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1. Mass testing and characterization of 20-inch PMTs for JUNO

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Abid Aleem, Tsagkarakis Alexandros, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Weidong Bai, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Jose Busto, Ilya Butorov, Anatael Cabrera, Barbara Caccianiga, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Chi Chan, Jinfan Chang, Yun Chang, Guoming Chen, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yixue Chen, Yu Chen, Zhiyuan Chen, Zikang Chen, Jie Cheng, Yaping Cheng, Yu Chin Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Marta Colomer Molla, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Zhengyong Fei, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Yuduo Guan, Nunzio Guardone, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Yuxiang Hu, Zhuojun Hu, Guihong Huang, Hanxiong Huang, Kaixuan Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Ignacio Jeria, Xiaolu Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Amina Khatun, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Daozheng Li, Demin Li, Fei Li, Fule Li, Gaosong Li, Huiling Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Rui Li, Shanfeng Li, Tao Li, Teng Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yichen Li, Yufeng Li, Zepeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Zonghai Li, Hao Liang, Jiajun Liao, Ayut Limphirat, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Haotian Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Daibin Luo, Fengjiao Luo, Guang Luo, Shu Luo, Wuming Luo, Xiaojie Luo, Vladimir Lyashuk, Bangzheng Ma, Bing Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Jingyu Mai, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Luca Pelicci, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Yu Peng, Zhaoyuan Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Mariia Redchuk, Bin Ren, Jie Ren, Barbara Ricci, Mariam Rifai, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Xichao Ruan, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Utane Sawangwit, Julia Sawatzki, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Jun Su, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Zhengyang Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Eric Theisen, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Katharina von Sturm, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiang Xiao, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhao Xin, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Jiaxuan Ye, Mei Ye, Ziping Ye, Frédéric Yermia, Na Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Cenxi Yuan, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Baobiao Yue, Noman Zafar, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Bin Zhang, Binting Zhang, Feiyang Zhang, Guoqing Zhang, Honghao Zhang, Jialiang Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Mohan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xin Zhang, Xuantong Zhang, Xueyao Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yu Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Runze Zhao, Shujun Zhao, Dongqin Zheng, Hua Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Jingsen Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Main goal of the JUNO experiment is to determine the neutrino mass ordering using a 20 kt liquid-scintillator detector. Its key feature is an excellent energy resolution of at least 3% at 1 MeV, for which its instruments need to meet a certain quality and thus have to be fully characterized. More than 20,000 20-inch PMTs have been received and assessed by JUNO after a detailed testing program which began in 2017 and elapsed for about four years. Based on this mass characterization and a set of specific requirements, a good quality of all accepted PMTs could be ascertained. This paper presents the performed testing procedure with the designed testing systems as well as the statistical characteristics of all 20-inch PMTs intended to be used in the JUNO experiment, covering more than fifteen performance parameters including the photocathode uniformity. This constitutes the largest sample of 20-inch PMTs ever produced and studied in detail to date, i.e. 15,000 of the newly developed 20-inch MCP-PMTs from Northern Night Vision Technology Co. (NNVT) and 5000 of dynode PMTs from Hamamatsu Photonics K. K.(HPK).

Published
2022
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2. Model-independent Approach of the JUNO 8B Solar Neutrino Program

Author

Jie Zhao, Baobiao Yue, Haoqi Lu, Yufeng Li, Jiajie Ling, Zeyuan Yu, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Abid Aleem, Tsagkarakis Alexandros, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Weidong Bai, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Jose Busto, Ilya Butorov, Anatael Cabrera, Barbara Caccianiga, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Chi Chan, Jinfan Chang, Yun Chang, Guoming Chen, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yixue Chen, Yu Chen, Zhiyuan Chen, Zikang Chen, Jie Cheng, Yaping Cheng, Alexander Chepurnov, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Marta Colomer Molla, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Zhengyong Fei, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Maxim Gromov, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Yuduo Guan, Nunzio Guardone, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Yuxiang Hu, Zhuojun Hu, Guihong Huang, Hanxiong Huang, Kaixuan Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Ignacio Jeria, Xiaolu Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Xiaoping Jing, Cécile Jollet, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Amina Khatun, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Daozheng Li, Demin Li, Fei Li, Fule Li, Gaosong Li, Huiling Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Rui Li, Shanfeng Li, Tao Li, Teng Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yichen Li, Zepeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Zonghai Li, Hao Liang, Jiajun Liao, Ayut Limphirat, Guey-Lin Lin, Shengxin Lin, Tao Lin, Ivano Lippi, Fang Liu, Haidong Liu, Haotian Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Daibin Luo, Fengjiao Luo, Guang Luo, Shu Luo, Wuming Luo, Xiaojie Luo, Vladimir Lyashuk, Bangzheng Ma, Bing Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Jingyu Mai, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Alexey Nikolaev, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Yu Peng, Zhaoyuan Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Mariia Redchuk, Bin Ren, Jie Ren, Barbara Ricci, Mariam Rifai, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Xichao Ruan, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Utane Sawangwit, Julia Sawatzki, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Jun Su, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Zhengyang Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Katharina von Sturm, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiang Xiao, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhao Xin, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Jiaxuan Ye, Mei Ye, Ziping Ye, Frédéric Yermia, Na Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zezhong Yu, Cenxi Yuan, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Noman Zafar, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Bin Zhang, Binting Zhang, Feiyang Zhang, Guoqing Zhang, Honghao Zhang, Jialiang Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Mohan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xin Zhang, Xuantong Zhang, Xueyao Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yu Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Rong Zhao, Runze Zhao, Shujun Zhao, Dongqin Zheng, Hua Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Jingsen Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Solar neutrinos, Astrophysics, QB460-466
Abstract

The physics potential of detecting ^8 B solar neutrinos will be exploited at the Jiangmen Underground Neutrino Observatory (JUNO), in a model-independent manner by using three distinct channels of the charged current (CC), neutral current (NC), and elastic scattering (ES) interactions. Due to the largest-ever mass of ^13 C nuclei in the liquid scintillator detectors and the expected low background level, ^8 B solar neutrinos are observable in the CC and NC interactions on ^13 C for the first time. By virtue of optimized event selections and muon veto strategies, backgrounds from the accidental coincidence, muon-induced isotopes, and external backgrounds can be greatly suppressed. Excellent signal-to-background ratios can be achieved in the CC, NC, and ES channels to guarantee the observation of the ^8 B solar neutrinos. From the sensitivity studies performed in this work, we show that JUNO, with 10 yr of data, can reach the 1 σ precision levels of 5%, 8%, and 20% for the ^8 B neutrino flux, ${\sin }^{2}{\theta }_{12}$ , and ${\rm{\Delta }}{m}_{21}^{2}$ , respectively. Probing the details of both solar physics and neutrino physics would be unique and helpful. In addition, when combined with the Sudbury Neutrino Observatory measurement, the world's best precision of 3% is expected for the measurement of the ^8 B neutrino flux.

Published
2024
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3. Damping signatures at JUNO, a medium-baseline reactor neutrino oscillation experiment

Author

The JUNO collaboration, Jun Wang, Jiajun Liao, Wei Wang, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We study damping signatures at the Jiangmen Underground Neutrino Observatory (JUNO), a medium-baseline reactor neutrino oscillation experiment. These damping signatures are motivated by various new physics models, including quantum decoherence, ν 3 decay, neutrino absorption, and wave packet decoherence. The phenomenological effects of these models can be characterized by exponential damping factors at the probability level. We assess how well JUNO can constrain these damping parameters and how to disentangle these different damping signatures at JUNO. Compared to current experimental limits, JUNO can significantly improve the limits on τ 3/m 3 in the ν 3 decay model, the width of the neutrino wave packet σ x , and the intrinsic relative dispersion of neutrino momentum σ rel.

Published
2022
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4. The design and sensitivity of JUNO’s scintillator radiopurity pre-detector OSIRIS

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Jiajun Liao, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, MinhThuan NguyenThi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangpu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The OSIRIS detector is a subsystem of the liquid scintillator filling chain of the JUNO reactor neutrino experiment. Its purpose is to validate the radiopurity of the scintillator to assure that all components of the JUNO scintillator system work to specifications and only neutrino-grade scintillator is filled into the JUNO Central Detector. The aspired sensitivity level of $$10^{-16}\hbox { g/g}$$ 10 - 16 g/g of $$^{238}\hbox {U}$$ 238 U and $$^{232}\hbox {Th}$$ 232 Th requires a large ( $$\sim 20\,\hbox {m}^3$$ ∼ 20 m 3 ) detection volume and ultralow background levels. The present paper reports on the design and major components of the OSIRIS detector, the detector simulation as well as the measuring strategies foreseen and the sensitivity levels to U/Th that can be reached in this setup.

Published
2021
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5. Radioactivity control strategy for the JUNO detector

Author

The JUNO collaboration, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Oliviero Cremonesi, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jiajun Liao, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Moritz Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract JUNO is a massive liquid scintillator detector with a primary scientific goal of determining the neutrino mass ordering by studying the oscillated anti-neutrino flux coming from two nuclear power plants at 53 km distance. The expected signal anti-neutrino interaction rate is only 60 counts per day (cpd), therefore a careful control of the background sources due to radioactivity is critical. In particular, natural radioactivity present in all materials and in the environment represents a serious issue that could impair the sensitivity of the experiment if appropriate countermeasures were not foreseen. In this paper we discuss the background reduction strategies undertaken by the JUNO collaboration to reduce at minimum the impact of natural radioactivity. We describe our efforts for an optimized experimental design, a careful material screening and accurate detector production handling, and a constant control of the expected results through a meticulous Monte Carlo simulation program. We show that all these actions should allow us to keep the background count rate safely below the target value of 10 Hz (i.e. ∼1 cpd accidental background) in the default fiducial volume, above an energy threshold of 0.7 MeV.

Published
2021
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6. JUNO sensitivity to low energy atmospheric neutrino spectra

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Eric Baussan, Marco Bellato, Antonio Bergnoli, Enrico Bernieri, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Oleg Gorchakov, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Qinhua Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Antonio Insolia, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Zinovy Krumshteyn, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Salvatore Monforte, Paolo Montini, Michele Montuschi, Axel Müller, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Taras Rezinko, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Giuseppe Salamanna, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Jacky Schuler, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Moritz Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Wenjie Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and The JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Atmospheric neutrinos are one of the most relevant natural neutrino sources that can be exploited to infer properties about cosmic rays and neutrino oscillations. The Jiangmen Underground Neutrino Observatory (JUNO) experiment, a 20 kton liquid scintillator detector with excellent energy resolution is currently under construction in China. JUNO will be able to detect several atmospheric neutrinos per day given the large volume. A study on the JUNO detection and reconstruction capabilities of atmospheric $$\nu _e$$ ν e and $$\nu _\mu $$ ν μ fluxes is presented in this paper. In this study, a sample of atmospheric neutrino Monte Carlo events has been generated, starting from theoretical models, and then processed by the detector simulation. The excellent timing resolution of the 3” PMT light detection system of JUNO detector and the much higher light yield for scintillation over Cherenkov allow to measure the time structure of the scintillation light with very high precision. Since $$\nu _e$$ ν e and $$\nu _\mu $$ ν μ interactions produce a slightly different light pattern, the different time evolution of light allows to discriminate the flavor of primary neutrinos. A probabilistic unfolding method has been used, in order to infer the primary neutrino energy spectrum from the detector experimental observables. The simulated spectrum has been reconstructed between 100 MeV and 10 GeV, showing a great potential of the detector in the atmospheric low energy region.

Published
2021
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7. Calibration strategy of the JUNO experiment

Author

The JUNO collaboration, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Eric Baussan, Marco Bellato, Antonio Bergnoli, Enrico Bernieri, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Shenjian Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Anna Chuvashova, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Georgy Donchenko, Jianmeng Dong, Damien Dornic, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Marco Fargetta, Anna Fatkina, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Alexandre Göttel, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Franco Giuliani, Maxim Gonchar, Guanghua Gong, Hui Gong, Oleg Gorchakov, Yuri Gornushkin, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Qinhua Huang, Wenhao Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Antonio Insolia, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Amir Khan, Waseem Khan, Khanchai Khosonthongkee, Patrick Kinz, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Svetlana Krokhaleva, Zinovy Krumshteyn, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Jin Li, Kaijie Li, Mengzhao Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Shuaijie Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hu Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Yan Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Axel Müller, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Salvatore Monforte, Paolo Montini, Michele Montuschi, Nikolay Morozov, Waqas Muhammad, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Teerapat Payupol, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Luis Felipe Piñeres Rico, Oliver Pilarczyk, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Taras Rezinko, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Giuseppe Salamanna, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Jacky Schuler, Cédric Schwab, Konstantin Schweizer, Dmitry Selivanov, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Jingyan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondrej Sramek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Stefan van Waasen, Johannes van den Boom, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cristina Volpe, Vit Vorobel, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Wenjie Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Mengjiao Xiao, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Xiang Zhou, Jiang Zhu, Kejun Zhu, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We present the calibration strategy for the 20 kton liquid scintillator central detector of the Jiangmen Underground Neutrino Observatory (JUNO). By utilizing a comprehensive multiple-source and multiple-positional calibration program, in combination with a novel dual calorimetry technique exploiting two independent photosensors and readout systems, we demonstrate that the JUNO central detector can achieve a better than 1% energy linearity and a 3% effective energy resolution, required by the neutrino mass ordering determination.

Published
2021
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8. Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients

Author

Sebastiano, Cicco, D'Abbondanza, Marco, Proietti, Marco, Vincenzo, Zaccone, Chiara, Pes, Federica, Caradio, Mattioli, Massimo, Salvatore, Piano, Alberto Maria Marra, Alessandro, Nobili, Pier Mannuccio Mannucci, Antonello, Pietrangelo, Giorgio, Sesti, Elena, Buzzetti, Andrea, Salzano, Antonio, Cimellaro, Francesco, Perticone, Francesco, Violi, Gino Roberto Corazza, Salvatore, Corrao, Alessandra, Marengoni, Francesco, Salerno, Matteo, Cesari, Mauro, Tettamanti, Luca, Pasina, Carlotta, Franchi, Alessio, Novella, Gabriella, Miglio, Alessia Antonella Galbussera, Ilaria, Ardoino, Prisco, Domenico, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Michele, Zaccari, Massimiliano, Chiuch, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Pirro, Matteo, Lupattelli, Graziana, Bianconi, Vanessa, Alcidi, Riccardo, Giotta, Alessia, Massimo, R Mannarino, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Christiano, Argano, Federica, Cavallaro, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Serafini, Giovanni, Angelo, Simili, Mattia, Brunori, Ilaria, Lazzari, Cappellini, MARIA DOMENICA, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Valeria Di Stefano, Simona, Leoni, Sonia, Seghezzi, Alessandra Danuto Di Mauro, Diletta, Maira, Marta, Mancarella, Tiziano, Lucchi, Paolo Dionigi Rossi, Marta, Clerici, Alessandra Danuta Di Mauro, Giulia, Bonini, Conti, Federica, Silvia, Prolo, Maddalena, Fabrizi, Miriana, Martelengo, Giulia, Vigani, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Lavinia, Pitotti, Donatella, Padula, Valentina, Antoci, Ginevra, Cambiè, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Jacopo, Alberto, Federico, Cattaneo, Luigi, Anastasio, Lucia, Sofia, Carbone, LUIGI MARIA, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Emanuele, Valeriani, Damiani, D'Ardes, Lucia, Esposito, Simona, Sestili, Ermanno, Angelucci, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Giovanni, Imbimbo, Giuseppe, Zuccalà, Gabriella, D'Aurizio, Giuseppe, Romanelli, Andrea, Volpini, Daniela, Lucente, Francesca, Manzoni, Annalisa, Pirozzi, Alberto, Zucchelli, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Chiara, Dell'Unto, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Alessandra, Bonfanti, Hajnalka, Szabo, Mazzola, Paolo, Piazzoli, Andrea, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio, Brucato, Teresa De Falco, Enrica, Negro, Martino, Brenna, Lucia, Trotta, Giovanni Lorenzo Squintani, Maria Luisa Randi, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Francesco, Ratti, Chiara, Zurlo, Lorenzo, Cerruti, Elisabetta, Cosi, Roberto, Manfredini, Fabio, Fabbian, Benedetta, Boari, Alfredo De Giorgi, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Irene Di Meo, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Francesca Giulia Leoni, Valeria De Sando, Sara, Scarduelli, Michela, Cammarosano, Ilenia, Pareo, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Giuseppe, Re, Andrea, Schilardi, Francesca, Loparco, Luigi, Fenoglio, Andrea, Falcetta, Alessia Valentina Giraudo, Salvatore, D'Aniano, Anna, L Fracanzani, Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Felice, Cinque, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Erica, Pagliaro, Eleonora, Semproni, Canetta, Ciro, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Christian, Folli, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Salam, Kassem, Luca, Liberale, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Camillo, Ferrandina, Francesca, Mazzeo, Elena, Spazzini, Giulia, Cono, Giulia, Cesaroni, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Ludovica, Perri, Luigina, Guasti, Francesca, Rotunno, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Francesco, Dentali, Bertolotti, Marco, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Elena, Bigi, Pellegrini, Elisa, Laura, Orlandi, Giulia, Dondi, Lucia, Carulli, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Aleandra, Scozzafava, Valentino, Condoleo, Tania, Falbo, Lidia, Colangelo, Marco, Filice, Elvira, Clausi, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara Del Vecchio, Ilaria, Benzoni, Andrea, Salvi, Leonardi, Roberto, Giampaolo, Damiani, Gianluca, Moroncini, William, Capeci, Giuseppe Pio Martino, Biondi, Lorenzo, Pietro, Pettinari, Monica, Ormas, Emanuele, Filippini, Devis, Benfaremo, Roberto, Romiti, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Samuele, Pignataro, Francesca, Mete, Miriam, Gino, Guido, Moreo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Paolo, Setti, Chiara, Traversa, Camilla, Scarsi, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Marcello Giuseppe Maggio Gian Paolo Ceda, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giovanni, Paoletti, Francesca, Losa, Montalto, GIUSEPPE ALBERT, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Mecocci, Patrizia, Ruggiero, Carmelinda, Boccardi, Virginia, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Sarah, Morellini, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Tarquini, Roberto, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Volpi, Riccardo, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, Federica, Gandolfo, Franco Laghi Pasini, Pier Leopoldo Capecchi, Ranuccio, Nuti, Roberto, Valenti, Martina, Ruvio, Silvia, Cappelli, Alberto, Palazzuoli, Mauro, Bernardi, Silvia Li Bassi, Luca, Santi, Giacomo, Zaccherini, Vittorio, Durante, Daniela, Tirotta, Giovanna, Eusebi, Cattaneo, Marco Natale, Amoruso, MARIA VALENTINA, Paola, Fracasso, Cristina, Fasolino, Moreno, Tresoldi, Enrica, Bozzolo, Sarah, Damanti, Massimo, Porta, Giuseppe, Armentaro, Maria Immacolata Arnone, Milena, Barone, Lorenzo, Bertolino, Sara, Bianco, Nicolò, Binello, Simona, Brancati, Agostino, Buonauro, William, Cordeddu, Curcio, Rosa, Andrea, Dalbeni, Salvatore, D'Agnano, Damiano, D'Ardes, Martina De Feo, Emilia, Donnarumma, Marco, Fei, Carmine Gabriele Gambino, Paolo, Giorgini, Lombardi, Rosa, Giuseppe, Miceli, Paola, Naccarato, Silvia, Noviello, Gaia, Olivieri, Roberta, Parente, Francesca Serena Pignataro, Sonia, Poma, Enrica, Porceddu, Pucci, Giacomo, Marco, Ricchio, Anna, Sabena, Marco, Salice, Claudia, Santarossa, Ambra, Savona, Caterina, Savrié, Roberto, Scicali, Mario, Stabile, Giovanni, Talerico, Michela, Talia, Eliezer Joseph Tassone, Thomas, Teatini, Elisabetta, Tombolini, Matteo, Traversa, Elia, Vettore, Alessandro, Vignal, Luca, Vilardi, Rosanna, Villani, Francesco, Vitale, Cicco, Sebastiano, D Abbondanza, Marco, Proietti, Marco, Zaccone, Vincenzo, Pes, Chiara, Caradio, Federica, Mattioli, Massimo, Piano, Salvatore, Marra, Alberto Maria, Nobili, Alessandro, Mannucci, Pier Mannuccio, Pietrangelo, Antonello, Sesti, Giorgio, Buzzetti, Elena, Salzano, Andrea, Cimellaro, Antonio, Antonio Cimellaro, Salvatore, Corrao, Mario, Barbagallo, Anna, Licata, Giuseppe, Montalto, Paolisso, Giuseppe, Rizzo, Maria Rosaria, and Cimellaro, Antonio - Giovani Internisti Società Italiana di Medicina Interna (GIS-SIMI) and of the REPOSI Investigators

Subjects
cardiovascular events, older patient, hypertension, antihypertensive drugs, older patients, survival, Clinical Biochemistry, antihypertensive drug, General Medicine, Biochemistry, cardiovascular event
Abstract

Background: Hypertension management in older patients represents a challenge, particularly when hospitalized. Objective: The objective of this study is to investigate the determinants and related outcomes of antihypertensive drug prescription in a cohort of older hospitalized patients. Methods: A total of 5671 patients from REPOSI (a prospective multicentre observational register of older Italian in-patients from internal medicine or geriatric wards) were considered; 4377 (77.2%) were hypertensive. Minimum treatment (MT) for hypertension was defined according to the 2018 ESC guidelines [an angiotensin-converting-enzyme-inhibitor (ACE-I) or an angiotensin-receptor-blocker (ARB) with a calcium-channel-blocker (CCB) and/or a thiazide diuretic; if >80 years old, an ACE-I or ARB or CCB or thiazide diuretic]. Determinants of MT discontinuation at discharge were assessed. Study outcomes were any cause rehospitalization/all cause death, all-cause death, cardiovascular (CV) hospitalization/death, CV death, non-CV death, evaluated according to the presence of MT at discharge. Results: Hypertensive patients were older than normotensives, with a more impaired functional status, higher burden of comorbidity and polypharmacy. A total of 2233 patients were on MT at admission, 1766 were on MT at discharge. Discontinuation of MT was associated with the presence of comorbidities (lower odds for diabetes, higher odds for chronic kidney disease and dementia). An adjusted multivariable logistic regression analysis showed that MT for hypertension at discharge was associated with lower risk of all-cause death, all-cause death/hospitalization, CV death, CV death/hospitalization and non-CV death. Conclusions: Guidelines-suggested MT for hypertension at discharge is associated with a lower risk of adverse clinical outcomes. Nevertheless, changes in antihypertensive treatment still occur in a significant proportion of older hospitalized patients.

Published
2023

9. Clinical features and outcomes of elderly hospitalised patients with chronic obstructive pulmonary disease, heart failure or both

Author

Crisafulli, Ernesto, Sartori, Giulia, Vianello, Alice, Busti, Fabiana, Nobili, Alessandro, Mannucci, Pier Mannuccio, Girelli, Domenico Investigators—Domenico Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene Mattioli (Azienda Ospedaliero Universitaria Careggi Firenze, SOD Medicina Interna Interdisciplinare), Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Michele, Zaccari, Massi- miliano Chiuch (Azienda Sanitaria Universitaria Integrata di Trieste, Clinica Medica Generale, e Terapia Medica), Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi (Azienda Ospedaliera della Pro- vincia di Lecco, Ospedale di Merate, Lecco, Medicina, Interna), Matteo, Pirro, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Alessia, Giotta, Mannarino (Azienda Ospedaliera Santa Maria della Misericordia, Massimo R., Perugia, Medicina, Interna, Angiologia Malattie da Arteriosclerosi), Domenico, Girelli, Fabiana, Busti, Giacomo Marchi (Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Medicina Generale e Malattie Aterotrombotiche, e Degenerative), Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica Cacioppo (Azienda Ospedaliera Universitaria Policlinico Giaccone Policlinico di Palermo, Palermo, Unità Operativa di Geriatria, e Lun- godegenza), Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Christiano, Argano, Civico, Federica Cavallaro (A. R. N. A. S., Cristina, Di, Benfratelli, Palermo, UOC Medicina Interna ad Indirizzo Geriatrico- Riabilitativo), Marco, Zoli, Maria Laura Mata- cena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Mattia, Brunori, Ilaria, Lazzari, Orsola-Malpighi, Angelo Simili (Azienda Ospe- daliera Universitaria Policlinico S., Bologna, Unità Operativa di Medicina Interna Zoli), Maria Domenica Cappellini, Gio- vanna Fabio, Margherita Migone De Amicis, Giacomo De Luca, Nata- lia Scaramellini, Valeria Di Stefano, Simona, Leoni, Sonia, Seghezzi, Alessandra Danuto Di Mauro, Diletta, Maira, Marta Mancarella (Fon- dazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Unità Operativa Medicina Interna IA), Tiziano, Lucchi, Paolo Dionigi Rossi, Marta, Clerici, Alessandra Danuta Di Mauro, Giulia, Bonini, Federica, Conti, Silvia, Prolo, Maddalena, Fabrizi, Miriana, Martelengo, Giulia, Vigani, Paola Nicolini (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Geriatria), Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Lavinia, Pitotti, Donatella, Padula, Valentina, Antoci, Ginevra Cambiè (IRCCS Policlinico San Matteo di Pavia, Pavia, Clinica Medica, I, Reparto, 11), Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Jacopo, Alberto, Federico Cattaneo (IRCCS Azienda Ospedaliera Universitaria San Martino-IST di Genova, Gen-, Ova, Clinica di Medicina Interna 2), Luigi, Anastasio, Lucia, Sofia, Maria Carbone (Ospedale Civile Jazzolino di Vibo Valentia, Vibo Val- entia, Medicina, Generale), Francesco, Cipollone, Maria Teresa Guag- nano, Ilaria, Rossi, Emanuele, Valeriani, Damiani, D’Ardes, Lucia, Esposito, Simona, Sestili, Annunziata, Ermanno Angelucci (Ospedale Clinicizzato SS., Chieti, Clinica, Medica), Gerardo, Mancuso, Daniela, Calipari, Mosè Bartone (Ospedale Giovanni Paolo II Lamezia Terme, Catanzaro, Unità Operativa Complessa Medicina Interna), Giuseppe, Delitala, Maria, Berria, Alessandro Delitala (Azienda ospedaliera- universitaria di Sassari, Maurizio, Muscaritoli, Ales- sio Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Gio- vanni Imbimbo (Policlinico Umberto, I, Sapienza Università di Roma, Medicina Interna, e Nutrizione Clinica Policlinico Umberto I), Giuseppe, Zuccalà, Gemelli, Gabriella D’Aurizio (Policlinico Universitario A., Roma, Roma, Unità Operativa Complessa Medicina d'Urgenza, e Pronto Soccorso)Giuseppe Romanelli, Alessandra, Marengoni, Andrea, Volpini, Daniela, Lucente, Francesca, Manzoni, Annalisa, Pirozzi, Alberto Zucchelli (Unità Operativa Complessa di Medicina I, a indirizzo geriatrico, Spedali, Civili, Montichiari, Brescia), Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Chiara Dell’Unto (Università Campus Bio- Medico, Roma, Medicina Clinica-Epatolo- gia), Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Alessandra, Bonfanti, Hajnalka, Szabo, Paolo, Mazzola, Andrea, Piazzoli, Gerardo, Maurizio Corsi (Università degli studi di Milano-Bicocca Ospedale S., Monza, Unità Operativa di Geri- atria), Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica Giofrè (Università degli Studi Magna Grecia, Policlinico Mater Domini, Cat-, Anzaro, Unità Operativa Complessa di Medicina Interna), Maria Grazia Serra, Maria Antonietta Bleve (Azienda Ospedaliera, Lecce, Unità Operativa Complessa Medicina), Antonio, Brucato, Teresa De Falco, Enrica, Negro, Martino, Brenna, Lucia, Trotta, Giovanni Lorenzo Squintani (ASST FatebenefratelliSacco, Maria Luisa Randi, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Francesco, Ratti, Chiara, Zurlo, Lorenzo, Cerruti, Elisabetta Cosi (Azienda Ospe- daliera Università di Padova, Padova, Clinica Medica I), Roberto Man- fredini, Benedetta, Boari, Alfredo De Giorgi, Ruana, Tiseo, Giulia Marta Viglione, Caterina Savriè (Azienda OspedalieraUniversitaria Sant'Anna, Ferrara, Unità Operativa Clinica Medica), Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Irene Di Meo (Azienda Ospedaliera Universitaria della Seconda Università degli Studi di Napoli, Napoli, VI Divisione di Medicina Interna, e Malattie Nutrizionali dell'Invecchiamento), Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, 13 Francesca Giulia Leoni, Valeria De Sando, Sara, Scarduelli, Michela, Cammarosano, Orsola-Malpighi, Ilenia Pareo (Azienda Ospedaliera Universitaria Poli- clinico S., Unità Operativa di Medicina Interna Borghi), Carlo, Sabbà, Francesco Saverio Vella, Patrizia Sup- pressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Ema- nuele Amoruso, Carlo, Custodero, Giuseppe, Re, Andrea, Schilardi, Francesca Loparco (Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Bari, Frugoni), Medicina Interna Universitaria C., Luigi, Fenoglio, Andrea, Falcetta, Alessia Valentina Giraudo, Salvatore D’Aniano (Azienda Sanitaria Ospedaliera Santa Croce, e Carle di Cuneo, Cuneo, Ademe, Medicina Interna), S. C., Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Felice Cinque (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, UOC Medicina Generale ad Indirizzo Metabolico), Flora, Peyvandi, Raffaella, Rossio, Colombo, Giulia, Pasquale, Agosti, Erica, Pagliaro, Eleonora Semproni (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Medicina Interna, 2, Emato- logia non tumorale, e Coagulopatie), Canetta, Ciro, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Christian Folli (Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Medicina Interna Alta Intensità di Cure), Francesco, Salerno, Giada Pallini (IRCCS Policlinico San Donato, e Università di Milano, San Donato Milanese, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Salam, Kassem, Luca Liberale (IRCCS Ospedale Policlinico San Martino, e Università di Genova, Genova, Clinica Medica, 1, Medicina Interna, e Specialità Mediche), Nicola Lucio Liberato, Tiziana Tognin (ASST di Pavia, UOSD Medicina Interna, Ospedale di Casorate Primo, Pavia), Francesco, Purrello, Antonino Di Pino, Salvatore Piro (Ospedale Garibaldi Nesima, Catania, Giorgia, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano Buf- felli, Camillo, Ferrandina, Francesca, Mazzeo, Elena, Spazzini, Giulia, Cono, Giulia Cesaroni (Ospedale Poliambulanza, Brescia, Medicina Interna, e Geriatria), Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura Sanino (Dipartimento di Scienze Mediche, Università di Torino, Città della Scienza, e della Salute, Torino, Medicina Interna, 2 Unità Indirizzo d'Urgenza), Franc- esco Violi, Ludovica Perri (Policlinico Umberto, I, Prima Clinica Medica), Guasti, Luigina, Rotunno, Francesca, Castiglioni, Luana, Maresca, ANDREA MARIA, Squizzato, Alessandro, Campiotti, Leonardo, Ales- sandra Grossi, Diprizio, ROBERTO DAVIDE, Francesco Dentali (Università degli Studi dell'Insubria, Ospedale di Circolo, e Fondazione Macchi, Varese, Elena, Medicina, e Geriatria), Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Elena, Bigi, Elisa, Pellegrini, Laura, Orlandi, Giulia, Dondi, Lucia Carulli (Università di Modena, e Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena, Ospedale Civile di Baggiovara, Unità Operativa di Geriatria), Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Aleandra, Scozzafava, Valentino, Condoleo, Tania, Falbo, Lidia, Colangelo, Marco Filice, Elvira Clausi (Università Geriatriche), Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vec- chio, Ilaria Benzoni (Dipartimento di Scienze Mediche, e Chirurgiche, Unità Operativa di Medicina Interna, Orsola-Malpighi, Università degli Studi di Bologna/ Azienda Ospedaliero- Universitaria S., Bologna), Andrea, Salvi, Roberto, Leonardi, Giampaolo Damiani (Spedali Civili di Brescia, Medicina Generale), U. O. 3a., Gianluca, Moroncini, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Monica, Ormas, Emanuele, Filippini, Devis, Benfaremo, Roberto Romiti (Clinica Medica, Azienda Ospedaliera Universitaria- Ospedali Riuniti di Ancona), Riccardo, Ghio, Anna Dal Col (Azienda Ospedaliera Università San Martino, Medicina, III), Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo Labbadia (Poli- clinico Umberto, I, SMSC03Medicina Interna F, e Malattie Meta- boliche dell'osso), Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita (Policlinico Campus Biomedico Roma, Medicina, Clinica), Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Emanuele, Samuele Pignataro (Azienda Ospedaliera Universitaria Poli- clinico – V., Catania, Dipartimento di Medicina), Francesca, Mete, Miriam Gino (Ospedale degli Infermi di Rivoli, Medicina Interna)Guido Moreo, Gloria Pina (Clinica San Carlo Casa di Cura Polispecialistica, Paderno, Dugnano, Unità Operativa di Medicina Generale Emilio Bernardelli), Alberto Balle- strero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Paolo, Setti, Chiara, Traversa, Camilla Scarsi (Clinica Di Medicina Interna ad Indirizzo Oncologico, Azienda Ospedaliera Università San Martino di Genova), Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella Gruden (Medicina Interna III, Giovanni Battista Molinette, Ospedale S., Torino), Franco, Berti, Giuseppe, Famularo, Patrizia Tarsitani (Azienda Ospedaliera San Camillo Forlanini, Medicina Interna II), Roberto, Castello, Michela Pasino (Ospedale Civile Maggiore Borgo Trento, Medicina Generale, e Sezione di Decisione Cli- nica), Marcello Giuseppe Maggio Gian Paolo Ceda, Simonetta Mor- ganti, Andrea, Artoni, Margherita Grossi (Azienda Ospedaliero Uni- versitaria di Parma, Clinica Geriatrica), U. O. C., Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giovanni, Paoletti, Francesca Losa (Policlinico Universitario Duilio Casula, Azienda Ospedaliero-Universitaria di Cagliari, Cagliari, Allergologia ed Immunologia Clinica), Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Angelo Rizzo (Azienda Ospe- daliera Universitaria Policlinico Paolo Giaccone, UOC di Medicina Interna), Francesco, Corica, Giorgio, Basile, Antonino Cata- lano, Federica, Bellone, Martino, Concetto Principato (Azienda Ospedaliera Universitaria Policlinico G., Messina, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella Caruso (Azienda Ospedaliera per l'Emergenza Cannizzaro, Clinica Medica Università di Catania), Patrizia, Mecocci, Carmelinda, Ruggiero, della Misericordia, Virginia Boccardi (Università degli Studi di Perugia-Azienda Ospedaliera S. M., Struttura Complessa di Geriatria), Tiziana, Meschi, Andrea, Ticinesi, Antonio Nouvenne (Azienda Ospedaliera Universitaria di Parma, Medicina Interna e Lungodegenza Critica), U. O., Pietro, Minuz, Luigi, Fondrieschi, Giandomen- ico Nigro Imperiale, Sarah Morellini (Azienda Ospedaliera Universi- taria Verona, Policlinico GB Rossi, Medicina Generale per lo Studio ed il Trattamento dell’Ipertensione Arteriosa), Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia Bellan (Azienda Ospedaliera Universitaria Maggiore della Carità, Medicina Interna 1), Roberto, Quadri, Erica, Larovere, Marco Novelli (Ospedale di Ciriè, Asl, To4, Emilio, Simeone, Rosa, Scurti, Fabio Tolloso (Ospedale Spirito Santo di Pescara, Geriatria), Roberto Tar- quini, Alice, Valoriani, Silvia, Dolenti, Giulia Vannini (Ospedale San Giuseppe, Empoli, USL Toscana Centro, Firenze, Medicina Interna I), Riccardo, Volpi, Pietro, Bocchi, Alessandro Vignali (Azienda Ospe- daliera Universitaria di Parma, Clinica, e Terapia Medica), Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia Aiello (Divisione di Medicina Interna, Multimedica, Ircss, Milano), Antonino Di Pino (Ospedale GaribaldiNesima, – Catania, Medicina Interna), U. O. C., Teresa, Salvatore, Lucio, Monaco, Vanvitelli, Carmen Ricozzi (Policlinico Università della Campania L., UOC Medicina Interna), Alberto, Pilotto, Ilaria, Indiano, Federica Gandolfo (Ente Ospe- daliero Ospedali Galliera Genova, SC Geriatria Dipartimento Cure Geriatriche, Ortogeriatria, e Riabilitazione)Franco Laghi Pasini, Pier Leopoldo Capecchi (Azienda Ospedaliera Universitaria Senese, Siena, Unità Operativa Complessa Medicina 2), Ranuccio, Nuti, Roberto Val- enti, Martina, Ruvio, Silvia, Cappelli, Alberto Palazzuoli (Azienda Ospedaliera Università Senese, Mauro Ber- nardi, Silvia Li Bassi, Luca, Santi, Giacomo Zaccherini (Azienda Ospe- daliera Policlinico Sant’Orsola-Malpighi, Semeiotica Medica Bernardi), Vittorio, Durante, Daniela, Tirotta, Giovanna Eusebi (Ospedale di Cattolica, Rimini, Marco, Cattaneo, Maria Valentina Amoruso, Paola, Fracasso, Cristina Fasolino (Azienda ospedaliera San Paolo, Moreno, Tresoldi, Enrica 13 Internal and Emergency Medicine Internal and Emergency Medicine Bozzolo, Sarah Damanti (IRCCS Ospedale San Raffaele, – Milano, Medicina Generale, e delle Cure Avanzate), Massimo, Porta, Miriam Gino (AOU Città della Salute e della Scienza di Torino, – Torino, and Medicina Interna, 1U).

Subjects
Hospital cure, Chronic obstructive pulmonary disease, Heart failure, Mortality, Multimorbidity, Prognosis
Published
2023

10. Probing hadronic interactions using the latest data measured by the Pierre Auger Observatory

Author

Caterina Trimarelli, Pedro Abreu, Marco Aglietta, Ingomar Allekotte, Kévin Almeida Cheminant, Alejandro Almela, Jaime Alvarez-Muniz, Juan Ammerman Yebra, Gioacchino Alex Anastasi, Luis A. Anchordoqui, Belén Andrada, Sofia Andringa, Carla Aramo, Paulo Ricardo Araújo Ferreira, Enrico Arnone, Juan Carlos Arteaga Velazquez, Hernán Gonzalo Asorey, Pedro Assis, Gualberto Avila, Emanuele Avocone, Alina Mihaela Badescu, Alena Bakalova, Alexandru Balaceanu, Felicia Barbato, Jose A. Bellido, Corinne Berat, Mario Edoardo Bertaina, Gopal Bhatta, Peter L. Biermann, Virginia Binet, Kathrin Bismark, Teresa Bister, Jonathan Biteau, Jiri Blazek, Carla Bleve, Johannes Blümer, Martina Bohacova, Denise Boncioli, Carla Bonifazi, Luan Bonneau Arbeletche, Nataliia Borodai, Jeffrey Brack, Thomas Bretz, P. Gabriel Brichetto Orchera, Florian Lukas Briechle, Peter Buchholz, Antonio Bueno, Stijn Buitink, Mario Buscemi, Max Büsken, Anthony Bwembya, Karen S. Caballero-Mora, Lorenzo Caccianiga, Ioana Caracas, Rossella Caruso, Antonella Castellina, Fernando Catalani, Gabriella Cataldi, Lorenzo Cazon, Marcos Cerda, Jose Augusto Chinellato, Jiří Chudoba, Ladislav Chytka, Roger W Clay, Agustín Cobos Cerutti, Roberta Colalillo, Alan Coleman, Maria Rita Coluccia, Rúben Conceição, Antonio Condorelli, Giovanni Consolati, Fernando Contreras, Fabio Convenga, Diego Correia dos Santos, Corbin Covault, Markus Cristinziani, Sergio Dasso, Kai Daumiller, Bruce R. Dawson, Jarryd A. Day, Rogerio M. de Almeida, Joaquin de Jesus, Sijbrand J. de Jong, João de Mello Neto, Ivan De Mitri, Jaime de Oliveira, Danelise de Oliveira Franco, Francesco de Palma, Vitor de Souza, Emanuele De Vito, Antonino Del Popolo, Olivier Deligny, Luca Deval, Armando di Matteo, Madalina Dobre, Carola Dobrigkeit, Juan Carlos D'Olivo, Luis Miguel Domingues Mendes, Rita Cassia dos Anjos, Maria Teresa Dova, Jan Ebr, Mohamed Eman, Ralph Engel, Italo Epicoco, Martin Erdmann, Carlos O. Escobar, Alberto Etchegoyen, Heino Falcke, John Farmer, Glennys R. Farrar, Anderson Campos Fauth, Norberto Fazzini, Fridtjof Feldbusch, Francesco Fenu, Brian Fick, Juan Manuel Figueira, Andrej Filipcic, Thomas Fitoussi, Tomáš Fodran, Toshihiro Fujii, Alan Fuster, Cristina Galea, Claudio Galelli, Beatriz García, Hartmut Gemmeke, Flavia Gesualdi, Alexandru Gherghel-Lascu, Piera Luisa Ghia, Ugo GIACCARI, Marco Giammarchi, Jonas Glombitza, Fabian Gobbi, Fernando Gollan, Geraldina Golup, Mariano Gómez Berisso, Primo F. Gómez Vitale, Juan Pablo Gongora, Juan Manuel González, Nicolas Martin Gonzalez, Isabel Goos, Dariusz Gora, Alessio Gorgi, Marvin Gottowik, Trent D. Grubb, Fausto Guarino, Germano Guedes, Eleonora Guido, Steffen Traugott Hahn, Petr Hamal, Matías Rolf Hampel, Patricia María Hansen, Diego Harari, Violet M. Harvey, Andreas Haungs, Thomas Hebbeker, Dieter Heck, Carlos Hojvat, Jörg R. Hörandel, Pavel Horvath, Miroslav Hrabovsky, Tim Huege, Antonio Insolia, Paula Gina Isar, Petr Janecek, Jeffrey A. Johnsen, Jakub Jurysek, Alex Kääpä, Karl-Heinz Kampert, Bianca Keilhauer, Abha Khakurdikar, Varada Varma Kizakke Covilakam, Hans Klages, Matthias Kleifges, Jonny Kleinfeller, Felix Knapp, Norbert Kunka, Bruno L. Lago, Niklas Langner, Marcelo Augusto Leigui de Oliveira, Vladimir Lenok, Antoine Letessier-Selvon, Isabelle Lhenry-Yvon, Domenico Lo Presti, Luis LOPES, Rebeca López, Lu Lu, Quentin Luce, Jon Paul Lundquist, Allan Machado Payeras, Giovanni Mancarella, Dusan Mandat, Bradley C. Manning, Julien Manshanden, Paul Mantsch, Sullivan Marafico, Federico Maria Mariani, Analisa Mariazzi, Ioana Maris, Giovanni Marsella, Daniele Martello, Sara Martinelli, Oscar Martínez Bravo, Miguel Alexandre Martins, Massimo Mastrodicasa, Hermann-Josef Mathes, James Matthews, Giorgio Matthiae, Eric William Mayotte, Sonja Mayotte, Peter Mazur, Gustavo Medina-Tanco, Diego Melo, Alexander Menshikov, Stanislav Michal, Maria Isabel Micheletti, Lino Miramonti, Silvia Mollerach, François Montanet, Leonel Morejon, Carlo Morello, Ana L. Müller, Katharine Mulrey, Roberto Mussa, Marco Stein Muzio, Wilson M. Namasaka, Alina Nasr-Esfahani, Lukas Nellen, Gabriela Nicora, Mihai Niculescu-Oglinzanu, Marcus Niechciol, Dave Nitz, Ian Norwood, Dalibor Nosek, Vladimír Novotný, Libor Nozka, Achille Nucita, Luis A. Nunez, Cainã Oliveira, Miroslav Palatka, Juan Pallotta, Gonzalo Parente, Alejandra Parra, Jannis Pawlowsky, Miroslav Pech, Jan Pękala, Rodrigo Pelayo, Edyvania Emily Pereira Martins, Johnnier Perez Armand, Carmina Pérez Bertolli, Lorenzo Perrone, Sergio Petrera, Camilla Petrucci, Tanguy Pierog, Mário Pimenta, Manuel Platino, Bjarni Pont, Mart Pothast, Paolo Privitera, Michael Prouza, Andrew Puyleart, Sven Querchfeld, Julian Rautenberg, Diego Ravignani, Maximilian Reininghaus, Jan Ridky, Felix Riehn, Markus Risse, Vincenzo Rizi, Washington Rodrigues de Carvalho, Jorge Rubén Rodriguez Rojo, Matías J. Roncoroni, Simone Rossoni, Markus Roth, Esteban Roulet, Adrian Rovero, Philip Ruehl, Alexandra Saftoiu, Mohit Saharan, Francesco Salamida, Humberto Ibarguen Salazar, Gaetano Salina, Jose Sanabria Gomez, Federico Andrés Sánchez, Edivaldo Moura Santos, Eva Santos, Fred Sarazin, Raul Sarmento, Ricardo Sato, Pierpaolo Savina, Christoph M. Schäfer, Viviana Scherini, Harald Schieler, Martin Schimassek, Michael Schimp, Felix Schlüter, David Schmidt, Olaf Scholten, Harm Schoorlemmer, Petr Schovanek, Frank G. Schröder, Josina Schulte, Tobias Schulz, Sergio J Sciutto, Marina Scornavacche, Alberto Segreto, Srijan Sehgal, Shima Ujjani Shivashankara, Guenter Sigl, Gaia Silli, Octavian Sima, Raluca Smau, Radomir Smida, Paul Sommers, Jorge F. Soriano, Ruben Squartini, Maximilian Stadelmaier, Denis Stanca, Samo Stanič, Jaroslaw Stasielak, Patrick Stassi, Maximilian Straub, Alexander Streich, Mauricio Suárez-Durán, Tristan Sudholz, Tiina Suomijarvi, A. Daniel Supanitsky, Zbigniew Szadkowski, Alex Tapia, Carla Taricco, Charles Timmermans, Olena Tkachenko, Petr Tobiska, Carlos J. Todero Peixoto, Bernardo Tomé, Zoé Torrès, Andres Travaini, Petr Travnicek, Matias Jorge Tueros, Ralf Ulrich, Michael Unger, Lukáš Vaclavek, Martin Vacula, Jose F. Valdés Galicia, Laura Valore, Enrique Varela, Adriana Vásquez-Ramírez, Darko Veberic, Cynthia Ventura, Indira D. Vergara Quispe, Valerio Verzi, Jakub Vicha, Jacco Vink, Serguei Vorobiov, Hernan Wahlberg, Clara Keiko Oliveira Watanabe, Alan Watson, Andreas Weindl, Lawrence Wiencke, Henryk Wilczyński, David Wittkowski, Brian Wundheiler, Alexey Yushkov, Orazio Zapparrata, Enrique Zas, Danilo Zavrtanik, Marko Zavrtanik, and Lukas Zehrer

Published
2022

11. Hyperglycemia at admission, comorbidities, and in-hospital mortality in elderly patients hospitalized in internal medicine wards: data from the RePoSI Registry

Author

Salvatore, Corrao, Alessandro, Nobili, Giuseppe, Natoli, Pier Mannuccio Mannucci, Francesco, Perticone, Antonello, Pietrangelo, Christiano, Argano, Giuseppe, Licata, Francesco, Violi, Gino Roberto Corazza, Alessandra, Marengoni, Francesco, Salerno, Matteo, Cesari, Mauro, Tettamanti, Luca, Pasina, Carlotta, Franchi, Laura, Cortesi, Gabriella, Miglio, Ilaria, Ardoino, Alessio, Novella, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Cenci, Caterina, Gianni, Biolo, Michela, Zanetti, Martina, Guadagni, Michele, Zaccari, Massimiliano, Chiuch, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Mauro, Bernardi, Silvia Li Bassi, Luca, Santi, Giacomo, Zaccherini, Graziana, Lupattelli, Elmo, Mannarino, Vanessa, Bianconi, Francesco, Paciullo, Riccardo, Alcidi, Ranuccio, Nuti, Roberto, Valenti, Martina, Ruvio, Silvia, Cappelli, Alberto, Palazzuoli, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Floriana, Cocita, Vincenza, Beneduce, Lidia, Plances, Salvatore, Mularo, Massimo, Raspanti, Marco, Zoli, Ilaria, Lazzari, Mattia, Brunori, Elisa, Fabbri, Donatella, Magalotti, Raffaella, Arnò, Franco Laghi Pasini, Pier Leopoldo Capecchi, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Diletta, Maira, Valeria Di Stefano, Giovanna, Fabio, Sonia, Seghezzi, Marta, Mancarella, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Federica, Conti, Giulia, Bonini, Barbara Brignolo Ottolini, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Giovanni, Murialdo, Alessio, Marra, Federico, Cattaneo, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Maria Beatrice Secchi, Davide, Ghelfi, Luigi, Anastasio, Lucia, Sofia, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Emanuele, Valeriani, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Chiara, Pes, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Giuseppe, Zuccalà, Gabriella, D'Aurizio, Giuseppe, Romanelli, Alberto, Zucchelli, Francesca, Manzoni, Andrea, Volpini, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Chiara, Dell'Unto, Giorgio, Annoni, Maurizio, Corsi, Giuseppe, Bellelli, Sara, Zazzetta, Paolo, Mazzola, Hajnalka, Szabo, Alessandra, Bonfanti, Franco, Arturi, Elena, Succurro, Mariangela, Rubino, Bruno, Tassone, Giorgio, Sesti, Maria Grazia Serra, Maria Antonietta Bleve, Laura, Gasbarrone, Maria Rosaria Sajeva, Antonio, Brucato, Silvia, Ghidoni, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Elisabetta, Cosi, Paolo, Scarinzi, Annalisa, Amabile, Elisabetta, Omenetto, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Boari, Benedetta, DE GIORGI, Alfredo, Tiseo, Ruana, DE GIORGIO, Roberto, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Andrea, Schilardi, Francesca, Loparco, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Luigi, Fenoglio, Andrea, Falcetta, Christian, Bracco, Anna, L Fracanzani Silvia Fargion, Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Barbara, Ferrari, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Christian, Folli, Giuliana, Ceriani, Giada, Pallini, Franco, Dallegri, Luciano, Ottonello, Luca, Liberale, Lara, Caserza, Kassem, Salam, Nicola Lucio Liberato, Tiziana, Tognin, Giovanni Battista Bianchi, Sabrina, Giaquinto, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Elena, Spazzini, Camillo, Ferrandina, Giuseppe, Montrucchio, Paolo, Petitti, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Raffaella, Salmi, Piergiorgio, Gaudenzi, Ludovica, Perri, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Giulia, Dondi, Elisa, Pellegrini, Lucia, Carulli, Matteo, Galassi, Yasmine, Grassi, Maria, Perticone, Rosa, Battaglia, Marco, Filice, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara Del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Armando, Gabrielli, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Samuele, Pignataro, Alfio, Gennaro, Julien, Blanco, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Antonio, Cittadini, Carlo, Vigorito, Michele, Arcopinto, Andrea, Salzano, Emanuele, Bobbio, Alberto Maria Marra, Domenico, Sirico, Guido, Moreo, Francesca, Gasparini, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Giuseppe, Scattolin, Sergio, Martinelli, Mauro, Turrin, Leonardo, Sechi, Cristina, Catena, Gianluca, Colussi, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Stefano Del Giacco, Davide, Firinu, Francesca, Losa, Giovanni, Paoletti, Giulia, Costanzo, Giuseppe, Montalto, Anna, Licata, Valentina, Malerba, Filippo Alessandro Montalto, Antonino, Lasco, Giorgio, Basile, Antonino, Catalano, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Fulvio, Lauretani, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Alberto, Tedeschi, Lucia, Trotta, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Mara, Cattaneo, Federico, Napoli., Corrao S, Nobili A, Natoli G, Mannucci PM, Perticone F, Pietrangelo A, Argano C, REPOSI Investigator, Borghi C, Corrao S., Nobili A., Natoli G., Mannucci P.M., Perticone F., Pietrangelo A., Argano C., Licata G., Violi F., Corazza G.R., Marengoni A., Salerno F., Cesari M., Tettamanti M., Pasina L., Franchi C., Cortesi L., Miglio G., Ardoino I., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Caterina C., Biolo G., Zanetti M., Guadagni M., Zaccari M., Chiuch M., Vanoli M., Grignani G., Pulixi E.A., Bernardi M., Bassi S.L., Santi L., Zaccherini G., Lupattelli G., Mannarino E., Bianconi V., Paciullo F., Alcidi R., Nuti R., Valenti R., Ruvio M., Cappelli S., Palazzuoli A., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Cocita F., Beneduce V., Plances L., Mularo S., Raspanti M., Zoli M., Lazzari I., Brunori M., Fabbri E., Magalotti D., Arno R., Pasini F.L., Capecchi P.L., Palasciano G., Modeo M.E., Di Gennaro C., Cappellini M.D., Maira D., Di Stefano V., Fabio G., Seghezzi S., Mancarella M., De Amicis M.M., De Luca G., Scaramellini N., Rossi P.D., Damanti S., Clerici M., Conti F., Bonini G., Ottolini B.B., Di Sabatino A., Miceli E., Lenti M.V., Pisati M., Dominioni C.C., Murialdo G., Marra A., Cattaneo F., Pontremoli R., Beccati V., Nobili G., Secchi M.B., Ghelfi D., Anastasio L., Sofia L., Carbone M., Cipollone F., Guagnano M.T., Valeriani E., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Pes C., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Zuccala G., D'Aurizio G., Romanelli G., Zucchelli A., Manzoni F., Volpini A., Picardi A., Gentilucci U.V., Gallo P., Dell'Unto C., Annoni G., Corsi M., Bellelli G., Zazzetta S., Mazzola P., Szabo H., Bonfanti A., Arturi F., Succurro E., Rubino M., Tassone B., Sesti G., Serra M.G., Bleve M.A., Gasbarrone L., Sajeva M.R., Brucato A., Ghidoni S., Fabris F., Bertozzi I., Bogoni G., Rabuini M.V., Cosi E., Scarinzi P., Amabile A., Omenetto E., Prandini T., Manfredini R., Fabbian F., Boari B., De Giorgi A., Tiseo R., De Giorgio R., Paolisso G., Rizzo M.R., Borghi C., Strocchi E., Ianniello E., Soldati M., Sabba C., Vella F.S., Suppressa P., Schilardi A., Loparco F., De Vincenzo G.M., Comitangelo A., Amoruso E., Fenoglio L., Falcetta A., Bracco C., Fargion A.L.F.S., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Ferrari B., Colombo G., Agosti P., Monzani V., Savojardo V., Folli C., Ceriani G., Pallini G., Dallegri F., Ottonello L., Liberale L., Caserza L., Salam K., Liberato N.L., Tognin T., Bianchi G.B., Giaquinto S., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Spazzini E., Ferrandina C., Montrucchio G., Petitti P., Peasso P., Favale E., Poletto C., Salmi R., Gaudenzi P., Perri L., Landolfi R., Montalto M., Mirijello A., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Bertolotti M., Mussi C., Lancellotti G., Libbra M.V., Dondi G., Pellegrini E., Carulli L., Galassi M., Grassi Y., Perticone M., Battaglia R., FIlice M., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Gabrielli A., Mattioli M., Martino G.P., Biondi L., Pettinari P., Ghio R., Col A.D., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M.E., Castellino P., Zanoli L., Pignataro S., Gennaro A., Blanco J., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Cittadini A., Vigorito C., Arcopinto M., Salzano A., Bobbio E., Marra A.M., Sirico D., Moreo G., Gasparini F., Prolo S., Pina G., Ballestrero A., Ferrando F., Berra S., Dassi S., Nava M.C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Scattolin G., Martinelli S., Turrin M., Sechi L., Catena C., Colussi G., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G.P., Maggio M.G., Morganti S., Artoni A., Del Giacco S., Firinu D., Losa F., Paoletti G., Costanzo G., Montalto G., Licata A., Malerba V., Montalto F.A., Lasco A., Basile G., Catalano A., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., La Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Lauretani F., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Pirisi M., Fra G.P., Sola D., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Tedeschi A., Trotta L., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Cattaneo M., Napoli F., Corrao, S., Nobili, A., Natoli, G., Mannucci, P. M., Perticone, F., Pietrangelo, A., Argano, C., Licata, G., Violi, F., Corazza, G. R., Marengoni, A., Salerno, F., Cesari, M., Tettamanti, M., Pasina, L., Franchi, C., Cortesi, L., Miglio, G., Ardoino, I., Novella, A., Prisco, D., Silvestri, E., Emmi, G., Bettiol, A., Caterina, C., Biolo, G., Zanetti, M., Guadagni, M., Zaccari, M., Chiuch, M., Vanoli, M., Grignani, G., Pulixi, E. A., Bernardi, M., Bassi, S. L., Santi, L., Zaccherini, G., Lupattelli, G., Mannarino, E., Bianconi, V., Paciullo, F., Alcidi, R., Nuti, R., Valenti, R., Ruvio, M., Cappelli, S., Palazzuoli, A., Girelli, D., Busti, F., Marchi, G., Barbagallo, M., Dominguez, L., Cocita, F., Beneduce, V., Plances, L., Mularo, S., Raspanti, M., Zoli, M., Lazzari, I., Brunori, M., Fabbri, E., Magalotti, D., Arno, R., Pasini, F. L., Capecchi, P. L., Palasciano, G., Modeo, M. E., Di Gennaro, C., Cappellini, M. D., Maira, D., Di Stefano, V., Fabio, G., Seghezzi, S., Mancarella, M., De Amicis, M. M., De Luca, G., Scaramellini, N., Rossi, P. D., Damanti, S., Clerici, M., Conti, F., Bonini, G., Ottolini, B. B., Di Sabatino, A., Miceli, E., Lenti, M. V., Pisati, M., Dominioni, C. C., Murialdo, G., Marra, A., Cattaneo, F., Pontremoli, R., Beccati, V., Nobili, G., Secchi, M. B., Ghelfi, D., Anastasio, L., Sofia, L., Carbone, M., Cipollone, F., Guagnano, M. T., Valeriani, E., Rossi, I., Mancuso, G., Calipari, D., Bartone, M., Delitala, G., Berria, M., Pes, C., Delitala, A., Muscaritoli, M., Molfino, A., Petrillo, E., Zuccala, G., D'Aurizio, G., Romanelli, G., Zucchelli, A., Manzoni, F., Volpini, A., Picardi, A., Gentilucci, U. V., Gallo, P., Dell'Unto, C., Annoni, G., Corsi, M., Bellelli, G., Zazzetta, S., Mazzola, P., Szabo, H., Bonfanti, A., Arturi, F., Succurro, E., Rubino, M., Tassone, B., Sesti, G., Serra, M. G., Bleve, M. A., Gasbarrone, L., Sajeva, M. R., Brucato, A., Ghidoni, S., Fabris, F., Bertozzi, I., Bogoni, G., Rabuini, M. V., Cosi, E., Scarinzi, P., Amabile, A., Omenetto, E., Prandini, T., Manfredini, R., Fabbian, F., Boari, B., De Giorgi, A., Tiseo, R., De Giorgio, R., Paolisso, G., Rizzo, M. R., Borghi, C., Strocchi, E., Ianniello, E., Soldati, M., Sabba, C., Vella, F. S., Suppressa, P., Schilardi, A., Loparco, F., De Vincenzo, G. M., Comitangelo, A., Amoruso, E., Fenoglio, L., Falcetta, A., Bracco, C., Fargion, A. L. F. S., Tiraboschi, S., Cespiati, A., Oberti, G., Sigon, G., Peyvandi, F., Rossio, R., Ferrari, B., Colombo, G., Agosti, P., Monzani, V., Savojardo, V., Folli, C., Ceriani, G., Pallini, G., Dallegri, F., Ottonello, L., Liberale, L., Caserza, L., Salam, K., Liberato, N. L., Tognin, T., Bianchi, G. B., Giaquinto, S., Purrello, F., Di Pino, A., Piro, S., Rozzini, R., Falanga, L., Spazzini, E., Ferrandina, C., Montrucchio, G., Petitti, P., Peasso, P., Favale, E., Poletto, C., Salmi, R., Gaudenzi, P., Perri, L., Landolfi, R., Montalto, M., Mirijello, A., Guasti, L., Castiglioni, L., Maresca, A., Squizzato, A., Campiotti, L., Grossi, A., Bertolotti, M., Mussi, C., Lancellotti, G., Libbra, M. V., Dondi, G., Pellegrini, E., Carulli, L., Galassi, M., Grassi, Y., Perticone, M., Battaglia, R., Filice, M., Maio, R., Stanghellini, V., Ruggeri, E., del Vecchio, S., Salvi, A., Leonardi, R., Damiani, G., Capeci, W., Gabrielli, A., Mattioli, M., Martino, G. P., Biondi, L., Pettinari, P., Ghio, R., Col, A. D., Minisola, S., Colangelo, L., Cilli, M., Labbadia, G., Afeltra, A., Marigliano, B., Pipita, M. E., Castellino, P., Zanoli, L., Pignataro, S., Gennaro, A., Blanco, J., Saracco, V., Fogliati, M., Bussolino, C., Mete, F., Gino, M., Cittadini, A., Vigorito, C., Arcopinto, M., Salzano, A., Bobbio, E., Marra, A. M., Sirico, D., Moreo, G., Gasparini, F., Prolo, S., Pina, G., Ballestrero, A., Ferrando, F., Berra, S., Dassi, S., Nava, M. C., Graziella, B., Baldassarre, S., Fragapani, S., Gruden, G., Galanti, G., Mascherini, G., Petri, C., Stefani, L., Girino, M., Piccinelli, V., Nasso, F., Gioffre, V., Pasquale, M., Scattolin, G., Martinelli, S., Turrin, M., Sechi, L., Catena, C., Colussi, G., Passariello, N., Rinaldi, L., Berti, F., Famularo, G., Tarsitani, P., Castello, R., Pasino, M., Ceda, G. P., Maggio, M. G., Morganti, S., Artoni, A., Del Giacco, S., Firinu, D., Losa, F., Paoletti, G., Costanzo, G., Montalto, G., Licata, A., Malerba, V., Montalto, F. A., Lasco, A., Basile, G., Catalano, A., Malatino, L., Stancanelli, B., Terranova, V., Di Marca, S., Di Quattro, R., La Malfa, L., Caruso, R., Mecocci, P., Ruggiero, C., Boccardi, V., Meschi, T., Lauretani, F., Ticinesi, A., Nouvenne, A., Minuz, P., Fondrieschi, L., Pirisi, M., Fra, G. P., Sola, D., Porta, M., Riva, P., Quadri, R., Larovere, E., Novelli, M., Scanzi, G., Mengoli, C., Provini, S., Ricevuti, L., Simeone, E., Scurti, R., Tolloso, F., Tarquini, R., Valoriani, A., Dolenti, S., Vannini, G., Tedeschi, A., Trotta, L., Volpi, R., Bocchi, P., Vignali, A., Harari, S., Lonati, C., Cattaneo, M., Napoli, F., Corrao, S, Nobili, A, Natoli, G, Mannucci, P, Perticone, F, Pietrangelo, A, Argano, C, Licata, G, Violi, F, Corazza, G, Marengoni, A, Salerno, F, Cesari, M, Tettamanti, M, Pasina, L, Franchi, C, Cortesi, L, Miglio, G, Ardoino, I, Novella, A, Prisco, D, Silvestri, E, Emmi, G, Bettiol, A, Caterina, C, Biolo, G, Zanetti, M, Guadagni, M, Zaccari, M, Chiuch, M, Vanoli, M, Grignani, G, Pulixi, E, Bernardi, M, Bassi, S, Santi, L, Zaccherini, G, Lupattelli, G, Mannarino, E, Bianconi, V, Paciullo, F, Alcidi, R, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Palazzuoli, A, Girelli, D, Busti, F, Marchi, G, Barbagallo, M, Dominguez, L, Cocita, F, Beneduce, V, Plances, L, Mularo, S, Raspanti, M, Zoli, M, Lazzari, I, Brunori, M, Fabbri, E, Magalotti, D, Arno, R, Pasini, F, Capecchi, P, Palasciano, G, Modeo, M, Di Gennaro, C, Cappellini, M, Maira, D, Di Stefano, V, Fabio, G, Seghezzi, S, Mancarella, M, De Amicis, M, De Luca, G, Scaramellini, N, Rossi, P, Damanti, S, Clerici, M, Conti, F, Bonini, G, Ottolini, B, Di Sabatino, A, Miceli, E, Lenti, M, Pisati, M, Dominioni, C, Murialdo, G, Marra, A, Cattaneo, F, Pontremoli, R, Beccati, V, Nobili, G, Secchi, M, Ghelfi, D, Anastasio, L, Sofia, L, Carbone, M, Cipollone, F, Guagnano, M, Valeriani, E, Rossi, I, Mancuso, G, Calipari, D, Bartone, M, Delitala, G, Berria, M, Pes, C, Delitala, A, Muscaritoli, M, Molfino, A, Petrillo, E, Zuccala, G, D'Aurizio, G, Romanelli, G, Zucchelli, A, Manzoni, F, Volpini, A, Picardi, A, Gentilucci, U, Gallo, P, Dell'Unto, C, Annoni, G, Corsi, M, Bellelli, G, Zazzetta, S, Mazzola, P, Szabo, H, Bonfanti, A, Arturi, F, Succurro, E, Rubino, M, Tassone, B, Sesti, G, Serra, M, Bleve, M, Gasbarrone, L, Sajeva, M, Brucato, A, Ghidoni, S, Fabris, F, Bertozzi, I, Bogoni, G, Rabuini, M, Cosi, E, Scarinzi, P, Amabile, A, Omenetto, E, Prandini, T, Manfredini, R, Fabbian, F, Boari, B, De Giorgi, A, Tiseo, R, De Giorgio, R, Paolisso, G, Rizzo, M, Borghi, C, Strocchi, E, Ianniello, E, Soldati, M, Sabba, C, Vella, F, Suppressa, P, Schilardi, A, Loparco, F, De Vincenzo, G, Comitangelo, A, Amoruso, E, Fenoglio, L, Falcetta, A, Bracco, C, Fargion, A, Tiraboschi, S, Cespiati, A, Oberti, G, Sigon, G, Peyvandi, F, Rossio, R, Ferrari, B, Colombo, G, Agosti, P, Monzani, V, Savojardo, V, Folli, C, Ceriani, G, Pallini, G, Dallegri, F, Ottonello, L, Liberale, L, Caserza, L, Salam, K, Liberato, N, Tognin, T, Bianchi, G, Giaquinto, S, Purrello, F, Di Pino, A, Piro, S, Rozzini, R, Falanga, L, Spazzini, E, Ferrandina, C, Montrucchio, G, Petitti, P, Peasso, P, Favale, E, Poletto, C, Salmi, R, Gaudenzi, P, Perri, L, Landolfi, R, Montalto, M, Mirijello, A, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Campiotti, L, Grossi, A, Bertolotti, M, Mussi, C, Lancellotti, G, Libbra, M, Dondi, G, Pellegrini, E, Carulli, L, Galassi, M, Grassi, Y, Perticone, M, Battaglia, R, Filice, M, Maio, R, Stanghellini, V, Ruggeri, E, del Vecchio, S, Salvi, A, Leonardi, R, Damiani, G, Capeci, W, Gabrielli, A, Mattioli, M, Martino, G, Biondi, L, Pettinari, P, Ghio, R, Col, A, Minisola, S, Colangelo, L, Cilli, M, Labbadia, G, Afeltra, A, Marigliano, B, Pipita, M, Castellino, P, Zanoli, L, Pignataro, S, Gennaro, A, Blanco, J, Saracco, V, Fogliati, M, Bussolino, C, Mete, F, Gino, M, Cittadini, A, Vigorito, C, Arcopinto, M, Salzano, A, Bobbio, E, Sirico, D, Moreo, G, Gasparini, F, Prolo, S, Pina, G, Ballestrero, A, Ferrando, F, Berra, S, Dassi, S, Nava, M, Graziella, B, Baldassarre, S, Fragapani, S, Gruden, G, Galanti, G, Mascherini, G, Petri, C, Stefani, L, Girino, M, Piccinelli, V, Nasso, F, Gioffre, V, Pasquale, M, Scattolin, G, Martinelli, S, Turrin, M, Sechi, L, Catena, C, Colussi, G, Passariello, N, Rinaldi, L, Berti, F, Famularo, G, Tarsitani, P, Castello, R, Pasino, M, Ceda, G, Maggio, M, Morganti, S, Artoni, A, Del Giacco, S, Firinu, D, Losa, F, Paoletti, G, Costanzo, G, Montalto, G, Licata, A, Malerba, V, Montalto, F, Lasco, A, Basile, G, Catalano, A, Malatino, L, Stancanelli, B, Terranova, V, Di Marca, S, Di Quattro, R, La Malfa, L, Caruso, R, Mecocci, P, Ruggiero, C, Boccardi, V, Meschi, T, Lauretani, F, Ticinesi, A, Nouvenne, A, Minuz, P, Fondrieschi, L, Pirisi, M, Fra, G, Sola, D, Porta, M, Riva, P, Quadri, R, Larovere, E, Novelli, M, Scanzi, G, Mengoli, C, Provini, S, Ricevuti, L, Simeone, E, Scurti, R, Tolloso, F, Tarquini, R, Valoriani, A, Dolenti, S, Vannini, G, Tedeschi, A, Trotta, L, Volpi, R, Bocchi, P, Vignali, A, Harari, S, Lonati, C, Cattaneo, M, and Napoli, F

Subjects
Registrie, Male, Comorbidity, Diabetes, Disability, Elderly, Hyperglycemia, Mortality, Aged, Aged, 80 and over, Female, Hospital Mortality, Hospitals, Humans, Internal Medicine, Registries, Hospitalization, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Socio-culturale, Renal function, 030204 cardiovascular system & hematology, Diabete, Hospital, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Rating scale, Internal medicine, Diabetes mellitus, 80 and over, medicine, LS4_4, 030212 general & internal medicine, Class III obesity, business.industry, Mortality rate, Comorbidity, Diabetes, Disability, Elderly, Hyperglycemia, Mortality, General Medicine, medicine.disease, Mood disorders, Geriatric Depression Scale, Original Article, business, Human
Abstract

Aims The association between hyperglycemia at hospital admission and relevant short- and long-term outcomes in elderly population is known. We assessed the effects on mortality of hyperglycemia, disability, and multimorbidity at admission in internal medicine ward in patients aged ≥ 65 years. Methods Data were collected from an active register of 102 internal medicine and geriatric wards in Italy (RePoSi project). Patients were recruited during four index weeks of a year. Socio-demographic data, reason for hospitalization, diagnoses, treatment, severity and comorbidity indexes (Cumulative Illness rating Scale CIRS-SI and CIRS-CI), renal function, functional (Barthel Index), and cognitive status (Short Blessed Test) and mood disorders (Geriatric Depression Scale) were recorded. Mortality rates were assessed in hospital 3 and 12 months after discharge. Results Of the 4714 elderly patients hospitalized, 361 had a glycemia level ≥ 250 mg/dL at admission. Compared to subjects with lower glycemia level, patients with glycemia ≥ 250 mg/dL showed higher rates of male sex, smoke and class III obesity. These patients had a significantly lower Barthel Index (p = 0.0249), higher CIRS-SI and CIRS-CI scores (p = 0.0025 and p = 0.0013, respectively), and took more drugs. In-hospital mortality rate was 9.2% and 5.1% in subjects with glycemia ≥ 250 and p = 0.0010). Regression analysis showed a strong association between in-hospital death and glycemia ≥ 250 mg/dL (OR 2.07; [95% CI 1.34–3.19]), Barthel Index ≤ 40 (3.28[2.44–4.42]), CIRS-SI (1.87[1.27–2.77]), and male sex (1.54[1.16–2.03]). Conclusions The stronger predictors of in-hospital mortality for older patients admitted in general wards were glycemia level ≥ 250 mg/dL, Barthel Index ≤ 40, CIRS-SI, and male sex.

