25 results on '"Rotge J. -Y."'
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2. Forgetting what you have checked: A link between working memory impairment and checking behaviors in obsessive-compulsive disorder
- Author
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Jaafari, N., Frasca, M., Rigalleau, F., Rachid, F., Gil, R., Olié, J.-P., Guehl, D., Burbaud, P., Aouizerate, B., Rotgé, J.-Y., and Vibert, N.
- Published
- 2013
- Full Text
- View/download PDF
3. Intérêt de l’électroconvulsivothérapie (ECT) chez les sujets âgés souffrant d’une pathologie démentielle : une revue de la littérature
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Quentin, S., Voyer, M., Daniel, M.-L., Rachid, F., Paillard, C., Wassouf, I., Sharov, I., Depond, B., Rotge, J.-Y., Senon, J.-L., and Jaafari, N.
- Published
- 2010
- Full Text
- View/download PDF
4. Differential role of visuospatial working memory in the propensity toward uncertainty in patients with obsessive–compulsive disorder and in healthy subjects
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Lambrecq, V., Rotge, J.-Y., Jaafari, N., Aouizerate, B., Langbour, N., Bioulac, B., Liégeois-Chauvel, C., Burbaud, P., and Guehl, D.
- Published
- 2014
5. Evolution of brain gray matter loss in Huntingtonʼs disease: a meta-analysis
- Author
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Lambrecq, V., Langbour, N., Guehl, D., Bioulac, B., Burbaud, P., and Rotge, J.-Y.
- Published
- 2013
- Full Text
- View/download PDF
6. A critical review of the contribution of eye movement recordings to the neuropsychology of obsessive compulsive disorder
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Jaafari, N., Rigalleau, F., Rachid, F., Delamillieure, P., Millet, B., Olié, J.-P., Gil, R., Rotge, J.-Y., and Vibert, N.
- Published
- 2011
- Full Text
- View/download PDF
7. A challenging task for assessment of checking behaviors in obsessive–compulsive disorder
- Author
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Rotge, J. Y., Clair, A. H., Jaafari, N., Hantouche, E. G., Pelissolo, A., Goillandeau, M., Pochon, J. B., Guehl, D., Bioulac, B., Burbaud, P., Tignol, J., Mallet, L., and Aouizerate, B.
- Published
- 2008
8. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
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Brown, P. Zhou, Y. Tan, A.-C. El-Esawi, M.A. Liehr, T. Blanck, O. Gladue, D.P. Almeida, G.M.F. Cernava, T. Sorzano, C.O. Yeung, A.W.K. Engel, M.S. Chandrasekaran, A.R. Muth, T. Staege, M.S. Daulatabad, S.V. Widera, D. Zhang, J. Meule, A. Honjo, K. Pourret, O. Yin, C.-C. Zhang, Z. Cascella, M. Flegel, W.A. Goodyear, C.S. van Raaij, M.J. Bukowy-Bieryllo, Z. Campana, L.G. Kurniawan, N.A. Lalaouna, D. Hüttner, F.J. Ammerman, B.A. Ehret, F. Cobine, P.A. Tan, E.-C. Han, H. Xia, W. McCrum, C. Dings, R.P.M. Marinello, F. Nilsson, H. Nixon, B. Voskarides, K. Yang, L. Costa, V.D. Bengtsson-Palme, J. Bradshaw, W. Grimm, D.G. Kumar, N. Martis, E. Prieto, D. Sabnis, S.C. Amer, S.E.D.R. Liew, A.W.C. Perco, P. Rahimi, F. Riva, G. Zhang, C. Devkota, H.P. Ogami, K. Basharat, Z. Fierz, W. Siebers, R. Tan, K.H. Boehme, K.A. Brenneisen, P. Brown, J.A.L. Dalrymple, B.P. Harvey, D.J. Ng, G. Werten, S. Bleackley, M. Dai, Z. Dhariwal, R. Gelfer, Y. Hartmann, M.D. Miotla, P. Tamaian, R. Govender, P. Gurney-Champion, O.J. Kauppila, J.H. Zhang, X. Echeverría, N. Subhash, S. Sallmon, H. Tofani, M. Bae, T. Bosch, O. Cuív, P.O. Danchin, A. Diouf, B. Eerola, T. Evangelou, E. Filipp, F. Klump, H. Kurgan, L. Smith, S.S. Terrier, O. Tuttle, N. Ascher, D.B. Janga, S.C. Schulte, L.N. Becker, D. Browngardt, C. Bush, S.J. Gaullier, G. Ide, K. Meseko, C. Werner, G.D.A. Zaucha, J. Al-Farha, A.A. Greenwald, N.F. Popoola, S.I. Rahman, S. Xu, J. Yang, S.Y. Hiroi, N. Alper, O.M. Baker, C.I. Bitzer, M. Chacko, G. Debrabant, B. Dixon, R. Forano, E. Gilliham, M. Kelly, S. Klempnauer, K.