29 results on '"Roussillon, Caroline"'
Search Results
2. Effects of azithromycin and doxycycline on the vaginal microbiota of women with urogenital Chlamydia trachomatis infection: a substudy of the Chlazidoxy randomized controlled trial
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Baita, Dounia, Ouziel-Duretz, Catherine, Poudens, Béatrice, Brun, Raquel, Jouvert, Sophie, Tesson, Aurore, Carrière, Jennifer, Diaz, Marie, Forget, Camille, Le Hen, Isabelle, Ahano-Ducourneau, France, Van, Delphine Ha, Robert, Pauline, Brun, Fabienne, Lhospital, Estelle, Bardou, Julie, Guegan, Annaïg, Moura, Sandy Ramloll, Leriche, Céline, De Cussy, Alix, Malfait, Marlène, Rychen, Charlotte, Martinet, Pervenche, Kugeler, Audrey, Barriere, Lisa, Gutierrez, Laura, Robert, Jean-Luc, Saule, Julie, Bergamaschi, Viviana, Soltana, Sana Ben, Aymar-Moulene, Dominique, Bernier, Claire, Lecompte, Anne-Sophie, Gregoire, Antoine, Girard, Thomas, Naccache, Marie-Astrid, Lefebvre, Philippe, Crombe, Pauline, Bulot, Christine, Rolland, Anne-Laure, Dernivoix, Katy, Trouillet, Camille, Trignol-Viguier, Nathalie, Blin-Zbiegiel, Elisabeth, Boissinot, Mélanie, Joly, Bruno, Dubreuil, Anne, Mathieu, Camille, Pragout, David, Bébéar, Cécile, Grob, Anne, Zaffreya, Sophie, Le Naour, Erwan, Gibaud, Anne Sophie, Lanotte, Philippe, Vachée, Anne, Loubinoux, Julien, Touati, Arabella, Balcon, Carla, Roussillon, Caroline, Ghezzoul, Bellabes, Perry, Frédéric, Turuban, Christelle, Rapin, Sabine, Pastor, Christine, Cavellec, Morane, Manvri, Ernesto Paredes, Albane, Sonia, Ghiringhelli, Eva, Pantin, Karen, Kret, Marion, Lhomme, Edouard, Garreau, Damien, Galet, Jérôme, Tamarelle, Jeanne, Penaud, Benjamin, Tyssandier, Benjamin, Guichoux, Erwan, de Barbeyrac, Bertille, and Peuchant, Olivia
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- 2023
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3. Posttraumatic stress disorder 2 months after cesarean delivery: a multicenter prospective study
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Sentilhes, Loïc, Senat, Marie V., Le Lous, Maëla, Winer, Norbert, Rozenberg, Patrick, Kayem, Gilles, Verspyck, Eric, Fuchs, Florent, Azria, Elie, Gallot, Denis, Korb, Diane, Desbrière, Raoul, Le Ray, Camille, Chauleur, Céline, de Marcillac, Fanny, Perrotin, Franck, Parant, Olivier, Salomon, Laurent J., Gauchotte, Emilie, Bretelle, Florence, Sananès, Nicolas, Bohec, Caroline, Mottet, Nicolas, Legendre, Guillaume, Letouzey, Vincent, Haddad, Bassam, Vardon, Delphine, Madar, Hugo, Mattuizzi, Aurélien, Froeliger, Alizée, Daniel, Valérie, Regueme, Sophie, Roussillon, Caroline, Bénard, Antoine, Georget, Aurore, Darsonval, Astrid, Deneux-Tharaux, Catherine, and Loussert, Lola
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- 2024
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4. Doxycycline versus azithromycin for the treatment of anorectal Chlamydia trachomatis infection in women concurrent with vaginal infection (CHLAZIDOXY study): a multicentre, open-label, randomised, controlled, superiority trial
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Ouziel-Duretz, Catherine, Poudens, Béatrice, Brun, Raquel, Jouvert, Sophie, Tesson, Aurore, Carrière, Jennifer, Diaz, Marie, Forget, Camille, Ahano-Ducourneau, France, Ha Van, Delphine, Robert, Pauline, Brun, Fabienne, Lhospital, Estelle, Bardou, Julie, Guegan, Annaïg, Ramloll Moura, Sandy, Leriche, Céline, De Cussy, Alix, Malfait, Marlène, Rychen, Charlotte, Kugeler, Audrey, Barriere, Lisa, Gutierrez, Laura, Robert, Jean-Luc, Saule, Julie, Bergamaschi, Viviana, Ben Soltana, Sana, Aymar-Moulene, Dominique, Lecompte, Anne-Sophie, Grégoire, Antoine, Naccache, Marie-Astrid, Crombe, Pauline, Bulot, Christine, Rolland, Anne-Laure, Blin-Zbiegiel, Elisabeth, Boissinot, Mélanie, Joly, Bruno, Dubreuil, Anne, Mathieu, Camille, Pragout, David, Zaffreya, Sophie, Touati, Arabella, Balcon, Carla, Perry, Frédéric, Turuban, Christelle, Rapin, Sabine, Pastor, Christine, Cavellec, Morane, Paredes Manyari, Ernesto, Albane, Soria, Dernivoix, Katy, Trouillet, Camille, Ghiringelli, Eva, Pantin, Karen, Garreau, Damien, Galet, Jérôme, Peuchant, Olivia, Lhomme, Edouard, Martinet, Pervenche, Grob, Anne, Baïta, Dounia, Bernier, Claire, Gibaud, Sophie Anne, Le Hen, Isabelle, Le Naour, Erwan, Trignol-Viguier, Nathalie, Lanotte, Philippe, Lefebvre, Philippe, Vachée, Anne, Girard, Thomas, Loubinoux, Julien, Bébéar, Cécile, Ghezzoul, Bellabes, Roussillon, Caroline, Kret, Marion, and de Barbeyrac, Bertille
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- 2022
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5. Inhaled ciclesonide for outpatient treatment of COVID-19 in adults at risk of adverse outcomes: a randomised controlled trial (COVERAGE)
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Duvignaud, Alexandre, Lhomme, Edouard, Onaisi, Racha, Sitta, Rémi, Gelley, Ambre, Chastang, Julie, Piroth, Lionel, Binquet, Christine, Dupouy, Julie, Makinson, Alain, Lefèvre, Benjamin, Naccache, Jean-Marc, Roussillon, Caroline, Landman, Roland, Wallet, Cédrick, Karcher, Sophie, Journot, Valérie, Nguyen, Duc, Pistone, Thierry, Bouchet, Stéphane, Lafon, Marie-Edith, Molimard, Mathieu, Thiébaut, Rodolphe, de Lamballerie, Xavier, Joseph, Jean-Philippe, Richert, Laura, Saint-Lary, Olivier, Djabarouti, Sarah, Wittkop, Linda, Anglaret, Xavier, and Malvy, Denis
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- 2022
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6. PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study
