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3. Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Author

Hemmes, Sabrine NT., Gama de Abreu, Marcelo, Severgnini, Paolo, Hollmann, Markus W., Binnekade, Jan M., Wrigge, Hermann, Canet, Jaume, Hiesmayr, Michael, Schmid, Werner, Tschernko, Edda, Jaber, Samir, Hedenstierna, Göran, Putensen, Christian, Pelosi, Paolo, Schultz, Marcus J., Marti, Agnes, Bacuzzi, Alessandro, Brodhun, Alexander, Molin, Alexandre, Merten, Alfred, Parera, Ana, Brunelli, Andrea, Cortegiani, Andrea, Güldner, Andreas, Reske, Andreas W., Gratarola, Angelo, Giarratano, Antonino, Bastin, Bea, Heyse, Bjorn, Mazul-Sunko, Branka, Amantea, Bruno, Barberis, Bruno, Uhlig, Christopher, Marín, Conrado Minguez, Celentano, Cristian, La Bella, Daniela, D’Antini, David, Velghe, David, Sulemanji, Demet, De Robertis, Edoardo, Hartmann, Eric, Montalto, Francesca, Tropea, Francesco, Mills, Gary H., Cinnella, Gilda, Della Rocca, Giorgio, Caggianelli, Girolamo, Pellerano, Giulia, Mollica, Giuseppina, Bugedo, Guillermo, Mulier, Jan-Paul, Vandenbrande, Jeroen, Geib, Johann, Yaqub, Jonathan, Florez, Jorge, Mayoral, Juan F., Sprung, Juraj, Van Limmen, Jurgen, Bos, Lieuwe DJ., de Baerdemaeker, Luc, Jamaer, Luc, Spagnolo, Luigi, Strys, Lydia, Gil, Manuel Granell, Vidal Melo, Marcos F., Unzueta, Maria Carmen, Moral, Maria Victoria, Ferner, Marion, Weiss, Martin, Vanoni, Massimo, Schaefer, Maximilian S., Prieto, Mercè, Grio, Michele, Spieth, Peter Markus, Simon, Philipp, Bodger, Phoebe, Sierra, Pilar, Laufenberg-Feldmann, Rita, Rusca, Roberta, Proietti, Rodolfo, Raineri, Santi Maurizio, Caroleo, Santo, Sabaté, Sergi, De Hert, Stefan, Pezzato, Stefano, Treschan, Tanja A., Goranovic, Tatjana, Koch, Thea, Bluth, Thomas, Kiss, Thomas, Perilli, Valter, Cegarra, Virginia, Ferrando, Carlos, Belda, Javier, Soro, Marina, Unzueta, Carmen, Suarez-Sipmann, Fernando, Librero, Julián, Llombart, Alicia, Rovira, Lucas, Granell, Manuel, Aldecoa, César, Diaz-Cambronero, Oscar, Balust, Jaume, Garutti, Ignacio, Gonzalez, Rafael, Gallego, Lucia, Garcia del Valle, Santiago, Redondo, Javier, Pestaña, David, Rodríguez, Aurelio, García, Javier, Matta, Manuel de la, Ibáñez, Maite, Barrios, Francisco, Hernández, Samuel, Torres, Vicente, Peiró, Salvador, Pozo, Natividad, Villena, Abigail, Carramiñana, Albert, Gallego-Casilda, Alberto, Duca, Alejandro, Alcón, Amalia, Miñana, Amanda, Asensio, Ana, Colás, Ana, Galve, Ana Isabel, Izquierdo, Ana, Jurado, Ana, Pérez, Ana María, Mugarra, Ana, Gutierrez, Andrea, De Miguel, Ángeles, Lozano, Angels, Katime, Antonio, Romero, Antonio, Garrigues, Beatriz, Ayas, Begoña, Arocas, Blanca, Delgado, Carlos, Fernández, Carmen, Romero, Carolina, Gallego, Clara, Garcés, Cristina, Lisbona, Cristina, Parrilla, Cristina, López-Herrera, Daniel, González, Domingo, Llamazares, Eduardo, Del Rio, Elena, Lozano, Elena, Pastor, Ernesto, Chamorro, Estefanía, Gracia, Estefanía, Sánchez, Ester, Romero, Esther, Díez, Fernando, Serralta, Ferran, Daviu, Francisco, Sandín, Francisco, Aguilar, Gerardo, Tusman, Gerardo, Azparren, Gonzalo, Martínez-Pallí, Graciela, Mazzinari, Guido, Benítez, Inmaculada, Hernandéz, Inmaculada, India, Inmaculada, León, Irene, Fuentes, Isabel, Ruiz, Isabel, Puig, Jaume, Román, Javie Ignacio, Acosta, Jesús, Rico-Feijoo, Jesús, Olmedo, Jonathan, Carbonell, Jose A., Alonso, Jose M., Pérez, Jose María, Marcos, Jose Miguel, Navarro, Jose, Valdivia, Jose, Carrizo, Juan, Piqueras, Laura, Soriano, Laura, Vaquero, Laura, Miguel, Lisset, Muñoz, Lorena, Valencia, Lucia, Olmedilla, Luis, Etulain, Mᵃ Justina, Tisner, Manuel, Barrio, María, Alonso, María Dolores, García, María, Hernández, María J., Alberola, María José, Parra, María, Argente, María Pilar, Vila, María, De Fez, Mario, Agilaga, Marta, Gine, Marta, Ayuso, Mercedes, García, Mercedes, Bejarano, Natalia, Peña, Natalia, Ojeda, Nazario, Martínez, Nilda, García, Nuria, Padrón, Oto, García, Pablo, Valls, Paola, Cruz, Patricia, Piñeiro, Patricia, Charco, Pedro, Anaya, Rafael, López, Ramiro, Rodríguez, Rayco, Martínez, Rocío, Pujol, Roger, Dosdá, Rosa, Lardies, Rosa, Díaz, Ruben, Villazala, Rubén, Zapatero, Sara, Cabrera, Sergio, Sánchez, Sergio, Martin, Silvia, Diaz, Suzana, Franco, Tania, Moreno, Tania, Socorro, Tania, Gilabert, Vicente, Balandrón, Victor, Moral, Victoria, Cegarra, Virgina, Varón, Viviana, Abelha, Fernando, Abitağaoğlu, Sühayla, Achilles, Marc, Adebesin, Afeez, Adriaensens, Ine, Ahene, Charles, Akbar, Fatima, Al Harbi, Mohammed, Al Khoury al Kallab, Rita, Albanel, Xavier, Aldenkortt, Florence, Saleh Alfouzan, Rawan Abdullah, Alruqaie, Reef, Altermatt, Fernando, Luís de Castro Araujo, Bruno, Arbesú, Genaro, Artsi, Hanna, Aurilio, Caterina, Ayanoglu, Omer Hilmi, Baig, Harris, Baird, Yolanda, Balonov, Konstantin, Banks, Samantha, Bao, Xiaodong, Baumgartner, Mélanie, Tortosa, Isabel Belda, Bergamaschi, Alice, Bergmann, Lars, Bigatello, Luca, Pérez, Elena Biosca, Birr, Katja, Bojaxhi, Elird, Bonenti, Chiara, Bonney, Iwona, Bos, Elke M.E., Bowman, Sara, Braz, Leandro Gobbo, Brugnoni, Elisa, Brull, Sorin J., Brunetti, Iole, Bruni, Andrea, Buenvenida, Shonie L., Busch, Cornelius Johannes, Camerini, Giovanni, Capatti, Beatrice, Carmona, Javiera, Carungcong, Jaime, Carvalho, Marta, Cattan, Anat, Cavaleiro, Carla, Chiumello, Davide, Ciardo, Stefano, Coburn, Mark, Colella, Umberto, Contreras, Victor, Dincer, Pelin Corman, Cotter, Elizabeth, Crovetto, Marcia, Darrah, William, Davies, Simon, Del Cojo Peces, Enrique, Delphin, Ellise, Diaper, John, Junior, Paulo do Nascimento, Donatiello, Valerio, Dong, Jing, Dourado, Maria do Socorro, Dullenkopf, Alexander, Ebner, Felix, Elgendy, Hamed, Ellenberger, Christoph, Arı, Dilek Erdoğan, Ermert, Thomas, Farah, Fadi, Fernandez-Bustamante, Ana, Ferreira, Cristina, Fiore, Marco, Fonte, Ana, Palahí, Christina Fortià, Galimberti, Andrea, Garofano, Najia, Giaccari, Luca Gregorio, Gilsanz, Fernando, Girrbach, Felix, Gobbi, Luca, Godfried, Marc Bernard, Goettel, Nicolai, Goldstein, Peter A., Goren, Or, Gorlin, Andrew, Graterol, Juan, Guyon, Pierre, Haire, Kevin, Harou, Philippe, Helf, Antonia, Hemmes, Sabrine N.T., Hempel, Gunther, Hernández Cádiz, María José, Heyse, Björn, Huercio, Ivan, Ilievska, Jasmina, Jakus, Lien, Jeganath, Vijay, Jelting, Yvonne, Jung, Minoa, Kabon, Barbara, Kacha, Aalok, Ilić, Maja Karaman, Karuppiah, Arunthevaraja, Kavas, Ayse Duygu, Barcelos, Gleicy Keli, Kellogg, Todd A., Kemper, Johann, Kerbrat, Romain, Khodr, Suraya, Kienbaum, Peter, Kir, Bunyamin, Kivrak, Selin, Klarić, Vlasta, Köksal, Ceren, Kowark, Ana, Kranke, Peter, Kuvaki, Bahar, Kuzmanovska, Biljana, Laffey, John, Lange, Mirko, Freitas de Lemos, Marília, Licker, Marc-Joseph, López-Baamonde, Manuel, López-Hernández, Antonio, Lopez-Martinez, Mercedes, Luise, Stéphane, MacGregor, Mark, Magalhães, Danielle, Maillard, Julien, Malerbi, Patrizia, Manimekalai, Natesan, Margarson, Michael, Markstaller, Klaus, Martin, Archer K., Martin, David P., Martin, Yvette N., Martínez-Ocon, Julia, Martin-Loeches, Ignacio, Maseda, Emilio, Matot, Idit, McAuliffe, Niamh, McKenzie, Travis J., Medina, Paulina, Meersch, Melanie, Menzen, Angelika, Mertens, Els, Meurer, Bernd, Meyer-Treschan, Tanja, Miao, Changhong, Micalizzi, Camilla, Milić, Morena, Pinheiro Módolo, Norma Sueli, Moine, Pierre, Mölders, Patrick, Montero-Feijoo, Ana, Moret, Enrique, Muller, Markus K., Murphy, Zoe, Nalwaya, Pramod, Naumovski, Filip, Navalesi, Paolo, Navarro e Lima, Lais Helena, Adam, Višnja Nesek, Neumann, Claudia, Newell, Christopher, Nisnevitch, Zoulfira, Nizamuddin, Junaid, Novazzi, Cecilia, O'Connor, Michael, Oprea, Günther, Sungur, Mukadder Orhan, Özbilgin, Şule, Pace, Maria Caterina, Pacheco, Marcos, Packianathaswamy, Balaji, Gonzalez, Estefania Palma, Papaspyros, Fotios, Paredes, Sebastián, Passavanti, Maria Beatrice, Pedemonte, Juan Cristobal, Peremin, Sanja, Philipsenburg, Christoph, Pinho, Daniela, Pinho, Silvia, Posthuma, Linda M., Pota, Vincenzo, Preckel, Benedikt, Priani, Paolo, Rached, Mohamed Aymen, Radoeshki, Aleksandar, Ragazzi, Riccardo, Rajamanickam, Tamilselvan, Rajamohan, Arthi, Ramakrishna, Harish, Rangarajan, Desikan, Reiterer, Christian, Renew, J. Ross, Reynaud, Thomas, Rhys, Rhidian, Rivas, Eva, Robitzky, Luisa, Rossaint, Rolf, Rubulotta, Francesca, Machado, Humberto S., Nunes, Catarina S., Sabbatini, Giovanni, Samuels, Jon D., Sanahuja, Josep Martí, Sansone, Pasquale, Santos, Alice, Sayedalahl, Mohamed, Scharffenberg, Martin, Schiffer, Eduardo, Schliewe, Nadja, Schorer, Raoul, Schumann, Roman, Selmo, Gabriele, Sendra, Mar, Senturk, Mert, Shaw, Kate, Shosholcheva, Mirjana, Sibai, Abdulrazak, Simonassi, Francesca, Sinno, Claudia, Sivrikoz, Nukhet, Skandalou, Vasiliki, Smith, Neil, Soares, Maria, Artiles, Tania Socorro, Castro, Diogo Sousa, Sousa, Miguel, Spadaro, Savino, Stamatakis, Emmanouil, Steiner, Luzius A., Stevenazzi, Andrea, Suarez-de-la-Rica, Alejandro, Suppan, Mélanie, Teichmann, Robert, Tena Guerrero, José Maria, Thiel, Bram, Tolós, Raquel, Altun, Gulbin Tore, Tucci, Michelle, Turnbull, Zachary A., Turudić, Žana, Unterberg, Matthias, Van Nieuwenhove, Yves, Van Waesberghe, Julia, Vidal Melo, Marcos Francisco, Vitković, Bibiana, Vivona, Luigi, Vizcaychipi, Marcela, Volta, Carlo Alberto, Weber, Anne, Weingarten, Toby N., Wittenstein, Jakob, Wyffels, Piet, Yagüe, Julio, Yates, David, Yavru, Ayşen, Zac, Lilach, Zhong, Jing, Campos, Niklas S., Librero, Julian, Ball, Lorenzo, and Serpa Neto, A.

