, Sokoloff, M. D., Soler, F. J. 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High Energy Physics - Experiment - Abstract
A search for the nonresonant $\Lambda_c^+ \to p \mu^+ \mu^-$ decay is performed using proton-proton collision data recorded at a centre-of-mass energy of 13 TeV by the LHCb experiment, corresponding to an integrated luminosity of 5.4 fb$^{-1}$. No evidence for the decay is found in the dimuon invariant-mass regions where the expected contributions of resonances is subdominant. The upper limit on the branching fraction of the $\Lambda_c^+ \to p \mu^+ \mu^-$ decay is determined to be $2.9~(3.2) \times 10^{-8}$ at 90% (95%) confidence level. The branching fractions in the dimuon invariant-mass regions dominated by the $\eta$, $\rho$ and $\omega$ resonances are also determined., Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2024-005.html (LHCb public pages)
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- 2024
40. Effect of ground-state deformation on the Isoscalar Giant Monopole Resonance and the first observation of overtones of the Isoscalar Giant Quadrupole Resonance in rare-earth Nd isotopes
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Abdullah, M., Bagchi, S., Harakeh, M. N., Akimune, H., Das, D., Doi, T., Donaldson, L. M., Fujikawa, Y., Fujiwara, M., Furuno, T., Garg, U., Gupta, Y. K., Howard, K. B., Hijikata, Y., Inaba, K., Ishida, S., Itoh, M., Kalantar-Nayestanaki, N., Kar, D., Kawabata, T., Kawashima, S., Khokhar, K., Kitamura, K., Kobayashi, N., Matsuda, Y., Nakagawa, A., Nakamura, S., Nosaka, K., Okamoto, S., Ota, S., Pal, S., Pramanik, R., Roy, S., Weyhmiller, S., Yang, Z., and Zamora, J. C.
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Nuclear Experiment ,Nuclear Theory - Abstract
The strength distributions of the Isoscalar Giant Monopole Resonance (ISGMR) and Isoscalar Giant Quadrupole Resonance (ISGQR) in 142,146-150Nd have been determined via inelastic alpha-particle scattering with the Grand Raiden (GR) Spectrometer at the Research Center for Nuclear Physics (RCNP), Japan. In the deformed nuclei 146-150Nd, the ISGMR strength distributions exhibit a splitting into two components, while the nearly spherical nucleus 142Nd displays a single peak in the ISGMR strength distribution. A noteworthy achievement in this study is the first-time detection of overtones in the Isoscalar Giant Quadrupole Resonance (ISGQR) strength distributions within Nd isotopes at an excitation energy around 25 MeV obtained through Multipole Decomposition Analysis (MDA)., Comment: Accepted for publication in Physics Letters B
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- 2024
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41. Maximizing the value of phase III trials in immuno-oncology: A checklist from the Society for Immunotherapy of Cancer (SITC)
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James L Gulley, James Larkin, Leisha A Emens, Mario Sznol, Madhav Dhodapkar, Daniel S Chen, Roy S Herbst, Tim F Greten, Robert L Ferris, Luca Mazzarella, Paolo A Ascierto, Marc S Ernstoff, Michael B Atkins, Kim A Margolin, Brian I Rini, Michael R Bishop, Suresh S Ramalingam, Meredith M Regan, and Rachel W Humphrey
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
The broad activity of agents blocking the programmed cell death protein 1 and its ligand (the PD-(L)1 axis) revolutionized oncology, offering long-term benefit to patients and even curative responses for tumors that were once associated with dismal prognosis. However, only a minority of patients experience durable clinical benefit with immune checkpoint inhibitor monotherapy in most disease settings. Spurred by preclinical and correlative studies to understand mechanisms of non-response to the PD-(L)1 antagonists and by combination studies in animal tumor models, many drug development programs were designed to combine anti-PD-(L)1 with a variety of approved and investigational chemotherapies, tumor-targeted therapies, antiangiogenic therapies, and other immunotherapies. Several immunotherapy combinations improved survival outcomes in a variety of indications including melanoma, lung, kidney, and liver cancer, among others. This immunotherapy renaissance, however, has led to many combinations being advanced to late-stage development without definitive predictive biomarkers, limited phase I and phase II data, or clinical trial designs that are not optimized for demonstrating the unique attributes of immune-related antitumor activity—for example, landmark progression-free survival and overall survival. The decision to activate a study at an individual site is investigator-driven, and generalized frameworks to evaluate the potential for phase III trials in immuno-oncology to yield positive data, particularly to increase the number of curative responses or otherwise advance the field have thus far been lacking. To assist in evaluating the potential value to patients and the immunotherapy field of phase III trials, the Society for Immunotherapy of Cancer (SITC) has developed a checklist for investigators, described in this manuscript. Although the checklist focuses on anti-PD-(L)1-based combinations, it may be applied to any regimen in which immune modulation is an important component of the antitumor effect.