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Sirima, Sodiomon B, Richert, Laura, Chêne, Arnaud, Konate, Amadou T, Campion, Cécilia, Dechavanne, Sébastien, Semblat, Jean-Philippe, Benhamouda, Nadine, Bahuaud, Mathilde, Loulergue, Pierre, Ouédraogo, Alphonse, Nébié, Issa, Kabore, Moïse, Kargougou, Désiré, Barry, Aïssata, Ouattara, San Maurice, Boilet, Valérie, Allais, Florence, Roguet, Gwenaelle, Havelange, Nicolas, Lopez-Perez, Elvira, Kuppers, Alexis, Konaté, Eleine, Roussillon, Caroline, Kanté, Myriam, Belarbi, Linda, Diarra, Amidou, Henry, Noelie, Soulama, Issiaka, Ouédraogo, Amidou, Esperou, Helene, Leroy, Odile, Batteux, Frederic, Tartour, Eric, Viebig, Nicola K, Thiebaut, Rodolphe, Launay, Odile, and Gamain, Benoît
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- 2020
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7. Posttraumatic stress disorder 2 months after cesarean delivery: a multicenter prospective study
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Froeliger, Alizée, primary, Deneux-Tharaux, Catherine, additional, Loussert, Lola, additional, Madar, Hugo, additional, Sentilhes, Loïc, additional, Senat, Marie V., additional, Le Lous, Maëla, additional, Winer, Norbert, additional, Rozenberg, Patrick, additional, Kayem, Gilles, additional, Verspyck, Eric, additional, Fuchs, Florent, additional, Azria, Elie, additional, Gallot, Denis, additional, Korb, Diane, additional, Desbrière, Raoul, additional, Le Ray, Camille, additional, Chauleur, Céline, additional, de Marcillac, Fanny, additional, Perrotin, Franck, additional, Parant, Olivier, additional, Salomon, Laurent J., additional, Gauchotte, Emilie, additional, Bretelle, Florence, additional, Sananès, Nicolas, additional, Bohec, Caroline, additional, Mottet, Nicolas, additional, Legendre, Guillaume, additional, Letouzey, Vincent, additional, Haddad, Bassam, additional, Vardon, Delphine, additional, Mattuizzi, Aurélien, additional, Froeliger, Alizée, additional, Daniel, Valérie, additional, Regueme, Sophie, additional, Roussillon, Caroline, additional, Bénard, Antoine, additional, Georget, Aurore, additional, and Darsonval, Astrid, additional
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- 2024
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8. Tranexamic acid for the prevention of blood loss after cesarean among women with twins: a secondary analysis of the TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery randomized clinical trial
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Sentilhes, Loïc, Madar, Hugo, Le Lous, Maëla, Sénat, Marie Victoire, Winer, Norbert, Rozenberg, Patrick, Kayem, Gilles, Verspyck, Eric, Fuchs, Florent, Azria, Elie, Gallot, Denis, Korb, Diane, Desbrière, Raoul, Le Ray, Camille, Chauleur, Céline, de Marcillac, Fanny, Perrotin, Franck, Parant, Olivier, Salomon, Laurent J., Gauchotte, Emilie, Bretelle, Florence, Sananès, Nicolas, Bohec, Caroline, Mottet, Nicolas, Legendre, Guillaume, Letouzey, Vincent, Haddad, Bassam, Vardon, Delphine, Mattuizzi, Aurélien, Froeliger, Alizée, Bouchghoul, Hanane, Daniel, Valérie, Regueme, Sophie, Roussillon, Caroline, Georget, Aurore, Darsonval, Astrid, Benard, Antoine, and Deneux-Tharaux, Catherine
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- 2022
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9. Efficacy and safety of varenicline for smoking cessation in people living with HIV in France (ANRS 144 Inter-ACTIV): a randomised controlled phase 3 clinical trial
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Allaguy-Salachy, Hélène, Arsandaux, Julie, Aubin, Henri-Jean, Bénard, Antoine, Bernard-Henry, Claudine, Beuscart, Aurélie, Beuscart, Claude, Borgne, Anne, Bouchaud, Olivier, Brahmy, Charles, Breilh, Dominique, Cabié, André, Cateland, Claude, Chêne, Geneviève, Cheret, Antoine, Couffin-Cadiergues, Sandrine, Dautzenberg, Marie-Dominique, Dellamonica, Pierre, Denis-Kandel, Pascale, Denis-Vatant, Christine, Detilleux, Michel, Dupon, Michel, Duval, Xavier, Duvivier, Claudine, El Harrar, Brigitte, Fagard, Catherine, Fagnen Sylvaire, Marie Christine, Ferret, Samuel, Guillermet, Simone, Jacomet, Christine, Jeantils, Vincent, Katlama, Christine, Korzek, Marek, Lazaro, Estibaliz, Le Maitre, Béatrice, Lucht, Frédéric, Maquet, Marianne, Mathieu, Audrey, May, Thierry, Mercié, Patrick, Merigeaud, Sonia, Moinot, Laetitia, Molina, Jean-Michel, Morlat, Philippe, Naqvi, Alissa, Neau, Didier, Perriot, Jean, Pierre-François, Sandrine, Poizot-Martin, Isabelle, Quoix, Elisabeth, Rebillard, Matthieu, Reynes, Jacques, Roussillon, Caroline, Rosenthal, Eric, Sainte-Marie, Thierry, Salmon-Céron, Dominique, Schneider, Luminita, Simon, Anne, Soussi, Malika, Sotto, Albert, Spadone, Christian, Spire, Bruno, Taburet, Anne-Marie, Teicher, Elina, Termote, Monique, Trosini-Desert, Valery, Verdon, Renaud, Viard, Jean-Paul, Vittecoq, Daniel, Vray, Muriel, Wirth, Nathalie, Youssi, David, and Zucman, David
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- 2018
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10. Efficacy and safety of nilotinib in chronic myeloid leukaemia patients who failed to achieve a treatment‐free remission period after imatinib discontinuation: Results of the French Nilo post‐STIM study
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Dulucq, Stéphanie, primary, Rigal‐Huguet, Françoise, additional, Nicolini, Franck E., additional, Cony‐Makhoul, Pascale, additional, Escoffre‐Barbe, Martine, additional, Gardembas, Martine, additional, Legros, Laurence, additional, Rousselot, Philippe, additional, Liu, Jixing, additional, Rea, Delphine, additional, De Mas, Véronique, additional, Hayette, Sandrine, additional, Raynaud, Sophie, additional, Lacoste‐Roussillon, Caroline, additional, Robbesyn, Fanny, additional, Klein, Emilie, additional, Morisset, Stéphane, additional, Mahon, François‐Xavier, additional, and Etienne, Gabriel, additional
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- 2023