Published
2022
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5. Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy: a randomised controlled trial

Author

Acosta, Jesús, Alberola, María J., Alcón, Amalia, Almajano, Rosa, Álvarez, Carlos, Anaya, Rafael, Aragón, Cristian, Argilaga, Marta, Arocas, Blanca, Ayas, Begoña, Balandrón, Victor, Bárcena, Elizabeth, Bejarano, Natalia, Belmonte, Luis, Berges, Vanesa, Guillén Bermejo, Maria, Cabadas, Rafael, Cabrera, Sergio, Callejas, Raquel, Carbonell, Jose, Carrizo, Juan, Castillo, Jesús, Charco, Pedro, Colás, Ana, Colomina, Lorena, Cotter, Laura, Cruz, Patricia, Cuervo, Javier, Del Castillo, Gema, Del Río, Elena, Delgado, Juan, Dexeus, Carlos, Díaz, Rubén, Dinu, Mandalina, Duca, Alejandro, Duque, Paula, Echarri, Gemma, Fabra, Patricia, Fernández, Carmen, Florea, Raluca, Forcada, Pilar, Fuentes, Isabel, Garcés, Cristina, Del Valle, Santiago G., García, Beatriz, García, Esther, García, María, García, Mercedes, Garrigues, Beatriz, Garutti, Ignacio, Gil, Fernando, González, Domingo, Gracia, Alejandro, Gracia, Estefanía, Granell, Manuel, Guerra, Yessica, Gutierrez, Andrea, Hernando, Julia, Herrero, Miriam, Ibáñez, Maite, Imaz, Inés, Izquierdo, Blanca, Jurado, Ana, Lafuente, Noelia, Lascorz, Laura, León, Irene, López, Antonio, López-Herrera, Daniel, Lozano, Angels, Marcos, José M., Martínez, Graciela, Martínez, Sara, Mata, Esperanza, Matoses, Salomé, Mendez, Rosa, Merino, María, Millaruelo, Andrés, Molina, Carlos R., Monleon, Berta, Montenegro, Omar M., Mugarra, Ana, Muñoz, Jose L., Oliver-Forniés, Pablo, Ortega, Manuel, Palencia, María A., Parera, Ana, Pastor, Ernesto, del Mar Pérez, Maria, Pérez, Sara, Pestaña, David, Piñol, Santiago, Puig, Jaume, Pujol, Roger, Quesada, Natividad, Ramón, Ana, Rego, Consuelo, Reviriego, Laura, Rodríguez, Rayco, Romero, Blanca, Romero, Esther, Roselló, Marta, Rovira, Lucas, Ruiz, Lola, Sancho, Laura, Sandín, Francisco, Serralta, Ferran, Tres, Eva, Valls, Paola, Vaquero, Laura, Varela, Marina, Vega, Victor, Viguera, Laura, Villazala, Rubén, Villena, Abigail, Visiedo, Sara, Ferrando, Carlos, Aldecoa, César, Unzueta, Carmen, Belda, F. Javier, Librero, Julián, Tusman, Gerardo, Suárez-Sipmann, Fernando, Peiró, Salvador, Pozo, Natividad, Brunelli, Andrea, Gallego, Clara, Rodríguez, Aurelio, García, Jose Ignacio, Díaz-Cambronero, Oscar, Balust, Jaume, Redondo, Francisco J., de la Matta, Manuel, Gallego-Ligorit, Lucía, Hernández, Javier, Martínez, Pascual, Pérez, Ana, Leal, Sonsoles, Alday, Enrique, Monedero, Pablo, González, Rafael, Mazzirani, Guido, Aguilar, Gerardo, López-Baamonde, Manuel, Felipe, Mar, Torrente, Jara, Valencia, Lucia, Varón, Viviana, Sánchez, Sergio, Rodríguez, Benigno, Martín, Ana, India, Inmaculada, Azparren, Gonzalo, Molina, Rodrigo, Villar, Jesús, and Soro, Marina

Published
2020
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6. Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE): a randomised controlled trial

Author

Acosta, Jesús, Aguilar, Gerardo, Alberola, María José, Alcón, Amalia, Alonso, Jose M., Alonso, María Dolores, Anaya, Rafael, Argente, María Pilar, Agilaga, Marta, Arocas, Blanca, Asensio, Ana, Ayas, Begoña, Ayuso, Mercedes, Balandrón, Victor, Barrio, María, Bejarano, Natalia, Benítez, Inmaculada, Cabrera, Sergio, Carbonell, Jose A., Carramiñana, Albert, Carrizo, Juan, Cegarra, Virginia, Chamorro, Estefanía, Charco, Pedro, Cruz, Patricia, Daviu, Francisco, De Fez, Mario, De Miguel, Ángeles, Del Río, Elena, Delgado, Carlos, Díaz, Ruben, Díaz, Susana, Díez, Fernando, Dosdá, Rosa, Duca, Alejandro, Etulain, M<ce:sup loc='post">a</ce:sup> Justina, Fernández, Carmen, Franco, Tania, Fuentes, Isabel, Gallego, Clara, Gallego-Casilda, Alberto, Galve, Ana Isabel, Garcés, Cristina, García, Mercedes, García, Pablo, Garrigues, Beatriz, Gilabert, Vicente, González, Domingo, Gutiérrez, Andrea, Hernández, Inmaculada, Izquierdo, Ana, Jurado, Ana, Katime, Antonio, Llamazares, Eduardo, Lardies, Rosa, Lisbona, Cristina, López-Herrera, Daniel, López, Ramiro, Lozano, Angels, Lozano, Elena, Marcos, Jose Miguel, Martin, Silvia, Martínez, Nilda, Martínez, Rocío, Martínez-Pallí, Graciella, Mazzinari, Guido, Miñana, Amanda, Moral, Victoria, Moreno, Tania, Mugarra, Ana, Muñoz, Lorena, Navarro, Jose, Olmedilla, Luis, Olmedo, Jonathan, Ojeda, Nazario, Parera, Ana, Parra, María, Parrilla, Cristina, Pastor, Ernesto, Peña, Natalia, Pérez, Ana María, Pérez, Jose María, Piqueras, Laura, Rico-Feijoo, Jesús, Rodríguez, Rayco, Román, Javier Ignacio, Romero, Antonio, Romero, Carolina, Romero, Esther, Ruiz, Isabel, Sánchez, Ester, Sandín, Francisco, Serralta, Ferran, Socorro, Tania, Soriano, Laura, Tisner, Manuel, Valencia, Lucia, Valls, Paola, Vaquero, Laura, Varón, Viviana, Vila, María, Villazala, Rubén, Villena, Abigail, Zapatero, Sara, Ferrando, Carlos, Soro, Marina, Unzueta, Carmen, Suarez-Sipmann, Fernando, Canet, Jaume, Librero, Julián, Pozo, Natividad, Peiró, Salvador, Llombart, Alicia, León, Irene, India, Inmaculada, Aldecoa, Cesar, Díaz-Cambronero, Oscar, Pestaña, David, Redondo, Francisco J, Garutti, Ignacio, Balust, Jaume, García, Jose I, Ibáñez, Maite, Granell, Manuel, Rodríguez, Aurelio, Gallego, Lucía, de la Matta, Manuel, Gonzalez, Rafael, Brunelli, Andrea, García, Javier, Rovira, Lucas, Barrios, Francisco, Torres, Vicente, Hernández, Samuel, Gracia, Estefanía, Giné, Marta, García, María, García, Nuria, Miguel, Lisset, Sánchez, Sergio, Piñeiro, Patricia, Pujol, Roger, García-del-Valle, Santiago, Valdivia, José, Hernández, María J, Padrón, Oto, Colás, Ana, Puig, Jaume, Azparren, Gonzalo, Tusman, Gerardo, Villar, Jesús, and Belda, Javier