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- 2022
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42. Spatially resolved proteomic profiling identifies tumor cell CD44 as a biomarker associated with sensitivity to PD-1 axis blockade in advanced non-small-cell lung cancer
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Luis M Montuenga, Roy S Herbst, Luis Paz-Ares, David L Rimm, Kurt A Schalper, Alfonso Calvo, Myrto K Moutafi, Ioannis A Vathiotis, Magdalena Molero, Sandra Martinez Morilla, Javier Baena, Niki Gavrielatou, Laura Castro-Labrador, Gorka Ruiz de Garibay, Vera Adradas, Daniel Orive, Karmele Valencia, S Ponce Aix, and Jon Zugazagoitia
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background Most patients with advanced non-small-cell lung cancer (NSCLC) fail to derive significant benefit from programmed cell death protein-1 (PD-1) axis blockade, and new biomarkers of response are needed. In this study, we aimed to discover and validate spatially resolved protein markers associated with sensitivity to PD-1 axis inhibition in NSCLC.Methods We initially assessed a discovery cohort of 56 patients with NSCLC treated with PD-1 axis inhibitors at Yale Cancer Center. Using the GeoMx Digital Spatial Profiling (DSP) system, 71 proteins were measured in spatial context on each spot in a tissue microarray. We used the AQUA method of quantitative immunofluorescence (QIF) to orthogonally validate candidate biomarkers. For external independent validation, we assessed whole tissue sections derived from 128 patients with NSCLC treated with single-agent PD-1 axis inhibitors at the 12 de Octubre Hospital (Madrid) using DSP. We further analyzed two immunotherapy untreated cohorts to address prognostic significance (n=252 from Yale Cancer Center; n=124 from University Clinic of Navarra) using QIF and DSP, respectively.Results Using continuous log-scaled data, we identified CD44 expression in the tumor compartment (pan-cytokeratin (CK)+) as a novel predictor of prolonged progression-free survival (PFS) (multivariate HR=0.68, p=0.043) in the discovery set. We validated by QIF that tumor CD44 levels assessed as continuous QIF scores were associated with longer PFS (multivariate HR=0.31, p=0.022) and overall survival (multivariate HR=0.29, p=0.038). Using DSP in an independent immunotherapy treated cohort, we validated that CD44 levels in the tumor compartment, but not in the immune compartment (panCK–/CD45+), were associated with clinical benefit (OR=1.22, p=0.018) and extended PFS under PD-1 axis inhibition using the highest tertile cutpoint (multivariate HR=0.62, p=0.03). The effect of tumor cell CD44 in predicting PFS remained significant after correcting for programmed death-ligand 1 (PD-L1) Tumor Proportion Score (TPS) in both cohorts. High tumor cell CD44 was not prognostic in the absence of immunotherapy. Using DSP data, intratumoral regions with elevated tumor cell CD44 expression showed prominent (fold change>1.5, adjusted p
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- 2022
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43. Addressing CPI resistance in NSCLC: targeting TAM receptors to modulate the tumor microenvironment and future prospects
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Solange Peters, Roy S Herbst, Martin Reck, and Luis Paz-Ares
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Lung cancer remains a leading cause of cancer death worldwide, with non-small-cell lung cancer (NSCLC) accounting for the majority of cases. Immune checkpoint inhibitors (CPIs), including those targeting programmed cell death protein-1 and its ligand (PD-1/PD-L1), have revolutionized the treatment landscape for various cancers. Notably, PD-1/PD-L1 inhibitor-based regimens now form the standard first-line therapy for metastatic NSCLC, substantially improving patients’ overall survival. Despite the progress made using CPI-based therapies in advanced NSCLC, most patients experience disease progression after an initial response due to resistance. Given the currently limited therapeutic options available for second-line and beyond settings in NSCLC, new treatment approaches are needed to improve long-term survival in these patients. Thus, CPI resistance is an emerging concept in cancer treatment and an active area of clinical research.Among the key mechanisms of CPI resistance is the immunosuppressive tumor microenvironment (TME). Effective CPI therapy is based on shifting immune responses against cancer cells, therefore, manipulating the immunosuppressive TME comprises an important strategy to combat CPI resistance. Several aspects of the TME can contribute to treatment resistance in NSCLC, including through the activation of Tyro3, Axl, MerTK (TAM) receptors which are essential pleiotropic regulators of immune homeostasis. Their roles include negatively modulating the immune response, therefore ectopic expression of TAM receptors in the context of cancer can contribute to the immunosuppressive, protumorigenic TME. Furthermore, TAM receptors represent important candidates to simultaneously target both tumor cells and immune cells in the TME. Clinical development of TAM receptor inhibitors (TAM RIs) is increasingly focused on their ability to rescue the antitumor immune response, thereby shifting the immunosuppressive TME to an immunostimulatory TME. There is a strong biological rationale for combining TAM RIs with a CPI to overcome resistance and improve long-term clinical responses in NSCLC. Combinatorial clinical trials of TAM RIs with CPIs are underway with encouraging preliminary results. This review outlines the key mechanisms of CPI resistance, including the role of the immunosuppressive TME, and discusses the rationale for targeting TAM receptors as a novel, promising therapeutic strategy to overcome CPI resistance in NSCLC.
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- 2022
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44. Quantitative tissue analysis and role of myeloid cells in non-small cell lung cancer
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Roy S Herbst, Lieping Chen, David L Rimm, Miguel F Sanmamed, Kurt A Schalper, Alice Li, Konstantinos Syrigos, Jovian Yu, Adam Aguirre-Ducler, Brian S Henick, Franz Villarroel-Espindola, Ila Datar, and Shruti Desai
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background Despite the prominent role of innate immunity in the antitumor response, little is known about the myeloid composition of human non-small cell lung cancer (NSCLC) with respect to histology and molecular subtype. We used multiplexed quantitative immunofluorescence (QIF) to measure the distribution and clinical significance of major myeloid cell subsets in large retrospective NSCLC collections.Methods We established a QIF panel to map major myeloid cell subsets in fixed human NSCLC including 4’,6-Diamidino-2-Phenylindole for all cells, pancytokeratin for tumor-epithelial cells, CD68 for M1-like macrophages; and CD11b plus HLA-DR to interrogate mature and immature myeloid cell populations such as myeloid derived suppressor cells (MDSCs). We interrogated 793 NSCLCs represented in four tissue microarray-based cohorts: #1 (Yale, n=379) and #2 (Greece, n=230) with diverse NSCLC subtypes; #3 (Yale, n=138) with molecularly annotated lung adenocarcinomas (ADC); and #4 (Yale, n=46) with patient-matched NSCLC and morphologically-normal lung tissue. We examined associations between marker levels, myeloid cell profiles, clinicopathologic/molecular variables and survival.Results The levels of CD68+ M1 like macrophages were significantly lower and the fraction of CD11b+/HLA-DR− MDSC-like cells was prominently higher in tumor than in matched non-tumor lung tissues. HLA-DR was consistently higher in myeloid cells from tumors with elevated CD68 expression. Stromal CD11b was significantly higher in squamous cell carcinomas (SCC) than in ADC across the cohorts and EGFR-mutated lung ADCs displayed lower CD11b levels than KRAS-mutant tumors. Increased stromal CD68- and HLA-DR-expressing cells was associated with better survival in ADCs from two independent NSCLC cohorts. In SCC, increased stromal CD11b or HLA-DR expression was associated with a trend towards shorter 5-year survival.Conclusions NSCLCs display an unfavorable myeloid immune contexture relative to non-tumor lung and exhibit distinct myeloid-cell profiles across histologies and presence of major oncogenic driver-mutations. Elevated M1-like stromal proinflammatory myeloid cells are prognostic in lung ADC, but not in SCC.