Published
2021

12. Impact of Diabetes Mellitus and Its Comorbidities on Elderly Patients Hospitalized in Internal Medicine Wards: Data from the RePoSi Registry

Author

Christiano, Argano, Giuseppe, Natoli, Salvatore, Mularo, Alessandro, Nobili, Marika Lo Monaco, Pier Mannuccio Mannucci, Francesco, Perticone, Antonello, Pietrangelo, Salvatore, Corrao, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Massimo, Raspanti, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Matteo, Cesari, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Alessandra, Marengoni, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio, Brucato, Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, DE GIORGI, Alfredo, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Francesco, Salerno, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Francesco, Violi, Ludovica, Perri, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Silvia, Ghidoni, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, Federica, Gandolfo., Argano C., Natoli G., Mularo S., Nobili A., Lo Monaco M., Mannucci P.M., Perticone F., Pietrangelo A., and Corrao S.

Subjects
Leadership and Management, 1-year mortality, cancer, comorbidities, diabetes, heart rate, in-hospital mortality, male sex, Heart rate, Socio-culturale, Health Informatics, comorbidities, Article, Comorbidities, Health Information Management, diabetes, heart rate, cancer, male sex, in-hospital mortality, 1-year mortality, Cancer, Diabetes, In-hospital mortality, Male sex, LS4_4, Health Policy, Medicine, 1-year mortality, Cancer, Comorbidities, Diabetes, Heart rate, In-hospital mortality, Male
Abstract

Background: Currently, diabetes represents the seventh leading cause of death worldwide, with a significant economic burden. The number and severity of comorbidities increase with age, and are identified as important determinants that influence the prognosis. We aimed to investigate comorbidities and outcomes in a cohort of hospitalized elderly patients affected by diabetes. Methods: In this observational study, we retrospectively analyzed data collected from the REgistro dei pazienti per lo studio delle POlipatologie e politerapie in reparti della rete Simi (RePoSi) registry. Socio-demographic, clinical characteristics, and laboratory findings were considered. The association between variables and in-hospital and 1-year follow-up were analyzed. Results: Among 4708 in-patients, 1378 (29.3%) had a diagnosis of diabetes. Patients with diabetes had more previous hospitalization, a clinically significant disability, and more need for a urinary catheter in comparison with subjects without diabetes. Patients affected by diabetes took more drugs, both at admission, at in-hospital stay, at discharge, and at 1-year follow-up. Thirty-five comorbidities were more frequent in patients with diabetes, and the first five were hypertension (57.1%), ischemic heart disease (31.4%), chronic renal failure (28.8%), atrial fibrillation (25.6%), and chronic obstructive pulmonary disease (22.7%). Heart rate was an independent predictor of in-hospital mortality. At 1-year follow-up, cancer and male sex were strongly independently associated with mortality. Conclusions: Our findings showed the severity of the impact of diabetes and its comorbidities in the real life of internal medicine and geriatric wards, and provide data to be used for a better tailored management of elderly in-patients with diabetes.

Published
2022

13. Relation between drug therapy-based comorbidity indices, Charlson's comorbidity index, polypharmacy and mortality in three samples of older adults

Author

Alessio, Novella, Chiara, Elli, Mauro, Tettamanti, Alessandro, Nobili, Aladar, Ianes, Pier Mannuccio Mannucci, Luca, Pasina, Carlotta, Franchi, Gualberto, Gussoni, Stefano, Bonassi, Antonella, Valerio, Federica, Mammarella, Codjo Djignefa Djade, Raffaella, Rossio, Barbara, Ferrari, Daniela, Mari, Marco, Ferretti, Francesco, Salerno, Alessio, Conca, Antonino, Tuttolomondo, Anna, Cirrincione, Antonio, Pinto, Antonio, Cherubini, Giuseppina, Dell’Aquila, Roberto, Bernabei, Graziano, Onder, Michele, Ciaburri, Dario, Manfellotto, Irene, Caridi, Enzo, Lancia, Alessandra, Forgione, Concetta, Donato, Serra Maria Grazia, Luigi, Lusiani, Bullo, Cristina, Brocco, Stefano, Pedretti, Giovanni, Pattacini, Corrado, Francesco, Violi, Ludovica, Perri, Luigi Di Cioccio, Carlo Di Meo, Laura, Minchella, Moira, Ceci, Alberto, Ferrari, Salvatore, Foderaro, Antonio, Brucato, Anna, Valenti, Silvia, Ghidoni, Renzo, Rozzini, Lina, Falanga, Alessandra, Marengoni, Simona, Ghibelli, Chiara, Mussi, Maria Alice Ferri, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Christiano, Argano, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Matteo, Cesari, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Lucia, Sofia, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Antonietta Bleve, Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, Alfredo De Giorgi, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Marco, Bertolotti, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, and Federica, Gandolfo.

Subjects
Aging, Comorbidity indices, Health (social science), Socio-culturale, Multimorbidity, Comorbidity, Chronic disease, Hospitalization, Italy, Older adults, Chronic disease, Comorbidity indices, Excessive polypharmacy, Mortality, Multimorbidity, Older adults, Excessive polypharmacy, Polypharmacy, Humans, LS4_4, Geriatrics and Gerontology, Mortality, Gerontology, Aged
Abstract

Comorbidity indexes were designed in order to measure how the disease burden of a patient is related to different clinical outcomes such as mortality, especially in older and intensively treated people. Charlson's Comorbidity Index (CCI) is the most widely used rating system, based on diagnoses, but when this information is not available therapy-based comorbidity indices (TBCI) are an alternative: among them, Drug Derived Complexity Index (DDCI), Medicines Comorbidity Index (MCI), and Chronic Disease Score (CDS) are available.This study assessed the predictive power for 1-year mortality of these comorbidity indices and polypharmacy.Survival analysis and Receiver Operating Characteristic (ROC) analysis were conducted on three Italian cohorts: 2,389 nursing home residents (Korian), 4,765 and 633 older adults admitted acutely to geriatric or internal medicine wards (REPOSI and ELICADHE).Cox's regression indicated that the highest levels of the CCI are associated with an increment of 1-year mortality risk as compared to null score for all the three samples. DDCI and excessive polypharmacy gave similar results but MCI and CDS were not always statistically significant. The predictive power with the ROC curve of each comorbidity index was poor and similar in all settings.On the whole, comorbidity indices did not perform well in our three settings, although the highest level of each index was associated with higher mortality.

Published
2022

14. Extraction of the Muon Signals Recorded with the Surface Detector of the Pierre Auger Observatory Using Recurrent Neural Networks

Author

Jose Chinellato, Marvin Gottowik, Dariusz Gora, Eric Mayotte, A. Gorgi, M. Gómez Berisso, Alan Coleman, S. J. Saffi, Ioana Caracas, R. C. Shellard, R.J. Barreira Luz, Miroslav Pech, M. Pothast, Pavel Horvath, A. Letessier-Selvon, Mario Buscemi, G. De Mauro, A. Tapia, Jörg R. Hörandel, I. Lhenry-Yvon, P. Ruehl, L. Valore, H. Gemmeke, Lorenzo Cazon, C. Pérez Bertolli, M. Suárez-Durán, M. Unger, E. M. Santos, Sullivan Marafico, Clara Keiko Oliveira Watanabe, Serguei Vorobiov, Marco Giammarchi, Jon Paul Lundquist, A. Menshikov, R. Alves Batista, Bruce R. Dawson, F. Pedreira, Sofia Andringa, Julien Manshanden, Andres Travaini, E. Varela, J.D. Sanabria Gomez, Roberto Mussa, Frank G. Schröder, P.O. Mazur, Marina Scornavacche, Jonathan Biteau, F. Salamida, A. Yushkov, Paul Sommers, Maximilian Reininghaus, Raul Sarmento, Felix Schlüter, Fabian Gobbi, Ioana Codrina Maris, Violet M. Harvey, D. Harari, Martina Bohacova, G. P. Guedes, Toshihiro Fujii, Jakub Juryšek, John Farmer, D. Nitz, G. Cataldi, V. Scherini, J. Rautenberg, M. Risse, Jonathan Blazek, Q. Luce, Juan Pablo Gongora, Alena Bakalova, K. Choi, Esteban Roulet, D. Melo, M. Schimp, H. J. Mathes, A. Puyleart, Stanislav Michal, Corinne Berat, M. Giller, Orazio Zapparrata, B. C. Manning, Marcio Aparecido Muller, Maria-Teresa Dova, Markus Roth, R. Sato, Lourenco Lopes, P. Abreu, D. Ravignani, G. Golup, N. Kunka, T. Bister, Maria Rita Coluccia, G. C. Hill, Maximilian Stadelmaier, J. F. Valdés Galicia, I. De Mitri, N. Fazzini, Petr Hamal, Ana Martina Botti, Francesco Fenu, Steffen Hahn, Juan Carlos D'Olivo, T. Pierog, Antonio Condorelli, Alina Mihaela Badescu, Cristina Galea, Jonas Glombitza, F. C. T. Barbato, M. Prouza, Justin M. Albury, P. L. Ghia, L. R. Wiencke, S. Schröder, Niklas Langner, Italo Epicoco, G. Parente, Fabrizia Canfora, Jose J. Gonzalez, Dusan Mandat, Ralph Engel, J. Ridky, J. Rodriguez Rojo, Fridtjof Feldbusch, Enrique Zas, Lorenzo Caccianiga, L. Zehrer, Thomas Hebbeker, M. A. Leigui de Oliveira, Sergio Dasso, Tristan Sudholz, M. I. Micheletti, J. Chudoba, F. Riehn, Carola Dobrigkeit, M. Muzio, V. Novotny, A.L. Garcia Vegas, C. M. Schäfer, Marcel Köpke, M. Platino, François Montanet, A. Insolia, M. Kleifges, D. Zavrtanik, Fernando Contreras, Valerio Verzi, B. Tome, Martín Miguel Freire, Rossella Caruso, B. L. Lago, A. Lucero, Fernando Catalani, Bjarni Pont, E.E. Pereira Martins, J. de Oliveira, J. Pȩkala, Alejandro Almela, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, Brian Fick, Josina Schulte, V. Pirronello, C. J.W.P. Timmermans, Martin Vacula, Julian Kemp, Philipp Papenbreer, Rúben Conceição, M. E. Bertaina, Alan Watson, M. Perlin, Mihai Niculescu-Oglinzanu, L. Bonneau Arbeletche, G. Marsella, Petr Travnicek, Paula Gina Isar, Peter Hansen, W. M. Namasaka, M. Mastrodicasa, Carla Bleve, Rodrigo Guedes Lang, David Wittkowski, Lukáš Vaclavek, Belén Andrada, A. C. Rovero, Eleonora Guido, G. Mancarella, Jesús Peña-Rodríguez, B. Keilhauer, G. Salina, Olivier Deligny, Trent D. Grubb, F. Guarino, John Matthews, Peter Buchholz, Heino Falcke, Alexandru Balaceanu, Vladimir Lenok, P. Tobiska, L. Perrone, Alex Kääpä, Magdalena Cerdá, Juan Manuel Figueira, Roberta Colalillo, Carla Aramo, Matías J. Roncoroni, S. J. Sciutto, R.C. dos Anjos, A. G. Mariazzi, Adriana Vásquez-Ramírez, Vincenzo Rizi, Julien Souchard, D. Martello, J. Vicha, Hernán Asorey, A. Di Matteo, Juan Miguel Carceller, Silvia Mollerach, Flavia Gesualdi, Tomáš Fodran, Alina Nasr-Esfahani, M. Palatka, Xavier Bertou, Marco Aglietta, O. Martínez Bravo, B. Wundheiler, A. Zepeda, Miroslav Hrabovský, Pedro Assis, H. Martinez, A. Etchegoyen, Jeffrey A. Johnsen, L. Lu, H. Schieler, Ugo Giaccari, N. González, A. Segreto, J. F. Soriano, Günter Sigl, Antonella Castellina, A. Haungs, P. Stassi, Radomir Smida, A. Machado Payeras, Thomas Bretz, Gaia Silli, A. Filipčič, Kai Daumiller, F. Sanchez, Petr Janecek, Corbin Covault, F. Sarazin, Srijan Sehgal, Matías Rolf Hampel, Fernando Gollan, S. Petrera, Marc Weber, F. de Palma, P. Mantsch, Lino Miramonti, V. de Souza, D. de Oliveira Franco, G. Matthiae, Z. Szadkowski, Christian Sarmiento-Cano, P. Savina, W. Rodrigues de Carvalho, Antonio Bueno, G. Farrar, T. Huege, Jeffrey Brack, Olaf Scholten, Humberto Ibarguen Salazar, R. M. de Almeida, Gualberto Avila, Octavian Sima, Nataliia Borodai, Miguel Mostafa, A. Fuster, Samo Stanič, D. Lo Presti, D. Correia dos Santos, Isabel Goos, D. Heck, Rodrigo Pelayo, S. J. De Jong, L. Nellen, L. Anchordoqui, A. Taboada, Stijn Buitink, Katie Mulrey, M. del Río, Jarryd A. Day, A. Saftoiu, P.F. Gómez Vitale, C. Morello, A.C. Cobos Cerutti, T. Suomijärvi, D. Nosek, E. Santos, J. Pallotta, J. R. T. de Mello Neto, A. Weindl, Peter L. Biermann, David Schmidt, Paolo Privitera, Hernan Wahlberg, Darko Veberič, A. Parra, M. Schimassek, C. Hojvat, Jan Ebr, Jacco Vink, H.O. Klages, M. Trini, A. A. Nucita, J. Kleinfeller, Carlos Escobar, Kevin-Druis Merenda, A.D. Supanitsky, P.G. Brichetto Orchera, I. Allekotte, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, I.D. Vergara Quispe, J. Stasielak, K.-H. Becker, M. Pimenta, Denise Boncioli, P.R. Araújo Ferreira, Tobias Winchen, Florian Lukas Briechle, A. Aab, K. H. Kampert, J. C. Arteaga Velázquez, J. Perez Armand, Carla Taricco, C. Trimarelli, Matias Tueros, Claudio Galelli, B. García, R. López, Karen S. Caballero-Mora, Luis A. Nunez, Marcus Niechciol, Martin Erdmann, J. de Jesús, A. Streich, Gioacchino Alex Anastasi, M. Wirtz, Roger W Clay, S. Querchfeld, Olena Tkachenko, J. Šupík, Carlo Ventura, Ladislav Chytka, J. Hulsman, R. Squartini, Alfred Müller, G. Medina-Tanco, M. Zavrtanik, E. De Vito, Giovanni Consolati, C. J. Todero Peixoto, Petr Schovanek, Denis Stanca, H. Wilczyński, Ralf Ulrich, L. Nožka, Physics, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Muniz, J., Batista, R. A., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ferreira, P. R. A., Velazquez, J. C. A., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Luz, R. J. B., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Arbeletche, L. B., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Orchera, P. G. B., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., dos Santos, D. C., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesus, J., de Jong, S. J., de Mauro, G., de Mello Neto, J. R. T., de Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Palma, F., de Souza, V., de Vito, E., del Rio, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Vegas, A. L. G., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. G., Vitale, P. F. G., Gongora, J. P., Gonzalez, J. M., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Kunka, N., Lago, B. L., Lang, R. G., Langner, N., de Oliveira, M. A. L., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Lu, L., Luce, Q., Lucero, A., Lundquist, J. P., Payeras, A. M., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Bravo, O. M., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nunez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pekala, J., Pelayo, R., Pena-Rodriguez, J., Martins, E. E. P., Armand, J. P., Bertolli, C. P., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., de Carvalho, W. R., Rojo, J. R., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. S., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. T., Tome, B., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Galicia, J. F. V., Valore, L., Varela, E., Varma, V., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Quispe, I. D. V., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watanabe, C., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Research unit Astroparticle Physics, Alvarez-Mu??iz, J., Alves Batista, R., Ara??jo Ferreira, P. R., Arteaga Vel??zquez, J. C., Barreira Luz, R. J., Boh????ov??, M., Bonneau Arbeletche, L., Brichetto Orchera, P. G., Cobos Cerutti, A. C., Concei????o, R., Correia dos Santos, D., de Jes??s, J., De Mauro, G., De Mitri, I., De Vito, E., del R??o, M., Filip??i??, A., Garc??a, B., Garcia Vegas, A. L., G??mez Berisso, M., G??mez Vitale, P. F., Gonz??lez, J. M., Gonz??lez, N., G??ra, D., H??randel, J. R., Hrabovsk??, M., K????p??, A., K??pke, M., Leigui de Oliveira, M. A., L??pez, R., Machado Payeras, A., Mari??, I. C., Mart??nez Bravo, O., Mostaf??, M., M??ller, A. L., No??ka, L., N????ez, L. A., P??kala, J., Pe??a-Rodriguez, J., Pereira Martins, E. E., Perez Armand, J., P??rez Bertolli, C., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Sanabria Gomez, J. D., S??nchez, F., Sch??fer, C. M., Schl??ter, F., Schov??nek, P., Schr??der, F. G., Schr??der, S., m??da, R., Stani??, S., Su??rez-Dur??n, M., Suomij??rvi, T., up??k, J., Todero Peixoto, C. J., Tom??, B., Vald??s Galicia, J. F., Varma K. C., V., V??squez-Ram??rez, A., Veberi??, D., Vergara Quispe, I. D., Wilczy??ski, H., High Energy Astrophys. & Astropart. Phys (API, FNWI), Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Batista R.A., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Ferreira P.R.A., Velazquez J.C.A., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Luz R.J.B., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Arbeletche L.B., Borodai N., Botti A.M., Brack J., Bretz T., Orchera P.G.B., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cerutti A.C.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., dos Santos D.C., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., de Almeida R.M., de Jesus J., de Jong S.J., de Mauro G., de Mello Neto J.R.T., de Mitri I., de Oliveira J., de Oliveira Franco D., de Palma F., de Souza V., de Vito E., del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Vegas A.L.G., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Berisso M.G., Vitale P.F.G., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hamal P., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Janecek P., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kunka N., Lago B.L., Lang R.G., Langner N., de Oliveira M.A.L., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Lu L., Luce Q., Lucero A., Lundquist J.P., Payeras A.M., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Bravo O.M., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nasr-Esfahani A., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pekala J., Pelayo R., Pena-Rodriguez J., Martins E.E.P., Armand J.P., Bertolli C.P., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Rizi V., de Carvalho W.R., Rojo J.R., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Gomez J.D.S., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Segreto A., Sehgal S., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Taricco C., Timmermans C., Tkachenko O., Tobiska P., Peixoto C.J.T., Tome B., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Galicia J.F.V., Valore L., Varela E., Varma V., Vasquez-Ramirez A., Veberic D., Ventura C., Quispe I.D.V., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watanabe C., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., and Zepeda A.

Subjects
Photon, Physics::Instrumentation and Detectors, Astronomy, Electron, 01 natural sciences, High Energy Physics - Experiment, Auger, High Energy Physics - Experiment (hep-ex), mass [cosmic radiation], surface [detector], Observatory, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], photon: cosmic radiation, Instrumentation, Mathematical Physics, Physics, AGASA, Settore FIS/01 - Fisica Sperimentale, Detector, cosmic radiation [photon], Astrophysics::Instrumentation and Methods for Astrophysics, Monte Carlo [numerical calculations], electromagnetic [showers], observatory, cosmic radiation [electron], Analysis and statistical methods, numerical calculations: Monte Carlo, Analysis and statistical method, performance, positron: cosmic radiation, atmosphere [showers], Cherenkov detector, data analysis method, Calibration and fitting methods, Cherenkov detectors, Cluster finding, Large detector systems for particle and astroparticle physics, Pattern recognition, Cherenkov counter: water, air, neural network, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Cosmic ray, cosmic radiation [positron], cosmic radiation: mass, Calibration and fitting method, Nuclear physics, statistical analysis, 0103 physical sciences, showers: electromagnetic, ddc:530, ddc:610, High Energy Physics, 010306 general physics, Zenith, Pierre Auger Observatory, cosmic radiation [muon], Muon, showers: atmosphere, 010308 nuclear & particles physics, detector: surface, hep-ex, water [Cherenkov counter], electron: cosmic radiation, Recurrent neural network, muon: cosmic radiation, Large detector systems for particle and astroparticle physic, Experimental High Energy Physics, High Energy Physics::Experiment, RAIOS CÓSMICOS, experimental results
Abstract

The Pierre Auger Observatory, at present the largest cosmic-ray observatory ever built, is instrumented with a ground array of 1600 water-Cherenkov detectors, known as the Surface Detector (SD). The SD samples the secondary particle content (mostly photons, electrons, positrons and muons) of extensive air showers initiated by cosmic rays with energies ranging from $10^{17}~$eV up to more than $10^{20}~$eV. Measuring the independent contribution of the muon component to the total registered signal is crucial to enhance the capability of the Observatory to estimate the mass of the cosmic rays on an event-by-event basis. However, with the current design of the SD, it is difficult to straightforwardly separate the contributions of muons to the SD time traces from those of photons, electrons and positrons. In this paper, we present a method aimed at extracting the muon component of the time traces registered with each individual detector of the SD using Recurrent Neural Networks. We derive the performances of the method by training the neural network on simulations, in which the muon and the electromagnetic components of the traces are known. We conclude this work showing the performance of this method on experimental data of the Pierre Auger Observatory. We find that our predictions agree with the parameterizations obtained by the AGASA collaboration to describe the lateral distributions of the electromagnetic and muonic components of extensive air showers., Comment: Published version, 23 pages, 15 figures

Published
2022

15. Kidney Disease Management in the Hospital Setting: A Focus on Inappropriate Drug Prescriptions in Older Patients

Author

Vincenzo, Arcoraci, Maria Antonietta Barbieri, Michelangelo, Rottura, Alessandro, Nobili, Giuseppe, Natoli, Christiano, Argano, Giovanni, Squadrito, Francesco, Squadrito, Salvatore, Corrao, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Massimo, Raspanti, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Matteo, Cesari, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Alessandra, Marengoni, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio, Brucato, Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, DE GIORGI, Alfredo, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Francesco, Salerno, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Francesco, Violi, Ludovica, Perri, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Silvia, Ghidoni, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, Federica, Gandolfo., Arcoraci V., Barbieri M.A., Rottura M., Nobili A., Natoli G., Argano C., Squadrito G., Squadrito F., and Corrao S.

Subjects
medicine.medical_specialty, appropriateness of prescription, prescribing patterns, Renal function, Context (language use), RM1-950, Logistic regression, NO, chemistry.chemical_compound, older patient, Internal medicine, hospital setting, medicine, Pharmacology (medical), LS4_4, Medical prescription, prescribing pattern, appropriateness of prescriptions, chronic kidney disease, hospital setting, older patients, prescribing patterns, real-world data, Original Research, Pharmacology, Creatinine, real-world data, business.industry, Retrospective cohort study, medicine.disease, older patients, appropriateness of prescriptions, chronic kidney disease, chemistry, Observational study, Therapeutics. Pharmacology, business, Kidney disease
Abstract

Aging with multimorbidity and polytherapy are the most significant factors that could led to inappropriate prescribing of contraindicated medications in patients with chronic kidney disease (CKD). The aim of this study was to evaluate the prescriptions of contraindicated drugs in older adults in CKD and to identify their associated factors in a hospital context. An observational retrospective study was carried out considering all patients ≥65 years with at least one serum creatinine value recorded into the REPOSI register into 2010–2016 period. The estimated glomerular filtration rate (eGFR) was applied to identify CKD. A descriptive analysis was performed to compare demographic and clinical characteristics; logistic regression models were used to estimate factors of inappropriate and percentage changes of drug use during hospitalization. A total of 4,713 hospitalized patients were recorded, of which 49.8% had an eGFR 2; the 21.9% were in treatment with at least one inappropriate drug at the time of hospital admission with a decrease of 3.0% at discharge (p = 0.010). The probability of using at least one contraindicated drug was significantly higher in patients treated with more several drugs (OR 1.21, 95% CI 1.16–1.25, p p < 0.001; G5: 19.38, 11.51–32.64, p < 0.001). Low-dose acetylsalicylic acid was the contraindicated drug mainly used at the time of admission, reducing 1.2% at discharge. An overall increase in therapeutic appropriateness in hospitalized older patients with CKD was observed, despite a small percentage of therapeutic inappropriateness at discharge that underlines the need for a closer collaboration with the pharmacologist to improve the drug management.

Published
2021

16. The FRAM robotic telescope for atmospheric monitoring at the Pierre Auger Observatory

Author

Jose Chinellato, Ioana Caracas, Lorenzo Cazon, C. Pérez Bertolli, Ioana Codrina Maris, Marina Scornavacche, R. Ulrich, G. C. Hill, Jorge F. Soriano, Ralph Engel, M. Risse, H. J. Mathes, J. Ridky, Xavier Bertou, G. Marsella, David Wittkowski, G. Salina, Olivier Deligny, M. Unger, Tomáš Fodran, Alina Nasr-Esfahani, Stanislav Michal, Jonathan Blazek, Ugo Giaccari, J. Kleinfeller, K. Choi, Julien Manshanden, Andres Travaini, E. Varela, J.D. Sanabria Gomez, K.-H. Becker, M. Pimenta, P.R. Araújo Ferreira, Tobias Winchen, Denis Stanca, Florian Lukas Briechle, F. Canfora, G. Farrar, Antonio Condorelli, Carla Bleve, Rodrigo Guedes Lang, G. De Mauro, Silvia Mollerach, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, P. Abreu, D. Ravignani, Alena Bakalova, G. Matthiae, Jaime Alvarez-Muñiz, J. Rodriguez Rojo, Fridtjof Feldbusch, Enrique Zas, Marvin Gottowik, Carlos Escobar, Kevin-Druis Merenda, R.J. Barreira Luz, G. P. Guedes, G. Parente, L. Zehrer, A. Puyleart, Corinne Berat, M. Giller, Jörg R. Hörandel, Paul Sommers, P. Kubánek, Flavia Gesualdi, Fernando Contreras, Alexandru Gherghel-Lascu, Belén Andrada, P. Tobiska, Antonio Bueno, Violet M. Harvey, D. Harari, J. Chudoba, Valerio Pirronello, Gualberto Avila, B. García, Lukáš Vaclavek, Toshihiro Fujii, Dariusz Gora, Eric Mayotte, A. Zepeda, R. López, G. Mancarella, Pedro Assis, H. Martinez, A. Etchegoyen, Matías J. Roncoroni, Martina Bohacova, A. Aab, J. Biteau, I. Lhenry-Yvon, Karen S. Caballero-Mora, A.L. Garcia Vegas, B. Keilhauer, J. de Oliveira, A.D. Supanitsky, M. Gómez Berisso, Jakub Juryšek, Alejandro Almela, R. C. Shellard, S. J. Sciutto, A. Di Matteo, Alan Coleman, S. J. Saffi, B. Wundheiler, Marcel Köpke, Martin Erdmann, J. de Jesús, Juan Miguel Carceller, C. J. Todero Peixoto, Alina Mihaela Badescu, Cristina Galea, John Farmer, Serguei Vorobiov, M. Platino, Maria Rita Coluccia, Carla Taricco, M. Prouza, G. Cataldi, A. Streich, Gioacchino Alex Anastasi, D. Nitz, Juan Pablo Gongora, F. Pedreira, M. I. Micheletti, F. Salamida, M. Wirtz, Petr Hamal, B. L. Lago, P. Ruehl, Fred Sarazin, Thomas Bretz, A. Taboada, V. Scherini, A. Yushkov, Roger W Clay, Clara Keiko Oliveira Watanabe, Matias Tueros, Raul Sarmento, D. Melo, Mario Buscemi, Thomas Hebbeker, Maria-Teresa Dova, Sergio Dasso, Tristan Sudholz, Martin Vacula, Felix Schlüter, Magdalena Cerdá, E.E. Pereira Martins, Steffen Hahn, Juan Carlos D'Olivo, K. H. Kampert, T. Pierog, Fabian Gobbi, Christian Sarmiento-Cano, Hernán Asorey, Martín Miguel Freire, P.F. Gómez Vitale, Heino Falcke, Maximilian Reininghaus, L. R. Wiencke, Niklas Langner, J. C. Arteaga Velázquez, Petr Janecek, Brian Fick, M. Suárez-Durán, J. Vicha, Corbin Covault, Darko Veberič, Matías Rolf Hampel, Esteban Roulet, Rúben Conceição, R. Sato, Paula Gina Isar, J. Rautenberg, D. Nosek, F. Riehn, L. Nožka, Lourenco Lopes, M. Roth, S. Karpov, J. Perez Armand, E. Santos, Jesús Peña-Rodríguez, Q. Luce, Gaia Silli, Dusan Mandat, Justin M. Albury, A. Filipčič, T. Huege, F. Sanchez, Maximilian Stadelmaier, Frank G. Schröder, Lino Miramonti, Luis A. Nunez, A. Gorgi, A. Insolia, M. Kleifges, D. Zavrtanik, J. F. Valdés Galicia, Marcio Aparecido Muller, M. Zavrtanik, Antoine Letessier-Selvon, A. Fuster, L. Valore, I. De Mitri, Jeffrey Brack, S. Petrera, Marc Weber, W. M. Namasaka, M. Mastrodicasa, D. de Oliveira Franco, K. C. V. Varma, E. De Vito, Olaf Scholten, Marcus Niechciol, Humberto Ibarguen Salazar, C. M. Schäfer, A. C. Rovero, Giovanni Consolati, R.C. dos Anjos, Adriana Vásquez-Ramírez, E. M. Santos, A. Weindl, Bjarni Pont, Alexandru Balaceanu, M. A. Leigui de Oliveira, Roberto Mussa, Lorenzo Caccianiga, G. Golup, M. Palatka, R. Alves Batista, Bruce R. Dawson, C. Trimarelli, N. Kunka, H. Wilczyński, Claudio Galelli, L. Lu, Juan Manuel González, Carla Aramo, Vincenzo Rizi, P.O. Mazur, Julien Souchard, V. Novotny, C. J.W.P. Timmermans, D. Lo Presti, Rossella Caruso, A. Lucero, Fernando Catalani, D. Martello, S. J. De Jong, A. Tapia, Petr Schovanek, O. Martínez Bravo, Piera Luisa Ghia, T. Bister, Jon Paul Lundquist, A. Menshikov, H. Gemmeke, David Schmidt, S. Schröder, Italo Epicoco, M. Schimassek, François Montanet, Miguel Mostafa, Julian Kemp, S. Querchfeld, Sullivan Marafico, Olena Tkachenko, C. Hojvat, Jan Ebr, Valerio Verzi, Eleonora Guido, L. Nellen, Jarryd A. Day, A. Saftoiu, Marco Giammarchi, J. Šupík, Carlo Ventura, Octavian Sima, M. Mašek, B. Tome, C. Morello, Luis A. Anchordoqui, Jacco Vink, Alex Kääpä, Philipp Papenbreer, Samo Stanič, H.O. Klages, Petr Travnicek, L. Bonneau Arbeletche, Trent D. Grubb, Ladislav Chytka, A.C. Cobos Cerutti, R. Cunniffe, N. González, J. R. T. de Mello Neto, Peter L. Biermann, Juan Manuel Figueira, Isabel Goos, Roberta Colalillo, A. G. Mariazzi, J. Stasielak, Kai Daumiller, H. Schieler, Paolo Privitera, A. A. Nucita, Antonella Castellina, D. Heck, M. del Río, I. Ebrová, Denise Boncioli, P. Savina, W. Rodrigues de Carvalho, M. Jelínek, Jeffrey A. Johnsen, Nataliia Borodai, A. Segreto, Vladimir Lenok, L. Perrone, J. Hulsman, Günter Sigl, R. Squartini, Alfred Müller, P. Stassi, Radomir Smida, A. Machado Payeras, J. Eliášek, G. Medina-Tanco, Srijan Sehgal, Miroslav Pech, M. Pothast, Fernando Gollan, F. de Palma, Pavel Horvath, V. de Souza, Sofia Andringa, M. Schimp, B. C. Manning, Ana Martina Botti, Francesco Fenu, Miroslav Hrabovský, A. Haungs, Josina Schulte, Peter Hansen, P. Mantsch, Z. Szadkowski, J. Pkala, F. Guarino, John Matthews, Peter Buchholz, Marco Aglietta, R. M. de Almeida, D. Correia dos Santos, Rodrigo Pelayo, Stijn Buitink, Katie Mulrey, Orazio Zapparrata, Carola Dobrigkeit, M. Muzio, M. E. Bertaina, Alan Watson, M. Perlin, Mihai Niculescu-Oglinzanu, T. Suomijärvi, J. Pallotta, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, I.D. Vergara Quispe, Hernan Wahlberg, A. Parra, M. Trini, P.G. Brichetto Orchera, I. Allekotte, High Energy Astrophys. & Astropart. Phys (API, FNWI), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Mu??iz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ara??jo Ferreira, P. R., Arteaga Vel??zquez, J. C., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Boh????ov??, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Brichetto Orchera, P. G., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Concei????o, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Correia dos Santos, D., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jes??s, J., de Jong, S. J., De Mauro, G., de Mello Neto, J. R. T., De Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Palma, F., de Souza, V., De Vito, E., del R??o, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filip??i??, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garc??a, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., G??mez Berisso, M., G??mez Vitale, P. F., Gongora, J. P., Gonz??lez, J. M., Gonz??lez, N., Goos, I., G??ra, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., H??randel, J. R., Horvath, P., Hrabovsk??, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., K????p??, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., K??pke, M., Kunka, N., Lago, B. L., Lang, R. G., Langner, N., Leigui de Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., L??pez, R., Lu, L., Luce, Q., Lucero, A., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Mari??, I. C., Marsella, G., Martello, D., Martinez, H., Mart??nez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostaf??, M., M??ller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., No??ka, L., Nucita, A., N????ez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., P??kala, J., Pelayo, R., Pe??a-Rodriguez, J., Pereira Martins, E. E., Perez Armand, J., P??rez Bertolli, C., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., S??nchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Sch??fer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schl??ter, F., Schmidt, D., Scholten, O., Schov??nek, P., Schr??der, F. G., Schr??der, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shellard, R. C., Sigl, G., Silli, G., Sima, O., m??da, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stani??, S., Stasielak, J., Stassi, P., Streich, A., Su??rez-Dur??n, M., Sudholz, T., Suomij??rvi, T., Supanitsky, A. D., up??k, J., Szadkowski, Z., Taboada, A., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tom??, B., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Vald??s Galicia, J. F., Valore, L., Varela, E., Varma K. C., V., V??squez-Ram??rez, A., Veberi??, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watanabe, C., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczy??ski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Cunniffe, R., Eli????ek, J., Ebrov??, I., Jel??nek, M., Karpov, S., Kub??nek, P., Ma??ek, M., Pierre Auger Collaboration, T., Alvarez-Muniz, J., Araujo Ferreira, P. R., Arteaga Velazquez, J. C., Bohacova, M., Conceicao, R., Correia Dos Santos, D., De Almeida, R. M., De Jesus, J., De Jong, S. J., De Mello Neto, J. R. T., De Oliveira, J., De Oliveira Franco, D., De Palma, F., De Souza, V., Del Rio, M., Dos Anjos, R. C., Filipcic, A., Garcia, B., Gomez Berisso, M., Gomez Vitale, P. F., Gonzalez, J. M., Gonzalez, N., Gora, D., Horandel, J. R., Hrabovsky, M., Kaapa, A., Kopke, M., Leigui De Oliveira, M. A., Lopez, R., Maris, I. C., Martinez Bravo, O., Mostafa, M., Muller, A. L., Nozka, L., Nunez, L. A., Pkala, J., Pena-Rodriguez, J., Perez Bertolli, C., Rodrigues De Carvalho, W., Sanchez, F., Schafer, C. M., Schluter, F., Schovanek, P., Schroder, F. G., Schroder, S., Smida, R., Stanic, S., Suarez-Duran, M., Suomijarvi, T., Supik, J., Tome, B., Valdes Galicia, J. F., Varma, K. C. V., Vasquez-Ramirez, A., Veberic, D., Wilczynski, H., Eliasek, J., Ebrova, I., Jelinek, M., Kubanek, P., Masek, M., Research unit Astroparticle Physics, Pierre Auger Collaboration T., Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Alves Batista R., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Araujo Ferreira P.R., Arteaga Velazquez J.C., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Bonneau Arbeletche L., Borodai N., Botti A.M., Brack J., Bretz T., Brichetto Orchera P.G., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Correia Dos Santos D., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., De Almeida R.M., De Jesus J., De Jong S.J., De Mauro G., De Mello Neto J.R.T., De Mitri I., De Oliveira J., De Oliveira Franco D., De Palma F., De Souza V., De Vito E., Del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., Dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Garcia Vegas A.L., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hamal P., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Janecek P., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kunka N., Lago B.L., Lang R.G., Langner N., Leigui De Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Lu L., Luce Q., Lucero A., Lundquist J.P., Machado Payeras A., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nasr-Esfahani A., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pkala J., Pelayo R., Pena-Rodriguez J., Pereira Martins E.E., Perez Armand J., Perez Bertolli C., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Rizi V., Rodrigues De Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Segreto A., Sehgal S., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Taricco C., Timmermans C., Tkachenko O., Tobiska P., Todero Peixoto C.J., Tome B., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Valdes Galicia J.F., Valore L., Varela E., Varma K.C.V., Vasquez-Ramirez A., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watanabe C., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., Cunniffe R., Eliasek J., Ebrova I., Jelinek M., Karpov S., Kubanek P., Masek M., and Physics

Subjects
Astronomy, Large detector systems for particle and astroparticle physics, Optics, Photon detectors for UV, visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc), Real-time monitoring, 01 natural sciences, Auger, Successful operation, Observatory, optical, APDs, hardware, Astrophysics::Solar and Stellar Astrophysics, 010303 astronomy & astrophysics, Instrumentation, Photon detectors for UV, Mathematical Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, EBCCDs, Settore FIS/01 - Fisica Sperimentale, Astrophysics::Instrumentation and Methods for Astrophysics, Si-PMTs, observatory, Robotic telescope, G-APDs, Astrophysics::Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Sciences exactes et naturelles, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, programming, detector: fluorescence, Photometry (optics), 0103 physical sciences, ddc:610, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], High Energy Physics, visible and IR photons (solid-state) (PIN diodes, CMOS imagers, Instrumentation and Methods for Astrophysics (astro-ph.IM), Astrophysics::Galaxy Astrophysics, Remote sensing, etc), fluorescence [detector], Pierre Auger Observatory, 010308 nuclear & particles physics, Active monitoring, CCDs, laser, monitoring, EMCCDs, Large detector systems for particle and astroparticle physic, atmosphere, Experimental High Energy Physics, Optic, Environmental science, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], RAIOS CÓSMICOS, astro-ph.IM
Abstract

FRAM (F/Photometric Robotic Atmospheric Monitor) is a robotic telescope operated at the Pierre Auger Observatory in Argentina for the purposes of atmospheric monitoring using stellar photometry. As a passive system which does not produce any light that could interfere with the observations of the fluorescence telescopes of the observatory, it complements the active monitoring systems that use lasers. We discuss the applications of stellar photometry for atmospheric monitoring at optical observatories in general and the particular modes of operation employed by the Auger FRAM. We describe in detail the technical aspects of FRAM, the hardware and software requirements for a successful operation of a robotic telescope for such a purpose and their implementation within the FRAM system., Published version, 27 pages, 8 figures