-H. Lidbury, B.A. Lin, M.Z. Lynch, I. Ma, W. Maibach, E.W. Mather, D.E. Nandakumar, K.S. Ohgami, R.S. Parchi, P. Tressoldi, P. Xue, Y. Armitage, C. Barraud, P. Chatzitheochari, S. Coelho, L.P. Diao, J. Doxey, A.C. Gobet, A. Hu, P. Kaiser, S. Mitchell, K.M. Salama, M.F. Shabalin, I.G. Song, H. Stevanovic, D. Yadollahpour, A. Zeng, E. Zinke, K. Alimba, C.G. Beyene, T.J. Cao, Z. Chan, S.S. Gatchell, M. Kleppe, A. Piotrowski, M. Torga, G. Woldesemayat, A.A. Cosacak, M.I. Haston, S. Ross, S.A. Williams, R. Wong, A. Abramowitz, M.K. Effiong, A. Lee, S. Abid, M.B. Agarabi, C. Alaux, C. Albrecht, D.R. Atkins, G.J. Beck, C.R. Bonvin, A.M.J.J. Bourke, E. Brand, T. Braun, R.J. Bull, J.A. Cardoso, P. Carter, D. Delahay, R.M. Ducommun, B. Duijf, P.H.G. Epp, T. Eskelinen, E.-L. Fallah, M. Farber, D.B. Fernandez-Triana, J. Feyerabend, F. Florio, T. Friebe, M. Furuta, S. Gabrielsen, M. Gruber, J. Grybos, M. Han, Q. Heinrich, M. Helanterä, H. Huber, M. Jeltsch, A. Jiang, F. Josse, C. Jurman, G. Kamiya, H. de Keersmaecker, K. Kristiansson, E. de Leeuw, F.-E. Li, J. Liang, S. Lopez-Escamez, J.A. Lopez-Ruiz, F.J. Marchbank, K.J. Marschalek, R. Martín, C.S. Miele, A.E. Montagutelli, X. Morcillo, E. Nicoletti, R. Niehof, M. O'Toole, R. Ohtomo, T. Oster, H. Palma, J.-A. Paterson, R. Peifer, M. Portilla, M. Portillo, M.C. Pritchard, A.L. Pusch, S. Raghava, G.P.S. Roberts, N.J. Ross, K. Schuele, B. Sergeant, K. Shen, J. Stella, A. Sukocheva, O. Uversky, V.N. Vanneste, S. Villet, M.H. Viveiros, M. Vorholt, J.A. Weinstock, C. Yamato, M. Zabetakis, I. Zhao, X. Ziegler, A. Aizat, W.M. Atlas, L. Bridges, K.M. Chakraborty, S. Deschodt, M. Domingues, H.S. Esfahlani, S.S. Falk, S. Guisado, J.L. Kane, N.C. Kueberuwa, G. Lau, C.L. Liang, D. Liu, E. Luu, A.M. Ma, C. Ma, L. Moyer, R. Norris, A.D. Panthee, S. Parsons, J.R. Peng, Y. Pinto, I.M. Reschke, C.R. Sillanpää, E. Stewart, C.J. Uhle, F. Yang, H. Zhou, K. Zhu, S. Ashry, M. Bergsland, N. Berthold, M. Chen, C.-E. Colella, V. Cuypers, M. Eskew, E.A. Fan, X. Gajda, M. Gonzálezlez-Prendes, R. Goodin, A. Graham, E.B. Groen, E.J.N. Gutiérrez-Sacristán, A. Habes, M. Heffler, E. Higginbottom, D.B. Janzen, T. Jayaraman, J. Jibb, L.A. Jongen, S. Kinyanjui, T. Koleva-Kolarova, R.G. Li, Z. Liu, Y.-P. Lund, B.A. Lussier, A.A. Ma, L. Mier, P. Moore, M.D. Nagler, K. Orme, M.W. Pearson, J.A. Prajapati, A.S. Saito, Y. Tröder, S.E. Uchendu, F. Verloh, N. Voutchkova, D.D. Abu-Zaid, A. Bakkach, J. Baumert, P. Dono, M. Hanson, J. Herbelet, S. Hobbs, E. Kulkarni, A. Kumar, N. Liu, S. Loft, N.D. Reddan, T. Senghore, T. Vindin, H. Xu, H. Bannon, R. Chen, B. Cheung, J.T.K. Cooper, J. Esnakula, A.K. Feghali, K.A. Ghelardi, E. Gnasso, A. Horbar, J. Lai, H.M. Li, J. Ma, L. Ma, R. Pan, Z. Peres, M.A. Pranata, R. Seow, E. Sydes, M. Testoni, I. Westermair, A.L. Yang, Y. Afnan, M. Albiol, J. Albuquerque, L.G. Amir, S. Amiya, E. Amorim, R.M. An, Q. Andersen, S.U. Aplin, J.D. Argyropoulos, C. Asmann, Y.W. Assaeed, A.M. Atanasov, A.G. Atchison, D.A. Avery, S.V. Avillach, P. Baade, P.D. Backman, L. Badie, C. Baldi, A. Ball, E. Bardot, O. Barnett, A.G. Basner, M. Batra, J. Bazanova, O.M. Beale, A. Beddoe, T. Bell, M.L. Berezikov, E. Berners-Price, S. Bernhardt, P. Berry, E. Bessa, T.B. Billington, C. Birch, J. Blakely, R.D. Blaskovich, M.A.T. Blum, R. Boelaert, M. Bogdanos, D. Bosch, C. Bourgoin, T. Bouvard, D. Boykin, L.M. Bradley, G. Braun, D. Brownlie, J. Brühl, A. Burt, A. Butler, L.M. Byrareddy, S.N. Byrne, H.J. Cabantous, S. Calatayud, S. Candal, E. Carlson, K. Casillas, S. Castelvetro, V. Caswell, P.T. Cavalli, G. Cerovsky, V. Chagoyen, M. Chen, C.-S. Chen, D.F. Chen, H. Chen, H. Chen, J.