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- 2022
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45. Observation of Gravitational Waves from the Coalescence of a $2.5\text{-}4.5~M_\odot$ Compact Object and a Neutron Star
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The LIGO Scientific Collaboration, the Virgo Collaboration, the KAGRA Collaboration, Abac, A. G., Abbott, R., Abouelfettouh, I., Acernese, F., Ackley, K., Adhicary, S., Adhikari, N., Adhikari, R. X., Adkins, V. K., Agarwal, D., Agathos, M., Abchouyeh, M. Aghaei, Aguiar, O. D., Aguilar, I., Aiello, L., Ain, A., Ajith, P., Akçay, S., Akutsu, T., Albanesi, S., Alfaidi, R. A., Al-Jodah, A., Alléné, C., Allocca, A., Al-Shammari, S., Altin, P. A., Alvarez-Lopez, S., Amato, A., Amez-Droz, L., Amorosi, A., Amra, C., Ananyeva, A., Anderson, S. B., Anderson, W. G., Andia, M., Ando, M., Andrade, T., Andres, N., Andrés-Carcasona, M., Andrić, T., Anglin, J., Ansoldi, S., Antelis, J. M., Antier, S., Aoumi, M., Appavuravther, E. Z., Appert, S., Apple, S. K., Arai, K., Araya, A., Araya, M. C., Areeda, J. S., Argianas, L., Aritomi, N., Armato, F., Arnaud, N., Arogeti, M., Aronson, S. M., Arun, K. G., Ashton, G., Aso, Y., Assiduo, M., Melo, S. Assis de Souza, Aston, S. M., Astone, P., Attadio, F., Aubin, F., AultONeal, K., Avallone, G., Azrad, D., Babak, S., Badaracco, F., Badger, C., Bae, S., Bagnasco, S., Bagui, E., Baier, J. G., Baiotti, L., Bajpai, R., Baka, T., Ball, M., Ballardin, G., Ballmer, S. W., Banagiri, S., Banerjee, B., Bankar, D., Baral, P., Barayoga, J. C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartoletti, A. M., Barton, M. A., Bartos, I., Basak, S., Basalaev, A., Bassiri, R., Basti, A., Bates, D. E., Bawaj, M., Baxi, P., Bayley, J. C., Baylor, A. C., Baynard II, P. A., Bazzan, M., Bedakihale, V. M., Beirnaert, F., Bejger, M., Belardinelli, D., Bell, A. S., Benedetto, V., Benoit, W., Bentara, I., Bentley, J. D., Yaala, M. Ben, Bera, S., Berbel, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Beroiz, M., Berry, C. P. L., Bersanetti, D., Bertolini, A., Betzwieser, J., Beveridge, D., Bevins, N., Bhandare, R., Bhardwaj, U., Bhatt, R., Bhattacharjee, D., Bhaumik, S., Bhowmick, S., Bianchi, A., Bilenko, I. A., Billingsley, G., Binetti, A., Bini, S., Birnholtz, O., Biscoveanu, S., Bisht, A., Bitossi, M., Bizouard, M. -A., Blackburn, J. K., Blagg, L. A., Blair, C. D., Blair, D. G., Bobba, F., Bode, N., Boileau, G., Boldrini, M., Bolingbroke, G. N., Bolliand, A., Bonavena, L. D., Bondarescu, R., Bondu, F., Bonilla, E., Bonilla, M. S., Bonino, A., Bonnand, R., Booker, P., Borchers, A., Boschi, V., Bose, S., Bossilkov, V., Boudart, V., Boudon, A., Bozzi, A., Bradaschia, C., Brady, P. R., Braglia, M., Branch, A., Branchesi, M., Brandt, J., Braun, I., Breschi, M., Briant, T., Brillet, A., Brinkmann, M., Brockill, P., Brockmueller, E., Brooks, A. F., Brown, B. C., Brown, D. D., Brozzetti, M. L., Brunett, S., Bruno, G., Bruntz, R., Bryant, J., Bucci, F., Buchanan, J., Bulashenko, O., Bulik, T., Bulten, H. J., Buonanno, A., Burtnyk, K., Buscicchio, R., Buskulic, D., Buy, C., Byer, R. L., Davies, G. S. Cabourn, Cabras, G., Cabrita, R., Cáceres-Barbosa, V., Cadonati, L., Cagnoli, G., Cahillane, C., Bustillo, J. Calderón, Callister, T. A., Calloni, E., Camp, J. B., Canepa, M., Santoro, G. Caneva, Cannon, K. C., Cao, H., Capistran, L. A., Capocasa, E., Capote, E., Carapella, G., Carbognani, F., Carlassara, M., Carlin, J. B., Carpinelli, M., Carrillo, G., Carter, J. J., Carullo, G., Diaz, J. Casanueva, Casentini, C., Castro-Lucas, S. Y., Caudill, S., Cavaglià, M., Cavalieri, R., Cella, G., Cerdá-Durán, P., Cesarini, E., Chaibi, W., Chakraborty, P., Subrahmanya, S. Chalathadka, Chan, J. C. L., Chan, M., Chandra, K., Chang, R. -J., Chao, S., Char, P., Charlton, E. L., Charlton, P., Chassande-Mottin, E., Chatterjee, C., Chatterjee, Debarati, Chatterjee, Deep, Chattopadhyay, D., Chaturvedi, M., Chaty, S., Chatziioannou, K., Chen, A., Chen, A. H. -Y., Chen, D., Chen, H., Chen, H. 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G., Crook, S., Crouch, R., Csizmazia, J., Cudell, J. R., Cullen, T. J., Cumming, A., Cuoco, E., Cusinato, M., Dabadie, P., Canton, T. Dal, Dall'Osso, S., Pra, S. Dal, Dálya, G., D'Angelo, B., Danilishin, S., D'Antonio, S., Danzmann, K., Darroch, K. E., Dartez, L. P., Dasgupta, A., Datta, S., Dattilo, V., Daumas, A., Davari, N., Dave, I., Davenport, A., Davier, M., Davies, T. F., Davis, D., Davis, L., Davis, M. C., Davis, P. J., Dax, M., De Bolle, J., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deléglise, S., De Lillo, F., Dell'Aquila, D., Del Pozzo, W., De Marco, F., De Matteis, F., D'Emilio, V., Demos, N., Dent, T., Depasse, A., DePergola, N., De Pietri, R., De Rosa, R., De Rossi, C., DeSalvo, R., De Simone, R., Dhani, A., Diab, R., Díaz, M. C., Di Cesare, M., Dideron, G., Didio, N. A., Dietrich, T., Di Fiore, L., Di Fronzo, C., Di Giovanni, M., Di Girolamo, T., Diksha, D., Di Michele, A., Ding, J., Di Pace, S., Di Palma, I., Di