Published
2021

17. Calibration strategy of the JUNO experiment

Author

Andrea Barresi, Muhammad Usman Rajput, Chengzhuo Yuan, Demin Li, Cédric Huss, Jie Zhao, Xianghui Yu, W. H. Huang, Feng Gao, Sen Qian, Patrick Kinz, Miao He, Axel Müller, Davit Mayilyan, Utane Sawangwit, Jacques Wurtz, Wenju Huo, Hang Hu, Guanghua Gong, G. Andronico, Giuseppe Verde, Si Ma, Livia Ludhova, Xiaoyu Yang, Lucia Votano, Waqas Muhammad, Oleg Smirnov, Jie Yang, Zhe Ning, Y. X. Zhang, Zhuang Shao, Jun Wang, Martin Dvorak, Hao Liang, Nikolay Morozov, Ara Ioannisian, Qingmin Zhang, Ezio Previtali, Barbara Ricci, Ints Mednieks, Wuming Luo, Rossella Caruso, Diru Wu, Alexander Studenikin, Sadia Marium, Jingbo Zhang, M. Settimo, A. Popov, Enrico Bernieri, Xiaowei Liu, Yumei Zhang, Anut Sangka, Feipeng Ning, F. Z. Qi, Simon Blyth, Anatael Cabrera, Antonio Insolia, Donglian Xu, Amir N. Khan, Minghao Gu, Daniel Liebau, Shouyang Hu, Thilo Birkenfeld, Mengyun Guan, Gérard Claverie, Xin Mao, Xingtao Huang, Guoqing Zhang, Markus Robens, Jari Joutsenvaara, Zhibing Li, Can Fang, Nuanwan Sanguansak, Andrey Formozov, Ugur Yegin, Yuekun Heng, Xiaohui Qian, Riccardo Bruno, Zafar Yasin, Selma Conforti Di Lorenzo, Weidong Li, Xiaonan Li, Cédric Schwab, Yuguang Xie, Narumon Suwonjandee, Michael Wurm, Teerapat Payupol, Andrea Serafini, Chunhao Huang, Fangliang Wu, Haoqi Lu, Di Jiang, Salvatore Costa, Yue Meng, Y. Sun, S. Dusini, Mathieu Roche, Stefano Maria Mari, S. Parmeggiano, N. Raper, M. A. Szelezniak, W. J. Wu, Jingbin Lu, Heike Enzmann, Nan Li, Zhonghua Qin, Min Liu, Q. J. Li, Tobias Heinz, Frédéric Druillole, Qun Wu, Anbo Yang, Hongjuan Liu, Sukit Limpijumnong, Peihuai Yi, Cecilia Landini, Jonathan Miller, Yu Xu, Agnese Martini, Vito Antonelli, A. Bolshakova, Alexandre Göttel, X. L. Ji, Yuanqing Wang, Haonan Gan, Lei Yang, Sebastiano Aiello, Leonidas Kalousis, Andre Zambanini, R. T. Lei, Stefan van Waasen, Dmitry Selivanov, Khanchai Khosonthongkee, Yanke Cai, F. Yermia, Yuman Wang, Rong Zhao, Jian Wang, E. Meroni, Filippo Marini, Narine Kazarian, Y. F. Wang, Shanfeng Li, Q. An, Alessandra Re, Chung-Hsiang Wang, Agnese Giaz, Tingxuan Zeng, Guihong Huang, Andrej Babic, Fabio Mantovani, Fang Liu, Richard Ford, Zhe Wang, Christian Grewing, Antonio Bergnoli, Warintorn Sreethawong, Georgy Donchenko, S. Krokhaleva, Mengzhao Li, Rupert Leitner, Monica Sisti, Domizia Orestano, Mario Buscemi, Paolo Montini, Marco Grassi, Zeyuan Yu, Tobias Lachenmaier, Jianrun Hu, Victor Lebrin, Angel Abusleme, Boxiang Yu, Tao Li, Maciej Slupecki, Boonrucksar Soonthornthum, Catia Clementi, Marco Giammarchi, Francesco Manzali, B. Z. Hu, Virginia Strati, Alexey Krasnoperov, Zhang Chen, Hua Zheng, P. Saggese, Minshan Zheng, Xiaolu Ji, Gisele Martin-Chassard, Matthias Raphael Stock, Pablo Walker, Jose Busto, Agustin Campeny, Burin Asavapibhop, Yinhong Zhang, S. B. Liu, Vitaly Shutov, Barbara Clerbaux, Peng Zhang, Zhengyun You, Yayun Ding, Shubin Liu, Ayut Limphirat, S. Dmitrievsky, Siyu Jian, S. Sanfilippo, Cristina Tuve, Shoukang Qiu, Shifeng Sun, Jie Ren, Sébastien Leblanc, Po-An Chen, Xubo Ma, Safeer Hussain, Guangpeng An, Nicomede Pelliccia, Yuhang Guo, Shan Zeng, Konstantin A. Kouzakov, Shaojing Hou, Jing Xu, X. H. Guo, Feiyang Zhang, Dongqin Zheng, Ilya Butorov, Maria Gul, Kunyu Wang, Claudio Lombardo, Zhi Deng, Zhiyan Cai, Yu Gu, Yufei Xi, K. Loo, R. Brugnera, Shu Luo, Jiaheng Zou, Ran Han, Giancarlo Troni, M. H. Ye, Xiaoxu Lu, Fengjiao Luo, H. D. Liu, Haitao Li, Fei Li, Julanan Songwadhana, Xiaomei Zhang, Fengpeng An, X. D. Ruan, Chunxu Yu, Vadim Vedin, Mauro Mezzetto, Jiaqi Li, Caren Hagner, Shu Zhang, Wander Baldini, Yangheng Zheng, Antonio Budano, Michele Montuschi, Zheng Wang, Qin Liu, Pierre-Alexandre Petitjean, Xuefeng Ding, H. R. Pan, Lukas Fajt, Jingyan Shi, David Meyhöfer, Fanrong Xu, Marco Bellato, Zhenyu Zhang, S. J. Zhao, Clément Bordereau, Yan Zhang, Bayarto Lubsandorzhiev, Guang Luo, Benda Xu, Xiangyue Wang, Christophe De La Taille, Miao Yu, Christian Roth, Nina Parkalian, Andrea Fabbri, Fausto Ortica, João Pedro Athayde Marcondes de André, Y. Wang, Liangjian Wen, S. X. Du, Jian Tang, Frederic Lefevre, Tao Hu, Vasily Gromov, Guofu Cao, Liang Zhan, E. Doroshkevich, Steven Chan-Fai Wong, Amélie Fournier, Apimook Watcharangkool, Jinchang Liu, Qian Liu, Yongbo Huang, Bayu Dirgantara, Chiara Sirignano, Qiumei Ma, Yi Wang, A. Sadovsky, Xichao Ruan, Caishen Wang, G. Settanta, Flavio Dal Corso, Beatrice Jelmini, Guillaume Vanroyen, Baojun Yan, Ruhui Li, Mikhail Smirnov, Huan Yang, Z. Wu, Xiao Cai, Yun Chang, Meng Wang, Yufeng Li, Tianchi Zhao, K. L. Jen, Li-Cheng Feng, Guey-Lin Lin, Shuxiang Lu, Massimiliano Nastasi, Thomas Adam, Rizwan Ahmed, David Blum, Marco Fargetta, Didier Auguste, Weiguo Li, Jian Fang, Patrick Hellmuth, Muhammad Akram, Hui Liu, Tomas Tmej, G. X. Sun, Fengyi Zhao, Christian Wysotzki, Wladyslaw Henryk Trzaska, Achim Stahl, Sylvie Blin, Yin Xu, Alexander Tietzsch, Fedor Šimkovic, Haiping Peng, Ziping Ye, Baobiao Yue, A. Sotnikov, Aldo Romani, Anna Chuvashova, Noman Zafar, Tatiana Antoshkina, Wanlei Guo, C. Jollet, Christoph Genster, Sultim Lubsandorzhiev, Y. K. Sun, Xiangwei Yin, Xiaoping Jing, H. Steiger, Muhammad Sohaib Hassan, Cristina Martellini, Wei Wang, B. Viaud, Igor Nemchenok, Zhijian Zhang, Fatma Sawy, Xiaofei Gu, Alexander Olshevskiy, Liang Zong, Pavithra Muralidharan, Xiaomei Li, Alexandr Selyunin, Yu Chen, Jochen Steinmann, Qiang Tang, Daojin Hong, Daniele Corti, Yatian Pei, S. Zhang, Denis Korablev, Yi Chen, Dominique Breton, Franco Giuliani, F. Li, Augusto Brigatti, Artem Chukanov, Nikolaos Vassilopoulos, Jiaxuan Ye, Yi-Wen Chen, K. Treskov, Michael Karagounis, Haiqiong Zhang, Jiang Zhu, Nunzio Giudice, Zongyi Wang, H. L. Zhuang, Marco Aurelio Diaz, Nikolay Kutovskiy, Shakeel Ahmad, Narongkiat Rodphai, Yifan Yang, Huihui Jia, Juan Pedro Ochoa-Ricoux, Jin Li, Hongtao Liu, Andrey Sidorenkov, Qichun Feng, Jiawen Zhang, T. Enqvist, Ruyi Jin, J. J. Ling, Arseniy Rybnikov, Lino Miramonti, Yi Li, Luis Felipe Piñeres Rico, Ziyuan Li, Ziyi Yuan, A. Lokhov, Jie Cheng, Rafael Herrera, Jiaqi Hui, Wathan Pratumwan, En Wang, Konstantin Schweizer, A. Kruth, Tobias Sterr, Shengxin Lin, Anna Fatkina, Fabrizio Petrucci, Mathieu Bongrand, Olivia Dalager, Alessandro Paoloni, Philipp Kampmann, Roberto Isocrate, Jianmeng Dong, Weirong Zhong, Yiyu Zhang, Saroj Rujirawat, Giuseppe Salamanna, Maxim Vialkov, Abdel Rebii, Mengjiao Xiao, Jing Zhou, P. Chimenti, Jingjing Liang, Yuanyuan Zhang, Pingping Chen, Igor Tkachev, A. Cammi, Oliver Pilarczyk, Vit Vorobel, Zhimin Wang, Honghao Zhang, Zhenxiong Yuan, Xiang Zhou, Damien Dornic, Jie Zhang, Zhangquan Xie, Yaping Cheng, Ying Yuan, Maxim Gonchar, Wei Wei, Zhuojun Hu, Ivano Lippi, Xilei Sun, Shaomin Chen, Jun Cao, Li Zhou, Ruiguang Wang, Nikolay Anfimov, Andrea Triossi, Runxuan Liu, Xinglong Li, Waseem Khan, Pasi Kuusiniemi, Xi Wang, Salvatore Monforte, Meihang Xu, Eric Baussan, Haifeng Yao, Xuantong Zhang, Yang Han, Pascal Poussot, Dongmei Xia, Jacky Schuler, Hao Qiao, Hu Liu, Henning Rebber, Dmitry V. Naumov, Luca Stanco, Paul Hackspacher, Y. K. Hor, Lei Fan, Ziyan Deng, Lei Huo, Ondrej Sramek, K. J. Li, Jianglai Liu, Lu Wang, Paolo Lombardi, Marcos Dracos, B. Roskovec, Taras Rezinko, Quan Tang, Jiawei Deng, Jason Leung, Xiao Tang, Junji Jia, Huiling Li, Nunzio Guardone, Chuanya Cao, Diana Navas-Nicolas, A. Meregaglia, Zhi-zhong Xing, V. Fekete, Jilei Xu, W. Wang, Siguang Wang, Yupeng Yan, Hao Cai, Christopher Wiebusch, Y. B. Hsiung, Z. V. Krumshteyn, Sirichok Jungthawan, Thiago Sogo-Bezerra, Yury Malyshkin, S. Li, Dmitry Fedoseev, Tao Lin, Chuan Lu, J. F. Chang, Davide Chiesa, Changgen Yang, A. Garfagnini, F. Perrot, Wilfried Depnering, Xiaoyan Ma, Yadong Wei, M. Wang, O. Gorchakov, Yajun Mao, Anguo Peng, C. Cerna, Wei He, Lothar Oberauer, Konstantin Stankevich, Yuri Gornushkin, Donghua Fan, Cong Guo, Dušan Štefánik, Ming Qi, Lianghong Wei, Jihane Maalmi, E. Naumova, Jaruchit Siripak, Tadeas Dohnal, Julia Sawatzki, Hongbang Liu, X. R. Chen, Bjoern Wonsak, Vladimir Lyashuk, Johannes van den Boom, Qinhua Huang, Jingyuan Guo, Yuda Zeng, Shulin Liu, Tao Zhang, Guo-Li Wang, Hui Gong, Michaela Schever, Jun Hu, K. J. Zhu, P. W. Luo, Shun Zhou, Bin Ren, Nan Zhou, Yan Liu, Li Kang, Junguang Lu, Gioacchino Ranucci, Chiye Yu, Cheng Xu, Hongzhao Yu, Hanxiong Huang, Xiongbo Yan, Sai-Juan Chen, C. Volpe, Hiroshi Nunokawa, Yanchu Wang, Vladislav Sharov, Xiaoshan Jiang, Abusleme, A, Adam, T, Ahmad, S, Ahmed, R, Aiello, S, Akram, M, An, F, An, G, An, Q, Andronico, G, Anfimov, N, Antonelli, V, Antoshkina, T, Asavapibhop, B, de Andre, J, Auguste, D, Babic, A, Baldini, W, Barresi, A, Baussan, E, Bellato, M, Bergnoli, A, Bernieri, E, Birkenfeld, T, Blin, S, Blum, D, Blyth, S, Bolshakova, A, Bongrand, M, Bordereau, C, Breton, D, Brigatti, A, Brugnera, R, Bruno, R, Budano, A, Buscemi, M, Busto, J, Butorov, I, Cabrera, A, Cai, H, Cai, X, Cai, Y, Cai, Z, Cammi, A, Campeny, A, Cao, C, Cao, G, Cao, J, Caruso, R, Cerna, C, Chang, J, Chang, Y, Chen, P, Chen, S, Chen, X, Chen, Y, Chen, Z, Cheng, J, Cheng, Y, Chiesa, D, Chimenti, P, Chukanov, A, Chuvashova, A, Claverie, G, Clementi, C, Clerbaux, B, Lorenzo, S, Corti, D, Costa, S, Corso, F, Dalager, O, Taille, C, Deng, J, Deng, Z, Depnering, W, Diaz, M, Ding, X, Ding, Y, Dirgantara, B, Dmitrievsky, S, Dohnal, T, Donchenko, G, Dong, J, Dornic, D, Doroshkevich, E, Dracos, M, Druillole, F, Du, S, Dusini, S, Dvorak, M, Enqvist, T, Enzmann, H, Fabbri, A, Fajt, L, Fan, D, Fan, L, Fang, C, Fang, J, Fargetta, M, Fatkina, A, Fedoseev, D, Fekete, V, Feng, L, Feng, Q, Ford, R, Formozov, A, Fournier, A, Gan, H, Gao, F, Garfagnini, A, Gottel, A, Genster, C, Giammarchi, M, Giaz, A, Giudice, N, Giuliani, F, Gonchar, M, Gong, G, Gong, H, Gorchakov, O, Gornushkin, Y, Grassi, M, Grewing, C, Gromov, V, Gu, M, Gu, X, Gu, Y, Guan, M, Guardone, N, Gul, M, Guo, C, Guo, J, Guo, W, Guo, X, Guo, Y, Hackspacher, P, Hagner, C, Han, R, Han, Y, Hassan, M, He, M, He, W, Heinz, T, Hellmuth, P, Heng, Y, Herrera, R, Hong, D, Hor, Y, Hou, S, Hsiung, Y, Hu, B, Hu, H, Hu, J, Hu, S, Hu, T, Hu, Z, Huang, C, Huang, G, Huang, H, Huang, Q, Huang, W, Huang, X, Huang, Y, Hui, J, Huo, L, Huo, W, Huss, C, Hussain, S, Insolia, A, Ioannisian, A, Isocrate, R, Jelmini, B, Jen, K, Ji, X, Jia, H, Jia, J, Jian, S, Jiang, D, Jiang, X, Jin, R, Jing, X, Jollet, C, Joutsenvaara, J, Jungthawan, S, Kalousis, L, Kampmann, P, Kang, L, Karagounis, M, Kazarian, N, Khan, A, Khan, W, Khosonthongkee, K, Kinz, P, Korablev, D, Kouzakov, K, Krasnoperov, A, Krokhaleva, S, Krumshteyn, Z, Kruth, A, Kutovskiy, N, Kuusiniemi, P, Lachenmaier, T, Landini, C, Leblanc, S, Lebrin, V, Lefevre, F, Lei, R, Leitner, R, Leung, J, Li, D, Li, F, Li, H, Li, J, Li, K, Li, M, Li, N, Li, Q, Li, R, Li, S, Li, T, Li, W, Li, X, Li, Y, Li, Z, Liang, H, Liang, J, Liebau, D, Limphirat, A, Limpijumnong, S, Lin, G, Lin, S, Lin, T, Ling, J, Lippi, I, Liu, F, Liu, H, Liu, J, Liu, M, Liu, Q, Liu, R, Liu, S, Liu, X, Liu, Y, Lokhov, A, Lombardi, P, Lombardo, C, Loo, K, Lu, C, Lu, H, Lu, J, Lu, S, Lu, X, Lubsandorzhiev, B, Lubsandorzhiev, S, Ludhova, L, Luo, F, Luo, G, Luo, P, Luo, S, Luo, W, Lyashuk, V, Ma, Q, Ma, S, Ma, X, Maalmi, J, Malyshkin, Y, Mantovani, F, Manzali, F, Mao, X, Mao, Y, Mari, S, Marini, F, Marium, S, Martellini, C, Martin-Chassard, G, Martini, A, Mayilyan, D, Muller, A, Mednieks, I, Meng, Y, Meregaglia, A, Meroni, E, Meyhofer, D, Mezzetto, M, Miller, J, Miramonti, L, Monforte, S, Montini, P, Montuschi, M, Morozov, N, Muhammad, W, Muralidharan, P, Nastasi, M, Naumov, D, Naumova, E, Navas-Nicolas, D, Nemchenok, I, Ning, F, Ning, Z, Nunokawa, H, Oberauer, L, Ochoa-Ricoux, J, Olshevskiy, A, Orestano, D, Ortica, F, Pan, H, Paoloni, A, Parkalian, N, Parmeggiano, S, Payupol, T, Pei, Y, Pelliccia, N, Peng, A, Peng, H, Perrot, F, Petitjean, P, Petrucci, F, Rico, L, Pilarczyk, O, Popov, A, Poussot, P, Pratumwan, W, Previtali, E, Qi, F, Qi, M, Qian, S, Qian, X, Qiao, H, Qin, Z, Qiu, S, Rajput, M, Ranucci, G, Raper, N, Re, A, Rebber, H, Rebii, A, Ren, B, Ren, J, Rezinko, T, Ricci, B, Robens, M, Roche, M, Rodphai, N, Romani, A, Roskovec, B, Roth, C, Ruan, X, Rujirawat, S, Rybnikov, A, Sadovsky, A, Saggese, P, Salamanna, G, Sanfilippo, S, Sangka, A, Sanguansak, N, Sawangwit, U, Sawatzki, J, Sawy, F, Schever, M, Schuler, J, Schwab, C, Schweizer, K, Selivanov, D, Selyunin, A, Serafini, A, Settanta, G, Settimo, M, Shao, Z, Sharov, V, Shi, J, Shutov, V, Sidorenkov, A, Simkovic, F, Sirignano, C, Siripak, J, Sisti, M, Slupecki, M, Smirnov, M, Smirnov, O, Sogo-Bezerra, T, Songwadhana, J, Soonthornthum, B, Sotnikov, A, Sramek, O, Sreethawong, W, Stahl, A, Stanco, L, Stankevich, K, Stefanik, D, Steiger, H, Steinmann, J, Sterr, T, Stock, M, Strati, V, Studenikin, A, Sun, G, Sun, S, Sun, X, Sun, Y, Suwonjandee, N, Szelezniak, M, Tang, J, Tang, Q, Tang, X, Tietzsch, A, Tkachev, I, Tmej, T, Treskov, K, Triossi, A, Troni, G, Trzaska, W, Tuve, C, van Waasen, S, van den Boom, J, Vanroyen, G, Vassilopoulos, N, Vedin, V, Verde, G, Vialkov, M, Viaud, B, Volpe, C, Vorobel, V, Votano, L, Walker, P, Wang, C, Wang, E, Wang, G, Wang, J, Wang, K, Wang, L, Wang, M, Wang, R, Wang, S, Wang, W, Wang, X, Wang, Y, Wang, Z, Watcharangkool, A, Wei, L, Wei, W, Wei, Y, Wen, L, Wiebusch, C, Wong, S, Wonsak, B, Wu, D, Wu, F, Wu, Q, Wu, W, Wu, Z, Wurm, M, Wurtz, J, Wysotzki, C, Xi, Y, Xia, D, Xiao, M, Xie, Y, Xie, Z, Xing, Z, Xu, B, Xu, C, Xu, D, Xu, F, Xu, J, Xu, M, Xu, Y, Yan, B, Yan, X, Yan, Y, Yang, A, Yang, C, Yang, H, Yang, J, Yang, L, Yang, X, Yang, Y, Yao, H, Yasin, Z, Ye, J, Ye, M, Ye, Z, Yegin, U, Yermia, F, Yi, P, Yin, X, You, Z, Yu, B, Yu, C, Yu, H, Yu, M, Yu, X, Yu, Z, Yuan, C, Yuan, Y, Yuan, Z, Yue, B, Zafar, N, Zambanini, A, Zeng, S, Zeng, T, Zeng, Y, Zhan, L, Zhang, F, Zhang, G, Zhang, H, Zhang, J, Zhang, P, Zhang, Q, Zhang, S, Zhang, T, Zhang, X, Zhang, Y, Zhang, Z, Zhao, F, Zhao, J, Zhao, R, Zhao, S, Zhao, T, Zheng, D, Zheng, H, Zheng, M, Zheng, Y, Zhong, W, Zhou, J, Zhou, L, Zhou, N, Zhou, S, Zhou, X, Zhu, J, Zhu, K, Zhuang, H, Zong, L, Zou, J, Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), JUNO, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Abusleme A., Adam T., Ahmad S., Ahmed R., Aiello S., Akram M., An F., An G., An Q., Andronico G., Anfimov N., Antonelli V., Antoshkina T., Asavapibhop B., de Andre J.P.A.M., Auguste D., Babic A., Baldini W., Barresi A., Baussan E., Bellato M., Bergnoli A., Bernieri E., Birkenfeld T., Blin S., Blum D., Blyth S., Bolshakova A., Bongrand M., Bordereau C., Breton D., Brigatti A., Brugnera R., Bruno R., Budano A., Buscemi M., Busto J., Butorov I., Cabrera A., Cai H., Cai X., Cai Y., Cai Z., Cammi A., Campeny A., Cao C., Cao G., Cao J., Caruso R., Cerna C., Chang J., Chang Y., Chen P., Chen P.-A., Chen S., Chen X., Chen Y.-W., Chen Y., Chen Z., Cheng J., Cheng Y., Chiesa D., Chimenti P., Chukanov A., Chuvashova A., Claverie G., Clementi C., Clerbaux B., Lorenzo S.C.D., Corti D., Costa S., Corso F.D., Dalager O., Taille C.D.L., Deng J., Deng Z., Depnering W., Diaz M., Ding X., Ding Y., Dirgantara B., Dmitrievsky S., Dohnal T., Donchenko G., Dong J., Dornic D., Doroshkevich E., Dracos M., Druillole F., Du S., Dusini S., Dvorak M., Enqvist T., Enzmann H., Fabbri A., Fajt L., Fan D., Fan L., Fang C., Fang J., Fargetta M., Fatkina A., Fedoseev D., Fekete V., Feng L.-C., Feng Q., Ford R., Formozov A., Fournier A., Gan H., Gao F., Garfagnini A., Gottel A., Genster C., Giammarchi M., Giaz A., Giudice N., Giuliani F., Gonchar M., Gong G., Gong H., Gorchakov O., Gornushkin Y., Grassi M., Grewing C., Gromov V., Gu M., Gu X., Gu Y., Guan M., Guardone N., Gul M., Guo C., Guo J., Guo W., Guo X., Guo Y., Hackspacher P., Hagner C., Han R., Han Y., Hassan M., He M., He W., Heinz T., Hellmuth P., Heng Y., Herrera R., Hong D., Hor Y., Hou S., Hsiung Y., Hu B.-Z., Hu H., Hu J., Hu S., Hu T., Hu Z., Huang C., Huang G., Huang H., Huang Q., Huang W., Huang X., Huang Y., Hui J., Huo L., Huo W., Huss C., Hussain S., Insolia A., Ioannisian A., Isocrate R., Jelmini B., Jen K.-L., Ji X., Jia H., Jia J., Jian S., Jiang D., Jiang X., Jin R., Jing X., Jollet C., Joutsenvaara J., Jungthawan S., Kalousis L., Kampmann P., Kang L., Karagounis M., Kazarian N., Khan A., Khan W., Khosonthongkee K., Kinz P., Korablev D., Kouzakov K., Krasnoperov A., Krokhaleva S., Krumshteyn Z., Kruth A., Kutovskiy N., Kuusiniemi P., Lachenmaier T., Landini C., Leblanc S., Lebrin V., Lefevre F., Lei R., Leitner R., Leung J., Li D., Li F., Li H., Li J., Li K., Li M., Li N., Li Q., Li R., Li S., Li T., Li W., Li X., Li Y., Li Z., Liang H., Liang J., Liebau D., Limphirat A., Limpijumnong S., Lin G.-L., Lin S., Lin T., Ling J., Lippi I., Liu F., Liu H., Liu J., Liu M., Liu Q., Liu R., Liu S., Liu X., Liu Y., Lokhov A., Lombardi P., Lombardo C., Loo K., Lu C., Lu H., Lu J., Lu S., Lu X., Lubsandorzhiev B., Lubsandorzhiev S., Ludhova L., Luo F., Luo G., Luo P., Luo S., Luo W., Lyashuk V., Ma Q., Ma S., Ma X., Maalmi J., Malyshkin Y., Mantovani F., Manzali F., Mao X., Mao Y., Mari S.M., Marini F., Marium S., Martellini C., Martin-Chassard G., Martini A., Mayilyan D., Muller A., Mednieks I., Meng Y., Meregaglia A., Meroni E., Meyhofer D., Mezzetto M., Miller J., Miramonti L., Monforte S., Montini P., Montuschi M., Morozov N., Muhammad W., Muralidharan P., Nastasi M., Naumov D.V., Naumova E., Navas-Nicolas D., Nemchenok I., Ning F., Ning Z., Nunokawa H., Oberauer L., Ochoa-Ricoux J.P., Olshevskiy A., Orestano D., Ortica F., Pan H.-R., Paoloni A., Parkalian N., Parmeggiano S., Payupol T., Pei Y., Pelliccia N., Peng A., Peng H., Perrot F., Petitjean P.-A., Petrucci F., Rico L.F.P., Pilarczyk O., Popov A., Poussot P., Pratumwan W., Previtali E., Qi F., Qi M., Qian S., Qian X., Qiao H., Qin Z., Qiu S., Rajput M., Ranucci G., Raper N., Re A., Rebber H., Rebii A., Ren B., Ren J., Rezinko T., Ricci B., Robens M., Roche M., Rodphai N., Romani A., Roskovec B., Roth C., Ruan X., Rujirawat S., Rybnikov A., Sadovsky A., Saggese P., Salamanna G., Sanfilippo S., Sangka A., Sanguansak N., Sawangwit U., Sawatzki J., Sawy F., Schever M., Schuler J., Schwab C., Schweizer K., Selivanov D., Selyunin A., Serafini A., Settanta G., Settimo M., Shao Z., Sharov V., Shi J., Shutov V., Sidorenkov A., Simkovic F., Sirignano C., Siripak J., Sisti M., Slupecki M., Smirnov M., Smirnov O., Sogo-Bezerra T., Songwadhana J., Soonthornthum B., Sotnikov A., Sramek O., Sreethawong W., Stahl A., Stanco L., Stankevich K., Stefanik D., Steiger H., Steinmann J., Sterr T., Stock M.R., Strati V., Studenikin A., Sun G., Sun S., Sun X., Sun Y., Suwonjandee N., Szelezniak M., Tang J., Tang Q., Tang X., Tietzsch A., Tkachev I., Tmej T., Treskov K., Triossi A., Troni G., Trzaska W., Tuve C., van Waasen S., van den Boom J., Vanroyen G., Vassilopoulos N., Vedin V., Verde G., Vialkov M., Viaud B., Volpe C., Vorobel V., Votano L., Walker P., Wang C., Wang C.-H., Wang E., Wang G., Wang J., Wang K., Wang L., Wang M., Wang R., Wang S., Wang W., Wang X., Wang Y., Wang Z., Watcharangkool A., Wei L., Wei W., Wei Y., Wen L., Wiebusch C., Wong S.C.-F., Wonsak B., Wu D., Wu F., Wu Q., Wu W., Wu Z., Wurm M., Wurtz J., Wysotzki C., Xi Y., Xia D., Xiao M., Xie Y., Xie Z., Xing Z., Xu B., Xu C., Xu D., Xu F., Xu J., Xu M., Xu Y., Yan B., Yan X., Yan Y., Yang A., Yang C., Yang H., Yang J., Yang L., Yang X., Yang Y., Yao H., Yasin Z., Ye J., Ye M., Ye Z., Yegin U., Yermia F., Yi P., Yin X., You Z., Yu B., Yu C., Yu H., Yu M., Yu X., Yu Z., Yuan C., Yuan Y., Yuan Z., Yue B., Zafar N., Zambanini A., Zeng S., Zeng T., Zeng Y., Zhan L., Zhang F., Zhang G., Zhang H., Zhang J., Zhang P., Zhang Q., Zhang S., Zhang T., Zhang X., Zhang Y., Zhang Z., Zhao F., Zhao J., Zhao R., Zhao S., Zhao T., Zheng D., Zheng H., Zheng M., Zheng Y., Zhong W., Zhou J., Zhou L., Zhou N., Zhou S., Zhou X., Zhu J., Zhu K., Zhuang H., Zong L., Zou J., Abusleme, A., Adam, T., Ahmad, S., Ahmed, R., Aiello, S., Akram, M., An, F., An, G., An, Q., Andronico, G., Anfimov, N., Antonelli, V., Antoshkina, T., Asavapibhop, B., de Andre, J. P. A. M., Auguste, D., Babic, A., Baldini, W., Barresi, A., Baussan, E., Bellato, M., Bergnoli, A., Bernieri, E., Birkenfeld, T., Blin, S., Blum, D., Blyth, S., Bolshakova, A., Bongrand, M., Bordereau, C., Breton, D., Brigatti, A., Brugnera, R., Bruno, R., Budano, A., Buscemi, M., Busto, J., Butorov, I., Cabrera, A., Cai, H., Cai, X., Cai, Y., Cai, Z., Cammi, A., Campeny, A., Cao, C., Cao, G., Cao, J., Caruso, R., Cerna, C., Chang, J., Chang, Y., Chen, P., Chen, P. -A., Chen, S., Chen, X., Chen, Y. -W., Chen, Y., Chen, Z., Cheng, J., Cheng, Y., Chiesa, D., Chimenti, P., Chukanov, A., Chuvashova, A., Claverie, G., Clementi, C., Clerbaux, B., Lorenzo, S. C. D., Corti, D., Costa, S., Corso, F. D., Dalager, O., Taille, C. D. L., Deng, J., Deng, Z., Depnering, W., Diaz, M., Ding, X., Ding, Y., Dirgantara, B., Dmitrievsky, S., Dohnal, T., Donchenko, G., Dong, J., Dornic, D., Doroshkevich, E., Dracos, M., Druillole, F., Du, S., Dusini, S., Dvorak, M., Enqvist, T., Enzmann, H., Fabbri, A., Fajt, L., Fan, D., Fan, L., Fang, C., Fang, J., Fargetta, M., Fatkina, A., Fedoseev, D., Fekete, V., Feng, L. -C., Feng, Q., Ford, R., Formozov, A., Fournier, A., Gan, H., Gao, F., Garfagnini, A., Gottel, A., Genster, C., Giammarchi, M., Giaz, A., Giudice, N., Giuliani, F., Gonchar, M., Gong, G., Gong, H., Gorchakov, O., Gornushkin, Y., Grassi, M., Grewing, C., Gromov, V., Gu, M., Gu, X., Gu, Y., Guan, M., Guardone, N., Gul, M., Guo, C., Guo, J., Guo, W., Guo, X., Guo, Y., Hackspacher, P., Hagner, C., Han, R., Han, Y., Hassan, M., He, M., He, W., Heinz, T., Hellmuth, P., Heng, Y., Herrera, R., Hong, D., Hor, Y., Hou, S., Hsiung, Y., Hu, B. -Z., Hu, H., Hu, J., Hu, S., Hu, T., Hu, Z., Huang, C., Huang, G., Huang, H., Huang, Q., Huang, W., Huang, X., Huang, Y., Hui, J., Huo, L., Huo, W., Huss, C., Hussain, S., Insolia, A., Ioannisian, A., Isocrate, R., Jelmini, B., Jen, K. -L., Ji, X., Jia, H., Jia, J., Jian, S., Jiang, D., Jiang, X., Jin, R., Jing, X., Jollet, C., Joutsenvaara, J., Jungthawan, S., Kalousis, L., Kampmann, P., Kang, L., Karagounis, M., Kazarian, N., Khan, A., Khan, W., Khosonthongkee, K., Kinz, P., Korablev, D., Kouzakov, K., Krasnoperov, A., Krokhaleva, S., Krumshteyn, Z., Kruth, A., Kutovskiy, N., Kuusiniemi, P., Lachenmaier, T., Landini, C., Leblanc, S., Lebrin, V., Lefevre, F., Lei, R., Leitner, R., Leung, J., Li, D., Li, F., Li, H., Li, J., Li, K., Li, M., Li, N., Li, Q., Li, R., Li, S., Li, T., Li, W., Li, X., Li, Y., Li, Z., Liang, H., Liang, J., Liebau, D., Limphirat, A., Limpijumnong, S., Lin, G. -L., Lin, S., Lin, T., Ling, J., Lippi, I., Liu, F., Liu, H., Liu, J., Liu, M., Liu, Q., Liu, R., Liu, S., Liu, X., Liu, Y., Lokhov, A., Lombardi, P., Lombardo, C., Loo, K., Lu, C., Lu, H., Lu, J., Lu, S., Lu, X., Lubsandorzhiev, B., Lubsandorzhiev, S., Ludhova, L., Luo, F., Luo, G., Luo, P., Luo, S., Luo, W., Lyashuk, V., Ma, Q., Ma, S., Ma, X., Maalmi, J., Malyshkin, Y., Mantovani, F., Manzali, F., Mao, X., Mao, Y., Mari, S. M., Marini, F., Marium, S., Martellini, C., Martin-Chassard, G., Martini, A., Mayilyan, D., Muller, A., Mednieks, I., Meng, Y., Meregaglia, A., Meroni, E., Meyhofer, D., Mezzetto, M., Miller, J., Miramonti, L., Monforte, S., Montini, P., Montuschi, M., Morozov, N., Muhammad, W., Muralidharan, P., Nastasi, M., Naumov, D. V., Naumova, E., Navas-Nicolas, D., Nemchenok, I., Ning, F., Ning, Z., Nunokawa, H., Oberauer, L., Ochoa-Ricoux, J. P., Olshevskiy, A., Orestano, D., Ortica, F., Pan, H. -R., Paoloni, A., Parkalian, N., Parmeggiano, S., Payupol, T., Pei, Y., Pelliccia, N., Peng, A., Peng, H., Perrot, F., Petitjean, P. -A., Petrucci, F., Rico, L. F. P., Pilarczyk, O., Popov, A., Poussot, P., Pratumwan, W., Previtali, E., Qi, F., Qi, M., Qian, S., Qian, X., Qiao, H., Qin, Z., Qiu, S., Rajput, M., Ranucci, G., Raper, N., Re, A., Rebber, H., Rebii, A., Ren, B., Ren, J., Rezinko, T., Ricci, B., Robens, M., Roche, M., Rodphai, N., Romani, A., Roskovec, B., Roth, C., Ruan, X., Rujirawat, S., Rybnikov, A., Sadovsky, A., Saggese, P., Salamanna, G., Sanfilippo, S., Sangka, A., Sanguansak, N., Sawangwit, U., Sawatzki, J., Sawy, F., Schever, M., Schuler, J., Schwab, C., Schweizer, K., Selivanov, D., Selyunin, A., Serafini, A., Settanta, G., Settimo, M., Shao, Z., Sharov, V., Shi, J., Shutov, V., Sidorenkov, A., Simkovic, F., Sirignano, C., Siripak, J., Sisti, M., Slupecki, M., Smirnov, M., Smirnov, O., Sogo-Bezerra, T., Songwadhana, J., Soonthornthum, B., Sotnikov, A., Sramek, O., Sreethawong, W., Stahl, A., Stanco, L., Stankevich, K., Stefanik, D., Steiger, H., Steinmann, J., Sterr, T., Stock, M. R., Strati, V., Studenikin, A., Sun, G., Sun, S., Sun, X., Sun, Y., Suwonjandee, N., Szelezniak, M., Tang, J., Tang, Q., Tang, X., Tietzsch, A., Tkachev, I., Tmej, T., Treskov, K., Triossi, A., Troni, G., Trzaska, W., Tuve, C., van Waasen, S., van den Boom, J., Vanroyen, G., Vassilopoulos, N., Vedin, V., Verde, G., Vialkov, M., Viaud, B., Volpe, C., Vorobel, V., Votano, L., Walker, P., Wang, C., Wang, C. -H., Wang, E., Wang, G., Wang, J., Wang, K., Wang, L., Wang, M., Wang, R., Wang, S., Wang, W., Wang, X., Wang, Y., Wang, Z., Watcharangkool, A., Wei, L., Wei, W., Wei, Y., Wen, L., Wiebusch, C., Wong, S. C. -F., Wonsak, B., Wu, D., Wu, F., Wu, Q., Wu, W., Wu, Z., Wurm, M., Wurtz, J., Wysotzki, C., Xi, Y., Xia, D., Xiao, M., Xie, Y., Xie, Z., Xing, Z., Xu, B., Xu, C., Xu, D., Xu, F., Xu, J., Xu, M., Xu, Y., Yan, B., Yan, X., Yan, Y., Yang, A., Yang, C., Yang, H., Yang, J., Yang, L., Yang, X., Yang, Y., Yao, H., Yasin, Z., Ye, J., Ye, M., Ye, Z., Yegin, U., Yermia, F., Yi, P., Yin, X., You, Z., Yu, B., Yu, C., Yu, H., Yu, M., Yu, X., Yu, Z., Yuan, C., Yuan, Y., Yuan, Z., Yue, B., Zafar, N., Zambanini, A., Zeng, S., Zeng, T., Zeng, Y., Zhan, L., Zhang, F., Zhang, G., Zhang, H., Zhang, J., Zhang, P., Zhang, Q., Zhang, S., Zhang, T., Zhang, X., Zhang, Y., Zhang, Z., Zhao, F., Zhao, J., Zhao, R., Zhao, S., Zhao, T., Zheng, D., Zheng, H., Zheng, M., Zheng, Y., Zhong, W., Zhou, J., Zhou, L., Zhou, N., Zhou, S., Zhou, X., Zhu, J., Zhu, K., Zhuang, H., Zong, L., and Zou, J.

Subjects
Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, measurement methods, scintillation counter: liquid, energy resolution, FOS: Physical sciences, Photodetector, Scintillator, 01 natural sciences, NO, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), hal-03022811, PE2_2, Optics, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Calibration, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, ddc:530, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Astrophysique, Jiangmen Underground Neutrino Observatory, Physics, JUNO, liquid [scintillation counter], 010308 nuclear & particles physics, business.industry, Settore FIS/01 - Fisica Sperimentale, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Linearity, Instrumentation and Detectors (physics.ins-det), calibration, Neutrino Detectors and Telescopes (experiments), lcsh:QC770-798, High Energy Physics::Experiment, Neutrino, business, Energy (signal processing)
Abstract

We present the calibration strategy for the 20 kton liquid scintillator central detector of the Jiangmen Underground Neutrino Observatory (JUNO). By utilizing a comprehensive multiple-source and multiple-positional calibration program, in combination with a novel dual calorimetry technique exploiting two independent photosensors and readout systems, we demonstrate that the JUNO central detector can achieve a better than 1% energy linearity and a 3% effective energy resolution, required by the neutrino mass ordering determination. [Figure not available: see fulltext.], 0, info:eu-repo/semantics/published

Published
2021

18. Renal Function, Cardiovascular Diseases, Appropriateness of Drug Prescription and Outcomes in Hospitalized Older Patients

Author

Antonietta, Gigante, Marco, Proietti, Enrico, Petrillo, Pier Mannuccio Mannucci, Alessandro, Nobili, Maurizio, Muscaritoli, Antonello, Pietrangelo, Francesco, Perticone, Francesco, Violi, Gino Roberto Corazza, Salvatore, Corrao, Alessandra, Marengoni, Francesco, Salerno, Matteo, Cesari, Mauro, Tettamanti, Luca, Pasina, Carlotta, Franchi, Laura, Cortesi, Gabriella, Miglio, Ilaria, Ardoino, Alessio, Novella, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Alessio, Molfino, Antonella, Giorgi, Christian, Gracian, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giorgio, Annoni, Maurizio, Corsi, Giuseppe, Bellelli, Alessandra, Bonfanti, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio, Brucato, Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Boari, Benedetta, DE GIORGI, Alfredo, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Ludovica, Perri, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Maria, Perticone, Rosa, Battaglia, Marco, Filice, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Silvia, Ghidoni, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, and Federica, Gandolfo.

Subjects
Drug, medicine.medical_specialty, Hospitalized patients, media_common.quotation_subject, Renal function, Socio-culturale, Kidney, Kidney Function Tests, Drug Prescriptions, Older patients, PEOPLE, Internal medicine, Atrial Fibrillation, Humans, Medicine, Pharmacology (medical), LS4_4, Medical prescription, Aged, media_common, CHRONIC KIDNEY DISEASE, POLYPHARMACY, FRAILTY POPULATION, PEOPLE, ADULTS, DEATH, business.industry, CHRONIC KIDNEY DISEASE, FRAILTY POPULATION, DEATH, ADULTS, Cardiovascular Diseases, Observational study, POLYPHARMACY, Geriatrics and Gerontology, business
Abstract

Reduced estimated creatinine clearance (eCrCl) is prevalent in older patients and impacts on drug prescription. In this study, the burden of eCrCl reduction and its associated factors and impact on outcomes were analyzed. Moreover, the rate of inappropriate drug prescription according to eCrCl and its impact on outcomes were described.Data were obtained from "REgistro POliterapie SIMI" (REPOSI), a prospective observational register enrolling hospitalized patients aged ≥ 65 years. Patients enrolled from 2010-2016 with available data to calculate eCrCl according to the Cockcroft-Gault formula were included in this analysis.A total of 5046 patients were available for analysis. Among these, we found an eCrCl of 45-59 mL/min in 1163 patients (23.0%), an eCrCl of 30-44 mL/min in 1128 (22.4%), an eCrCl of 15-29 mL/min in 702 (13.9%), and an eCrCl 15 mL/min in 152 (3.0%), with several clinical factors associated with decreasing eCrCl. During follow-up, a progressively higher risk for all-cause death, cardiovascular (CV) death, any death/re-hospitalization, and CV death/re-hospitalization was found across the renal function classes. Among patients with hypertension, diabetes mellitus, atrial fibrillation, coronary artery disease, and heart failure, 476 (10.9%) were inappropriately prescribed medications according to eCrCl. During follow-up, inappropriate prescription was associated with increased risk of all-cause death (odds ratio [OR] 1.49, 95% confidence interval [CI] 1.13-1.97) and any death/re-hospitalization (OR 1.30, 95% CI 1.03-1.63).In older hospitalized patients, impaired eCrCl is prevalent and associated with several factors, polypharmacy in particular. Patients with reduced eCrCl have a higher risk of major clinical outcomes, and 10% of them are prescribed an inappropriate drug, with a higher risk for major clinical outcomes.

Published
2021

19. Initiation of Psycholeptic Medication During Hospitalization With Recommendation for Discontinuation After Discharge

Author

Federica, Conti, Dario, Consonni, Sarah, Damanti, Alessandro, Nobili, Luca, Pasina, Pier Mannuccio Mannucci, Matteo, Cesari, Paolo Dionigi Rossi, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Lucia, Sofia, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Giuseppe, Zuccalà, Gabriella, D'Aurizio, Giuseppe, Romanelli, Alessandra, Marengoni, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio, Brucato, Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, DE GIORGI, Alfredo, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Francesco, Salerno, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Francesco, Violi, Ludovica, Perri, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Maria Angela Iseni, Silvia, Ghidoni, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, and Federica, Gandolfo.

Subjects
medicine.medical_specialty, Socio-culturale, Psycholeptic, 03 medical and health sciences, 0302 clinical medicine, delirium, deprescribing, medicine, Psycholeptics, Humans, 030212 general & internal medicine, LS4_4, Medical prescription, Cognitive decline, Risk factor, General Nursing, Aged, Retrospective Studies, business.industry, Health Policy, Retrospective cohort study, General Medicine, Length of Stay, Psycholeptics, delirium, dementia, deprescribing, hospitalization, older patients, older patients, Patient Discharge, Discontinuation, Hospitalization, Italy, Emergency medicine, Delirium, Geriatrics and Gerontology, medicine.symptom, Deprescribing, business, 030217 neurology & neurosurgery, dementia
Abstract

Objectives Psycholeptic drugs have been used in the older population for years, especially to control delirium and neuropsychiatric symptoms (NPS) of dementia. However, data from the literature confirm that the prolonged use of psycholeptics may be responsible for adverse reactions in older patients. The aim of this study was (1) to identify how many patients receive the first prescription of a psycholeptic drug during the hospital stay; (2) to evaluate the main sociodemographic and clinical characteristics of these patients; and (3) to verify if the prescribed psycholeptic drugs are continued after 3 months from the hospital discharge. Design Our retrospective study was based on data from the REPOSI (REgistro POliterapie SIMI) registry, a cohort of older patients hospitalized in internal medicine and geriatric wards throughout Italy from 2010 to 2018. Setting and Participants Patients aged 65 years or older who were not on home therapy with psycholeptic drugs were considered in the analyses. Methods We did both univariate and multivariate analyses in order to find the variables associated independently to an increased risk for first psycholeptic prescription at hospital discharge. Results At hospital discharge, 193 patients (5.8%) out of a total sample of 3322 patients were prescribed at least 1 psycholeptic drug. Cognitive impairment was the main risk factor for the introduction of psycholeptic drugs at discharge. Among them, 89.1% were still on therapy with a psycholeptic drug after 3 months from the hospital discharge. Conclusions and Implications Cognitive impairment represents the main risk factor for psycholeptic initiation in hospitalized older patients. The vast majority of these treatments are chronically continued after the discharge. Therefore, special attention is needed in prescribing psycholeptics at discharge, because their prolonged use may lead to cognitive decline. Moreover, their continued use should be questioned by physicians providing post-acute care, and deprescribing should be considered.

Published
2021

20. The POEMMA (Probe of Extreme Multi-Messenger Astrophysics) observatory

Author

Patrick J. Reardon, P. Bertone, A. Anzalone, Y. Takizawa, Kevin-Druis Merenda, Ke Fang, S. Mackovjak, M. Bagheri, Roberto Aloisio, M. E. Bertaina, S. S. Meyer, G. Filippatos, Ralf Ulrich, D. Barghini, Douglas Bergman, Jane Nachtman, Yasar Onel, Fred Sarazin, R. Young, E. G. Judd, Mark Christl, D. Winn, K. Shinozaki, Angela V. Olinto, Miroslav Pech, P. Picozza, L. Marcelli, E. Hays, G. Prévôt, M. Battisti, Dusan Mandat, Floyd W. Stecker, F. Oikonomou, Z. Plebaniak, A. Haungs, Jorge F. Soriano, Ralph Engel, A. N. Otte, John Mitchell, Francesco Fenu, Johannes Eser, Mauricio Bustamante, Petr Schovanek, Eliza Gazda, M. Ricci, Mikhail Zotov, Rossella Caruso, Andrii Neronov, E. Parizot, Luis A. Anchordoqui, Valentina Scotti, V. Kungel, A. L. Cummings, F. Cafagna, Pavel Klimov, Marco Casolino, James H. Adams, C. Guepin, G. Osteria, E. Kuznetsov, O. Romero Matamala, I. De Mitri, K. Černý, J. S. Perkins, Tonia M. Venters, R. Diesing, T. Paul, L. R. Wiencke, G. Medina-Tanco, Mary Hall Reno, John F. Krizmanic, H. Miyamoto, Lech Wiktor Piotrowski, Julie McEnery, Francesca Bisconti, M. Unger, Collaboration, P., Olinto, A. V., Krizmanic, J., Adams, J. H., Aloisio, R., Anchordoqui, L. A., Anzalone, A., Bagheri, M., Barghini, D., Battisti, M., Bergman, D. R., Bertaina, M. E., Bertone, P. F., Bisconti, F., Bustamante, M., Cafagna, F., Caruso, R., Casolino, M., Cerny, K., Christl, M. J., Cummings, A. L., De Mitri, I., Diesing, R., Engel, R., Eser, J., Fang, K., Fenu, F., Filippatos, G., Gazda, E., Guepin, C., Haungs, A., Hays, E. A., Judd, E. G., Klimov, P., Kungel, V., Kuznetsov, E., Mackovjak, S., Mandat, D., Marcelli, L., Mcenery, J., Medina-Tanco, G., Merenda, K. -D., Meyer, S. S., Mitchell, J. W., Miyamoto, H., Nachtman, J. M., Neronov, A., Oikonomou, F., Onel, Y., Osteria, G., Otte, A. N., Parizot, E., Paul, T., Pech, M., Perkins, J. S., Picozza, P., Piotrowski, L. W., Plebaniak, Z., Prevot, G., Reardon, P., Reno, M. H., Ricci, M., Romero Matamala, O., Sarazin, F., Schovanek, P., Scotti, V., Shinozaki, K., Soriano, J. F., Stecker, F., Takizawa, Y., Ulrich, R., Unger, M., Venters, T. M., Wiencke, L., Winn, D., Young, R. M., Zotov, M., AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), POEMMA, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)

Subjects
air: fluorescence, cosmic rays detectors, neutrino astronomy, ultra high energy cosmic rays, ultra high energy photons and neutrinos, Astrophysics, 7. Clean energy, 01 natural sciences, neutrino: flux, ultra high energy cosmic ray, law.invention, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Observatory, law, ultraviolet, optical, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Cherenkov, orbit, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), COSMIC cancer database, formation, Astrophysics::Instrumentation and Methods for Astrophysics, Schmidt camera, neutrino: UHE, observatory, Neutrino, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics::High Energy Astrophysical Phenomena, satellite, FOS: Physical sciences, Cosmic ray, Telescope, 0103 physical sciences, cosmic radiation: UHE, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], cosmic rays detector, Instrumentation and Methods for Astrophysics (astro-ph.IM), Cherenkov radiation, neutrino/tau, showers: atmosphere, hybrid, 010308 nuclear & particles physics, detector: surface, Astronomy and Astrophysics, neutrino: particle source, sensitivity, messenger, 13. Climate action, Neutrino astronomy, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract

The Probe Of Extreme Multi-Messenger Astrophysics (POEMMA) is designed to accurately observe ultra-high-energy cosmic rays (UHECRs) and cosmic neutrinos from space with sensitivity over the full celestial sky. POEMMA will observe the extensive air showers (EASs) from UHECRs and UHE neutrinos above 20 EeV via air fluorescence. Additionally, POEMMA will observe the Cherenkov signal from upward-moving EASs induced by Earth-interacting tau neutrinos above 20 PeV. The POEMMA spacecraft are designed to quickly re-orientate to follow up transient neutrino sources and obtain unparalleled neutrino flux sensitivity. Developed as a NASA Astrophysics Probe-class mission, POEMMA consists of two identical satellites flying in loose formation in 525 km altitude orbits. Each POEMMA instrument incorporates a wide field-of-view (45$^\circ$) Schmidt telescope with over 6 m$^2$ of collecting area. The hybrid focal surface of each telescope includes a fast (1~$\mu$s) near-ultraviolet camera for EAS fluorescence observations and an ultrafast (10~ns) optical camera for Cherenkov EAS observations. In a 5-year mission, POEMMA will provide measurements that open new multi-messenger windows onto the most energetic events in the universe, enabling the study of new astrophysics and particle physics at these otherwise inaccessible energies., Comment: 66 pages, 53 figures; JCAP accepted version

Published
2021

21. Use of Lipid-Lowering Drugs and Associated Outcomes According to Health State Profiles in Hospitalized Older Patients

Author

Carlotta, Franchi, Giulia, Lancellotti, Marco, Bertolotti, Simona Di Salvatore, Alessandro, Nobili, Pier Mannuccio Mannucci, Chiara, Mussi, Ilaria, Ardoino, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Model, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Matteo, Cesari, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Alessandra, Marengoni, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio Brucato Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, DE GIORGI, Alfredo, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Francesco, Salerno, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Francesco, Violi, Ludovica, Perri, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Silvia, Ghidoni, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, and Federica, Gandolfo.

Subjects
Male, multimorbidity, Health state profile, Frail Elderly, Health Status, Socio-culturale, Comorbidity, statins, Cognition, 80 and over, Prevalence, Humans, LS4_4, polypharmacy, Aged, Hypolipidemic Agents, Retrospective Studies, Original Research, Aged, 80 and over, Frailty, Statins, RC952-954.6, Multimorbidity, health state profile, Lipids, health state profile, multimorbidity, polypharmacy, statins, Hospitalization, Logistic Models, Italy, Socioeconomic Factors, Polypharmacy, Guideline Adherence, Practice Guidelines as Topic, Geriatrics, Clinical Interventions in Aging
Abstract

Carlotta Franchi,1 Giulia Lancellotti,2 Marco Bertolotti,2 Simona Di Salvatore,2 Alessandro Nobili,1 Pier Mannuccio Mannucci,3 Chiara Mussi,2,&ast; Ilaria Ardoino1,&ast; On Behalf of the REPOSI (REgistro POliterapie SIMI and Società Italiana di Medicina Interna) Study Group1Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy; 2Division of Geriatrics, Department of Biomedical, metabolic and Neural Sciences and Center for Gerontological Evaluation and Research, Università di Modena e Reggio Emilia, Modena, Italy; 3Scientific Direction, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy&ast;These authors contributed equally to this workCorrespondence: Carlotta FranchiUnit of Pharmacoepidemiological Research in Older People, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milano, 20156, ItalyTel +39 02 39014580Fax +39 02 39001916Email carlotta.franchi@marionegri.itObjective: To assess how lipid-lowering drugs (LLDs) are administered in the hospitalized patients aged 65 and older and their association with clinical outcomes according to their health-related profiles.Design: This is a retrospective study based on data from REPOSI (REgistro POliterapie SIMI – Italian Society of Internal Medicine) register, an Italian network of internal medicine hospital wards.Setting and Participants: A total of 4642 patients with a mean age of 79 years enrolled between 2010 and 2018.Methods: Socio-demographic characteristics, functional abilities, cognitive skills, laboratory parameters and comorbidities were used to investigate the health state profiles by using multiple correspondence analysis and clustering. Logistic regression was used to assess whether LLD prescription was associated with patients’ health state profiles and with short-term mortality.Results: Four clusters of patients were identified according to their health state: two of them (Cluster III and IV) were the epitome of frailty conditions with poor short-term outcomes, whereas the others included healthier patients. The average prevalence of LLD use was 27.6%. The lowest prevalence was found among the healthier patients in Cluster I and among the oldest frail patients with severe functional and cognitive impairment in Cluster IV. The highest prevalence was among multimorbid patients in Cluster III (OR=4.50, 95% CI=3.76– 5.38) characterized by a high cardiovascular risk. Being prescribed with LLDs was associated with a lower 3-month mortality, even after adjusting for cluster assignment (OR=0.59; 95% CI = 0.44– 0.80).Conclusion: The prevalence of LLD prescription was low and in overall agreement with guideline recommendations and with respect to patients’ health state profiles.Keywords: statins, health state profile, multimorbidity, polypharmacy

Published
2021

22. Measurement of the Fluctuations in the Number of Muons in Extensive Air Showers with the Pierre Auger Observatory

Author

H. J. Mathes, Stanislav Michal, Miroslav Pech, Antonio Condorelli, M. Pothast, Pavel Horvath, A.L. Garcia Vegas, W. M. Namasaka, A. C. Rovero, M. Risse, J. Rodriguez Rojo, Fridtjof Feldbusch, B. Andrada, Alexandru Balaceanu, Jonathan Blazek, Carla Aramo, Vincenzo Rizi, J. F. Valdés Galicia, Julien Souchard, Sofia Andringa, Enrique Zas, Magdalena Cerdá, Hernán Asorey, I. De Mitri, D. Martello, David Wittkowski, O. Martínez Bravo, K. Mulrey, P. Abreu, D. Ravignani, G. Salina, Danielle LaHurd, Olivier Deligny, Marcel Köpke, M. Platino, Fernando Contreras, A. Tapia, H. Gemmeke, G. Parente, Fabrizia Canfora, L. Zehrer, L. Lopes, Tomáš Fodran, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, M. A. Leigui de Oliveira, Flavia Gesualdi, G. Kukec Mezek, G. Marsella, Valerio Pirronello, R. Lorek, G. De Mauro, M. Unger, Ugo Giaccari, Silvia Mollerach, H. Dembinski, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, Dariusz Gora, M. E. Bertaina, Jon Paul Lundquist, A. Menshikov, K.-H. Becker, M. Pimenta, P.R. Araújo Ferreira, J. de Oliveira, Alejandro Almela, C. J. Todero Peixoto, M. Zavrtanik, Lukáš Vaclavek, W. Rodrigues de Carvalho, Jörg R. Hörandel, B. Keilhauer, Marcus Niechciol, A. C. Fauth, Teresa Bister, J. Chudoba, Alan Coleman, B. Tome, Josina Schulte, S. J. Saffi, Tobias Winchen, Julian Kemp, S. J. Sciutto, Carla Bleve, Rodrigo Guedes Lang, Florian Lukas Briechle, Peter Hansen, Lorenzo Caccianiga, Marvin Gottowik, Julien Manshanden, G. Cataldi, E. De Vito, F. Guarino, John Matthews, I. Lhenry-Yvon, Nataliia Borodai, V. Scherini, Paul Sommers, Peter Buchholz, Andres Travaini, Giovanni Consolati, E. Varela, J.D. Sanabria Gomez, Juan Miguel Carceller, Christian Sarmiento-Cano, R. M. de Almeida, P. Tobiska, Alex Kääpä, F. Pedreira, Carla Bonifazi, D. Lo Presti, Jose A. Bellido, S. J. De Jong, Marco Aglietta, Vladimir Lenok, Eric Mayotte, Raul Sarmento, Fabio Convenga, M. M. Freire, Felix Schlüter, H. Wilczyński, Jeffrey A. Johnsen, Fabian Gobbi, Jose Chinellato, F. Sánchez, Serguei Vorobiov, L. Perrone, Alena Bakalova, E. M. Santos, D. Nitz, R. Squartini, Alfred Müller, Petr Schovanek, Valerio Verzi, A. Fuster, G. Golup, M. Gómez Berisso, R. C. Shellard, Octavian Sima, Jarryd A. Day, A. Saftoiu, A.C. Cobos Cerutti, J. R. T. de Mello Neto, G. Torralba Elipe, R. Alves Batista, Bruce R. Dawson, G. Matthiae, Jesús Peña-Rodríguez, Antonio Bueno, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, H. Schieler, Antonella Castellina, Maria Rita Coluccia, A. Di Matteo, M. Schimp, B. Wundheiler, B. C. Manning, A. Insolia, M. Kleifges, D. Zavrtanik, A.D. Supanitsky, Fred Sarazin, J. Pȩkala, Ioana Caracas, A. Letessier-Selvon, B. García, R. López, Karen S. Caballero-Mora, P.O. Mazur, Thomas Bretz, Lorenzo Cazon, Darko Veberič, Mario Buscemi, Roberto Mussa, T. Huege, I.D. Vergara Quispe, G. Medina-Tanco, R. Halliday, L. Valore, J. Rautenberg, Jeffrey Brack, Günter Sigl, Olaf Scholten, F. Riehn, Marina Scornavacche, Corbin Covault, Jonathan Biteau, Francesco Fenu, Xavier Bertou, Humberto Ibarguen Salazar, L. R. Wiencke, Rodrigo Pelayo, Stijn Buitink, Niklas Langner, S. Querchfeld, Olena Tkachenko, J. Šupík, Carlo Ventura, Gualberto Avila, Q. Luce, M. Suárez-Durán, Maximilian Reininghaus, A. Zepeda, Brian Fick, Nicolás González, P. Stassi, Ladislav Chytka, Lino Miramonti, Ioana Codrina Maris, Pedro Assis, François Montanet, Radomir Smida, A. Machado Payeras, Martin Erdmann, J. de Jesús, H. Martinez, A. Etchegoyen, Maximilian Stadelmaier, Sullivan Marafico, Miguel Mostafa, P. Ruehl, D. de Oliveira Franco, A. Streich, Gioacchino Alex Anastasi, Dusan Mandat, J. Stasielak, J. Hulsman, J. Kleinfeller, G. C. Hill, Marco Giammarchi, M. Wirtz, Frank G. Schröder, Eleonora Guido, Roger W Clay, Jorge F. Soriano, Ralph Engel, Denis Stanca, C. M. Schäfer, Fernando Gollan, Massimo Mastrodicasa, Hernan Wahlberg, L. Nellen, Carlos Escobar, Kevin-Druis Merenda, Samo Stanič, K. H. Kampert, J. Ridky, R.J. Barreira Luz, Martin Vacula, John Farmer, C. Morello, Heino Falcke, A. Puyleart, V. de Souza, R. Conceição, Miroslav Hrabovský, Corinne Berat, M. Giller, Isabel Goos, Luis A. Anchordoqui, A. Parra, J. Perez Armand, Kai Daumiller, D. Heck, Maria-Teresa Dova, M. R. Hampel, J. Vicha, A. Haungs, L. Bonneau Arbeletche, Peter L. Biermann, Philipp Papenbreer, M. Schimassek, M. del Río, C. Hojvat, Petr Travnicek, Jan Ebr, Claudio Galelli, Denise Boncioli, Trent D. Grubb, Paolo Privitera, P. Ristori, Jacco Vink, M. Trini, H.O. Klages, M. A. Muller, Markus Roth, Juan Manuel Figueira, Roberta Colalillo, A. G. Mariazzi, P. Savina, A. Aab, A. A. Nucita, Ralf Ulrich, Martina Bohacova, M. I. Micheletti, B. L. Lago, R.C. dos Anjos, Adriana Vásquez-Ramírez, Giovanni Mancarella, Juan Pablo Gongora, M. Palatka, P. Mantsch, A. Cancio, Z. Szadkowski, Matias Tueros, Luis A. Nunez, Paula Gina Isar, F. Salamida, V. Novotny, I. Allekotte, M. J. Roncoroni, Rossella Caruso, A. Lucero, Fernando Catalani, T. Suomijärvi, Caterina Trimarelli, A. Yushkov, D. Melo, D. Nosek, E. Santos, R. Sato, J. Pallotta, A. M. Botti, Niraj Dhital, I. Valiño, G. P. Guedes, Alessio Gorgi, A. Weindl, L. Nožka, Toshihiro Fujii, Orazio Zapparrata, Jakub Juryšek, J. Debatin, Carola Dobrigkeit, M. Muzio, Steffen Hahn, Juan Carlos D'Olivo, T. Pierog, Esteban Roulet, Justin M. Albury, Alan Watson, David Schmidt, S. Schröder, Italo Epicoco, M. Perlin, Mihai Niculescu-Oglinzanu, Piera Luisa Ghia, G. Farrar, A. Taboada, P.F. Gómez Vitale, Violet M. Harvey, D. Harari, Alina Mihaela Badescu, Cristina Galea, M. Prouza, Gaia Silli, A. Filipčič, S. Petrera, Marc Weber, Bjarni Pont, C. J.W.P. Timmermans, K. Choi, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Aab, A, Abreu, P, Aglietta, M, Albury, J M, Allekotte, I, Almela, A, Alvarez-Muñiz, J, Alves Batista, R, Anastasi, G A, Anchordoqui, L, Andrada, B, Andringa, S, Aramo, C, Araújo Ferreira, P R, Asorey, H, Assis, P, Avila, G, Badescu, A M, Bakalova, A, Balaceanu, A, Barbato, F, Barreira Luz, R J, Becker, K H, Bellido, J A, Berat, C, Bertaina, M E, Bertou, X, Biermann, P L, Bister, T, Biteau, J, Blazek, J, Bleve, C, Boháčová, M, Boncioli, D, Bonifazi, C, Bonneau Arbeletche, L, Borodai, N, Botti, A M, Brack, J, Bretz, T, Briechle, F L, Buchholz, P, Bueno, A, Buitink, S, Buscemi, M, Caballero-Mora, K S, Caccianiga, L, Cancio, A, Canfora, F, Caracas, I, Carceller, J M, Caruso, R, Castellina, A, Catalani, F, Cataldi, G, Cazon, L, Cerda, M, Chinellato, J A, Choi, K, Chudoba, J, Chytka, L, Clay, R W, Cobos Cerutti, A C, Colalillo, R, Coleman, A, Coluccia, M R, Conceição, R, Condorelli, A, Consolati, G, Contreras, F, Convenga, F, Covault, C E, Dasso, S, Daumiller, K, Dawson, B R, Day, J A, de Almeida, R M, de Jesús, J, de Jong, S J, De Mauro, G, de Mello Neto, J R T, De Mitri, I, de Oliveira, J, de Oliveira Franco, D, de Souza, V, De Vito, E, Debatin, J, Del Río, M, Deligny, O, Dembinski, H, Dhital, N, Di Matteo, A, Dobrigkeit, C, D'Olivo, J C, Dos Anjos, R C, Dova, M T, Ebr, J, Engel, R, Epicoco, I, Erdmann, M, Escobar, C O, Etchegoyen, A, Falcke, H, Farmer, J, Farrar, G, Fauth, A C, Fazzini, N, Feldbusch, F, Fenu, F, Fick, B, Figueira, J M, Filipčič, A, Fodran, T, Freire, M M, Fujii, T, Fuster, A, Galea, C, Galelli, C, García, B, Garcia Vegas, A L, Gemmeke, H, Gesualdi, F, Gherghel-Lascu, A, Ghia, P L, Giaccari, U, Giammarchi, M, Giller, M, Glombitza, J, Gobbi, F, Gollan, F, Golup, G, Gómez Berisso, M, Gómez Vitale, P F, Gongora, J P, González, N, Goos, I, Góra, D, Gorgi, A, Gottowik, M, Grubb, T D, Guarino, F, Guedes, G P, Guido, E, Hahn, S, Halliday, R, Hampel, M R, Hansen, P, Harari, D, Harvey, V M, Haungs, A, Hebbeker, T, Heck, D, Hill, G C, Hojvat, C, Hörandel, J R, Horvath, P, Hrabovský, M, Huege, T, Hulsman, J, Insolia, A, Isar, P G, Johnsen, J A, Jurysek, J, Kääpä, A, Kampert, K H, Keilhauer, B, Kemp, J, Klages, H O, Kleifges, M, Kleinfeller, J, Köpke, M, Kukec Mezek, G, Lago, B L, Lahurd, D, Lang, R G, Langner, N, Leigui de Oliveira, M A, Lenok, V, Letessier-Selvon, A, Lhenry-Yvon, I, Lo Presti, D, Lopes, L, López, R, Lorek, R, Luce, Q, Lucero, A, Lundquist, J P, Machado Payeras, A, Mancarella, G, Mandat, D, Manning, B C, Manshanden, J, Mantsch, P, Marafico, S, Mariazzi, A G, Mariş, I C, Marsella, G, Martello, D, Martinez, H, Martínez Bravo, O, Mastrodicasa, M, Mathes, H J, Matthews, J, Matthiae, G, Mayotte, E, Mazur, P O, Medina-Tanco, G, Melo, D, Menshikov, A, Merenda, K-D, Michal, S, Micheletti, M I, Miramonti, L, Mollerach, S, Montanet, F, Morello, C, Mostafá, M, Müller, A L, Muller, M A, Mulrey, K, Mussa, R, Muzio, M, Namasaka, W M, Nellen, L, Niculescu-Oglinzanu, M, Niechciol, M, Nitz, D, Nosek, D, Novotny, V, Nožka, L, Nucita, A, Núñez, L A, Palatka, M, Pallotta, J, Papenbreer, P, Parente, G, Parra, A, Pech, M, Pedreira, F, Pȩkala, J, Pelayo, R, Peña-Rodriguez, J, Perez Armand, J, Perlin, M, Perrone, L, Petrera, S, Pierog, T, Pimenta, M, Pirronello, V, Platino, M, Pont, B, Pothast, M, Privitera, P, Prouza, M, Puyleart, A, Querchfeld, S, Rautenberg, J, Ravignani, D, Reininghaus, M, Ridky, J, Riehn, F, Risse, M, Ristori, P, Rizi, V, Rodrigues de Carvalho, W, Rodriguez Rojo, J, Roncoroni, M J, Roth, M, Roulet, E, Rovero, A C, Ruehl, P, Saffi, S J, Saftoiu, A, Salamida, F, Salazar, H, Salina, G, Sanabria Gomez, J D, Sánchez, F, Santos, E M, Santos, E, Sarazin, F, Sarmento, R, Sarmiento-Cano, C, Sato, R, Savina, P, Schäfer, C M, Scherini, V, Schieler, H, Schimassek, M, Schimp, M, Schlüter, F, Schmidt, D, Scholten, O, Schovánek, P, Schröder, F G, Schröder, S, Schulte, J, Sciutto, S J, Scornavacche, M, Shellard, R C, Sigl, G, Silli, G, Sima, O, Šmída, R, Sommers, P, Soriano, J F, Souchard, J, Squartini, R, Stadelmaier, M, Stanca, D, Stanič, S, Stasielak, J, Stassi, P, Streich, A, Suárez-Durán, M, Sudholz, T, Suomijärvi, T, Supanitsky, A D, Šupík, J, Szadkowski, Z, Taboada, A, Tapia, A, Timmermans, C, Tkachenko, O, Tobiska, P, Todero Peixoto, C J, Tomé, B, Torralba Elipe, G, Travaini, A, Travnicek, P, Trimarelli, C, Trini, M, Tueros, M, Ulrich, R, Unger, M, Vaclavek, L, Vacula, M, Valdés Galicia, J F, Valiño, I, Valore, L, Varela, E, Varma K C, V, Vásquez-Ramírez, A, Veberič, D, Ventura, C, Vergara Quispe, I D, Verzi, V, Vicha, J, Vink, J, Vorobiov, S, Wahlberg, H, Watson, A A, Weber, M, Weindl, A, Wiencke, L, Wilczyński, H, Winchen, T, Wirtz, M, Wittkowski, D, Wundheiler, B, Yushkov, A, Zapparrata, O, Zas, E, Zavrtanik, D, Zavrtanik, M, Zehrer, L, Zepeda, A, High Energy Astrophys. & Astropart. Phys (API, FNWI), Gravitation and Astroparticle Physics Amsterdam, Physics, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Muniz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Araujo Ferreira, P. R., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Cancio, A., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., De Almeida, R. M., De Jesus, J., De Jong, S. J., De Mauro, G., De Mello Neto, J. R. T., De Mitri, I., De Oliveira, J., De Oliveira Franco, D., De Souza, V., De Vito, E., Debatin, J., Del Rio, M., Deligny, O., Dembinski, H., Dhital, N., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., Dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Gomez Berisso, M., Gomez Vitale, P. F., Gongora, J. P., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Halliday, R., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Kukec Mezek, G., Lago, B. L., Lahurd, D., Lang, R. G., Langner, N., Leigui De Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Lorek, R., Luce, Q., Lucero, A., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Martinez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nunez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pkala, J., Pelayo, R., Pena-Rodriguez, J., Perez Armand, J., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Ristori, P., Rizi, V., Rodrigues De Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Tapia, A., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tome, B., Torralba Elipe, G., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Valdes Galicia, J. F., Valino, I., Valore, L., Varela, E., Varma, K. C. V., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Astronomy, Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Alves Batista R., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Araujo Ferreira P.R., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Bonneau Arbeletche L., Borodai N., Botti A.M., Brack J., Bretz T., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Cancio A., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., De Almeida R.M., De Jesus J., De Jong S.J., De Mauro G., De Mello Neto J.R.T., De Mitri I., De Oliveira J., De Oliveira Franco D., De Souza V., De Vito E., Debatin J., Del Rio M., Deligny O., Dembinski H., Dhital N., Di Matteo A., Dobrigkeit C., D'Olivo J.C., Dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Garcia Vegas A.L., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Halliday R., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kukec Mezek G., Lago B.L., Lahurd D., Lang R.G., Langner N., Leigui De Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Lorek R., Luce Q., Lucero A., Lundquist J.P., Machado Payeras A., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., NoZka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pkala J., Pelayo R., Pena-Rodriguez J., Perez Armand J., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Ristori P., Rizi V., Rodrigues De Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Timmermans C., Tkachenko O., Tobiska P., Todero Peixoto C.J., Tome B., Torralba Elipe G., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Valdes Galicia J.F., Valino I., Valore L., Varela E., Varma K. C. V., Vasquez-Ramirez A., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., and Zepeda A.