-T. Chen, Y. Cheng, C. Cheng, J. Chinapaw, M. Chinopoulos, C. Cho, W.C.S. Chong, L. Chowdhury, D. Chwalibog, A. Ciresi, A. Cockcroft, S. Conesa, A. Cook, P.A. Cooper, D.N. Coqueret, O. Corea, E.M. Costa, A. Costa, E. Coupland, C. Crawford, S.Y. Cruz, A.D. Cui, H. Cui, Q. Culver, D.C. D'Angiulli, A. Dahms, T.E.S. Daigle, F. Dalgleish, R. Danielsen, H.E. Darras, S. Davidson, S.M. Day, D.A. Degirmenci, V. Demaison, L. Devriendt, K. Ding, J. Dogan, Y. Dong, X.C. Donner, C.F. Dressick, W. Drevon, C.A. Duan, H. Ducho, C. Dumaz, N. Dwarakanath, B.S. Ebell, M.H. Eisenhardt, S. Elkum, N. Engel, N. Erickson, T.B. Fairhead, M. Faville, M.J. Fejzo, M.S. Festa, F. Feteira, A. Flood-Page, P. Forsayeth, J. Fox, S.A. Franks, S.J. Frentiu, F.D. Frilander, M.J. Fu, X. Fujita, S. Galea, I. Galluzzi, L. Gani, F. Ganpule, A.P. García-Alix, A. Gedye, K. Giordano, M. Giunta, C. Gleeson, P.A. Goarant, C. Gong, H. Gora, D. Gough, M.J. Goyal, R. Graham, K.E. Grande-Pérez, A. Graves, P.M. Greidanus, H. Grice, D. Grunau, C. Gumulya, Y. Guo, Y. Gurevich, V.V. Gusev, O. Hacker, E. Hage, S.R. Hagen, G. Hahn, S. Haller, D.M. Hammerschmidt, S. Han, J. Han, R. Handfield, M. Hapuarachchi, H.C. Harder, T. Hardingham, J.E. Heck, M. Heers, M. Hew, K.F. Higuchi, Y. Hilaire, C.St. Hilton, R. Hodzic, E. Hone, A. Hongoh, Y. Hu, G. Huber, H.P. Hueso, L.E. Huirne, J. Hurt, L. Idborg, H. Ikeo, K. Ingley, E. Jakeman, P.M. Jensen, A. Jia, H. Jia, H. Jia, S. Jiang, J. Jiang, X. Jin, Y. Jo, D. Johnson, A.M. Johnston, M. Jonscher, K.R. Jorens, P.G. Jorgensen, J.O.L. Joubert, J.W. Jung, S.-H. Junior, A.M. Kahan, T. Kamboj, S.K. Kang, Y.-K. Karamanos, Y. Karp, N.A. Kelly, R. Kenna, R. Kennedy, J. Kersten, B. Khalaf, R.A. Khalid, J.M. Khatlani, T. Khider, T. Kijanka, G.S. King, S.R.B. Kluz, T. Knox, P. Kobayashi, T. Koch, K.-W. Kohonen-Corish, M.R.J. Kong, X. Konkle-Parker, D. Korpela, K.M. Kostrikis, L.G. Kraiczy, P. Kratz, H. Krause, G. Krebsbach, P.H. Kristensen, S.R. Kumari, P. Kunimatsu, A. Kurdak, H. Kwon, Y.D. Lachat, C. Lagisz, M. Laky, B. Lammerding, J. Lange, M. Larrosa, M. Laslett, A.L. Laverman, G.D. Leclair, E.E. Lee, K.-W. Lee, M.-Y. Lee, M.-S. Li, G. Li, J. Lieb, K. Lim, Y.Y. Lindsey, M.L. Line, P.-D. Liu, D. Liu, F. Liu, H. Liu, H. Lloyd, V.K. Lo, T.-W. Locci, E. Loidl, J. Lorenzen, J. Lorkowski, S. Lovell, N.H. Lu, H. Lu, W. Lu, Z. Luengo, G.S. Lundh, L.-G. Lysy, P.A. Mabb, A. Mack, H.G. Mackey, D.A. Mahdavi, S.R. Maher, P. Maher, T. Maity, S.N. Malgrange, B. Mamoulakis, C. Mangoni, A.A. Manke, T. Manstead, A.S.R. Mantalaris, A. Marsal, J. Marschall, H.-U. Martin, F.L. Martinez-Raga, J. Martinez-Salas, E. Mathieu, D. Matsui, Y. Maza, E. McCutcheon, J.E. McKay, G.J. McMillan, B. McMillan, N. Meads, C. Medina, L. Merrick, B.A. Metzger, D.W. Meunier, F.A. Michaelis, M. Micheau, O. Mihara, H. Mintz, E.M. Mizukami, T. Moalic, Y. Mohapatra, D.P. Monteiro, A. Montes, M. Moran, J.V. Morozov, S.Y. Mort, M. Murai, N. Murphy, D.J. Murphy, S.K. Murray, S.A. Naganawa, S. Nammi, S. Nasios, G. Natoli, R.M. Nguyen, F. Nicol, C. van Nieuwerburgh, F. Nilsen, E.B. Nobile, C.J. O'Mahony, M. Ohlsson, S. Olatunbosun, O. Olofsson, P. Ortiz, A. Ostrikov, K. Otto, S. Outeiro, T.F. Ouyang, S. Paganoni, S. Page, A. Palm, C. Paradies, Y. Parsons, M.H. Parsons, N. Pascal, P. Paul, E. Peckham, M. Pedemonte, N. Pellizzon, M.A. Petrelli, M. Pichugin, A. Pinto, C.J.C. Plevris, J.N. Pollesello, P. Polz, M. Ponti, G. Porcelli, P. Prince, M. Quinn, G.P. Quinn, T.J. Ramula, S. Rappsilber, J. Rehfeldt, F. Reiling, J.H. Remacle, C. Rezaei, M. Riddick, E.W. Ritter, U. Roach, N.W. Roberts, D.D. Robles, G. Rodrigues, T. Rodriguez, C. Roislien, J. Roobol, M.J. Rowe, A. Ruepp, A. van Ruitenbeek, J. Rust, P. Saad, S. Sack, G.H. Santos, M. Saudemont, A. Sava, G. Schrading, S. Schramm, A. Schreiber, M. Schuler, S. Schymkowitz, J. Sczyrba, A. Seib, K.L. Shi, H.-P. Shimada, T. Shin, J.-S. Shortt, C. Silveyra, P. Skinner, D. Small, I. Smeets, P.A.M. So, P.