Renzo, F., Divyajyoti, Dmitriev, A., Doctor, Z., Dohmen, E., Doleva, P. P., Dominguez, D., D'Onofrio, L., Donovan, F., Dooley, K. L., Dooney, T., Doravari, S., Dorosh, O., Drago, M., Driggers, J. C., Ducoin, J. -G., Dunn, L., Dupletsa, U., D'Urso, D., Duval, H., Duverne, P. -A., Dwyer, S. E., Eassa, C., Ebersold, M., Eckhardt, T., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Eichholz, J., Einsle, H., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Eleveld, R. M., Emma, M., Endo, K., Engl, A. J., Enloe, E., Errico, L., Essick, R. C., Estellés, H., Estevez, D., Etzel, T., Evans, M., Evstafyeva, T., Ewing, B. E., Ezquiaga, J. M., Fabrizi, F., Faedi, F., Fafone, V., Fairhurst, S., Farah, A. M., Farr, B., Farr, W. M., Favaro, G., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Felicetti, R., Fenyvesi, E., Ferguson, D. L., Ferraiuolo, S., Ferrante, I., Ferreira, T. A., Fidecaro, F., Figura, P., Fiori, A., Fiori, I., Fishbach, M., Fisher, R. P., Fittipaldi, R., Fiumara, V., Flaminio, R., Fleischer, S. M., Fleming, L. S., Floden, E., Foley, E. M., Fong, H., Font, J. A., Fornal, B., Forsyth, P. W. F., Franceschetti, K., Franchini, N., Frasca, S., Frasconi, F., Mascioli, A. Frattale, Frei, Z., Freise, A., Freitas, O., Frey, R., Frischhertz, W., Fritschel, P., Frolov, V. V., Fronzé, G. G., Fuentes-Garcia, M., Fujii, S., Fujimori, T., Fulda, P., Fyffe, M., Gadre, B., Gair, J. R., Galaudage, S., Galdi, V., Gallagher, H., Gallardo, S., Gallego, B., Gamba, R., Gamboa, A., Ganapathy, D., Ganguly, A., Garaventa, B., García-Bellido, J., Núñez, C. García, García-Quirós, C., Gardner, J. W., Gardner, K. A., Gargiulo, J., Garron, A., Garufi, F., Gasbarra, C., Gateley, B., Gayathri, V., Gemme, G., Gennai, A., Gennari, V., George, J., George, R., Gerberding, O., Gergely, L., Ghonge, S., Ghosh, Archisman, Ghosh, Sayantan, Ghosh, Shaon, Ghosh, Shrobana, Ghosh, Suprovo, Ghosh, Tathagata, Giacoppo, L., Giaime, J. A., Giardina, K. D., Gibson, D. R., Gibson, D. T., Gier, C., Giri, P., Gissi, F., Gkaitatzis, S., Glanzer, J., Glotin, F., Godfrey, J., Godwin, P., Goebbels, N. L., Goetz, E., Golomb, J., Lopez, S. Gomez, Goncharov, B., Gong, Y., González, G., Goodarzi, P., Goode, S., Goodwin-Jones, A. W., Gosselin, M., Göttel, A. S., Gouaty, R., Gould, D. W., Govorkova, K., Goyal, S., Grace, B., Grado, A., Graham, V., Granados, A. E., Granata, M., Granata, V., Gras, S., Grassia, P., Gray, A., Gray, C., Gray, R., Greco, G., Green, A. C., Green, S. M., Green, S. R., Gretarsson, A. M., Gretarsson, E. M., Griffith, D., Griffiths, W. L., Griggs, H. L., Grignani, G., Grimaldi, A., Grimaud, C., Grote, H., Guerra, D., Guetta, D., Guidi, G. M., Guimaraes, A. R., Gulati, H. K., Gulminelli, F., Gunny, A. M., Guo, H., Guo, W., Guo, Y., Gupta, Anchal, Gupta, Anuradha, Gupta, Ish, Gupta, N. C., Gupta, P., Gupta, S. K., Gupta, T., Gupte, N., Gurs, J., Gutierrez, N., Guzman, F., H, H. -Y., Haba, D., Haberland, M., Haino, S., Hall, E. D., Hamilton, E. Z., Hammond, G., Han, W. -B., Haney, M., Hanks, J., Hanna, C., Hannam, M. D., Hannuksela, O. A., Hanselman, A. G., Hansen, H., Hanson, J., Harada, R., Hardison, A. R., Haris, K., Harmark, T., Harms, J., Harry, G. M., Harry, I. W., Hart, J., Haskell, B., Haster, C. -J., Hathaway, J. S., Haughian, K., Hayakawa, H., Hayama, K., Hayes, R., Heffernan, A., Heidmann, A., Heintze, M. C., Heinze, J., Heinzel, J., Heitmann, H., Hellman, F., Hello, P., Helmling-Cornell, A. F., Hemming, G., Henderson-Sapir, O., Hendry, M., Heng, I. S., Hennes, E., Henshaw, C., Hertog, T., Heurs, M., Hewitt, A. 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O., Macquet, A., Macri, D., Maeda, K., Maenaut, S., Hernandez, I. Magaña, Magare, S. S., Magazzù, C., Magee, R. M., Maggio, E., Maggiore, R., Magnozzi, M., Mahesh, M., Mahesh, S., Maini, M., Majhi, S., Majorana, E., Makarem, C. N., Makelele, E., Malaquias-Reis, J. A., Mali, U., Maliakal, S., Malik, A., Man, N., Mandic, V., Mangano, V., Mannix, B., Mansell, G. L., Mansingh, G., Manske, M., Mantovani, M., Mapelli, M., Marchesoni, F., Pina, D. Marín, Marion, F., Márka, S., Márka, Z., Markosyan, A. S., Markowitz, A., Maros, E., Marsat, S., Martelli, F., Martin, I. W., Martin, R. M., Martinez, B. B., Martinez, M., Martinez, V., Martini, A., Martinovic, K., Martins, J. C., Martynov, D. V., Marx, E. J., Massaro, L., Masserot, A., Masso-Reid, M., Mastrodicasa, M., Mastrogiovanni, S., Matcovich, T., Matiushechkina, M., Matsuyama, M., Mavalvala, N., Maxwell, N., McCarrol, G., McCarthy, R., McClelland, D. E., McCormick, S., McCuller, L., McEachin, S., McElhenny, C., McGhee, G. I., McGinn, J., McGowan, K. B. M., McIver, J., McLeod, A., McRae, T., Meacher, D., Meijer, Q., Melatos, A., Mellaerts, S., Menendez-Vazquez, A., Menoni, C. S., Mera, F., Mercer, R. A., Mereni, L., Merfeld, K., Merilh, E. L., Mérou, J. R., Merritt, J. D., Merzougui, M., Messenger, C., Messick, C., Meyer-Conde, M., Meylahn, F., Mhaske, A., Miani, A., Miao, H., Michaloliakos, I., Michel, C., Michimura, Y., Middleton, H., Miller, A. L., Miller, S., Millhouse, M., Milotti, E., Milotti, V., Minenkov, Y., Mio, N., Mir, Ll. M., Mirasola, L., Miravet-Tenés, M., Miritescu, C. -A., Mishra, A. K., Mishra, A., Mishra, C., Mishra, T., Mitchell, A. L., Mitchell, J. G., Mitra, S., Mitrofanov, V. P., Mittleman, R., Miyakawa, O., Miyamoto, S., Miyoki, S., Mo, G., Mobilia, L., Mohapatra, S. R. P., Mohite, S. R., Molina-Ruiz, M., Mondal, C., Mondin, M., Montani, M., Moore, C. J., Moraru, D., More, A., More, S., Moreno, G., Morgan, C., Morisaki, S., Moriwaki, Y., Morras, G., Moscatello, A., Mourier, P., Mours, B., Mow-Lowry, C. M., Muciaccia, F., Mukherjee, Arunava, Mukherjee, D., Mukherjee, Samanwaya, Mukherjee, Soma, Mukherjee, Subroto, Mukherjee, Suvodip, Mukund, N., Mullavey, A., Munch, J., Mundi, J., Mungioli, C. L., Oberg, W. R. Munn, Murakami, Y., Murakoshi, M., Murray, P. G., Muusse, S., Nabari, D., Nadji, S. L., Nagar, A., Nagarajan, N., Nagler, K. N., Nakagaki, K., Nakamura, K., Nakano, H., Nakano, M., Nandi, D., Napolano, V., Narayan, P., Nardecchia, I., Narikawa, T., Narola, H., Naticchioni, L., Nayak, R. K., Neilson, J., Nelson, A., Nelson, T. J. N., Nery, M., Neunzert, A., Ng, S., Quynh, L. Nguyen, Nichols, S. A., Nielsen, A. B., Nieradka, G., Niko, A., Nishino, Y., Nishizawa, A., Nissanke, S., Nitoglia, E., Niu, W., Nocera, F., Norman, M., North, C., Novak, J., Siles, J. F. Nuño, Nuttall, L. K., Obayashi, K., Oberling, J., O'Dell, J., Oertel, M., Offermans, A., Oganesyan, G., Oh, J. J., Oh, K., O'Hanlon, T., Ohashi, M., Ohkawa, M., Ohme, F., Oliveira, A. S., Oliveri, R., O'Neal, B., Oohara, K., O'Reilly, B., Ormsby, N. D., Orselli, M., O'Shaughnessy, R., O'Shea, S., Oshima, Y., Oshino, S., Ossokine, S., Osthelder, C., Ota, I., Ottaway, D. J., Ouzriat, A., Overmier, H., Owen, B. J., Pace, A. E., Pagano, R., Page, M. A., Pai, A., Pal, A., Pal, S., Palaia, M. A., Pálfi, M., Palma, P. P., Palomba, C., Palud, P., Pan, H., Pan, J., Pan, K. C., Panai, R., Panda, P. K., Pandey, S., Panebianco, L., Pang, P. T. H., Pannarale, F., Pannone, K. A., Pant, B. C., Panther, F. H., Paoletti, F., Paolone, A., Papalexakis, E. E., Papalini, L., Papigkiotis, G., Paquis, A., Parisi, A., Park, B. -J., Park, J., Parker, W., Pascale, G., Pascucci, D., Pasqualetti, A., Passaquieti, R., Passenger, L., Passuello, D., Patane, O., Pathak, D., Pathak, M., Patra, A., Patricelli, B., Patron, A. S., Paul, K., Paul, S., Payne, E., Pearce, T., Pedraza, M., Pegna, R., Pele, A., Arellano, F. E. Peña, Penn, S., Penuliar, M. D., Perego, A., Pereira, Z., Perez, J. J., Périgois, C., Perna, G., Perreca, A., Perret, J., Perriès, S., Perry, J. W., Pesios, D., Petracca, S., Petrillo, C., Pfeiffer, H. P., Pham, H., Pham, K. A., Phukon, K. S., Phurailatpam, H., Piarulli, M., Piccari, L., Piccinni, O. J., Pichot, M., Piendibene, M., Piergiovanni, F., Pierini, L., Pierra, G., Pierro, V., Pietrzak, M., Pillas, M., Pilo, F., Pinard, L., Pinto, I. M., Pinto, M., Piotrzkowski, B. J., Pirello, M., Pitkin, M. D., Placidi, A., Placidi, E., Planas, M. L., Plastino, W., Poggiani, R., Polini, E., Pompili, L., Poon, J., Porcelli, E., Porter, E. K., Posnansky, C., Poulton, R., Powell, J., Pracchia, M., Pradhan, B. K., Pradier, T., Prajapati, A. K., Prasai, K., Prasanna, R., Prasia, P., Pratten, G., Principe, G., Principe, M., Prodi, G. A., Prokhorov, L., Prosposito, P., Puecher, A., Pullin, J., Punturo, M., Puppo, P., Pürrer, M., Qi, H., Qin, J., Quéméner, G., Quetschke, V., Quigley, C., Quinonez, P. J., Raab, F. J., Raabith, S. S., Raaijmakers, G., Raja, S., Rajan, C., Rajbhandari, B., Ramirez, K. E., Vidal, F. A. Ramis, Ramos-Buades, A., Rana, D., Ranjan, S., Ransom, K., Rapagnani, P., Ratto, B., Rawat, S., Ray, A., Raymond, V., Razzano, M., Read, J., Payo, M. Recaman, Regimbau, T., Rei, L., Reid, S., Reitze, D. H., Relton, P., Renzini, A. I., Rettegno, P., Revenu, B., Reyes, R., Rezaei, A. S., Ricci, F., Ricci, M., Ricciardone, A., Richardson, J. W., Richardson, M., Rijal, A., Riles, K., Riley, H. K., Rinaldi, S., Rittmeyer, J., Robertson, C., Robinet, F., Robinson, M., Rocchi, A., Rolland, L., Rollins, J. G., Romano, A. E., Romano, R., Romero, A., Romero-Shaw, I. M., Romie, J. H., Ronchini, S., Roocke, T. J., Rosa, L., Rosauer, T. J., Rose, C. A., Rosińska, D., Ross, M. P., Rossello, M., Rowan, S., Roy, S. K., Roy, S., Rozza, D., Ruggi, P., Ruhama, N., Morales, E. Ruiz, Ruiz-Rocha, K., Sachdev, S., Sadecki, T., Sadiq, J., Saffarieh, P., Sah, M. R., Saha, S. S., Saha, S., Sainrat, T., Menon, S. Sajith, Sakai, K., Sakellariadou, M., Sakon, S., Salafia, O. S., Salces-Carcoba, F., Salconi, L., Saleem, M., Salemi, F., Sallé, M., Salvador, S., Sanchez, A., Sanchez, E. J., Sanchez, J. H., Sanchez, L. E., Sanchis-Gual, N., Sanders, J. R., Sänger, E. M., Santoliquido, F., Saravanan, T. R., Sarin, N., Sasaoka, S., Sasli, A., Sassi, P., Sassolas, B., Satari, H., Sathyaprakash, B. S., Sato, R., Sato, Y., Sauter, O., Savage, R. L., Sawada, T., Sawant, H. L., Sayah, S., Scacco, V., Schaetzl, D., Scheel, M., Schiebelbein, A., Schiworski, M. G., Schmidt, P., Schmidt, S., Schnabel, R., Schneewind, M., Schofield, R. M. S., Schouteden, K., Schulte, B. W., Schutz, B. F., Schwartz, E., Scialpi, M., Scott, J., Scott, S. M., Seetharamu, T. C., Seglar-Arroyo, M., Sekiguchi, Y., Sellers, D., Sengupta, A. S., Sentenac, D., Seo, E. G., Seo, J. W., Sequino, V., Serra, M., Servignat, G., Sevrin, A., Shaffer, T., Shah, U. S., Shaikh, M. A., Shao, L., Sharma, A. K., Sharma, P., Sharma-Chaudhary, S., Shaw, M. R., Shawhan, P., Shcheblanov, N. S., Sheridan, E., Shikano, Y., Shikauchi, M., Shimode, K., Shinkai, H., Shiota, J., Shoemaker, D. H., Shoemaker, D. M., Short