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11. Effects of azithromycin and doxycycline on the vaginal microbiota of women with urogenital Chlamydia trachomatis infection: a substudy of the Chlazidoxy randomized controlled trial
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Tamarelle, Jeanne, primary, Penaud, Benjamin, additional, Tyssandier, Benjamin, additional, Guichoux, Erwan, additional, de Barbeyrac, Bertille, additional, Peuchant, Olivia, additional, Baita, Dounia, additional, Ouziel-Duretz, Catherine, additional, Poudens, Béatrice, additional, Brun, Raquel, additional, Jouvert, Sophie, additional, Tesson, Aurore, additional, Carrière, Jennifer, additional, Diaz, Marie, additional, Forget, Camille, additional, Le Hen, Isabelle, additional, Ahano-Ducourneau, France, additional, Van, Delphine Ha, additional, Robert, Pauline, additional, Brun, Fabienne, additional, Lhospital, Estelle, additional, Bardou, Julie, additional, Guegan, Annaïg, additional, Moura, Sandy Ramloll, additional, Leriche, Céline, additional, De Cussy, Alix, additional, Malfait, Marlène, additional, Rychen, Charlotte, additional, Martinet, Pervenche, additional, Kugeler, Audrey, additional, Barriere, Lisa, additional, Gutierrez, Laura, additional, Robert, Jean-Luc, additional, Saule, Julie, additional, Bergamaschi, Viviana, additional, Ben Soltana, Sana, additional, Aymar-Moulene, Dominique, additional, Bernier, Claire, additional, Lecompte, Anne-Sophie, additional, Gregoire, Antoine, additional, Girard, Thomas, additional, Naccache, Marie-Astrid, additional, Lefebvre, Philippe, additional, Crombe, Pauline, additional, Bulot, Christine, additional, Rolland, Anne-Laure, additional, Trignol-Viguier, Nathalie, additional, Blin-Zbiegiel, Elisabeth, additional, Boissinot, Mélanie, additional, Joly, Bruno, additional, Dubreuil, Anne, additional, Mathieu, Camille, additional, Pragout, David, additional, Bébéar, Cécile, additional, Grob, Anne, additional, Zaffreya, Sophie, additional, Le Naour, Erwan, additional, Gibaud, Anne Sophie, additional, Lanotte, Philippe, additional, Vachée, Anne, additional, Loubinoux, Julien, additional, Touati, Arabella, additional, Balcon, Carla, additional, Roussillon, Caroline, additional, Ghezzoul, Bellabes, additional, Perry, Frédéric, additional, Turuban, Christelle, additional, Rapin, Sabine, additional, Pastor, Christine, additional, Cavellec, Morane, additional, Manvri, Ernesto Paredes, additional, Albane, Sonia, additional, Dernivoix, Katy, additional, Trouillet, Camille, additional, Ghiringhelli, Eva, additional, Pantin, Karen, additional, Kret, Marion, additional, Lhomme, Edouard, additional, Garreau, Damien, additional, and Galet, Jérôme, additional
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- 2023
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12. Randomized, open-label, multicenter study of azithromycin compared with doxycycline for treating anorectal Chlamydia trachomatis infection concomitant to a vaginal infection (CHLAZIDOXY study)
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Peuchant, Olivia, Lhomme, Edouard, Krêt, Marion, Ghezzoul, Bellabes, Roussillon, Caroline, Bébéar, Cécile, Perry, Frédéric, and de Barbeyrac, Bertille
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- 2019
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13. Doxycycline versus azithromycin for the treatment of anorectal Chlamydia trachomatis infection in women concurrent with vaginal infection (CHLAZIDOXY study): a multicentre, open-label, randomised, controlled, superiority trial
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Peuchant, Olivia, primary, Lhomme, Edouard, additional, Martinet, Pervenche, additional, Grob, Anne, additional, Baïta, Dounia, additional, Bernier, Claire, additional, Gibaud, Sophie Anne, additional, Le Hen, Isabelle, additional, Le Naour, Erwan, additional, Trignol-Viguier, Nathalie, additional, Lanotte, Philippe, additional, Lefebvre, Philippe, additional, Vachée, Anne, additional, Girard, Thomas, additional, Loubinoux, Julien, additional, Bébéar, Cécile, additional, Ghezzoul, Bellabes, additional, Roussillon, Caroline, additional, Kret, Marion, additional, de Barbeyrac, Bertille, additional, Ouziel-Duretz, Catherine, additional, Poudens, Béatrice, additional, Brun, Raquel, additional, Jouvert, Sophie, additional, Tesson, Aurore, additional, Carrière, Jennifer, additional, Diaz, Marie, additional, Forget, Camille, additional, Ahano-Ducourneau, France, additional, Ha Van, Delphine, additional, Robert, Pauline, additional, Brun, Fabienne, additional, Lhospital, Estelle, additional, Bardou, Julie, additional, Guegan, Annaïg, additional, Ramloll Moura, Sandy, additional, Leriche, Céline, additional, De Cussy, Alix, additional, Malfait, Marlène, additional, Rychen, Charlotte, additional, Kugeler, Audrey, additional, Barriere, Lisa, additional, Gutierrez, Laura, additional, Robert, Jean-Luc, additional, Saule, Julie, additional, Bergamaschi, Viviana, additional, Ben Soltana, Sana, additional, Aymar-Moulene, Dominique, additional, Lecompte, Anne-Sophie, additional, Grégoire, Antoine, additional, Naccache, Marie-Astrid, additional, Crombe, Pauline, additional, Bulot, Christine, additional, Rolland, Anne-Laure, additional, Blin-Zbiegiel, Elisabeth, additional, Boissinot, Mélanie, additional, Joly, Bruno, additional, Dubreuil, Anne, additional, Mathieu, Camille, additional, Pragout, David, additional, Zaffreya, Sophie, additional, Touati, Arabella, additional, Balcon, Carla, additional, Perry, Frédéric, additional, Turuban, Christelle, additional, Rapin, Sabine, additional, Pastor, Christine, additional, Cavellec, Morane, additional, Paredes Manyari, Ernesto, additional, Albane, Soria, additional, Dernivoix, Katy, additional, Trouillet, Camille, additional, Ghiringelli, Eva, additional, Pantin, Karen, additional, Garreau, Damien, additional, and Galet, Jérôme, additional