-W. Solano, F. Sonenshine, D.E. Song, J. Southall, T. Speakman, J.R. Srinivasan, M.V. Stabile, L.P. Stasiak, A. Steadman, K.J. Stein, N. Stephens, A.W. Stewart, D.I. Stine, K. Storlazzi, C. Stoynova, N.V. Strzalka, W. Suarez, O.M. Sultana, T. Sumant, A.V. Summers, M.J. Sun, G. Tacon, P. Tanaka, K. Tang, H. Tanino, Y. Targett-Adams, P. Tayebi, M. Tayyem, R. Tebbe, C.C. Telfer, E.E. Tempel, W. Teodorczyk-Injeyan, J.A. Thijs, G. Thorne, S. Thrift, A.G. Tiffon, C. Tinnefeld, P. Tjahjono, D.H. Tolle, F. Toth, E. Del Tredici, A.L. Tsapas, A. Tsirigotis, K. Turak, A. Tzotzos, G. Udo, E.E. Utsumi, T. Vaidyanathan, S. Vaillant, M. Valsesia, A. Vandenbroucke, R.E. Veiga, F.H. Vendrell, M. Vesk, P.A. Vickers, P. Victor, V.M. Villemur, R. Vohl, M.-C. Voolstra, C.R. Vuillemin, A. Wakelin, S. Waldron, L. Walsh, L.J. Wang, A.Y. Wang, F. Wang, Y. Watanabe, Y. Weigert, A. Wen, J.-C. Wham, C. White, E.P. Wiener, J. Wilharm, G. Wilkinson, S. Willmann, R. Wilson, C. Wirth, B. Wojan, T.R. Wolff, M. Wong, B.M. Wu, T.-W. Wuerbel, H. Xiao, X. Xu, D. Xu, J.W. Xu, J. Xue, B. Yalcin, S. Yan, H. Yang, E.-C. Yang, S. Yang, W. Ye, Y. Ye, Z.-Q. Yli-Kauhaluoma, J. Yoneyama, H. Yu, Y. Yuan, G.-C. Yuh, C.-H. Zaccolo, M. Zeng, C. Zevnik, B. Zhang, C. Zhang, L. Zhang, Y. Zhang, Y. Zhang, Z. Zhang, Z.-Y. Zhao, Y. Zhou, M. Zuberbier, T. Aanei, C.M. Ahmad, R. Al-Lawama, M. Alanio, A. Allardyce, J. Alonso-Caneiro, D. Atack, J.M. Baier, D. Bansal, A. Benezeth, Y. Berbesque, C. Berrevoet, F. Biedermann, P.H.W. Bijleveld, E. Bittner, F. Blombach, F. van den Bos, W. Boudreau, S.A. Bramoweth, A.D. Braubach, O. Cai, Y. Campbell, M. Cao, Z. Catry, T. Chen, X. Cheng, S. Chung, H.-J. Chávez-Fumagalli, M.A. Conway, A. Costa, B.M. Cyr, N. Dean, L.T. Denzel, M.S. Dlamini, S.V. Dudley, K.J. Dufies, M. Ecke, T. Eckweiler, D. Eixarch, E. El-Adawy, H. Emmrich, J.V. Eustace, A.J. Falter-Wagner, C.M. Farhoudi, R. Fuss, J. Gao, J. Gill, M.R. Gloyn, L. Goggs, R. Govinden, U. Greene, G. Greiff, V. Grundle, D.S. Grüneberg, P. Gumede, N. Haore, G. Harrison, P. Hoenner, X. Hojsgaard, D. Hori, H. Ikonomopoulou, M.P. Jeurissen, P. Johnson, D.M. Kabra, D. Kamagata, K. Karmakar, C. Kasian, O. Kaye, L.K. Khan, M.M. Kim, Y.-M. Kish, J.K. Kobold, S. Kohanbash, G. Kohls, G. Kugler, J.-M. Kumar, G. Lacy-Colson, J. Latif, A. Lauschke, V.M. Li, B. Lim, C.J. Liu, F. Liu, X. Lu, J.-J. Lu, Q. Mahavadi, P. Marzocchi, U. McGarrigle, C.A. van Meerten, T. Min, R. Moal, I. Molari, M. Molleman, L. Mondal, S.R. van de Mortel, T. Moss, W.N. Moultos, O.A. Mukherjee, M. Nakayama, K. Narayan, E. Navaratnarajah Neumann, P.-A. Nie, J. Nie, Y. Niemeyer, F. Nolan, F. Nwaiwu, O. Oldenmenger, W.H. Olumayede, E. Ou, J. Pallebage-Gamarallage, M. Pearce, S.P. Pelkonen, T. Pelleri, M.C. Pereira, J.L. 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Christoffersen, T. Comel, J.C. Cosse, C. Cui, Y. van Dessel, P. Dhaval Diodato, D. Duffey, M. Dutt, A. Egea, L.G. El-Said, M. Faye, M. Fernandez-Fernandez, B. Foley, K.G. Founou, L.L. Fu, F. Gadelkareem, R.A. Galimov, E. Garip, G. Gemmill, A. Gouil, Q. Grey, J. Gridneva, Z. Grothe, M.J. Grébert, T. Guerrero, F. Guignard, L. Haenssgen, M.J. Hasler, D. Holgate, J.Y. Huang, A. Hulse-Kemp, A.M. Jean-Quartier, C. Jeon, S.-M. Jia, Y. Jutzeler, C. Kalatzis, P. Karim, M. Karsay, K. Keitel, A. Kempe, A. Keown, J.R. Khoo, C.M. Khwaja, N. Kievit, R.A. Kosanic, S. Koutoukidis, D.A. Kramer, P. Kumar, D. Kiraǧ, N. Lanza, G. Le, T.D. Leem, J.W. Leightley, D. Leite, A. Lercher, L. Li, Y. Lim, R. Lima, L.R.A. Lin, L. Ling, T. Liu, Y. Liu, Z. Lu, Y. Lum, F.M. Luo, H. Machhi, J. Macleod, A. Macwan, I. Madala, H.R. Madani, N. de Maio, N. Makowiecki, K. Mallinson, D.J. Margelyte, R. Maria, C. Markonis, Y. Marsili, L. Mavoa, S. McWilliams, L. Megersa, M. Souto-Maior, C. Menichetti, J. Mercieca-Bebber, R. 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Zaritsky, A. Zhang, Y. Zhao, H. Zuckerman, H. Lyu, R. Pullan, W. RELISH Consortium
- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science. © The Author(s) 2019. Published by Oxford University Press.
- Published
- 2019
9. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
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- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science.