Published
2018
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11. Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Author

Campos, Niklas S., primary, Bluth, Thomas, additional, Hemmes, Sabrine N.T., additional, Librero, Julian, additional, Pozo, Natividad, additional, Ferrando, Carlos, additional, Ball, Lorenzo, additional, Mazzinari, Guido, additional, Pelosi, Paolo, additional, Gama de Abreu, Marcelo, additional, Schultz, Marcus J., additional, Serpa Neto, A., additional, Hemmes, Sabrine NT., additional, Severgnini, Paolo, additional, Hollmann, Markus W., additional, Binnekade, Jan M., additional, Wrigge, Hermann, additional, Canet, Jaume, additional, Hiesmayr, Michael, additional, Schmid, Werner, additional, Tschernko, Edda, additional, Jaber, Samir, additional, Hedenstierna, Göran, additional, Putensen, Christian, additional, Marti, Agnes, additional, Bacuzzi, Alessandro, additional, Brodhun, Alexander, additional, Molin, Alexandre, additional, Merten, Alfred, additional, Parera, Ana, additional, Brunelli, Andrea, additional, Cortegiani, Andrea, additional, Güldner, Andreas, additional, Reske, Andreas W., additional, Gratarola, Angelo, additional, Giarratano, Antonino, additional, Bastin, Bea, additional, Heyse, Bjorn, additional, Mazul-Sunko, Branka, additional, Amantea, Bruno, additional, Barberis, Bruno, additional, Uhlig, Christopher, additional, Marín, Conrado Minguez, additional, Celentano, Cristian, additional, La Bella, Daniela, additional, D’Antini, David, additional, Velghe, David, additional, Sulemanji, Demet, additional, De Robertis, Edoardo, additional, Hartmann, Eric, additional, Montalto, Francesca, additional, Tropea, Francesco, additional, Mills, Gary H., additional, Cinnella, Gilda, additional, Della Rocca, Giorgio, additional, Caggianelli, Girolamo, additional, Pellerano, Giulia, additional, Mollica, Giuseppina, additional, Bugedo, Guillermo, additional, Mulier, Jan-Paul, additional, Vandenbrande, Jeroen, additional, Geib, Johann, additional, Yaqub, Jonathan, additional, Florez, Jorge, additional, Mayoral, Juan F., additional, Sprung, Juraj, additional, Van Limmen, Jurgen, additional, Bos, Lieuwe DJ., additional, de Baerdemaeker, Luc, additional, Jamaer, Luc, additional, Spagnolo, Luigi, additional, Strys, Lydia, additional, Gil, Manuel Granell, additional, Vidal Melo, Marcos F., additional, Unzueta, Maria Carmen, additional, Moral, Maria Victoria, additional, Ferner, Marion, additional, Weiss, Martin, additional, Vanoni, Massimo, additional, Schaefer, Maximilian S., additional, Prieto, Mercè, additional, Grio, Michele, additional, Spieth, Peter Markus, additional, Simon, Philipp, additional, Bodger, Phoebe, additional, Sierra, Pilar, additional, Laufenberg-Feldmann, Rita, additional, Rusca, Roberta, additional, Proietti, Rodolfo, additional, Raineri, Santi Maurizio, additional, Caroleo, Santo, additional, Sabaté, Sergi, additional, De Hert, Stefan, additional, Pezzato, Stefano, additional, Treschan, Tanja A., additional, Goranovic, Tatjana, additional, Koch, Thea, additional, Kiss, Thomas, additional, Perilli, Valter, additional, Cegarra, Virginia, additional, Belda, Javier, additional, Soro, Marina, additional, Unzueta, Carmen, additional, Suarez-Sipmann, Fernando, additional, Librero, Julián, additional, Llombart, Alicia, additional, Rovira, Lucas, additional, Granell, Manuel, additional, Aldecoa, César, additional, Diaz-Cambronero, Oscar, additional, Balust, Jaume, additional, Garutti, Ignacio, additional, Gonzalez, Rafael, additional, Gallego, Lucia, additional, Garcia del Valle, Santiago, additional, Redondo, Javier, additional, Pestaña, David, additional, Rodríguez, Aurelio, additional, García, Javier, additional, Matta, Manuel de la, additional, Ibáñez, Maite, additional, Barrios, Francisco, additional, Hernández, Samuel, additional, Torres, Vicente, additional, Peiró, Salvador, additional, Villena, Abigail, additional, Carramiñana, Albert, additional, Gallego-Casilda, Alberto, additional, Duca, Alejandro, additional, Alcón, Amalia, additional, Miñana, Amanda, additional, Asensio, Ana, additional, Colás, Ana, additional, Galve, Ana Isabel, additional, Izquierdo, Ana, additional, Jurado, Ana, additional, Pérez, Ana María, additional, Mugarra, Ana, additional, Gutierrez, Andrea, additional, De Miguel, Ángeles, additional, Lozano, Angels, additional, Katime, Antonio, additional, Romero, Antonio, additional, Garrigues, Beatriz, additional, Ayas, Begoña, additional, Arocas, Blanca, additional, Delgado, Carlos, additional, Fernández, Carmen, additional, Romero, Carolina, additional, Gallego, Clara, additional, Garcés, Cristina, additional, Lisbona, Cristina, additional, Parrilla, Cristina, additional, López-Herrera, Daniel, additional, González, Domingo, additional, Llamazares, Eduardo, additional, Del Rio, Elena, additional, Lozano, Elena, additional, Pastor, Ernesto, additional, Chamorro, Estefanía, additional, Gracia, Estefanía, additional, Sánchez, Ester, additional, Romero, Esther, additional, Díez, Fernando, additional, Serralta, Ferran, additional, Daviu, Francisco, additional, Sandín, Francisco, additional, Aguilar, Gerardo, additional, Tusman, Gerardo, additional, Azparren, Gonzalo, additional, Martínez-Pallí, Graciela, additional, Benítez, Inmaculada, additional, Hernandéz, Inmaculada, additional, India, Inmaculada, additional, León, Irene, additional, Fuentes, Isabel, additional, Ruiz, Isabel, additional, Puig, Jaume, additional, Román, Javie Ignacio, additional, Acosta, Jesús, additional, Rico-Feijoo, Jesús, additional, Olmedo, Jonathan, additional, Carbonell, Jose A., additional, Alonso, Jose M., additional, Pérez, Jose María, additional, Marcos, Jose Miguel, additional, Navarro, Jose, additional, Valdivia, Jose, additional, Carrizo, Juan, additional, Piqueras, Laura, additional, Soriano, Laura, additional, Vaquero, Laura, additional, Miguel, Lisset, additional, Muñoz, Lorena, additional, Valencia, Lucia, additional, Olmedilla, Luis, additional, Etulain, Mᵃ Justina, additional, Tisner, Manuel, additional, Barrio, María, additional, Alonso, María Dolores, additional, García, María, additional, Hernández, María J., additional, Alberola, María José, additional, Parra, María, additional, Argente, María Pilar, additional, Vila, María, additional, De Fez, Mario, additional, Agilaga, Marta, additional, Gine, Marta, additional, Ayuso, Mercedes, additional, García, Mercedes, additional, Bejarano, Natalia, additional, Peña, Natalia, additional, Ojeda, Nazario, additional, Martínez, Nilda, additional, García, Nuria, additional, Padrón, Oto, additional, García, Pablo, additional, Valls, Paola, additional, Cruz, Patricia, additional, Piñeiro, Patricia, additional, Charco, Pedro, additional, Anaya, Rafael, additional, López, Ramiro, additional, Rodríguez, Rayco, additional, Martínez, Rocío, additional, Pujol, Roger, additional, Dosdá, Rosa, additional, Lardies, Rosa, additional, Díaz, Ruben, additional, Villazala, Rubén, additional, Zapatero, Sara, additional, Cabrera, Sergio, additional, Sánchez, Sergio, additional, Martin, Silvia, additional, Diaz, Suzana, additional, Franco, Tania, additional, Moreno, Tania, additional, Socorro, Tania, additional, Gilabert, Vicente, additional, Balandrón, Victor, additional, Moral, Victoria, additional, Cegarra, Virgina, additional, Varón, Viviana, additional, Abelha, Fernando, additional, Abitağaoğlu, Sühayla, additional, Achilles, Marc, additional, Adebesin, Afeez, additional, Adriaensens, Ine, additional, Ahene, Charles, additional, Akbar, Fatima, additional, Al Harbi, Mohammed, additional, Al Khoury al Kallab, Rita, additional, Albanel, Xavier, additional, Aldenkortt, Florence, additional, Saleh Alfouzan, Rawan Abdullah, additional, Alruqaie, Reef, additional, Altermatt, Fernando, additional, Luís de Castro Araujo, Bruno, additional, Arbesú, Genaro, additional, Artsi, Hanna, additional, Aurilio, Caterina, additional, Ayanoglu, Omer Hilmi, additional, Baig, Harris, additional, Baird, Yolanda, additional, Balonov, Konstantin, additional, Banks, Samantha, additional, Bao, Xiaodong, additional, Baumgartner, Mélanie, additional, Tortosa, Isabel Belda, additional, Bergamaschi, Alice, additional, Bergmann, Lars, additional, Bigatello, Luca, additional, Pérez, Elena Biosca, additional, Birr, Katja, additional, Bojaxhi, Elird, additional, Bonenti, Chiara, additional, Bonney, Iwona, additional, Bos, Elke M.E., additional, Bowman, Sara, additional, Braz, Leandro Gobbo, additional, Brugnoni, Elisa, additional, Brull, Sorin J., additional, Brunetti, Iole, additional, Bruni, Andrea, additional, Buenvenida, Shonie L., additional, Busch, Cornelius Johannes, additional, Camerini, Giovanni, additional, Capatti, Beatrice, additional, Carmona, Javiera, additional, Carungcong, Jaime, additional, Carvalho, Marta, additional, Cattan, Anat, additional, Cavaleiro, Carla, additional, Chiumello, Davide, additional, Ciardo, Stefano, additional, Coburn, Mark, additional, Colella, Umberto, additional, Contreras, Victor, additional, Dincer, Pelin Corman, additional, Cotter, Elizabeth, additional, Crovetto, Marcia, additional, Darrah, William, additional, Davies, Simon, additional, Del Cojo Peces, Enrique, additional, Delphin, Ellise, additional, Diaper, John, additional, Junior, Paulo do Nascimento, additional, Donatiello, Valerio, additional, Dong, Jing, additional, Dourado, Maria do Socorro, additional, Dullenkopf, Alexander, additional, Ebner, Felix, additional, Elgendy, Hamed, additional, Ellenberger, Christoph, additional, Arı, Dilek Erdoğan, additional, Ermert, Thomas, additional, Farah, Fadi, additional, Fernandez-Bustamante, Ana, additional, Ferreira, Cristina, additional, Fiore, Marco, additional, Fonte, Ana, additional, Palahí, Christina Fortià, additional, Galimberti, Andrea, additional, Garofano, Najia, additional, Giaccari, Luca Gregorio, additional, Gilsanz, Fernando, additional, Girrbach, Felix, additional, Gobbi, Luca, additional, Godfried, Marc Bernard, additional, Goettel, Nicolai, additional, Goldstein, Peter A., additional, Goren, Or, additional, Gorlin, Andrew, additional, Graterol, Juan, additional, Guyon, Pierre, additional, Haire, Kevin, additional, Harou, Philippe, additional, Helf, Antonia, additional, Hempel, Gunther, additional, Hernández Cádiz, María José, additional, Heyse, Björn, additional, Huercio, Ivan, additional, Ilievska, Jasmina, additional, Jakus, Lien, additional, Jeganath, Vijay, additional, Jelting, Yvonne, additional, Jung, Minoa, additional, Kabon, Barbara, additional, Kacha, Aalok, additional, Ilić, Maja Karaman, additional, Karuppiah, Arunthevaraja, additional, Kavas, Ayse Duygu, additional, Barcelos, Gleicy Keli, additional, Kellogg, Todd A., additional, Kemper, Johann, additional, Kerbrat, Romain, additional, Khodr, Suraya, additional, Kienbaum, Peter, additional, Kir, Bunyamin, additional, Kivrak, Selin, additional, Klarić, Vlasta, additional, Köksal, Ceren, additional, Kowark, Ana, additional, Kranke, Peter, additional, Kuvaki, Bahar, additional, Kuzmanovska, Biljana, additional, Laffey, John, additional, Lange, Mirko, additional, Freitas de Lemos, Marília, additional, Licker, Marc-Joseph, additional, López-Baamonde, Manuel, additional, López-Hernández, Antonio, additional, Lopez-Martinez, Mercedes, additional, Luise, Stéphane, additional, MacGregor, Mark, additional, Magalhães, Danielle, additional, Maillard, Julien, additional, Malerbi, Patrizia, additional, Manimekalai, Natesan, additional, Margarson, Michael, additional, Markstaller, Klaus, additional, Martin, Archer K., additional, Martin, David P., additional, Martin, Yvette N., additional, Martínez-Ocon, Julia, additional, Martin-Loeches, Ignacio, additional, Maseda, Emilio, additional, Matot, Idit, additional, McAuliffe, Niamh, additional, McKenzie, Travis J., additional, Medina, Paulina, additional, Meersch, Melanie, additional, Menzen, Angelika, additional, Mertens, Els, additional, Meurer, Bernd, additional, Meyer-Treschan, Tanja, additional, Miao, Changhong, additional, Micalizzi, Camilla, additional, Milić, Morena, additional, Pinheiro Módolo, Norma Sueli, additional, Moine, Pierre, additional, Mölders, Patrick, additional, Montero-Feijoo, Ana, additional, Moret, Enrique, additional, Muller, Markus K., additional, Murphy, Zoe, additional, Nalwaya, Pramod, additional, Naumovski, Filip, additional, Navalesi, Paolo, additional, Navarro e Lima, Lais Helena, additional, Adam, Višnja Nesek, additional, Neumann, Claudia, additional, Newell, Christopher, additional, Nisnevitch, Zoulfira, additional, Nizamuddin, Junaid, additional, Novazzi, Cecilia, additional, O'Connor, Michael, additional, Oprea, Günther, additional, Sungur, Mukadder Orhan, additional, Özbilgin, Şule, additional, Pace, Maria Caterina, additional, Pacheco, Marcos, additional, Packianathaswamy, Balaji, additional, Gonzalez, Estefania Palma, additional, Papaspyros, Fotios, additional, Paredes, Sebastián, additional, Passavanti, Maria Beatrice, additional, Pedemonte, Juan Cristobal, additional, Peremin, Sanja, additional, Philipsenburg, Christoph, additional, Pinho, Daniela, additional, Pinho, Silvia, additional, Posthuma, Linda M., additional, Pota, Vincenzo, additional, Preckel, Benedikt, additional, Priani, Paolo, additional, Rached, Mohamed Aymen, additional, Radoeshki, Aleksandar, additional, Ragazzi, Riccardo, additional, Rajamanickam, Tamilselvan, additional, Rajamohan, Arthi, additional, Ramakrishna, Harish, additional, Rangarajan, Desikan, additional, Reiterer, Christian, additional, Renew, J. Ross, additional, Reynaud, Thomas, additional, Rhys, Rhidian, additional, Rivas, Eva, additional, Robitzky, Luisa, additional, Rossaint, Rolf, additional, Rubulotta, Francesca, additional, Machado, Humberto S., additional, Nunes, Catarina S., additional, Sabbatini, Giovanni, additional, Samuels, Jon D., additional, Sanahuja, Josep Martí, additional, Sansone, Pasquale, additional, Santos, Alice, additional, Sayedalahl, Mohamed, additional, Scharffenberg, Martin, additional, Schiffer, Eduardo, additional, Schliewe, Nadja, additional, Schorer, Raoul, additional, Schumann, Roman, additional, Selmo, Gabriele, additional, Sendra, Mar, additional, Senturk, Mert, additional, Shaw, Kate, additional, Shosholcheva, Mirjana, additional, Sibai, Abdulrazak, additional, Simonassi, Francesca, additional, Sinno, Claudia, additional, Sivrikoz, Nukhet, additional, Skandalou, Vasiliki, additional, Smith, Neil, additional, Soares, Maria, additional, Artiles, Tania Socorro, additional, Castro, Diogo Sousa, additional, Sousa, Miguel, additional, Spadaro, Savino, additional, Stamatakis, Emmanouil, additional, Steiner, Luzius A., additional, Stevenazzi, Andrea, additional, Suarez-de-la-Rica, Alejandro, additional, Suppan, Mélanie, additional, Teichmann, Robert, additional, Tena Guerrero, José Maria, additional, Thiel, Bram, additional, Tolós, Raquel, additional, Altun, Gulbin Tore, additional, Tucci, Michelle, additional, Turnbull, Zachary A., additional, Turudić, Žana, additional, Unterberg, Matthias, additional, Van Nieuwenhove, Yves, additional, Van Waesberghe, Julia, additional, Vidal Melo, Marcos Francisco, additional, Vitković, Bibiana, additional, Vivona, Luigi, additional, Vizcaychipi, Marcela, additional, Volta, Carlo Alberto, additional, Weber, Anne, additional, Weingarten, Toby N., additional, Wittenstein, Jakob, additional, Wyffels, Piet, additional, Yagüe, Julio, additional, Yates, David, additional, Yavru, Ayşen, additional, Zac, Lilach, additional, and Zhong, Jing, additional