Subjects
interaction: model, Physics::Instrumentation and Detectors, Astronomy, Hadron, General Physics and Astronomy, Ultra-high energy cosmic rays, muons properties, hadronic models, 01 natural sciences, cosmic ray, particle interaction, astroparticle detectors, Auger, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), iron, surface [detector], Observatory, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Physics, 4. Education, Settore FIS/01 - Fisica Sperimentale, measured [fluctuation], model [interaction], Astrophysics::Instrumentation and Methods for Astrophysics, model: hadronic, fluctuation: measured, 3. Good health, observatory, Sciences exactes et naturelles, atmosphere [showers], model [particle], air, Cherenkov counter: water, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], FOS: Physical sciences, Cosmic ray, detector: fluorescence, Nuclear physics, cosmic rays, muon, 0103 physical sciences, calorimeter, ddc:530, 14. Life underwater, cosmic radiation: UHE, High Energy Physics, distribution function, electromagnetic component, 010306 general physics, Astrophysique, Pierre Auger Observatory, fluorescence [detector], Muon, showers: atmosphere, hep-ex, detector: surface, water [Cherenkov counter], particle: model, Small deviations, Física, ASTROFÍSICA, Air shower, Experimental High Energy Physics, Elementary Particles and Fields, hadronic [model], High Energy Physics::Experiment
Abstract

The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargue. We are very grateful to the following agencies and organizations for financial support: Argentina-Comision Nacional de Energia Atomica, Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT), Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Gobierno de la Provincia de Mendoza, Municipalidad de Malargue, NDM Holdings and Valle Las Lenas; in gratitude for their continuing cooperation over land access; Australia-the Australian Research Council; BrazilConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Financiadora de Estudos e Projetos (FINEP), Fundacao de Amparo a Pesquisa do Estado de Rio de Janeiro (FAPERJ), Sao Paulo Research Foundation (FAPESP) Grants No. 2019/10151-2, No. 2010/07359-6, and No. 1999/05404-3, Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC); Ministry of Education, Youth and Sports of the Czech RepublicGrants No. MSMT CR LTT18004, No. LM2015038, No. LM2018102, No. CZ.02.1.01/0.0/0.0/16_013/0001402, No. CZ.02.1.01/0.0/0.0/18_046/0016010, and No. CZ.02.1.01/0.0/0.0/17_049/0008422; France-Centre de Calcul IN2P3/CNRS, Centre National de la Recherche Scientifique (CNRS), Conseil Regional Ile-de-France, Departement Physique Nucl ' eaire et Corpusculaire (PNC-IN2P3/CNRS), Departement Sciences de l'Univers (SDU-INSU/CNRS), Institut Lagrange de Paris (ILP) Grant No. LABEX ANR-10-LABX-63 within the Investissements d'Avenir Programme Grant No. ANR11-IDEX-0004-02; Germany-Bundesministerium fur Bildung und Forschung (BMBF), Deutsche Forschungsgemeinschaft (DFG), Finanzministerium Baden-Wurttemberg, Helmholtz Alliance for Astroparticle Physics (HAP), Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF), Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg; Italy-Istituto Nazionale di Fisica Nucleare (INFN), Istituto Nazionale di Astrofisica (INAF), Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), CETEMPS Center of Excellence, Ministero degli Affari Esteri (MAE); Mexico-Consejo Nacional de Ciencia y Tecnologia (CONACYT) Grant No. 167733, Universidad Nacional Autonoma de Mexico (UNAM), PAPIIT DGAPA-UNAM; The Netherlands-Ministry of Education, Culture and Science, Netherlands Organisation for Scientific Research (NWO), Dutch national e-infrastructure with the support of SURF Cooperative; Poland-Ministry of Science and Higher Education, Grant No. DIR/WK/2018/11, National Science Centre, Grants No. 2013/08/M/ST9/00322, No. 2016/23/B/ST9/01635, and No. HARMONIA 5-2013/10/M/ST9/00062, UMO-2016/22/M/ST9/00198; Portugal -Portuguese national funds and FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE); Romania-Romanian Ministry of Education and Research, the Program Nucleu within MCI (PN19150201/16N/2019 and PN19060102), and project PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018 within PNCDI III; Slovenia-Slovenian Research Agency, Grants No. P1-0031, No. P1-0385, No. I00033, No. N1-0111; Spain-Ministerio de Economia, Industria y Competitividad (FPA2017-85114-P and FPA2017-85197-P), Xunta de Galicia (ED431C 2017/07), Junta de Andalucia (SOMM17/6104/UGR), Feder Funds, RENATA Red Nacional Tematica de Astroparticulas (FPA2015-68783-REDT), and Maria de Maeztu Unit of Excellence (MDM-2016-0692); U.S.Department of Energy, Awards No. DE-AC0207CH11359, No. DE-FR02-04ER41300, No. DE-FG0299ER41107, and No. DE-SC0011689, National Science Foundation, Grant No. 0450696, The Grainger Foundation, Marie Curie-IRSES/EPLANET, European Particle Physics Latin American Network, and UNESCO., We present the first measurement of the fluctuations in the number of muons in extensive air showers produced by ultrahigh energy cosmic rays. We find that the measured fluctuations are in good agreement with predictions from air shower simulations. This observation provides new insights into the origin of the previously reported deficit of muons in air shower simulations and constrains models of hadronic interactions at ultrahigh energies. Our measurement is compatible with the muon deficit originating from small deviations in the predictions from hadronic interaction models of particle production that accumulate as the showers develop., Argentina-Comision Nacional de Energia Atomica, ANPCyT, Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Gobierno de la Provincia de Mendoza, Municipalidad de Malargue, NDM Holdings, Valle Las Lenas, Australian Research Council, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ), Fundacao de Apoio a Pesquisa do Distrito Federal (FAPDF), Financiadora de Inovacao e Pesquisa (Finep), Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio De Janeiro (FAPERJ), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) 2019/10151-2 2010/07359-6 1999/05404-3, Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC), Ministry of Education, Youth & Sports - Czech Republic MSMT CR LTT18004 LM2015038 LM2018102 CZ.02.1.01/0.0/0.0/16_013/0001402 CZ.02.1.01/0.0/0.0/18_046/0016010 CZ.02.1.01/0.0/0.0/17_049/0008422, France-Centre de Calcul IN2P3/CNRS, Centre National de la Recherche Scientifique (CNRS), Region Ile-de-France, Departement Sciences de l'Univers (SDU-INSU/CNRS), French National Research Agency (ANR) LABEX ANR-10-LABX-63 ANR11-IDEX-0004-02, Federal Ministry of Education & Research (BMBF), German Research Foundation (DFG), Finanzministerium Baden-Wurttemberg, Helmholtz Alliance for Astroparticle Physics (HAP), Helmholtz Association, Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg, Italy-Istituto Nazionale di Fisica Nucleare (INFN), Istituto Nazionale Astrofisica (INAF), Ministry of Education, Universities and Research (MIUR), CETEMPS Center of Excellence, Ministry of Foreign Affairs and International Cooperation (Italy), Consejo Nacional de Ciencia y Tecnologia (CONACyT) 167733, Universidad Nacional Autonoma de Mexico (UNAM), PAPIIT DGAPA-UNAM, Netherlands-Ministry of Education, Culture and Science, Netherlands Organization for Scientific Research (NWO), Dutch national e-infrastructure, SURF Cooperative, Poland-Ministry of Science and Higher Education DIR/WK/2018/11, National Science Centre, Poland 2013/08/M/ST9/00322 2016/23/B/ST9/01635 HARMONIA 5-2013/10/M/ST9/00062 UMO-2016/22/M/ST9/00198, Portugal -Portuguese national funds, FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE), Romania-Romanian Ministry of Education and Research, the Program Nucleu within MCI PN19150201/16N/2019 PN19060102, Romania-Romanian Ministry of Educatio n and Research, the Program Nucleu within PNCDI III PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018, Slovenian Research Agency - Slovenia P1-0031 P1-0385 I00033 N1-0111, Spain-Ministerio de Economia, Industria y Competitividad FPA2017-85114-P FPA2017-85197-P, Xunta de Galicia European Commission ED431C 2017/07, Junta de Andalucia SOMM17/6104/UGR, European Commission, RENATA Red Nacional Tematica de Astroparticulas FPA2015-68783-REDT, Maria de Maeztu Unit of Excellence MDM-2016-0692, United States Department of Energy (DOE) DE-AC0207CH11359 DE-FR02-04ER41300 DE-FG0299ER41107 DE-SC0011689, National Science Foundation (NSF) 0450696, Grainger Foundation, Marie Curie-IRSES/EPLANET, European Particle Physics Latin American Network, UNESCO

Published
2021

23. Embedded readout electronics R&D for the large PMTs in the JUNO experiment

Author

Claudio Lombardo, S. Parmeggiano, Salvatore Costa, Jianrun Hu, Cristina Martellini, Nicomede Pelliccia, D. Corti, Andrea Fabbri, Xiongbo Yan, M. Mezzetto, Paolo Lombardi, Davide Chiesa, A. Garfagnini, Antonio Cammi, Roberto Isocrate, Jianmeng Dong, Anatael Cabrera, Alessandra Re, Jochen Steinmann, Z. Ning, Antonio Bergnoli, Andrea Serafini, Cecilia Landini, Augusto Brigatti, Monica Sisti, Zhang Chen, Jinnan Zhang, Fausto Ortica, S. van Waasen, Z. M. Wang, Giuseppe Verde, Giuseppe Salamanna, F. Li, Agnese Giaz, A. Brugnera, Antonio Budano, Michele Montuschi, Wenlu Wei, Song Chen, Yuman Wang, Richard Ford, M. Bellato, A. Stahl, Y. Yang, Marco Giammarchi, L. Stanco, E. Meroni, W. Bandini, Filippo Marini, P. Saggese, G. Galet, Ivano Lippi, Vitaly Shutov, Vito Antonelli, Alessandro Paoloni, D. Riondino, Barbara Clerbaux, Markus Robens, Cristina Tuve, S. Dusini, Andrey Formozov, Xuefeng Ding, G. Settanta, G. H. Gong, Fabio Mantovani, D. Pedretti, Giovanni Fiorentini, A. Barresi, Massimiliano Nastasi, Ezio Previtali, Barbara Ricci, Agnese Martini, Gioacchino Ranucci, Rossella Caruso, Yury Malyshkin, A. Aiello, A. Andronico, Pierre-Alexandre Petitjean, Chiara Sirignano, Virginia Strati, Xiaoshan Jiang, S. M. Mari, L. Votano, Lino Miramonti, Fatma Sawy, Alexander Olshevskiy, Y. J. Sun, Marco Fargetta, Aldo Romani, Riccardo Bruno, Christian Grewing, Paolo Montini, Marco Grassi, Catia Clementi, F. Dal Corso, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Bellato, M., Bergnoli, A., Brugnera, A., Chen, S., Chen, Z., Clerbaux, B., dal Corso, F., Corti, D., Dong, J., Galet, G., Garfagnini, A., Giaz, A., Gong, G., Grewing, C., Hu, J., Isocrate, R., Jiang, X., Li, F., Lippi, I., Marini, F., Ning, Z., Olshevskiy, A., Pedretti, D., Petitjean, P. A., Robens, M., Shutov, V., Stahl, A., Steinmann, J., Sun, Y., van Waasen, S., Wang, Y., Wang, Z., Wei, W., Yan, X., Yang, Y., Aiello, A., Andronico, A., Antonelli, V., Bandini, W., Brigatti, A., Barresi, A., Budano, A., Bruno, R., Cabrera, A., Cammi, A., Caruso, R., Chiesa, D., Clementi, C., Costa, S., Ding, X., Dusini, S., Fabbri, A., Fargetta, M., Fiorentini, G., Ford, R., Formozov, A., Giammarchi, M., Grassi, M., Landini, C., Lombardi, P., Lombardo, C., Malyshkin, Y., Mantovani, F., Mari, S. M., Martellini, C., Martini, A., Meroni, E., Mezzetto, M., Miramonti, L., Montini, P., Montuschi, M., Nastasi, M., Ortica, F., Paoloni, A., Parmeggiano, S., Pelliccia, N., Previtali, E., Ranucci, G., Riondino, D., Re, A. C., Ricci, B., Romani, A., Saggese, P., Salamanna, G., Sawy, F. H., Serafini, A., Settanta, G., Sirignano, C., Sisti, M., Stanco, L., Strati, V., Tuvé, C., Verde, G., Votano, L., and Zhang, J.

Subjects
Nuclear and High Energy Physics, Photomultiplier, Physics - Instrumentation and Detectors, Electronics, Large scale neutrino experiment, Physics::Instrumentation and Detectors, scintillation counter: liquid, 01 natural sciences, 7. Clean energy, NO, High Energy Physics - Experiment, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ddc:530, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Electronics, Photomultiplier, Large scale neutrino experiment, Instrumentation, Jiangmen Underground Neutrino Observatory, Physics, JUNO, 010308 nuclear & particles physics, Dynamic range, business.industry, Detector, Electrical engineering, Linearity, Analog signal, electronics: readout, Neutrino, business, performance, electronics: design
Abstract

Jiangmen Underground neutrino Observatory (JUNO) is a next generation liquid scintillator neutrino experiment under construction phase in South China. Thanks to the anti-neutrinos produced by the nearby nuclear power plants, JUNO will primarily study the neutrino mass hierarchy, one of the open key questions in neutrino physics. One key ingredient for the success of the measurement is to use high speed, high resolution sampling electronics located very close to the detector signal. Linearity in the response of the electronics in another important ingredient for the success of the experiment. During the initial design phase of the electronics, a custom design, with the Front-End and Read-Out electronics located very close to the detector analog signal has been developed and successfully tested. The present paper describes the electronics structure and the first tests performed on the prototypes. The electronics prototypes have been tested and they show good linearity response, with a maximum deviation of 1.3% over the full dynamic range (1-1000 p.e.), fulfilling the JUNO experiment requirements., Comment: 20 pages, 15 figures

Published
2021

24. FPGA Implementation of an NCO Based CDR for the JUNO Front-End Electronics

Author

Antonio Bergnoli, Monica Sisti, Antonio Budano, Michele Montuschi, D. Riondino, Andrey Formozov, A. Cammi, Ezio Previtali, Fabio Mantovani, Barbara Ricci, Agnese Giaz, Rossella Caruso, L. Stanco, S. Parmeggiano, Marco Danilo Claudio Torri, P. Saggese, S. Dusini, W. Bandini, Ivano Lippi, D. Corti, Andrea Fabbri, Cristina Tuve, Andrea Serafini, Cecilia Landini, Richard Ford, L. Votano, M. Mezzetto, Lino Miramonti, Massimiliano Nastasi, D. Basilico, Fausto Ortica, Marco Giammarchi, G. H. Gong, A. Brigatti, Chiara Sirignano, Alessandro Paoloni, M. Bellato, Paolo Lombardi, Xuefeng Ding, Salvatore Costa, Virginia Strati, Jianrun Hu, Xiaoshan Jiang, Andrea Barresi, Agnese Martini, G. Andronico, S. M. Mari, Roberto Isocrate, Sebastiano Aiello, Alessandra Re, Jianmeng Dong, Nicomede Pelliccia, R. Brugnera, Claudio Lombardo, B. Caccianiga, Marco Fargetta, Aldo Romani, Riccardo Bruno, Paolo Montini, Marco Grassi, Catia Clementi, Davide Chiesa, A. Garfagnini, Vito Antonelli, F. Dal Corso, Gioacchino Ranucci, Giuseppe Verde, Cristina Martellini, E. Meroni, Filippo Marini, K. von Sturm, Marini, F., Bellato, M., Bergnoli, A., Brugnera, R., Dal Corso, F., Corti, D., Dong, J., Garfagnini, A., Giaz, A., Gong, G., Hu, J., Isocrate, R., Jiang, X., Lippi, I., Von Sturm, K., Aiello, S., Andronico, G., Antonelli, V., Bandini, W., Basilico, D., Brigatti, A., Barresi, A., Budano, A., Bruno, R., Caccianiga, B., Cammi, A., Caruso, R., Chiesa, D., Clementi, C., Costa, S., Ding, X., Dusini, S., Fabbri, A., Fargetta, M., Ford, R., Formozov, A., Giammarchi, M., Grassi, M., Landini, C., Lombardi, P., Lombardo, C., Mantovani, F., Mari, S. M., Martellini, C., Martini, A., Meroni, E., Mezzetto, M., Miramonti, L., Montini, P., Montuschi, M., Nastasi, M., Ortica, F., Paoloni, A., Parmeggiano, S., Pelliccia, N., Previtali, E., Ranucci, G., Riondino, D., Re, A. C., Ricci, B., Romani, A., Saggese, P., Serafini, A., Sirignano, C., Sisti, M., Stanco, L., Strati, V., Torri, M., Tuve, C., Verde, G., Votano, L., Marini, F, Bellato, M, Bergnoli, A, Brugnera, R, Dal Corso, F, Corti, D, Dong, J, Garfagnini, A, Giaz, A, Gong, G, Hu, J, Isocrate, R, Jiang, X, Lippi, I, Von Sturm, K, Aiello, S, Andronico, G, Antonelli, V, Bandini, W, Basilico, D, Brigatti, A, Barresi, A, Budano, A, Bruno, R, Caccianiga, B, Cammi, A, Caruso, R, Chiesa, D, Clementi, C, Costa, S, Ding, X, Dusini, S, Fabbri, A, Fargetta, M, Ford, R, Formozov, A, Giammarchi, M, Grassi, M, Landini, C, Lombardi, P, Lombardo, C, Mantovani, F, Mari, S, Martellini, C, Martini, A, Meroni, E, Mezzetto, M, Miramonti, L, Montini, P, Montuschi, M, Nastasi, M, Ortica, F, Paoloni, A, Parmeggiano, S, Pelliccia, N, Previtali, E, Ranucci, G, Riondino, D, Re, A, Ricci, B, Romani, A, Saggese, P, Serafini, A, Sirignano, C, Sisti, M, Stanco, L, Strati, V, Torri, M, Tuve, C, Verde, G, and Votano, L

Subjects
Nuclear and High Energy Physics, phase aligner (PA), Clock signal, Computer science, Clock rate, CDR, Clock and data recovery (CDR), eye pattern, field-programmable gate array (FPGA), numerically-controlled oscillator (NCO), phase detector (PD), Phase detector, Digital clock, NO, PE2_2, Electrical and Electronic Engineering, Field-programmable gate array, Clock recovery, CDR ,NCO , phase detector, phase aligner , FPGA , eye pattern, FPGA, Jitter, phase aligner, business.industry, Detector, Nuclear Energy and Engineering, NCO, phase detector, business, Computer hardware
Abstract

This article describes a design of an field-programmable gate array (FPGA) implementation of a clock and data recovery (CDR) system. The core will be integrated in the FPGA configuration for the front-end electronics (FEE) board of the Jiangmen underground neutrino observatory (JUNO) experiment. The front-end will be placed on the main detector, underground and underwater, making the electronics not accessible after installation. The timing and trigger system relies on a synchronous link connection over CAT5e cable (up to 100 m long) between the front-end and the back-end electronics (BEE), where a twisted-pair is dedicated to clock-forwarding. The robustness of the recovery clock system is essential for the stability of the FPGA firmware. The proposed project is intended to improve the clock recovery operation by increasing the immunity of the link to sudden electromagnetic interference (EMI). On top of this, the core allows to free a twisted-pair in the link, since the clock can be recovered from the data and there is no more need for a clock-dedicated transmission. This will optimize the link granting the possibility to implement other features. The design is based on two components: a numerically-controlled oscillator (NCO), in order to create a controlled frequency clock signal, and a digital phase detector (PD) to match the clock frequency with the data rate. NCOs are often coupled with a digital-to-analog converter (DAC) to create direct digital synthesizers (DDSs), which are able to produce analog waveforms of any desired frequency. In the presented case instead, the NCO generates a digital clock signal of an arbitrary frequency, while the PD manages this frequency by intercepting any shifting on the relative phase between the clock and the data. A phase aligner (PA) module guarantees that data are sampled in the middle of the eye pattern, which represents the optimal sampling point. The article presents an overview of the NCO-based CDR design and implementation, together with some tests and results in order to verify the CDR reliability. Moreover, in the last section, some other possible applications of the core are illustrated.

Published
2021

25. Design, upgrade and characterization of the silicon photomultiplier front-end for the AMIGA detector at the Pierre Auger Observatory

Author

Silvia Mollerach, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, D. Zavrtanik, Serguei Vorobiov, J. Kleinfeller, Marcos Cerda, Denis Stanca, D. Melo, W. M. Namasaka, L. Lopes, A. C. Rovero, Alexandru Balaceanu, Carla Aramo, Julien Souchard, D. Martello, O. Martínez Bravo, K. Mulrey, Carla Bleve, Rodrigo Guedes Lang, Jaime Alvarez-Muñiz, Kevin-Druis Merenda, Alexandru Gherghel-Lascu, E. Santos, Thomas Bretz, Tiina Suomijarvi, V. Rizi, Corbin Covault, Vladimir Lenok, J. Stasielak, P. Tobiska, L. Perrone, L. Valore, R. Sato, Lino Miramonti, D. de Oliveira Franco, Lukáš Vaclavek, G. Mancarella, G. Marsella, A. Weindl, P. Savina, W. Rodrigues de Carvalho, Teresa Bister, Dalibor Nosek, M. Schimp, B. C. Manning, G. P. Guedes, Bjarni Pont, Luis A. Anchordoqui, A. Di Matteo, Marvin Gottowik, B. Keilhauer, P. Abreu, D. Ravignani, Alessio Gorgi, Maximilian Reininghaus, Flavia Gesualdi, Dusan Mandat, Sullivan Marafico, M. Risse, Orazio Zapparrata, Francesco Fenu, Ralf Ulrich, B. Wundheiler, Paul Sommers, Patricia María Hansen, Philipp Papenbreer, E. M. Santos, Eric Mayotte, Toshihiro Fujii, S. J. Sciutto, Juan Miguel Carceller, David Schmidt, J. Perez Armand, M. Gómez Berisso, S. Schröder, Italo Epicoco, Kai Daumiller, F. Sánchez, Marco Giammarchi, Nataliia Borodai, Christian Sarmiento-Cano, G. Parente, Fabrizia Canfora, K. Choi, L. Zehrer, Miroslav Pech, M. Pothast, Valerio Pirronello, C. J.W.P. Timmermans, C. M. Schäfer, C. J. Todero Peixoto, J. F. Valdés Galicia, I. De Mitri, Denise Boncioli, Jakub Juryšek, J. Debatin, Antonio Condorelli, Carola Dobrigkeit, M. Muzio, J. de Oliveira, Martin Vacula, Marcel Köpke, M. Platino, R. Alves Batista, Bruce R. Dawson, Trent D. Grubb, D. Nitz, Alejandro Almela, P. Horvath, J. Chudoba, P.O. Mazur, Darko Veberič, Julian Kemp, B. Andrada, A.L. Garcia Vegas, Sofia Andringa, M. A. Muller, A. Aab, G. Cataldi, Michael Prouza, Fred Sarazin, F. Riehn, T. Huege, Marina Scornavacche, A. Tapia, B. Tome, Josina Schulte, Alex Kääpä, Martina Bohacova, L. Nožka, G. De Mauro, F. Guarino, John Matthews, Peter Buchholz, Steffen Hahn, Claudio Galelli, Juan Carlos D'Olivo, T. Pierog, Juan Manuel Figueira, Mario Buscemi, L. R. Wiencke, Niklas Langner, Roberta Colalillo, Heino Falcke, V. Scherini, Maria Rita Coluccia, Jeffrey Brack, Olaf Scholten, Octavian Sima, Marco Aglietta, Marko Zavrtanik, H. Schieler, Esteban Roulet, A. G. Mariazzi, Justin M. Albury, Humberto Ibarguen Salazar, Hernán Asorey, M. I. Micheletti, Karl-Heinz Kampert, Antonella Castellina, Jonathan Biteau, J. Vicha, G. Farrar, Juan Pablo Gongora, K.-H. Becker, Nicolás González, Jose Chinellato, Alan Watson, H. Wilczyński, M. Suárez-Durán, Xavier Bertou, M. Perlin, Matias Tueros, Mihai Niculescu-Oglinzanu, M. Pimenta, I. Lhenry-Yvon, Jiri Blazek, E. De Vito, Giovanni Consolati, A. Zepeda, Gaetano Salina, Violet M. Harvey, D. Harari, Luis A. Nunez, Pedro Assis, P.R. Araújo Ferreira, Brian Fick, Piera Luisa Ghia, D. Lo Presti, S. J. De Jong, C. O. Escobar, A. Insolia, M. Kleifges, A.D. Supanitsky, H. Martinez, A. Etchegoyen, Marcus Niechciol, A. Taboada, J. Pȩkala, A. Fuster, Miguel Mostafa, Frank G. Schröder, Jarryd A. Day, A. Saftoiu, R.J. Barreira Luz, Tobias Winchen, Julien Manshanden, R. Conceição, A. Puyleart, Corinne Berat, M. Giller, Petr Schovanek, A.C. Cobos Cerutti, P.F. Gómez Vitale, Alina Mihaela Badescu, S. Querchfeld, Andres Travaini, E. Varela, J.D. Sanabria Gomez, Olena Tkachenko, V. Novotny, Ioana Caracas, Cristina Galea, J. R. T. de Mello Neto, L. Bonneau Arbeletche, A. Haungs, Rossella Caruso, A. Lucero, Fernando Catalani, J. Šupík, Carlo Ventura, Florian Lukas Briechle, Massimo Mastrodicasa, P. Ruehl, M. Schimassek, Caterina Trimarelli, Alena Bakalova, C. Hojvat, Jan Ebr, Ladislav Chytka, Samo Stanič, M. E. Bertaina, Markus Roth, M. HrabovskÃ, Jon Paul Lundquist, A. Menshikov, J. Hulsman, Juan Manuel González, P. Mantsch, B. L. Lago, P. Travnicek, Jacco Vink, H. Gemmeke, M. Unger, Jeffrey A. Johnsen, Z. Szadkowski, Gaia Silli, Isabel Goos, R. Squartini, A. Filipčič, D. Heck, Alfred Müller, H.O. Klages, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, S. Petrera, Marc Weber, A. Letessier-Selvon, Paula Gina Isar, M. del Río, Günter Sigl, Martín Miguel Freire, Roberto Mussa, P. Stassi, Radomir Smida, G. Medina-Tanco, A. A. Nucita, J. Rautenberg, A. Machado Payeras, B. García, R.C. Shellard, Q. Luce, F. Salamida, Maximilian Stadelmaier, R. López, Karen S. Caballero-Mora, R. M. de Almeida, A. Yushkov, Lorenzo Caccianiga, Lorenzo Cazon, G. Golup, Rodrigo Pelayo, Stijn Buitink, Martin Erdmann, François Montanet, J. de Jesús, A. Streich, Gioacchino Alex Anastasi, M. Wirtz, Eleonora Guido, Valerio Verzi, L. Nellen, Roger W Clay, Fernando Gollan, C. Morello, V. de Souza, Peter L. Biermann, Paolo Privitera, David Wittkowski, Olivier Deligny, Tomáš Fodran, Ugo Giaccari, Ioana Codrina Maris, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, G. C. Hill, I.D. Vergara Quispe, Jorge F. Soriano, Hernan Wahlberg, Ralph Engel, A. Parra, P. Ristori, M. Trini, I. Allekotte, M. J. Roncoroni, J. Pallotta, J. Ridky, A. M. Botti, Jörg R. Hörandel, H. J. Mathes, Stanislav Michal, J. Rodriguez Rojo, G. Matthiae, Fridtjof Feldbusch, Enrique Zas, Antonio Bueno, Fernando Contreras, Gualberto Avila, Dariusz Gora, John Farmer, Alan Coleman, Maria-Teresa Dova, M. R. Hampel, S. J. Saffi, F. Pedreira, Raul Sarmento, R.C. dos Anjos, Felix Schlüter, Adriana Vásquez-Ramírez, M. Palatka, Fabian Gobbi, Jesús Peña-Rodríguez, M.A. Leigui de Oliveira, High Energy Astrophys. & Astropart. Phys (API, FNWI), Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Muniz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Araujo Ferreira, P. R., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesus, J., de Jong, S. J., de Mauro, G., de Mello Neto, J. R. T., de Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Souza, V., de Vito, E., Debatin, J., del Rio, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Gomez Berisso, M., Gomez Vitale, P. F., Gongora, J. P., Gonzalez, J. M., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Lago, B. L., Lang, R. G., Langner, N., Leigui de Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Luce, Q., Lucero, A., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Martinez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nunez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pekala, J., Pelayo, R., Pena-Rodriguez, J., Perez Armand, J., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Ristori, P., Rizi, V., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Tapia, A., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tome, B., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Valdes Galicia, J. F., Valore, L., Varela, E., Varma, V. K. C., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Physics, Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Alves Batista R., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Araujo Ferreira P.R., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Bonneau Arbeletche L., Borodai N., Botti A.M., Brack J., Bretz T., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., de Almeida R.M., de Jesus J., de Jong S.J., de Mauro G., de Mello Neto J.R.T., de Mitri I., de Oliveira J., de Oliveira Franco D., de Souza V., de Vito E., Debatin J., del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Garcia Vegas A.L., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Lago B.L., Lang R.G., Langner N., Leigui de Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Luce Q., Lucero A., Lundquist J.P., Machado Payeras A., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pekala J., Pelayo R., Pena-Rodriguez J., Perez Armand J., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Ristori P., Rizi V., Rodrigues de Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Timmermans C., Tkachenko O., Tobiska P., Todero Peixoto C.J., Tome B., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Valdes Galicia J.F., Valore L., Varela E., Varma V.K.C., Vasquez-Ramirez A., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., and Research unit Astroparticle Physics

Subjects
Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, Astronomy, Performance of High Energy Physics Detector, 01 natural sciences, 7. Clean energy, Etc), 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Front-end electronics for detector readout, APDs, Instrumentation, physics.ins-det, Photon detectors for UV, Mathematical Physics, Instrumentation et méthodes en physique, EBCCDs, Visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc), electronics, Settore FIS/01 - Fisica Sperimentale, Calibration and fitting methods, Performance of High Energy Physics Detectors, Photon detectors for UV, visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc), Astrophysics::Instrumentation and Methods for Astrophysics, Si-PMTs, Instrumentation and Detectors (physics.ins-det), charged particle, CCDs, Cluster finding, CMOS imagers, EMCCDs, Pattern recognition, G-APDs, Visible and IR photons (solid-state) (PIN diodes, Auger, observatory, density [muon], Pattern recognition, cluster finding, calibration and fitting method, Christian ministry, upgrade, ddc:620, Astrophysics - Instrumentation and Methods for Astrophysics, performance, atmosphere [showers], Land access, Cherenkov counter: water, air, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], FOS: Physical sciences, 03 medical and health sciences, Political science, 0103 physical sciences, muon: density, photomultiplier: silicon, High Energy Physics, cosmic radiation: UHE, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], ddc:610, Instrumentation and Methods for Astrophysics (astro-ph.IM), Engineering & allied operations, scintillation counter, showers: atmosphere, 010308 nuclear & particles physics, water [Cherenkov counter], Autres mathématiques, Research council, efficiency, Experimental High Energy Physics, silicon [photomultiplier], High Energy Physics::Experiment, Humanities, RAIOS CÓSMICOS, astro-ph.IM
Abstract

The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargue. We are very grateful to the following agencies and organizations for financial support: Argentina -Comision Nacional de Energia Atomica; Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT); Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); Gobierno de la Provincia de Mendoza; Municipalidad de Malargue; NDM Holdings and Valle Las Lenas; in gratitude for their continuing cooperation over land access; Australia -the Australian Research Council; Brazil -Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq); Financiadora de Estudos e Projetos (FINEP); Fundacao de Amparo a Pesquisa do Estado de Rio de Janeiro (FAPERJ); Sao Paulo Research Foundation (FAPESP) Grants No. 2019/10151-2, No. 2010/07359-6 and No. 1999/05404-3; Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC); Czech Republic Grant No. MSMT CR LTT18004, LM2015038, LM2018102, CZ.02.1.01/0.0/0.0/16_013/0001402, CZ.02.1.01/0.0/0.0/18_046/0016010 and CZ.02.1.01/0.0/0.0/17_049/0008422; France -Centre de Calcul IN2P3/CNRS; Centre National de la Recherche Scientifique (CNRS); Conseil Regional Ile-de-France; Departement Physique Nucleaire et Corpusculaire (PNC-IN2P3/CNRS); Departement Sciences de l'Univers (SDU-INSU/CNRS); Institut Lagrange de Paris (ILP) Grant No. LABEX ANR-10-LABX-63 within the Investissements d'Avenir Programme Grant No. ANR-11-IDEX-0004-02; Germany-Bundesministerium fur Bildung und Forschung (BMBF); Deutsche Forschungsgemeinschaft (DFG); Finanzministerium Baden-Wurttemberg; Helmholtz Alliance for Astroparticle Physics (HAP); Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF); Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen; Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg; Italy-Istituto Nazionale di Fisica Nucleare (INFN); Istituto Nazionale di Astrofisica (INAF); Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR); CETEMPS Center of Excellence; Ministero degli Affari Esteri (MAE); Mexico-Consejo Nacional de Ciencia y Tecnologia (CONACYT) No. 167733; Universidad Nacional Autonoma de Mexico (UNAM); PAPIIT DGAPA-UNAM; The Netherlands -Ministry of Education, Culture and Science; Netherlands Organisation for Scientific Research (NWO); Dutch national e-infrastructure with the support of SURF Cooperative; Poland-Ministry of Science and Higher Education, grant No. DIR/WK/2018/11; National Science Centre, Grants No. 2013/08/M/ST9/00322, No. 2016/23/B/ST9/01635 and No. HARMONIA 5-2013/10/M/ST9/00062, UMO-2016/22/M/ST9/00198; Portugal -Portuguese national funds and FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE); Romania-Romanian Ministry of Education and Research, the Program Nucleu within MCI(PN19150201/16N/2019 and PN19060102) and project PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018 within PNCDI III; Slovenia -Slovenian Research Agency, grants P1-0031, P1-0385, I0-0033, N1-0111; Spain-Ministerio de Economia, Industria y Competitividad (FPA2017-85114-P and FPA2017-85197-P), Xunta de Galicia (ED431C 2017/07), Junta de Andalucia (SOMM17/6104/UGR), Feder Funds, RENATA Red Nacional Tematica de Astroparticulas (FPA2015-68783-REDT) and Maria de Maeztu Unit of Excellence (MDM-2016-0692); U.S.A. -Department of Energy, Contracts No. DE-AC02-07CH11359, No. DE-FR02-04ER41300, No. DE-FG02-99ER41107 and No. DE-SC0011689; National Science Foundation, Grant No. 0450696; The Grainger Foundation; Marie Curie-IRSES/EPLANET; European Particle Physics Latin American Network; and UNESCO., AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory to complement the study of ultra-high-energy cosmic rays (UHECR) by measuring the muon content of extensive air showers (EAS). It consists of an array of 61 water Cherenkov detectors on a denser spacing in combination with underground scintillation detectors used for muon density measurement. Each detector is composed of three scintillation modules, with 10 m(2) detection area per module, buried at 2.3 m depth, resulting in a total detection area of 30 m(2). Silicon photomultiplier sensors (SiPM) measure the amount of scintillation light generated by charged particles traversing the modules. In this paper, the design of the front-end electronics to process the signals of those SiPMs and test results from the laboratory and from the Pierre Auger Observatory are described. Compared to our previous prototype, the new electronics shows a higher performance, higher efficiency and lower power consumption, and it has a new acquisition system with increased dynamic range that allows measurements closer to the shower core. The new acquisition system is based on the measurement of the total charge signal that the muonic component of the cosmic ray shower generates in the detector., Argentina - Comision Nacional de Energia Atomica, Argentina - Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT), Argentina - Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Argentina - Gobierno de la Provincia de Mendoza, Argentina - Municipalidad de Malargue, Argentina - NDM Holdings, Argentina - Valle Las Lenas, Australian Research Council, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) Fundacao de Apoio a Pesquisa do Distrito Federal (FAPDF) Brazil - Financiadora de Estudos e Projetos (FINEP), Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio De Janeiro (FAPERJ), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) 2019/10151-2 2010/07359-6 1999/05404-3, Brazil - Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC), Brazil - Czech Republic Grant MSMT CR LTT18004 LM2015038 LM2018102 CZ.02.1.01/0.0/0.0/16_013/0001402 CZ.02.1.01/0.0/0.0/18_046/0016010 CZ.02.1.01/0.0/0.0/17_049/0008422, France - Centre de Calcul IN2P3/CNRS, Centre National de la Recherche Scientifique (CNRS), France - Conseil Regional Ile-de-France, France - Departement Physique Nucleaire et Corpusculaire (PNC-IN2P3/CNRS), France - Departement Sciences de l'Univers (SDU-INSU/CNRS), French National Research Agency (ANR) LABEX ANR-10-LABX-63, Institut Lagrange de Paris (ILP) within the Investissements d'Avenir Programme ANR-11-IDEX-0004-02, Federal Ministry of Education & Research (BMBF), Bundesministerium fur Bildung und Forschung (BMBF), German Research Foundation (DFG), Germany - Finanzministerium Baden-Wurttemberg, Germany - Helmholtz Alliance for Astroparticle Physics (HAP), Germany - Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF), Germany - Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Germany - Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg, Italy - Istituto Nazionale di Fisica Nucleare (INFN), Italy - Istituto Nazionale di Astrofisica (INAF), Italy - Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), Italy - CETEMPS Center of Excellence, Consejo Nacional de Ciencia y Tecnologia (CONACyT) 167733, Mexico - Universidad Nacional Autonoma de Mexico (UNAM), Mexico - PAPIIT DGAPA-UNAM, Netherlands - Ministry of Education, Culture and Science, Netherlands Organization for Scientific Research (NWO), Netherlands Organisation for Scientific Research (NWO), The Netherlands - SURF Cooperative, Poland - Ministry of Science and Higher Education DIR/WK/2018/11 Poland - National Science Centre 2013/08/M/ST9/00322 2016/23/B/ST9/01635 HARMONIA 5-2013/10/M/ST9/00062 UMO-2016/22/M/ST9/00198, Portugal - Portuguese national funds Portugal - FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE), Romania - Romanian Ministry of Education and Research Romania - Program Nucleu within MCI PN19150201/16N/2019 PN19060102 Romania - PNCDI III PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018, Slovenian Research Agency - Slovenia P1-0031 P1-0385 I0-0033 N1-0111, Spain - Ministerio de Economia, Industria y Competitividad FPA2017-85114-P FPA2017-85197-P, Spain - Xunta de Galicia ED431C 2017/07, Junta de Andalucia SOMM17/6104/UGR, Spain - Feder Funds, Spain - RENATA Red Nacional Tematica de Astroparticulas FPA2015-68783-REDT, Spain - Maria de Maeztu Unit of Excellence MDM-2016-0692, United States Department of Energy (DOE) DE-AC02-07CH11359, National Science Foundation (NSF) 0450696, U.S.A. - Grainger Foundation U.S.A. - Marie Curie-IRSES/EPLANET U.S.A. - European Particle Physics Latin American Network U.S.A. - UNESCO, Italy - Ministero degli Affari Esteri (MAE), The Netherlands - Dutch national e-infrastructure

Published
2021

26. Deep-learning based reconstruction of the shower maximum X max using the water-Cherenkov detectors of the Pierre Auger Observatory

Author

A. Segreto, Günter Sigl, Orazio Zapparrata, P. Stassi, Radomir Smida, A. Machado Payeras, G. Cataldi, V. Scherini, Carola Dobrigkeit, M. Muzio, Marcio Aparecido Muller, Srijan Sehgal, Fernando Gollan, Carla Bleve, Rodrigo Guedes Lang, M. E. Bertaina, F. de Palma, Alan Watson, M. Perlin, Mihai Niculescu-Oglinzanu, L. Valore, Belén Andrada, Marina Scornavacche, V. de Souza, G. Golup, Violet M. Harvey, D. Harari, N. Kunka, T. Bister, F. Riehn, P. Tobiska, Jonathan Biteau, M. I. Micheletti, A. Insolia, Jesús Peña-Rodríguez, Matías J. Roncoroni, Sullivan Marafico, M. Kleifges, D. Zavrtanik, Marco Giammarchi, R.J. Barreira Luz, D. Melo, G. P. Guedes, F. Salamida, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, A. Yushkov, Alina Mihaela Badescu, Ioana Codrina Maris, R. Sato, Lourenco Lopes, Toshihiro Fujii, S. Schröder, Italo Epicoco, Marvin Gottowik, Cristina Galea, M. Prouza, Brian Fick, Xavier Bertou, A. Di Matteo, Julian Kemp, Eric Mayotte, D. Nitz, Esteban Roulet, P. Abreu, D. Ravignani, R. M. de Almeida, K. H. Kampert, J. C. Arteaga Velázquez, J. Kleinfeller, A. Zepeda, M. Gómez Berisso, R. C. Shellard, Roberto Mussa, A. Puyleart, Jakub Juryšek, Petr Hamal, Steffen Hahn, Juan Carlos D'Olivo, Julien Manshanden, Lorenzo Caccianiga, Pedro Assis, H. Martinez, A. Etchegoyen, G. C. Hill, Corinne Berat, M. Giller, Jan Pękala, Rúben Conceição, Valerio Verzi, B. Tome, J. Chudoba, L. Lu, H. J. Mathes, Stanislav Michal, B. Wundheiler, Andres Travaini, K. Choi, Alex Kääpä, Ralph Engel, Flavia Gesualdi, J. Perez Armand, E. Varela, D. Correia dos Santos, J. Ridky, L. R. Wiencke, T. Pierog, François Montanet, Justin M. Albury, P. L. Ghia, Marcel Köpke, M. Platino, J.D. Sanabria Gomez, Rodrigo Pelayo, Jose J. Gonzalez, Stijn Buitink, Katie Mulrey, Carlos Escobar, G. De Mauro, Kevin-Druis Merenda, Vladimir Lenok, L. Perrone, H. Schieler, C. J. Todero Peixoto, Mario Buscemi, D. Nosek, E. Santos, Niklas Langner, Antonella Castellina, Eleonora Guido, Antonio Condorelli, M. Risse, Jörg R. Hörandel, J. F. Valdés Galicia, I. De Mitri, Jonathan Blazek, Jose Chinellato, J. Rodriguez Rojo, Fridtjof Feldbusch, A.L. Garcia Vegas, Enrique Zas, I. Lhenry-Yvon, C. Trimarelli, Gaia Silli, A. Filipčič, A.D. Supanitsky, Philipp Papenbreer, Claudio Galelli, A. Weindl, M. Suárez-Durán, J. Stasielak, T. Huege, Hernán Gonzalo Asorey, L. Nellen, L. Anchordoqui, Alena Bakalova, C. Morello, Miroslav Hrabovský, Petr Travnicek, Trent D. Grubb, G. Parente, Fabrizia Canfora, Fernando Contreras, A. Haungs, Juan Manuel Figueira, Roberta Colalillo, Paul Sommers, Clara Keiko Oliveira Watanabe, B. García, M. Schimp, A. G. Mariazzi, R. López, Karen S. Caballero-Mora, H. Wilczyński, Ioana Caracas, A. Letessier-Selvon, Lorenzo Cazon, C. Pérez Bertolli, F. Sanchez, F. Sarazin, S. Petrera, Marc Weber, David Schmidt, G. Farrar, L. Zehrer, J. de Oliveira, Alejandro Almela, P. Mantsch, Z. Szadkowski, M. Schimassek, C. Hojvat, Jan Ebr, Jacco Vink, Peter L. Biermann, L. Bonneau Arbeletche, Maximilian Reininghaus, Paolo Privitera, M. A. Leigui de Oliveira, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, Martin Erdmann, J. de Jesús, A. Taboada, G. Marsella, E. M. Santos, A. Gorgi, H.O. Klages, B. C. Manning, Dariusz Gora, Bjarni Pont, Thomas Bretz, Petr Janecek, Corbin Covault, Matías Rolf Hampel, Frank G. Schröder, R. Squartini, Alfred Müller, P.F. Gómez Vitale, A. Streich, Gioacchino Alex Anastasi, M. Wirtz, David Wittkowski, G. Salina, Roger W Clay, Olivier Deligny, W. M. Namasaka, M. Mastrodicasa, A. C. Rovero, Alexandru Balaceanu, A. A. Nucita, Alan Coleman, Lino Miramonti, S. J. Saffi, Lukáš Vaclavek, J. F. Soriano, D. de Oliveira Franco, R. Alves Batista, Bruce R. Dawson, Octavian Sima, Ana Martina Botti, Jeffrey Brack, Olaf Scholten, P.O. Mazur, K.-H. Becker, Maria Rita Coluccia, Dusan Mandat, Francesco Fenu, Humberto Ibarguen Salazar, M. Pimenta, Tomáš Fodran, Alina Nasr-Esfahani, P.R. Araújo Ferreira, Tobias Winchen, G. Mancarella, B. Keilhauer, Florian Lukas Briechle, Darko Veberič, Ugo Giaccari, S. J. Sciutto, F. Pedreira, Christian Sarmiento-Cano, Raul Sarmento, G. Medina-Tanco, Felix Schlüter, P. Ruehl, Carla Aramo, Vincenzo Rizi, C. J.W.P. Timmermans, Julien Souchard, Jon Paul Lundquist, A. Menshikov, D. Martello, Juan Miguel Carceller, C. M. Schäfer, Markus Roth, Silvia Mollerach, O. Martínez Bravo, Isabel Goos, D. Heck, A. Tapia, Josina Schulte, Peter Hansen, M. del Río, H. Gemmeke, Fabian Gobbi, B. L. Lago, P. Savina, W. Rodrigues de Carvalho, Denise Boncioli, M. Unger, F. Guarino, John Matthews, Peter Buchholz, Marco Aglietta, Miguel Mostafa, E.E. Pereira Martins, Serguei Vorobiov, Martina Bohacova, Miroslav Pech, M. Pothast, J. Hulsman, J. Rautenberg, Pavel Horvath, Q. Luce, Marcus Niechciol, Juan Pablo Gongora, Paula Gina Isar, Sofia Andringa, Maximilian Stadelmaier, Nataliia Borodai, Marcos Cerda, D. Lo Presti, S. J. De Jong, Samo Stanič, Jarryd A. Day, A. Saftoiu, A.C. Cobos Cerutti, Martin Vacula, J. R. T. de Mello Neto, V. Novotny, V. K.C. Varma, Rossella Caruso, A. Lucero, Fernando Catalani, N. González, Kai Daumiller, Heino Falcke, S. Querchfeld, Olena Tkachenko, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, J. Šupík, Carlo Ventura, Martín Miguel Freire, V. Pirronello, J. Vicha, Ladislav Chytka, A. Aab, Carla Taricco, Matias Tueros, Luis A. Nunez, T. Suomijärvi, J. Pallotta, Hernan Wahlberg, A. Parra, A. Fuster, M. Trini, P.G. Brichetto Orchera, I. Allekotte, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, I.D. Vergara Quispe, M. Zavrtanik, E. De Vito, Giovanni Consolati, Petr Schovanek, Denis Stanca, Ralf Ulrich, L. Nožka, G. Matthiae, Antonio Bueno, Gualberto Avila, John Farmer, Maria-Teresa Dova, R.C. dos Anjos, Adriana Vásquez-Ramírez, M. Palatka, Jeffrey A. Johnsen, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Mu??iz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ara??jo Ferreira, P. R., Arteaga Vel??zquez, J. C., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Boh????ov??, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Brichetto Orchera, P. G., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Concei????o, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Correia dos Santos, D., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jes??s, J., de Jong, S. J., De Mauro, G., de Mello Neto, J. R. T., De Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Palma, F., de Souza, V., De Vito, E., del R??o, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filip??i??, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garc??a, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., G??mez Berisso, M., G??mez Vitale, P. F., Gongora, J. P., Gonz??lez, J. M., Gonz??lez, N., Goos, I., G??ra, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., H??randel, J. R., Horvath, P., Hrabovsk??, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., K????p??, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., K??pke, M., Kunka, N., Lago, B. L., Lang, R. G., Langner, N., Leigui de Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., L??pez, R., Lu, L., Luce, Q., Lucero, A., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Mari??, I. C., Marsella, G., Martello, D., Martinez, H., Mart??nez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostaf??, M., M??ller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., No??ka, L., Nucita, A., N????ez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., P??kala, J., Pelayo, R., Pe??a-Rodriguez, J., Pereira Martins, E. E., Perez Armand, J., P??rez Bertolli, C., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., S??nchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Sch??fer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schl??ter, F., Schmidt, D., Scholten, O., Schov??nek, P., Schr??der, F. G., Schr??der, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shellard, R. C., Sigl, G., Silli, G., Sima, O., m??da, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stani??, S., Stasielak, J., Stassi, P., Streich, A., Su??rez-Dur??n, M., Sudholz, T., Suomij??rvi, T., Supanitsky, A. D., up??k, J., Szadkowski, Z., Taboada, A., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tom??, B., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Galicia, J. F. Vald??s., Valore, L., Varela, E., Varma K. C., V., V??squez-Ram??rez, A., Veberi??, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watanabe, C., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczy??ski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., High Energy Astrophys. & Astropart. Phys (API, FNWI), Gravitation and Astroparticle Physics Amsterdam, Astronomy and Astrophysics Research Group, Physics, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Batista R.A., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Ferreira P.R.A., Velazquez J.C.A., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Luz R.J.B., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Arbeletche L.B., Borodai N., Botti A.M., Brack J., Bretz T., Orchera P.G.B., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cerutti A.C.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., dos Santos D.C., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., de Almeida R.M., de Jesus J., de Jong S.J., de Mauro G., de Mello Neto J.R.T., de Mitri I., de Oliveira J., de Oliveira Franco D., de Palma F., de Souza V., de Vito E., del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Vegas A.L.G., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Berisso M.G., Vitale P.F.G., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hamal P., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Janecek P., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kunka N., Lago B.L., Lang R.G., Langner N., de Oliveira M.A.L., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Presti D.L., Lopes L., Lopez R., Lu L., Luce Q., Lucero A., Lundquist J.P., Payeras A.M., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Bravo O.M., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nasr-Esfahani A., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pekala J., Pelayo R., Pena-Rodriguez J., Martins E.E.P., Armand J.P., Bertolli C.P., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Rizi V., Rodrigues de Carvalho W., Rojo J.R., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Gomez J.D.S., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Segreto A., Sehgal S., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Taricco C., Timmermans C., Tkachenko O., Tobiska P., Peixoto C.J.T., Tome B., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Galicia J.F.V., Valore L., Varela E., Varma V.K.C., Vasquez-Ramirez A., Veberic D., Ventura C., Quispe I.D.V., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watanabe C., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., Research unit Astroparticle Physics, Alvarez-Muniz, J., Batista, R. A., Ferreira, P. R. A., Velazquez, J. C. A., Luz, R. J. B., Bohacova, M., Arbeletche, L. B., Orchera, P. G. B., Cerutti, A. C. C., Conceicao, R., dos Santos, D. C., de Jesus, J., de Mauro, G., de Mitri, I., de Vito, E., del Rio, M., Filipcic, A., Garcia, B., Vegas, A. L. G., Berisso, M. G., Vitale, P. F. G., Gonzalez, J. M., Gonzalez, N., Gora, D., Horandel, J. R., Hrabovsky, M., Kaapa, A., Kopke, M., de Oliveira, M. A. L., Presti, D. L., Lopez, R., Payeras, A. M., Maris, I. C., Bravo, O. M., Mostafa, M., Muller, A. L., Nozka, L., Nunez, L. A., Pekala, J., Pena-Rodriguez, J., Martins, E. E. P., Armand, J. P., Bertolli, C. P., Rojo, J. R., Gomez, J. D. S., Sanchez, F., Schafer, C. M., Schluter, F., Schovanek, P., Schroder, F. G., Schroder, S., Smida, R., Stanic, S., Suarez-Duran, M., Suomijarvi, T., Supik, J., Peixoto, C. J. T., Tome, B., Galicia, J. F. V., Varma, V. K. C., Vasquez-Ramirez, A., Veberic, D., Quispe, I. D. V., and Wilczynski, H.

Subjects
showers: energy, longitudinal [showers], interaction: model, Physics::Instrumentation and Detectors, Astronomy, Calibration and fitting methods, Cluster finding, Data analysis, Large detector systems for particle and astroparticle physics, Particle identification methods, Pattern recognition, 01 natural sciences, High Energy Physics - Experiment, Auger, High Energy Physics - Experiment (hep-ex), cluster finding, surface [detector], Observatory, Large detector systems, Instrumentation, Mathematical Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Physics, Pattern recognition, cluster finding, calibration and fitting methods, Settore FIS/01 - Fisica Sperimentale, model [interaction], Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Data analysi, calibration and fitting methods, energy [showers], observatory, Pattern recognition, cluster finding, calibration and fitting method, astroparticle physics, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, atmosphere [showers], air, neural network, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], FOS: Physical sciences, Cosmic ray, detector: fluorescence, 0103 physical sciences, ddc:530, High Energy Physics, ddc:610, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], cosmic radiation: UHE, structure, particle physics, network: performance, 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Ciencias Exactas, Cherenkov radiation, fluorescence [detector], Pierre Auger Observatory, mass spectrum [nucleus], showers: atmosphere, detector: surface, hep-ex, 010308 nuclear & particles physics, Física, resolution, calibration, Computational physics, performance [network], Cherenkov counter, Air shower, Large detector systems for particle and astroparticle physic, Experimental High Energy Physics, High Energy Physics::Experiment, nucleus: mass spectrum, showers: longitudinal, RAIOS CÓSMICOS, Energy (signal processing), astro-ph.IM
Abstract

The atmospheric depth of the air shower maximum $X_{\mathrm{max}}$ is an observable commonly used for the determination of the nuclear mass composition of ultra-high energy cosmic rays. Direct measurements of $X_{\mathrm{max}}$ are performed using observations of the longitudinal shower development with fluorescence telescopes. At the same time, several methods have been proposed for an indirect estimation of $X_{\mathrm{max}}$ from the characteristics of the shower particles registered with surface detector arrays. In this paper, we present a deep neural network (DNN) for the estimation of $X_{\mathrm{max}}$. The reconstruction relies on the signals induced by shower particles in the ground based water-Cherenkov detectors of the Pierre Auger Observatory. The network architecture features recurrent long short-term memory layers to process the temporal structure of signals and hexagonal convolutions to exploit the symmetry of the surface detector array. We evaluate the performance of the network using air showers simulated with three different hadronic interaction models. Thereafter, we account for long-term detector effects and calibrate the reconstructed $X_{\mathrm{max}}$ using fluorescence measurements. Finally, we show that the event-by-event resolution in the reconstruction of the shower maximum improves with increasing shower energy and reaches less than $25~\mathrm{g/cm^{2}}$ at energies above $2\times 10^{19}~\mathrm{eV}$., Published version, 29 pages, 12 figures

Published
2021

27. Comparison between drug therapy-based comorbidity indices and the Charlson Comorbidity Index for the detection of severe multimorbidity in older subjects

Author

Alessio, Novella, Chiara, Elli, Mauro, Tettamanti, Alessandro, Nobili, Aladar, Ianes, Pier Mannuccio Mannucci, Luca, Pasina, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Matteo, Cesari, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracian, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Alessandra, Marengoni, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio, Brucato, Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, DE GIORGI, Alfredo, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Fracanzani, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Francesco, Salerno, Giada, Pallini, Fabrizio, Montecucco, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Francesco, Violi, Ludovica, Perri, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Roberta, Gonella, Domenico, Cerminara, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Silvia, Ghidoni, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, Federica, Gandolfo., Novella, A, Elli, C, Tettamanti, M, Nobili, A, Ianes, A, Mannucci, P, Pasina, L, and Bellelli, G

Subjects
Aging, medicine.medical_specialty, Comorbidity indices, Socio-culturale, Comorbidity, Logistic regression, 03 medical and health sciences, 0302 clinical medicine, Pharmacotherapy, Internal medicine, Medicine, Humans, LS4_4, 030212 general & internal medicine, Medical prescription, Medical diagnosis, Older adult, Operating characteristic, Disease burden, Aged, Receiver operating characteristic, business.industry, Chronic diseae, Area under the curve, Multimorbidity, medicine.disease, Comorbidity indice, Hospitalization, Italy, Multimorbidiy, Older adults, Chronic Disease, Chronic disease, Comorbidity indices, Multimorbidiy, Older adults, Operating characteristic, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery
Abstract

Background: To know burden disease of a patient is a key point for clinical practice and research, especially in the elderly. Charlson’s Comorbidity Index (CCI) is the most widely used rating system, but when diagnoses are not available therapy-based comorbidity indices (TBCI) are an alternative. However, their performance is debated. This study compares the relations between Drug Derived Complexity Index (DDCI), Medicines Comorbidity Index (MCI), Chronic Disease Score (CDS), and severe multimorbidity, according to the CCI classification, in the elderly. Methods: Logistic regression and Receiver Operating Characteristic (ROC) analysis were conducted on two samples from Italy: 2579 nursing home residents (Korian sample) and 7505 older adults admitted acutely to geriatric or internal medicine wards (REPOSI sample). Results: The proportion of subjects with severe comorbidity rose with TBCI score increment, but the Area Under the Curve (AUC) for the CDS (Korian: 0.70, REPOSI: 0.79) and MCI (Korian: 0.69, REPOSI: 0.81) were definitely better than the DDCI (Korian: 0.66, REPOSI: 0.74). All TBCIs showed low Positive Predictive Values (maximum: 0.066 in REPOSI and 0.317 in Korian) for the detection of severe multimorbidity. Conclusion: CDS and MCI were better predictors of severe multimorbidity in older adults than DDCI, according to the CCI classification. A high CCI score was related to a high TBCI. However, the opposite is not necessarily true probably because of non-evidence-based prescriptions or physicians’ prescribing attitudes. TBCIs did not appear selective for detecting of severe multimorbidity, though they could be used as a measure of disease burden, in the absence of other solutions.

Published
2021

28. The energy spectrum of cosmic rays beyond the turn-down around 1017 eV as measured with the surface detector of the Pierre Auger Observatory

Author

A. C. Fauth, Vladimir Lenok, L. Perrone, M. I. Micheletti, M. Risse, Jonathan Blazek, Alessio Gorgi, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, Marvin Gottowik, G. Matthiae, Brian Fick, Orazio Zapparrata, Antonio Bueno, Carola Dobrigkeit, M. Muzio, G. Parente, D. Melo, J. Rautenberg, M. E. Bertaina, Abha Khakurdikar, P. Abreu, Fabrizia Canfora, D. Ravignani, L. Bonneau Arbeletche, L. Zehrer, Q. Luce, M. Schimassek, C. Hojvat, Jan Ebr, Alan Watson, I.D. Vergara Quispe, G. P. Guedes, Toshihiro Fujii, Jakub Juryšek, Petr Hamal, Steffen Hahn, Juan Carlos D'Olivo, T. Pierog, Eric Mayotte, Esteban Roulet, M. Gómez Berisso, R. C. Shellard, Justin M. Albury, P. L. Ghia, Gualberto Avila, Sara Martinelli, M. Perlin, Mihai Niculescu-Oglinzanu, Zoé Torrès, Dariusz Gora, B. Tome, Josina Schulte, Maximilian Stadelmaier, F. Riehn, Marina Scornavacche, Jonathan Biteau, K. H. Kampert, J. C. Arteaga Velázquez, Ioana Codrina Maris, Octavian Sima, J. de Oliveira, R. Conceição, Alejandro Almela, Jacco Vink, H.O. Klages, Alan Coleman, Peter Hansen, F. Guarino, John Matthews, Peter Buchholz, J. F. Valdés Galicia, L. Valore, D. Nitz, W. M. Namasaka, A. C. Rovero, S. J. Saffi, Isabel Goos, D. Heck, Jeffrey A. Johnsen, Miroslav Hrabovský, A. Haungs, Julien Manshanden, V. V. Kizakke Covilakam, Andres Travaini, A. Segreto, Günter Sigl, D. Nosek, E. Santos, A. A. Nucita, I. De Mitri, R. Sato, M. del Río, P. Stassi, Hernan Wahlberg, Radomir Smida, Mario Buscemi, John Farmer, F. Fenu, A. Machado Payeras, Violet M. Harvey, D. Harari, Marcel Köpke, M. Platino, G. C. Hill, P. Mantsch, D. Lo Presti, S. J. De Jong, Alexandru Balaceanu, Z. Szadkowski, E. Varela, J.D. Sanabria Gomez, Roberto Mussa, Marco Aglietta, Julian Kemp, Paul Sommers, Srijan Sehgal, Jorge F. Soriano, Thomas Hebbeker, Fernando Gollan, Max Büsken, Sergio Dasso, Tristan Sudholz, Martín Miguel Freire, M. A. Leigui de Oliveira, F. Pedreira, V. de Souza, Carla Aramo, Vincenzo Rizi, J. Perez Armand, Maria-Teresa Dova, M. R. Hampel, Pierre Billoir, A. Puyleart, Corinne Berat, Julien Souchard, Thomas Fitoussi, D. Martello, Alena Bakalova, Jarryd A. Day, A. Saftoiu, Ralph Engel, J. Ridky, A. Parra, M. Zavrtanik, L. R. Wiencke, Niklas Langner, Alex Kääpä, Marcio Aparecido Muller, Martina Bohacova, Giovanni Mancarella, O. Martínez Bravo, K. Mulrey, F. Sánchez, Miroslav Pech, V. Pirronello, Raul Sarmento, Felix Schlüter, Fabian Gobbi, Sullivan Marafico, Juan Pablo Gongora, Alina Mihaela Badescu, A. Weindl, Cristina Galea, François Montanet, M. Pothast, A.C. Cobos Cerutti, F. de Palma, E. De Vito, Darko Veberič, M. Suárez-Durán, Pavel Horvath, Claudio Galelli, M. Prouza, P. Ruehl, Marco Giammarchi, Clara Keiko Oliveira Watanabe, Flavia Gesualdi, J. R. T. de Mello Neto, Carla Taricco, Carla Bleve, Rodrigo Guedes Lang, R. M. de Almeida, T. Huege, Jeffrey Brack, Matias Tueros, G. Golup, Humberto Ibarguen Salazar, Eleonora Guido, Giovanni Consolati, Frank G. Schröder, N. Kunka, Maria Rita Coluccia, Maximilian Reininghaus, P. Tobiska, B. Andrada, K.-H. Becker, M. Pimenta, Silvia Mollerach, T. Bister, G. Marsella, H. Schieler, Jesús Peña-Rodríguez, P.G. Brichetto Orchera, David Wittkowski, G. Salina, Olivier Deligny, D. Correia dos Santos, Rodrigo Pelayo, Antonella Castellina, Stijn Buitink, V. Novotny, Luis A. Nunez, J. Stasielak, Jannis Pawlowsky, Rossella Caruso, Fernando Catalani, D. D. dos Santos, Sofia Andringa, R.C. dos Anjos, N. Fazzini, David Schmidt, Adriana Vásquez-Ramírez, Jonas Glombitza, F. C. T. Barbato, I. Allekotte, M. J. Roncoroni, Caterina Trimarelli, P.R. Araújo Ferreira, S. Schröder, Italo Epicoco, A. L. Müller, Tomáš Fodran, Alina Nasr-Esfahani, Thomas Bretz, Miguel Mostafa, Daniela Mockler, Petr Schovanek, L. Lopes, A. Di Matteo, R. Squartini, Florian Lukas Briechle, Petr Janecek, Corbin Covault, T. Suomijärvi, J. Pallotta, Juan Manuel González, G. De Mauro, M. Palatka, Gaia Silli, A. Tapia, A. Filipčič, Jörg R. Hörandel, L. Lu, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, J. Chudoba, M. Schimp, G. Cataldi, Ugo Giaccari, B. Wundheiler, Martin Vacula, Christian Sarmiento-Cano, W. Rodrigues de Carvalho, Virginia Binet, Luis A. Anchordoqui, Massimo Mastrodicasa, F. Sarazin, Lino Miramonti, B. C. Manning, H. Gemmeke, Jon Paul Lundquist, Markus Roth, A. M. Botti, M. Unger, S. Petrera, H. J. Mathes, Marc Weber, Stanislav Michal, Dusan Mandat, V. Scherini, Philipp Papenbreer, Jose Chinellato, Heino Falcke, D. de Oliveira Franco, Samo Stanič, A. Menshikov, Denis Stanca, Lukáš Vaclavek, R.J. Barreira Luz, Petr Travnicek, A. Fuster, I. Lhenry-Yvon, Denise Boncioli, L. Nellen, B. García, Bjarni Pont, B. Keilhauer, C. M. Schäfer, J. Kleinfeller, Ioana Caracas, J. Rodriguez Rojo, J. Vicha, Trent D. Grubb, A. Letessier-Selvon, Serguei Vorobiov, R. López, Karen S. Caballero-Mora, Lorenzo Cazon, C. Pérez Bertolli, N. González, P. Savina, G. Medina-Tanco, Nataliia Borodai, Marcus Niechciol, Fridtjof Feldbusch, Enrique Zas, André Schulz, Juan Manuel Figueira, Roberta Colalillo, S. J. Sciutto, C. J.W.P. Timmermans, C. Morello, L. M. Domingues Mendes, Carlos Escobar, A. G. Mariazzi, Kevin-Druis Merenda, Kai Daumiller, Ralf Ulrich, Martin Erdmann, Fernando Contreras, Juan Miguel Carceller, Xavier Bertou, G. Farrar, Nikolaos Karastathis, Antonio Condorelli, Peter L. Biermann, S. Querchfeld, Olena Tkachenko, Marcos Cerda, Pedro Assis, H. Martinez, J. de Jesús, A. Streich, Gioacchino Alex Anastasi, C. J. Todero Peixoto, A. Insolia, A. Etchegoyen, M. Kleifges, D. Zavrtanik, A.D. Supanitsky, J. Pȩkala, A.L. Garcia Vegas, M. Wirtz, Roger W Clay, Paolo Privitera, Carlo Ventura, F. Salamida, A. Yushkov, Ladislav Chytka, L. Nožka, Lorenzo Caccianiga, P.F. Gómez Vitale, Hernán Asorey, H. Wilczyński, E. M. Santos, Valerio Verzi, Kathrin Bismark, O. Scholten, R. Alves Batista, Bruce R. Dawson, P.O. Mazur, B. L. Lago, E.E. Pereira Martins, Paula Gina Isar, High Energy Astrophys. & Astropart. Phys (API, FNWI), Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Muniz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Araujo Ferreira, P. R., Arteaga Velazquez, J. C., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Billoir, P., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Brichetto Orchera, P. G., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Busken, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Correia dos Santos, D., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesus, J., de Jong, S. J., De Mauro, G., de Mello Neto, J. R. T., De Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Palma, F., de Souza, V., De Vito, E., del Rio, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., Domingues Mendes, L. M., dos Anjos, R. C., dos Santos, D., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fitoussi, T., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Gomez Berisso, M., Gomez Vitale, P. F., Gongora, J. P., Gonzalez, J. M., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Karastathis, N., Keilhauer, B., Kemp, J., Khakurdikar, A., Kizakke Covilakam, V. V., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Kunka, N., Lago, B. L., Lang, R. G., Langner, N., Leigui de Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Lu, L., Luce, Q., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinelli, S., Martinez, H., Martinez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mockler, D., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nunez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pawlowsky, J., Pech, M., Pedreira, F., Pekala, J., Pelayo, R., Pena-Rodriguez, J., Pereira Martins, E. E., Perez Armand, J., Perez Bertolli, C., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulte, J., Schulz, A., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Szadkowski, Z., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tome, B., Torres, Z., Travaini, A., Travnicek, P., Trimarelli, C., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Valdes Galicia, J. F., Valore, L., Varela, E., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watanabe, C., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Physics, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Alves Batista R., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Araujo Ferreira P.R., Arteaga Velazquez J.C., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Billoir P., Binet V., Bismark K., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Bonneau Arbeletche L., Borodai N., Botti A.M., Brack J., Bretz T., Brichetto Orchera P.G., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Busken M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Correia dos Santos D., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., de Almeida R.M., de Jesus J., de Jong S.J., De Mauro G., de Mello Neto J.R.T., De Mitri I., de Oliveira J., de Oliveira Franco D., de Palma F., de Souza V., De Vito E., del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., Domingues Mendes L.M., dos Anjos R.C., dos Santos D., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fitoussi T., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Garcia Vegas A.L., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Glombitza J., Gobbi F., Gollan F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hamal P., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Insolia A., Isar P.G., Janecek P., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Karastathis N., Keilhauer B., Kemp J., Khakurdikar A., Kizakke Covilakam V.V., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kunka N., Lago B.L., Lang R.G., Langner N., Leigui de Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Lu L., Luce Q., Lundquist J.P., Machado Payeras A., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinelli S., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mockler D., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nasr-Esfahani A., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pawlowsky J., Pech M., Pedreira F., Pekala J., Pelayo R., Pena-Rodriguez J., Pereira Martins E.E., Perez Armand J., Perez Bertolli C., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Rizi V., Rodrigues de Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Schulz A., Sciutto S.J., Scornavacche M., Segreto A., Sehgal S., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Szadkowski Z., Tapia A., Taricco C., Timmermans C., Tkachenko O., Tobiska P., Todero Peixoto C.J., Tome B., Torres Z., Travaini A., Travnicek P., Trimarelli C., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Valdes Galicia J.F., Valore L., Varela E., Vasquez-Ramirez A., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watanabe C., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., and Zehrer L.