- Published
- 2019
10. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
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Brown, P., Zhou, Y., Tan, A. -C., El-Esawi, M. A., Liehr, T., Blanck, O., Gladue, D. P., Almeida, G. M. F., Cernava, T., Sorzano, C. O., Yeung, A. W. K., Engel, M. S., Chandrasekaran, A. R., Muth, T., Staege, M. S., Daulatabad, S. V., Widera, D., Zhang, J., Meule, A., Honjo, K., Pourret, O., Yin, C. -C., Zhang, Z., Cascella, M., Flegel, W. A., Goodyear, C. S., van Raaij, M. J., Bukowy-Bieryllo, Z., Campana, L. G., Kurniawan, N. A., Lalaouna, D., Huttner, F. J., Ammerman, B. A., Ehret, F., Cobine, P. A., Tan, E. -C., Han, H., Xia, W., Mccrum, C., Dings, R. P. M., Marinello, F., Nilsson, H., Nixon, B., Voskarides, K., Yang, L., Costa, V. D., Bengtsson-Palme, J., Bradshaw, W., Grimm, D. G., Kumar, N., Martis, E., Prieto, D., Sabnis, S. C., Amer, S. E. D. R., Liew, A. W. C., Perco, P., Rahimi, F., Riva, G., Zhang, C., Devkota, H. P., Ogami, K., Basharat, Z., Fierz, W., Siebers, R., Tan, K. H., Boehme, K. A., Brenneisen, P., Brown, J. A. L., Dalrymple, B. P., Harvey, D. 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D., Pedro, S. A., Perry, S. R., Peter, J., Peterson, B. M., Pezzuolo, A., Pozdnyakov, I., Qian, S., Qin, L., Rafe, A., Raote, I., Raza, A., Rebl, H., Refai, O., Regan, T., Richa, T., Richardson, M. F., Robinson, K. R., Rossoni, L., Rouet, R., Safaei, S., Schneeberger, P. H. H., Schwotzer, D., Sebastian, A., Selinski, J., Seltmann, S., Sha, F., Shalev, N., Shang, J. -L., Singer, J., Singh, M., Smith, T., Solomon-Moore, E., Song, L., Soraggi, S., Stanley, R., Steckhan, N., Strobl, F., Subissi, L., Supriyanto, I., Surve, C. R., Suzuki, T., Syme, C., Sorelius, K., Tang, Y., Tantawy, M., Tennakoon, S., Teseo, S., Toelzer, C., Tomov, N., Tovar, M., Tran, L., Tripathi, S., Tuladhar, A. M., Ukubuiwe, A. C., Ung, C. O. L., Valgepea, K., Vatanparast, H., Vidal, A., Wang, Q., Watari, R., Webster, R., Wei, J., Wibowo, D., Wingenbach, T. S. H., Xavier, R. M., Xiao, S., Xiong, P., Xu, S., Yao, R., Yao, W., Yin, Q., Zaitsu, M., Zeineb, Z., Zhan, X. -Y., Zhang, R., Zhang, W., Zheng, S., Zhou, B., Ahmad, H., Akinwumi, S. A., Albery, G. F., Alhowimel, A., Ali, J., Alshehri, M., Alsuhaibani, M., Anikin, A., Azubuike, S. O., Bach-Mortensen, A., Baltiansky, L., Bartas, M., Belachew, K. Y., Bhardwaj, V., Binder, K., Bland, N. S., Boah, M., Bullen, B., Calabro', Giovanna Elisa, Callahan, T. J., Cao, B., Chalmers, K., Chang, W., Che, Z., Chen, A. T. Y., Chen, Z., Choi, Y., Chowdhury, M. A. K., Christensen, M. R., Cooke, R. S. C., Cottini, M., Covington, N. V., Cunningham, C., Delarocque, J., Devos, L., Dhar, A. R., Ding, K. -F., Dong, K., Dong, Z., Dreyer, N., Ekstrand, C., Fardet, T., Feleke, B. E., Feurer, T., Freitas, A., Gao, T., Gebremedhin, Giganti, F., Grabowski, P., Guerra-Mora, J. R., Guo, C., Guo, X., Gupta, H., He, S., Heijne, M., Heinemann, S., Hogrebe, A., Huang, Z., Iskander-Rizk, S., Iyer, L. M., Jahan, Y., James, A. S., Joel, E., Joffroy, B., Jegousse, C., Kambondo, G., Karnati, P., Kaya, C., Ke, A., Kelly, D., Kickert, R., Kidibule, P. E., Kieselmann, J. P., Kim, H. J., Kitazawa, T., Lamberts, A., Liang, H., Linn, S. N., Litfin, T., Liusuo, W., Lygirou, V., Mahato, A. K., Mai, Z. -M., Major, R. W., Mali, S., Mallis, P., Mao, W., Marvin-Dowle, K., Mason, L. D., Merideth, B., Merino-Plaza, M. J., Merlaen, B., Messina, R., Mishra, A. K., Muhammad, J., Musinguzi, C., Nanou, A., Naqash, A., Nguyen, J. T., Nguyen, T. T. H., Ni, D., Nida, Notcovich, S., Ohst, B., Ollivier, Q. R., Osses, D. F., Peng, X., Plantinga, A., Pulia, M., Rafiq, M., Raman, A., Raucher-Chene, Rawski, R., Ray, A., Razak, L. A., Rudolf, K., Rusch, P., Sadoine, M. L., Schmidt, A., Schurr, R., Searles, S., Sharma, S., Sheehan, B., Shi, C., Shohayeb, B., Sommerlad, A., Strehlow, J., Sun, X., Sundar, R., Taherzadeh, G., Tahir, N. D. M., Tang, J., Testa, J., Tian, Z., Tingting, Q., Verheijen, G. P., Vickstrom, C., Wang, T., Wang, X., Wang, Z., Wei, P., Wilson, A., Wyart, Yassine, A. -A., Yousefzadeh, A., Zare, A., Zeng, Z., Zhang, H., Zhou, J., Zhu, D., Adamo, V., Adeyemo, A. A., Aggelidou, M., Al-Owaifeer, A. M., Al-Riyami, A. Z., Alzghari, S. K., Andersen, V., Angus, K., Asaduzzaman, M., Asady, H., Ato, D., Bai, X., Baines, R. L., Ballantyne, M., Ban, B., Beck, J., Ben-Nafa, W., Black, E., Blancher, A., Blankstein, R., Bodagh, N., Borges, P., Brooks, A., Brox-Ponce, J., Brunetti, A., Canham, C. D., Carninci, P., Carvajal, R., Chang, S. C., Chao, J., Chatterjee, P., Chen, L., Chhatriwalla, A. K., Chikowe, I., Chuang, T. -J., Collevatti, R. G., Cornejo, D. A. V., Cuenda, A., Dao, M., Dauga, D., Deng, Z., Devkota, K., Doan, L. V., Elewa, Y. H. A., Fan, D., Faruk, M., Feifei, S., Ferguson, T. S., Fleres, F., Foster, E. J., Foster, S., Furer, T., Gao, Y., Garcia-Rivera, E. J., Gazdar, A., George, R. B., Ghosh, S., Gianchecchi, E., Gleason, J. M., Hackshaw, A., Hall, A., Hall, R., Harper, P., Hogg, W. E., Huang, G., Hunter, K. E., Ijzerman, A. P., Jesus, C., Jian, G., Lewis, J. S., Kanj, S. S., Kaur, H., Kheir, F., Kichatova, V. S., Kiyani, M., Klein, R., Kovesi, T., Kraschnewski, J. L., Kumar, A. P., Labutin, D., Lazo-Langner, A., Leclercq, G., Li, M., Li, Q., Li, T., Liao, W. -T., Liao, Z. -Y., Lin, J., Lizer, J., Lobreglio, G., Lowies, C., Lu, C., Majeed, H., Martin, A., Martinez-Sobrido, L., Meresh, E., Middelveen, M., Mohebbi, A., Mota, J., Mozaheb, Z., Muyaya, L., Nandhakumar, A., Ng, S. H. X., Obeidat, M., Oh, D. -H., Owais, M., Pace-Asciak, P., Panwar, A., Patterson, C., Penagos-Tabaree, F., Pianosi, P. T., Pinzi, V., Pridans, C., Psaroulaki, A., Pujala, R. K., Pulido-Arjona, L., Qi, P. -F., Rahman, P., Rai, N. K., Rassaf, T., Refardt, J., Ricciardi, Walter, Riess, O., Rovas, A., Sacks, F. M., Saleh, S., Sampson, C., Schmutz, A., Sepanski, R., Sharma, N., Spearman, P., Subramaniapillai, M., Swali, R., Tan, C. M., Tellechea, J. I., Thomas, L. -M., Tong, X., Vavvas, D. G., Veys, R., Vitriol, V., Wang, H. -D., Waugh, J., Webb, S. A., Williams, B. A., Workman, A. D., Xiang, T., Xie, L. -X., Xu, T., Yang, C., Yoon, J. G., Yuan, C. M., Zaritsky, A., Zhao, H., Zuckerman, H., Lyu, R., Pullan, W., Calabro G. E. (ORCID:0000-0003-0259-3797), and Ricciardi W. (ORCID:0000-0002-5655-688X)
- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science.