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- 2022
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14. Tenofovir DF/emtricitabine and efavirenz combination therapy for HIV infection in patients treated for tuberculosis: the ANRS 129 BKVIR trial
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Lortholary, Olivier, Roussillon, Caroline, Boucherie, Céline, Padoin, Christophe, Chaix, Marie-Laure, Breton, Guillaume, Rami, Agathe, Veziris, Nicolas, Patey, Olivier, Caumes, Eric, May, Thierry, Molina, Jean-Michel, Robert, Jérome, Tod, Michel, Fagard, Catherine, Chêne, Geneviève, Aumaître, H., Borsato, F., Malet, M., Médus, M., Moreau, L., Neuville, S., Saada, M., Abgrall, S., Ahoudji, D., Balmard, L., Bentata, M., Bouchaud, O., Boudribila, A., Cailhol, J., Dhote, R., Djebbar, R., Gros, H., Honoré, P., Huynh, T., Krivitzky, A., Mansouri, R., Pizzocolo, C., Rouges, F., Viot, E., Amar, B., Bantsimba, J., Dellion, S., Patey, O., Richier, L., Dupon, M., Dutronc, H., Neau, D., Ragnaud, J. M., Raymond, I., Boucly, S., Gailhoustet, L., Lortholary, O., Maignan, A., Touam, F., Viard, J. P., Bergmann, J. F., Boulanger, E., Delcey, V., Diemer, M., Durel, A., Jouade, F., Parrinello, M., Rami, A., Sellier, P., Brazille, P., Leclerc, C., Welker, Y., Bernard, L., Berthé, H., Perronne, C., Salomon, J., de Truchis, P., Bolliot, C., Couzigou, C., Derradji, O., Escaut, L., Teicher, E., Vittecoq, D., Chakvetadze, C., Fontaine, C., LʼYavanc, T., Maresca, A., Pialoux, G., Slama, L., Tuna, L., Bornarel, D., Boué, F., Chassaing, A., Chaiba-Berroukeche, L., Chambrin, V., Delavalle, A. M., Galanaud, P., Levy, A., Pignon, C., Bonnet, D., Ecobichon, J. L., Fournier, I., Fraquiero, G., Gerbe, J., Gervais, A., Guiyedi, V., Iordache, L., Joly, V., Klutse, P., Laurichesse, J. J., Leport, C., Onanga, M., Pahlaval, G., Phung, B. C., Ralaimazava, P., Yeni, P., Almasi, F., Basler, M., Benammar, N., Brunes, A., Guérin, C., Guillevin, L., Meddour, R., Salmon, D., Spiridon, G., Tahi, T., Bloch, M., Ferreira, C., Mahe, I., Manceron, V., Minozzi, C., Mortier, E., Simonpoli, A. M., Vinceneux, P., Zeng Ai, F., Chesnel, C., Dominguez, S., Jouve, P., Lascaux-Cametz, A. S., Lelièvre, J. D., Levy, Y., Melica, G., Sobel, A., Bentaleb, N., Blondin-Diop, A., Bonmarchand, M., Bossi, P., Brancon, C., Breton, G., Bricaire, F., Caby, F., Canestri, A., Clavel, C., Edeb, N., Herson, S., Iguertsira, M., Katlama, C., Kouadio, H., Lagarde, P., Lopez, J. L., Marguet, F., Martinez, V., Remidi, H., Simon, A., Souchon, J. F., Valantin, M. A., Bollens, D., Girard, P. M., Lagneau, J. L., Lefebvre, B., Mouchotte, R., Ouazene, Z., Sebire, M., Theveny-Christiany, A., Valin, N., Bourgarit, A., de Castro, N., Delgado, J., Ferret, S., Lascoux-Combe, C., Molina, J. M., Parlier, S., Pavie, J., Pintado, C., Ponscarme, D., Rachline, A., Sereni, D., Taulera, O., de Verdiere, C., Vincent, F., Bernard, N., Bonarek, M., Bonnet, F., Delaune, J., Lacoste, D., Louis, I., Malvy, D., Mercier, P., Morlat, P., Pertusa, M. C., Schottey, M., Chanteloube, N., Eden, A., Le Moing, V., Makilson, A., de Boever, C. Merle, Reynes, J., Turrière, C., Tramoni, C., Vidal, M., Anavena, C., Billaud, E., Biron, C., Bonnet, B., Bouchez, J., Boutoille, D., Brosseau, D., Brunct, C., Colas, M., Feuillebois, N., Hüe, H., Launay, E., le Houssine, P. Morineau, Raffi, F., Reliquet, V., Cua, E., Dellamonica, P., Durant, J., Rahelinirina, V., Arvieux, C., Chapplain, J. M., Fily, F., Labbay, E., Michelet, C., Morin, F., Peaucelle, C., Revest, M., Ratajczak, M., Souala, F., Tattevin, P., Thomas, R., Alvarez, M., Balsarin, F., Bonnet, E., Busato, F., Cuzin, L., Marche, D., Marchou, B., Massip, P., Obadia, M., Porte, L., Aissi, E., Ajana, F., Alcaraz, I., Baclet, V., Dubus, S., Gérard, Y., Guerroumi, H., Huleux, T., Lahouste, A., Marien, M. C., Melliez, H., Mouton, Y., Pennel, M. P., Valette, M., Viget, N., Yazdanpanah, Y., Bevilacqua, S., Boyer, L., Lecompte, T., Letranchant, L., May, T., Rabaud, C., Thomas, L., Vancon, R., Wassoumbou, S., Abboud, P., Borsa-Lebas, F., Caron, F., Debab, Y., Etienne, M., Faucon, M., Gueit, I., Brouqui, P., Mokhtari, S., Moreau, J., Schlojsers, M., Vandergheynst, E., Chousterman, M., Delacroix-Szmania, I., El Harrar, B., Garrait, V., Joannes, S., Luquet-Besson, I., Mouchet, M., Richier, L., Stevens, A. Blase, Dupont, C., Maresca, A. Freire, Greffe, S., Hanslik, T., Landi, B., Leporrier, J., Rouveix, E., Toth, K., El Mansouf, L., Khuong-Josses, M. A., Méchali, D., Le Besnerais, J. Phalip, Taverne, B., Barclay, F., Fain, O., Flexor, G., Stirnemann, J., Tassi, S., Levast, M., Rogeaux, O., Raffenot, D., Tous, J., Lortholary, O., Bouchaud, O., Chaix, M. L., Chêne, G., Couffin-Cadiergues, S., Dupon, M., Fagard, C., Joly, V., Launay, O., Molina, J. M., Robert, J., Roussillon, C., Rouzioux, C., Tod, M., Yazdanpanah, Y., Lortholary, O., Breton, G., Caumes, E., May, T., Roussillon, C., Veziris, N., Badets, M., Boucherie, C., Fagard, C., Chêne, G., Roussillon, C., Terras, N., Guérin, C., Altare, F., Bourgarit, A., Carcelain, G., Trylesinski, A., Aubron-Olivier, C., Nguyen, T., and Bennai, Y.
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- 2016
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15. Biomarkers of CD4+ T-cell activation as risk factors for tuberculosis-associated immune reconstitution inflammatory syndrome
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Chakrabarti, Lisa A., Boucherie, Céline, Bugault, Florence, Cumont, Marie-Christine, Roussillon, Caroline, Breton, Guillaume, Patey, Olivier, Chêne, Geneviève, Richert, Laura, and Lortholary, Olivier
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- 2014