, R. W., ShyamSundar, S., Sider, A., Siegel, H., Sieniawska, M., Sigg, D., Silenzi, L., Simmonds, M., Singer, L. P., Singh, A., Singh, D., Singh, M. K., Singh, S., Singha, A., Sintes, A. M., Sipala, V., Skliris, V., Slagmolen, B. J. J., Slaven-Blair, T. J., Smetana, J., Smith, J. R., Smith, L., Smith, R. J. E., Smith, W. J., Soldateschi, J., Somiya, K., Song, I., Soni, K., Soni, S., Sordini, V., Sorrentino, F., Sorrentino, N., Sotani, H., Soulard, R., Southgate, A., Spagnuolo, V., Spencer, A. P., Spera, M., Spinicelli, P., Spoon, J. B., Sprague, C. A., Srivastava, A. K., Stachurski, F., Steer, D. A., Steinlechner, J., Steinlechner, S., Stergioulas, N., Stevens, P., Stevenson, S., StPierre, M., Stratta, G., Strong, M. D., Strunk, A., Sturani, R., Stuver, A. L., Suchenek, M., Sudhagar, S., Sueltmann, N., Suleiman, L., Sullivan, K. D., Sun, L., Sunil, S., Suresh, J., Sutton, P. J., Suzuki, T., Suzuki, Y., Swinkels, B. L., Syx, A., Szczepańczyk, M. J., Szewczyk, P., Tacca, M., Tagoshi, H., Tait, S. C., Takahashi, H., Takahashi, R., Takamori, A., Takase, T., Takatani, K., Takeda, H., Takeshita, K., Talbot, C., Tamaki, M., Tamanini, N., Tanabe, D., Tanaka, K., Tanaka, S. J., Tanaka, T., Tang, D., Tanioka, S., Tanner, D. B., Tao, L., Tapia, R. D., Martín, E. N. Tapia San, Tarafder, R., Taranto, C., Taruya, A., Tasson, J. D., Teloi, M., Tenorio, R., Themann, H., Theodoropoulos, A., Thirugnanasambandam, M. P., Thomas, L. M., Thomas, M., Thomas, P., Thompson, J. E., Thondapu, S. R., Thorne, K. A., Thrane, E., Tissino, J., Tiwari, A., Tiwari, P., Tiwari, S., Tiwari, V., Todd, M. R., Toivonen, A. M., Toland, K., Tolley, A. E., Tomaru, T., Tomita, K., Tomura, T., Tong, H., Tong-Yu, C., Toriyama, A., Toropov, N., Torres-Forné, A., Torrie, C. I., Toscani, M., Melo, I. Tosta e, Tournefier, E., Trapananti, A., Travasso, F., Traylor, G., Trevor, M., Tringali, M. C., Tripathee, A., Troian, G., Troiano, L., Trovato, A., Trozzo, L., Trudeau, R. J., Tsang, T. T. L., Tsuchida, S., Tsukada, L., Tsutsui, T., Turbang, K., Turconi, M., Turski, C., Ubach, H., Uchikata, N., Uchiyama, T., Udall, R. P., Uehara, T., Uematsu, M., Ueno, K., Ueno, S., Undheim, V., Ushiba, T., Vacatello, M., Vahlbruch, H., Vaidya, N., Vajente, G., Vajpeyi, A., Valdes, G., Valencia, J., Valentini, M., Vallejo-Peña, S. A., Vallero, S., Valsan, V., van Bakel, N., van Beuzekom, M., van Dael, M., Brand, J. F. J. van den, Broeck, C. Van Den, Vander-Hyde, D. C., van der Sluys, M., Van de Walle, A., van Dongen, J., Vandra, K., van Haevermaet, H., van Heijningen, J. V., Van Hove, P., VanKeuren, M., Vanosky, J., van Putten, M. H. P. M., van Ranst, Z., van Remortel, N., Vardaro, M., Vargas, A. F., Varghese, J. J., Varma, V., Vecchio, A., Vedovato, G., Veitch, J., Veitch, P. J., Venikoudis, S., Venneberg, J., Verdier, P., Verkindt, D., Verma, B., Verma, P., Verma, Y., Vermeulen, S. M., Vetrano, F., Veutro, A., Vibhute, A. M., Viceré, A., Vidyant, S., Viets, A. D., Vijaykumar, A., Vilkha, A., Villa-Ortega, V., Vincent, E. T., Vinet, J. -Y., Viret, S., Virtuoso, A., Vitale, S., Vives, A., Vocca, H., Voigt, D., von Reis, E. R. G., von Wrangel, J. S. A., Vyatchanin, S. P., Wade, L. E., Wade, M., Wagner, K. J., Wajid, A., Walker, M., Wallace, G. S., Wallace, L., Wang, H., Wang, J. Z., Wang, W. H., Wang, Z., Waratkar, G., Warner, J., Was, M., Washimi, T., Washington, N. Y., Watarai, D., Wayt, K. E., Weaver, B. R., Weaver, B., Weaving, C. R., Webster, S. A., Weinert, M., Weinstein, A. J., Weiss, R., Wellmann, F., Wen, L., Weßels, P., Wette, K., Whelan, J. T., Whiting, B. F., Whittle, C., Wildberger, J. B., Wilk, O. S., Wilken, D., Wilkin, A. T., Willadsen, D. J., Willetts, K., Williams, D., Williams, M. J., Williams, N. S., Willis, J. L., Willke, B., Wils, M., Winterflood, J., Wipf, C. C., Woan, G., Woehler, J., Wofford, J. K., Wolfe, N. E., Wong, H. T., Wong, H. W. Y., Wong, I. C. F., Wright, J. L., Wright, M., Wu, C., Wu, D. S., Wu, H., Wuchner, E., Wysocki, D. M., Xu, V. A., Xu, Y., Yadav, N., Yamamoto, H., Yamamoto, K., Yamamoto, T. S., Yamamoto, T., Yamamura, S., Yamazaki, R., Yan, S., Yan, T., Yang, F. W., Yang, F., Yang, K. Z., Yang, Y., Yarbrough, Z., Yasui, H., Yeh, S. -W., Yelikar, A. B., Yin, X., Yokoyama, J., Yokozawa, T., Yoo, J., Yu, H., Yuan, S., Yuzurihara, H., Zadrożny, A., Zanolin, M., Zeeshan, M., Zelenova, T., Zendri, J. -P., Zeoli, M., Zerrad, M., Zevin, M., Zhang, A. C., Zhang, L., Zhang, R., Zhang, T., Zhang, Y., Zhao, C., Zhao, Yue, Zhao, Yuhang, Zheng, Y., Zhong, H., Zhou, R., Zhu, X. -J., Zhu, Z. -H., Zimmerman, A. B., Zucker, M. E., and Zweizig, J.
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Astrophysics - High Energy Astrophysical Phenomena ,General Relativity and Quantum Cosmology - Abstract