- Published
- 2019
11. Decision-making in obesity without eating disorders: a systematic review and meta-analysis of Iowa gambling task performances
- Author
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Rotge, J. Y., Poitou, Christine, Fossati, P., Aron-Wisnewsky, J., Oppert, J.-M., Service de psychiatrie adulte [CHU Pitié-Salpêtière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-CHU Pitié-Salpêtrière [AP-HP], Service de nutrition [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], HAL-UPMC, Gestionnaire, Service de Psychiatrie Adulte [CHU Pitié-Salpêtière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Service de Nutrition [CHU Pitié-Salpétrière], Institut E3M [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), and Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP]
- Subjects
[SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism ,[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition ,Meta-analysis ,[SCCO]Cognitive science ,Obesity words ,Iowa Gambling Task ,[SCCO] Cognitive science ,[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,Decision-making - Abstract
International audience; Background: There is evidence that obesity is associated with impairments in executive functions, such as deficits in decision-making, planning or problem solving, which might interfere with weight loss in obese individuals. We performed a systematic review and meta-analysis of decision-making abilities, as measured with the Iowa gambling task (IGT), in obesity without eating disorders.Methods: A systematic search was conducted to identify studies comparing IGT performances between groups of obese patients without eating disorders and groups of healthy control groups. The standardized mean differences were calculated for the total IGT scores and for the course of IGT scores. Meta-regression analyses were performed to explore the influence of clinical variables on standardized mean differences.Results: Total IGT scores were significantly lower in obese patients compared with normal-weight healthy controls. IGT performances did not differ between groups for the first trials of the task. Significant effect sizes for the last trials of the task were subjected to a high degree of heterogeneity.Conclusion: Risky decision-making is impaired in obesity. The clinical importance of non-food-related decision-making impairments remains to be assessed especially in terms of consequences in daily life or the achievement of weight loss.
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- 2017
12. Facteurs prédictifs de la réponse antidépressive à la kétamine dans les épisodes dépressifs majeurs résistants : revue de la littérature
- Author
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Romeo, B., primary, Choucha, W., additional, Fossati, P., additional, and Rotge, J.-Y., additional
- Published
- 2017
- Full Text
- View/download PDF
13. A video Clinical Global Impression (CGI) in obsessive compulsive disorder
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Bourredjem, A, Pelissolo, A, Rotge, J.-Y., Jaafari, N, Machefaux, S, Quentin, S, Bui, E, Bruno, N, Pochon, J.-B., Polosan, M, Baup, N, Papetti, F, Chéreau, I, Arbus, C, Mallet, L, Tezenas Du Montcel, Sophie, (STOC), French Stimulation dans le trouble obsessionnel compulsif study group, Magnié-Mauro, Marie-Noële, Laboratoire de psychologie cognitive et sociale (LPCS), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), The French 'Stimulation dans le Trouble Obsessionnel Compulsif (STOC)' Study Group, Centre d'Investigation Clinique 1432 (Dijon) - Epidemiologie Clinique/Essais Cliniques (CIC-EC), Université de Bourgogne (UB)-Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de psychiatrie adulte [CHU Pitié-Salpêtière], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), CIC - Poitiers, Université de Poitiers-Centre hospitalier universitaire de Poitiers (CHU Poitiers)-Direction Générale de l'Organisation des Soins (DGOS)-Institut National de la Santé et de la Recherche Médicale (INSERM), ANTE-INSERM U836, équipe 11, Fonctions cérébrales et neuromodulation, Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de psychiatrie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-Hôpital Sainte-Anne, CHU Clermont-Ferrand, Service Anatomie et cytologie pathologiques [CHU Toulouse], Pôle Biologie [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service d'anatomie et cytologie pathologiques [Purpan], Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Pollak, Pierre, Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Université Paris Descartes - Paris 5 (UPD5)-Hôpital Sainte-Anne, Service d'informatique médicale, Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], Centre d'Investigation Clinique 1432 (Dijon) - Epidemiologie Clinique/Essais Cliniques ( CIC-EC ), Université de Bourgogne ( UB ) -Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand ( CHU Dijon ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Service de psychiatrie adulte, Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Pitié-Salpêtrière [APHP], Université de Poitiers-CHU de Poitiers-Direction Générale de l'Organisation des Soins (DGOS)-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Grenoble Institut des Neurosciences ( GIN ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -CHU Grenoble-Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -CHU Grenoble-Université Joseph Fourier - Grenoble 1 ( UJF ), Assistance publique - Hôpitaux de Paris (AP-HP)-Université Paris Descartes - Paris 5 ( UPD5 ) -Hôpital Sainte-Anne, Université Paul Sabatier - Toulouse 3 ( UPS ) -CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Pitié-Salpêtrière [APHP], Université de Poitiers-Centre hospitalier universitaire de Poitiers ( CHU Poitiers ) -Direction Générale de l'Organisation des Soins (DGOS)-Institut National de la Santé et de la Recherche Médicale ( INSERM ), and Université Toulouse III - Paul Sabatier ( UPS )
- Subjects
Adult ,Male ,Video Recording/methods ,medicine.medical_specialty ,Obsessive-Compulsive Disorder ,Time Factors ,Intraclass correlation ,Deep Brain Stimulation ,[SDV]Life Sciences [q-bio] ,Video Recording ,Severity of Illness Index ,Statistics, Nonparametric ,03 medical and health sciences ,0302 clinical medicine ,Obsessive-Compulsive Disorder/diagnosis/therapy ,Double-Blind Method ,Subthalamic Nucleus ,Deep Brain Stimulation/methods ,medicine ,Humans ,Biological Psychiatry ,Reliability (statistics) ,Face validity ,Psychiatric Status Rating Scales ,Cross-Over Studies ,[ SDV ] Life Sciences [q-bio] ,business.industry ,[SCCO.NEUR]Cognitive science/Neuroscience ,Reproducibility of Results ,Usability ,Middle Aged ,Crossover study ,030227 psychiatry ,ddc:616.8 ,Clinical trial ,Psychiatry and Mental health ,Subthalamic Nucleus/physiology ,Scale (social sciences) ,[SCCO.PSYC]Cognitive science/Psychology ,Physical therapy ,Clinical Global Impression ,Female ,Psychology ,business ,030217 neurology & neurosurgery ,Clinical psychology ,Follow-Up Studies - Abstract