Published
2022
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13. An Individualized Low-Pneumoperitoneum-Pressure Strategy May Prevent a Reduction in Liver Perfusion during Colorectal Laparoscopic Surgery.

Author

Olmedilla Arnal, Luis Enrique, Cambronero, Oscar Diaz, Mazzinari, Guido, Pérez Peña, José María, Zorrilla Ortúzar, Jaime, Rodríguez Martín, Marcos, Vila Montañes, Maria, Schultz, Marcus J., Rovira, Lucas, and Argente Navarro, Maria Pilar

Subjects
LAPAROSCOPIC surgery, PROCTOLOGY, PERFUSION, LIVER surgery, LIVER, INTRA-abdominal pressure
Abstract

High intra-abdominal pressure (IAP) during laparoscopic surgery is associated with reduced splanchnic blood flow. It is uncertain whether a low IAP prevents this reduction. We assessed the effect of an individualized low-pneumoperitoneum-pressure strategy on liver perfusion. This was a single-center substudy of the multicenter 'Individualized Pneumoperitoneum Pressure in Colorectal Laparoscopic Surgery versus Standard Therapy II study' (IPPCollapse–II), a randomized clinical trial in which patients received an individualized low-pneumoperitoneum strategy (IPP) or a standard pneumoperitoneum strategy (SPP). Liver perfusion was indirectly assessed by the indocyanine green plasma disappearance rate (ICG–PDR) and the secondary endpoint was ICG retention rate after 15 min (R15) using pulse spectrophotometry. Multivariable beta regression was used to assess the association between group assignment and ICG–PDR and ICG–R15. All 29 patients from the participating center were included. Median IAP was 8 (25th–75th percentile: 8–10) versus 12 (12,12) mmHg, in IPP and SPP patients, respectively (p < 0.001). ICG–PDR was higher (OR 1.42, 95%-CI 1.10–1.82; p = 0.006) and PDR–R15 was lower in IPP patients compared with SPP patients (OR 0.46, 95%-CI 0.29–0.73; p = 0.001). During laparoscopic colorectal surgery, an individualized low pneumoperitoneum may prevent a reduction in liver perfusion. [ABSTRACT FROM AUTHOR]

Published
2023
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15. Modeling intra-abdominal volume and respiratory driving pressure during pneumoperitoneum insufflation—a patient-level data meta-analysis

Author

Mazzinari, Guido, primary, Diaz-Cambronero, Oscar, additional, Serpa Neto, Ary, additional, Martínez, Antonio Cañada, additional, Rovira, Lucas, additional, Argente Navarro, María Pilar, additional, Malbrain, Manu L.N.G, additional, Pelosi, Paolo, additional, Gama de Abreu, Marcelo, additional, Hollmann, Markus W., additional, and Schultz, Marcus J., additional

Published
2021
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16. Modeling intra-abdominal volume and respiratory driving pressure during pneumoperitoneum insufflation - a patient-level data meta-analysis

Author

Mazzinari, Guido, Diaz-Cambronero, Oscar, Serpa Neto, Ary, Canada Martinez, Antonio, Rovira, Lucas, Argente Navarro, Maria Pilar, Malbrain, Manu L N G, Pelosi, Paolo, Gama de Abreu, Marcelo, Hollmann, Markus W, Schultz, Marcus J, and Study Investigators, IPPCoILapSE

Subjects
body regions, Laparoscopy, abdominal volume, abdominal pressure, perioperative medicine, abdominal compliance
Abstract

During pneumoperitoneum, intra-abdominal pressure (IAP) is usually kept at 12-14 mmHg. There is no clinical benefit in IAP increments if they do not increase intra-abdominal volume IAV. We aimed to estimate IAV (?IAV) and respiratory driving pressure chan