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16. Causes of death among HIV-infected patients in France in 2010 (national survey): trends since 2000
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Morlat, Philippe, Roussillon, Caroline, Henard, Sandrine, Salmon, Dominique, Bonnet, Fabrice, Cacoub, Patrice, Georget, Aurore, Aouba, Albertine, Rosenthal, Eric, May, Thierry, Chauveau, Marie, Diallo, Bilghissa, Costagliola, Dominique, and Chene, Geneviève
- Published
- 2014
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17. Tranexamic Acid for the Prevention of Blood Loss after Cesarean Delivery
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Sentilhes, Loïc, primary, Sénat, Marie V., additional, Le Lous, Maëla, additional, Winer, Norbert, additional, Rozenberg, Patrick, additional, Kayem, Gilles, additional, Verspyck, Eric, additional, Fuchs, Florent, additional, Azria, Elie, additional, Gallot, Denis, additional, Korb, Diane, additional, Desbrière, Raoul, additional, Le Ray, Camille, additional, Chauleur, Céline, additional, de Marcillac, Fanny, additional, Perrotin, Franck, additional, Parant, Olivier, additional, Salomon, Laurent J., additional, Gauchotte, Emilie, additional, Bretelle, Florence, additional, Sananès, Nicolas, additional, Bohec, Caroline, additional, Mottet, Nicolas, additional, Legendre, Guillaume, additional, Letouzey, Vincent, additional, Haddad, Bassam, additional, Vardon, Delphine, additional, Madar, Hugo, additional, Mattuizzi, Aurélien, additional, Daniel, Valérie, additional, Regueme, Sophie, additional, Roussillon, Caroline, additional, Benard, Antoine, additional, Georget, Aurore, additional, Darsonval, Astrid, additional, and Deneux-Tharaux, Catherine, additional
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- 2021
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18. Continuous versus intermittent treatment strategies during primary HIV-1 infection: the randomized ANRS INTERPRIM Trial
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Goujard, Cécile, Emilie, Dominique, Roussillon, Caroline, Godot, Véronique, Rouzioux, Christine, Venet, Alain, Colin, Céline, Pialoux, Gilles, Girard, Pierre-Marie, Boilet, Valérie, Chaix, Marie-Laure, Galanaud, Pierre, and Chene, Geneviève
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- 2012
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19. Compliance of French academic clinical trials with the Clinical Trial Facilitation and Coordination Group recommendations on contraception and pregnancy testing requirements
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Crepin, Sabrina, primary, Chiffoleau, Anne, additional, Gavard, Marylaure, additional, Olivier-Abbal, Pascale, additional, Roussillon, Caroline, additional, Ruault, Sophie, additional, Muller, Charlotte, additional, Peyro-Saint-Paul, Laure, additional, Ouk, Thavarak, additional, Franceschi, Marie-Paule, additional, Mouchel, Catherine, additional, Duranton, Sophie, additional, Petitpain, Nadine, additional, and Coubret-Dumas, Anne, additional
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- 2020
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20. Incidence of serious adverse drug reactions in general practice: A prospective study
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Lacoste-Roussillon, Caroline, Pouyanne, Pierre, Haramburu, Françoise, Miremont, Ghada, and Bégaud, Bernard
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- 2001
21. Detection of drug safety signals from clinical trials data: Role of SUSARs
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Perez, Christelle, primary, Olivier, Pascale, additional, Lortal, Barbara, additional, Duranton, Sophie, additional, Montastruc, Jean-Louis, additional, Colin, Anne-Laurène, additional, Toulza, Emilie, additional, Becker, Madlyne, additional, Hamy, Laura, additional, Crepin, Sabrina, additional, Roussillon, Caroline, additional, Gimbert, Anne, additional, Petitpain, Nadine, additional, and Salvo, Francesco, additional
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- 2018
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22. Efficacy and safety of varenicline for smoking cessation in people living with HIV in France (ANRS 144 Inter-ACTIV): a randomised controlled phase 3 clinical trial
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Mercié, Patrick, primary, Arsandaux, Julie, additional, Katlama, Christine, additional, Ferret, Samuel, additional, Beuscart, Aurélie, additional, Spadone, Christian, additional, Duvivier, Claudine, additional, Reynes, Jacques, additional, Wirth, Nathalie, additional, Moinot, Laetitia, additional, Bénard, Antoine, additional, Zucman, David, additional, Duval, Xavier, additional, Molina, Jean-Michel, additional, Spire, Bruno, additional, Fagard, Catherine, additional, Chêne, Geneviève, additional, Allaguy-Salachy, Hélène, additional, Aubin, Henri-Jean, additional, Bernard-Henry, Claudine, additional, Beuscart, Claude, additional, Borgne, Anne, additional, Bouchaud, Olivier, additional, Brahmy, Charles, additional, Breilh, Dominique, additional, Cabié, André, additional, Cateland, Claude, additional, Cheret, Antoine, additional, Couffin-Cadiergues, Sandrine, additional, Dautzenberg, Marie-Dominique, additional, Dellamonica, Pierre, additional, Denis-Kandel, Pascale, additional, Denis-Vatant, Christine, additional, Detilleux, Michel, additional, Dupon, Michel, additional, El Harrar, Brigitte, additional, Fagnen Sylvaire, Marie Christine, additional, Guillermet, Simone, additional, Jacomet, Christine, additional, Jeantils, Vincent, additional, Korzek, Marek, additional, Lazaro, Estibaliz, additional, Le