International audience; The Clinical Global Impression scale (CGI) is frequently used in clinical research because of its face validity and ease of use but data on its reliability are scarce. Our goal was to estimate the reliability of the scale and compare reliability between face-to-face and video scoring. We analyzed 50 different video interviews recorded during 5 visits of a crossover trial to study the effect of subthalamic nucleus stimulation. Six specialized clinicians rated the CGI using these videos, providing 300 different ratings. The intraclass correlation was lower at inclusion (0.30 [0.13-0.50]) than at later visits (0.68 [0.61-0.80]). Reliability was not influenced by the patients' stimulation status. The mean of at least two independent evaluations of the video is needed to achieve an ICC greater than 0.8. The video CGI is a valid clinical outcome measure suitable for clinical trials (ClinicalTrials.gov number, NCT00169377).
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- 2011
14. Insight, obsession et vérification dans le trouble obsessionnel-compulsif
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Jaafari, N., Daniel, M.-L., Lacoste, J., Bacconnier, M., Belin, D., and Rotge, J.-Y.
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- 2011
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15. Differential role of visuospatial working memory in the propensity toward uncertainty in patients with obsessive–compulsive disorder and in healthy subjects
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Lambrecq, V., primary, Rotge, J.-Y., additional, Jaafari, N., additional, Aouizerate, B., additional, Langbour, N., additional, Bioulac, B., additional, Liégeois-Chauvel, C., additional, Burbaud, P., additional, and Guehl, D., additional
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- 2013
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16. The associative and limbic thalamus in the pathophysiology of obsessive-compulsive disorder: an experimental study in the monkey
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Rotge, J Y, primary, Aouizerate, B, additional, Amestoy, V, additional, Lambrecq, V, additional, Langbour, N, additional, Nguyen, T H, additional, Dovero, S, additional, Cardoit, L, additional, Tignol, J, additional, Bioulac, B, additional, Burbaud, P, additional, and Guehl, D, additional
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- 2012
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17. Evolution of brain gray matter loss in Huntington's disease: a meta-analysis
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Lambrecq, V., primary, Langbour, N., additional, Guehl, D., additional, Bioulac, B., additional, Burbaud, P., additional, and Rotge, J.-Y., additional
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- 2012
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18. Les mouvements oculaires comme moyen de contourner l’insight lors de l’évaluation des comportements de vérification dans le trouble obsessionnel compulsif (TOC)
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Jaafari, N., primary, Frasca, M., additional, Rigalleau, F., additional, Rotge, J.-Y., additional, and Vibert, N., additional
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- 2011
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19. ECT as a 'therapeutic test' to differentiate pharmaco-resistant depression from dementia in the elderly: a pilot study.
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JAAFARI, N., BRZOZOWSKI, M., ROTGE, J. Y., SHAROV, I., BATES, H., PAILLOT, C., DEBAENE, B., CAMUS, V., EL HAGE, W., QUENTIN, S., MILLET, B., and SENON, J. L.
- Abstract
Objectives: Traditionally, if depression is suspected in elderly patients with cognitive disorders, antidepressant therapy is administered during the first three months of diagnosis, in order to treat a comorbid depression that could ultimately compound cognitive impairments. However, antidepressants are only effective in 50-60% of such cases, and their use in elderly populations should be restricted due to their potential negative side effects. In order to offer an alternative treatment strategy, several cases are described where electroconvulsive therapy (ECT) was used as a 'therapeutic test' for the presence of depression. Methods: Eight patients with a diagnosis of 'probable dementia; depression remains to be eliminated' were included in the present study. Following a negative 'antidepressant test', an 'ECT test' was performed. Results: Five patients recovered satisfactorily from depression and cognitive impairments. This improvement persisted for 14 months after the final ECT session. Conclusions: Results suggest that ECT could be used as a potential therapeutic test in elderly subjects with cognitive impairments when depression is suspected. [ABSTRACT FROM AUTHOR]
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- 2008
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20. Bidirectional regulation over the development and expression of loss of control over cocaine intake by the anterior insula
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Rotge, J-Y, Cocker, PJ, Daniel, M-L, Belin-Rauscent, A, Everitt, BJ, and Belin, D
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escalation ,cocaine ,addiction ,anterior insula ,3. Good health - Abstract
$\textbf{RATIONALE}$: Increasing evidence suggests that the anterior insular cortex (AIC) plays a major role in cocaine addiction, being implicated in both impaired insight and associated decision-making and also craving and relapse. However, the nature of the involvement of the insula in the development and maintenance of cocaine addiction remains unknown, thereby limiting our understanding of its causal role in addiction. We therefore investigated whether pre- and post-training bilateral lesions of the AIC differentially influenced the development and the expression of the escalation of cocaine self-administration during extended access to the drug. $\textbf{METHODS}$: In a series of experiments, Sprague Dawley rats received bilateral excitotoxic lesions of the AIC either prior to, or after 3 weeks of training under 12-h extended self-administration conditions, which are known to promote a robust escalation of intake. We also investigated the influence of AIC lesions on anxiety, as measured in an elevated plus maze and sensitivity to conditioned stimuli (CS)- or drug-induced reinstatement of an extinguished instrumental response. $\textbf{RESULTS}$: Whereas, post-escalation lesions of the AIC, as anticipated, restored control over cocaine intake and prevented drug-induced reinstatement, pre-training lesions resulted in a facilitation of the development of loss of control with no influence over the acquisition of cocaine self-administration or anxiety. $\textbf{CONCLUSIONS}$: AIC lesions differentially affect the development and maintenance of the loss of control over cocaine intake, suggesting that the nature of the contribution of cocaine-associated interoceptive mechanisms changes over the course of escalation and may represent an important component of addiction.
