684 results on '"Rotili, Dante"'
Search Results
2. The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases
3. Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
4. SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells
5. Structure-based mechanism of riboregulation of the metabolic enzyme SHMT1
6. Molecular insights into RmcA-mediated c-di-GMP consumption: Linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa
7. The role of structural biology in the design of sirtuin activators
8. Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
9. Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation
10. Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity
11. (Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling
12. Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics
13. Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
14. Multimodal evaluation of 19F-BPA internalization in pancreatic cancer cells for boron capture and proton therapy potential applications
15. Uracil‐ and Pyridine‐Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells
16. Successes and challenges in the development of BD1-selective BET inhibitors: a patent review
17. Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors
18. Feasibility of the $\beta^-$ Radio-Guided Surgery with a Variety of Radio-Nuclides of Interest to Nuclear Medicine
19. Enhancing sensitivity of triple-negative breast cancer to DNA-damaging therapy through chemical inhibition of the m6A methyltransferase METTL3
20. Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs)
21. Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development.
22. M6A reduction relieves FUS-associated ALS granules.
23. DNA Methylation: Biological Implications and Modulation of Its Aberrant Dysregulation
24. Targeting histone acetylation/deacetylation in parasites: an update (2017–2020)
25. HDAC1-3 inhibition increases SARS-CoV-2 replication and productive infection in lung mesothelial and epithelial cells
26. BET Protein Inhibitor JQ1 Ameliorates Experimental Peritoneal Damage by Inhibition of Inflammation and Oxidative Stress
27. Identification of novel quinazoline derivatives as potent antiplasmodial agents
28. A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.
29. Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity.
30. M6A reduction relieves FUS-associated ALS granules
31. Hydroxamate-based compounds are potent inhibitors of Toxoplasma gondii HDAC biological activity
32. SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells
33. State of the art of carbonic anhydrase activators
34. Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load
35. Molecular insights into RmcA-mediated c-di-GMP consumption: linking redox potential to biofilm morphogenesis in Pseudomonas aeruginosa
36. Contributors
37. HAT inhibitors in cancer therapy
38. Mass spectrometry characterization of DOTA-Nimotuzumab conjugate as precursor of an innovative β− tracer suitable in radio-guided surgery
39. METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey
40. First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8
41. The relevance of Ki calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor
42. Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity
43. Radioguided surgery with β− radiation in pancreatic Neuroendocrine Tumors: a feasibility study
44. Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells
45. Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII.
46. Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells.
47. Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors
48. Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches
49. Supplementary Figures from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
50. Supplementary Tables from RIP1–HAT1–SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer
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