Published
2020

17. Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy : a randomised controlled trial

Author

Ferrando, Carlos, Aldecoa, Cesar, Unzueta, Carmen, Javier Belda, F., Librero, Julian, Tusman, Gerardo, Suarez-Sipmann, Fernando, Peiro, Salvador, Pozo, Natividad, Brunelli, Andrea, Garutti, Ignacio, Gallego, Clara, Rodriguez, Aurelio, Ignacio Garcia, Jose, Diaz-Cambronero, Oscar, Balust, Jaume, Redondo, Francisco J., de la Matta, Manuel, Gallego-Ligorit, Lucia, Hernandez, Javier, Martinez, Pascual, Perez, Ana, Leal, Sonsoles, Alday, Enrique, Monedero, Pablo, Gonzalez, Rafael, Mazzirani, Guido, Aguilar, Gerardo, Lopez-Baamonde, Manuel, Felipe, Mar, Mugarra, Ana, Torrente, Jara, Valencia, Lucia, Varon, Viviana, Sanchez, Sergio, Rodriguez, Benigno, Martin, Ana, India, Inmaculada, Azparren, Gonzalo, Molina, Rodrigo, Villar, Jesus, Soro, Marina, Acosta, Jesus, Jose Alberola, Maria, Alcon, Amalia, Almajano, Rosa, Alvarez, Carlos, Anaya, Rafael, Aragon, Cristian, Argilaga, Marta, Arocas, Blanca, Ayas, Begona, Balandron, Victor, Barcena, Elizabeth, Bejarano, Natalia, Belmonte, Luis, Berges, Vanesa, Guillen Bermejo, Ma, Cabadas, Rafael, Cabrera, Sergio, Callejas, Raquel, Carbonell, Jose, Carrizo, Juan, Castillo, Jesus, Charco, Pedro, Colas, Ana, Colomina, Lorena, Cotter, Laura, Cruz, Patricia, Cuervo, Javier, Del Castillo, Gema, Del Rio, Elena, Delgado, Juan, Dexeus, Carlos, Diaz, Ruben, Dinu, Mandalina, Duca, Alejandro, Duque, Paula, Echarri, Gemma, Fabra, Patricia, Fernandez, Carmen, Florea, Raluca, Forcada, Pilar, Fuentes, Isabel, Garces, Cristina, Garcia Del Valle, Santiago, Garcia, Beatriz, Garcia, Esther, Garcia, Maria, Garcia, Mercedes, Garrigues, Beatriz, Gil, Fernando, Gonzalez, Domingo, Gracia, Alejandro, Gracia, Estefania, Cranell, Manuel, Guerra, Yessica, Gutierrez, Andrea, Hernando, Julia, Herrero, Miriam, Ibanez, Maite, Imaz, Ines, Izquierdo, Blanca, Jurado, Ana, Lafuente, Noelia, Lascorz, Laura, Leon, Irene, Lopez, Antonio, Lopez-Herrera, Daniel, Lozano, Angels, Miguel Marcos, Jose, Martinez, Graciela, Martinez, Sara, Mata, Esperanza, Matoses, Salome, Mendez, Rosa, Merino, Maria, Millaruelo, Andres, Rodrigo Molina, Carlos, Monleon, Berta, Mauricio Montenegro, Omar, Luis Munoz, Jose, Oliver-Fornies, Pablo, Ortega, Manuel, Aranzazu Palencia, Maria, Parera, Ana, Pastor, Emesto, del Mar Perez, Ma, Perez, Sara, Pestana, David, Pinol, Santiago, Puig, Jaume, Pujol, Roger, Quesada, Natividad, Ramon, Ana, Rego, Consuelo, Reviriego, Laura, Rodriguez, Rayco, Romero, Blanca, Romero, Esther, Rosello, Marta, Rovira, Lucas, Ruiz, Lola, Sancho, Laura, Sandin, Francisco, Serralta, Ferran, Tres, Eva, Valls, Paola, Vaquero, Laura, Varela, Marina, Vega, Victor, Viguera, Laura, Villazala, Ruben, Villena, Abigail, Visiedo, Sara, Ferrando, Carlos, Aldecoa, Cesar, Unzueta, Carmen, Javier Belda, F., Librero, Julian, Tusman, Gerardo, Suarez-Sipmann, Fernando, Peiro, Salvador, Pozo, Natividad, Brunelli, Andrea, Garutti, Ignacio, Gallego, Clara, Rodriguez, Aurelio, Ignacio Garcia, Jose, Diaz-Cambronero, Oscar, Balust, Jaume, Redondo, Francisco J., de la Matta, Manuel, Gallego-Ligorit, Lucia, Hernandez, Javier, Martinez, Pascual, Perez, Ana, Leal, Sonsoles, Alday, Enrique, Monedero, Pablo, Gonzalez, Rafael, Mazzirani, Guido, Aguilar, Gerardo, Lopez-Baamonde, Manuel, Felipe, Mar, Mugarra, Ana, Torrente, Jara, Valencia, Lucia, Varon, Viviana, Sanchez, Sergio, Rodriguez, Benigno, Martin, Ana, India, Inmaculada, Azparren, Gonzalo, Molina, Rodrigo, Villar, Jesus, Soro, Marina, Acosta, Jesus, Jose Alberola, Maria, Alcon, Amalia, Almajano, Rosa, Alvarez, Carlos, Anaya, Rafael, Aragon, Cristian, Argilaga, Marta, Arocas, Blanca, Ayas, Begona, Balandron, Victor, Barcena, Elizabeth, Bejarano, Natalia, Belmonte, Luis, Berges, Vanesa, Guillen Bermejo, Ma, Cabadas, Rafael, Cabrera, Sergio, Callejas, Raquel, Carbonell, Jose, Carrizo, Juan, Castillo, Jesus, Charco, Pedro, Colas, Ana, Colomina, Lorena, Cotter, Laura, Cruz, Patricia, Cuervo, Javier, Del Castillo, Gema, Del Rio, Elena, Delgado, Juan, Dexeus, Carlos, Diaz, Ruben, Dinu, Mandalina, Duca, Alejandro, Duque, Paula, Echarri, Gemma, Fabra, Patricia, Fernandez, Carmen, Florea, Raluca, Forcada, Pilar, Fuentes, Isabel, Garces, Cristina, Garcia Del Valle, Santiago, Garcia, Beatriz, Garcia, Esther, Garcia, Maria, Garcia, Mercedes, Garrigues, Beatriz, Gil, Fernando, Gonzalez, Domingo, Gracia, Alejandro, Gracia, Estefania, Cranell, Manuel, Guerra, Yessica, Gutierrez, Andrea, Hernando, Julia, Herrero, Miriam, Ibanez, Maite, Imaz, Ines, Izquierdo, Blanca, Jurado, Ana, Lafuente, Noelia, Lascorz, Laura, Leon, Irene, Lopez, Antonio, Lopez-Herrera, Daniel, Lozano, Angels, Miguel Marcos, Jose, Martinez, Graciela, Martinez, Sara, Mata, Esperanza, Matoses, Salome, Mendez, Rosa, Merino, Maria, Millaruelo, Andres, Rodrigo Molina, Carlos, Monleon, Berta, Mauricio Montenegro, Omar, Luis Munoz, Jose, Oliver-Fornies, Pablo, Ortega, Manuel, Aranzazu Palencia, Maria, Parera, Ana, Pastor, Emesto, del Mar Perez, Ma, Perez, Sara, Pestana, David, Pinol, Santiago, Puig, Jaume, Pujol, Roger, Quesada, Natividad, Ramon, Ana, Rego, Consuelo, Reviriego, Laura, Rodriguez, Rayco, Romero, Blanca, Romero, Esther, Rosello, Marta, Rovira, Lucas, Ruiz, Lola, Sancho, Laura, Sandin, Francisco, Serralta, Ferran, Tres, Eva, Valls, Paola, Vaquero, Laura, Varela, Marina, Vega, Victor, Viguera, Laura, Villazala, Ruben, Villena, Abigail, and Visiedo, Sara

Abstract

Background: We aimed to examine whether using a high fraction of inspired oxygen (FIO2) in the context of an individualised intra- and postoperative open-lung ventilation approach could decrease surgical site infection (SSI) in patients scheduled for abdominal surgery. Methods: We performed a multicentre, randomised controlled clinical trial in a network of 21 university hospitals from June 6, 2017 to July 19, 2018. Patients undergoing abdominal surgery were randomly assigned to receive a high (0.80) or conventional (0.3) FIO2 during the intraoperative period and during the first 3 postoperative hours. All patients were mechanically ventilated with an open-lung strategy, which included recruitment manoeuvres and individualised positive end-expiratory pressure for the best respiratory-system compliance, and individualised continuous postoperative airway pressure for adequate peripheral oxyhaemoglobin saturation. The primary outcome was the prevalence of SSI within the first 7 postoperative days. The secondary outcomes were composites of systemic complications, length of intensive care and hospital stay, and 6-month mortality. Results: We enrolled 740 subjects: 371 in the high FIO2 group and 369 in the low FIO2 group. Data from 717 subjects were available for final analysis. The rate of SSI during the first postoperative week did not differ between high (8.9%) and low (9.4%) FIO2 groups (relative risk [RR]: 0.94; 95% confidence interval [CI]: 0.59-1.50; P=0.90]). Secondary outcomes, such as atelectasis (7.7% vs 9.8%; RR: 0.77; 95% CI: 0.48-1.25; P=0.38) and myocardial ischaemia (0.6% [n=2] vs 0% [n=0]; P=0.47) did not differ between groups. Conclusions: An oxygenation strategy using high FIO2 compared with conventional FIO2 did not reduce postoperative SSIs in abdominal surgery. No differences in secondary outcomes or adverse events were found.