Maitre, Béatrice, additional, Lucht, Frédéric, additional, Maquet, Marianne, additional, Mathieu, Audrey, additional, May, Thierry, additional, Mercié, Patrick, additional, Merigeaud, Sonia, additional, Morlat, Philippe, additional, Naqvi, Alissa, additional, Neau, Didier, additional, Perriot, Jean, additional, Pierre-François, Sandrine, additional, Poizot-Martin, Isabelle, additional, Quoix, Elisabeth, additional, Rebillard, Matthieu, additional, Roussillon, Caroline, additional, Rosenthal, Eric, additional, Sainte-Marie, Thierry, additional, Salmon-Céron, Dominique, additional, Schneider, Luminita, additional, Simon, Anne, additional, Soussi, Malika, additional, Sotto, Albert, additional, Taburet, Anne-Marie, additional, Teicher, Elina, additional, Termote, Monique, additional, Trosini-Desert, Valery, additional, Verdon, Renaud, additional, Viard, Jean-Paul, additional, Vittecoq, Daniel, additional, Vray, Muriel, additional, and Youssi, David, additional
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- 2018
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23. Le projet MRi-Share : IRM d’une cohorte de 2000 étudiants. État d’avancement et résultats préliminaires
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Mazoyer, Bernard, primary, Mellet, Emmanuel, additional, Tzourio-Mazoyer, Nathalie, additional, Perchey, Guy, additional, Hervé, Pierre-Yves, additional, Crivello, Fabrice, additional, Joliot, Marc, additional, Petit, Laurent, additional, Knafo, Louise, additional, Roussillon, Caroline, additional, Capelli, Aurore, additional, Tourdias, Thomas, additional, Zago, Laure, additional, Debette, Stéphanie, additional, and Tzourio, Christophe, additional
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- 2017
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24. Cancer-Related Causes of Death among HIV-Infected Patients in France in 2010: Evolution since 2000
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Vandenhende, Marie-Anne, Roussillon, Caroline, Henard, Sandrine, Morlat, Philippe, Oksenhendler, Eric, Aumaitre, Hugues, Georget, Aurore, May, Thierry, Rosenthal, Eric, Salmon, Dominique, Cacoub, Patrice, Costagliola, Dominique, Chêne, Geneviève, Bonnet, Fabrice, HAL UPMC, Gestionnaire, Epidémiologie et Biostatistique [Bordeaux], Université Bordeaux Segalen - Bordeaux 2-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de médecine interne et maladies infectieuses [Bordeaux], CHU Bordeaux [Bordeaux]-Groupe hospitalier Saint-André, Service des Maladies Infectieuses et Tropicales [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service d'Immunopathologie [Hôpital Saint-Louis, Paris], Université Paris Diderot - Paris 7 (UPD7)-Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service des maladies infectieuses CHU Perpignan, Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Service de médecine interne CHU de l'Archet, Université Paris Descartes - Paris 5 (UPD5), Unité de pathologie infectieuse CHU Cochin, Service de médecine interne [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Université Pierre et Marie Curie - Paris 6 (UPMC), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Nice Sophia Antipolis (... - 2019) (UNS), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Bordeaux Segalen - Bordeaux 2-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Université Paris Diderot - Paris 7 ( UPD7 ) -CHU Saint Louis [APHP], Université Nice Sophia Antipolis ( UNS ), Université Côte d'Azur ( UCA ), Université Paris Descartes - Paris 5 ( UPD5 ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Pitié-Salpêtrière [APHP], Université Pierre et Marie Curie - Paris 6 ( UPMC ), Institut Pierre Louis d'Epidémiologie et de Santé Publique ( iPLESP ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ), CHU Pitié-Salpêtrière [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
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Adult ,Male ,HIV ,HIV Infections ,[SDV.CAN]Life Sciences [q-bio]/Cancer ,Middle Aged ,[ SDV.CAN ] Life Sciences [q-bio]/Cancer ,[ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,[SDV.CAN] Life Sciences [q-bio]/Cancer ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Cause of Death ,Neoplasms ,[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Humans ,Female ,France ,Research Article - Abstract
the ARNS EN20 Mortalité 2010 study group; International audience; ObjectivesThe current study aimed at describing the distribution and characteristics of malignancy related deaths in human immunodeficiency virus (HIV) infected patients in 2010 and at comparing them to those obtained in 2000 and 2005.MethodsData were obtained from three national surveys conducted in France in 2010, 2005 and 2000. The underlying cause of death was documented using a standardized questionnaire fulfilled in French hospital wards involved in the management of HIV infection.ResultsAmong the 728 deaths reported in 2010, 262 were cancer-related (36%). After a significant increase from 28% in 2000 to 33% in 2005 and 36% in 2010, cancers represent the leading cause of mortality in HIV infected patients. The proportion of deaths attributed to non-AIDS/non-hepatitis-related cancers significantly increased from 2000 to 2010 (11% of the deaths in 2000, 17% in 2005 and 22% in 2010, p
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- 2015
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25. Tranexamic Acid for the Prevention of Blood Loss After Cesarean Delivery
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Sentilhes, Loic, Sénat, Marie V., Le Lous, Maela, Winer, Norbert, Rozenberg, Patrick, Kayem, Gilles, Verspyck, Eric, Fuchs, Florent, Azria, Elie, Gallot, Denis, Korb, Diane, Desbrière, Raoul, Le Ray, Camille, Chauleur, Celine, de Marcillac, Fanny, Perrotin, Franck, Parant, Olivier, Salomon, Laurent J., Gauchotte, Emilie, Bretelle, Florence, Sananès, Nicolas, Bohec, Caroline, Mottet, Nicolas, Legendre, Guillaume, Letouzey, Vincent, Haddad, Bassam, Vardon, Delphine, Madar, Hugo, Mattuizzi, Aurelien, Daniel, Valerie, Regueme, Sophie, Roussillon, Caroline, Benard, Antoine, Georget, Aurore, Darsonval, Astrid, and Deneux-Tharaux, Catherine