21. 2 - Traitements pharmacologiques du trouble obsessionnel-compulsif
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Rotgé, J.-Y.
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22. Auteurs
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Aouizerate, B. and Rotgé, J.-Y.
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23. [Clinical and biological predictors of ketamine response in treatment-resistant major depression: Review].
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Romeo B, Choucha W, Fossati P, and Rotge JY
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- Depressive Disorder, Major drug therapy, Depressive Disorder, Treatment-Resistant genetics, Depressive Disorder, Treatment-Resistant psychology, Gene Expression, Humans, Neuropsychological Tests, Prognosis, Treatment Outcome, Antidepressive Agents therapeutic use, Depressive Disorder, Treatment-Resistant drug therapy, Ketamine therapeutic use
- Abstract
Objective: The aim of this review was to determine the clinical and biological predictors of the ketamine response., Methods: A systematic research on PubMed and PsycINFO database was performed without limits on year of publication., Results: The main predictive factors of ketamine response, which were found in different studies, were (i) a family history of alcohol dependence, (ii) unipolar depressive disorder, and (iii) neurocognitive impairments, especially a slower processing speed. Many other predictive factors were identified, but not replicated, such as personal history of alcohol dependence, no antecedent of suicide attempt, anxiety symptoms. Some biological factors were also found such as markers of neural plasticity (slow wave activity, brain-derived neurotrophic factor Val66Met polymorphism, expression of Shank 3 protein), other neurologic factors (anterior cingulate activity, concentration of glutamine/glutamate), inflammatory factors (IL-6 concentration) or metabolic factors (concentration of B12 vitamin, D- and L-serine, alterations in the mitochondrial β-oxidation of fatty acids). This review had several limits: (i) patients had exclusively resistant major depressive episodes which represent a sub-type of depression and not all depression, (ii) response criteria were more frequently assessed than remission criteria, it was therefore difficult to conclude that these predictors were similar, and finally (iii) many studies used a very small number of patients., Conclusions: In conclusion, this review found that some predictors of ketamine response, like basal activity of anterior cingulate or vitamin B12 concentration, were identical to other therapeutics used in major depressive episode. These factors could be more specific to the major depressive episode and not to the ketamine response. Others, like family history of alcohol dependence, body mass index, or D- and L-serine were different from the other therapeutics. Neurocognitive impairments like slower speed processing or alterations in attention tests were also predictive to a good response. These predictive factors could be more specific to ketamine. With these different predictor factors (clinical and biological), it could be interesting to develop clinical strategies to personalize ketamine's administration., (Copyright © 2016 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.)
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- 2017
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24. Decision-making in obesity without eating disorders: a systematic review and meta-analysis of Iowa gambling task performances.
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Rotge JY, Poitou C, Fossati P, Aron-Wisnewsky J, and Oppert JM
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- Gambling psychology, Humans, Decision Making physiology, Games, Experimental, Obesity psychology
- Abstract
Background: There is evidence that obesity is associated with impairments in executive functions, such as deficits in decision-making, planning or problem solving, which might interfere with weight loss in obese individuals. We performed a systematic review and meta-analysis of decision-making abilities, as measured with the Iowa gambling task (IGT), in obesity without eating disorders., Methods: A systematic search was conducted to identify studies comparing IGT performances between groups of obese patients without eating disorders and groups of healthy control groups. The standardized mean differences were calculated for the total IGT scores and for the course of IGT scores. Meta-regression analyses were performed to explore the influence of clinical variables on standardized mean differences., Results: Total IGT scores were significantly lower in obese patients compared with normal-weight healthy controls. IGT performances did not differ between groups for the first trials of the task. Significant effect sizes for the last trials of the task were subjected to a high degree of heterogeneity., Conclusion: Risky decision-making is impaired in obesity. The clinical importance of non-food-related decision-making impairments remains to be assessed especially in terms of consequences in daily life or the achievement of weight loss. This meta-analysis has been registered in the Prospero database (CRD42016037533)., (© 2017 World Obesity Federation.)
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- 2017
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25. The glutamate-based genetic immune hypothesis in obsessive-compulsive disorder. An integrative approach from genes to symptoms.
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Rotge JY, Aouizerate B, Tignol J, Bioulac B, Burbaud P, and Guehl D
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- Animals, Brain pathology, Brain physiopathology, Excitatory Amino Acid Transporter 3 genetics, Excitatory Amino Acid Transporter 3 metabolism, Humans, Obsessive-Compulsive Disorder genetics, Obsessive-Compulsive Disorder immunology, Obsessive-Compulsive Disorder pathology, Glutamic Acid metabolism, Models, Neurological, Obsessive-Compulsive Disorder physiopathology
- Abstract
Recent advances in multiple areas of research have contributed to the identification of several pathophysiological factors underlying obsessive-compulsive disorder (OCD). In particular, the glutamate transporter gene SLC1A1 has been associated with the diagnosis of OCD. Immunological and infectious studies have reported alterations of the immune system and the presence of immune complexes directed against the Borna disease virus in OCD patients. In addition, neuroimaging of OCD patients has demonstrated abnormalities in the anterior cingulate cortex, orbitofrontal cortex, thalamus, and the basal ganglia. Neuropsychological assessments have found several cognitive disruptions that have been identified in OCD, especially impairments in cognitive flexibility. Here, we attempt to bridge the gap between these remarkable findings through several previously unpredicted pathophysiological mechanisms. We propose an integrative hypothesis that indicates how genetic and environmental factors may contribute to the structural and functional alterations of cortico-subcortical circuits, leading to the characteristic cognitive disruptions underlying OCD symptoms.
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- 2010
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