Published
2020
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19. Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy: a randomised controlled trial

Author

Ferrando, Carlos, primary, Aldecoa, César, additional, Unzueta, Carmen, additional, Belda, F. Javier, additional, Librero, Julián, additional, Tusman, Gerardo, additional, Suárez-Sipmann, Fernando, additional, Peiró, Salvador, additional, Pozo, Natividad, additional, Brunelli, Andrea, additional, Garutti, Ignacio, additional, Gallego, Clara, additional, Rodríguez, Aurelio, additional, García, Jose Ignacio, additional, Díaz-Cambronero, Oscar, additional, Balust, Jaume, additional, Redondo, Francisco J., additional, de la Matta, Manuel, additional, Gallego-Ligorit, Lucía, additional, Hernández, Javier, additional, Martínez, Pascual, additional, Pérez, Ana, additional, Leal, Sonsoles, additional, Alday, Enrique, additional, Monedero, Pablo, additional, González, Rafael, additional, Mazzirani, Guido, additional, Aguilar, Gerardo, additional, López-Baamonde, Manuel, additional, Felipe, Mar, additional, Mugarra, Ana, additional, Torrente, Jara, additional, Valencia, Lucia, additional, Varón, Viviana, additional, Sánchez, Sergio, additional, Rodríguez, Benigno, additional, Martín, Ana, additional, India, Inmaculada, additional, Azparren, Gonzalo, additional, Molina, Rodrigo, additional, Villar, Jesús, additional, Soro, Marina, additional, Acosta, Jesús, additional, Alberola, María J., additional, Alcón, Amalia, additional, Almajano, Rosa, additional, Álvarez, Carlos, additional, Anaya, Rafael, additional, Aragón, Cristian, additional, Argilaga, Marta, additional, Arocas, Blanca, additional, Ayas, Begoña, additional, Balandrón, Victor, additional, Bárcena, Elizabeth, additional, Bejarano, Natalia, additional, Belmonte, Luis, additional, Berges, Vanesa, additional, Guillén Bermejo, Maria, additional, Cabadas, Rafael, additional, Cabrera, Sergio, additional, Callejas, Raquel, additional, Carbonell, Jose, additional, Carrizo, Juan, additional, Castillo, Jesús, additional, Charco, Pedro, additional, Colás, Ana, additional, Colomina, Lorena, additional, Cotter, Laura, additional, Cruz, Patricia, additional, Cuervo, Javier, additional, Del Castillo, Gema, additional, Del Río, Elena, additional, Delgado, Juan, additional, Dexeus, Carlos, additional, Díaz, Rubén, additional, Dinu, Mandalina, additional, Duca, Alejandro, additional, Duque, Paula, additional, Echarri, Gemma, additional, Fabra, Patricia, additional, Fernández, Carmen, additional, Florea, Raluca, additional, Forcada, Pilar, additional, Fuentes, Isabel, additional, Garcés, Cristina, additional, Del Valle, Santiago G., additional, García, Beatriz, additional, García, Esther, additional, García, María, additional, García, Mercedes, additional, Garrigues, Beatriz, additional, Gil, Fernando, additional, González, Domingo, additional, Gracia, Alejandro, additional, Gracia, Estefanía, additional, Granell, Manuel, additional, Guerra, Yessica, additional, Gutierrez, Andrea, additional, Hernando, Julia, additional, Herrero, Miriam, additional, Ibáñez, Maite, additional, Imaz, Inés, additional, Izquierdo, Blanca, additional, Jurado, Ana, additional, Lafuente, Noelia, additional, Lascorz, Laura, additional, León, Irene, additional, López, Antonio, additional, López-Herrera, Daniel, additional, Lozano, Angels, additional, Marcos, José M., additional, Martínez, Graciela, additional, Martínez, Sara, additional, Mata, Esperanza, additional, Matoses, Salomé, additional, Mendez, Rosa, additional, Merino, María, additional, Millaruelo, Andrés, additional, Molina, Carlos R., additional, Monleon, Berta, additional, Montenegro, Omar M., additional, Muñoz, Jose L., additional, Oliver-Forniés, Pablo, additional, Ortega, Manuel, additional, Palencia, María A., additional, Parera, Ana, additional, Pastor, Ernesto, additional, del Mar Pérez, Maria, additional, Pérez, Sara, additional, Pestaña, David, additional, Piñol, Santiago, additional, Puig, Jaume, additional, Pujol, Roger, additional, Quesada, Natividad, additional, Ramón, Ana, additional, Rego, Consuelo, additional, Reviriego, Laura, additional, Rodríguez, Rayco, additional, Romero, Blanca, additional, Romero, Esther, additional, Roselló, Marta, additional, Rovira, Lucas, additional, Ruiz, Lola, additional, Sancho, Laura, additional, Sandín, Francisco, additional, Serralta, Ferran, additional, Tres, Eva, additional, Valls, Paola, additional, Vaquero, Laura, additional, Varela, Marina, additional, Vega, Victor, additional, Viguera, Laura, additional, Villazala, Rubén, additional, Villena, Abigail, additional, and Visiedo, Sara, additional

Published
2020
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22. Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE) : a randomised controlled trial

Author

Ferrando, Carlos, Soro, Marina, Unzueta, Carmen, Suarez-Sipmann, Fernando, Canet, Jaume, Librero, Julian, Pozo, Natividad, Peiro, Salvador, Llombart, Alicia, Leon, Irene, India, Inmaculada, Aldecoa, Cesar, Diaz-Cambronero, Oscar, Pestana, David, Redondo, Francisco J., Garutti, Ignacio, Balust, Jaume, Garcia, Jose I., Ibanez, Maite, Granell, Manuel, Rodriguez, Aurelio, Gallego, Lucia, de la Matta, Manuel, Gonzalez, Rafael, Brunelli, Andrea, Garcia, Javier, Rovira, Lucas, Barrios, Francisco, Torres, Vicente, Hernandez, Samuel, Gracia, Estefania, Gine, Marta, Garcia, Maria, Garcia, Nuria, Miguel, Lisset, Sanchez, Sergio, Pineiro, Patricia, Pujol, Roger, Garcia-del-Valle, Santiago, Valdivia, Jose, Hernandez, Maria J., Padron, Oto, Colas, Ana, Puig, Jaume, Azparren, Gonzalo, Tusman, Gerardo, Villar, Jesus, Belda, Javier, Ferrando, Carlos, Soro, Marina, Unzueta, Carmen, Suarez-Sipmann, Fernando, Canet, Jaume, Librero, Julian, Pozo, Natividad, Peiro, Salvador, Llombart, Alicia, Leon, Irene, India, Inmaculada, Aldecoa, Cesar, Diaz-Cambronero, Oscar, Pestana, David, Redondo, Francisco J., Garutti, Ignacio, Balust, Jaume, Garcia, Jose I., Ibanez, Maite, Granell, Manuel, Rodriguez, Aurelio, Gallego, Lucia, de la Matta, Manuel, Gonzalez, Rafael, Brunelli, Andrea, Garcia, Javier, Rovira, Lucas, Barrios, Francisco, Torres, Vicente, Hernandez, Samuel, Gracia, Estefania, Gine, Marta, Garcia, Maria, Garcia, Nuria, Miguel, Lisset, Sanchez, Sergio, Pineiro, Patricia, Pujol, Roger, Garcia-del-Valle, Santiago, Valdivia, Jose, Hernandez, Maria J., Padron, Oto, Colas, Ana, Puig, Jaume, Azparren, Gonzalo, Tusman, Gerardo, Villar, Jesus, and Belda, Javier

Abstract

Background The effects of individualised perioperative lung-protective ventilation (based on the open-lung approach [OLA]) on postoperative complications is unknown. We aimed to investigate the effects of intraoperative and postoperative ventilatory management in patients scheduled for abdominal surgery, compared with standard protective ventilation. Methods We did this prospective, multicentre, randomised controlled trial in 21 teaching hospitals in Spain. We enrolled patients who were aged 18 years or older, were scheduled to have abdominal surgery with an expected time of longer than 2 h, had intermediate-to-high-risk of developing postoperative pulmonary complications, and who had a body-mass index less than 35 kg/m(2). Patients were randomly assigned (1: 1: 1: 1) online to receive one of four lung-protective ventilation strategies using low tidal volume plus positive end-expiratory pressure (PEEP): open-lung approach (OLA)-iCPAP (individualised intraoperative ventilation [individualised PEEP after a lung recruitment manoeuvre] plus individualised postoperative continuous positive airway pressure [CPAP]), OLA-CPAP (intraoperative individualised ventilation plus postoperative CPAP), STD-CPAP (standard intraoperative ventilation plus postoperative CPAP), or STD-O-2 (standard intraoperative ventilation plus standard postoperative oxygen therapy). Patients were masked to treatment allocation. Investigators were not masked in the operating and postoperative rooms; after 24 h, data were given to a second investigator who was masked to allocations. The primary outcome was a composite of pulmonary and systemic complications during the first 7 postoperative days. We did the primary analysis using the modified intention-to-treat population. This trial is registered with ClinicalTrials.gov, number NCT02158923. Findings Between Jan 2, 2015, and May 18, 2016, we enrolled 1012 eligible patients. Data were available for 967 patients, whom we included in the final analysis. Ris

Published
2018
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23. Observational acute pain study in admitted patients of a tertiary hospital in Spain

Author

Rovira, Lucas

Abstract

Title:Observational acute pain study in admitted patients of a tertiary hospital in SpainAuthor(s):Rovira L.1, Alcover L.1, Mazzinari G.1, Collado B.1, Madrid E.2, Romero E.1Institute(s):1Hospital de Manises, Dept of Anaesthesiology & Pain Medicine, Manises, Spain,2Universidad Catu00f3lica de Valencia San Vicente Mu00e1rtir, Facultad Medicina y Odontologu00eda, Valencia, SpainText:Background:There are numerous sources that highlight the undertreatment of pain in hospitalized patients.This is not only a need but a right for patients. Many scientific societies guarantee it, including the Joint Commission on Accreditation of Healthcare Organization (JCAHO) with support from WHO.Pain is considered the fifth clinical constant [1]. The current status of pain in our hospital, is vital to plan and develop strategies in order to follow a Pain free Hospital.Methods:An observational cross-sectional study was performed for 7 consecutive days to all patients admitted to a tertiary hospital of 300 beds. acute pain was collected by visual analog scale (VAS) at rest and in motion, VAS measurements were performed every 8 hours to all patients admitted, which generated more than 1350 VAS measurements of pain. Other variables of interest as the specific analgesic treatment (locoregional techniques),rescue analgesic medication administered, as well as sex, age, reason for admission, and specialty care was collected. Data was processed by SPSS v22 (IBM).Results:246 patients (149 surgical and 97 medical) were evaluated, the prevalence of episodes of moderate to severe pain (VAS> 4) was 53% (132/246) of all patients admitted.69% of surgical patients and 30% of medical patients underwent moderate-severe pain episodes.The average number of episodes (VAS> 4) occurred 1.45 u00b12.0 times.The results showed an average pain VAS of 1.69 u00b1 1.96 IC95{0,5.6} at rest and 2.42 u00b1 2.49 IC95{0,7.4} in motion.Rescue medication was administered to 38% of the observed patients (20% medical and 25% of surgical patients) .Being acetaminophen the most used drug.7.3% of all hospitalized patients received specific analgesic techniques 18/246. Corresponding to 1.6% (7) of medical patients and 5.7% (11) of surgical patients.Discussion:The data are consistent with similar studies in other centers [2], however, these data are far from the goal of