We report the observation of a coalescing compact binary with component masses $2.5\text{-}4.5~M_\odot$ and $1.2\text{-}2.0~M_\odot$ (all measurements quoted at the 90% credible level). The gravitational-wave signal GW230529_181500 was observed during the fourth observing run of the LIGO-Virgo-KAGRA detector network on 2023 May 29 by the LIGO Livingston Observatory. The primary component of the source has a mass less than $5~M_\odot$ at 99% credibility. We cannot definitively determine from gravitational-wave data alone whether either component of the source is a neutron star or a black hole. However, given existing estimates of the maximum neutron star mass, we find the most probable interpretation of the source to be the coalescence of a neutron star with a black hole that has a mass between the most massive neutron stars and the least massive black holes observed in the Galaxy. We provisionally estimate a merger rate density of $55^{+127}_{-47}~\text{Gpc}^{-3}\,\text{yr}^{-1}$ for compact binary coalescences with properties similar to the source of GW230529_181500; assuming that the source is a neutron star-black hole merger, GW230529_181500-like sources constitute about 60% of the total merger rate inferred for neutron star-black hole coalescences. The discovery of this system implies an increase in the expected rate of neutron star-black hole mergers with electromagnetic counterparts and provides further evidence for compact objects existing within the purported lower mass gap., Comment: 45 pages (10 pages author list, 13 pages main text, 1 page acknowledgements, 13 pages appendices, 8 pages bibliography), 17 figures, 16 tables. Update to match version published in The Astrophysical Journal Letters. Data products available from https://zenodo.org/records/10845779
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- 2024
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46. Ambient Melting Behavior of Stoichiometric Uranium-Plutonium Mixed Oxide Fuel
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Leonid Burakovsky, Scott D. Ramsey, and Roy S. Baty
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actinide oxides ,mixed oxide (MOX) ,phase diagram ,melting curve ,shear modulus ,materials modeling ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Mixed oxides of uranium and plutonium (MOX) are currently considered as a reference fuel for the new generation of fast breeder reactors such as ASTRID. The key factor determining the performance and safety of a fuel such as MOX is its operational limits in the application environment which are closely related to the material’s structure and thermodynamic stability. They are in turn closely related to the ambient (zero pressure) melting point (Tm); thus, Tm is an important engineering parameter. Furthermore, PuO2 and UO2 are two endpoints of the phase diagram of MOX; therefore, their ambient Tms are fundamental reference points. However, the current knowledge of the Tm of MOX is limited and controversial as several studies available in the literature do not converge on the unique behavior of Tm as a function of x. Specifically, some studies produced Tm as a monotonically decreasing function of x such that, with Tm of UO2(x=0) of 3150 K, Tm of PuO2(x=1) is ∼2650 K, while other studies resulted in Tm having a local minimum at 0.5
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- 2023
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47. Multiparameter diagnostic sensor measurements during clinically stable periods and worsening heart failure in ambulatory patients
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Roy S. Gardner, Pramodsingh Thakur, Eric F. Hammill, Devi G. Nair, Zayd Eldadah, Branislav Stančák, Kevin Ferrick, Charn Sriratanasathavorn, Gábor Zoltán Duray, Ramesh Wariar, Yi Zhang, Qi An, Viktoria Averina, and John P. Boehmer
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Heart failure ,CRT ,Prognostication ,Ambulatory monitoring ,Decompensation ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims This study aims to characterize the range of implantable device‐based sensor values including heart sounds, markers of ventilation, thoracic impedance, activity, and heart rate for patients with heart failure (HF) when patients were deemed to be in clinically stable periods against the time course of acute decompensation and recovery from HF events. Methods and results The MultiSENSE trial followed 900 patients implanted with a COGNIS CRT‐D for up to 1 year. Chronic, ambulatory diagnostic sensor data were collected and evaluated during clinically stable periods (CSP: unchanged NYHA classification, no adverse events, and weight change ≤2.27 kg), and in the timeframe leading up to and following HF events (HF admissions or unscheduled visits with intravenous HF treatment). Physiologic sensor data from 1667 CSPs occurring in 676 patients were compared with those data leading up to and following 192 HF events in 106 patients. Overall, the mean age was 66.6 years, and the population were predominantly male (73%). Patients were primarily in NYHA II (67%), with a mean LVEF of 29.6% and median NT‐proBNP of 754.5 pg/mL. Sensor values during CSP were poorer in patients who had HF events during the study period than those without HF events, including first heart sound (S1: 2.18 ± 0.84 mG vs. 2.62 ± 0.95 mG, P = 0.002), third heart sound (S3: 1.13 ± 0.36 mG vs. 0.91 ± 0.30 mG, P
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- 2021
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48. Real‐world outcomes in cardiac resynchronization therapy patients: design and baseline demographics of the SMART‐ Registry