Subjects
Physics and Astronomy (miscellaneous), Astronomy, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], FOS: Physical sciences, Flux, Cosmic ray, Astrophysics, 7. Clean energy, 01 natural sciences, detector: fluorescence, Auger, cosmic rays, surface [detector], Observatory, 0103 physical sciences, calorimeter, ddc:530, High Energy Physics, cosmic radiation: UHE, spectrum [cosmic radiation], 010303 astronomy & astrophysics, Engineering (miscellaneous), Engineering & allied operations, High Energy Astrophysical Phenomena (astro-ph.HE), fluorescence [detector], Pierre Auger Observatory, Physics, astro-ph.HE, cosmic radiation: energy spectrum, cosmic radiation: spectrum, detector: surface, 010308 nuclear & particles physics, Settore FIS/01 - Fisica Sperimentale, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Calorimeter, flux, observatory, spectral, ddc:620, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics - High Energy Astrophysical Phenomena, energy spectrum [cosmic radiation], Energy (signal processing), RAIOS CÓSMICOS, ultra-high energy cosmic rays, energy spectrum features
Abstract

The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargüe. We are very grateful to the following agencies and organizations for financial support: Argentina – Comisión Nacional de Energía Atómica; Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Gobierno de la Provincia de Mendoza; Municipalidad de Malargüe; NDM Holdings and Valle Las Leñas; in gratitude for their continuing cooperation over land access; Australia – the Australian Research Council; Belgium – Fonds de la Recherche Scientifique (FNRS); Research Foundation Flanders (FWO); Brazil – Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Financiadora de Estudos e Projetos (FINEP); Fundação de Amparo à Pesquisa do Estado de Rio de Janeiro (FAPERJ); São Paulo Research Foundation (FAPESP) Grants No. 2019/10151-2, No. 2010/07359-6 and No. 1999/05404-3; Ministério da Ciência, Tecnologia, Inovações e Comunicações (MCTIC); Czech Republic – Grant No. MSMT CR LTT18004, LM2015038, LM2018102, CZ.02.1.01/0.0/0.0/16_013/0001402, CZ.02.1.01/0.0/0.0/18_046/0016010 and CZ.02.1.01/0.0/0.0/17_049/0008422; France – Centre de Calcul IN2P3/CNRS; Centre National de la Recherche Scientifique (CNRS); Conseil Régional Ile-de-France; Département Physique Nucléaire et Corpusculaire (PNC-IN2P3/CNRS); Département Sciences de l’Univers (SDU-INSU/CNRS); Institut Lagrange de Paris (ILP) Grant No. LABEX ANR-10-LABX-63 within the Investissements d’Avenir Programme Grant No. ANR-11-IDEX-0004-02; Germany – Bundesministerium für Bildung und Forschung (BMBF); Deutsche Forschungsgemeinschaft (DFG); Finanzministerium Baden-Württemberg; Helmholtz Alliance for Astroparticle Physics (HAP); Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF); Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen; Ministerium für Wissenschaft, Forschung und Kunst des Landes Baden-Württemberg; Italy – Istituto Nazionale di Fisica Nucleare (INFN); Istituto Nazionale di Astrofisica (INAF); Ministero dell’Istruzione, dell’Universitá e della Ricerca (MIUR); CETEMPS Center of Excellence; Ministero degli Affari Esteri (MAE); México – Consejo Nacional de Ciencia y Tecnología (CONACYT) No. 167733; Universidad Nacional Autónoma de México (UNAM); PAPIIT DGAPA-UNAM; The Netherlands – Ministry of Education, Culture and Science; Netherlands Organisation for Scientific Research (NWO); Dutch national e-infrastructure with the support of SURF Cooperative; Poland -Ministry of Science and Higher Education, grant No. DIR/WK/2018/11; National Science Centre, Grants No. 2013/08/M/ST9/00322, No. 2016/23/B/ST9/01635 and No. HARMONIA 5–2013/10/M/ST9/00062, UMO-2016/22/M/ST9/00198; Portugal – Portuguese national funds and FEDER funds within Programa Operacional Factores de Competitividade through Fundação para a Ciência e a Tecnologia (COMPETE); Romania – Romanian Ministry of Education and Research, the Program Nucleu within MCI (PN19150201/16N/2019 and PN19060102) and project PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018 within PNCDI III; Slovenia – Slovenian Research Agency, grants P1-0031, P1-0385, I0-0033, N1-0111; Spain – Ministerio de Economía, Industria y Competitividad (FPA2017-85114-P and PID2019-104676GB-C32), Xunta de Galicia (ED431C 2017/07), Junta de Andalucía (SOMM17/6104/UGR, P18-FR-4314) Feder Funds, RENATA Red Nacional Temática de Astropartículas (FPA2015-68783-REDT) and María de Maeztu Unit of Excellence (MDM-2016-0692); USA – Department of Energy, Contracts No. DE-AC02-07CH11359, No. DE-FR02-04ER41300, No. DE-FG02-99ER41107 and No. DE-SC0011689; National Science Foundation, Grant No. 0450696; The Grainger Foundation; Marie Curie-IRSES/EPLANET; European Particle Physics Latin American Network; University of Delaware Research Foundation (UDRF) – 2019; and UNESCO., We present a measurement of the cosmic-ray spectrum above 100 PeV using the part of the surface detector of the Pierre Auger Observatory that has a spacing of 750 m. An inflection of the spectrum is observed, confirming the presence of the so-called second-knee feature. The spectrum is then combined with that of the 1500 m array to produce a single measurement of the flux, linking this spectral feature with the three additional breaks at the highest energies. The combined spectrum, with an energy scale set calorimetrically via fluorescence telescopes and using a single detector type, results in the most statistically and systematically precise measurement of spectral breaks yet obtained. These measurements are critical for furthering our understanding of the highest energy cosmic rays., ANR-10-LABX-63 ANR-11-IDEX-0004-02, Belgium – Fonds de la Recherche Scientifique, Comisión Nacional de Energía Atómica, Département Physique Nucléaire et Corpusculaire PNC-IN2P3/CNRS, Département Sciences de l’Univers, Feder Funds, María de Maeztu Unit of Excellence MDM-2016-0692, Ministero degli Affari Esteri, RENATA Red Nacional Temática de Astropartículas FPA2015-68783-REDT, SURF, National Science Foundation 0450696, U.S. Department of Energy DE-AC02-07CH11359, DE-FG02-99ER41107, DE-FR02-04ER41300, DE-SC0011689, University of Delaware Research Foundation, United Nations Educational, Scientific and Cultural Organization, Australian Research Council, Helmholtz-Gemeinschaft, Deutsche Forschungsgemeinschaft, Fundação de Amparo à Pesquisa do Estado de São Paulo 1999/05404-3, 2010/07359-6, 2019/10151-2, Fundação para a Ciência e a Tecnologia, Bundesministerium für Bildung und Forschung, Fonds De La Recherche Scientifique - FNRS, Consejo Nacional de Investigaciones Científicas y Técnicas, Agencia Nacional de Promoción Científica y Tecnológica, Fonds Wetenschappelijk Onderzoek, Consejo Nacional de Ciencia y Tecnología 167733, Ministerie van Onderwijs, Cultuur en Wetenschap, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Ministero dell’Istruzione, dell’Università e della Ricerca, Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Conseil Régional, Île-de-France, Instituto Nazionale di Fisica Nucleare, Narodowe Centrum Nauki 2013/08/M/ST9/00322, 2013/10/M/ST9/00062, 2016/23/B/ST9/01635, UMO-2016/22/M/ST9/00198, Javna Agencija za Raziskovalno Dejavnost RS I0-0033, N1-0111, P1-0031, P1-0385, Ministerstwo Edukacji i Nauki DIR/WK/2018/11, Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro, Centre National de la Recherche Scientifique, Financiadora de Estudos e Projetos, Istituto Nazionale di Astrofisica, Universidad Nacional Autónoma de México, Ministry of Education and Research, Romania PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018, PN19060102, PN19150201/16N/2019, European Regional Development Fund, Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Ministerio de Economía, Industria y Competitividad, Gobierno de España FPA2017-85114-P, PID2019-104676GB-C32, Xunta de Galicia ED431C 2017/07, Junta de Andalucía P18-FR-4314, Ministério da Ciência, Tecnologia, Inovações e Comunicações CZ.02.1.01/0.0/0.0/16_013/0001402, CZ.02.1.01/0.0/0.0/17_049/0008422, CZ.02.1.01/0.0/0.0/18_046/0016010, LM2015038, LM2018102, MSMT CR LTT18004, Programa Operacional Temático Factores de Competitividade, Institut Lagrange de Paris

Published
2021

29. Measurement of the cosmic-ray energy spectrum above 2.5×1018 eV using the Pierre Auger Observatory

Author

Jaroslaw Stasielak, Ana Martina Botti, Marcus Niechciol, Alberto Daniel Supanitsky, Alexey Yushkov, Petr Schovánek, Pavel Horváth, Pedro Assis, Nataliia Borodai, Luis Lopes, Luis Nunez, Carla Bleve, Alberto Blanco, Katharine Mulrey, Antonella Castellina, Francesca Zuccarello, Felicia Carla Tiziana Barbato, Emanuele De Vito, Jose Alfredo Bellido Caceres, Fausto Guarino, Jeffrey Brack, Kai Daumiller, Dariusz Gora, Christian Sarmiento-Cano, Alessio Gorgi, Peter Biermann, Teresa Bister, LORENZO CACCIANIGA, Beatriz Garcia, Bruce Dawson, Alena Bakalova, MASSIMO MASTRODICASA, Edivaldo Moura Santos, Stijn Buitink, Bernardo Tomé, Ana Laura Müller, Mario BUSCEMI, Francesco Salamida, Johannes Hulsman, Henryk Wilczyński, Michael Unger, Ronald Cintra Shellard, Miguel Mostafa, Achille Nucita, Frederic Sarazin, Paul Mantsch, Ruben Conceição, Roger Clay, Lukáš Václavek, Giovanni Marsella, Markus Roth, Jakub Jurysek, Lorenzo Cazon, Eva Dos Santos, Corbin Covault, Francesco Fenu, Dalibor Nosek, Rossella Caruso, Alexandra Saftoiu, Tim Huege, Antonio CONDORELLI, Orazio Zapparrata, Jaime Alvarez-Muniz, Denise Boncioli, Guillermo Torralba Elipe, Martin Erdmann, Bruno Lazarotto Lago, Carlos José Todero Peixoto, Geraldina Golup, Jan Pękala, Maximilian Stadelmaier, Raul Sarmento, Enrique Varela, Antoine Letessier selvon, Vincenzo Rizi, Eleonora Guido, Pedro T. Abreu, Rafael Alves Batista, Arjen Van Vliet, and Jan Ebr

Subjects
Pierre Auger Observatory, Physics, Spectral index, 010308 nuclear & particles physics, Hadron, Flux, Cosmic ray, Astrophysics, 01 natural sciences, Flattening, 0103 physical sciences, 010306 general physics, Anisotropy, Zenith
Abstract

We report a measurement of the energy spectrum of cosmic rays for energies above 2.5×1018 eV based on 215,030 events recorded with zenith angles below 60°. A key feature of the work is that the estimates of the energies are independent of assumptions about the unknown hadronic physics or of the primary mass composition. The measurement is the most precise made hitherto with the accumulated exposure being so large that the measurements of the flux are dominated by systematic uncertainties except at energies above 5×1019 eV. The principal conclusions are(1) The flattening of the spectrum near 5×1018 eV, the so-called "ankle,"is confirmed.(2) The steepening of the spectrum at around 5×1019 eV is confirmed.(3) A new feature has been identified in the spectrum: in the region above the ankle the spectral index γ of the particle flux (∝E-γ) changes from 2.51±0.03 (stat)±0.05 (syst) to 3.05±0.05 (stat)±0.10 (syst) before changing sharply to 5.1±0.3 (stat)±0.1 (syst) above 5×1019 eV.(4) No evidence for any dependence of the spectrum on declination has been found other than a mild excess from the Southern Hemisphere that is consistent with the anisotropy observed above 8×1018 eV.

Published
2020

30. Features of the Energy Spectrum of Cosmic Rays above 2.5×1018 eV Using the Pierre Auger Observatory

Author

Jaroslaw Stasielak, Ana Martina Botti, Marcus Niechciol, Alberto Daniel Supanitsky, Alexey Yushkov, Petr Schovánek, Toshihiro Fujii, Pavel Horváth, Pedro Assis, Nataliia Borodai, Luis Lopes, Luis Nunez, Carla Bleve, Alberto Blanco, Katharine Mulrey, Antonella Castellina, Francesca Zuccarello, Felicia Carla Tiziana Barbato, Emanuele De Vito, Jose Alfredo Bellido Caceres, Fausto Guarino, Jeffrey Brack, Kai Daumiller, Dariusz Gora, Christian Sarmiento-Cano, Carola Dobrigkeit Chinellato, Alessio Gorgi, Peter Biermann, Teresa Bister, LORENZO CACCIANIGA, Beatriz Garcia, Bruce Dawson, Alena Bakalova, MASSIMO MASTRODICASA, Edivaldo Moura Santos, Stijn Buitink, Bernardo Tomé, Ana Laura Müller, Mario BUSCEMI, Francesco Salamida, Johannes Hulsman, Henryk Wilczyński, Michael Unger, Ronald Cintra Shellard, Miguel Mostafa, Achille Nucita, Frederic Sarazin, Paul Mantsch, Ruben Conceição, Roger Clay, Lukáš Václavek, Giovanni Marsella, Markus Roth, Jakub Jurysek, Lorenzo Cazon, Eva Dos Santos, Corbin Covault, Francesco Fenu, Dalibor Nosek, Rossella Caruso, Alexandra Saftoiu, Tim Huege, Antonio CONDORELLI, Orazio Zapparrata, Jaime Alvarez-Muniz, Denise Boncioli, Guillermo Torralba Elipe, Martin Erdmann, Bruno Lazarotto Lago, Carlos José Todero Peixoto, Geraldina Golup, Jan Pękala, Maximilian Stadelmaier, Raul Sarmento, Enrique Varela, Antoine Letessier selvon, Vincenzo Rizi, Eleonora Guido, Pedro T. Abreu, Rafael Alves Batista, Arjen Van Vliet, and Jan Ebr

Subjects
010308 nuclear & particles physics, 0103 physical sciences, General Physics and Astronomy, 010306 general physics, 01 natural sciences
Published
2020

31. Studies on the response of a water-Cherenkov detector of the Pierre Auger Observatory to atmospheric muons using an RPC hodoscope

Author

A. Zepeda, Pedro Assis, H. Martinez, A. Etchegoyen, Dariusz Gora, Bjarni Pont, Alan Coleman, B. Tome, Peter Hansen, F. Guarino, John Matthews, Peter Buchholz, S. J. Saffi, D. Lo Presti, S. J. De Jong, B. García, R. López, Karen S. Caballero-Mora, G. Cataldi, V. Scherini, Martin Erdmann, G. Matthiae, J. de Jesús, Frank G. Schröder, Antonio Bueno, A. Streich, Gioacchino Alex Anastasi, M. Wirtz, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, P. Abreu, D. Ravignani, Roger W Clay, Marco Aglietta, Marko Zavrtanik, E. Santos, Jarryd A. Day, G. De Mauro, F. Riehn, Marina Scornavacche, Alexandra Saftoiu, Tiina Suomijarvi, F. Pedreira, Raul Sarmento, Felix Schlüter, Martin Vacula, J. Rautenberg, Q. Luce, Gualberto Avila, Martín Miguel Freire, Fabian Gobbi, Jiri Blazek, Lorenzo Caccianiga, Denis Stanca, I. Lhenry-Yvon, Miroslav Pech, M. Pothast, Markus Roth, D. Nitz, A.C. Cobos Cerutti, J. R. T. de Mello Neto, Paul Sommers, A. Blanco, Marcus Niechciol, B. Vargas Cárdenas, J. Pallotta, L. R. Wiencke, G. Marsella, F. Sánchez, Heino Falcke, Maximilian Stadelmaier, Jesús Peña-Rodríguez, Carla Bleve, Rodrigo Guedes Lang, B. Andrada, P. Horvath, Isabel Goos, D. Heck, John Farmer, Jonathan Biteau, A. Insolia, M. Kleifges, A.D. Supanitsky, J. Pȩkala, Antonio Condorelli, Christine Peters, Maria-Teresa Dova, M. R. Hampel, Valerio Verzi, J. Vicha, A. M. Botti, Niraj Dhital, P. Tobiska, Sofia Andringa, Julian Kemp, Luis Villaseñor, R. Conceição, A. Weindl, S. Querchfeld, Miroslav Hrabovský, T. Huege, M. del Río, Nicolás González, Jeffrey Brack, A.L. Garcia Vegas, M. Schimp, Marvin Gottowik, Maria Rita Coluccia, Maximilian Reininghaus, M.A. Leigui de Oliveira, Olaf Scholten, Gaia Silli, Humberto Ibarguen Salazar, D. Mockler, L. Bonneau Arbeletche, A. Di Matteo, Eric Mayotte, A. Haungs, A. Filipčič, G. Torralba Elipe, I. Valiño, Olena Tkachenko, M. I. Micheletti, B. C. Manning, P. Ruehl, Ralf Ulrich, M. Gómez Berisso, L. Valore, B. Wundheiler, L. Lopes, Roberto Mussa, J. Šupík, Carlo Ventura, F. Sarazin, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, David Schmidt, S. Schröder, Italo Epicoco, S. Petrera, Marc Weber, Charles Timmermans, Hernán Asorey, R.C. dos Anjos, R.C. Shellard, Adriana Vásquez-Ramírez, J. F. Valdés Galicia, M. Palatka, Mario Buscemi, Jörg R. Hörandel, P. Mantsch, J. Hulsman, Julien Manshanden, Dusan Mandat, Lukáš Vaclavek, H. J. Mathes, I. De Mitri, Stanislav Michal, G. Mancarella, François Montanet, G. Golup, B. Keilhauer, Sullivan Marafico, Vladimir Lenok, L. Perrone, Francesco Fenu, Ladislav Chytka, Gaetano Salina, Hernan Wahlberg, Miguel Mostafa, Violet M. Harvey, Andres Travaini, E. Varela, J.D. Sanabria Gomez, D. Harari, L. Nožka, J. Chudoba, S. J. Sciutto, J. Rodriguez Rojo, Fridtjof Feldbusch, Marcel Köpke, M. Platino, C. M. Schäfer, Maria Giller, R. Squartini, Alfred Müller, Marco Giammarchi, Juan Miguel Carceller, P. Savina, Eleonora Guido, W. Rodrigues de Carvalho, Flavia Gesualdi, Alex Kääpä, Enrique Zas, A. Parra, Alena Bakalova, J. Stasielak, Massimo Mastrodicasa, R. M. de Almeida, Teresa Bister, E. De Vito, R.J. Barreira Luz, Alina Mihaela Badescu, Dalibor Nosek, Fernando Contreras, Brian Fick, Samo Stanič, Giovanni Consolati, Cristina Galea, P. Ristori, M. Trini, K. Choi, Martina Bohacova, G. Medina-Tanco, A. Tapia, Octavian Sima, A. Cancio, H. Gemmeke, R. Halliday, Nataliia Borodai, M. Unger, M. L. Díaz Castro, G. Farrar, M.P. Panetta, Petr Schovanek, Juan Pablo Gongora, Christian Sarmiento-Cano, Francesca Zuccarello, Luis A. Anchordoqui, I. Allekotte, M. J. Roncoroni, Valerio Pirronello, H. Schieler, Q. Dorosti, Philipp Papenbreer, C. J. Todero Peixoto, Karl-Heinz Kampert, L. Calcagni, Kai Daumiller, Antonella Castellina, A. C. Fauth, F. Salamida, A. Yushkov, A. Fuster, A. Puyleart, L. Nellen, Zbigniew Szadkowski, Michael Prouza, Corinne Berat, Carla Bonifazi, Rodrigo Pelayo, Denise Boncioli, D. Melo, Stijn Buitink, M. Risse, V. Novotny, Trent D. Grubb, A. Taboada, Jose A. Bellido, C. Morello, Rossella Caruso, Fabio Convenga, A. Lucero, Fernando Catalani, Caterina Trimarelli, M. A. Muller, Juan Manuel Figueira, H. Wilczyński, Roberta Colalillo, P.F. Gómez Vitale, I.D. Vergara Quispe, A. G. Mariazzi, A. Aab, R. Sato, Peter L. Biermann, G. P. Guedes, Toshihiro Fujii, Paolo Privitera, Jakub Juryšek, G. Kukec Mezek, Alessio Gorgi, M. E. Bertaina, A. Menshikov, P. Travnicek, J. Debatin, Orazio Zapparrata, Carola Dobrigkeit, M. Muzio, Steffen Hahn, Juan Carlos D'Olivo, T. Pierog, Esteban Roulet, Justin M. Albury, Alan Watson, M. Perlin, Mihai Niculescu-Oglinzanu, J. Alvarez Castillo, Matias Tueros, Luis A. Nunez, Piera Luisa Ghia, Jeffrey A. Johnsen, B. L. Lago, Günter Sigl, P. Stassi, Radomir Smida, A. Machado Payeras, Paula Gina Isar, Fernando Gollan, E. M. Santos, R. Alves Batista, Bruce R. Dawson, P.O. Mazur, V. de Souza, K.-H. Becker, M. Pimenta, P.R. Araújo Ferreira, Tobias Winchen, Florian Lukas Briechle, Max Malacari, J. Perez Armand, Claudio Galelli, Jose Chinellato, Ioana Caracas, A. Letessier-Selvon, Lorenzo Cazon, A. van Vliet, David Wittkowski, Danielle LaHurd, Olivier Deligny, Tomáš Fodran, R. Lorek, M. Urban, W. M. Namasaka, A. C. Rovero, Ugo Giaccari, Alexandru Balaceanu, M. Suárez-Durán, Carla Aramo, Julien Souchard, D. Martello, M. Ziolkowski, O. Martínez Bravo, K. Mulrey, Silvia Mollerach, N. Fazzini, Ioana Codrina Maris, Jonas Glombitza, F. C. T. Barbato, D. Zavrtanik, Serguei Vorobiov, G. C. Hill, Jorge F. Soriano, Ralph Engel, Marcos Cerda, J. Ridky, Darko Veberič, J. Kleinfeller, Carlos Escobar, Kevin-Druis Merenda, M. Schimassek, C. Hojvat, Jan Ebr, Jacco Vink, H.O. Klages, A. A. Nucita, G. Parente, Fabrizia Canfora, L. Zehrer, J. de Oliveira, Alejandro Almela, Thomas Bretz, V. Rizi, Corbin Covault, Lino Miramonti, D. de Oliveira Franco, Xavier Bertou, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Castillo, J. Alvarez, Alvarez-Muñiz, J., Batista, R. Alve, Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ferreira, P. R. Araújo, Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Luz, R. J. Barreira, Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blanco, A., Blazek, J., Bleve, C., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Botti, A. M., Brack, J., Bretz, T., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Calcagni, L., Cancio, A., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobo, Colalillo, R., Coleman, A., Coluccia, M. R., Conceição, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesús, J., de Jong, S. J., Mauro, G. De, Neto, J. R. T. de Mello, Mitri, I. De, de Oliveira, J., Franco, D. de Oliveira, de Souza, V., Vito, E. De, Debatin, J., Río, M. del, Deligny, O., Dhital, N., Matteo, A. Di, Castro, M. L. Díaz, Dobrigkeit, C., D'Olivo, J. C., Dorosti, Q., Anjos, R. C. do, Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipčič, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., García, B., Vegas, A. L. Garcia, Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, N., Goos, I., Góra, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Halliday, R., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Johnsen, J. A., Jurysek, J., Kääpä, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Köpke, M., Mezek, G. Kukec, Lago, B. L., Lahurd, D., Lang, R. G., de Oliveira, M. A. Leigui, Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Presti, D. Lo, Lopes, L., López, R., Lorek, R., Luce, Q., Lucero, A., Payeras, A. Machado, Malacari, M., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinez, H., Bravo, O. Martínez, Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mockler, D., Mollerach, S., Montanet, F., Morello, C., Mostafá, M., Müller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A, Núñez, L. A., Palatka, M., Pallotta, J., Panetta, M. P., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pȩkala, J., Pelayo, R., Peña-Rodriguez, J., Armand, J. Perez, Perlin, M., Perrone, L., Peters, C., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Ristori, P., Rizi, V., de Carvalho, W. Rodrigue, Rojo, J. Rodriguez, Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schlüter, F., Schmidt, D., Scholten, O., Schovánek, P., Schröder, F. G., Schröder, S., Sciutto, S. J., Scornavacche, M., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Šmída, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanič, S., Stasielak, J., Stassi, P., Streich, A., Suárez-Durán, M., Sudholz, T., Suomijärvi, T., Supanitsky, A. D., Šupík, J., Szadkowski, Z., Taboada, A., Tapia, A., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Elipe, G. Torralba, Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Urban, M., Vaclavek, L., Vacula, M., Galicia, J. F. Valdé, Valiño, I., Valore, L., Vliet, A. van, Varela, E., Cárdenas, B. Varga, Vásquez-Ramírez, A., Veberič, D., Ventura, C., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Villaseñor, L., Vink, J., Vorobiov, S., Wahlberg, H., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczyński, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Ziolkowski, M., Zuccarello, F., Castillo, J. A., Alvarez-Muniz, J., Batista, R. A., Ferreira, P. R. A., Luz, R. J. B., Bohacova, M., Arbeletche, L. B., Cerutti, A. C. C., Conceicao, R., De Almeida, R. M., De Jesus, J., De Jong, S. J., Mauro, G. D., Neto, J. R. T. D. M., De Mitri, I., De Oliveira, J., De Oliveira Franco, D., De Souza, V., De Vito, E., Del Rio, M., Di Matteo, A., Castro, M. L. D., Dos Anjos, R. C., Filipcic, A., Garcia, B., Vegas, A. L. G., Berisso, M. G., Vitale, P. F. G., Gonzalez, N., Gora, D., Horandel, J. R., Hrabovsky, M., Kaapa, A., Kopke, M., Mezek, G. K., De Oliveira, M. A. L., Presti, D. L., Lopez, R., Payeras, A. M., Maris, I. C., Bravo, O. M., Mostafa, M., Muller, A. L., Nozka, L., Nucita, A., Nunez, L. A., Pkala, J., Pena-Rodriguez, J., Armand, J. P., De Carvalho, W. R., Rojo, J. R., Gomez, J. D. S., Sanchez, F., Schafer, C. M., Schluter, F., Schovanek, P., Schroder, F. G., Schroder, S., Smida, R., Stanic, S., Suarez-Duran, M., Suomijarvi, T., Supik, J., Peixoto, C. J. T., Tome, B., Elipe, G. T., Galicia, J. F. V., Valino, I., Vliet, A. V., Cardenas, B. V., Vasquez-Ramirez, A., Veberic, D., Quispe, I. D. V., Villasenor, L., Wilczynski, H., High Energy Astrophys. & Astropart. Phys (API, FNWI), Research unit Astroparticle Physics, Physics, Elementary Particle Physics, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Castillo J.A., Alvarez-Muniz J., Batista R.A., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Ferreira P.R.A., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Luz R.J.B., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blanco A., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Arbeletche L.B., Borodai N., Botti A.M., Brack J., Bretz T., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Calcagni L., Cancio A., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cerutti A.C.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., De Almeida R.M., De Jesus J., De Jong S.J., Mauro G.D., Neto J.R.T.D.M., De Mitri I., De Oliveira J., De Oliveira Franco D., De Souza V., De Vito E., Debatin J., Del Rio M., Deligny O., Dhital N., Di Matteo A., Castro M.L.D., Dobrigkeit C., D'Olivo J.C., Dorosti Q., Dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Vegas A.L.G., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Berisso M.G., Vitale P.F.G., Gongora J.P., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Halliday R., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Mezek G.K., Lago B.L., Lahurd D., Lang R.G., De Oliveira M.A.L., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Presti D.L., Lopes L., Lopez R., Lorek R., Luce Q., Lucero A., Payeras A.M., Malacari M., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Bravo O.M., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mockler D., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Panetta M.P., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pkala J., Pelayo R., Pena-Rodriguez J., Armand J.P., Perlin M., Perrone L., Peters C., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Ristori P., Rizi V., De Carvalho W.R., Rojo J.R., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Gomez J.D.S., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Sciutto S.J., Scornavacche M., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Timmermans C., Tkachenko O., Tobiska P., Peixoto C.J.T., Tome B., Elipe G.T., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Urban M., Vaclavek L., Vacula M., Galicia J.F.V., Valino I., Valore L., Vliet A.V., Varela E., Cardenas B.V., Vasquez-Ramirez A., Veberic D., Ventura C., Quispe I.D.V., Verzi V., Vicha J., Villasenor L., Vink J., Vorobiov S., Wahlberg H., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., Ziolkowski M., and Zuccarello F.

Subjects
Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, Astronomy, 01 natural sciences, 030218 nuclear medicine & medical imaging, law.invention, 0302 clinical medicine, law, Observatory, atmosphere [muon], Instrumentation, physics.ins-det, Mathematical Physics, Large detector-systems performance, Physics, Instrumentation et méthodes en physique, Performance of high energy physics detectors, Data reduction methods, Large detector systems for particle and astroparticle physics, Detector, Settore FIS/01 - Fisica Sperimentale, Astrophysics::Instrumentation and Methods for Astrophysics, resistive plate chamber, Instrumentation and Detectors (physics.ins-det), trajectory [muon], Auger, observatory, muon: atmosphere, Astrophysics - Instrumentation and Methods for Astrophysics, atmosphere [showers], Cherenkov detector, air, Cherenkov counter: water, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], FOS: Physical sciences, Cosmic ray, muon: trajectory, Nuclear physics, 03 medical and health sciences, Hodoscope, Data reduction method, 0103 physical sciences, Calibration, High Energy Physics, ddc:610, cosmic radiation: UHE, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Instrumentation and Methods for Astrophysics (astro-ph.IM), Zenith, Ciencias Exactas, Pierre Auger Observatory, showers: atmosphere, 010308 nuclear & particles physics, water [Cherenkov counter], hodoscope, Física, Autres mathématiques, stability, calibration, Data reduction methods, Large detector systems for particle and astroparticle physics, Large detector-systems performance, Performance of High Energy Physics Detectors, Experimental High Energy Physics, Large detector systems for particle and astroparticle physic, High Energy Physics::Experiment, RAIOS CÓSMICOS, astro-ph.IM
Abstract

Extensive air showers, originating from ultra-high energy cosmic rays, have been successfully measured through the use of arrays of water-Cherenkov detectors (WCDs). Sophisticated analyses exploiting WCD data have made it possible to demonstrate that shower simulations, based on different hadronic-interaction models, cannot reproduce the observed number of muons at the ground. The accurate knowledge of the WCD response to muons is paramount in establishing the exact level of this discrepancy. In this work, we report on a study of the response of a WCD of the Pierre Auger Observatory to atmospheric muons performed with a hodoscope made of resistive plate chambers (RPCs), enabling us to select and reconstruct nearly 600 thousand single muon trajectories with zenith angles ranging from 0º to 55º. Comparison of distributions of key observables between the hodoscope data and the predictions of dedicated simulations allows us to demonstrate the accuracy of the latter at a level of 2%. As the WCD calibration is based on its response to atmospheric muons, the hodoscope data are also exploited to show the long-term stability of the procedure., La lista completa de autores que integran el documento puede consultarse en el archivo., Facultad de Ciencias Exactas, Instituto de Física La Plata

Published
2020
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32. A 3-Year Sample of Almost 1,600 Elves Recorded Above South America by the Pierre Auger Cosmic-Ray Observatory

Author

B. García, M. L. Díaz Castro, G. Farrar, R. López, Karen S. Caballero-Mora, Francesca Zuccarello, Hernan Wahlberg, Q. Luce, Jose Chinellato, P. H. Nguyen, Martin Erdmann, Octavian Sima, J. Kleinfeller, H. J. Mathes, Z. Zong, G. Matthiae, R. R. Prado, F. Diogo, E. M. Santos, M. Schauer, A. Streich, Gioacchino Alex Anastasi, Stanislav Michal, A. Taboada, A. Letessier-Selvon, A. Parra, Antonio Bueno, Daniel Kuempel, M. Wirtz, Isabel Goos, Lorenzo Cazon, R. M. de Almeida, Kevin-Druis Merenda, D. Heck, G. P. Guedes, Roger W Clay, A. van Vliet, Frank G. Schröder, Toshihiro Fujii, P. Ristori, M. del Río, Bruce R. Dawson, Tim Huege, M. Trini, P.F. Gómez Vitale, Gualberto Avila, P.O. Mazur, David Wittkowski, J. Rodriguez Rojo, Jakub Juryšek, J. Debatin, Ivone F. M. Albuquerque, Angela V. Olinto, G. Salina, Danielle LaHurd, Olivier Deligny, Charles Timmermans, Lukas Middendorf, Fridtjof Feldbusch, Ioana Codrina Maris, M. I. Micheletti, Antonio Condorelli, R. Lorek, Giuseppe De Mauro, J. F. Valdés Galicia, G. C. Hill, Ugo Giaccari, Jorge F. Soriano, Enrique Zas, A. Cancio, Ralph Engel, Rodrigo Pelayo, Q. Dorosti, J. Ridky, Stijn Buitink, Christine Peters, M. Scornavacche, M. Zavrtanik, M. Schimp, M. Risse, Juan Carlos D'Olivo, T. Pierog, Justin M. Albury, Max Malacari, Lili Yang, Markus Roth, I. Allekotte, John Farmer, Piotr Homola, Fernando Contreras, E.M. Holt, Giovanni Consolati, B. C. Manning, Jonathan Blazek, R. Ramos-Pollan, L. Nellen, Piera Luisa Ghia, M. Josebachuili, C. Morello, A. Tapia, Jonathan Biteau, Dariusz Gora, Maria-Teresa Dova, Giovanni Marsella, D. Nosek, Luis A. Anchordoqui, Benedikt Zimmermann, Rúben Conceição, E. Santos, Alessio Gorgi, A. C. Fauth, Vladimir Lenok, L. Perrone, M. A. Leigui de Oliveira, A.M. van den Berg, Darko Veberič, G. Torralba Elipe, Philipp Papenbreer, G. Parente, Fabrizia Canfora, A. Aab, R. Krause, L. Valore, G. Morlino, Hernán Asorey, A. Bridgeman, Esteban Roulet, Petr Travnicek, Carla Bonifazi, S. J. Saffi, Alan Coleman, Trent D. Grubb, Jose A. Bellido, Carola Dobrigkeit, L. Zehrer, Thomas Harrison, D. Melo, R. Legumina, G. Kukec Mezek, M. J. Roncoroni, D. Nitz, Nicolas Martin Gonzalez, Peter L. Biermann, R.C. dos Anjos, L. A. S. Pereira, M.P. Panetta, Petr Schovanek, A. Puyleart, Corinne Berat, M. Giller, S. Baur, M. Stolpovskiy, Juan Manuel Figueira, Roberta Colalillo, M. Palatka, Jan Pękala, A. G. Mariazzi, M. Perlin, Luis Villaseñor, Alan Watson, M. E. Bertaina, A. Menshikov, F. Pedreira, J. Phuntsok, A. Weindl, Raul Sarmento, Paolo Privitera, D. Lo Presti, S. J. De Jong, Patricia María Hansen, Marvin Gottowik, N. Kemmerich, Martina Bohacova, K.-H. Becker, M. Pimenta, Eric Mayotte, Jeffrey A. Johnsen, S. Quinn, Xavier Bertou, Felix Schlüter, Mihai Niculescu-Oglinzanu, A. Zepeda, L. R. Wiencke, I.D. Vergara Quispe, J. Alvarez Castillo, P. Ruehl, Pedro Assis, Maximilian Reininghaus, M. Schimassek, J. de Oliveira, Alejandro Almela, C. Hojvat, Marco Giammarchi, Jan Ebr, Fabian Gobbi, Jarryd A. Day, A. Etchegoyen, David Schmidt, A. M. Botti, Roberto Mussa, M. Gómez Berisso, R. C. Shellard, Juan Pablo Gongora, Günter Sigl, Tobias Winchen, R. Sato, Florian Lukas Briechle, Denis Stanca, P. Stassi, Paul Sommers, Radomir Smida, F. Guarino, John Matthews, A. Blanco, O. C. Lippmann, A.C. Cobos Cerutti, B. Vargas Cárdenas, T. Suomijärvi, Peter Buchholz, J. Pallotta, C. Sarmiento-Cano, Jacco Vink, Thomas Bretz, H.O. Klages, Corbin Covault, J. R. T. de Mello Neto, Miroslav Hrabovský, M. Urban, M. Mastrodicasa, Matias Tueros, François Montanet, Lourenco Lopes, Mario Buscemi, B. L. Lago, S. Schröder, M. J. Cooper, F. Sánchez, V. de Souza, A. C. Rovero, Niraj Dhital, J. Rautenberg, C. Bleve, M. Wiedeński, Marco Aglietta, Dusan Mandat, I. Valiño, Matías Rolf Hampel, Alexandru Balaceanu, A. Haungs, Francesco Fenu, A. Kuotb Awad, S. G. Blaess, Lino Miramonti, A. A. Nucita, Jaime Alvarez-Muñiz, Jesús Peña-Rodríguez, P. Abreu, B. Mitrica, D. Ravignani, Heino Falcke, V. Novotny, Alexandru Gherghel-Lascu, Eleonora Guido, Rossella Caruso, A. Lucero, Fernando Catalani, S. Mathys, Luis A. Nunez, I. Jandt, Ralf Ulrich, Marcio Aparecido Muller, M. Suárez-Durán, Carla Aramo, Jörg R. Hörandel, P. Mantsch, J. Vicha, Z. Szadkowski, Daniela Mockler, Vincenzo Rizi, Julien Souchard, D. Martello, I. Lhenry-Yvon, Miroslav Pech, M. Ziolkowski, M. Platino, F.O. de Oliveira Salles, P. Savina, G. Golup, Paula Gina Isar, Maria Rita Coluccia, Bruno Daniel, G. Mancarella, B. Keilhauer, Pavel Horvath, W. Rodrigues de Carvalho, Marcus Niechciol, Silvia Mollerach, O. Martínez Bravo, Julian Kemp, Rodrigo Guedes Lang, Belén Andrada, S. J. Sciutto, P. van Bodegom, S. Müller, Juan Miguel Carceller, Alex Kääpä, S. Querchfeld, Nataliia Borodai, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, A. Fuster, Sofia Andringa, H. Gemmeke, M. Unger, A. D. Supanitsky, J. Šupík, Carlo Ventura, Andrej Dundovic, Lorenzo Caccianiga, B. Wundheiler, Andres Travaini, Gregory R Snow, E. Varela, J.D. Sanabria Gomez, J. Chudoba, H. Schieler, Karl-Heinz Kampert, Ladislav Chytka, L. Calcagni, Kai Daumiller, Antonella Castellina, Alena Bakalova, J. Stasielak, S. Coutu, Gaia Silli, P. Heimann, Serguei Vorobiov, A. Filipčič, Federico Suarez, O. A. Taborda, C. Porowski, H. Martinez, F. Sarazin, Marcos Cerda, Denise Boncioli, G. Cataldi, V. Scherini, Valerio Verzi, B. Tome, Alexandra Saftoiu, Thomas Hebbeker, S. Petrera, Marc Weber, Sergio Dasso, Tristan Sudholz, Ivan De Mitri, Martín Miguel Freire, Jeffrey Brack, Olaf Scholten, Humberto Ibarguen Salazar, F. Riehn, Miguel Mostafa, C. O. Escobar, A. Insolia, M. Kleifges, D. Zavrtanik, A. López Casado, Samo Stanič, Dariusz Glas, Bjarni Pont, R.J. Barreira Luz, Johannes Schumacher, Violet M. Harvey, D. Harari, F. Salamida, A. Yushkov, L.P. Ferreyro, Alina Mihaela Badescu, M. Prouza, R. Squartini, Alfred Müller, G. Medina-Tanco, R. Halliday, J. Hulsman, J. Poh, Valerio Pirronello, C. J. Todero Peixoto, L. Noža, H. Wilczyński, Aab A., Abreu P., Aglietta M., Albuquerque I.F.M., Albury J.M., Allekotte I., Almela A., Alvarez Castillo J., Alvarez-Muniz J., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Baur S., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Biteau J., Blaess S.G., Blanco A., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Borodai N., Botti A.M., Brack J., Bretz T., Bridgeman A., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Calcagni L., Cancio A., Canfora F., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Cooper M.J., Coutu S., Covault C.E., Daniel B., Dasso S., Daumiller K., Dawson B.R., Day J.A., de Almeida R.M., de Jong S.J., Mauro G., de Mello Neto J.R.T., Mitri I., de Oliveira J., de Oliveira Salles F.O., de Souza V., Debatin J., del Rio M., Deligny O., Dhital N., Diaz Castro M.L., Diogo F., Dobrigkeit C., D'Olivo J.C., Dorosti Q., dos Anjos R.C., Dova M.T., Dundovic A., Ebr J., Engel R., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Ferreyro L.P., Figueira J.M., Filipcic A., Freire M.M., Fujii T., Fuster A., Garcia B., Gemmeke H., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glas D., Glombitza J., Gobbi F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Halliday R., Hampel M.R., Hansen P., Harari D., Harrison T.A., Harvey V.M., Haungs A., Hebbeker T., Heck D., Heimann P., Hill G.C., Hojvat C., Holt E.M., Homola P., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Jandt I., Johnsen J.A., Josebachuili M., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemmerich N., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Krause R., Kuempel D., Kukec Mezek G., Kuotb Awad A., Lago B.L., LaHurd D., Lang R.G., Legumina R., Leigui de Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lippmann O.C., Lo Presti D., Lopes L., Lopez R., Lopez Casado A., Lorek R., Luce Q., Lucero A., Malacari M., Mancarella G., Mandat D., Manning B.C., Mantsch P., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Mathys S., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Middendorf L., Miramonti L., Mitrica B., Mockler D., Mollerach S., Montanet F., Morello C., Morlino G., Mostafa M., Muller A.L., Muller M.A., Muller S., Mussa R., Nellen L., Nguyen P.H., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Noza L., Nucita A., Nunez L.A., Olinto A., Palatka M., Pallotta J., Panetta M.P., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pekala J., Pelayo R., Pena-Rodriguez J., Pereira L.A.S., Perlin M., Perrone L., Peters C., Petrera S., Phuntsok J., Pierog T., Pimenta M., Pirronello V., Platino M., Poh J., Pont B., Porowski C., Prado R.R., Privitera P., Prouza M., Puyleart A., Querchfeld S., Quinn S., Ramos-Pollan R., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Ristori P., Rizi V., Rodrigues de Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schauer M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schumacher J., Sciutto S.J., Scornavacche M., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Snow G.R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stanca D., Stanic S., Stasielak J., Stassi P., Stolpovskiy M., Streich A., Suarez F., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Taborda O.A., Tapia A., Timmermans C., Todero Peixoto C.J., Tome B., Torralba Elipe G., Travaini A., Travnicek P., Trini M., Tueros M., Ulrich R., Unger M., Urban M., Valdes Galicia J.F., Valino I., Valore L., van Bodegom P., van den Berg A.M., van Vliet A., Varela E., Vargas Cardenas B., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Villasenor L., Vink J., Vorobiov S., Wahlberg H., Watson A.A., Weber M., Weindl A., Wiedenski M., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yang L., Yushkov A., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., Zimmermann B., Ziolkowski M., Zong Z., Zuccarello F., Aab, A., Abreu, P., Aglietta, M., Albuquerque, I. F. M., Albury, J. M., Allekotte, I., Almela, A., Alvarez Castillo, J., Alvarez-Muniz, J., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Baur, S., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Biteau, J., Blaess, S. G., Blanco, A., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Bridgeman, A., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Calcagni, L., Cancio, A., Canfora, F., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Cooper, M. J., Coutu, S., Covault, C. E., Daniel, B., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jong, S. J., Mauro, G., de Mello Neto, J. R. T., Mitri, I., de Oliveira, J., de Oliveira Salles, F. O., de Souza, V., Debatin, J., del Rio, M., Deligny, O., Dhital, N., Diaz Castro, M. L., Diogo, F., Dobrigkeit, C., D'Olivo, J. C., Dorosti, Q., dos Anjos, R. C., Dova, M. T., Dundovic, A., Ebr, J., Engel, R., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Ferreyro, L. P., Figueira, J. M., Filipcic, A., Freire, M. M., Fujii, T., Fuster, A., Garcia, B., Gemmeke, H., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glas, D., Glombitza, J., Gobbi, F., Golup, G., Gomez Berisso, M., Gomez Vitale, P. F., Gongora, J. P., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Halliday, R., Hampel, M. R., Hansen, P., Harari, D., Harrison, T. A., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Heimann, P., Hill, G. C., Hojvat, C., Holt, E. M., Homola, P., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Jandt, I., Johnsen, J. A., Josebachuili, M., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemmerich, N., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Krause, R., Kuempel, D., Kukec Mezek, G., Kuotb Awad, A., Lago, B. L., Lahurd, D., Lang, R. G., Legumina, R., Leigui de Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lippmann, O. C., Lo Presti, D., Lopes, L., Lopez, R., Lopez Casado, A., Lorek, R., Luce, Q., Lucero, A., Malacari, M., Mancarella, G., Mandat, D., Manning, B. C., Mantsch, P., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Martinez Bravo, O., Mastrodicasa, M., Mathes, H. J., Mathys, S., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Middendorf, L., Miramonti, L., Mitrica, B., Mockler, D., Mollerach, S., Montanet, F., Morello, C., Morlino, G., Mostafa, M., Muller, A. L., Muller, M. A., Muller, S., Mussa, R., Nellen, L., Nguyen, P. H., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Noza, L., Nucita, A., Nunez, L. A., Olinto, A., Palatka, M., Pallotta, J., Panetta, M. P., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pekala, J., Pelayo, R., Pena-Rodriguez, J., Pereira, L. A. S., Perlin, M., Perrone, L., Peters, C., Petrera, S., Phuntsok, J., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Poh, J., Pont, B., Porowski, C., Prado, R. R., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Quinn, S., Ramos-Pollan, R., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Ristori, P., Rizi, V., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schauer, M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schumacher, J., Sciutto, S. J., Scornavacche, M., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Snow, G. R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Stolpovskiy, M., Streich, A., Suarez, F., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Taborda, O. A., Tapia, A., Timmermans, C., Todero Peixoto, C. J., Tome, B., Torralba Elipe, G., Travaini, A., Travnicek, P., Trini, M., Tueros, M., Ulrich, R., Unger, M., Urban, M., Valdes Galicia, J. F., Valino, I., Valore, L., van Bodegom, P., van den Berg, A. M., van Vliet, A., Varela, E., Vargas Cardenas, B., Veberic, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Villasenor, L., Vink, J., Vorobiov, S., Wahlberg, H., Watson, A. A., Weber, M., Weindl, A., Wiedenski, M., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yang, L., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Zimmermann, B., Ziolkowski, M., Zong, Z., Zuccarello, F., Physics, ITA, and Research unit Astroparticle Physics

Subjects
010504 meteorology & atmospheric sciences, Astronomy, Field of view, 010502 geochemistry & geophysics, 01 natural sciences, 7. Clean energy, Auger, lcsh:QB1-991, Observatory, ultraviolet, Storm, ddc:550, UHE Cosmic Rays, time resolution, Cosmic-ray observatory, Physics, lcsh:QE1-996.5, astro-ph, Geology, width [beam], Ionosphere, lcsh:Astronomy, UHE [cosmic radiation], Environmental Science (miscellaneous), horizon, Lightning, ddc:530, High Energy Physics, 0105 earth and related environmental sciences, fluorescence [detector], background, Física, sensitivity, optics, lcsh:Geology, Elves, UV fluorescence detectors, Thunderstorm, 13. Climate action, Experimental High Energy Physics, network, General Earth and Planetary Sciences, Elves
Abstract

The time and location of the 1,598 verified and reconstructed elves, used for the analysis showcased in this paper, are publicly available on the website of the Pierre Auger Observatory (https://www.auger.org/ index.php/science/data). We wish to thank the World Wide Lightning Location Network (http://wwlln.net), a collaboration among over 50 universities and institutions, for providing the lightning location data used in this paper. We acknowledge Robert Marshall for providing one of the most advanced elve simulations to the public, a key tool in understanding the elves observed by the Pierre Auger Observatory. The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargüe., Elves are a class of transient luminous events, with a radial extent typically greater than 250 km, that occur in the lower ionosphere above strong electrical storms. We report the observation of 1,598 elves, from 2014 to 2016, recorded with unprecedented time resolution (100 ns) using the fluorescence detector (FD) of the Pierre Auger Cosmic-Ray Observatory. The Auger Observatory is located in the Mendoza province of Argentina with a viewing footprint for elve observations of 3 · 106 km2, reaching areas above the Pacific and Atlantic Oceans, as well as the Córdoba region, which is known for severe convective thunderstorms. Primarily designed for ultrahigh energy cosmic-ray observations, the Auger FD turns out to be very sensitive to the ultraviolet emission in elves. The detector features modified Schmidt optics with large apertures resulting in a field of view that spans the horizon, and year-round operation on dark nights with low moonlight background, when the local weather is favorable. The measured light profiles of 18% of the elve events have more than one peak, compatible with intracloud activity. Within the 3-year sample, 72% of the elves correlate with the far-field radiation measurements of the World Wide Lightning Location Network. The Auger Observatory plans to continue operations until at least 2025, including elve observations and analysis. To the best of our knowledge, this observatory is the only facility on Earth that measures elves with year-round operation and full horizon coverage., Argentina—Comisión Nacional de Energía Atómica; Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Gobierno de la Provincia de Mendoza; Municipalidad de Malargüe; and NDM Holdings and Valle Las Leñas, in gratitude for their continuing cooperation over land access; Australia—the Australian Research Council; Brazil—Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Financiadora de Estudos e Projetos (FINEP); Fundação de Amparo à Pesquisa do Estado de Rio de Janeiro (FAPERJ); São Paulo Research Foundation (FAPESP) Grants 2010/07359-6 and 1999/05404-3; Ministério da Ciência, Tecnologia, Inovações e Comunicações (MCTIC); Czech Republic—Grants MSMT CRLTT18004, LO1305, LM2015038, and CZ.02.1.01/0.0/0.0/16_013/0001402; France—Centre de Calcul IN2P3/CNRS; Centre National de la Recherche Scientifique (CNRS); Conseil Régional Ile-de-France; Département Physique Nucléaire et Corpusculaire (PNC-IN2P3/CNRS); Département Sciences de l'Univers (SDU-INSU/CNRS); Institut Lagrange de Paris (ILP) Grant LABEX ANR-10-LABX-63 within the Investissements d'Avenir Programme Grant ANR-11-IDEX-0004-02; Germany—Bundesministerium für Bildung und Forschung (BMBF); Deutsche Forschungsgemeinschaft (DFG); Finanzministerium Baden-Württemberg; Helmholtz Alliance for Astroparticle Physics (HAP); Helmholtz-Gemeinschaft. Deutscher Forschungszentren (HGF); Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen; Ministerium für Wissenschaft, Forschung und Kunst des Landes Baden-Württemberg; Italy—Istituto Nazionale di Fisica Nucleare (INFN); Istituto Nazionale di Astrofisica (INAF); Ministero dell'Istruzione, dell'Universitá e della Ricerca (MIUR); CETEMPS Center of Excellence; Ministero degli Affari Esteri (MAE); México—Consejo Nacional de Ciencia y Tecnología (CONACYT)167733; Universidad Nacional Autónoma de México (UNAM); PAPIIT DGAPA-UNAM; The Netherlands—Ministry of Education, Culture and Science; Netherlands Organisation for Scientific Research (NWO); Dutch National e-Infrastructure with the support of SURF Cooperative; Poland—National Centre for Research and Development, Grant ERA-NET-ASPERA/02/11; National Science Centre, Grants 2013/08/M/ST9/00322, 2016/23/B/ST9/01635, and HARMONIA 5–2013/10/M/ST9/00062, UMO-2016/22/M/ST9/00198; Portugal—Portuguese national funds and FEDER funds within Programa Operacional Factores de Competitividade through Fundação para a Ciência e a Tecnologia (COMPETE); Romania—Romanian Ministry of Research and InnovationCNCS/CCCDI-UESFISCDI, projects PN-III-P1-1.2-PCCDI-2017- 0839/19PCCDI/2018, PN-III-P2-2.1-PED-2016-1922, PN-III-P2-2.1-PED-2016-1659, and PN18090102 within PNCDI III; Slovenia—Slovenian Research Agency; Spain—Comunidad de Madrid; Fondo Europeo de Desarrollo Regional (FEDER) funds; Ministerio de Economía y Competitividad; Xunta de Galicia; European Community 7th Framework Program Grant FP7-PEOPLE-2012-IEF-328826; USA—Department of Energy, Contracts DE-AC02-07CH11359, DE-FR02-04ER41300, DE-FG02-99ER41107, and DE-SC0011689; National Science Foundation, Grant 0450696; The Grainger Foundation; Marie Curie-IRSES/EPLANET; European Particle Physics Latin American Network; European Union 7th Framework Program, Grant PIRSES-2009-GA-246806; and UNESCO.

Published
2020

33. Reconstruction of events recorded with the surface detector of the Pierre Auger Observatory

Author

Roberto Mussa, M. I. Micheletti, B. Tome, François Montanet, M. Schimassek, Frank G. Schröder, Peter Hansen, F. Guarino, John Matthews, Ioana Codrina Maris, Peter Buchholz, C. Hojvat, G. C. Hill, Jorge F. Soriano, Vladimir Lenok, Ralph Engel, L. Perrone, Jan Ebr, J. Ridky, Denis Stanca, A. Aab, Brian Fick, Eleonora Guido, Luis Villaseñor, John Farmer, Marco Aglietta, Markus Roth, Lorenzo Caccianiga, Julien Manshanden, Andres Travaini, E. Varela, H. J. Mathes, Maximilian Reininghaus, J.D. Sanabria Gomez, L. Nellen, B. Vargas Cárdenas, Maria-Teresa Dova, Jacco Vink, H.O. Klages, P. Savina, W. Rodrigues de Carvalho, Bjarni Pont, Stanislav Michal, C. Morello, Miroslav Pech, T. Suomijärvi, J. Pallotta, Alena Bakalova, M. Pothast, Pavel Horvath, B. L. Lago, Ralf Ulrich, A. M. Botti, Dusan Mandat, M. L. Díaz Castro, Teresa Bister, Valerio Verzi, M. R. Hampel, Valerio Pirronello, Niraj Dhital, J. Rodriguez Rojo, I. Valiño, Marvin Gottowik, Peter L. Biermann, Jeffrey A. Johnsen, A. A. Nucita, B. Andrada, Fridtjof Feldbusch, L. Calcagni, C. J. Todero Peixoto, Carla Bleve, Rodrigo Guedes Lang, Eric Mayotte, M. Gómez Berisso, G. Farrar, R. C. Shellard, Francesca Zuccarello, K. Choi, Matias Tueros, Sofia Andringa, Paula Gina Isar, F. Riehn, Marina Scornavacche, Paolo Privitera, Kai Daumiller, Günter Sigl, Paul Sommers, A. Blanco, L. Nožka, Enrique Zas, Fernando Contreras, Fred Sarazin, G. De Mauro, Mario Buscemi, Luis A. Anchordoqui, P. Tobiska, A. C. Fauth, Nataliia Borodai, Philipp Papenbreer, Jonathan Biteau, Nicolás González, T. Huege, R.J. Barreira Luz, Petr Travnicek, M. Schimp, F. Sánchez, Antonio Condorelli, Christine Peters, Luis A. Nunez, H. Wilczyński, M. Zavrtanik, P. Stassi, Jörg R. Hörandel, Darko Veberič, R.C. dos Anjos, Radomir Smida, Adriana Vásquez-Ramírez, A. Machado Payeras, Carla Bonifazi, M. Palatka, B. C. Manning, Jose A. Bellido, Isabel Goos, Jeffrey Brack, Olaf Scholten, Trent D. Grubb, Christian Sarmiento-Cano, Humberto Ibarguen Salazar, Fabio Convenga, Martin Vacula, Marcus Niechciol, D. Heck, A.L. Garcia Vegas, R. Squartini, E. De Vito, Giovanni Consolati, M. A. Muller, Alfred Müller, A. Di Matteo, A. Taboada, M. del Río, I. Lhenry-Yvon, Juan Manuel Figueira, Jesús Peña-Rodríguez, Francesco Fenu, B. Wundheiler, A. Puyleart, Corinne Berat, M. Giller, Roberta Colalillo, Fernando Gollan, Maria Rita Coluccia, A. G. Mariazzi, Heino Falcke, A. Fuster, J. Vicha, S. Querchfeld, Gaia Silli, I.D. Vergara Quispe, P.F. Gómez Vitale, D. Nosek, M.P. Panetta, Miguel Mostafa, Petr Schovanek, G. Medina-Tanco, R. Halliday, Charles Timmermans, V. de Souza, Olena Tkachenko, Martina Bohacova, A. Filipčič, F. Salamida, Hernán Asorey, A. Yushkov, G. Matthiae, Antonio Bueno, E. Santos, J. Šupík, Carlo Ventura, Hernan Wahlberg, D. Melo, A. Tapia, Juan Pablo Gongora, G. Torralba Elipe, H. Gemmeke, J. Rautenberg, Gualberto Avila, S. Petrera, Marc Weber, Q. Luce, G. P. Guedes, Toshihiro Fujii, G. Marsella, Dariusz Gora, Ladislav Chytka, Massimo Mastrodicasa, L. Valore, M. Unger, D. Mockler, A. Parra, P. Ruehl, Samo Stanič, A. Weindl, E. M. Santos, Maximilian Stadelmaier, R. Sato, G. Golup, J. F. Valdés Galicia, I. De Mitri, Jakub Juryšek, J. Debatin, A. Bridgeman, Alan Coleman, V. Novotny, J. Hulsman, Rossella Caruso, A. Lucero, Fernando Catalani, David Schmidt, S. Schröder, S. J. Saffi, R. Alves Batista, Bruce R. Dawson, Caterina Trimarelli, Italo Epicoco, Steffen Hahn, P. Ristori, P.O. Mazur, Juan Carlos D'Olivo, T. Pierog, D. Lo Presti, Sullivan Marafico, M. Trini, M. A. Leigui de Oliveira, Xavier Bertou, A. Zepeda, Violet M. Harvey, D. Harari, Esteban Roulet, Pedro Assis, H. Martinez, S. J. De Jong, A. Etchegoyen, Justin M. Albury, Pierre Billoir, F. Pedreira, Marco Giammarchi, Raul Sarmento, Jarryd A. Day, A. Saftoiu, Felix Schlüter, A. Cancio, J. Stasielak, Fabian Gobbi, Piera Luisa Ghia, A.C. Cobos Cerutti, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, Alina Mihaela Badescu, Cristina Galea, Martín Miguel Freire, M. Prouza, J. R. T. de Mello Neto, I. Allekotte, M. J. Roncoroni, L. Bonneau Arbeletche, Denise Boncioli, R. M. de Almeida, Jose Chinellato, Rodrigo Pelayo, Stijn Buitink, Ioana Caracas, A. Letessier-Selvon, Lorenzo Cazon, Alessio Gorgi, Orazio Zapparrata, Carola Dobrigkeit, M. Muzio, A. van Vliet, David Wittkowski, G. Salina, Danielle LaHurd, Olivier Deligny, Tomáš Fodran, R. Lorek, Ugo Giaccari, Alan Watson, M. Perlin, Mihai Niculescu-Oglinzanu, J. Alvarez Castillo, Julian Kemp, R. Conceição, Miroslav Hrabovský, A. Haungs, P. Mantsch, Z. Szadkowski, Alex Kääpä, Octavian Sima, L. Lopes, Jaime Alvarez-Muñiz, H. Schieler, Alexandru Gherghel-Lascu, Q. Dorosti, Lukáš Vaclavek, G. Mancarella, B. Keilhauer, André Schulz, Karl-Heinz Kampert, S. J. Sciutto, Juan Miguel Carceller, Antonella Castellina, D. Nitz, M. Risse, L. R. Wiencke, Jonathan Blazek, C. M. Schäfer, G. Parente, Fabrizia Canfora, L. Zehrer, J. de Oliveira, Alejandro Almela, Thomas Bretz, Corbin Covault, G. Kukec Mezek, Lino Miramonti, M. E. Bertaina, D. de Oliveira Franco, A. Menshikov, P. Abreu, D. Ravignani, Marcel Köpke, M. Platino, Max Malacari, J. Perez Armand, Claudio Galelli, K.-H. Becker, M. Pimenta, P.R. Araújo Ferreira, Tobias Winchen, Florian Lukas Briechle, Silvia Mollerach, B. García, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, R. López, Karen S. Caballero-Mora, Martin Erdmann, J. de Jesús, A. Streich, Gioacchino Alex Anastasi, M. Wirtz, J. Chudoba, Roger W Clay, G. Cataldi, V. Scherini, Serguei Vorobiov, A. Insolia, M. Kleifges, D. Zavrtanik, A.D. Supanitsky, J. Pȩkala, Flavia Gesualdi, Marcos Cerda, M. Urban, W. M. Namasaka, A. C. Rovero, Alexandru Balaceanu, M. Suárez-Durán, Carla Aramo, Vincenzo Rizi, Julien Souchard, D. Martello, M. Ziolkowski, O. Martínez Bravo, K. Mulrey, J. Kleinfeller, Carlos Escobar, Kevin-Druis Merenda, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Castillo, J. A., Alvarez-Muñiz, J., Batista, R. A., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ferreira, P. R. A., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Luz, R. J. B., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Billoir, P., Bister, T., Biteau, J., Blanco, A., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Arbeletche, L. B., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Bridgeman, A., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Calcagni, L., Cancio, A., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., De Almeida, R. M., De Jesus, J., De Jong, S. J., Mauro, G. D., Neto, J. R. T. D. M., Mitri, I. D., De Oliveira, J., Franco, D. D. O., De Souza, V., Vito, E. D., Debatin, J., Rio, M. D., Deligny, O., Dhital, N., Matteo, A. D., Castro, M. L. D., Dobrigkeit, C., D'Olivo, J. C., Dorosti, Q., Anjos, R. C. D., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Vegas, A. L. G., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. G., Vitale, P. F. G., Gongora, J. P., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Halliday, R., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Mezek, G. K., Lago, B. L., Lahurd, D., Lang, R. G., De Oliveira, M. A. L., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Presti, D. L., Lopes, L., Lopez, R., Lorek, R., Luce, Q., Lucero, A., Payeras, A. M., Malacari, M., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Bravo, O. M., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mockler, D., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nuñez, L. A., Palatka, M., Pallotta, J., Panetta, M. P., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pkala, J., Pelayo, R., Peña-Rodriguez, J., Armand, J. P., Perlin, M., Perrone, L., Peters, C., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Ristori, P., Rizi, V., De Carvalho, W. R., Rojo, J. R., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. S., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulz, A., Sciutto, S. J., Scornavacche, M., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Tapia, A., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. T., Tome, B., Elipe, G. T., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Urban, M., Vaclavek, L., Vacula, M., Galicia, J. F. V., Valiño, I., Valore, L., Vliet, A. V., Varela, E., Cardenas, B. V., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Quispe, I. D. V., Verzi, V., Vicha, J., Villaseñor, L., Vink, J., Vorobiov, S., Wahlberg, H., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Ziolkowski, M., Zuccarello, F., Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Pierre Auger, Research unit Astroparticle Physics, Physics, Elementary Particle Physics, Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Castillo J.A., Alvarez-Muñiz J., Batista R.A., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Ferreira P.R.A., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Luz R.J.B., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Billoir P., Bister T., Biteau J., Blanco A., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Arbeletche L.B., Borodai N., Botti A.M., Brack J., Bretz T., Bridgeman A., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Calcagni L., Cancio A., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cerutti A.C.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., De Almeida R.M., De Jesus J., De Jong S.J., Mauro G.D., Neto J.R.T.D.M., Mitri I.D., De Oliveira J., Franco D.D.O., De Souza V., Vito E.D., Debatin J., Rio M.D., Deligny O., Dhital N., Matteo A.D., Castro M.L.D., Dobrigkeit C., D'Olivo J.C., Dorosti Q., Anjos R.C.D., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Vegas A.L.G., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Berisso M.G., Vitale P.F.G., Gongora J.P., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Halliday R., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Mezek G.K., Lago B.L., Lahurd D., Lang R.G., De Oliveira M.A.L., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Presti D.L., Lopes L., Lopez R., Lorek R., Luce Q., Lucero A., Payeras A.M., Malacari M., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Bravo O.M., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mockler D., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nuñez L.A., Palatka M., Pallotta J., Panetta M.P., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pkala J., Pelayo R., Peña-Rodriguez J., Armand J.P., Perlin M., Perrone L., Peters C., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Ristori P., Rizi V., De Carvalho W.R., Rojo J.R., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Gomez J.D.S., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulz A., Sciutto S.J., Scornavacche M., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Timmermans C., Tkachenko O., Tobiska P., Peixoto C.J.T., Tome B., Elipe G.T., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Urban M., Vaclavek L., Vacula M., Galicia J.F.V., Valiño I., Valore L., Vliet A.V., Varela E., Cardenas B.V., Vasquez-Ramirez A., Veberic D., Ventura C., Quispe I.D.V., Verzi V., Vicha J., Villaseñor L., Vink J., Vorobiov S., Wahlberg H., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., Ziolkowski M., Zuccarello F., and High Energy Astrophys. & Astropart. Phys (API, FNWI)