Published
2017

24. Diaphragm Ultrasound As A Predictor Of Patients At Risk Of Pulmonary Postoperative Complications After Phrenic Nerve Compromise

Author

Rovira, Lucas

Abstract

Diaphragm ultrasound as a predictor of patients at risk of pulmonary postoperative complications after phrenic nerve compromise.L. Rovira Soriano, P. Kot, I. Leon, J. Hernandez, S. Pozo , J. De Andres1Hospital General Universitario de Valencia - Valencia (Spain)Background and Goal of Study:In some patient, procedures(anesthetic or surgical) that could produce phrenic nerve palsy should be avoided because it produces ipsilateral hemidiaphragm palsy, this significantly reduces FVC and FEV1 by 30%.Currently, the use of diaphragmatic ultrasound applied duringweaning in critical care patients has shown that after unilateral phrenic nerve injury, extubation was possible when there was a contralateral health hemidiaphragm with at least diaphragmatic thickening Fraction (DTF)>30%(1) and diaphragmatic excursion (DE)>25mm. Diaphragm evaluation using DTF and DE during the perioperative period can be useful in detecting patients at risk of suffering postoperative pulmonary complications(PPC) if hemidiaphragm palsy occurs.Materials and Methods: We conducted an observational study in 6 patients with ipsilateral hemidiaphragm palsy due to interscalenic block(ISB) for shoulder surgery at post-anesthesia care unit (PACU). In all the patients DTF and DE were obtained pre and postoperative. DTF was calculated measuring diaphragm thick at TLC and FRC in aposition zone(5-8th intercostal space at axillary line) with a linear 12Mhz probe. DE measures diaphragm movement with a convex 3-5 Mhz probe at subcostal space; we recorded SaO2/FiO2,FR, and PPC at PACU.Results and Discussion: The echographic evaluation of the diaphragm lasted 8u00b13 minutes. 83% of patients (5/6) has postoperative complete palsy of ipsilateral hemidiaphragm after ISB. But only 16% of patients (1/6) has postoperative pulmonary complications. Patient ID2 has Dyspnoea, tachypnoea of 34 rpm, and SaO2/FiO2 reduction from 466 to 247 at PACU. Diaphragm evaluation of ID2 shows DTF=28% and DE=14mm. In this small case report series study, patients with ipsilateral hemidiaphragm palsy after ISBwere common, this fact didnu00b4t produce PPC because contralateral healthy hemidiaphragm has DTF>30% and DE>25mm. the only patient with PPC has DTF

Published
2017

25. Evaluation of three intervention to reduce emergency department utilization following tonsillectomy

Author

Rovira, Lucas

Abstract

Title:Evaluation of three intervention to reduce emergency department utilization following tonsillectomyAuthor(s):Rovira L.1, Beaus B.2, Collado B.1, Pozo S.3, Santa Cruz M.4, Casinos E.4Institute(s):1Hospital de Manises, Dept of Anaesthesiology & Pain Medicine, Manises, Spain, 2Hospital de Manises, Department of Otorhinolaryngology, Manises, Spain, 3Consorcio Hospital General Universitario de Valencia, Nurse, Valencia, Spain, 4Hospital de Manises, Nurse, Manises, SpainText:Background: Patients undergoing tonsillectomy may suffer acute postoperative pain up to 14 days.In selected patients the surgery is performed on an outpatient basis but pain related complications are common and they need emergency department (ED) treatment for pain and / or dehydration. Bleeding is also a common cause of consultation after this procedure. we observe if a particular perioperative analgesic and home treatment, associated with educational interventions can reduce the rate of ED consultation.Methods: Three main interventions are performed:1-Pre and postoperative education including detection of alarm signs, need to take prescribed drugs and type of food that patients should eat (soft diet and cold liquids)2-Adequate perioperative analgesia (adding dexamethasone 0.5mg /kg)3-Changing the home analgesic regimen for maximum drug efficacy during ingest: acetaminophen an hour before meal and ibuprofen 30 minutes before meal.We retrospectively compare the rate of ED consultation related to post-tonsillectomy pain and bleeding causes. all consultations for these causes are collected one year (2014) before implementing these new interventions and one year (2015) after implement them.Data are compared using chi-square test using SPSS V22 (IBM).Results and discussion: tTYPE OF CONSULTATIONYEARtPAINtBLEEDING2014t12,9% (22/171)t7,0% (12/171)2015t9,4% (9/96)t8,3% (9/96)u03c7 2t0.39t0.69[Consultation rate to the emergency department (ED)]Implemented interventions during 2015 compared to 2014 appears to reduce a 22% pain consultation rate.However the sample size accumulated to date does not allow finding significant differences, being necessary to increase it to n=800 to confirm this hypothesis.Bleeding does not seem to increase with this interventions as evidenced in other articles (1, 2)Conclusion: Apply educational interventions as well as modify analgesic drugs regimen could reduce the rate of pain consultation at ED, further studies with larger sample size are guaranteed.References: 1. Bellis JR, et al Dexamethasone and haemorrhage risk in paediatric tonsillectomy: a systematic review and meta-analysis.Br J Anaesth. 2014 Jul;113(1):23-42.2. Bedwell JR et al. Ibuprofen with acetaminophen for postoperative pain control following tonsillectomy does not increase emergency department utilization.Otolaryngol Head Neck Surg. 2014 Dec;151(6):963-6Ethical Research Declaration:2. Retrospective data review

Published
2017

29. Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE): a randomised controlled trial

Author

Ferrando, Carlos, primary, Soro, Marina, additional, Unzueta, Carmen, additional, Suarez-Sipmann, Fernando, additional, Canet, Jaume, additional, Librero, Julián, additional, Pozo, Natividad, additional, Peiró, Salvador, additional, Llombart, Alicia, additional, León, Irene, additional, India, Inmaculada, additional, Aldecoa, Cesar, additional, Díaz-Cambronero, Oscar, additional, Pestaña, David, additional, Redondo, Francisco J, additional, Garutti, Ignacio, additional, Balust, Jaume, additional, García, Jose I, additional, Ibáñez, Maite, additional, Granell, Manuel, additional, Rodríguez, Aurelio, additional, Gallego, Lucía, additional, de la Matta, Manuel, additional, Gonzalez, Rafael, additional, Brunelli, Andrea, additional, García, Javier, additional, Rovira, Lucas, additional, Barrios, Francisco, additional, Torres, Vicente, additional, Hernández, Samuel, additional, Gracia, Estefanía, additional, Giné, Marta, additional, García, María, additional, García, Nuria, additional, Miguel, Lisset, additional, Sánchez, Sergio, additional, Piñeiro, Patricia, additional, Pujol, Roger, additional, García-del-Valle, Santiago, additional, Valdivia, José, additional, Hernández, María J, additional, Padrón, Oto, additional, Colás, Ana, additional, Puig, Jaume, additional, Azparren, Gonzalo, additional, Tusman, Gerardo, additional, Villar, Jesús, additional, Belda, Javier, additional, Acosta, Jesús, additional, Aguilar, Gerardo, additional, Alberola, María José, additional, Alcón, Amalia, additional, Alonso, Jose M., additional, Alonso, María Dolores, additional, Anaya, Rafael, additional, Argente, María Pilar, additional, Agilaga, Marta, additional, Arocas, Blanca, additional, Asensio, Ana, additional, Ayas, Begoña, additional, Ayuso, Mercedes, additional, Balandrón, Victor, additional, Barrio, María, additional, Bejarano, Natalia, additional, Benítez, Inmaculada, additional, Cabrera, Sergio, additional, Carbonell, Jose A., additional, Carramiñana, Albert, additional, Carrizo, Juan, additional, Cegarra, Virginia, additional, Chamorro, Estefanía, additional, Charco, Pedro, additional, Cruz, Patricia, additional, Daviu, Francisco, additional, De Fez, Mario, additional, De Miguel, Ángeles, additional, Del Río, Elena, additional, Delgado, Carlos, additional, Díaz, Ruben, additional, Díaz, Susana, additional, Díez, Fernando, additional, Dosdá, Rosa, additional, Duca, Alejandro, additional, Etulain, Ma Justina, additional, Fernández, Carmen, additional, Franco, Tania, additional, Fuentes, Isabel, additional, Gallego, Clara, additional, Gallego-Casilda, Alberto, additional, Galve, Ana Isabel, additional, Garcés, Cristina, additional, García, Mercedes, additional, García, Pablo, additional, Garrigues, Beatriz, additional, Gilabert, Vicente, additional, González, Domingo, additional, Gutiérrez, Andrea, additional, Hernández, Inmaculada, additional, Izquierdo, Ana, additional, Jurado, Ana, additional, Katime, Antonio, additional, Llamazares, Eduardo, additional, Lardies, Rosa, additional, Lisbona, Cristina, additional, López-Herrera, Daniel, additional, López, Ramiro, additional, Lozano, Angels, additional, Lozano, Elena, additional, Marcos, Jose Miguel, additional, Martin, Silvia, additional, Martínez, Nilda, additional, Martínez, Rocío, additional, Martínez-Pallí, Graciella, additional, Mazzinari, Guido, additional, Miñana, Amanda, additional, Moral, Victoria, additional, Moreno, Tania, additional, Mugarra, Ana, additional, Muñoz, Lorena, additional, Navarro, Jose, additional, Olmedilla, Luis, additional, Olmedo, Jonathan, additional, Ojeda, Nazario, additional, Parera, Ana, additional, Parra, María, additional, Parrilla, Cristina, additional, Pastor, Ernesto, additional, Peña, Natalia, additional, Pérez, Ana María, additional, Pérez, Jose María, additional, Piqueras, Laura, additional, Rico-Feijoo, Jesús, additional, Rodríguez, Rayco, additional, Román, Javier Ignacio, additional, Romero, Antonio, additional, Romero, Carolina, additional, Romero, Esther, additional, Ruiz, Isabel, additional, Sánchez, Ester, additional, Sandín, Francisco, additional, Serralta, Ferran, additional, Socorro, Tania, additional, Soriano, Laura, additional, Tisner, Manuel, additional, Valencia, Lucia, additional, Valls, Paola, additional, Vaquero, Laura, additional, Varón, Viviana, additional, Vila, María, additional, Villazala, Rubén, additional, Villena, Abigail, additional, and Zapatero, Sara, additional

Published
2018
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32. Rationale and study design for an individualized perioperative open lung ventilatory strategy (iPROVE) : study protocol for a randomized controlled trial