- Abstract
(Abstracted from N Engl J Med2021;384:1623–1634)Uterotonic agents are recommended to prevent postpartum hemorrhage (PPH). Tranexamic acid (TXA) has emerged as another medical approach to prevent blood loss after delivery.
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- 2021
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26. Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial).
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Duvignaud, Alexandre, Lhomme, Edouard, Pistone, Thierry, Onaisi, Racha, Sitta, Rémi, Journot, Valérie, Nguyen, Duc, Peiffer-Smadja, Nathan, Crémer, Antoine, Bouchet, Stéphane, Darnaud, Thomas, Poitrenaud, Delphine, Piroth, Lionel, Binquet, Christine, Michel, Jean-François, Lefèvre, Benjamin, Lebeaux, David, Lebel, Josselin, Dupouy, Julie, and Roussillon, Caroline
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OLD age homes ,COVID-19 ,INVESTIGATIONAL therapies ,CHRONIC hepatitis B ,GLUCOSE-6-phosphate dehydrogenase deficiency ,COVID-19 pandemic ,HEMODIALYSIS facilities ,MEDICAL offices - Abstract
Objectives: To assess the efficacy of several repurposed drugs to prevent hospitalisation or death in patients aged 65 or more with recent symptomatic SARS-CoV-2 infection (COVID-19) and no criteria for hospitalisation.Trial Design: Phase III, multi-arm (5) and multi-stage (MAMS), randomized, open-label controlled superiority trial. Participants will be randomly allocated 1:1:1:1:1 to the following strategies: Arm 1: Control arm Arms 2 to 5: Experimental treatment arms Planned interim analyses will be conducted at regular intervals. Their results will be reviewed by an Independent Data and Safety Monitoring Board. Experimental arms may be terminated for futility, efficacy or toxicity before the end of the trial. New experimental arms may be added if new evidence suggests that other treatments should be tested. A feasibility and acceptability substudy as well as an immunological substudy will be conducted alongside the trial.Participants: Inclusion criteria are: 65-year-old or more; Positive test for SARS-CoV-2 on a nasopharyngeal swab; Symptoms onset within 3 days before diagnosis; No hospitalisation criteria; Signed informed consent; Health insurance. Exclusion criteria are: Inability to make an informed decision to participate (e.g.: dementia, guardianship); Rockwood Clinical Frailty Scale ≥7; Long QT syndrome; QTc interval > 500 ms; Heart rate <50/min; Kalaemia >5.5 mmol/L or <3.5 mmol/L; Ongoing treatment with piperaquine, halofantrine, dasatinib, nilotinib, hydroxyzine, domperidone, citalopram, escitalopram, potent inhibitors or inducers of cytochrome P450 CYP3A4 isoenzyme, repaglinide, azathioprine, 6-mercaptopurine, theophylline, pyrazinamide, warfarin; Known hypersensitivity to any of the trial drugs or to chloroquine and other 4-aminoquinolines, amodiaquine, mefloquine, glafenine, floctafenine, antrafenine, ARB; Hepatic porphyria; Liver failure (Child-Pugh stage ≥B); Stage 4 or 5 chronic kidney disease (GFR <30 mL/min/1.73 m²); Dialysis; Hypersentivity to lactose; Lactase deficiency; Abnormalities in galactose metabolism; Malabsorption syndrome; Glucose-6-phosphate dehydrogenase deficiency; Symptomatic hyperuricemia; Ileus; Colitis; Enterocolitis; Chronic hepatitis B virus disease. The trial is being conducted in France in the Bordeaux, Corse, Dijon, Nancy, Paris and Toulouse areas as well as in the Grand Duchy of Luxembourg. Participants are recruited either at home, nursing homes, general practices, primary care centres or hospital outpatient consultations.Intervention and Comparator: The four experimental treatments planned in protocol version 1.2 (April 8th, 2020) are: (1) Hydroxychloroquine 200 mg, 2 tablets BID on day 0, 2 tablets QD from day 1 to 9; (2) Imatinib 400 mg, 1 tablet QD from day 0 to 9; (3) Favipiravir 200 mg, 12 tablets BID on day 0, 6 tablets BID from day 1 to 9; (4) Telmisartan 20 mg, 1 tablet QD from day 0 to 9. The comparator is a complex of vitamins and trace elements (AZINC Forme et Vitalité®), 1 capsule BID for 10 days, for which there is no reason to believe that they are active on the virus. In protocol version 1.2 (April 8th, 2020): People in the control arm will receive a combination of vitamins and trace elements; people in the experimental arms will receive hydroxychloroquine, or favipiravir, or imatinib, or telmisartan.Main Outcome: The primary outcome is the proportion of participants with an incidence of hospitalisation and/or death between inclusion and day 14 in each arm.Randomisation: Participants are randomized in a 1:1:1:1:1 ratio to each arm using a web-based randomisation tool. Participants not treated with an ARB or ACEI prior to enrolment are randomized to receive the comparator or one of the four experimental drugs. Participants already treated with an ARB or ACEI are randomized to receive the comparator or one of the experimental drugs except telmisartan (i.e.: hydroxychloroquine, imatinib, or favipiravir). Randomisation is stratified on ACEI or ARBs treatment at inclusion and on the type of residence (personal home vs. nursing home).Blinding (masking): This is an open-label trial. Participants, caregivers, investigators and statisticians are not blinded to group assignment.Numbers To Be Randomised (sample Size): A total of 1057 participants will be enrolled if all arms are maintained until the final analysis and no additional arm is added. Three successive futility