Subjects
Physics::Instrumentation and Detectors, Astronomy, primary [cosmic radiation], 01 natural sciences, 030218 nuclear medicine & medical imaging, Auger, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), 0302 clinical medicine, surface [detector], Observatory, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Data Processing, Large detector systems for particle and astroparticle physics, Large detector-systems performance, Performance of High Energy Physics Detectors, Instrumentation, Mathematical Physics, Largedetector-systems performance, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, astro-ph.HE, Instrumentation et méthodes en physique, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, cascade, observatory, Cascade, ddc:620, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, atmosphere [showers], air, Astrophysics::High Energy Astrophysical Phenomena, water, FOS: Physical sciences, Cosmic ray, Atmosphere, 03 medical and health sciences, Optics, 0103 physical sciences, High Energy Physics, 14. Life underwater, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], ddc:610, Instrumentation and Methods for Astrophysics (astro-ph.IM), Zenith, Engineering & allied operations, Pierre Auger Observatory, showers: atmosphere, 010308 nuclear & particles physics, business.industry, hep-ex, detector: surface, Autres mathématiques, cosmic radiation: primary, Cherenkov counter, Experimental High Energy Physics, Large detector systems for particle and astroparticle physic, High Energy Physics::Experiment, business, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], RAIOS CÓSMICOS, astro-ph.IM
Abstract

Cosmic rays arriving at Earth collide with the upper parts of the atmosphere, thereby inducing extensive air showers. When secondary particles from the cascade arrive at the ground, they are measured by surface detector arrays. We describe the methods applied to the measurements of the surface detector of the Pierre Auger Observatory to reconstruct events with zenith angles less than 60 using the timing and signal information recorded using the water-Cherenkov detector stations. In addition, we assess the accuracy of these methods in reconstructing the arrival directions of the primary cosmic ray particles and the sizes of the induced showers., Argentina - Comisión Nacional de Energía Atómica, Argentina - Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT), Argentina - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina - Gobierno de la Provincia de Mendoza, Argentina - Municipalidad de Malargue, Argentina - NDM Holdings, Argentina - Valle Las Lenas, Australia - Australian Research Council, National Council for Scientific and Technological Development (CNPq), Brazil - Financiadora de Estudos e Projetos (FINEP), Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) 2019/10151-2 2010/07359-6 1999/05404-3, Brazil - Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC), Czech Republic Grant MSMT CR LTT18004 LM2015038 LM2018102 CZ.02.1.01/0.0/0.0/16_013/0001402 CZ.02.1.01/0.0/0.0/18_046/0016010 CZ.02.1.01/0.0/0.0/17_049/0008422, France - Centre de Calcul IN2P3/CNRS, Centre National de la Recherche Scientifique (CNRS), France - Conseil Regional Ile-de-France, France - Departement Physique Nucleaire et Corpusculaire (PNC-IN2P3/CNRS), France - Departement Sciences de l'Univers (SDU-INSU/CNRS), French National Research Agency (ANR) LABEX ANR-10-LABX-63 ANR11-IDEX-0004-02, Federal Ministry of Education & Research (BMBF), German Research Foundation (DFG), Germany - Finanzministerium Baden-Wurttemberg, Germany - Helmholtz Alliance for Astroparticle Physics (HAP), Germany - Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF), Germany - Min-isterium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Germany - Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg, Italy - Istituto Nazionale di Fisica Nucleare (INFN), Italy - Istituto Nazionale di Astrofisica (INAF), Italy - Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), Italy - CETEMPS Center of Excellence, Italy - Ministero degli Affari Esteri (MAE), Consejo Nacional de Ciencia y Tecnología (CONACyT) 167733, México - Universidad Nacional Autónoma de México (UNAM), México - PAPIIT DGAPA-UNAM, The Netherlands - Ministry of Education, Culture and Science, Netherlands Organization for Scientific Research (NWO), The Netherlands - Dutch national e-infrastructure, The Netherlands - SURF Cooperative, Poland - Ministry of Science and Higher Education DIR/WK/2018/11, Poland - National Science Centre 2013/08/M/ST9/00322 2016/23/B/ST9/01635 HARMONIA 52013/10/M/ST9/00062 UMO-2016/22/M/ST9/00198, Portugal - Portuguese national funds, Portugal - FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE), Romania - Romanian Ministry of Education and Research, the Program Nucleu within MCI PN19150201/16N/2019 PN19060102, Romania - Romanian Ministry of Education and Research, the Program Nucleu within PNCDI III PN-III-P11.2-PCCDI-2017-0839/19PCCDI/2018, Slovenian Research Agency - Slovenia P1-0031 P1-0385 I0-0033 N1-0111, Spain - Ministerio de Economía, Industria y Competitividad FPA2017-85114-P FPA2017-85197-P, Spain - Xunta de Galicia ED431C 2017/07, Junta de Andalucía SOMM17/6104/UGR, Spain - Feder Funds, Spain - RENATARedNacional Tematica de Astroparticulas FPA2015-68783-REDT, Spain - Maria de MaeztuUnit of Excellence MDM-2016-0692, United States Department of Energy (DOE) DE-AC02-07CH11359 DE-FR02-04ER41300 DEFG02-99ER41107 DE-SC0011689, National Science Foundation (NSF) 0450696, U.S.A. - Grainger Foundation, U.S.A. - Marie Curie-IRSES/EPLANET, U.S.A. - European Particle Physics Latin American Network, U.S.A. - UNESCO

Published
2020
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34. Pain and Frailty in Hospitalized Older Adults

Author

Ardoino, Ilaria, Franchi, Carlotta, Nobili, Alessandro, Mannucci, Pier Mannuccio, Corli, Oscar, Pier Mannuccio Mannucci, Alessandro, Nobili, Antonello, Pietrangelo, Francesco, Perticone, Giuseppe, Licata, Francesco, Violi, Gino Roberto Corazza, Salvatore, Corrao, Alessandra, Marengoni, Francesco, Salerno, Matteo, Cesari, Mauro, Tettamanti, Luca, Pasina, Carlotta, Franchi, Laura, Cortesi, Gabriella, Miglio, Ilaria, Ardoino, Alessio, Novella, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Irene, Mattioli, Gianni, Biolo, Michela, Zanetti, Giacomo, Bartelloni, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Graziana, Lupattelli, Vanessa, Bianconi, Riccardo, Alcidi, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Vincenza, Beneduce, Federica, Cacioppo, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Marco, Zoli, Maria Laura Matacena, Giuseppe, Orio, Eleonora, Magnolfi, Giovanni, Serafini, Angelo, Simili, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Giovanna, Fabio, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Simona, Leoni, Alessandra Danuta Di Mauro, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Giovanna, Leoncini, Luigi, Anastasio, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Antonella, Giorgi, Christian, Gracin, Giuseppe, Zuccalà, Gabriella, D'Aurizio, Giuseppe, Romanelli, Andrea, Volpini, Daniela, Lucente, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Giuseppe, Bellelli, Maurizio, Corsi, Cesare, Antonucci, Chiara, Sidoli, Giulia, Principato, Franco, Arturi, Elena, Succurro, Bruno, Tassone, Federica, Giofrè, Maria Grazia Serra, Maria Antonietta Bleve, Antonio, Brucato, Teresa De Falco, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Tancredi, Prandini, Roberto, Manfredini, Fabio, Fabbian, Benedetta, Boari, Alfredo De Giorgi, Ruana, Tiseo, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudia, Catalano, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Silvia, Schiavone, Alessio, Bragagni, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Carlo, Custodero, Luigi, Fenoglio, Andrea, Falcetta, Anna, L Fracanzani, Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Giulia, Colombo, Pasquale, Agosti, Valter, Monzani, Valeria, Savojardo, Giuliana, Ceriani, Giada, Pallini, Montecucco, Fabrizio, Luciano, Ottonello, Lara, Caserza, Giulia, Vischi, Nicola Lucio Liberato, Tiziana, Tognin, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Maria Stella Pisciotta, Francesco Baffa Bellucci, Stefano, Buffelli, Giuseppe, Montrucchio, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Carl, Margaria, Maura, Sanino, Ludovica, Perri, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Roberto Davide Diprizio, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Matteo, Galassi, Yasmine, Grassi, Alessio, Greco, Angela, Sciacqua, Maria, Perticone, Rosa, Battaglia, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara Del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Alfio, Gennaro, Agostino, Gaudio, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Carlo, Vigorito, Antonio, Cittadini, Guido, Moreo, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Gonella, Roberta, Domenico, Cerminara, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Leonardo, Sechi, Cristiana, Catena, Gianluca, Colussi, Alessandro, Cavarape, Andea Da Porto, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Margherita, Grossi, Stefano Del Giacco, Davide, Firinu, Giulia, Costanzo, Giacomo, Argiolas, Giuseppe, Montalto, Anna, Licata, Filippo Alessandro Montalto, Francesco, Corica, Giorgio, Basile, Antonino, Catalano, Federica, Bellone, Concetto, Principato, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Giandomenico Nigro Imperiale, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Mattia, Bellan, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Federico, Napoli, Italia, Aiello, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Nome, E Cognome Del Primario, Silvia, Ghidoni, Teresa, Salvatore, Lucio, Monaco, Carmen, Ricozzi, Alberto, Pilotto, Ilaria, Indiano, Federica, Gandolfo, Reposi, Investigator, Ardoino I., Franchi C., Nobili A., Mannucci P.M., Corli O., Pietrangelo A., Perticone F., Licata G., Violi F., Corazza G.R., Corrao S., Marengoni A., Salerno F., Cesari M., Tettamanti M., Pasina L., Cortesi L., Miglio G., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Mattioli I., Biolo G., Zanetti M., Bartelloni G., Vanoli M., Grignani G., Pulixi E.A., Lupattelli G., Bianconi V., Alcidi R., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Beneduce V., Cacioppo F., Natoli G., Mularo S., Raspanti M., Zoli M., Matacena M.L., Orio G., Magnolfi E., Serafini G., Simili A., Palasciano G., Modeo M.E., Di Gennaro C., Cappellini M.D., Fabio G., De Amicis M.M., De Luca G., Scaramellini N., Rossi P.D., Damanti S., Clerici M., Leoni S., Di Mauro A.D., Di Sabatino A., Miceli E., Lenti M.V., Pisati M., Dominioni C.C., Pontremoli R., Beccati V., Nobili G., Leoncini G., Anastasio L., Carbone M., Cipollone F., Guagnano M.T., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Giorgi A., Gracin C., Zuccala G., D'Aurizio G., Romanelli G., Volpini A., Lucente D., Picardi A., Gentilucci U.V., Gallo P., Bellelli G., Corsi M., Antonucci C., Sidoli C., Principato G., Arturi F., Succurro E., Tassone B., Giofre F., Serra M.G., Bleve M.A., Brucato A., De Falco T., Fabris F., Bertozzi I., Bogoni G., Rabuini M.V., Prandini T., Manfredini R., Fabbian F., Boari B., De Giorgi A., Tiseo R., Paolisso G., Rizzo M.R., Catalano C., Borghi C., Strocchi E., Ianniello E., Soldati M., Schiavone S., Bragagni A., Sabba C., Vella F.S., Suppressa P., De Vincenzo G.M., Comitangelo A., Amoruso E., Custodero C., Fenoglio L., Falcetta A., Fracanzani A.L., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Colombo G., Agosti P., Monzani V., Savojardo V., Ceriani G., Pallini G., Montecucco F., Ottonello L., Caserza L., Vischi G., Liberato N.L., Tognin T., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Pisciotta M.S., Bellucci F.B., Buffelli S., Montrucchio G., Peasso P., Favale E., Poletto C., Margaria C., Sanino M., Perri L., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Diprizio R.D., Bertolotti M., Mussi C., Lancellotti G., Libbra M.V., Galassi M., Grassi Y., Greco A., Sciacqua A., Perticone M., Battaglia R., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Mattioli M., Martino G.P., Biondi L., Pettinari P., Ghio R., Col A.D., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M.E., Castellino P., Zanoli L., Gennaro A., Gaudio A., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Vigorito C., Cittadini A., Moreo G., Prolo S., Pina G., Ballestrero A., Ferrando F., Gonella R., Cerminara D., Berra S., Dassi S., Nava M.C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Sechi L., Catena C., Colussi G., Cavarape A., Da Porto A., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G.P., Maggio M.G., Morganti S., Artoni A., Grossi M., Del Giacco S., Firinu D., Costanzo G., Argiolas G., Montalto G., Licata A., Montalto F.A., Corica F., Basile G., Catalano A., Bellone F., Principato C., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., La Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Imperiale G.N., Pirisi M., Fra G.P., Sola D., Bellan M., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Napoli F., Aiello I., Landolfi R., Montalto M., Mirijello A., del Primario N.C., Ghidoni S., Salvatore T., Monaco L., Ricozzi C., Pilotto A., Indiano I., Gandolfo F., Ardoino, Ilaria, Franchi, Carlotta, Nobili, Alessandro, Mannucci, Pier Mannuccio, Corli, Oscar, Borghi C, Stanghellini V, Ardoino, I, Franchi, C, Nobili, A, Mannucci, P, Corli, O, Bellelli, G, Ardoino, I., Franchi, C., Nobili, A., Mannucci, P. M., Corli, O., Pietrangelo, A., Perticone, F., Licata, G., Violi, F., Corazza, G. R., Corrao, S., Marengoni, A., Salerno, F., Cesari, M., Tettamanti, M., Pasina, L., Cortesi, L., Miglio, G., Novella, A., Prisco, D., Silvestri, E., Emmi, G., Bettiol, A., Mattioli, I., Biolo, G., Zanetti, M., Bartelloni, G., Vanoli, M., Grignani, G., Pulixi, E. A., Lupattelli, G., Bianconi, V., Alcidi, R., Girelli, D., Busti, F., Marchi, G., Barbagallo, M., Dominguez, L., Beneduce, V., Cacioppo, F., Natoli, G., Mularo, S., Raspanti, M., Zoli, M., Matacena, M. L., Orio, G., Magnolfi, E., Serafini, G., Simili, A., Palasciano, G., Modeo, M. E., Di Gennaro, C., Cappellini, M. D., Fabio, G., De Amicis, M. M., De Luca, G., Scaramellini, N., Rossi, P. D., Damanti, S., Clerici, M., Leoni, S., Di Mauro, A. D., Di Sabatino, A., Miceli, E., Lenti, M. V., Pisati, M., Dominioni, C. C., Pontremoli, R., Beccati, V., Nobili, G., Leoncini, G., Anastasio, L., Carbone, M., Cipollone, F., Guagnano, M. T., Rossi, I., Mancuso, G., Calipari, D., Bartone, M., Delitala, G., Berria, M., Delitala, A., Muscaritoli, M., Molfino, A., Petrillo, E., Giorgi, A., Gracin, C., Zuccala, G., D'Aurizio, G., Romanelli, G., Volpini, A., Lucente, D., Picardi, A., Gentilucci, U. V., Gallo, P., Bellelli, G., Corsi, M., Antonucci, C., Sidoli, C., Principato, G., Arturi, F., Succurro, E., Tassone, B., Giofre, F., Serra, M. G., Bleve, M. A., Brucato, A., De Falco, T., Fabris, F., Bertozzi, I., Bogoni, G., Rabuini, M. V., Prandini, T., Manfredini, R., Fabbian, F., Boari, B., De Giorgi, A., Tiseo, R., Paolisso, G., Rizzo, M. R., Catalano, C., Borghi, C., Strocchi, E., Ianniello, E., Soldati, M., Schiavone, S., Bragagni, A., Sabba, C., Vella, F. S., Suppressa, P., De Vincenzo, G. M., Comitangelo, A., Amoruso, E., Custodero, C., Fenoglio, L., Falcetta, A., Fracanzani, A. L., Tiraboschi, S., Cespiati, A., Oberti, G., Sigon, G., Peyvandi, F., Rossio, R., Colombo, G., Agosti, P., Monzani, V., Savojardo, V., Ceriani, G., Pallini, G., Montecucco, F., Ottonello, L., Caserza, L., Vischi, G., Liberato, N. L., Tognin, T., Purrello, F., Di Pino, A., Piro, S., Rozzini, R., Falanga, L., Pisciotta, M. S., Bellucci, F. B., Buffelli, S., Montrucchio, G., Peasso, P., Favale, E., Poletto, C., Margaria, C., Sanino, M., Perri, L., Guasti, L., Castiglioni, L., Maresca, A., Squizzato, A., Campiotti, L., Grossi, A., Diprizio, R. D., Bertolotti, M., Mussi, C., Lancellotti, G., Libbra, M. V., Galassi, M., Grassi, Y., Greco, A., Sciacqua, A., Perticone, M., Battaglia, R., Maio, R., Stanghellini, V., Ruggeri, E., del Vecchio, S., Salvi, A., Leonardi, R., Damiani, G., Capeci, W., Mattioli, M., Martino, G. P., Biondi, L., Pettinari, P., Ghio, R., Col, A. D., Minisola, S., Colangelo, L., Cilli, M., Labbadia, G., Afeltra, A., Marigliano, B., Pipita, M. E., Castellino, P., Zanoli, L., Gennaro, A., Gaudio, A., Saracco, V., Fogliati, M., Bussolino, C., Mete, F., Gino, M., Vigorito, C., Cittadini, A., Moreo, G., Prolo, S., Pina, G., Ballestrero, A., Ferrando, F., Gonella, R., Cerminara, D., Berra, S., Dassi, S., Nava, M. C., Graziella, B., Baldassarre, S., Fragapani, S., Gruden, G., Galanti, G., Mascherini, G., Petri, C., Stefani, L., Girino, M., Piccinelli, V., Nasso, F., Gioffre, V., Pasquale, M., Sechi, L., Catena, C., Colussi, G., Cavarape, A., Da Porto, A., Passariello, N., Rinaldi, L., Berti, F., Famularo, G., Tarsitani, P., Castello, R., Pasino, M., Ceda, G. P., Maggio, M. G., Morganti, S., Artoni, A., Grossi, M., Del Giacco, S., Firinu, D., Costanzo, G., Argiolas, G., Montalto, G., Licata, A., Montalto, F. A., Corica, F., Basile, G., Catalano, A., Bellone, F., Principato, C., Malatino, L., Stancanelli, B., Terranova, V., Di Marca, S., Di Quattro, R., La Malfa, L., Caruso, R., Mecocci, P., Ruggiero, C., Boccardi, V., Meschi, T., Ticinesi, A., Nouvenne, A., Minuz, P., Fondrieschi, L., Imperiale, G. N., Pirisi, M., Fra, G. P., Sola, D., Bellan, M., Porta, M., Riva, P., Quadri, R., Larovere, E., Novelli, M., Scanzi, G., Mengoli, C., Provini, S., Ricevuti, L., Simeone, E., Scurti, R., Tolloso, F., Tarquini, R., Valoriani, A., Dolenti, S., Vannini, G., Volpi, R., Bocchi, P., Vignali, A., Harari, S., Lonati, C., Napoli, F., Aiello, I., Landolfi, R., Montalto, M., Mirijello, A., del Primario, N. C., Ghidoni, S., Salvatore, T., Monaco, L., Ricozzi, C., Pilotto, A., Indiano, I., Gandolfo, F., Corli, Oscar, Paolisso, Giuseppe, and Rizzo, Maria Rosaria

Subjects
medicine.medical_specialty, Pain medicine, Socio-culturale, Chronic pain, Osteoarthritis, Affect (psychology), Internal medicine and geriatric wards, Musculoskeletal diseases, Older population, Chronic pain, Internal medicine and geriatric wards, Musculoskeletal diseases, Quality of life, Musculoskeletal disease, Anesthesiology, Internal medicine, medicine, RD78.3-87.3, LS4_4, Original Research, business.industry, medicine.disease, Internal medicine and geriatric ward, Anesthesiology and Pain Medicine, Rheumatoid arthritis, Neurology (clinical), Ordered logit, business
Abstract

Introduction Pain and frailty are prevalent conditions in the older population. Many chronic diseases are likely involved in their origin, and both have a negative impact on quality of life. However, few studies have analysed their association. Methods In light of this knowledge gap, 3577 acutely hospitalized patients 65 years or older enrolled in the REPOSI register, an Italian network of internal medicine and geriatric hospital wards, were assessed to calculate the frailty index (FI). The impact of pain and some of its characteristics on the degree of frailty was evaluated using an ordinal logistic regression model after adjusting for age and gender. Results The prevalence of pain was 24.7%, and among patients with pain, 42.9% was regarded as chronic pain. Chronic pain was associated with severe frailty (OR = 1.69, 95% CI 1.38–2.07). Somatic pain (OR = 1.59, 95% CI 1.23–2.07) and widespread pain (OR = 1.60, 95% CI 0.93–2.78) were associated with frailty. Osteoarthritis was the most common cause of chronic pain, diagnosed in 157 patients (33.5%). Polymyalgia, rheumatoid arthritis and other musculoskeletal diseases causing chronic pain were associated with a lower degree of frailty than osteoarthritis (OR = 0.49, 95%CI 0.28–0.85). Conclusions Chronic and somatic pain negatively affect the degree of frailty. The duration and type of pain, as well as the underlying diseases associated with chronic pain, should be evaluated to improve the hospital management of frail older people. Electronic Supplementary Material The online version of this article (10.1007/s40122-020-00202-3) contains supplementary material, which is available to authorized users.

Published
2020

35. Direct measurement of the muonic content of extensive air showers between $\mathbf { 2\times 10^{17}}$ and $\mathbf {2\times 10^{18}}~$eV at the Pierre Auger Observatory

Author

P. Tobiska, Bjarni Pont, H. J. Mathes, Stanislav Michal, S. Schröder, Italo Epicoco, A. Di Matteo, L. Lopes, B. Wundheiler, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, Lukáš Vaclavek, B. Keilhauer, Ioana Codrina Maris, S. J. Sciutto, J. Rodriguez Rojo, Fridtjof Feldbusch, Alessio Gorgi, D. Melo, G. C. Hill, Juan Miguel Carceller, Jorge F. Soriano, Ralph Engel, Enrique Zas, Orazio Zapparrata, J. Stasielak, L. Calcagni, Kai Daumiller, R. Sato, J. Ridky, Roberto Mussa, Fernando Contreras, Luis Villaseñor, J. Rautenberg, K.-H. Becker, Q. Luce, M. Pimenta, Carola Dobrigkeit, M. Muzio, Maximilian Stadelmaier, Darko Veberič, Maximilian Reininghaus, J. F. Valdés Galicia, I. De Mitri, P.R. Araújo Ferreira, Tobias Winchen, Marvin Gottowik, François Montanet, Alan Watson, M. A. Leigui de Oliveira, M. Perlin, Eric Mayotte, M. Gómez Berisso, Mihai Niculescu-Oglinzanu, J. Alvarez Castillo, Gaia Silli, A. Filipčič, Eleonora Guido, R. C. Shellard, Florian Lukas Briechle, F. Sarazin, T. Huege, Heino Falcke, D. Nitz, A. van Vliet, S. Petrera, L. Nellen, Denise Boncioli, Hernan Wahlberg, P. Abreu, Jeffrey Brack, Olaf Scholten, Mario Buscemi, Marc Weber, Humberto Ibarguen Salazar, R. M. de Almeida, D. Ravignani, J. Vicha, L. R. Wiencke, David Wittkowski, G. Salina, Danielle LaHurd, Olivier Deligny, Lorenzo Caccianiga, C. Morello, Jesús Peña-Rodríguez, E. M. Santos, Dusan Mandat, M. L. Díaz Castro, G. Farrar, R. Squartini, R. Lorek, Ugo Giaccari, Miguel Mostafa, J. Kleinfeller, Bruce R. Dawson, Francesca Zuccarello, B. Tome, P.O. Mazur, Rodrigo Pelayo, K. H. Kampert, Peter L. Biermann, Stijn Buitink, Valerio Verzi, Alfred Müller, A. Aab, Violet M. Harvey, D. Harari, C. M. Schäfer, Jose Chinellato, L. Bonneau Arbeletche, Paolo Privitera, Massimo Mastrodicasa, A. López Casado, Frank G. Schröder, Marcel Köpke, Max Malacari, M. Platino, Samo Stanič, R. Conceição, Miroslav Hrabovský, Julien Manshanden, Ioana Caracas, Kevin-Druis Merenda, A. Letessier-Selvon, Dariusz Gora, Andres Travaini, F. Guarino, John Matthews, Flavia Gesualdi, A. Haungs, J. Perez Armand, Matias Tueros, Alina Mihaela Badescu, Cristina Galea, B. L. Lago, Lorenzo Cazon, E. Varela, Peter Buchholz, J.D. Sanabria Gomez, A. Taboada, M. Prouza, P. Mantsch, G. Matthiae, Z. Szadkowski, A. Parra, R.J. Barreira Luz, Luis A. Nunez, Alan Coleman, Christian Sarmiento-Cano, Marco Aglietta, Marcus Niechciol, S. J. Saffi, G. Medina-Tanco, R. Halliday, P.F. Gómez Vitale, Alena Bakalova, Claudio Galelli, Thomas Hebbeker, Paula Gina Isar, S. Müller, Giovanni Marsella, D. Nosek, E. Santos, F. Riehn, A. Fuster, B. García, Sergio Dasso, Tristan Sudholz, S. Querchfeld, R. López, Karen S. Caballero-Mora, F. Pedreira, Marina Scornavacche, Martín Miguel Freire, Markus Roth, F. Salamida, A. Yushkov, J. Šupík, Carlo Ventura, Raul Sarmento, Jonathan Biteau, Felix Schlüter, Nicolás González, Fabian Gobbi, M. Schimp, G. P. Guedes, Martin Erdmann, Toshihiro Fujii, Ladislav Chytka, G. Cataldi, Antonio Bueno, A. Weindl, P. Ristori, J. de Jesús, B. C. Manning, V. Scherini, Jakub Juryšek, A. Streich, J. Debatin, D. Mockler, David Schmidt, A. Tapia, Gioacchino Alex Anastasi, M. Wirtz, P. Ruehl, Alexandra Saftoiu, A. Puyleart, Corinne Berat, M. Giller, Roger W Clay, G. Kukec Mezek, Steffen Hahn, Juan Carlos D'Olivo, T. Pierog, M. Trini, J. Hulsman, M. E. Bertaina, Esteban Roulet, Justin M. Albury, Francesco Fenu, Valerio Pirronello, H. Gemmeke, A. Menshikov, Denis Stanca, C. J. Todero Peixoto, Piera Luisa Ghia, Miroslav Pech, M. Pothast, Jeffrey A. Johnsen, M. Schimassek, C. Hojvat, Jan Ebr, Pavel Horvath, C. O. Escobar, A. Insolia, H. Wilczyński, Günter Sigl, M. Unger, M. Kleifges, D. Zavrtanik, A.D. Supanitsky, J. Pȩkala, B. Andrada, P. Stassi, A. Cancio, Sofia Andringa, Radomir Smida, A. Machado Payeras, Jacco Vink, V. de Souza, Gualberto Avila, P. Savina, H.O. Klages, M. I. Micheletti, M.P. Panetta, I. Allekotte, M. J. Roncoroni, A. A. Nucita, Ralf Ulrich, B. Vargas Cárdenas, T. Suomijärvi, J. Pallotta, John Farmer, Brian Fick, A. M. Botti, Maria-Teresa Dova, M. R. Hampel, Niraj Dhital, I. Valiño, L. Nožka, Jörg R. Hörandel, R.C. dos Anjos, M. Zavrtanik, Adriana Vásquez-Ramírez, M. Palatka, A. C. Fauth, Giovanni Consolati, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, M. Urban, W. M. Namasaka, A. C. Rovero, Petr Schovanek, Alexandru Balaceanu, M. Suárez-Durán, Carla Aramo, Vincenzo Rizi, I.D. Vergara Quispe, Julien Souchard, D. Martello, M. Ziolkowski, O. Martínez Bravo, Silvia Mollerach, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, J. Chudoba, Serguei Vorobiov, O. A. Taborda, Marcos Cerda, D. Lo Presti, S. J. De Jong, Jarryd A. Day, A.C. Cobos Cerutti, J. R. T. de Mello Neto, W. Rodrigues de Carvalho, Teresa Bister, G. Golup, Nataliia Borodai, K. Choi, Paul Sommers, A. Blanco, F. Sánchez, Antonio Condorelli, Christine Peters, A.L. Garcia Vegas, Luis A. Anchordoqui, Maria Rita Coluccia, Julian Kemp, Philipp Papenbreer, Petr Travnicek, Martina Bohacova, Trent D. Grubb, M. A. Muller, Hernán Asorey, Juan Manuel Figueira, Roberta Colalillo, Giovanni Mancarella, A. G. Mariazzi, Xavier Bertou, A. Zepeda, Juan Pablo Gongora, Pedro Assis, H. Martinez, G. Torralba Elipe, A. Etchegoyen, L. Valore, Alex Kääpä, Patricia María Hansen, Marco Giammarchi, V. Novotny, Octavian Sima, Rossella Caruso, A. Lucero, Fernando Catalani, G. De Mauro, Caterina Trimarelli, H. Schieler, Q. Dorosti, I. Lhenry-Yvon, Antonella Castellina, Vladimir Lenok, L. Perrone, Thomas Bretz, Corbin Covault, Lino Miramonti, D. de Oliveira Franco, Isabel Goos, D. Heck, M. del Río, M. Risse, Jonathan Blazek, Charles Timmermans, G. Parente, Fabrizia Canfora, L. Zehrer, J. de Oliveira, Alejandro Almela, Carla Bleve, Rodrigo Guedes Lang, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and Pierre Auger

Subjects
Physics and Astronomy (miscellaneous), air, Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], Cosmic ray, 01 natural sciences, Auger, detector: fluorescence, Nuclear physics, 5/3, 0103 physical sciences, muon: density, ddc:530, cosmic radiation: UHE, 010306 general physics, Engineering (miscellaneous), Physics, Pierre Auger Observatory, fluorescence [detector], detector [muon], Muon, showers: atmosphere, hybrid, 010308 nuclear & particles physics, muon: detector, Astrophysics::Instrumentation and Methods for Astrophysics, observatory, Air shower, density [muon], 13. Climate action, Content (measure theory), High Energy Physics::Experiment, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Muon detector, atmosphere [showers]
Abstract

The hybrid design of the Pierre Auger Observatory allows for the measurement of the properties of extensive air showers initiated by ultra-high energy cosmic rays with unprecedented precision. By using an array of prototype underground muon detectors, we have performed the first direct measurement, by the Auger Collaboration, of the muon content of air showers between $$2\times 10^{17}$$2×1017 and $$2\times 10^{18}$$2×1018 eV. We have studied the energy evolution of the attenuation-corrected muon density, and compared it to predictions from air shower simulations. The observed densities are found to be larger than those predicted by models. We quantify this discrepancy by combining the measurements from the muon detector with those from the Auger fluorescence detector at $$10^{{17.5}}\, {\mathrm{eV}} $$1017.5eV and $$10^{{18}}\, {\mathrm{eV}} $$1018eV. We find that, for the models to explain the data, an increase in the muon density of $$38\%$$38%$$\pm 4\% (12\%)$$±4%(12%)$$\pm {}^{21\%}_{18\%}$$±18%21% for EPOS-LHC, and of $$50\% (53\%)$$50%(53%)$$\pm 4\% (13\%)$$±4%(13%)$$\pm {}^{23\%}_{20\%}$$±20%23% for QGSJetII-04, is respectively needed.

Published
2020

36. The EUSO@Turlab Project: Tests of Mini-EUSO Engineering Model

Author

A. Franceschi, L. Marcelli, G. Contino, Maria Teresa Ricci, A. Djakonow, Marco Mignone, Lech Wiktor Piotrowski, A. Murashov, J. Szabelski, M.E Bertaina, Naoto Sakaki, Pavel Klimov, W. Marszał, Matteo Battisti, F. Bisconti, Alexander S. Belov, A. Poroshin, K. Shinozaki, S. Blin-Bondil, Daniele Gardiol, Francesca Capel, Francesco Fenu, Enzo Reali, M. Przybylak, A. Cellino, E. Parizot, P. Picozza, M. I. Panasyuk, G. Suino, M. Bertaina, S. Turriziani, Toshikazu Ebisuzaki, Federico Fausti, Marco Casolino, Claudio Fornaro, Guillaume Prévôt, G. Cambiè, I. Churilo, P. Gorodetzky, F. Kajino, M. Traïche, F. Cafagna, Y. Takizawa, Z. Plebaniak, G. Osteria, Christer Fuglesang, R. Bonino, T. Napolitano, Rossella Caruso, G. Cotto, Organisation de Micro-Électronique Générale Avancée (OMEGA), École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), JEM-EUSO, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)

Subjects
Brightness, business.industry, Detector, Cosmic ray, Field of view, Rotating tank, law.invention, Telescope, law, Environmental science, Focal surface, Aerospace engineering, business, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Space debris
Abstract

International audience; The TurLab facility is a laboratory, equipped with a 5 m diameter and 1 m depth rotating tank, located in the Physics Department of the University of Turin. Originally, it was mainly built to study systems of different scales where rotation plays a key role in the fluid behaviour such as in atmospheric and oceanic flows. In the past few years the TurLab facility has been used to perform experiments related to the observation of Extreme Energy Cosmic Rays (EECRs) from space using the fluorescence technique. For example, in the case of the JEM-EUSO mission, where the diffuse night brightness and artificial light sources can vary significantly in time and space inside the Field of View of the telescope. The Focal Surface of Mini-EUSO Engineering Model (Mini-EUSO EM) with the level 1 (L1) and 2 (L2) trigger logics implemented in the Photo-Detector Module (PDM) has been tested at TurLab. Tests related to the possibility of using an EUSO-like detector for other type of applications such as Space Debris (SD) monitoring and imaging detector have also been pursued. The tests and results obtained within the EUSO@TurLab Project on these different topics are presented.

Published
2019

37. Prevalence of use and appropriateness of antidepressants prescription in acutely hospitalized elderly patients

Author

Franchi Carlotta, Rossio Raffaella, Ardoino Ilaria, Nobili Alessandro, Mannucci Pier Mannuccio, Pier Mannuccio Mannucci, Alessandro Nobili, Antonello Pietrangelo, Francesco Perticone, Giuseppe Licata, Francesco Violi, Gino Roberto Corazza, Salvatore Corrao, Alessandra Marengoni, Francesco Salerno, Matteo Cesari, Mauro Tettamanti, Luca Pasina, Carlotta Franchi, Laura Cortesi, Gabriella Miglio, Ilaria Ardoino, Alessio Novella, Domenico Prisco, Elena Silvestri, Giacomo Emmi, Alessandra Bettiol, Cenci Caterina, Gianni Biolo, Michela Zanetti, Martina Guadagni, Michele Zaccari, Massimiliano Chiuch, Massimo Vanoli, Giulia Grignani, Edoardo Alessandro Pulixi, Mauro Bernardi, Silvia Li Bassi, Luca Santi, Giacomo Zaccherini, Graziana Lupattelli, Elmo Mannarino, Vanessa Bianconi, Francesco Paciullo, Riccardo Alcidi, Ranuccio Nuti, Roberto Valenti, Martina Ruvio, Silvia Cappelli, Alberto Palazzuoli, Domenico Girelli, Fabiana Busti, Giacomo Marchi, Mario Barbagallo, Ligia Dominguez, Floriana Cocita, Vincenza Beneduce, Lidia Plances, Giuseppe Natoli, Salvatore Mularo, Massimo Raspanti, Federica Cavallaro, Marco Zoli, Ilaria Lazzari, Mattia Brunori, Elisa Fabbri, Donatella Magalotti, Raffaella Arnò, Franco Laghi Pasini, Pier Leopoldo Capecchi, Giuseppe Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Diletta Maira, Valeria Di Stefano, Giovanna Fabio, Sonia Seghezzi, Marta Mancarella, Margherita Migone De Amicis, Giacomo De Luca, Natalia Scaramellini, Paolo Dionigi Rossi, Sarah Damanti, Marta Clerici, Federica Conti, Giulia Bonini, Barbara Brignolo Ottolini, Antonio Di Sabatino, Emanuela Miceli, Marco Vincenzo Lenti, Martina Pisati, Costanza Caccia Dominioni, Giovanni Murialdo, Alessio Marra, Federico Cattaneo, Roberto Pontremoli, Valentina Beccati, Giulia Nobili, Maria Beatrice Secchi, Davide Ghelfi, Luigi Anastasio, Lucia Sofia, Maria Carbone, Francesco Cipollone, Maria Teresa Guagnano, Emanuele Valeriani, Ilaria Rossi, Gerardo Mancuso, Daniela Calipari, Mosè Bartone, Giuseppe Delitala, Maria Berria, Chiara Pes, Alessandro Delitala, Maurizio Muscaritoli, Alessio Molfino, Enrico Petrillo, Giuseppe Zuccalà, Gabriella D’Aurizio, Giuseppe Romanelli, Alberto Zucchelli, Francesca Manzoni, Andrea Volpini, Antonio Picardi, Umberto Vespasiani Gentilucci, Paolo Gallo, Chiara Dell’Unto, Giorgio Annoni, Maurizio Corsi, Giuseppe Bellelli, Sara Zazzetta, Paolo Mazzola, Hajnalka Szabo, Alessandra Bonfanti, Franco Arturi, Elena Succurro, Mariangela Rubino, Bruno Tassone, Giorgio Sesti, Medicina Interna, Maria Grazia Serra, Maria Antonietta Bleve, Laura Gasbarrone, Maria Rosaria Sajeva, Antonio Brucato, Silvia Ghidoni, Fabrizio Fabris, Irene Bertozzi, Giulia Bogoni, Maria Victoria Rabuini, Elisabetta Cosi, Paolo Scarinzi, Annalisa Amabile, Elisabetta Omenetto, Tancredi Prandini, Roberto Manfredini, Fabio Fabbian, Benedetta Boari, Alfredo De Giorgi, Ruana Tiseo, Roberto De Giorgio, Giuseppe Paolisso, Maria Rosaria Rizzo, Claudio Borghi, Enrico Strocchi, Eugenia Ianniello, Mario Soldati, Carlo Sabbà, Francesco Saverio Vella, Patrizia Suppressa, Andrea Schilardi, Francesca Loparco, Giovanni Michele De Vincenzo, Alessio Comitangelo, Emanuele Amoruso, Luigi Fenoglio, Andrea Falcetta, Christian Bracco, Anna L. Fracanzani, Silvia Fargion, Silvia Tiraboschi, Annalisa Cespiati, Giovanna Oberti, Giordano Sigon, Flora Peyvandi, Raffaella Rossio, Barbara Ferrari, Giulia Colombo, Pasquale Agosti, Valter Monzani, Valeria Savojardo, Christian Folli, Giuliana Ceriani, Giada Pallini, Franco Dallegri, Luciano Ottonello, Luca Liberale, Lara Caserza, Kassem Salam, Nicola Lucio Liberato, Tiziana Tognin, Giovanni Battista Bianchi, Sabrina Giaquinto, Francesco Purrello, Antonino Di Pino, Salvatore Piro, Renzo Rozzini, Lina Falanga, Elena Spazzini, Camillo Ferrandina, Giuseppe Montrucchio, Paolo Petitti, Paolo Peasso, Edoardo Favale, Cesare Poletto, Raffaella Salmi, Piergiorgio Gaudenzi, Ludovica Perri, Raffaele Landolfi, Massimo Montalto, Antonio Mirijello, Luigina Guasti, Luana Castiglioni, Andrea Maresca, Alessandro Squizzato, Leonardo Campiotti, Alessandra Grossi, Marco Bertolotti, Chiara Mussi, Giulia Lancellotti, Maria Vittoria Libbra, Giulia Dondi, Elisa Pellegrini, Lucia Carulli, Matteo Galassi, Yasmine Grassi, Maria Perticone, Rosa Battaglia, Marco FIlice, Raffaele Maio, Vincenzo Stanghellini, Eugenio Ruggeri, Sara del Vecchio, Andrea Salvi, Roberto Leonardi, Giampaolo Damiani, William Capeci, Armando Gabrielli, Massimo Mattioli, Giuseppe Pio Martino, Lorenzo Biondi, Pietro Pettinari, Riccardo Ghio, Anna Dal Col, Salvatore Minisola, Luciano Colangelo, Mirella Cilli, Giancarlo Labbadia, Antonella Afeltra, Benedetta Marigliano, Maria Elena Pipita, Pietro Castellino, Luca Zanoli, Samuele Pignataro, Alfio Gennaro, Julien Blanco, Valter Saracco, Marisa Fogliati, Carlo Bussolino, Francesca Mete, Miriam Gino, Antonio Cittadini, Carlo Vigorito, Michele Arcopinto, Andrea Salzano, Emanuele Bobbio, Alberto Maria Marra, Domenico Sirico, Guido Moreo, Francesca Gasparini, Silvia Prolo, Gloria Pina, Alberto Ballestrero, Fabio Ferrando, Sergio Berra, Simonetta Dassi, Maria Cristina Nava, Bruno Graziella, Stefano Baldassarre, Salvatore Fragapani, Gabriella Gruden, Giorgio Galanti, Gabriele Mascherini, Cristian Petri, Laura Stefani, Margherita Girino, Valeria Piccinelli, Francesco Nasso, Vincenza Gioffrè, Maria Pasquale, Giuseppe Scattolin, Sergio Martinelli, Mauro Turrin, Leonardo Sechi, Cristina Catena, Gianluca Colussi, Nicola Passariello, Luca Rinaldi, Franco Berti, Giuseppe Famularo, Patrizia Tarsitani, Roberto Castello, Michela Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta Morganti, Andrea Artoni, Stefano Del Giacco, Davide Firinu, Francesca Losa, Giovanni Paoletti, Giulia Costanzo, Giuseppe Montalto, Anna Licata, Valentina Malerba, Filippo Alessandro Montalto, Antonino Lasco, Giorgio Basile, Antonino Catalano, Lorenzo Malatino, Benedetta Stancanelli, Valentina Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella Caruso, Patrizia Mecocci, Carmelinda Ruggiero, Virginia Boccardi, Tiziana Meschi, Fulvio Lauretani, Andrea Ticinesi, Antonio Nouvenne, Pietro Minuz, Luigi Fondrieschi, Mario Pirisi, Gian Paolo Fra, Daniele Sola, Massimo Porta, Piero Riva, Roberto Quadri, Erica Larovere, Marco Novelli, Giorgio Scanzi, Caterina Mengoli, Stella Provini, Laura Ricevuti, Emilio Simeone, Rosa Scurti, Fabio Tolloso, Roberto Tarquini, Alice Valoriani, Silvia Dolenti, Giulia Vannini, Alberto Tedeschi, Lucia Trotta, Riccardo Volpi, Pietro Bocchi, Alessandro Vignali, Sergio Harari, Chiara Lonati, Mara Cattaneo, Federico Napoli, Carlotta, F., Raffaella, R., Ilaria, A., Alessandro, N., Mannuccio, M. P., Mannucci, P. M., Nobili, A., Pietrangelo, A., Perticone, F., Licata, G., Violi, F., Corazza, G. R., Corrao, S., Marengoni, A., Salerno, F., Cesari, M., Tettamanti, M., Pasina, L., Franchi, C., Cortesi, L., Miglio, G., Ardoino, I., Novella, A., Prisco, D., Silvestri, E., Emmi, G., Bettiol, A., Caterina, C., Biolo, G., Zanetti, M., Guadagni, M., Zaccari, M., Chiuch, M., Vanoli, M., Grignani, G., Pulixi, E. A., Bernardi, M., Bassi, S. L., Santi, L., Zaccherini, G., Lupattelli, G., Mannarino, E., Bianconi, V., Paciullo, F., Alcidi, R., Nuti, R., Valenti, R., Ruvio, M., Cappelli, S., Palazzuoli, A., Girelli, D., Busti, F., Marchi, G., Barbagallo, M., Dominguez, L., Cocita, F., Beneduce, V., Plances, L., Natoli, G., Mularo, S., Raspanti, M., Cavallaro, F., Zoli, M., Lazzari, I., Brunori, M., Fabbri, E., Magalotti, D., Arno, R., Pasini, F. L., Capecchi, P. L., Palasciano, G., Modeo, M. E., Gennaro, C. D., Cappellini, M. D., Maira, D., Di Stefano, V., Fabio, G., Seghezzi, S., Mancarella, M., De Amicis, M. M., De Luca, G., Scaramellini, N., Rossi, P. D., Damanti, S., Clerici, M., Conti, F., Bonini, G., Ottolini, B. B., Di Sabatino, A., Miceli, E., Lenti, M. V., Pisati, M., Dominioni, C. C., Murialdo, G., Marra, A., Cattaneo, F., Pontremoli, R., Beccati, V., Nobili, G., Secchi, M. B., Ghelfi, D., Anastasio, L., Sofia, L., Carbone, M., Cipollone, F., Guagnano, M. T., Valeriani, E., Rossi, I., Mancuso, G., Calipari, D., Bartone, M., Delitala, G., Berria, M., Pes, C., Delitala, A., Muscaritoli, M., Molfino, A., Petrillo, E., Zuccala, G., D'Aurizio, G., Romanelli, G., Zucchelli, A., Manzoni, F., Volpini, A., Picardi, A., Gentilucci, U. V., Gallo, P., Dell'Unto, C., Annoni, G., Corsi, M., Bellelli, G., Zazzetta, S., Mazzola, P., Szabo, H., Bonfanti, A., Arturi, F., Succurro, E., Rubino, M., Tassone, B., Sesti, G., Interna, M., Serra, M. G., Bleve, M. A., Gasbarrone, L., Sajeva, M. R., Brucato, A., Ghidoni, S., Fabris, F., Bertozzi, I., Bogoni, G., Rabuini, M. V., Cosi, E., Scarinzi, P., Amabile, A., Omenetto, E., Prandini, T., Manfredini, R., Fabbian, F., Boari, B., Giorgi, A. D., Tiseo, R., De Giorgio, R., Paolisso, G., Rizzo, M. R., Borghi, C., Strocchi, E., Ianniello, E., Soldati, M., Sabba, C., Vella, F. S., Suppressa, P., Schilardi, A., Loparco, F., De Vincenzo, G. M., Comitangelo, A., Amoruso, E., Fenoglio, L., Falcetta, A., Bracco, C., Fracanzani, A. L., Fargion, S., Tiraboschi, S., Cespiati, A., Oberti, G., Sigon, G., Peyvandi, F., Rossio, R., Ferrari, B., Colombo, G., Agosti, P., Monzani, V., Savojardo, V., Folli, C., Ceriani, G., Pallini, G., Dallegri, F., Ottonello, L., Liberale, L., Caserza, L., Salam, K., Liberato, N. L., Tognin, T., Bianchi, G. B., Giaquinto, S., Purrello, F., Di Pino, A., Piro, S., Rozzini, R., Falanga, L., Spazzini, E., Ferrandina, C., Montrucchio, G., Petitti, P., Peasso, P., Favale, E., Poletto, C., Salmi, R., Gaudenzi, P., Perri, L., Landolfi, R., Montalto, M., Mirijello, A., Guasti, L., Castiglioni, L., Maresca, A., Squizzato, A., Campiotti, L., Grossi, A., Bertolotti, M., Mussi, C., Lancellotti, G., Libbra, M. V., Dondi, G., Pellegrini, E., Carulli, L., Galassi, M., Grassi, Y., Perticone, M., Battaglia, R., Filice, M., Maio, R., Stanghellini, V., Ruggeri, E., del Vecchio, S., Salvi, A., Leonardi, R., Damiani, G., Capeci, W., Gabrielli, A., Mattioli, M., Martino, G. P., Biondi, L., Pettinari, P., Ghio, R., Col, A. D., Minisola, S., Colangelo, L., Cilli, M., Labbadia, G., Afeltra, A., Marigliano, B., Pipita, M. E., Castellino, P., Zanoli, L., Pignataro, S., Gennaro, A., Blanco, J., Saracco, V., Fogliati, M., Bussolino, C., Mete, F., Gino, M., Cittadini, A., Vigorito, C., Arcopinto, M., Salzano, A., Bobbio, E., Marra, A. M., Sirico, D., Moreo, G., Gasparini, F., Prolo, S., Pina, G., Ballestrero, A., Ferrando, F., Berra, S., Dassi, S., Nava, M. C., Graziella, B., Baldassarre, S., Fragapani, S., Gruden, G., Galanti, G., Mascherini, G., Petri, C., Stefani, L., Girino, M., Piccinelli, V., Nasso, F., Gioffre, V., Pasquale, M., Scattolin, G., Martinelli, S., Turrin, M., Sechi, L., Catena, C., Colussi, G., Passariello, N., Rinaldi, L., Berti, F., Famularo, G., Tarsitani, P., Castello, R., Pasino, M., Ceda, G. P., Maggio, M. G., Morganti, S., Artoni, A., Del Giacco, S., Firinu, D., Losa, F., Paoletti, G., Costanzo, G., Montalto, G., Licata, A., Malerba, V., Montalto, F. A., Lasco, A., Basile, G., Catalano, A., Malatino, L., Stancanelli, B., Terranova, V., Di Marca, S., Di Quattro, R., La Malfa, L., Caruso, R., Mecocci, P., Ruggiero, C., Boccardi, V., Meschi, T., Lauretani, F., Ticinesi, A., Nouvenne, A., Minuz, P., Fondrieschi, L., Pirisi, M., Fra, G. P., Sola, D., Porta, M., Riva, P., Quadri, R., Larovere, E., Novelli, M., Scanzi, G., Mengoli, C., Provini, S., Ricevuti, L., Simeone, E., Scurti, R., Tolloso, F., Tarquini, R., Valoriani, A., Dolenti, S., Vannini, G., Tedeschi, A., Trotta, L., Volpi, R., Bocchi, P., Vignali, A., Harari, S., Lonati, C., Cattaneo, M., Napoli, F., Carlotta F., Raffaella R., Ilaria A., Alessandro N., Mannuccio M.P., Mannucci P.M., Nobili A., Pietrangelo A., Perticone F., Licata G., Violi F., Corazza G.R., Corrao S., Marengoni A., Salerno F., Cesari M., Tettamanti M., Pasina L., Franchi C., Cortesi L., Miglio G., Ardoino I., Novella A., Prisco D., Silvestri E., Emmi G., Bettiol A., Caterina C., Biolo G., Zanetti M., Guadagni M., Zaccari M., Chiuch M., Vanoli M., Grignani G., Pulixi E.A., Bernardi M., Bassi S.L., Santi L., Zaccherini G., Lupattelli G., Mannarino E., Bianconi V., Paciullo F., Alcidi R., Nuti R., Valenti R., Ruvio M., Cappelli S., Palazzuoli A., Girelli D., Busti F., Marchi G., Barbagallo M., Dominguez L., Cocita F., Beneduce V., Plances L., Natoli G., Mularo S., Raspanti M., Cavallaro F., Zoli M., Lazzari I., Brunori M., Fabbri E., Magalotti D., Arno R., Pasini F.L., Capecchi P.L., Palasciano G., Modeo M.E., Gennaro C.D., Cappellini M.D., Maira D., Di Stefano V., Fabio G., Seghezzi S., Mancarella M., De Amicis M.M., De Luca G., Scaramellini N., Rossi P.D., Damanti S., Clerici M., Conti F., Bonini G., Ottolini B.B., Di Sabatino A., Miceli E., Lenti M.V., Pisati M., Dominioni C.C., Murialdo G., Marra A., Cattaneo F., Pontremoli R., Beccati V., Nobili G., Secchi M.B., Ghelfi D., Anastasio L., Sofia L., Carbone M., Cipollone F., Guagnano M.T., Valeriani E., Rossi I., Mancuso G., Calipari D., Bartone M., Delitala G., Berria M., Pes C., Delitala A., Muscaritoli M., Molfino A., Petrillo E., Zuccala G., D'Aurizio G., Romanelli G., Zucchelli A., Manzoni F., Volpini A., Picardi A., Gentilucci U.V., Gallo P., Dell'Unto C., Annoni G., Corsi M., Bellelli G., Zazzetta S., Mazzola P., Szabo H., Bonfanti A., Arturi F., Succurro E., Rubino M., Tassone B., Sesti G., Interna M., Serra M.G., Bleve M.A., Gasbarrone L., Sajeva M.R., Brucato A., Ghidoni S., Fabris F., Bertozzi I., Bogoni G., Rabuini M.V., Cosi E., Scarinzi P., Amabile A., Omenetto E., Prandini T., Manfredini R., Fabbian F., Boari B., Giorgi A.D., Tiseo R., De Giorgio R., Paolisso G., Rizzo M.R., Borghi C., Strocchi E., Ianniello E., Soldati M., Sabba C., Vella F.S., Suppressa P., Schilardi A., Loparco F., De Vincenzo G.M., Comitangelo A., Amoruso E., Fenoglio L., Falcetta A., Bracco C., Fracanzani A.L., Fargion S., Tiraboschi S., Cespiati A., Oberti G., Sigon G., Peyvandi F., Rossio R., Ferrari B., Colombo G., Agosti P., Monzani V., Savojardo V., Folli C., Ceriani G., Pallini G., Dallegri F., Ottonello L., Liberale L., Caserza L., Salam K., Liberato N.L., Tognin T., Bianchi G.B., Giaquinto S., Purrello F., Di Pino A., Piro S., Rozzini R., Falanga L., Spazzini E., Ferrandina C., Montrucchio G., Petitti P., Peasso P., Favale E., Poletto C., Salmi R., Gaudenzi P., Perri L., Landolfi R., Montalto M., Mirijello A., Guasti L., Castiglioni L., Maresca A., Squizzato A., Campiotti L., Grossi A., Bertolotti M., Mussi C., Lancellotti G., Libbra M.V., Dondi G., Pellegrini E., Carulli L., Galassi M., Grassi Y., Perticone M., Battaglia R., FIlice M., Maio R., Stanghellini V., Ruggeri E., del Vecchio S., Salvi A., Leonardi R., Damiani G., Capeci W., Gabrielli A., Mattioli M., Martino G.P., Biondi L., Pettinari P., Ghio R., Col A.D., Minisola S., Colangelo L., Cilli M., Labbadia G., Afeltra A., Marigliano B., Pipita M.E., Castellino P., Zanoli L., Pignataro S., Gennaro A., Blanco J., Saracco V., Fogliati M., Bussolino C., Mete F., Gino M., Cittadini A., Vigorito C., Arcopinto M., Salzano A., Bobbio E., Marra A.M., Sirico D., Moreo G., Gasparini F., Prolo S., Pina G., Ballestrero A., Ferrando F., Berra S., Dassi S., Nava M.C., Graziella B., Baldassarre S., Fragapani S., Gruden G., Galanti G., Mascherini G., Petri C., Stefani L., Girino M., Piccinelli V., Nasso F., Gioffre V., Pasquale M., Scattolin G., Martinelli S., Turrin M., Sechi L., Catena C., Colussi G., Passariello N., Rinaldi L., Berti F., Famularo G., Tarsitani P., Castello R., Pasino M., Ceda G.P., Maggio M.G., Morganti S., Artoni A., Del Giacco S., Firinu D., Losa F., Paoletti G., Costanzo G., Montalto G., Licata A., Malerba V., Montalto F.A., Lasco A., Basile G., Catalano A., Malatino L., Stancanelli B., Terranova V., Di Marca S., Di Quattro R., La Malfa L., Caruso R., Mecocci P., Ruggiero C., Boccardi V., Meschi T., Lauretani F., Ticinesi A., Nouvenne A., Minuz P., Fondrieschi L., Pirisi M., Fra G.P., Sola D., Porta M., Riva P., Quadri R., Larovere E., Novelli M., Scanzi G., Mengoli C., Provini S., Ricevuti L., Simeone E., Scurti R., Tolloso F., Tarquini R., Valoriani A., Dolenti S., Vannini G., Tedeschi A., Trotta L., Volpi R., Bocchi P., Vignali A., Harari S., Lonati C., Cattaneo M., Napoli F., Carlotta, F, Raffaella, R, Ilaria, A, Alessandro, N, Mannuccio, M, Mannucci, P, Nobili, A, Pietrangelo, A, Perticone, F, Licata, G, Violi, F, Corazza, G, Corrao, S, Marengoni, A, Salerno, F, Cesari, M, Tettamanti, M, Pasina, L, Franchi, C, Cortesi, L, Miglio, G, Ardoino, I, Novella, A, Prisco, D, Silvestri, E, Emmi, G, Bettiol, A, Caterina, C, Biolo, G, Zanetti, M, Guadagni, M, Zaccari, M, Chiuch, M, Vanoli, M, Grignani, G, Pulixi, E, Bernardi, M, Bassi, S, Santi, L, Zaccherini, G, Lupattelli, G, Mannarino, E, Bianconi, V, Paciullo, F, Alcidi, R, Nuti, R, Valenti, R, Ruvio, M, Cappelli, S, Palazzuoli, A, Girelli, D, Busti, F, Marchi, G, Barbagallo, M, Dominguez, L, Cocita, F, Beneduce, V, Plances, L, Natoli, G, Mularo, S, Raspanti, M, Cavallaro, F, Zoli, M, Lazzari, I, Brunori, M, Fabbri, E, Magalotti, D, Arno, R, Pasini, F, Capecchi, P, Palasciano, G, Modeo, M, Gennaro, C, Cappellini, M, Maira, D, Di Stefano, V, Fabio, G, Seghezzi, S, Mancarella, M, De Amicis, M, De Luca, G, Scaramellini, N, Rossi, P, Damanti, S, Clerici, M, Conti, F, Bonini, G, Ottolini, B, Di Sabatino, A, Miceli, E, Lenti, M, Pisati, M, Dominioni, C, Murialdo, G, Marra, A, Cattaneo, F, Pontremoli, R, Beccati, V, Nobili, G, Secchi, M, Ghelfi, D, Anastasio, L, Sofia, L, Carbone, M, Cipollone, F, Guagnano, M, Valeriani, E, Rossi, I, Mancuso, G, Calipari, D, Bartone, M, Delitala, G, Berria, M, Pes, C, Delitala, A, Muscaritoli, M, Molfino, A, Petrillo, E, Zuccala, G, D'Aurizio, G, Romanelli, G, Zucchelli, A, Manzoni, F, Volpini, A, Picardi, A, Gentilucci, U, Gallo, P, Dell'Unto, C, Annoni, G, Corsi, M, Bellelli, G, Zazzetta, S, Mazzola, P, Szabo, H, Bonfanti, A, Arturi, F, Succurro, E, Rubino, M, Tassone, B, Sesti, G, Interna, M, Serra, M, Bleve, M, Gasbarrone, L, Sajeva, M, Brucato, A, Ghidoni, S, Fabris, F, Bertozzi, I, Bogoni, G, Rabuini, M, Cosi, E, Scarinzi, P, Amabile, A, Omenetto, E, Prandini, T, Manfredini, R, Fabbian, F, Boari, B, Giorgi, A, Tiseo, R, De Giorgio, R, Paolisso, G, Rizzo, M, Borghi, C, Strocchi, E, Ianniello, E, Soldati, M, Sabba, C, Vella, F, Suppressa, P, Schilardi, A, Loparco, F, De Vincenzo, G, Comitangelo, A, Amoruso, E, Fenoglio, L, Falcetta, A, Bracco, C, Fracanzani, A, Fargion, S, Tiraboschi, S, Cespiati, A, Oberti, G, Sigon, G, Peyvandi, F, Rossio, R, Ferrari, B, Colombo, G, Agosti, P, Monzani, V, Savojardo, V, Folli, C, Ceriani, G, Pallini, G, Dallegri, F, Ottonello, L, Liberale, L, Caserza, L, Salam, K, Liberato, N, Tognin, T, Bianchi, G, Giaquinto, S, Purrello, F, Di Pino, A, Piro, S, Rozzini, R, Falanga, L, Spazzini, E, Ferrandina, C, Montrucchio, G, Petitti, P, Peasso, P, Favale, E, Poletto, C, Salmi, R, Gaudenzi, P, Perri, L, Landolfi, R, Montalto, M, Mirijello, A, Guasti, L, Castiglioni, L, Maresca, A, Squizzato, A, Campiotti, L, Grossi, A, Bertolotti, M, Mussi, C, Lancellotti, G, Libbra, M, Dondi, G, Pellegrini, E, Carulli, L, Galassi, M, Grassi, Y, Perticone, M, Battaglia, R, Filice, M, Maio, R, Stanghellini, V, Ruggeri, E, del Vecchio, S, Salvi, A, Leonardi, R, Damiani, G, Capeci, W, Gabrielli, A, Mattioli, M, Martino, G, Biondi, L, Pettinari, P, Ghio, R, Col, A, Minisola, S, Colangelo, L, Cilli, M, Labbadia, G, Afeltra, A, Marigliano, B, Pipita, M, Castellino, P, Zanoli, L, Pignataro, S, Gennaro, A, Blanco, J, Saracco, V, Fogliati, M, Bussolino, C, Mete, F, Gino, M, Cittadini, A, Vigorito, C, Arcopinto, M, Salzano, A, Bobbio, E, Sirico, D, Moreo, G, Gasparini, F, Prolo, S, Pina, G, Ballestrero, A, Ferrando, F, Berra, S, Dassi, S, Nava, M, Graziella, B, Baldassarre, S, Fragapani, S, Gruden, G, Galanti, G, Mascherini, G, Petri, C, Stefani, L, Girino, M, Piccinelli, V, Nasso, F, Gioffre, V, Pasquale, M, Scattolin, G, Martinelli, S, Turrin, M, Sechi, L, Catena, C, Colussi, G, Passariello, N, Rinaldi, L, Berti, F, Famularo, G, Tarsitani, P, Castello, R, Pasino, M, Ceda, G, Maggio, M, Morganti, S, Artoni, A, Del Giacco, S, Firinu, D, Losa, F, Paoletti, G, Costanzo, G, Montalto, G, Licata, A, Malerba, V, Montalto, F, Lasco, A, Basile, G, Catalano, A, Malatino, L, Stancanelli, B, Terranova, V, Di Marca, S, Di Quattro, R, La Malfa, L, Caruso, R, Mecocci, P, Ruggiero, C, Boccardi, V, Meschi, T, Lauretani, F, Ticinesi, A, Nouvenne, A, Minuz, P, Fondrieschi, L, Pirisi, M, Fra, G, Sola, D, Porta, M, Riva, P, Quadri, R, Larovere, E, Novelli, M, Scanzi, G, Mengoli, C, Provini, S, Ricevuti, L, Simeone, E, Scurti, R, Tolloso, F, Tarquini, R, Valoriani, A, Dolenti, S, Vannini, G, Tedeschi, A, Trotta, L, Volpi, R, Bocchi, P, Vignali, A, Harari, S, Lonati, C, Cattaneo, M, and Napoli, F

Subjects
Male, medicine.medical_specialty, Socio-culturale, Inappropriate Prescribing, Potentially inappropriate medication, older, Practice Patterns, depression, hospitalized patients, drugs, elderly, drugs, antidepressivi anziano, Polypharmacy | Inappropriate Prescribing | Medications PIMs, antidepressant agent, escitalopram, paroxetine, Internal Medicine, medicine, Hospital discharge, older, Escitalopram, Humans, LS4_4, Medical prescription, Practice Patterns, Physicians', Depression (differential diagnoses), Aged, Polypharmacy, Sertraline, Physicians', antidepressant, business.industry, Trazodone, hospitalized patients, Antidepressive Agents, Hospitalization, Acute Disease, Female, Italy, antidepressants, Emergency medicine, depression, Polypharmacy , Inappropriate Prescribing , Medications, PIM, Delirium, Potentially inappropriate medication, medicine.symptom, business, medicine.drug
Abstract

Depression is often under-recognized in older patients, even if antidepressants (AD) are commonly prescribed, with a prevalence of use that increase with ageing [ 1 ]. Nevertheless, even if a diagnosis of depression is established, inappropriate treatment can occur [ 2 ]. Beers criteria are the most widely screening tools used to detect inappropriate prescription of drugs in people aged 65 years or more [ 3 ]. Since 2010, attempts to adapt the Beers' criteria have been made in Europe [ 4 , 5 ]. Tricyclic drugs are the ADs to be always avoided in the elderly, owing to their anticholinergic side effects, such as cognitive impairment, delirium, urinary retention and falls [ 3 ]. Selective serotonin reuptake inhibitors (SSRIs) should be used with caution because they can cause or exacerbate hyponatraemia [ 3 ]. To our knowledge no studies have been conducted on recent data collected in hospitalized older patients in order to assess the appropriateness of prescription of ADs. With this background, the objectives of this study were to investigate the prevalence of AD use and prescription appropriateness, according to the above-cited criteria, in a large cohort of older patients hospitalized in Italian internal medicine and geriatric wards from 2010 to 2017.