Author

Ferrando, Carlos, Soro, Marina, Canet, Jaume, Carmen Unzueta, Ma, Suarez-Sipmann, Fernando, Librero, Julian, Peiro, Salvador, Llombart, Alicia, Delgado, Carlos, Leon, Irene, Rovira, Lucas, Ramasco, Fernando, Granell, Manuel, Aldecoa, Cesar, Diaz, Oscar, Balust, Jaume, Garutti, Ignacio, de la Matta, Manuel, Pensado, Alberto, Gonzalez, Rafael, Eugenia Duran, Ma, Gallego, Lucia, Garcia del Valle, Santiago, Redondo, Francisco J., Diaz, Pedro, Pestana, David, Rodriguez, Aurelio, Aguirre, Javier, Garcia, Jose M., Garcia, Javier, Espinosa, Elena, Charco, Pedro, Navarro, Jose, Rodriguez, Clara, Tusman, Gerardo, Javier Belda, Francisco, Ferrando, Carlos, Soro, Marina, Canet, Jaume, Carmen Unzueta, Ma, Suarez-Sipmann, Fernando, Librero, Julian, Peiro, Salvador, Llombart, Alicia, Delgado, Carlos, Leon, Irene, Rovira, Lucas, Ramasco, Fernando, Granell, Manuel, Aldecoa, Cesar, Diaz, Oscar, Balust, Jaume, Garutti, Ignacio, de la Matta, Manuel, Pensado, Alberto, Gonzalez, Rafael, Eugenia Duran, Ma, Gallego, Lucia, Garcia del Valle, Santiago, Redondo, Francisco J., Diaz, Pedro, Pestana, David, Rodriguez, Aurelio, Aguirre, Javier, Garcia, Jose M., Garcia, Javier, Espinosa, Elena, Charco, Pedro, Navarro, Jose, Rodriguez, Clara, Tusman, Gerardo, and Javier Belda, Francisco

Abstract

Background: Postoperative pulmonary and non-pulmonary complications are common problems that increase morbidity and mortality in surgical patients, even though the incidence has decreased with the increased use of protective lung ventilation strategies. Previous trials have focused on standard strategies in the intraoperative or postoperative period, but without personalizing these strategies to suit the needs of each individual patient and without considering both these periods as a global perioperative lung-protective approach. The trial presented here aims at comparing postoperative complications when using an individualized ventilatory management strategy in the intraoperative and immediate postoperative periods with those when using a standard protective ventilation strategy in patients scheduled for major abdominal surgery. Methods: This is a comparative, prospective, multicenter, randomized, and controlled, four-arm trial that will include 1012 patients with an intermediate or high risk for postoperative pulmonary complications. The patients will be divided into four groups: (1) individualized perioperative group: intra-and postoperative individualized strategy; (2) intraoperative individualized strategy + postoperative continuous positive airway pressure (CPAP); (3) intraoperative standard ventilation + postoperative CPAP; (4) intra-and postoperative standard strategy (conventional strategy). The primary outcome is a composite analysis of postoperative complications. Discussion: The Individualized Perioperative Open-lung Ventilatory Strategy (iPROVE) is the first multicenter, randomized, and controlled trial to investigate whether an individualized perioperative approach prevents postoperative pulmonary complications.

Published
2015
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33. La pesca con palangre pelágico en el Pacifico panameño. Aspectos operativos de la selectividad de los anzuelos y repercusiones en la captura incidental de tortugas marinas

Author

Pacheco Rovira, Lucas Ramiro, Universidad de Alicante. Departamento de Ciencias del Mar y Biología Aplicada, Hall, Martín, and Camiñas, Juan A.

Subjects
Pacífico, Selectividad, Gestión pesquera, Palangre
Abstract

Máster Internacional en GESTIÓN PESQUERA SOSTENIBLE (4ª edición: 2011-2013) Con el objetivo general de valorar si el uso de anzuelos circulares contribuiría a la reducción de capturas incidentales de tortugas marinas en la pesquería de palangre que se realiza en la ZEE de la República de Panamá, el programa creado con ese objetivo por un grupo de organizaciones entre estas ASOEXPEBLA, CIAT y WWF, propuso a la flota palangrera, realizar intercambios de anzuelos tradicionales (J y circular tamaño 14/0) por anzuelos circulares de mayor tamaño (15/0 y 16/0). A través de la implementación de un programa de observadores pesqueros a bordo se pudo experimentar (entre 2005 – 2009) con diversos tamaños de anzuelos circulares y se recopiló la información referente a las capturas de especies objetivas de la pesca y no objetivas. Se analizó la información pesquera de 796 lances en donde se usaron un total de 508,553 anzuelos en la pesca dirigida a la captura del Atún aleta amarilla (Thunnus albacares) y del Dorado (Coryphaena hippurus), probando 8 combinaciones de anzuelos. El 98,5 % de las tortugas marinas capturadas incidentalmente fueron recuperadas con vida al momento de la virada del palangre. Los análisis muestran diversos resultados para cada combinación de anzuelos analizada. En la pesca del Atún aleta amarilla el anzuelo C16 reduce significativamente la CPUE de L. olivacea con respecto al anzuelo tradicional J, y el C15 presenta una reducción de CPUE marginalmente significativas frente al J. En la pesca del Dorado, el anzuelo C16 reduce significativamente la CPUE de tortugas marinas con respecto al anzuelo C15 (p-valor 0,003). Las reducciones en la CPUE de las especies Chelonia mydas y C. mydas agassizii se detectaron en las combinaciones C15 vs C14 y C15 vs C13 y fueron significativamente menores con los anzuelos de menor tamaño C14 (p-valor 0,036) y C13 (p-valor 0,05) frente al anzuelo C15.

Published
2013

35. La pesca con palangre pelágico en el Pacifico panameño. Aspectos operativos de la selectividad de los anzuelos y repercusiones en la captura incidental de tortugas marinas

Author

Hall, Martín, Camiñas, Juan A., Universidad de Alicante. Departamento de Ciencias del Mar y Biología Aplicada, Pacheco Rovira, Lucas Ramiro, Hall, Martín, Camiñas, Juan A., Universidad de Alicante. Departamento de Ciencias del Mar y Biología Aplicada, and Pacheco Rovira, Lucas Ramiro

Abstract

Con el objetivo general de valorar si el uso de anzuelos circulares contribuiría a la reducción de capturas incidentales de tortugas marinas en la pesquería de palangre que se realiza en la ZEE de la República de Panamá, el programa creado con ese objetivo por un grupo de organizaciones entre estas ASOEXPEBLA, CIAT y WWF, propuso a la flota palangrera, realizar intercambios de anzuelos tradicionales (J y circular tamaño 14/0) por anzuelos circulares de mayor tamaño (15/0 y 16/0). A través de la implementación de un programa de observadores pesqueros a bordo se pudo experimentar (entre 2005 – 2009) con diversos tamaños de anzuelos circulares y se recopiló la información referente a las capturas de especies objetivas de la pesca y no objetivas. Se analizó la información pesquera de 796 lances en donde se usaron un total de 508,553 anzuelos en la pesca dirigida a la captura del Atún aleta amarilla (Thunnus albacares) y del Dorado (Coryphaena hippurus), probando 8 combinaciones de anzuelos. El 98,5 % de las tortugas marinas capturadas incidentalmente fueron recuperadas con vida al momento de la virada del palangre. Los análisis muestran diversos resultados para cada combinación de anzuelos analizada. En la pesca del Atún aleta amarilla el anzuelo C16 reduce significativamente la CPUE de L. olivacea con respecto al anzuelo tradicional J, y el C15 presenta una reducción de CPUE marginalmente significativas frente al J. En la pesca del Dorado, el anzuelo C16 reduce significativamente la CPUE de tortugas marinas con respecto al anzuelo C15 (p-valor 0,003). Las reducciones en la CPUE de las especies Chelonia mydas y C. mydas agassizii se detectaron en las combinaciones C15 vs C14 y C15 vs C13 y fueron significativamente menores con los anzuelos de menor tamaño C14 (p-valor 0,036) y C13 (p-valor 0,05) frente al anzuelo C15.

Published
2013

36. Rationale and study design for an individualized perioperative open lung ventilatory strategy (iPROVE): study protocol for a randomized controlled trial.

Author

Ferrando C, Soro M, Canet J, Unzueta MC, Suárez F, Librero J, Peiró S, Llombart A, Delgado C, León I, Rovira L, Ramasco F, Granell M, Aldecoa C, Diaz O, Balust J, Garutti I, de la Matta M, Pensado A, Gonzalez R, Durán ME, Gallego L, Del Valle SG, Redondo FJ, Diaz P, Pestaña D, Rodríguez A, Aguirre J, García JM, García J, Espinosa E, Charco P, Navarro J, Rodríguez C, Tusman G, and Belda FJ

Subjects
Clinical Protocols, Female, Humans, Lung Diseases diagnosis, Lung Diseases etiology, Lung Diseases physiopathology, Male, Perioperative Care, Postoperative Complications diagnosis, Postoperative Complications physiopathology, Prospective Studies, Research Design, Respiration, Artificial adverse effects, Spain, Time Factors, Treatment Outcome, Abdomen surgery, Continuous Positive Airway Pressure adverse effects, Lung physiopathology, Lung Diseases prevention & control, Postoperative Complications prevention & control, Respiration, Artificial methods
Abstract

Background: Postoperative pulmonary and non-pulmonary complications are common problems that increase morbidity and mortality in surgical patients, even though the incidence has decreased with the increased use of protective lung ventilation strategies. Previous trials have focused on standard strategies in the intraoperative or postoperative period, but without personalizing these strategies to suit the needs of each individual patient and without considering both these periods as a global perioperative lung-protective approach. The trial presented here aims at comparing postoperative complications when using an individualized ventilatory management strategy in the intraoperative and immediate postoperative periods with those when using a standard protective ventilation strategy in patients scheduled for major abdominal surgery., Methods: This is a comparative, prospective, multicenter, randomized, and controlled, four-arm trial that will include 1012 patients with an intermediate or high risk for postoperative pulmonary complications. The patients will be divided into four groups: (1) individualized perioperative group: intra- and postoperative individualized strategy; (2) intraoperative individualized strategy + postoperative continuous positive airway pressure (CPAP); (3) intraoperative standard ventilation + postoperative CPAP; (4) intra- and postoperative standard strategy (conventional strategy). The primary outcome is a composite analysis of postoperative complications., Discussion: The Individualized Perioperative Open-lung Ventilatory Strategy (iPROVE) is the first multicenter, randomized, and controlled trial to investigate whether an individualized perioperative approach prevents postoperative pulmonary complications., Trial Registration: Registered on 5 June 2014 with identification no. NCT02158923 .

Published
2015
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