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Roy S. Gardner, Antonio D'Onofrio, George Mark, Daniel Gras, Yan Hu, Sara Veraghtert, and Ignacio Garcia‐Bolao
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Heart failure ,Left ventricular systolic dysfunction ,CRT ,Prognosis ,Registry ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims The SMART (Strategic MAnagement to optimize response to cardiac Resynchronization Therapy) Registry was designed to assess real‐world outcomes for patients receiving a cardiac resynchronization therapy defibrillator (CRT‐D) and to better understand which programming and optimization techniques are used and how effective they are. Methods and results The SMART Registry is a global, multicentre, prospective, observational, post‐market CRT‐D registry with a planned enrolment of 2000 subjects from a maximum of 200 sites in Europe, North America, and Asia‐Pacific region. Each subject will be followed up for a minimum of 12 months. The primary endpoint of CRT response rate at 12 months is defined by a clinical composite score of all‐cause mortality, heart failure events, New York Heart Association Class, and quality of life as assessed by a patient global assessment instrument. A subgroup composed of the first 103 consecutive European subjects implanted with an NG4 device will have left ventricular multisite pacing feature enabled at any time during the initial 12 months of follow‐up. The primary endpoint for this sub‐analysis will be the NG4 PG‐related complication‐free rate at 36 months. Conclusions The SMART Registry achieved its recruitment target in August 2019, with 2014 patients enrolled. The baseline demographics demonstrated that patients were generally older, with greater co‐morbidity, and on more contemporary medical therapy than in the key CRT trials. The results of the SMART Registry will determine which programming and optimization techniques are effective in this real‐world population.
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- 2021
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49. Role of tumor infiltrating lymphocytes and spatial immune heterogeneity in sensitivity to PD-1 axis blockers in non-small cell lung cancer
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Roy S Herbst, Vamsidhar Velcheti, Mari Mino-Kenudson, Matthew D Hellmann, David L Rimm, Kurt A Schalper, Anant Madabhushi, Justin Gainor, Germán Corredor, Miguel Lopez de Rodas, Venkata Nagineni, Arvind Ravi, Ila J Datar, Cristian Barrera, Lindsey Behlman, and Jonathan W Riess
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2022
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50. Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma
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Raffit Hassan, Patrick M Forde, Edward B Garon, Steven M Dubinett, Roy S Herbst, Charu Aggarwal, Matthew D Hellmann, Sarah B Goldberg, David L Rimm, Sarah Sagorsky, Boris Sepesi, Ramaswamy Govindan, Andrea Ferris, Scott J Antonia, Fred R Hirsch, Lawrence H Schwartz, Marianne Davies, Melissa L Johnson, Shakun Malik, Daniel Morgensztern, Joel W Neal, and Jyoti D Patel
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Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Immunotherapy has transformed lung cancer care in recent years. In addition to providing durable responses and prolonged survival outcomes for a subset of patients with heavily pretreated non-small cell lung cancer (NSCLC), immune checkpoint inhibitors (ICIs)— either as monotherapy or in combination with other ICIs or chemotherapy—have demonstrated benefits in first-line therapy for advanced disease, the neoadjuvant and adjuvant settings, as well as in additional thoracic malignancies such as small-cell lung cancer (SCLC) and mesothelioma. Challenging questions remain, however, on topics including therapy selection, appropriate biomarker-based identification of patients who may derive benefit, the use of immunotherapy in special populations such as people with autoimmune disorders, and toxicity management. Patient and caregiver education and support for quality of life (QOL) is also important to attain maximal benefit with immunotherapy. To provide guidance to the oncology community on these and other important concerns, the Society for Immunotherapy of Cancer (SITC) convened a multidisciplinary panel of experts to develop a clinical practice guideline (CPG). This CPG represents an update to SITC’s 2018 publication on immunotherapy for the treatment of NSCLC, and is expanded to include recommendations on SCLC and mesothelioma. The Expert Panel drew on the published literature as well as their clinical experience to develop recommendations for healthcare professionals on these important aspects of immunotherapeutic treatment for lung cancer and mesothelioma, including diagnostic testing, treatment planning, immune-related adverse events, and patient QOL considerations. The evidence- and consensus-based recommendations in this CPG are intended to give guidance to cancer care providers using immunotherapy to treat patients with lung cancer or mesothelioma.
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- 2022
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