Published
2019

38. Use and prescription appropriateness of drugs for peptic ulcer and gastrooesophageal reflux disease in hospitalized older people

Author

Carlotta, Franchi, Pier Mannuccio Mannucci, Alessandro, Nobili, Ilaria, Ardoino, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Cenci, Caterina, Gianni, Biolo, Michela, Zanetti, Martina, Guadagni, Michele, Zaccari, Massimiliano, Chiuch, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Mauro, Bernardi, Silvia Li Bassi, Luca, Santi, Giacomo, Zaccherini, Graziana, Lupattelli, Elmo, Mannarino, Vanessa, Bianconi, Francesco, Paciullo, Riccardo, Alcidi, Ranuccio, Nuti, Roberto, Valenti, Martina, Ruvio, Silvia, Cappelli, Alberto, Palazzuoli, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Floriana, Cocita, Vincenza, Beneduce, Lidia, Plances, Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Federica, Cavallaro, Marco, Zoli, Ilaria, Lazzari, Mattia, Brunori, Elisa, Fabbri, Donatella, Magalotti, Raffaella, Arnò, Franco Laghi Pasini, Pier Leopoldo Capecchi, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Diletta, Maira, Valeria Di Stefano, Giovanna, Fabio, Sonia, Seghezzi, Marta, Mancarella, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Matteo, Cesari, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Federica, Conti, Giulia, Bonini, Barbara Brignolo Ottolini, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Giovanni, Murialdo, Alessio, Marra, Federico, Cattaneo, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Maria Beatrice Secchi, Davide, Ghelfi, Luigi, Anastasio, Lucia, Sofia, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Emanuele, Valeriani, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Chiara, Pes, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Alessandra, Marengoni, Alberto, Zucchelli, Francesca, Manzoni, Andrea, Volpini, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Chiara, Dell’Unto, Giorgio, Annoni, Maurizio, Corsi, Giuseppe, Bellelli, Sara, Zazzetta, Paolo, Mazzola, Hajnalka, Szabo, Alessandra, Bonfanti, Franco, Arturi, Elena, Succurro, Mariangela, Rubino, Bruno, Tassone, Giorgio, Sesti, Maria Grazia Serra, Maria Antonietta Bleve, Laura, Gasbarrone, Maria Rosaria Sajeva, Antonio, Brucato, Silvia, Ghidoni, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Elisabetta, Cosi, Paolo, Scarinzi, Annalisa, Amabile, Elisabetta, Omenetto, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, Alfredo De Giorgi, Ruana, Tiseo, DE GIORGIO, Roberto, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Pasquale, Agosti, Andrea, Schilardi, Francesca, Loparco, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Luigi, Fenoglio, Andrea, Falcetta, Christian, Bracco, Fracanzani Silvia Fargion, Anna L., Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Raffaella, Rossio, Barbara, Ferrari, Giulia, Colombo, Valter, Monzani, Valeria, Savojardo, Christian, Folli, Giuliana, Ceriani, Francesco, Salerno, Giada, Pallini, Franco, Dallegri, Luciano, Ottonello, Luca, Liberale, Lara, Caserza, Kassem, Salam, Nicola Lucio Liberato, Tiziana, Tognin, Giovanni Battista Bianchi, Sabrina, Giaquinto, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Elena, Spazzini, Camillo, Ferrandina, Giuseppe, Montrucchio, Paolo, Petitti, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Raffaella, Salmi, Piergiorgio, Gaudenzi, Francesco, Violi, Ludovica, Perri, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Giulia, Dondi, Elisa, Pellegrini, Lucia, Carulli, Matteo, Galassi, Yasmine, Grassi, Francesco, Perticone, Maria, Perticone, Rosa, Battaglia, Marco, Filice, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Armando, Gabrielli, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Samuele, Pignataro, Alfio, Gennaro, Julien, Blanco, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Antonio, Cittadini, Carlo, Vigorito, Michele, Arcopinto, Andrea, Salzano, Emanuele, Bobbio, Alberto Maria Marra, Domenico, Sirico, Guido, Moreo, Francesca, Gasparini, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Giuseppe, Scattolin, Sergio, Martinelli, Mauro, Turrin, Leonardo, Sechi, Cristina, Catena, Gianluca, Colussi, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Stefano Del Giacco, Davide, Firinu, Francesca, Losa, Giovanni, Paoletti, Giulia, Costanzo, Giuseppe, Montalto, Anna, Licata, Valentina, Malerba, Filippo Alessandro Montalto, Antonino, Lasco, Giorgio, Basile, Antonino, Catalano, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Fulvio, Lauretani, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Alberto, Tedeschi, Lucia, Trotta, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Mara, Cattaneo, and Federico, Napoli.

Subjects
Drug, Male, medicine.medical_specialty, Peptic Ulcer, Appropriateness, Drug prescription, Hospital setting, Older people, Proton pump inhibitors, Prescription Drugs, Proton pump inhibitors, media_common.quotation_subject, Drug prescription, Socio-culturale, Context (language use), Inappropriate Prescribing, 030226 pharmacology & pharmacy, Drug Prescriptions, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Gastrooesophageal reflux disease, medicine, Prevalence, LS7_3, Humans, Pharmacology (medical), Appropriateness, 030212 general & internal medicine, Medical prescription, Reimbursement, media_common, Aged, Pharmacology, biology, business.industry, General Medicine, Helicobacter pylori, biology.organism_classification, medicine.disease, digestive system diseases, Drug Utilization, Patient Discharge, Hospitalization, Cross-Sectional Studies, Italy, Peptic ulcer, GERD, Gastroesophageal Reflux, Female, Hospital setting, Older people, business
Abstract

The aims of this study were to assess the prevalence of use and prescription appropriateness of drugs for peptic ulcer and gastrooesophageal reflux disease (GERD) at hospital admission and discharge. Patients aged 65 years or more hospitalized from 2010 to 2016 in 101 Italian internal medicine and geriatric wards in the context of the REPOSI register were scrutinized to assess if they were prescribed with drugs for peptic ulcer and GERD at hospital admission and discharge. Appropriateness of prescription was assessed considering the presence of specific conditions (i.e., history of peptic ulcer or gastrointestinal hemorrhages, advanced age, Helicobacter Pylori) or gastro-toxic drug combinations, according to the criteria provided by the reimbursement rules of the Agenzia Italiana del Farmaco (NOTA 1 and 48). Among 4715 enrolled patients, 3899 were discharged alive. At hospital discharge, 2412 (61.9%, 95%CI: 60.3–63.4%) patients were prescribed with drugs for peptic ulcer and GERD, a 12% of increase from hospital admission. Almost half of the patients (N = 1776, 45.6%, 95%CI: 44.0–47.1%) were inappropriately prescribed or not prescribed: among the drugs for peptic ulcer and GERD users, about 60% (1444/2412) were overprescribed, and among nonusers, 22% (332/1487) were underprescribed. Among patients newly prescribed at hospital discharge, 60% (392/668) were inappropriately prescribed. The appropriateness of drugs for peptic ulcer and GERD therapy decreased by 3% from hospital admission to discharge. Hospitalization missed the opportunity to improve the quality of prescription of this class of drug.

Published
2019

39. GIGJ: a crustal gravity model of the Guangdong Province for predicting the geoneutrino signal at the JUNO experiment

Author

Monica Sisti, Agnese Giaz, Stefano Maria Mari, A. Brigatti, Severino Angelo Maria Bussino, C. Sirignano, Vito Antonelli, F. Dal Corso, D. Pedretti, Giuseppe Verde, R. Brugnera, Roberto Isocrate, G. Galet, Ivano Lippi, M. Montuschi, Daniele Sampietro, G. Salamanna, Massimiliano Nastasi, Marco Grassi, Antonio Budano, Antonio Insolia, Cristina Martellini, Andrey Formozov, Xuefeng Ding, Alessandra Re, Marco Giammarchi, Fabio Mantovani, G. Fiorentini, Enrico Bernieri, E. Meroni, Filippo Marini, Fatma Sawy, M. Buscemi, D. Lo Presti, Alessandro Paoloni, Mauro Mezzetto, Marica Baldoncini, Fausto Ortica, Yury Malyshkin, Daniele Corti, Virginia Strati, Mirko Reguzzoni, Salvatore Monforte, Giulio Settanta, Luca Stanco, Giuseppe Andronico, Piero Poli, Andrea Fabbri, Gioacchino Ranucci, Davide Chiesa, A. Garfagnini, Marco Bellato, S. Dusini, Fabio Longhitano, Aldo Romani, R. Pompilio, M. Spinetti, R. Ford, P. Saggese, Lino Miramonti, Ivan Callegari, Paolo Lombardi, N. Pelliccia, Lorenzo Rossi, S. Parmeggiano, Ezio Previtali, Barbara Ricci, Rossella Caruso, Lucia Votano, Institut des Sciences de la Terre (ISTerre), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-PRES Université de Grenoble-Institut de recherche pour le développement [IRD] : UR219-Institut national des sciences de l'Univers (INSU - CNRS)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université Joseph Fourier - Grenoble 1 (UJF), AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Reguzzoni, M., Rossi, L., Baldoncini, M., Callegari, I., Poli, P., Sampietro, D., Strati, V., Mantovani, F., Andronico, G., Antonelli, V., Bellato, M., Bernieri, E., Brigatti, A., Brugnera, R., Budano, A., Buscemi, M., Bussino, S., Caruso, R., Chiesa, D., Corti, D., Dal Corso, F., Ding, X. F., Dusini, S., Fabbri, A., Fiorentini, G., Ford, R., Formozov, A., Galet, G., Garfagnini, A., Giammarchi, M., Giaz, A., Grassi, M., Insolia, A., Isocrate, R., Lippi, I., Longhitano, F., Lo Presti, D., Lombardi, P., Malyshkin, Y., Marini, F., Mari, S. M., Martellini, C., Meroni, E., Mezzetto, M., Miramonti, L., Monforte, S., Montuschi, M., Nastasi, M., Ortica, F., Paoloni, A., Parmeggiano, S., Pedretti, D., Pelliccia, N., Pompilio, R., Previtali, E., Ranucci, G., Re, A. C., Ricci, B., Romani, A., Saggese, P., Salamanna, G., Sawy, F. H., Settanta, G., Sisti, M., Sirignano, C., Spinetti, M., Stanco, L., Verde, G., Votano, L., Centre National de la Recherche Scientifique (CNRS)-PRES Université de Grenoble-Université Joseph Fourier - Grenoble 1 (UJF)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de recherche pour le développement [IRD] : UR219-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry]), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université Joseph Fourier - Grenoble 1 (UJF)-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de recherche pour le développement [IRD] : UR219-PRES Université de Grenoble-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Reguzzoni, M, Rossi, L, Baldoncini, M, Callegari, I, Poli, P, Sampietro, D, Strati, V, Mantovani, F, Andronico, G, Antonelli, V, Bellato, M, Bernieri, E, Brigatti, A, Brugnera, R, Budano, A, Buscemi, M, Bussino, S, Caruso, R, Chiesa, D, Corti, D, Dal Corso, F, Ding, X, Dusini, S, Fabbri, A, Fiorentini, G, Ford, R, Formozov, A, Galet, G, Garfagnini, A, Giammarchi, M, Giaz, A, Grassi, M, Insolia, A, Isocrate, R, Lippi, I, Longhitano, F, Lo Presti, D, Lombardi, P, Malyshkin, Y, Marini, F, Mari, S, Martellini, C, Meroni, E, Mezzetto, M, Miramonti, L, Monforte, S, Montuschi, M, Nastasi, M, Ortica, F, Paoloni, A, Parmeggiano, S, Pedretti, D, Pelliccia, N, Pompilio, R, Previtali, E, Ranucci, G, Re, A, Ricci, B, Romani, A, Saggese, P, Salamanna, G, Sawy, F, Settanta, G, Sisti, M, Sirignano, C, Spinetti, M, Stanco, L, Verde, G, Votano, L, Reguzzoni M., Rossi L., Baldoncini M., Callegari I., Poli P., Sampietro D., Strati V., Mantovani F., Andronico G., Antonelli V., Bellato M., Bernieri E., Brigatti A., Brugnera R., Budano A., Buscemi M., Bussino S., Caruso R., Chiesa D., Corti D., Dal Corso F., Ding X.F., Dusini S., Fabbri A., Fiorentini G., Ford R., Formozov A., Galet G., Garfagnini A., Giammarchi M., Giaz A., Grassi M., Insolia A., Isocrate R., Lippi I., Longhitano F., Lo Presti D., Lombardi P., Malyshkin Y., Marini F., Mari S.M., Martellini C., Meroni E., Mezzetto M., Miramonti L., Monforte S., Montuschi M., Nastasi M., Ortica F., Paoloni A., Parmeggiano S., Pedretti D., Pelliccia N., Pompilio R., Previtali E., Ranucci G., Re A.C., Ricci B., Romani A., Saggese P., Salamanna G., Sawy F.H., Settanta G., Sisti M., Sirignano C., Spinetti M., Stanco L., Verde G., and Votano L.

Subjects
010504 meteorology & atmospheric sciences, Geoneutrino, geophysical uncertaintie, Inverse transform sampling, FOS: Physical sciences, 01 natural sciences, Bayesian method, Upper, middle, and lower crust, Standard deviation, NO, South China Block, middle, Physics - Geophysics, Monte Carlo stochastic optimization, GOCE data gravimetric inversion, Geophysical uncertainties, Geochemistry and Petrology, Earth and Planetary Sciences (miscellaneous), geophysical uncertainties, upper, middle, and lower crust, Image resolution, 0105 earth and related environmental sciences, Subdivision, Jiangmen Underground Neutrino Observatory, upper and middle and lower crust, business.industry, Settore FIS/01 - Fisica Sperimentale, Crust, upper, Geodesy, [PHYS.PHYS.PHYS-GEN-PH]Physics [physics]/Physics [physics]/General Physics [physics.gen-ph], Geophysics (physics.geo-ph), and lower crust, Depth sounding, Geophysics, 13. Climate action, Space and Planetary Science, business, Geology, Bayesian method, geophysical uncertainties, GOCE data gravimetric inversion, Monte Carlo stochastic optimization, South China Block,upper and middle and lower crust
Abstract

Gravimetric methods are expected to play a decisive role in geophysical modeling of the regional crustal structure applied to geoneutrino studies. GIGJ (GOCE Inversion for Geoneutrinos at JUNO) is a 3D numerical model constituted by ~46 x 10$^{3}$ voxels of 50 x 50 x 0.1 km, built by inverting gravimetric data over the 6{\deg} x 4{\deg} area centered at the Jiangmen Underground Neutrino Observatory (JUNO) experiment, currently under construction in the Guangdong Province (China). The a-priori modeling is based on the adoption of deep seismic sounding profiles, receiver functions, teleseismic P-wave velocity models and Moho depth maps, according to their own accuracy and spatial resolution. The inversion method allowed for integrating GOCE data with the a-priori information and regularization conditions through a Bayesian approach and a stochastic optimization. GIGJ fits the homogeneously distributed GOCE gravity data, characterized by high accuracy, with a ~1 mGal standard deviation of the residuals, compatible with the observation accuracy. Conversely to existing global models, GIGJ provides a site-specific subdivision of the crustal layers masses which uncertainties include estimation errors, associated to the gravimetric solution, and systematic uncertainties, related to the adoption of a fixed sedimentary layer. A consequence of this local rearrangement of the crustal layer thicknesses is a ~21% reduction and a ~24% increase of the middle and lower crust expected geoneutrino signal, respectively. Finally, the geophysical uncertainties of geoneutrino signals at JUNO produced by unitary uranium and thorium abundances distributed in the upper, middle and lower crust are reduced by 77%, 55% and 78%, respectively. The numerical model is available at http://www.fe.infn.it/u/radioactivity/GIGJ, Comment: 35 pages, 9 figures, 4 tables

Published
2019

40. Distillation and stripping pilot plants for the JUNO neutrino detector: Design, operations and reliability

Author

D. Corti, Andrea Fabbri, Giuseppe Verde, S. Bussino, H. Steiger, R. Pompilio, Yury Malyshkin, L. Votano, E. Bernier, Nicomede Pelliccia, R. Brugnera, Aldo Romani, A. Mengucci, Lino Miramonti, Augusto Brigatti, E. Meroni, Filippo Marini, Salvatore Monforte, Chiara Sirignano, Monica Sisti, Andrey Formozov, Gioacchino Ranucci, Marco Grassi, D. Riondino, Agnese Giaz, Davide Chiesa, A. Garfagnini, Alessandra Re, R. Gaigher, Paolo Montini, Catia Clementi, Ezio Previtali, Massimiliano Nastasi, S. Parmeggiano, Barbara Ricci, Fabio Mantovani, R. J. Ford, Marco Giammarchi, Rossella Caruso, Giuseppe Salamanna, Mario Buscemi, P. Saggese, G. Galet, Ivano Lippi, Antonio Budano, Giovanni Fiorentini, F. Dal Corso, Wilfried Depnering, Fausto Ortica, Cristina Martellini, S. Franke, Jari Joutsenvaara, Giulio Settanta, Stefano Maria Mari, Vito Antonelli, Roberto Isocrate, Virginia Strati, G. Andronico, Paolo Lombardi, Alessandro Paoloni, Agnese Martini, Fatma Sawy, Luca Stanco, M. Montuschi, D. Pedretti, Xuefeng Ding, A. Insolia, M. Mezzetto, Marica Baldoncini, M. Bellato, S. Dusini, AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Lombardi, P, Montuschi, M, Formozov, A, Brigatti, A, Parmeggiano, S, Pompilio, R, Depnering, W, Franke, S, Gaigher, R, Joutsenvaara, J, Mengucci, A, Meroni, E, Steiger, H, Mantovani, F, Ranucci, G, Andronico, G, Antonelli, V, Baldoncini, M, Bellato, M, Bernier, E, Brugnera, R, Budano, A, Buscemi, M, Bussino, S, Caruso, R, Chiesa, D, Clementi, C, Corti, D, Dal Corso, F, Ding, X, Dusini, S, Fabbri, A, Fiorentini, G, Ford, R, Galet, G, Garfagnini, A, Giammarchi, M, Giaz, A, Grassi, M, Insolia, A, Isocrate, R, Lippi, I, Malyshkin, Y, Mari, S, Marini, F, Martellini, C, Martini, A, Mezzetto, M, Miramonti, L, Monforte, S, Montini, P, Nastasi, M, Ortica, F, Paoloni, A, Pedretti, D, Pelliccia, N, Previtali, E, Re, A, Ricci, B, Riondino, D, Romani, A, Saggese, P, Salamanna, G, Sawy, F, Settanta, G, Sisti, M, Sirignano, C, Stanco, L, Strati, V, Verde, G, Votano, L, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Lombardi, P., Montuschi, M., Formozov, A., Brigatti, A., Parmeggiano, S., Pompilio, R., Depnering, W., Franke, S., Gaigher, R., Joutsenvaara, J., Mengucci, A., Meroni, E., Steiger, H., Mantovani, F., Ranucci, G., Andronico, G., Antonelli, V., Baldoncini, M., Bellato, M., Bernier, E., Brugnera, R., Budano, A., Buscemi, M., Bussino, S., Caruso, R., Chiesa, D., Clementi, C., Corti, D., Dal Corso, F., Ding, X. F., Dusini, S., Fabbri, A., Fiorentini, G., Ford, R., Galet, G., Garfagnini, A., Giammarchi, M., Giaz, A., Grassi, M., Insolia, A., Isocrate, R., Lippi, I., Malyshkin, Y., Mari, S. M., Marini, F., Martellini, C., Martini, A., Mezzetto, M., Miramonti, L., Monforte, S., Montini, P., Nastasi, M., Ortica, F., Paoloni, A., Pedretti, D., Pelliccia, N., Previtali, E., Re, A. C., Ricci, B., Riondino, D., Romani, A., Saggese, P., Salamanna, G., Sawy, F. H., Settanta, G., Sisti, M., Sirignano, C., Stanco, L., Strati, V., Verde, G., Votano, L., Lombardi P., Montuschi M., Formozov A., Brigatti A., Parmeggiano S., Pompilio R., Depnering W., Franke S., Gaigher R., Joutsenvaara J., Mengucci A., Meroni E., Steiger H., Mantovani F., Ranucci G., Andronico G., Antonelli V., Baldoncini M., Bellato M., Bernier E., Brugnera R., Budano A., Buscemi M., Bussino S., Caruso R., Chiesa D., Clementi C., Corti D., Dal Corso F., Ding X.F., Dusini S., Fabbri A., Fiorentini G., Ford R., Galet G., Garfagnini A., Giammarchi M., Giaz A., Grassi M., Insolia A., Isocrate R., Lippi I., Malyshkin Y., Mari S.M., Marini F., Martellini C., Martini A., Mezzetto M., Miramonti L., Monforte S., Montini P., Nastasi M., Ortica F., Paoloni A., Pedretti D., Pelliccia N., Previtali E., Re A.C., Ricci B., Riondino D., Romani A., Saggese P., Salamanna G., Sawy F.H., Settanta G., Sisti M., Sirignano C., Stanco L., Strati V., Verde G., and Votano L.

Subjects
Large-scale experiment, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Liquid scintillator, Attenuation length, LAB, Large-scale experiments, Light yield, Nitrogen purging, Radiopurity, Scintillator transparency, Instrumentation, scintillation counter: liquid, Mixing (process engineering), Full scale, FOS: Physical sciences, fabrication, Scintillator, 01 natural sciences, 7. Clean energy, Stripping (fiber), law.invention, NO, law, 0103 physical sciences, thorium: admixture, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Process engineering, Distillation, background: radioactivity, Nuclear and High Energy Physic, Physics, JUNO, 010308 nuclear & particles physics, business.industry, uranium: admixture, Settore FIS/01 - Fisica Sperimentale, Instrumentation and Detectors (physics.ins-det), Neutrino detector, Neutrino, business, aluminum: oxygen
Abstract

This paper describes the design, construction principles and operations of the distillation and stripping pilot plants tested at the Daya Bay Neutrino Laboratory, with the perspective to adapt these processes, system cleanliness and leak-tightness standards to the final full scale plants to be used for the purification of the liquid scintillator of the JUNO neutrino detector. The main goal of these plants is to remove radio impurities from the liquid scintillator while increasing its optical attenuation length. Purification of liquid scintillator will be performed with a system combining alumina oxide, distillation, water extraction and steam (or N 2 gas) stripping. Such a combined system will aim at obtaining a total attenuation length greater than 20 m @430 nm, and a bulk radiopurity for 238U and 232Th in the 10−15 ÷ 10−17 g/g range. The pilot plants commissioning and operation have also provided valuable information on the degree of reliability of their main components, which will be particularly useful for the design of the final full scale purification equipment for the JUNO liquid scintillator. This paper describes two of the five pilot plants since the Alumina Column, fluorescent material mixing and the Water Extraction plants are being developed by the Chinese part of the collaboration.

Published
2019

41. Inappropriate prescription of benzodiazepines in acutely hospitalized older patients

Author

Carlotta, Franchi, Raffaella, Rossio, Ilaria, Ardoino, Pier Mannuccio Mannucci, Alessandro, Nobili, Domenico, Prisco, Elena, Silvestri, Giacomo, Emmi, Alessandra, Bettiol, Caterina, Cenci, Gianni, Biolo, Michela, Zanetti, Martina, Guadagni, Michele, Zaccari, Massimiliano, Chiuch, Massimo, Vanoli, Giulia, Grignani, Edoardo Alessandro Pulixi, Mauro, Bernardi, Silvia Li Bassi, Luca, Santi, Giacomo, Zaccherini, Graziana, Lupattelli, Elmo, Mannarino, Vanessa, Bianconi, Francesco, Paciullo, Riccardo, Alcidi, Ranuccio, Nuti, Roberto, Valenti, Martina, Ruvio, Silvia, Cappelli, Alberto, Palazzuoli, Domenico, Girelli, Fabiana, Busti, Giacomo, Marchi, Mario, Barbagallo, Ligia, Dominguez, Floriana, Cocita, Vincenza, Beneduce, Lidia, Plances, Salvatore, Corrao, Giuseppe, Natoli, Salvatore, Mularo, Massimo, Raspanti, Federica, Cavallaro, Marco, Zoli, Ilaria, Lazzari, Mattia, Brunori, Elisa, Fabbri, Donatella, Magalotti, Raffaella, Arnò, Franco Laghi Pasini, Pier Leopoldo Capecchi, Giuseppe, Palasciano, Maria Ester Modeo, Carla Di Gennaro, Maria Domenica Cappellini, Diletta, Maira, Valeria Di Stefano, Giovanna, Fabio, Sonia, Seghezzi, Marta, Mancarella, Margherita Migone De Amicis, Giacomo De Luca, Natalia, Scaramellini, Matteo, Cesari, Paolo Dionigi Rossi, Sarah, Damanti, Marta, Clerici, Federica, Conti, Giulia, Bonini, Barbara Brignolo Ottolini, Antonio Di Sabatino, Emanuela, Miceli, Marco Vincenzo Lenti, Martina, Pisati, Costanza Caccia Dominioni, Giovanni, Murialdo, Alessio, Marra, Federico, Cattaneo, Roberto, Pontremoli, Valentina, Beccati, Giulia, Nobili, Maria Beatrice Secchi, Davide, Ghelfi, Luigi, Anastasio, Lucia, Sofia, Maria, Carbone, Francesco, Cipollone, Maria Teresa Guagnano, Emanuele, Valeriani, Ilaria, Rossi, Gerardo, Mancuso, Daniela, Calipari, Mosè, Bartone, Giuseppe, Delitala, Maria, Berria, Chiara, Pes, Alessandro, Delitala, Maurizio, Muscaritoli, Alessio, Molfino, Enrico, Petrillo, Giuseppe, Zuccalà, Gabriella, D’Aurizio, Giuseppe, Romanelli, Alessandra, Marengoni, Alberto, Zucchelli, Francesca, Manzoni, Andrea, Volpini, Antonio, Picardi, Umberto Vespasiani Gentilucci, Paolo, Gallo, Chiara, Dell’Unto, Giorgio, Annoni, Maurizio, Corsi, Giuseppe, Bellelli, Sara, Zazzetta, Paolo, Mazzola, Hajnalka, Szabo, Alessandra, Bonfanti, Franco, Arturi, Elena, Succurro, Mariangela, Rubino, Bruno, Tassone, Giorgio, Sesti, Maria Grazia Serra, Maria Antonietta Bleve, Laura, Gasbarrone, Maria Rosaria Sajeva, Antonio, Brucato, Silvia, Ghidoni, Fabrizio, Fabris, Irene, Bertozzi, Giulia, Bogoni, Maria Victoria Rabuini, Elisabetta, Cosi, Paolo, Scarinzi, Annalisa, Amabile, Elisabetta, Omenetto, Tancredi, Prandini, Manfredini, Roberto, Fabbian, Fabio, Benedetta, Boari, Alfredo De Giorgi, Ruana, Tiseo, DE GIORGIO, Roberto, Giuseppe, Paolisso, Maria Rosaria Rizzo, Claudio, Borghi, Enrico, Strocchi, Eugenia, Ianniello, Mario, Soldati, Carlo, Sabbà, Francesco Saverio Vella, Patrizia, Suppressa, Pasquale, Agosti, Andrea, Schilardi, Francesca, Loparco, Giovanni Michele De Vincenzo, Alessio, Comitangelo, Emanuele, Amoruso, Luigi, Fenoglio, Andrea, Falcetta, Christian, Bracco, Fracanzani, Anna L., Silvia, Fargion, Silvia, Tiraboschi, Annalisa, Cespiati, Giovanna, Oberti, Giordano, Sigon, Flora, Peyvandi, Barbara, Ferrari, Giulia, Colombo, Valter, Monzani, Valeria, Savojardo, Christian, Folli, Giuliana, Ceriani, Francesco, Salerno, Giada, Pallini, Franco, Dallegri, Luciano, Ottonello, Luca, Liberale, Lara, Caserza, Kassem, Salam, Nicola Lucio Liberato, Tiziana, Tognin, Giovanni Battista Bianchi, Sabrina, Giaquinto, Francesco, Purrello, Antonino Di Pino, Salvatore, Piro, Renzo, Rozzini, Lina, Falanga, Elena, Spazzini, Camillo, Ferrandina, Giuseppe, Montrucchio, Paolo, Petitti, Paolo, Peasso, Edoardo, Favale, Cesare, Poletto, Raffaella, Salmi, Piergiorgio, Gaudenzi, Francesco, Violi, Ludovica, Perri, Raffaele, Landolfi, Massimo, Montalto, Antonio, Mirijello, Luigina, Guasti, Luana, Castiglioni, Andrea, Maresca, Alessandro, Squizzato, Leonardo, Campiotti, Alessandra, Grossi, Marco, Bertolotti, Chiara, Mussi, Giulia, Lancellotti, Maria Vittoria Libbra, Giulia, Dondi, Elisa, Pellegrini, Lucia, Carulli, Matteo, Galassi, Yasmine, Grassi, Francesco, Perticone, Maria, Perticone, Rosa, Battaglia, Marco, Filice, Raffaele, Maio, Vincenzo, Stanghellini, Eugenio, Ruggeri, Sara del Vecchio, Andrea, Salvi, Roberto, Leonardi, Giampaolo, Damiani, William, Capeci, Armando, Gabrielli, Massimo, Mattioli, Giuseppe Pio Martino, Lorenzo, Biondi, Pietro, Pettinari, Riccardo, Ghio, Anna Dal Col, Salvatore, Minisola, Luciano, Colangelo, Mirella, Cilli, Giancarlo, Labbadia, Antonella, Afeltra, Benedetta, Marigliano, Maria Elena Pipita, Pietro, Castellino, Luca, Zanoli, Samuele, Pignataro, Alfio, Gennaro, Julien, Blanco, Valter, Saracco, Marisa, Fogliati, Carlo, Bussolino, Francesca, Mete, Miriam, Gino, Antonio, Cittadini, Carlo, Vigorito, Michele, Arcopinto, Andrea, Salzano, Emanuele, Bobbio, Alberto Maria Marra, Domenico, Sirico, Guido, Moreo, Francesca, Gasparini, Silvia, Prolo, Gloria, Pina, Alberto, Ballestrero, Fabio, Ferrando, Sergio, Berra, Simonetta, Dassi, Maria Cristina Nava, Bruno, Graziella, Stefano, Baldassarre, Salvatore, Fragapani, Gabriella, Gruden, Giorgio, Galanti, Gabriele, Mascherini, Cristian, Petri, Laura, Stefani, Margherita, Girino, Valeria, Piccinelli, Francesco, Nasso, Vincenza, Gioffrè, Maria, Pasquale, Giuseppe, Scattolin, Sergio, Martinelli, Mauro, Turrin, Leonardo, Sechi, Cristina, Catena, Gianluca, Colussi, Nicola, Passariello, Luca, Rinaldi, Franco, Berti, Giuseppe, Famularo, Patrizia, Tarsitani, Roberto, Castello, Michela, Pasino, Gian Paolo Ceda, Marcello Giuseppe Maggio, Simonetta, Morganti, Andrea, Artoni, Stefano Del Giacco, Davide, Firinu, Francesca, Losa, Giovanni, Paoletti, Giulia, Costanzo, Giuseppe, Montalto, Anna, Licata, Valentina, Malerba, Filippo Alessandro Montalto, Antonino, Lasco, Giorgio, Basile, Antonino, Catalano, Lorenzo, Malatino, Benedetta, Stancanelli, Valentina, Terranova, Salvatore Di Marca, Rosario Di Quattro, Lara La Malfa, Rossella, Caruso, Patrizia, Mecocci, Carmelinda, Ruggiero, Virginia, Boccardi, Tiziana, Meschi, Fulvio, Lauretani, Andrea, Ticinesi, Antonio, Nouvenne, Pietro, Minuz, Luigi, Fondrieschi, Mario, Pirisi, Gian Paolo Fra, Daniele, Sola, Massimo, Porta, Piero, Riva, Roberto, Quadri, Erica, Larovere, Marco, Novelli, Giorgio, Scanzi, Caterina, Mengoli, Stella, Provini, Laura, Ricevuti, Emilio, Simeone, Rosa, Scurti, Fabio, Tolloso, Roberto, Tarquini, Alice, Valoriani, Silvia, Dolenti, Giulia, Vannini, Alberto, Tedeschi, Lucia, Trotta, Riccardo, Volpi, Pietro, Bocchi, Alessandro, Vignali, Sergio, Harari, Chiara, Lonati, Mara, Cattaneo, Federico, Napoli., Franchi, C., Rossio R., Ardoino I., Mannucci P. M., Nobili A., and Rinaldi, Luca

Subjects
Male, medicine.medical_specialty, Beers Criteria, Socio-culturale, Inappropriate Prescribing, Hypnotic, 03 medical and health sciences, Benzodiazepines, 0302 clinical medicine, Older patients, Older peopl, Internal medicine and geriatric wards, Appropriateness of prescription, Benzodiazepine, Hypnotics, Older people, REPOSI register, 80 and over, Medicine, Humans, Pharmacology (medical), Medical prescription, Biological Psychiatry, Aged, Pharmacology, Aged, 80 and over, business.industry, Settore MED/09 - MEDICINA INTERNA, Patient Discharge, 030227 psychiatry, Hospitalization, Psychiatry and Mental health, Internal medicine and geriatric ward, Increased risk, Neurology, Hospital admission, Emergency medicine, Female, Neurology (clinical), business, Nursing homes, Appropriateness of prescription, Benzodiazepine, Hypnotics, Internal medicine and geriatric wards, Older peopl, 030217 neurology & neurosurgery, Human
Abstract

Benzodiazepines (BDZs) are widely prescribed in older people. The aims of the study are to assess the prevalence of inappropriate prescription of BZDs and the associated factors in acutely hospitalized older patients. Patients aged 65 years or more hospitalized from 2010 to 2017 in more than 100 Italian internal medicine and geriatric wards in the frame of the REPOSI register were included if prescribed with BDZs at hospital admission or discharge. Appropriateness of prescription was assessed according to the 2015 Beers criteria and their modified French and German versions. Among 4681 patients discharged from hospital, 15% (N = 710) were discharged with BDZs, and 62% of them (N = 441, 95% CI: 58.5%–65.6%) were inappropriately prescribed, being prescribed with BDZ to be always avoided in the elderly (45%), at higher doses than recommended (31%) or with no appropriate clinical conditions (19%). From admission to discharge the prevalence of inappropriate BDZ prescription decreased by 4%, but 62% of patients inappropriately prescribed at admission were still inappropriately prescribed at discharge. Among the 179 patients first prescribed at the time of discharge, half were inappropriately prescribed. Being female (OR 1.32, 95%CI 0.95–1.85), enrolled in REPOSI during the years 2016 and 2017 (OR 1.94, 95%CI 1.10–3.39; OR 1.57, 95%CI 0.95–2.58) and living in nursing homes (OR 2.04, 95%CI 0.95–4.37) were associated with an increased risk to be inappropriately prescribed. This study shows a high prevalence of inappropriate use of BDZ in acutely hospitalized older patients both at hospital admission and discharge.

Published
2019

42. Nanoseconds Timing System Based on IEEE 1588 FPGA Implementation

Author

Antonio Insolia, Enrico Bernieri, Alessandro Paoloni, G. Salamanna, Antonio Budano, Marco Giammarchi, Virginia Strati, Lino Miramonti, Andrey Formozov, C. Sirignano, R. Brugnera, D. Pedretti, Ezio Previtali, Marco Bellato, Andrea Fabbri, Giulio Settanta, F. Dal Corso, Barbara Ricci, Fabio Mantovani, Fatma Sawy, Paolo Lombardi, R. Ford, M. Buscemi, Paolo Montini, Severino Angelo Maria Bussino, Marco Grassi, Rossella Caruso, Catia Clementi, Fausto Ortica, Cristina Martellini, S. Dusini, Monica Sisti, Roberto Isocrate, Agnese Giaz, Ashlie Martini, Salvatore Monforte, A. Brigatti, Daniele Corti, Marica Baldoncini, Massimiliano Nastasi, Alessandra Re, Giuseppe Andronico, Aldo Romani, Stefano Maria Mari, Vito Antonelli, Xuefeng Ding, G. Galet, Ivano Lippi, Davide Chiesa, A. Garfagnini, Giuseppe Verde, E. Meroni, Filippo Marini, Gioacchino Ranucci, Luca Stanco, M. Montuschi, Antonio Bergnoli, Pedretti D., Bellato M., Isocrate R., Bergnoli A., Brugnera R., Corti D., Dal Corso F., Galet G., Garfagnini A., Giaz A., Lippi I., Marini F., Andronico G., Antonelli V., Baldoncini M., Bernieri E., Brigatti A., Budano A., Buscemi M., Bussino S., Caruso R., Chiesa D., Clementi C., Ding X.F., Dusini S., Fabbri A., Ford R., Formozov A., Giammarchi M., Grassi M., Insolia A., Lombardi P., Mantovani F., Mari S.M., Martellini C., Martini A., Meroni E., Miramonti L., Monforte S., Montini P., Montuschi M., Nastasi M., Ortica F., Paoloni A., Previtali E., Ranucci G., Re A.C., Ricci B., Romani A., Salamanna G., Sawy F.H., Settanta G., Sisti M., Sirignano C., Stanco L., Strati V., Verde G., Pedretti, D, Bellato, M, Isocrate, R, Bergnoli, A, Brugnera, R, Corti, D, Dal Corso, F, Galet, G, Garfagnini, A, Giaz, A, Lippi, I, Marini, F, Andronico, G, Antonelli, V, Baldoncini, M, Bernieri, E, Brigatti, A, Budano, A, Buscemi, M, Bussino, S, Caruso, R, Chiesa, D, Clementi, C, Ding, X, Dusini, S, Fabbri, A, Ford, R, Formozov, A, Giammarchi, M, Grassi, M, Insolia, A, Lombardi, P, Mantovani, F, Mari, S, Martellini, C, Martini, A, Meroni, E, Miramonti, L, Monforte, S, Montini, P, Montuschi, M, Nastasi, M, Ortica, F, Paoloni, A, Previtali, E, Ranucci, G, Re, A, Ricci, B, Romani, A, Salamanna, G, Sawy, F, Settanta, G, Sisti, M, Sirignano, C, Stanco, L, Strati, V, Verde, G, Pedretti, D., Bellato, M., Isocrate, R., Bergnoli, A., Brugnera, R., Corti, D., Dal Corso, F., Galet, G., Garfagnini, A., Giaz, A., Lippi, I., Marini, F., Andronico, G., Antonelli, V., Baldoncini, M., Bernieri, E., Brigatti, A., Budano, A., Buscemi, M., Bussino, S., Caruso, R., Chiesa, D., Clementi, C., Ding, X. F., Dusini, S., Fabbri, A., Ford, R., Formozov, A., Giammarchi, M., Grassi, M., Insolia, A., Lombardi, P., Mantovani, F., Mari, S. M., Martellini, C., Martini, A., Meroni, E., Miramonti, L., Monforte, S., Montini, P., Montuschi, M., Nastasi, M., Ortica, F., Paoloni, A., Previtali, E., Ranucci, G., Re, A. C., Ricci, B., Romani, A., Salamanna, G., Sawy, F. H., Settanta, G., Sisti, M., Sirignano, C., Stanco, L., Strati, V., and Verde, G.

Subjects
Ethernet, FOS: Computer and information sciences, Nuclear and High Energy Physics, Eye diagram, field-programmable gate arrays (FPGAs), front-end electronics, hardware, synchronization, timing system, front-end electronic, Serial communication, Data buffer, Network topology, 01 natural sciences, Clock synchronization, NO, Computer Science - Networking and Internet Architecture, PE2_2, 0103 physical sciences, Synchronization (computer science), Electrical and Electronic Engineering, Networking and Internet Architecture (cs.NI), 010308 nuclear & particles physics, business.industry, Settore FIS/01 - Fisica Sperimentale, Nuclear Energy and Engineering, Precision Time Protocol, business, Computer hardware, Data link layer
Abstract

Clock synchronization procedures are mandatory in most physical experiments where event fragments are readout by spatially dislocated sensors and must be glued together to reconstruct key parameters (e.g. energy, interaction vertex etc.) of the process under investigation. These distributed data readout topologies rely on an accurate time information available at the frontend, where raw data are acquired and tagged with a precise timestamp prior to data buffering and central data collecting. This makes the network complexity and latency, between frontend and backend electronics, negligible within upper bounds imposed by the frontend data buffer capability. The proposed research work describes an FPGA implementation of IEEE 1588 Precision Time Protocol (PTP) that exploits the CERN Timing, Trigger and Control (TTC) system as a multicast messaging physical and data link layer. The hardware implementation extends the clock synchronization to the nanoseconds range, overcoming the typical accuracy limitations inferred by computers Ethernet based Local Area Network (LAN). Establishing a reliable communication between master and timing receiver nodes is essential in a message-based synchronization system. In the backend electronics, the serial data streams synchronization with the global clock domain is guaranteed by an hardware-based finite state machine that scans the bit period using a variable delay chain and finds the optimal sampling point. The validity of the proposed timing system has been proved in point-to-point data links as well as in star topology configurations over standard CAT-5e cables. The results achieved together with weaknesses and possible improvements are hereby detailed., Comment: 8 pages, 14 figures, proceedings of 21st IEEE Real Time Conference Colonial Williamsburg 9-15 June 2018

Published
2019

43. Ultra-violet imaging of the night-time earth by EUSO-Balloon towards space-based ultra-high energy cosmic ray observations

Author

A. Anzalone, Toshiyuki Nonaka, Javier Licandro, K. Benmessai, B. Beldjilali, E. Kuznetsov, N. Blanc, J. L. Marcos, G. Puehlhofer, T. Djemil, Toshiki Tajima, Giuseppe Giraudo, A. Kedadra, K. S. Caballero, M. Di Martino, M. Ave Pernas, S. Blin-Bondil, G. Cordero, H. Khales, L. Allen, P. Baragatti, A. Marini, Hitoshi Ohmori, Alberto Cellino, Hiroyuki Sagawa, I. Dutan, Yoshiya Kawasaki, T. Napolitano, malek mastafa, B. A. Khrenov, Sebastián Franchini, T. Paul, G. Cotto, C. De Donato, I. Stan, P. Gorodetzky, A. Pagliaro, S. Jeong, J. Watanabe, Piergiorgio Picozza, D. Allard, M. Suzuki, L. López Campano, Soon-Wook Kim, J. Rabanal, G. Osteria, Guillaume Prévôt, O. Larsson, L. R. Wiencke, A. Ebersoldt, Yoshio Arai, Francesca Bisconti, J. Hernández Carretero, Katsuhiko Tsuno, I. Kreykenbohm, D. Kolev, A. Radu, N. Tajima, M. Takeda, Shigehiro Nagataki, A. Guzmán, C. Lachaud, Christer Fuglesang, José Meseguer, A. Menshikov, Osvaldo Catalano, Silvia Ferrarese, R. Greg, J. Mimouni, C. González Alvarado, M. E. Bertaina, Valentina Scotti, M. Bogomilov, N. Mebarki, Y. Martín, C. De Santis, Ken'ichi Nomoto, G. Chiritoi, R. Attallah, N. Tone, K. Martens, Valerie Connaughton, Angel Sanz-Andrés, L. Marcelli, G. Masciantonio, I. S. Zgura, J. Tubbs, Hirohiko M. Shimizu, Austin Cummings, M. Wille, H. Krantz, F. Kajino, A. Jung, Y. Tsunesada, Y. Uchihori, A. La Barbera, H. Lahmar, Daisuke Yonetoku, G. Medina-Tanco, Mohammed Bakiri, Maciej Rybczyński, K. Kudela, J. F. Krizmanic, J. Genci, Konstantin Belov, F.J. Ronga, Yoshimasa Kurihara, C. Moretto, A. Diaz Damian, Jin Yong Lee, H. Schieler, Alfonso Monaco, Antonella Castellina, Mitsuteru Sato, N. Inoue, L. del Peral, A. Franceschi, E. Parizot, Z. Polonsky, Humberto Ibarguen Salazar, T. Shirahama, T. Jammer, Santiago Pindado, Junpei Fujimoto, G. Abdellaoui, L. Villaseñor, Y. Hachisu, G. Roudil, H. Tokuno, Pavol Bobik, F. Perfetto, Hajime Yano, O. Martinez, Bruno Spataro, Tokonatsu Yamamoto, S. Kalli, M. Yu. Zotov, John N. Matthews, Katsuaki Asano, Estíbaliz Gascón, B. Harlov, Carlo Vigorito, Roberto Bellotti, K. Mase, R. Nava, B. Pastirčák, J. Watts, E. Bozzo, S. Turriziani, Toshikazu Ebisuzaki, M. A. Mendoza, Pierre Barrillon, S. Briz, Eduardo García-Ortega, M. Sanz Palomino, E. M. Popescu, Barbara Szabelska, W. Painter, James H. Adams, Sergei A. Sharakin, Rossella Caruso, M. Vrabel, P. Prat, Francesco Isgrò, S. Bartocci, M. Traïche, Josef Jochum, Piero Vallania, M. D. Sabau, Z. Sahnoune, J. A. Morales de los Ríos, T. Peter, S. Naitamor, R. Tsenov, Tomás Belenguer, J. C. Sanchez Balanzar, Gustavo Alonso, F. Cafagna, W. Marszał, Satoshi Wada, Toshitaka Kajino, Piotr Orleanski, J.N. Capdevielle, R. Young, D. Campana, F. Lakhdari, T. Ogawa, W. Hidber Cruz, Thomas Schanz, Daisuke Ikeda, E. Joven, Inkyu Park, N. Belkhalfa, Francesca Capel, P. Galeotti, A. Pollini, Pavel Klimov, B. Panico, M. C. Talai, S. Bacholle, A. J. de Castro, M. Putis, M. Haiduc, Lech Wiktor Piotrowski, Susumu Inoue, S. S. Meyer, Francesco Fenu, S. B. Thomas, H. Miyamoto, Livio Conti, Angela V. Olinto, H. Attoui, Ovidiu Vaduvescu, C. Tenzer, T. Sugiyama, J. Błȩcki, Sergio Fernández-González, R. Matev, J. F. Valdés-Galicia, J. Bayer, Claudio Cassardo, Andrea Santangelo, A. Neronov, L. G. Tkachev, Simona Toscano, A. Weindl, A. Zuccaro Marchi, M. C. Maccarone, M. Fouka, S. Mackovjak, S. Yoshida, J. Szabelski, L. Caramete, Jörn Wilms, Takayuki Tomida, Dmitri Semikoz, C. de la Taille, Naoto Sakaki, C. Catalano, G. Vankova, D. Supanitsky, Mark Christl, O. Tibolla, O. A. Saprykin, Yoshitaka Itow, K. Katahira, A. Belov, H. Prieto, A. Caramete, R. Cremonini, Andrés Merino, Hajime Takami, F. López, M. Rezazadeh, S. Selmane, D. Maravilla, S. Biktemerova, Masaki Fukushima, E. G. Judd, Isabel Pérez-Grande, Shinsuke Abe, P. Carlson, F. Sarazin, A. Haungs, S. Piraino, Kenji Shinozaki, Zbigniew Wlodarczyk, H. J. Crawford, Gali Garipov, Marc Weber, R. Weigand Muñoz, A. Kusenko, S. Pliego, M. Martucci, Shoichi Ogio, Y. Karadzhov, M. Flamini, J. Yang, B. Vlcek, Y. Takizawa, Amine Ahriche, L. Placidi, P. L. Biermann, M. D. Rodríguez Frías, M. Kleifges, I. Rusinov, Z. Plebaniak, I. V. Yashin, K. Kawai, Michiyuki Chikawa, Marcos Reyes, Akinori Saito, S. E. Csorna, Johannes Eser, M. Serra, Luis A. Anchordoqui, A. Bruno, Jeong-Sook Kim, I. Kaneko, T. Patzak, Yoshihiko Mizumoto, J. Karczmarczyk, G. Sáez Cano, Fausto Guarino, P. von Ballmoos, M. Ricci, S. Dagoret-Campagne, Yukihiro Takahashi, José Luis Sánchez, Marco Casolino, Claudio Fornaro, Mikhail Panasyuk, Ralph Engel, Takahiro Fujii, M. Mahdi, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Organisation de Micro-Électronique Générale Avancée (OMEGA), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Abdellaoui, G., Abe, S., Adams, J. H., Ahriche, A., Allard, D., Allen, L., Alonso, G., Anchordoqui, L., Anzalone, A., Arai, Y., Asano, K., Attallah, R., Attoui, H., Ave Pernas, M., Bacholle, S., Bakiri, M., Baragatti, P., Barrillon, P., Bartocci, S., Bayer, J., Beldjilali, B., Belenguer, T., Belkhalfa, N., Bellotti, R., Belov, A., Belov, K., Benmessai, K., Bertaina, M., Biermann, P. L., Biktemerova, S., Bisconti, F., Blanc, N., Blecki, J., Blin-Bondil, S., Bobik, P., Bogomilov, M., Bozzo, E., Briz, S., Bruno, A., Caballero, K. S., Cafagna, F., Campana, D., Capdevielle, J. -N., Capel, F., Caramete, A., Caramete, L., Carlson, P., Caruso, R., Casolino, M., Cassardo, C., Castellina, A., Catalano, C., Catalano, O., Cellino, A., Chikawa, M., Chiritoi, G., Christl, M. J., Connaughton, V., Conti, L., Cordero, G., Cotto, G., Crawford, H. J., Cremonini, R., Csorna, S., Cummings, A., Dagoret-Campagne, S., de Castro, A. J., De Donato, C., de la Taille, C., De Santis, C., del Peral, L., Di Martino, M., Diaz Damian, A., Djemil, T., Dutan, I., Ebersoldt, A., Ebisuzaki, T., Engel, R., Eser, J., Fenu, F., Fernandez-Gonzalez, S., Ferrarese, S., Flamini, M., Fornaro, C., Fouka, M., Franceschi, A., Franchini, S., Fuglesang, C., Fujii, T., Fujimoto, J., Fukushima, M., Galeotti, P., Garcia-Ortega, E., Garipov, G., Gascon, E., Genci, J., Giraudo, G., Gonzalez Alvarado, C., Gorodetzky, P., Greg, R., Guarino, F., Guzman, A., Hachisu, Y., Haiduc, M., Harlov, B., Haungs, A., Hernandez Carretero, J., Hidber Cruz, W., Ikeda, D., Inoue, N., Inoue, S., Isgro, F., Itow, Y., Jammer, T., Jeong, S., Joven, E., Judd, E. G., Jung, A., Jochum, J., Kajino, F., Kajino, T., Kalli, S., Kaneko, I., Karadzhov, Y., Karczmarczyk, J., Katahira, K., Kawai, K., Kawasaki, Y., Kedadra, A., Khales, H., Khrenov, B. A., Kim, J. -S., Kim, S. -W., Kleifges, M., Klimov, P. A., Kolev, D., Krantz, H., Kreykenbohm, I., Krizmanic, J. F., Kudela, K., Kurihara, Y., Kusenko, A., Kuznetsov, E., La Barbera, A., Lachaud, C., Lahmar, H., Lakhdari, F., Larsson, O., Lee, J., Licandro, J., Lopez Campano, L., Lopez, F., Maccarone, M. C., Mackovjak, S., Mahdi, M., Maravilla, D., Marcelli, L., Marcos, J. L., Marini, A., Marszal, W., Martens, K., Martin, Y., Martinez, O., Martucci, M., Masciantonio, G., Mase, K., Mastafa, M., Matev, R., Matthews, J. N., Mebarki, N., Medina-Tanco, G., Mendoza, M. A., Menshikov, A., Merino, A., Meseguer, J., Meyer, S. S., Mimouni, J., Miyamoto, H., Mizumoto, Y., Monaco, A., Morales de los Rios, J. A., Moretto, C., Nagataki, S., Naitamor, S., Napolitano, T., Nava, R., Neronov, A., Nomoto, K., Nonaka, T., Ogawa, T., Ogio, S., Ohmori, H., Olinto, A. V., Orleanski, P., Osteria, G., Pagliaro, A., Painter, W., Panasyuk, M. I., Panico, Beatrice, Parizot, E., Park, I. H., Pastircak, B., Patzak, T., Paul, T., Perez-Grande, I., Perfetto, F., Peter, T., Picozza, P., Pindado, S., Piotrowski, L. W., Piraino, S., Placidi, L., Plebaniak, Z., Pliego, S., Pollini, A., Polonsky, Z., Popescu, E. M., Prat, P., Prevot, G., Prieto, H., Puehlhofer, G., Putis, M., Rabanal, J., Radu, A. A., Reyes, M., Rezazadeh, M., Ricci, M., Rodriguez Frias, M. D., Ronga, F., Roudil, G., Rusinov, I., Rybczynski, M., Sabau, M. D., Saez Cano, G., Sagawa, H., Sahnoune, Z., Saito, A., Sakaki, N., Salazar, H., Sanchez Balanzar, J. C., Sanchez, J. L., Santangelo, A., Sanz-Andres, A., Sanz Palomino, M., Saprykin, O., Sarazin, F., Sato, M., Schanz, T., Schieler, H., Scotti, V., Selmane, S., Semikoz, D., Serra, M., Sharakin, S., Shimizu, H. M., Shinozaki, K., Shirahama, T., Spataro, B., Stan, I., Sugiyama, T., Supanitsky, D., Suzuki, M., Szabelska, B., Szabelski, J., Tajima, N., Tajima, T., Takahashi, Y., Takami, H., Takeda, M., Takizawa, Y., Talai, M. C., Tenzer, C., Thomas, S. B., Tibolla, O., Tkachev, L., Tokuno, H., Tomida, T., Tone, N., Toscano, S., Traiche, M., Tsenov, R., Tsunesada, Y., Tsuno, K., Tubbs, J., Turriziani, S., Uchihori, Y., Vaduvescu, O., Valdes-Galicia, J. F., Vallania, P., Vankova, G., Vigorito, C., Villasenor, L., Vlcek, B., von Ballmoos, P., Vrabel, M., Wada, S., Watanabe, J., Watts, J., Weber, M., Weigand Munoz, R., Weindl, A., Wiencke, L., Wille, M., Wilms, J., Wlodarczyk, Z., Yamamoto, T., Yang, J., Yano, H., Yashin, I. V., Yonetoku, D., Yoshida, S., Young, R., Zgura, I. S., Zotov, M. Y., Zuccaro Marchi, A., Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut national des sciences de l'Univers (INSU - CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), and Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS)

Subjects
lens, air, media_common.quotation_subject, tube, JEM-EUSO, Extensive air shower, Airglow, EUSO-Balloon, Ultra-high energy cosmic ray, 7. Clean energy, 01 natural sciences, detector: fluorescence, Aeronáutica, pixel, 0103 physical sciences, ultraviolet, Ultra-high-energy cosmic ray, cosmic radiation: UHE, backscatter, 010303 astronomy & astrophysics, particle source, Astrophysique, media_common, Physics, COSMIC cancer database, showers: atmosphere, Settore FIS/05, 010308 nuclear & particles physics, background, photon, Astronomy, imaging, Astronomy and Astrophysics, Astronomie, Photon counting, Universe, observatory, Pathfinder, Refracting telescope, trajectory, Trajectory, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], satellite: orbit
Abstract

The JEM-EUSO (Joint Experiment Missions for the Extreme Universe Space Observatory) program aims at developing Ultra-Violet (UV) fluorescence telescopes for efficient detections of Extensive Air Showers (EASs) induced by Ultra-High Energy Cosmic Rays (UHECRs) from satellite orbit. In order to demonstrate key technologies for JEM-EUSO, we constructed the EUSO-Balloon instrument that consists of a ∼1 m 2 refractive telescope with two Fresnel lenses and an array of multi-anode photo-multiplier tubes at the focus. Distinguishing it from the former balloon-borne experiments, EUSO-Balloon has the capabilities of single photon counting with a gate time of 2.3 µs and of imaging with a total of 2304 pixels. As a pathfinder mission, the instrument was launched for an 8 h stratospheric flight on a moonless night in August 2014 over Timmins, Canada. In this work, we analyze the count rates over ∼2.5 h intervals. The measurements are of diffuse light, e.g. of airglow emission, back-scattered from the Earth's atmosphere as well as artificial light sources. Count rates from such diffuse light are a background for EAS detections in future missions and relevant factor for the analysis of EAS events. We also obtain the geographical distribution of the count rates over a ∼780 km 2 area along the balloon trajectory. In developed areas, light sources such as the airport, mines, and factories are clearly identified. This demonstrates the correct location of signals that will be required for the EAS analysis in future missions. Although a precise determination of count rates is relevant for the existing instruments, the absolute intensity of diffuse light is deduced for the limited conditions by assuming spectra models and considering simulations of the instrument response. Based on the study of diffuse light by EUSO-Balloon, we also discuss the implications for coming pathfinders and future space-based UHECR observation missions., 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2019

44. A facility to validate photomultipliers for the upgrade of the Pierre Auger Observatory

Author

D. Bongiovanni, Danilo Bonanno, D. Lo Presti, Fabio Longhitano, Rossella Caruso, Mario Buscemi, Roberta Colalillo, F. C. T. Barbato, F. Guarino, M. Aglietta, L. Valore, Buscemi, M., Aglietta, M., Barbato, F. C. T., Bonanno, D. L., Bongiovanni, D. G., Caruso, R., Colalillo, R., Guarino, F., Longhitano, F., Lo Presti, D., Valore, L., Buscemi M., Aglietta M., Barbato F.C.T., Bonanno D.L., Bongiovanni D.G., Caruso R., Colalillo R., Guarino F., Longhitano F., Lo Presti D., and Valore L.

Subjects
Physics, Pierre Auger Observatory, Photomultiplier, business.industry, Lasers, Settore FIS/01 - Fisica Sperimentale, Laser, visible and IR photons (vacuum) (photomultipliers, Photon detectors for UV, visible and IR photons (vacuum) (photomultipliers, HPDs, others), Optics, Upgrade, HPDs, Front-end electronics for detector readout, others), business, Photon detectors for UV, Instrumentation, Mathematical Physics
Abstract

The Pierre Auger Observatory is undergoing a major upgrade named AugerPrime with the primary aim to add sensitivity to the mass-composition discrimination of ultrahigh-energy cosmic rays. Two different photomultipliers will be added to each water-Cherenkov station of the surface detector of Observatory. To achieve the scientific goals of AugerPrime these photomultipliers have to ensure a linear response to input-light in a wide range. This paper describes a system developed for the validation of AugerPrime-photomultipliers.

