1. Yearly changes in the composition of gut microbiota in the elderly, and the effect of lactobacilli intake on these changes
- Author
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Ryuta Amamoto, Kazuhito Shimamoto, Sungjin Park, Hoshitaka Matsumoto, Kensuke Shimizu, Miyuki Katto, Hirokazu Tsuji, Satoshi Matsubara, Roy J. Shephard, and Yukitoshi Aoyagi
- Subjects
Medicine ,Science - Abstract
Abstract The onset and worsening of some diseases are related to the variation and instability of gut microbiota. However, studies examining the personal variation of gut microbiota in detail are limited. Here, we evaluated the yearly variation of individual gut microbiota in 218 Japanese subjects aged 66–91 years, using Jensen-Shannon distance (JSD) metrics. Approximately 9% of the subjects showed a substantial change, as their formerly predominant bacterial families were replaced over the year. These subjects consumed fermented milk products less frequently than their peers. The relationship between the intake frequencies of fermented milk products containing Lactocaseibacillus paracasei strain Shirota (LcS) and JSD values was also investigated. The intra-individual JSD of subjects ingesting LcS products ≥ 3 days/week over the past 10 years was statistically lower than the
- Published
- 2021
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