interim analyses are planned, when the number of participants reaches 30, 60 and 102 in the control arm. Two efficacy analyses (interim n°3 and final) will be performed successively.Trial Status: This describes the Version 1.2 (April 8th, 2020) of the COVERAGE protocol that was approved by the French regulatory authority and ethics committee. The trial was opened for enrolment on April 15th, 2020 in the Nouvelle Aquitaine region (South-West France). Given the current decline of the COVID-19 pandemic in France and its unforeseeable dynamic in the coming months, new trial sites in 5 other French regions and in Luxembourg are currently being opened. A revised version of the protocol was submitted to the regulatory authority and ethics committee on June 15th, 2020. It contains the following amendments: (i) Inclusion criteria: age ≥65 replaced by age ≥60; time since first symptoms <3 days replaced by time since first symptoms <5 days; (ii) Withdrawal of the hydroxychloroquine arm (due to external data); (iii) increase in the number of trial sites.Trial Registration: The trial was registered on Clinical Trials.gov on April 22nd, 2020 (Identifier: NCT04356495): and on EudraCT on April 10th, 2020 (Identifier: 2020-001435-27).Full Protocol: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest of expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol. The study protocol has been reported in accordance with the Standard Protocol Items: Recommendations for Clinical Interventional Trials (SPIRIT) guidelines (Additional file 2). [ABSTRACT FROM AUTHOR]- Published
- 2020
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27. Tenofovir DF/emtricitabine and efavirenz combination therapy for HIV infection in patients treated for tuberculosis: the ANRS 129 BKVIR trial
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Lortholary, Olivier, primary, Roussillon, Caroline, additional, Boucherie, Céline, additional, Padoin, Christophe, additional, Chaix, Marie-Laure, additional, Breton, Guillaume, additional, Rami, Agathe, additional, Veziris, Nicolas, additional, Patey, Olivier, additional, Caumes, Eric, additional, May, Thierry, additional, Molina, Jean-Michel, additional, Robert, Jérome, additional, Tod, Michel, additional, Fagard, Catherine, additional, and Chêne, Geneviève, additional
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- 2015
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28. Biomarkers of CD4T-cell activation as risk factors for tuberculosis-associated immune reconstitution inflammatory syndrome
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Chakrabarti, Lisa A., Boucherie, Céline, Bugault, Florence, Cumont, Marie-Christine, Roussillon, Caroline, Breton, Guillaume, Patey, Olivier, Chêne, Geneviève, Richert, Laura, and Lortholary, Olivier
- Abstract
Patients coinfected with HIV and Mycobacterium tuberculosisfrequently experience a paradoxical worsening of tuberculosis (TB) symptoms early after the initiation of combination antiretroviral therapy (cART). This immune reconstitution inflammatory syndrome (TB-IRIS) can lead to significant morbidity and needs to be distinguished from TB recurrence due to ineffective treatment. We investigated whether plasma biomarkers could predict the occurrence of TB-IRIS.
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- 2014
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29. Cancer-Related Causes of Death among HIV-Infected Patients in France in 2010: Evolution since 2000.
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Vandenhende MA, Roussillon C, Henard S, Morlat P, Oksenhendler E, Aumaitre H, Georget A, May T, Rosenthal E, Salmon D, Cacoub P, Costagliola D, Chêne G, and Bonnet F
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- Adult, Cause of Death, Female, France epidemiology, HIV isolation & purification, HIV Infections epidemiology, Humans, Male, Middle Aged, Neoplasms epidemiology, HIV Infections complications, HIV Infections mortality, Neoplasms complications, Neoplasms mortality
- Abstract
Objectives: The current study aimed at describing the distribution and characteristics of malignancy related deaths in human immunodeficiency virus (HIV) infected patients in 2010 and at comparing them to those obtained in 2000 and 2005., Methods: Data were obtained from three national surveys conducted in France in 2010, 2005 and 2000. The underlying cause of death was documented using a standardized questionnaire fulfilled in French hospital wards involved in the management of HIV infection., Results: Among the 728 deaths reported in 2010, 262 were cancer-related (36%). After a significant increase from 28% in 2000 to 33% in 2005 and 36% in 2010, cancers represent the leading cause of mortality in HIV infected patients. The proportion of deaths attributed to non-AIDS/non-hepatitis-related cancers significantly increased from 2000 to 2010 (11% of the deaths in 2000, 17% in 2005 and 22% in 2010, p<0.001), while those attributed to AIDS-defining cancers decreased during the same period (16% in 2000, 13% in 2005 and 9% in 2010, p = 0.024). Particularly, the proportion of respiratory cancers significantly increased from 5% in 2000 to 6% in 2005 and 11% in 2010 (p = 0.004). Lung cancer was the most common cancer-related cause of death in 2010 (instead of non-Hodgkin lymphoma so far) and represented the leading cause of death in people living with HIV overall., Conclusions: Cancer prevention (especially smoking cessation), screening strategies and therapeutic management need to be optimized in HIV-infected patients in order to reduce mortality, particularly in the field of respiratory cancers.
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- 2015
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