Published
2020

45. EUSO-TA - First results from a ground-based EUSO telescope

Author

N. Inoue, L. del Peral, A. Franceschi, E. Parizot, Pavol Bobik, M. Haiduc, Lech Wiktor Piotrowski, S. Bartocci, J. A. Morales de los Ríos, N. Belkhalfa, Susumu Inoue, S. Yoshida, J. Szabelski, S. B. Thomas, K. Kudela, M. D. Rodríguez Frías, Naoto Sakaki, Z. Plebaniak, Thomas Schanz, Michiyuki Chikawa, M. Di Martino, A. Marini, Toshikazu Ebisuzaki, G. Roudil, B. Harlov, J. F. Valdés-Galicia, G. Osteria, Carlo Vigorito, L. G. Tkachev, Josef Jochum, S. Naitamor, G. Vankova, A. Caramete, Livio Conti, K. Martens, D. Maravilla, L. López Campano, J. Fernández-Soriano, R. Matev, Yoshihiko Mizumoto, Sebastián Franchini, S. Biktemerova, A. Ebersoldt, Daisuke Ikeda, A. Zuccaro Marchi, Hajime Takami, Masaki Fukushima, E. G. Judd, O. Larsson, H. J. Crawford, M. Serra, Jörn Wilms, J. Karczmarczyk, M. Ave Pernas, D. Kolev, H. Krantz, Mohammed Bakiri, Luis A. Anchordoqui, I. Kaneko, O. A. Saprykin, Estíbaliz Gascón, S. Turriziani, A. Belov, Valerie Connaughton, L. Marcelli, Konstantin Belov, A. Anzalone, T. Napolitano, Toshitaka Kajino, Francesco Fenu, N. Tone, Christer Fuglesang, Humberto Ibarguen Salazar, K. Benmessai, A. Guzmán, C. Lachaud, Daisuke Yonetoku, J. Blecki, José Meseguer, Angel Sanz-Andrés, Shinsuke Abe, P. Galeotti, R. Attallah, J. Hernández Carretero, H. Tokuno, B. Beldjilali, Takayuki Tomida, Santiago Pindado, S. Jeong, T. Shirahama, Y. Tsunesada, Junpei Fujimoto, M. Yu. Zotov, Silvia Ferrarese, Katsuaki Asano, Alfonso Monaco, H. Attoui, E. M. Popescu, B. A. Khrenov, A. Pagliaro, J. Genci, L. Villaseñor, C. Tenzer, T. Sugiyama, Piergiorgio Picozza, R. Tsenov, Satoshi Wada, N. Mebarki, W. Painter, Piotr Orleanski, T. Paul, A. Pollini, Pavel Klimov, B. Panico, Y. Karadzhov, Isabel Pérez-Grande, F. Sarazin, Zbigniew Wlodarczyk, Marc Weber, F. Bisconti, C. González Alvarado, Tokonatsu Yamamoto, E. Bozzo, T. Ogawa, M. C. Talai, J.N. Capdevielle, G. Sáez Cano, Angela V. Olinto, Javier Licandro, M. Rezazadeh, Andrea Santangelo, A. Kusenko, Katsuhiko Tsuno, Yoshio Arai, I. Kreykenbohm, Pierre Sokolsky, G. Masciantonio, Y. Martín, S. Selmane, John Belz, L. Placidi, M. Kleifges, P. L. Biermann, Tomás Belenguer, Yoshitaka Itow, N. Tajima, Giuseppe Giraudo, M. Takeda, M. A. Mendoza, G. Medina-Tanco, Shigehiro Nagataki, Barbara Szabelska, T. Peter, O. Martinez, Gordon Thomson, Toshiyuki Nonaka, F. Ronga, Gustavo Alonso, J. Watanabe, J. Tubbs, I. Rusinov, I. V. Yashin, M. Fouka, Osvaldo Catalano, M. Martucci, Fausto Guarino, J. Yang, P. von Ballmoos, M. Ricci, H. Miyamoto, M. Sanz Palomino, S. E. Csorna, Amine Ahriche, Simona Toscano, A. Bruno, Jeong-Sook Kim, Kenji Shinozaki, L. Caramete, Marcos Reyes, Roberto Bellotti, K. Mase, Gali Garipov, Joowon Lee, M. Flamini, B. Vlcek, T. Patzak, James H. Adams, H. Prieto, N. Blanc, R. Cremonini, S. Dagoret-Campagne, Francesca Capel, Y. Takizawa, S. Mackovjak, J. L. Marcos, E. Kuznetsov, G. Puehlhofer, D. Supanitsky, R. Weigand Muñoz, P. Gorodetzky, Shoichi Ogio, Johannes Eser, P. Baragatti, Austin Cummings, M. Wille, Y. Uchihori, A. La Barbera, Guillaume Prévôt, S. Blin-Bondil, R. Greg, I. Stan, G. Cordero, Malek Mustafa, J. Mimouni, M. Bogomilov, Z. Polonski, D. Campana, H. Khales, L. Allen, F. Lakhdari, F. Kajino, Maciej Rybczyński, Inkyu Park, M. Putis, S. S. Meyer, A. Weindl, Mark Christl, O. Tibolla, S. Pliego, K. Kawai, Akinori Saito, Ovidiu Vaduvescu, Claudio Cassardo, Dmitri Semikoz, Andrés Merino, P. Carlson, Yuichiro Tameda, John N. Matthews, M. Traïche, F. Cafagna, E. Joven, Y. Hachisu, F. Perfetto, Bruno Spataro, B. Pastirčák, Pierre Barrillon, Eduardo García-Ortega, Sergei A. Sharakin, Piero Vallania, R. Young, Yukihiro Takahashi, José Luis Sánchez, M. D. Sabau, M. Suzuki, Marco Casolino, Claudio Fornaro, Mikhail Panasyuk, A. Neronov, Sergio Fernández-González, J. Bayer, M. C. Maccarone, Valentina Scotti, C. de la Taille, A. Kedadra, I. Dutan, I. S. Zgura, G. Cotto, K. Katahira, M. Mahdi, C. De Donato, Soon-Wook Kim, Yoshimasa Kurihara, G. Chiritoi, H. Schieler, A. Jung, A. Haungs, S. Piraino, H. Lahmar, Antonella Castellina, Mitsuteru Sato, T. Jammer, J. Rabanal, G. Abdellaoui, Hajime Yano, Heungsu Shin, R. Nava, Ralph Engel, Takahiro Fujii, Rossella Caruso, Toshiki Tajima, Hitoshi Ohmori, K. S. Caballero, Hiroyuki Sagawa, Yoshiya Kawasaki, A. Radu, A. Menshikov, Hirohiko M. Shimizu, T. Djemil, D. Allard, Alberto Cellino, S. Kalli, J. Watts, M. E. Bertaina, C. De Santis, L. R. Wiencke, M. Vrabel, P. Prat, Ken'ichi Nomoto, Z. Sahnoune, W. Hidber Cruz, S. Bacholle, Francesco Isgrò, W. Marszał, J. C. Sanchez Balanzar, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Organisation de Micro-Électronique Générale Avancée (OMEGA), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut national des sciences de l'Univers (INSU - CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Abdellaoui, G., Abe, S., Adams, J., Ahriche, A., Allard, D., Allen, L., Alonso, G., Anchordoqui, L., Anzalone, A., Arai, Y., Asano, K., Attallah, R., Attoui, H., Ave Pernas, M., Bacholle, S., Bakiri, M., Baragatti, P., Barrillon, P., Bartocci, S., Bayer, J., Beldjilali, B., Belenguer, T., Belkhalfa, N., Bellotti, R., Belov, A., Belov, K., Belz, J. W., Benmessai, K., Bertaina, M., Biermann, P. L., Biktemerova, S., Bisconti, F., Blanc, N., Blecki, J., Blin-Bondil, S., Bobik, P., Bogomilov, M., Bozzo, E., Bruno, A., Caballero, K. S., Cafagna, F., Campana, D., Capdevielle, J-N., Capel, F., Caramete, A., Caramete, L., Carlson, P., Caruso, R., Casolino, M., Cassardo, C., Castellina, A., Catalano, O., Cellino, A., Chikawa, M., Chiritoi, G., Christl, M. J., Connaughton, V., Conti, L., Cordero, G., Cotto, G., Crawford, H. J., Cremonini, R., Csorna, S., Cummings, A., Dagoret-Campagne, S., De Donato, C., de la Taille, C., De Santis, C., del Peral, L., Di Martino, M., Djemil, T., Dutan, I., Ebersoldt, A., Ebisuzaki, T., Engel, R., Eser, J., Fenu, F., Fernández-González, S., Fernández-Soriano, J., Ferrarese, S., Flamini, M., Fornaro, C., Fouka, M., Franceschi, A., Franchini, S., Fuglesang, C., Fujii, T., Fujimoto, J., Fukushima, M., Galeotti, P., García-Ortega, E., Garipov, G., Gascón, E., Genci, J., Giraudo, G., González Alvarado, C., Gorodetzky, P., Greg, R., Guarino, F., Guzmán, A., Hachisu, Y., Haiduc, M., Harlov, B., Haungs, A., Hernández Carretero, J., Hidber Cruz, W., Ikeda, D., Inoue, N., Inoue, S., Isgrò, F., Itow, Y., Jammer, T., Jeong, S., Joven, E., Judd, E., Jung, A., Jochum, J., Kajino, F., Kajino, T., Kalli, S., Kaneko, I., Karadzhov, Y., Karczmarczyk, J., Katahira, K., Kawai, K., Kawasaki, Y., Kedadra, A., Khales, H., Khrenov, B. A., Kim, Jeong-Sook, Kim, Soon-Wook, Kleifges, M., Klimov, P. A., Kolev, D., Krantz, H., Kreykenbohm, I., Kudela, K., Kurihara, Y., Kusenko, A., Kuznetsov, E., La Barbera, A., Lachaud, C., Lahmar, H., Lakhdari, F., Larsson, O., Lee, J., Licandro, J., López Campano, L., Maccarone, M. C., Mackovjak, S., Mahdi, M., Maravilla, D., Marcelli, L., Marcos, J., Marini, A., Marszal, W., Martens, K., Martín, Y., Martinez, O., Martucci, M., Masciantonio, G., Mase, K., Mustafa, M., Matev, R., Matthews, J., Mebarki, N., Medina-Tanco, G., Mendoza, M. A., Menshikov, A., Merino, A., Meseguer, J., Meyer, S. S., Mimouni, J., Miyamoto, H., Mizumoto, Y., Monaco, A., Morales de los Ríos, J. A., Nagataki, S., Naitamor, S., Napolitano, T., Nava, R., Neronov, A., Nomoto, K., Nonaka, T., Ogawa, T., Ogio, S., Ohmori, H., Olinto, A. V., Orleański, P., Osteria, G., Pagliaro, A., Painter, W., Panasyuk, M. I., Panico, B., Parizot, E., Park, I. H., Pastircak, B., Patzak, T., Paul, T., Pérez-Grande, I., Perfetto, F., Peter, T., Picozza, P., Pindado, S., Piotrowski, L. W., Piraino, S., Placidi, L., Plebaniak, Z., Pliego, S., Pollini, A., Polonski, Z., Popescu, E. M., Prat, P., Prévôt, G., Prieto, H., Puehlhofer, G., Putis, M., Rabanal, J., Radu, A. A., Reyes, M., Rezazadeh, M., Ricci, M., Rodríguez Frías, M. D., Ronga, F., Roudil, G., Rusinov, I., Rybczyński, M., Sabau, M., Sáez Cano, G., Sagawa, H., Sahnoune, Z., Saito, A., Sakaki, N., Salazar, H., Sanchez Balanzar, J. C., Sánchez, J. L., Santangelo, A., Sanz-Andrés, A., Sanz Palomino, M., Saprykin, O., Sarazin, F., Sato, M., Schanz, T., Schieler, H., Scotti, V., Selmane, S., Semikoz, D., Serra, M., Sharakin, S., Shimizu, H. M., Shin, H. S., Shinozaki, K., Shirahama, T., Sokolsky, P., Spataro, B., Stan, I., Sugiyama, T., Supanitsky, D., Suzuki, M., Szabelska, B., Szabelski, J., Tajima, N., Tajima, T., Takahashi, Y., Takami, H., Takeda, M., Takizawa, Y., Talai, M. C., Tameda, Y., Tenzer, C., Thomas, S. B., Thomson, G. B., Tibolla, O., Tkachev, L., Tokuno, H., Tomida, T., Tone, N., Toscano, S., Traïche, M., Tsenov, R., Tsunesada, Y., Tsuno, K., Tubbs, J., Turriziani, S., Uchihori, Y., Vaduvescu, O., Valdés-Galicia, J. F., Vallania, P., Vankova, G., Vigorito, C., Villaseñor, L., Vlcek, B., von Ballmoos, P., Vrabel, M., Wada, S., Watanabe, J., Watts, J., Weber, M., Weigand Muñoz, R., Weindl, A., Wiencke, L., Wille, M., Wilms, J., Włodarczyk, Z., Yamamoto, T., Yang, J., Yano, H., Yashin, I. V., Yonetoku, D., Yoshida, S., Young, R., Zgura, I. S., Zotov, M. Yu., Zuccaro Marchi, A., Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, and PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)

Subjects
Fresnel lens, Photomultiplier, Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, Night sky, JEM-EUSO, Cosmic ray, Field of view, Astrophysics::Cosmology and Extragalactic Astrophysics, 7. Clean energy, 01 natural sciences, cosmic rays, EAS, UHECR, Astronomy and Astrophysics, Aeronáutica, law.invention, Telescope, law, 0103 physical sciences, Ultra-high-energy cosmic ray, 010303 astronomy & astrophysics, cosmic ray, Astrophysique, Physics, Fresnel len, 010308 nuclear & particles physics, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy, Astronomie, Astronomía, Limiting magnitude, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract

EUSO-TA is a ground-based telescope, installed at the Telescope Array (TA) site in Black Rock Mesa, Utah, USA. This is the first detector to successfully use a Fresnel lens based optical system and multi-anode photomultipliers (64 channels per tube, 2304 channels encompassing a 10.6° × 10.6° field of view) for detection of Ultra High Energy Cosmic Rays (UHECR). The telescope is located in front of one of the fluorescence detectors of the TA experiment. Since its installation in 2013, the detector has observed several ultra-high energy cosmic ray events and, in addition, meteors. The limiting magnitude of 5.5 on summed frames (∼ 3 ms) has been established. Measurements of the UV night sky emission in different conditions and moon phases and positions have been completed. The performed observations serve as a proof of concept for the future application of this detector technology., 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2018

46. The EUSO@Turlab Project: Results from Phase II

Author

A. Youssef, M. Manfrin, R. Mulas, Gregorio Suino, S. Bacholle, G. Contino, R. Forza, N. Guardone, Rossella Caruso, S. Blin, Pierre Barrillon, Miguel Onorato, G. Cotto, A. Jung, J. Rabanal, Guillaume Prévôt, P. Gorodetzky, E. Parizot, Marco Mignone, M. E. Bertaina, S. Dagoret-Campagne, R. Casu, Hiroko Miyamoto, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Organisation de Micro-Électronique Générale Avancée (OMEGA), École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), JEM-EUSO, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), and Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS)

Subjects
020301 aerospace & aeronautics, Brightness, business.industry, Detector, Phase (waves), Cosmic ray, Field of view, 02 engineering and technology, Rotating tank, 01 natural sciences, law.invention, Telescope, 0203 mechanical engineering, law, 0103 physical sciences, Focal surface, Aerospace engineering, business, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], 010303 astronomy & astrophysics
Abstract

International audience; The TurLab facility is a laboratory, equipped with a 5 m diameter and 1 m deep rotating tank,located in the Physics Department of the University of Turin. Originally built mainly to study problems where system rotation plays a key role in the fluid behaviour such as in atmospheric and oceanic flows at different scales, in the past few years the TurLab facility has been used to perform experiments related to observation of Extreme Energy Cosmic Rays from space using the fluo-rescence technique, as in the case of the JEM-EUSO mission, where the diffuse night brightness and artificial light sources can vary significantly in time and space inside the Field of View of the telescope. The description of the EUSO@TurLab project and its first results have been presented in the past. During the last two years many upgrades have been performed on the instrumenta-tion mainly related to the read-out electronics: SPACIROC-1 (employed in EUSO-Balloon and EUSO-TA prototypes) and SPACIROC-3 (EUSO-SPB and Mini-EUSO) which allowed to test a fully equipped Elementary Cell of JEM-EUSO. This phase has been named Phase II. Moreover, the Focal Surface of EUSO-Balloon with the level 1 trigger logic implemented in the Photo-Detector Module has been tested at TurLab after the Canada flight. Finally, tests related to the possibility to employ a EUSO-like detector for other type of applications such as wave monitor-ing and imaging detector have been pursued. The tests and results obtained in EUSO@TurLab Project - Phase II are described.

Published
2017

47. Meteor studies in the framework of the JEM-EUSO program

Author

M. Dupieux, S. Bartocci, T. Shibata, Francesco Isgrò, K. Kudela, J. N. Albert, M. Di Martino, A. Marini, S. Blin-Bondil, Frederic Jean Ronga, Mohammed Bakiri, Thomas Schanz, O. Larsson, B. Mot, Silvia Ferrarese, T. Djemil, Alberto Cellino, Livio Conti, K. Martens, G. Osteria, T. Tymieniecka, J. Sledd, G. Cordero, L. R. Wiencke, A. Zuccaro Marchi, G. Roudil, Jörn Wilms, M. Rybczyński, R. Bechini, Patrick J. Reardon, M. Haiduc, Lech Wiktor Piotrowski, Yukihiro Takahashi, José Luis Sánchez, R. Young, O. A. Saprykin, Sug Whan Kim, Y. Karadzhov, M. Nagano, Toshiki Tajima, H. Khales, B. Harlov, Carlo Vigorito, G. Sáez Cano, M. Sakata, Massimiliano Bonamente, A. Belov, T. Shirahama, Marco Casolino, G. Siemieniec-Oziȩbło, Hitoshi Ohmori, Yoshiya Kawasaki, Andreas A. Berlind, Alfonso Monaco, W. Hidber, Claudio Fornaro, Takuji Nakamura, E. Kuznetsov, F. Kanouni, Jianyi Yang, K. Benmessai, Katsuaki Asano, Yoshitaka Itow, Shigeto Watanabe, O. Martinez, J. Błȩcki, Tokonatsu Yamamoto, E. Bozzo, D. Allard, Barbara Szabelska, C. González Alvarado, J. Geary, Mikhail Panasyuk, Shinsuke Abe, Alexander Kusenko, E. M. Popescu, Hajime Yano, S. Yoshida, J. Szabelski, T. Peter, Gustavo Alonso, G. Castellini, M. E. Bertaina, M. Ave Pernas, R. Matev, J. Fujimoto, C. De Santis, Sebastián Franchini, Piotr Orleanski, H. Lim, M. D. Rodríguez Frías, N. Tajima, M. Takeda, Shigehiro Nagataki, A. Neronov, M. C. Maccarone, H. Miyamoto, Ken'ichi Nomoto, F. Dulucq, L. Santiago Crúz, M. Fouka, L. Caramete, M. Suzuki, W. Aouimeur, Amine Ahriche, M. Sanz Palomino, J. F. Valdés-Galicia, L. G. Tkachev, H. Tahi, Satoshi Wada, T. Ogawa, M. C. Talai, K. Słomińska, Markus Roth, K. Shinozaki, Angela V. Olinto, Z. Plebaniak, D. Kolev, M. Flamini, F. Bisconti, L. Mehrad, Michiyuki Chikawa, F. Tajima, A. Kedadra, S. Csorna, G. Vankova, J. Fernández-Soriano, Andrea Santangelo, Gali Garipov, Y. Takizawa, P. L. Biermann, S. Bacholle, D. Maravilla, Humberto Ibarguen Salazar, Valerie Connaughton, R. Guehaz, R. Attallah, P. Gorodetzky, Giuseppe Giraudo, T. Paul, A. Ebersoldt, S. Biktemerova, I. Dutan, Nicusor Arsene, A. Acheli, Piero Vallania, H. Tokuno, Ralph Engel, Fausto Guarino, A. Guzmán, C. Lachaud, I. Rusinov, Toshiyuki Nonaka, B. Vlcek, M. D. Sabau, L. Placidi, M. Wille, A. Sobey, Y. Uchihori, J. Hernández Carretero, A. Nardelli, H. Prieto, M. Kleifges, M. Unger, S. Dagoret-Campagne, C. De Donato, R. Cremonini, P. von Ballmoos, M. Ricci, M. Perdichizzi, Soon-Wook Kim, John N. Matthews, L. Villaseñor, H. Ikeda, Francesco Fenu, Naoto Sakaki, Yoshihiko Mizumoto, G. Masciantonio, Z. Włodarczyk, R. Tsenov, D. Monnier-Ragaigne, A. Segreto, Javier Licandro, Sergio Fernández-González, L. López Campano, Toshitaka Kajino, Belkacem Benadda, Tomás Belenguer, K. Higashide, C. Moretto, P. Galeotti, Valentina Scotti, M. Traïche, G. Medina-Tanco, Marcos Reyes, A. Pollini, Pavel Klimov, B. Panico, Takayuki Tomida, J. Bayer, J. Jochum, Graciela B. Gelmini, N. Blanc, H. Attoui, C. Tenzer, T. Sugiyama, Hajime Takami, H. J. Crawford, J. Karczmarczyk, Tadeusz Wibig, Masaki Fukushima, G. Chiritoi, J. L. Marcos, M. Mahdi, Y. Hachisu, F. Perfetto, A. Jung, F. Cafagna, G. Modestino, Y. Arai, C. de la Taille, T. Pierog, E. Joven, K. Katahira, J. Watanabe, N. Inoue, L. del Peral, A. Franceschi, E. Parizot, Pavol Bobik, D. Kang, D. Ikeda, Isabel Pérez-Grande, Johannes Eser, Y. Yamamoto, M. Rahmani, H. Lahmar, Osvaldo Catalano, B. Pastirčák, Simona Toscano, F. Sarazin, M. Serra, Luis A. Anchordoqui, T. Batsch, Jeong Sook Kim, N. Tone, Daisuke Yonetoku, Marc Weber, J. A. Morales de los Ríos, G. Abdellaoui, Pierre Barrillon, I. Kaneko, P. Baragatti, Ovidiu Vaduvescu, Santiago Pindado, B. A. Khrenov, Eduardo García-Ortega, Estíbaliz Gascón, M. Lacombe, Guillaume Prévôt, Hanna Rothkaehl, M. Yu. Zotov, R. Nava, Piergiorgio Picozza, Sergei A. Sharakin, N. Mebarki, Susumu Inoue, A. Haungs, S. Piraino, Claudio Cassardo, W. Painter, J. Rabanal, Dmitri Semikoz, B. Nadji, J. Mimouni, M. A. Mendoza, D. Campana, I. S. Zgura, Rossella Caruso, F. Lakhdari, M. Bogomilov, V. S. Morozenko, I. V. Yashin, M. Nagata, Inkyu Park, L. Marcelli, M. Putis, Y. Miyazaki, A. Weindl, Andrés Merino, A. Bruno, Yoshimasa Kurihara, J. C. Sanchez, H. Schieler, J. Lee, Antonella Castellina, Mitsuteru Sato, Mark Christl, F. Kajino, T. Jammer, O. Tibolla, Michael S. Briggs, Dmitry V. Naumov, P. Carlson, T. Mernik, T. Patzak, T. Murakami, J.N. Capdevielle, H. W. Park, Francesca Capel, S. Pliego, Thomas J. Weiler, S. Mackovjak, D. Supanitsky, R. Weigand Muñoz, Shoichi Ogio, I. Stan, K. Kawai, Akinori Saito, A. Caramete, K. S. Caballero, Hiroyuki Sagawa, A. Radu, Maxim Gonchar, Hirohiko M. Shimizu, S. A. Djenas, S. Kalli, J. Watts, C. Pennypacker, M. Vrabel, P. Prat, Z. Sahnoune, M. Karus, Domenico Finco, Roberto Bellotti, K. Mase, James H. Adams, H. Sato, Octavian Micu, E. G. Judd, Katsuhiko Tsuno, I. Kreykenbohm, Vladimir Andreev, Y. Martín, S. Ahmad, A. Anzalone, T. Napolitano, Christer Fuglesang, José Meseguer, Angel Sanz-Andrés, Y. Tsunesada, J. Genci, K. Belov, C. Catalano, M. Rezazadeh, S. Selmane, Toshikazu Ebisuzaki, S. Messaoud, Ke Fang, R. Boudaoud, Abdellaoui, G., Abe, S., Acheli, A., Adams, J. H., Ahmad, S., Ahriche, A., Albert, J. N., Allard, D., Alonso, G., Anchordoqui, L., Andreev, V., Anzalone, A., Aouimeur, W., Arai, Y., Arsene, N., Asano, K., Attallah, R., Attoui, H., Ave Pernas, M., Bacholle, S., Bakiri, M., Baragatti, P., Barrillon, P., Bartocci, S., Batsch, T., Bayer, J., Bechini, R., Belenguer, T., Bellotti, R., Belov, A., Belov, K., Benadda, B., Benmessai, K., Berlind, A. A., Bertaina, M., Biermann, P. L., Biktemerova, S., Bisconti, F., Blanc, N., Błȩcki, J., Blin Bondil, S., Bobik, P., Bogomilov, M., Bonamente, M., Boudaoud, R., Bozzo, E., Briggs, M. S., Bruno, A., Caballero, K. S., Cafagna, F., Campana, D., Capdevielle, J. N., Capel, F., Caramete, A., Caramete, L., Carlson, P., Caruso, R., Casolino, M., Cassardo, C., Castellina, A., Castellini, G., Catalano, C., Catalano, O., Cellino, A., Chikawa, M., Chiritoi, G., Christl, M. J., Connaughton, V., Conti, L., Cordero, G., Crawford, H. J., Cremonini, R., Csorna, S., Dagoret Campagne, S., De Donato, C., de la Taille, C., De Santis, C., del Peral, L., Di Martino, M., Djemil, T., Djenas, S. A., Dulucq, F., Dupieux, M., Dutan, I., Ebersoldt, A., Ebisuzaki, T., Engel, R., Eser, J., Fang, K., Fenu, F., Fernández González, S., Fernández Soriano, J., Ferrarese, S., Finco, D., Flamini, M., Fornaro, C., Fouka, M., Franceschi, A., Franchini, S., Fuglesang, C., Fujimoto, J., Fukushima, M., Galeotti, P., García Ortega, E., Garipov, G., Gascón, E., Geary, J., Gelmini, G., Genci, J., Giraudo, G., Gonchar, M., González Alvarado, C., Gorodetzky, P., Guarino, Fausto, Guehaz, R., Guzmán, A., Hachisu, Y., Haiduc, M., Harlov, B., Haungs, A., Hernández Carretero, J., Hidber, W., Higashide, K., Ikeda, D., Ikeda, H., Inoue, N., Inoue, S., Isgro', Francesco, Itow, Y., Jammer, T., Joven, E., Judd, E. G., Jung, A., Jochum, J., Kajino, F., Kajino, T., Kalli, S., Kaneko, I., Kang, D., Kanouni, F., Karadzhov, Y., Karczmarczyk, J., Karus, M., Katahira, K., Kawai, K., Kawasaki, Y., Kedadra, A., Khales, H., Khrenov, B. A., Kim, Jeong Sook, Kim, Soon Wook, Kim, Sug Whan, Kleifges, M., Klimov, P. A., Kolev, D., Kreykenbohm, I., Kudela, K., Kurihara, Y., Kusenko, A., Kuznetsov, E., Lacombe, M., Lachaud, C., Lahmar, H., Lakhdari, F., Larsson, O., Lee, J., Licandro, J., Lim, H., López Campano, L., Maccarone, M. C., Mackovjak, S., Mahdi, M., Maravilla, D., Marcelli, L., Marcos, J. L., Marini, A., Martens, K., Martín, Y., Martinez, O., Masciantonio, G., Mase, K., Matev, R., Matthews, J. N., Mebarki, N., Medina Tanco, G., Mehrad, L., Mendoza, M. A., Merino, A., Mernik, T., Meseguer, J., Messaoud, S., Micu, O., Mimouni, J., Miyamoto, H., Miyazaki, Y., Mizumoto, Y., Modestino, G., Monaco, A., Monnier Ragaigne, D., Morales de los Ríos, J. A., Moretto, C., Morozenko, V. S., Mot, B., Murakami, T., Nadji, B., Nagano, M., Nagata, M., Nagataki, S., Nakamura, T., Napolitano, T., Nardelli, A., Naumov, D., Nava, R., Neronov, A., Nomoto, K., Nonaka, T., Ogawa, T., Ogio, S., Ohmori, H., Olinto, A. V., Orleański, P., Osteria, G., Painter, W., Panasyuk, M. I., Panico, B., Parizot, E., Park, I. H., Park, H. W., Pastircak, B., Patzak, T., Paul, T., Pennypacker, C., Perdichizzi, M., Pérez Grande, I., Perfetto, Francesco, Peter, T., Picozza, P., Pierog, T., Pindado, S., Piotrowski, L. W., Piraino, S., Placidi, L., Plebaniak, Z., Pliego, S., Pollini, A., Popescu, E. M., Prat, P., Prévôt, G., Prieto, H., Putis, M., Rabanal, J., Radu, A. A., Rahmani, M., Reardon, P., Reyes, M., Rezazadeh, M., Ricci, M., Rodríguez Frías, M. D., Ronga, F., Roth, M., Rothkaehl, H., Roudil, G., Rusinov, I., Rybczyński, M., Sabau, M. D., Sáez Cano, G., Sagawa, H., Sahnoune, Z., Saito, A., Sakaki, N., Sakata, M., Salazar, H., Sanchez, J. C., Sánchez, J. L., Santangelo, A., Santiago Crúz, L., Sanz Andrés, A., Sanz Palomino, M., Saprykin, O., Sarazin, F., Sato, H., Sato, M., Schanz, T., Schieler, H., Scotti, Valentina, Segreto, A., Selmane, S., Semikoz, D., Serra, M., Sharakin, S., Shibata, T., Shimizu, H. M., Shinozaki, K., Shirahama, T., Siemieniec Oziȩbło, G., Sledd, J., Słomińska, K., Sobey, A., Stan, I., Sugiyama, T., Supanitsky, D., Suzuki, M., Szabelska, B., Szabelski, J., Tahi, H., Tajima, F., Tajima, N., Tajima, T., Takahashi, Y., Takami, H., Takeda, M., Takizawa, Y., Talai, M. C., Tenzer, C., Tibolla, O., Tkachev, L., Tokuno, H., Tomida, T., Tone, N., Toscano, S., Traïche, M., Tsenov, R., Tsunesada, Y., Tsuno, K., Tymieniecka, T., Uchihori, Y., Unger, M., Vaduvescu, O., Valdés Galicia, J. F., Vallania, P., Vankova, G., Vigorito, C., Villaseñor, L., Vlcek, B., von Ballmoos, P., Vrabel, M., Wada, S., Watanabe, J., Watanabe, S., Null, J. Watts J. r., Weber, M., Weigand Muñoz, R., Weindl, A., Weiler, T. J., Wibig, T., Wiencke, L., Wille, M., Wilms, J., Włodarczyk, Z., Yamamoto, T., Yamamoto, Y., Yang, J., Yano, H., Yashin, I. V., Yonetoku, D., Yoshida, S., Young, R., Zgura, I. S, Zotov, M. Y. u., and Zuccaro Marchi, A.

Subjects
Physics, Meteor (satellite), Mini-EUSO, 010504 meteorology & atmospheric sciences, Meteors, JEM-EUSO, EUSO-TA, Astronomy, Nuclearites, Astronomy and Astrophysics, 01 natural sciences, Preliminary analysis, Aeronáutica, Space and Planetary Science, 0103 physical sciences, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences, Remote sensing
Abstract

著者人数: 360名 (JAXA職員: 池田, 博一 ; 鈴木, 睦 ; 矢野, 創), Accepted: 2016-12-08, 資料番号: SA1170070000

Published
2017

48. Cosmic ray oriented performance studies for the JEM-EUSO first level trigger

Author

H. Sato, T. Djemil, Alberto Cellino, Octavian Micu, Javier Licandro, M. D. Rodríguez Frías, Z. Plebaniak, N. Guardone, Katsuhiko Tsuno, A. Belov, L. R. Wiencke, N. Tone, G. Cordero, A. Anzalone, T. Napolitano, Michiyuki Chikawa, Katsuaki Asano, A. Ebersoldt, Daisuke Yonetoku, I. S. Zgura, Roberto Bellotti, M. Mahdi, T. Pierog, Yoshimasa Kurihara, H. Schieler, E. M. Popescu, Antonella Castellina, Mitsuteru Sato, T. Jammer, K. S. Caballero, Hiroyuki Sagawa, Christer Fuglesang, J. Watanabe, G. Roudil, K. Mase, Graciela B. Gelmini, G. Chiritoi, Y. Hachisu, F. Perfetto, Y. Yamamoto, B. Pastirčák, J. Geary, H. Khales, José Meseguer, Angel Sanz-Andrés, Osvaldo Catalano, Santiago Pindado, Junpei Fujimoto, B. A. Khrenov, S. Pliego, Thomas J. Weiler, Pierre Barrillon, Eduardo García-Ortega, Sergei A. Sharakin, Massimiliano Bonamente, James H. Adams, Y. Tsunesada, H. Lahmar, Patrick J. Reardon, Toshiki Tajima, G. Siemieniec-Oziȩbło, Satoshi Wada, T. Ogawa, M. Yu. Zotov, J. Genci, Piergiorgio Picozza, N. Mebarki, Mohammed Bakiri, C. Catalano, K. Benmessai, M. Suzuki, Valentina Scotti, Hitoshi Ohmori, G. Abdellaoui, Francesco Isgrò, Daisuke Ikeda, Belkacem Benadda, W. Painter, P. Gorodetzky, Yoshiya Kawasaki, E. Kuznetsov, Yoshihiko Mizumoto, R. Bechini, M. C. Talai, C. De La Taille, K. Shinozaki, A. Radu, F.J. Ronga, Alfonso Monaco, Shinsuke Abe, B. Nadji, E. Parizot, A. Guzmán, Toshitaka Kajino, K. Kawai, Ralph Engel, I. Kreykenbohm, Hajime Takami, Angela V. Olinto, Andrea Santangelo, D. Maravilla, S. Blin-Bondil, D. Allard, Vladimir Andreev, Masaki Fukushima, R. Nava, V. S. Morozenko, Akinori Saito, Maxim Gonchar, Hirohiko M. Shimizu, M. A. Mendoza, E. G. Judd, D. Kang, G. Castellini, Andreas A. Berlind, M. Rezazadeh, S. Selmane, Alexander Kusenko, K. Higashide, C. Moretto, P. Galeotti, Y. Martín, M. E. Bertaina, L. Villaseñor, C. De Santis, J. Yang, Rossella Caruso, J. Karczmarczyk, Shigeto Watanabe, Ken'ichi Nomoto, K. Słomińska, H. Attoui, C. Tenzer, F Dulucq, N. Inoue, S. Bacholle, John N. Matthews, Francesca Capel, J. F. Valdés-Galicia, L. G. Tkachev, H. Tahi, G. Vankova, Tokonatsu Yamamoto, Guillaume Prévôt, L. del Peral, A. Franceschi, Pavol Bobik, T. Sugiyama, Hajime Yano, Tadeusz Wibig, B. Mot, S. Dagoret-Campagne, S. Bartocci, E. Bozzo, M. Serra, Luis A. Anchordoqui, T. Shibata, M. Traïche, S. Mackovjak, J. Fernández-Soriano, D. Supanitsky, T. Batsch, Toshio Murakami, R. Young, M. Sakata, S. Biktemerova, Toshikazu Ebisuzaki, Yukihiro Takahashi, José Luis Sánchez, S. Ahmad, C. Lachaud, F. Cafagna, H. J. Crawford, O. Larsson, S. Messaoud, K. Kudela, G. Modestino, E. Joven, M. Rahmani, Giuseppe Giraudo, R. Weigand Muñoz, T. Shirahama, S. A. Djenas, S. Kalli, I. Kaneko, A. Haungs, S. Piraino, J. Watts, Hanna Rothkaehl, J. Mimouni, J. A. Morales de los Ríos, Toshiyuki Nonaka, Ovidiu Vaduvescu, M. Karus, L. Santiago Crúz, M. Bogomilov, Josef Jochum, F. Bisconti, M. Lacombe, Claudio Cassardo, Shoichi Ogio, M. Flamini, Silvia Ferrarese, C. Pennypacker, Marco Casolino, Claudio Fornaro, Susumu Inoue, Tomás Belenguer, J. Błȩcki, L. Mehrad, M. Vrabel, P. Prat, Piotr Orleanski, Ke Fang, Mikhail Panasyuk, F. Kajino, Andrés Merino, Y. Takizawa, M. Fouka, P. L. Biermann, Z. Sahnoune, D. Kolev, H. Lim, J. C. Sanchez, Maciej Rybczyński, G. Sáez Cano, D. Monnier-Ragaigne, A. Segreto, W. Aouimeur, A. Neronov, M. C. Maccarone, B. Harlov, I. Rusinov, P. Carlson, T. Mernik, A. Jung, H. W. Park, R. Boudaoud, M. Dupieux, I. V. Yashin, Carlo Vigorito, Domenico Finco, A. Kedadra, T. Paul, Valerie Connaughton, Marcos Reyes, R. Guehaz, N. Blanc, M. Ave Pernas, T. Nakamura, Yoshio Arai, L. Marcelli, I. Dutan, L. Placidi, A. Sobey, Francesco Fenu, Piero Vallania, S. E. Csorna, G. Masciantonio, G. Medina-Tanco, J. L. Marcos, M. D. Sabau, Johannes Eser, H. Prieto, R. Cremonini, H. Ikeda, Naoto Sakaki, G. Cotto, Markus Roth, C. De Donato, L. López Campano, Sergio Fernández-González, Takayuki Tomida, Nicusor Arsene, J. Bayer, A. Insolia, M. Kleifges, N. Tajima, M. Takeda, Soon-Wook Kim, J. Rabanal, J. Hernández Carretero, Fausto Guarino, P. von Ballmoos, M. Ricci, A. Bruno, M. Unger, Shigehiro Nagataki, K. Katahira, Isabel Pérez-Grande, F. Sarazin, Zbigniew Wlodarczyk, Marc Weber, R. Matev, Simona Toscano, Michael S. Briggs, M. Haiduc, Lech Wiktor Piotrowski, S. Yoshida, J. Szabelski, Estíbaliz Gascón, O. Martinez, T. Patzak, M. Nagata, Dmitry V. Naumov, J.N. Capdevielle, I. Stan, A. Caramete, K. Martens, Konstantin Belov, Joowon Lee, F. Tajima, A. Acheli, J. N. Albert, Thomas Schanz, M. Wille, Livio Conti, Y. Uchihori, A. Zuccaro Marchi, Jörn Wilms, O. A. Saprykin, Sug Whan Kim, F. Kanouni, Sebastián Franchini, Gali Garipov, R. Attallah, D. Campana, F. Lakhdari, Barbara Szabelska, Inkyu Park, M. Putis, Y. Miyazaki, A. Weindl, T. Peter, B. Vlcek, Mark Christl, Gustavo Alonso, O. Tibolla, Jeong Sook Kim, C. González Alvarado, P. Baragatti, H. Miyamoto, M. Manfrin, Yoshitaka Itow, L. Caramete, M. Sanz Palomino, Y. Karadzhov, Amine Ahriche, Humberto Ibarguen Salazar, G. Contino, H. Tokuno, W. Hidber, R. Tsenov, R. Forza, A. Pollini, Pavel Klimov, B. Panico, M. Mignone, M. Di Martino, A. Marini, G. Osteria, D.V. Semikoz, T. Tymieniecka, J. Sledd, M. Nagano, Abdellaoui, G., Abe, S., Acheli, A., Adams, J. H., Ahmad, S., Ahriche, A., Albert, J. N., Allard, D., Alonso, G., Anchordoqui, L., Andreev, V., Anzalone, A., Aouimeur, W., Arai, Y., Arsene, N., Asano, K., Attallah, R., Attoui, H., Ave pernas, M., Bacholle, S., Bakiri, M., Baragatti, P., Barrillon, P., Bartocci, S., Batsch, T., Bayer, J., Bechini, R., Belenguer, T., Bellotti, R., Belov, A., Belov, K., Benadda, B., Benmessai, K., Berlind, A. A., Bertaina, M., Biermann, P. L., Biktemerova, S., Bisconti, F., Blanc, N., Błȩcki, J., Blin Bondil, S., Bobik, P., Bogomilov, M., Bonamente, M., Boudaoud, R., Bozzo, E., Briggs, M. S., Bruno, A., Caballero, K. S., Cafagna, F., Campana, D., Capdevielle, J. N., Capel, F., Caramete, A., Caramete, L., Carlson, P., Caruso, R., Casolino, M., Cassardo, C., Castellina, A., Castellini, G., Catalano, C., Catalano, O., Cellino, A., Chikawa, M., Chiritoi, G., Christl, M. J., Connaughton, V., Conti, L., Contino, G., Cordero, G., Cotto, G., Crawford, H. J., Cremonini, R., Csorna, S., Dagoret Campagne, S., De donato, C., De la taille, C., De santis, C., Del peral, L., Di martino, M., Djemil, T., Djenas, S. A., Dulucq, F., Dupieux, M., Dutan, I., Ebersoldt, A., Ebisuzaki, T., Engel, R., Eser, J., Fang, K., Fenu, F., Fernández González, S., Fernández Soriano, J., Ferrarese, S., Finco, D., Flamini, M., Fornaro, C., Forza, R., Fouka, M., Franceschi, A., Franchini, S., Fuglesang, C., Fujimoto, J., Fukushima, M., Galeotti, P., García Ortega, E., Garipov, G., Gascón, E., Geary, J., Gelmini, G., Genci, J., Giraudo, G., Gonchar, M., González alvarado, C., Gorodetzky, P., Guardone, N., Guarino, Fausto, Guehaz, R., Guzmán, A., Hachisu, Y., Haiduc, M., Harlov, B., Haungs, A., Hernández carretero, J., Hidber, W., Higashide, K., Ikeda, D., Ikeda, H., Inoue, N., Inoue, S., Insolia, A., Isgro', Francesco, Itow, Y., Jammer, T., Joven, E., Judd, E. G., Jung, A., Jochum, J., Kajino, F., Kajino, T., Kalli, S., Kaneko, I., Kang, D., Kanouni, F., Karadzhov, Y., Karczmarczyk, J., Karus, M., Katahira, K., Kawai, K., Kawasaki, Y., Kedadra, A., Khales, H., Khrenov, B. A., Kim, Jeong Sook, Kim, Soon Wook, Kim, Sug Whan, Kleifges, M., Klimov, P. A., Kolev, D., Kreykenbohm, I., Kudela, K., Kurihara, Y., Kusenko, A., Kuznetsov, E., Lacombe, M., Lachaud, C., Lahmar, H., Lakhdari, F., Larsson, O., Lee, J., Licandro, J., Lim, H., López campano, L., Maccarone, M. C., Mackovjak, S., Mahdi, M., Manfrin, M., Maravilla, D., Marcelli, L., Marcos, J. L., Marini, A., Martens, K., Martín, Y., Martinez, O., Masciantonio, G., Mase, K., Matev, R., Matthews, J. N., Mebarki, N., Medina Tanco, G., Mehrad, L., Mendoza, M. A., Merino, A., Mernik, T., Meseguer, J., Messaoud, S., Micu, O., Mignone, M., Mimouni, J., Miyamoto, H., Miyazaki, Y., Mizumoto, Y., Modestino, G., Monaco, A., Monnier Ragaigne, D., Morales de los ríos, J. A., Moretto, C., Morozenko, V. S., Mot, B., Murakami, T., Nadji, B., Nagano, M., Nagata, M., Nagataki, S., Nakamura, T., Napolitano, T., Naumov, D., Nava, R., Neronov, A., Nomoto, K., Nonaka, T., Ogawa, T., Ogio, S., Ohmori, H., Olinto, A. V., Orleański, P., Osteria, G., Painter, W., Panasyuk, M. I., Panico, B., Parizot, E., Park, I. H., Park, H. W., Pastircak, B., Patzak, T., Paul, T., Pennypacker, C., Pérez Grande, I., Perfetto, Francesco, Peter, T., Picozza, P., Pierog, T., Pindado, S., Piotrowski, L. W., Piraino, S., Placidi, L., Plebaniak, Z., Pliego, S., Pollini, A., Popescu, E. M., Prat, P., Prévôt, G., Prieto, H., Putis, M., Rabanal, J., Radu, A. A., Rahmani, M., Reardon, P., Reyes, M., Rezazadeh, M., Ricci, M., Rodríguez frías, M. D., Ronga, F., Roth, M., Rothkaehl, H., Roudil, G., Rusinov, I., Rybczyński, M., Sabau, M. D., Sáez cano, G., Sagawa, H., Sahnoune, Z., Saito, A., Sakaki, N., Sakata, M., Salazar, H., Sanchez, J. C., Sánchez, J. L., Santangelo, A., Santiago crúz, L., Sanz Andrés, A., Sanz palomino, M., Saprykin, O., Sarazin, F., Sato, H., Sato, M., Schanz, T., Schieler, H., Scotti, Valentina, Segreto, A., Selmane, S., Semikoz, D., Serra, M., Sharakin, S., Shibata, T., Shimizu, H. M., Shinozaki, K., Shirahama, T., Siemieniec Oziȩbło, G., Sledd, J., Słomińska, K., Sobey, A., Stan, I., Sugiyama, T., Supanitsky, D., Suzuki, M., Szabelska, B., Szabelski, J., Tahi, H., Tajima, F., Tajima, N., Tajima, T., Takahashi, Y., Takami, H., Takeda, M., Takizawa, Y., Talai, M. C., Tenzer, C., Tibolla, O., Tkachev, L., Tokuno, H., Tomida, T., Tone, N., Toscano, S., Traïche, M., Tsenov, R., Tsunesada, Y., Tsuno, K., Tymieniecka, T., Uchihori, Y., Unger, M., Vaduvescu, O., Valdés Galicia, J. F., Vallania, P., Vankova, G., Vigorito, C., Villaseñor, L., Vlcek, B., Von ballmoos, P., Vrabel, M., Wada, S., Watanabe, J., Watanabe, S., Watts, J., Weber, M., Weigand muñoz, R., Weindl, A., Weiler, T. J., Wibig, T., Wiencke, L., Wille, M., Wilms, J., Włodarczyk, Z., Yamamoto, T., Yamamoto, Y., Yang, J., Yano, H., Yashin, I. V., Yonetoku, D., Yoshida, S., Young, R., Zgura, I. S., Zotov, M. Y. u., Zuccaro marchi, A., Laboratoire Leprince-Ringuet (LLR), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, and PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)

Subjects
Nuclear and High Energy Physics, data analysis method, Instrumentation, Astrophysics::High Energy Astrophysical Phenomena, Night sky, measurement methods, satellite, JEM-EUSO, FPGA, Nightglow background, Trigger system, Cosmic ray, 01 natural sciences, law.invention, Aeronáutica, Telescope, nightglow background, law, 0103 physical sciences, International Space Station, cosmic radiation: UHE, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010303 astronomy & astrophysics, background: suppression, Remote sensing, Physics, detector: wide-angle, trigger system, laser: pulsed, showers: atmosphere, 010308 nuclear & particles physics, Astrophysics::Instrumentation and Methods for Astrophysics, trigger, Astronomía, Satellite, background: fluctuation, FPGA, JEM-EUSO, Nightglow background, Trigger system, Nuclear and High Energy Physics, Instrumentation, Neutrino, Energy (signal processing), performance
Abstract

著者人数: 368名 (JAXA職員: 池田, 博一 ; 鈴木, 睦 ; 矢野, 創), Accepted: 2017-05-29, 資料番号: SA1170117000

Published
2017

49. Astrophysical interpretation of Pierre Auger Observatory measurements of the UHECR energy spectrum and mass composition

Author

R. Conceição, Miroslav Hrabovský, A. Haungs, J. L. Harton, S. G. Blaess, P. Mantsch, Z. Szadkowski, Carola Dobrigkeit, M. Plum, M. E. Bertaina, Alan Watson, Mihai Niculescu-Oglinzanu, J. Alvarez Castillo, F. Diogo, M. Zavrtanik, R. M. de Almeida, D. Reinert, Stijn Buitink, Andrea Chiavassa, M. Malacari, C. Scarso, P. Heimann, Andrej Filipcic, M. Suarez Durán, L. Lopes, E. Kemp, Serguei Vorobiov, L. Molina-Bueno, D. Melo, D. Nitz, M. Settimo, Hernan Wahlberg, David Walz, O. A. Taborda, R. Squartini, R. R. Prado, D. Pakk Selmi-Dei, Petr Schovanek, M. T. Dova, Radomir Smida, J.E. Swain, R. Sato, G. Torralba Elipe, E.M. Holt, L. R. Wiencke, R. Krause, P. Ristori, O. Kambeitz, A. Saleh, M. Gómez Berisso, R. C. Shellard, Ph. Lebrun, Denis Stanca, Olivier Ravel, S. Jansen, A. Fuster, M. Trini, Alejandro Almela, G. Cataldi, E. Varela, J.D. Sanabria Gomez, L. Valore, P.H. Nguyen, E. Mayotte, M. Ambrosio, V. Scherini, A. Śmiałkowski, Philipp Papenbreer, G. Medina-Tanco, David Wittkowski, A. C. Rovero, Lili Yang, G. van Aar, Alexandra Saftoiu, J.R. Hörandel, Mario Buscemi, Sarka Wykes, Stefan Müller, Alexandru Balaceanu, I. Jandt, Ana Martina Botti, Manuela Mallamaci, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, Piotr Homola, R. Ramos-Pollant, Carla Aramo, Vincenzo Rizi, D. Martello, Ralf Ulrich, A. Bridgeman, Muller, B. Caccianiga, I. Allekotte, M. Ziolkowski, Silvia Mollerach, W. R. de Carvalho, O. Martínez Bravo, C. J. Todero Peixoto, J. J. Beatty, Paul Sommers, L. Ochilo, I. A. Minaya, B. Keilhauer, S. J. Saffi, B. Vargas Cárdenas, T. Suomijärvi, Marco Giammarchi, A. Blanco, R. Piegaia, N. Fazzini, N. Krohm, P. Gouffon, B. Sarkar, Christian Glaser, S. J. Sciutto, Dusan Mandat, J. Pallotta, E. J. Quel, M. J. Cooper, A. Insolia, M. Kleifges, D. Zavrtanik, Tobias Winchen, Julien Aublin, Karen S. Caballero-Mora, Octavian Fratu, H. Martinez, Bruce Rafael Mellado Garcia, C. Medina, Miroslav Pech, J. Chudoba, R.C. dos Anjos, J. Espadanal, J. Pȩkala, H. Wilczyński, Markus Lauscher, J. Phuntsok, Markus Roth, H. J. Mathes, Pavel Horvath, L. del Peral, D. LaHurd, M. Palatka, Günter Sigl, G. De Mauro, Martin Erdmann, I. Valiño, Gioacchino Alex Anastasi, Andrej Dundovic, Lorenzo Caccianiga, Maria Rita Coluccia, V. M. Theodoro, Roger W Clay, I. Lhenry-Yvon, Stefano D'Amico, M. I. Micheletti, G. Matthiae, A. N. Yushkov, Antonio Bueno, M. Josebachuili, J. Neuser, Johannes Schulz, R. Engel, K.-H. Becker, M. Pimenta, G. S. Varner, B. Mitrica, Heino Falcke, Sofia Andringa, Valerio Verzi, J. Hulsman, J. Vicha, A. Valbuena-Delgado, Lenka Tomankova, Dariusz Glas, J. Rodriguez Rojo, A. Tepe, Florian Lukas Briechle, A. G. Chavez, Gualberto Avila, Brian Fick, Enrique Zas, Jose Chinellato, B. Tome, Benedikt Zimmermann, Luca Latronico, Pascal Lautridou, A. C. Fauth, Angela V. Olinto, A. Letessier-Selvon, Lorenzo Cazon, C. Di Giulio, Fernando Contreras, Darko Veberic, Alberto Filevich, Bruno Daniel, Carla Bonifazi, Jose A. Bellido, A. van Vliet, Foteini Oikonomou, J. J. Masías Meza, T. Paul, R. Pelayo, G. Salina, Olivier Deligny, S. Querchfeld, S. Sonntag, Francesco Strafella, J. A. Matthews, Jaime Rosado, Ugo Giaccari, R. Cester, A. Cancio, Ioana Codrina Maris, Nicusor Arsene, P. Privitera, A. Tapia, F. Guarino, Peter Buchholz, Jesús Peña-Rodríguez, Ricardo Vázquez, G. C. Hill, Takahiro Fujii, I.M. Brancus, H. Gemmeke, M. Unger, A. Dorofeev, J. Ridky, Igor Katkov, H. Glass, Marco Aglietta, L. Villaseñor, Lukas Middendorf, Christine Peters, G. Rodriguez Fernandez, Daniela Mockler, J. W. Cronin, P. van Bodegom, Nataliia Borodai, S. J. De Jong, Gregory R. Snow, Pierre Billoir, J. R. T. de Mello Neto, Xavier Bertou, A. Zepeda, Pedro Assis, A. Etchegoyen, A. Gorgi, L. Perrone, D. Torres Machado, D. Nosek, A.M. van den Berg, Thomas Harrison, P. Pieroni, F. Arqueros, A. Weindl, H. Nožka, M. Schauer, G. Kukec Mezek, P. H. Hansen, Carla Bleve, Belén Andrada, G. Golup, N. Kunka, D. Heck, D. Yelos, Peter Gorham, M. L. Díaz Castro, L. Collica, Martina Bohacova, Patrick Allison, G. Farrar, C. Hojvat, Jan Ebr, A. Menshikov, Luis A. Anchordoqui, J. Sorokin, L.A.S. Pereira, A. Di Matteo, Francesca Zuccarello, Petr Travnicek, Rodríguez-Frías, Alan Coleman, Raul Sarmento, Trent D. Grubb, H.O. Klages, B. Wundheiler, R. Rebolo Lopez, P. H. Kasper, Juan Manuel Figueira, Frank G. Schröder, Marco Torri, Roberta Colalillo, A. G. Mariazzi, S. Messina, V. Novotny, Rossella Caruso, A. Lucero, S. Mathys, M. Erfani, J. Kleinfeller, A. Tonachini, Daniel Kuempel, Carlos Escobar, P.F. Gómez Vitale, P. Abreu, D. Ravignani, C. J.W.P. Timmermans, Ivone F. M. Albuquerque, Ke Fang, Marcus Niechciol, A.D. Supanitsky, Sutherland, R. M. Kieckhafer, J. Rautenberg, Kai Daumiller, O. Wainberg, Richard Dallier, Francisco Pedreira, Thomas Bretz, Corbin Covault, Matías Rolf Hampel, S. Navas, Lino Miramonti, Joshua A. Gordon, Gaia Silli, F. Sanchez, F. Sarazin, K. H. Kampert, S. Petrera, Leigui de Oliveira, J. F. Valdés Galicia, A. Hervé, B. Revenu, I. De Mitri, J. R. Vázquez, M. Platino, T. Huege, Hernán Gonzalo Asorey, A. Parra, P. Sanchez-Lucas, D. Harari, G. Müller, Ivo Nicolas Naranjo, Alina Mihaela Badescu, M. Prouza, Jeffrey Brack, M. Risse, Olaf Scholten, Jonathan Blazek, A. Schulz, Humberto Ibarguen Salazar, G. Parente, Fabrizia Canfora, Miguel Mostafa, R. Legumina, D. Garcia-Pinto, G. Marsella, A. López Casado, D. Rogozin, J. de Oliveira, Samo Stanič, Quentin Luce, Alex Kääpä, F. Suarez, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, Colin Baus, Martín Miguel Freire, M. Weber, Octavian Sima, V. Pirronello, H. Schieler, Antonella Castellina, G. P. Guedes, Jorn Schumacher, J. Debatin, A. Shadkam, A. F. Grillo, Juan Carlos D'Olivo, T. Pierog, P. L. Ghia, David Schmidt, Michael Urban, I. Al Samarai, Jeffrey A. Johnsen, S. Quinn, A. Segreto, Florian Gaté, V. de Souza, Eun-Joo Ahn, François Montanet, L. Caramete, Christian Sarmiento-Cano, L. Nellen, C. Morello, Peter L. Biermann, A. M. Kuotb Awad, J. A. J. Matthews, Paula Gina Isar, F. Salesa Greus, Nicolás González, Esteban Roulet, Corinne Berat, M. Giller, Q. Hasankiadeh, Z. Zong, B. Gookin, E. M. Santos, Bruce R. Dawson, P.O. Mazur, L. Niemietz, Tim Niggemann, J. Stasielak, S. Coutu, C. Porowski, Denise Boncioli, A. Aab, J. Biteau, Luis A. Nunez, Elton J. G. Santos, and K. Link

Subjects
Physics, Pierre Auger Observatory, High Energy Astrophysical Phenomena (astro-ph.HE), 010308 nuclear & particles physics, QC1-999, Astrophysics::High Energy Astrophysical Phenomena, Astrophysics::Instrumentation and Methods for Astrophysics, Spectral density, FOS: Physical sciences, Généralités, Astrophysics, 01 natural sciences, Auger, Interpretation (model theory), Acceleration, Physics and Astronomy (all), Observatory, 0103 physical sciences, Energy spectrum, Mass spectrum, Astrophysics - High Energy Astrophysical Phenomena, 010306 general physics
Abstract

We present a combined fit of a simple astrophysical model of UHECR sources to both the energy spectrum and mass composition data measured by the Pierre Auger Observatory. The fit has been performed for energies above 5 EeV, i.e. the region of the all-particle spectrum above the so-called "ankle"' feature. The astrophysical model we adopted consists of identical sources uniformly distributed in a comoving volume, where nuclei are accelerated with a rigidity-dependent mechanism. The fit results suggest sources characterized by relatively low maximum injection energies and hard spectral indices. The impact of various systematic uncertainties on the above result is discussed., 0, SCOPUS: cp.p, info:eu-repo/semantics/published

Published
2017
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50. Impact of atmospheric effects on the energy reconstruction of air showers observed by the surface detectors of the Pierre Auger Observatory

Author

Marco Torri, Denis Stanca, P. Abreu, D. Ravignani, M. Platino, M. Urban, A. C. Rovero, Alexandru Balaceanu, Vincenzo Rizi, D. Martello, M. Ziolkowski, Silvia Mollerach, O. Martínez Bravo, I. Jandt, Ralf Ulrich, R. Piegaia, G. Cataldi, V. Scherini, C. J. Todero Peixoto, N. Krohm, Alexandra Saftoiu, B. Sarkar, Christian Glaser, J. Espadanal, H. Wilczyński, B. García, Tobias Winchen, P. Lebrun, R. López, Karen S. Caballero-Mora, Alberto Daniel Supanitsky, Jose Chinellato, J. Kleinfeller, J. D. Swain, Martin Erdmann, E. Santos, Daniel Kuempel, Carlos Escobar, G. Torralba Elipe, Markus Roth, A. Letessier-Selvon, Gioacchino Alex Anastasi, Jesús Peña-Rodríguez, R. Krause, A. Śmiałkowski, Roger W Clay, D. Melo, P. Ruehl, A. Insolia, M. Kleifges, D. Zavrtanik, Stefano D'Amico, Lorenzo Cazon, A. Fuster, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, S. Sonntag, J. J. Beatty, J. Pȩkala, L. Valore, I.D. Vergara Quispe, Mariangela Settimo, L. Nellen, N. Fazzini, Jeffrey A. Johnsen, B. Vargas Cárdenas, T. Suomijärvi, J. Pallotta, E. J. Quel, A. van Vliet, Max Malacari, Lili Yang, Thomas Bretz, I. Valiño, C. Morello, J. Neuser, Corbin Covault, M. Zavrtanik, Piotr Homola, Julien Aublin, M. Josebachuili, David Walz, Ivone F. M. Albuquerque, M. Suarez Durán, Matías Rolf Hampel, Gaia Silli, A. Filipčič, R. M. Kieckhafer, David Wittkowski, Hernan Wahlberg, G. Salina, Igor Katkov, Eric Mayotte, M. Gómez Berisso, M. I. Micheletti, R. R. Prado, J. Rautenberg, Danielle LaHurd, Olivier Deligny, A. Parra, O. Wainberg, P. Ristori, Peter L. Biermann, M. Trini, S. Quinn, G. Kukec Mezek, Lino Miramonti, F. Sarazin, R. C. Shellard, A. Cancio, E. Varela, I. Allekotte, Dusan Mandat, Johannes Schulz, K.-H. Becker, M. Pimenta, J.D. Sanabria Gomez, Paolo Privitera, L. Villaseñor, S. Petrera, J. F. Valdés Galicia, Brian Fick, Marc Weber, Michael Unger, Francesco Strafella, I. De Mitri, Mario Buscemi, A. Segreto, Günter Sigl, Benedikt Zimmermann, Rúben Conceição, P. Heimann, Florian Lukas Briechle, J. Hulsman, A. Menshikov, Z. Zong, Petr Schovanek, A. Aab, Julian Kemp, G. Matthiae, M. A. Leigui de Oliveira, Roberto Mussa, D. Pakk Selmi-Dei, E. Kemp, R. Sato, Marco Giammarchi, L. Caramete, Serguei Vorobiov, J. R. Vázquez, D. Torres Machado, Alex Kääpä, Antonio Bueno, P. Sanchez-Lucas, D. Harari, D. Garcia-Pinto, Colin Baus, O. A. Taborda, Lourenco Lopes, Paul Sommers, A. Blanco, François Montanet, R. Squartini, G. S. Varner, T. Paul, Alfred Müller, L. Ochilo, P. Gouffon, H. Schieler, M. J. Cooper, H. Martinez, Carla Bleve, Karl-Heinz Kampert, F. Sánchez, Belén Andrada, Carlos Medina, Federico Suarez, Ricardo Vázquez, Ivo Nicolas Naranjo, Antonella Castellina, Paula Gina Isar, F. Salesa Greus, Gualberto Avila, M. Risse, Jonathan Blazek, G. C. Hill, Alina Mihaela Badescu, Radomir Smida, G. Medina-Tanco, G. van Aar, A. Di Matteo, Maria Rita Coluccia, Bruno Daniel, I. C. Mariç, Ralph Engel, M. Mallamaci, B. Wundheiler, Foteini Oikonomou, J. J. Masías Meza, G. De Mauro, C. Aramo, Gregory R Snow, P. H. Kasper, Jonathan Biteau, M. Prouza, Nicolás González, A.M. van den Berg, Darko Veberič, J. Ridky, Angela V. Olinto, Jörg R. Hörandel, B. Mitrica, S. Müller, Heino Falcke, E.M. Holt, Nicusor Arsene, A. Tapia, G. Parente, Fabrizia Canfora, R. Legumina, Esteban Roulet, H. Gemmeke, J. Vicha, I. Lhenry-Yvon, Corinne Berat, M. Giller, G. Marsella, A. Saleh, Maria-Teresa Dova, Q. Hasankiadeh, M. Perlin, D. Rogozin, J. de Oliveira, P. H. Nguyen, D. Nosek, C. Hojvat, Jan Ebr, R.J. Barreira Luz, E. M. Santos, Alejandro Almela, H.O. Klages, Bruce R. Dawson, P.O. Mazur, S. Messina, Johannes Schumacher, Andrej Dundovic, Lorenzo Caccianiga, V. M. Theodoro, Octavian Fratu, Valerio Verzi, B. Tome, G. Müller, Dariusz Glas, R.C. dos Anjos, V. de Souza, M. Palatka, A. Bridgeman, Luis A. Nunez, J. Stasielak, S. Coutu, S. J. Saffi, C. Porowski, Denise Boncioli, Marcus Niechciol, S. Querchfeld, M. J. Roncoroni, L. Niemietz, M. L. Díaz Castro, G. Farrar, Francesca Zuccarello, Tim Niggemann, I. Al Samarai, A. Criss, L. A. S. Pereira, Q. Luce, A. Taboada, G. P. Guedes, P.F. Gómez Vitale, Toshihiro Fujii, J. Debatin, A. Shadkam, Markus Lauscher, A. F. Grillo, Juan Carlos D'Olivo, T. Pierog, F. Pedreira, J. Phuntsok, Piera Luisa Ghia, Raul Sarmento, H. J. Mathes, A. Weindl, P. Stassi, David Schmidt, J. Rodriguez Rojo, A. G. Chavez, F.G. Schröder, Enrique Zas, Octavian Sima, C. Di Giulio, Fernando Contreras, M. Schauer, B. Revenu, D. Heck, Peter Gorham, Charles Timmermans, L. Collica, T. Huege, Jeffrey Brack, Olaf Scholten, Humberto Ibarguen Salazar, C. A. Sarmiento, F. Gate, Peter Hansen, Miguel Mostafa, L. Perrone, Jiri Chudoba, L. Tomankova, Alessio Gorgi, F. Guarino, John Matthews, A. López Casado, Samo Stanič, Peter Buchholz, R. Gaior, I.M. Brancus, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, Thomas Harrison, H. Glass, Martín Miguel Freire, Carola Dobrigkeit, M. Plum, V. Pirronello, Marco Aglietta, P. Pieroni, M. E. Bertaina, F. Arqueros, Alan Watson, Kai Daumiller, Martina Bohacova, Mihai Niculescu-Oglinzanu, J. Alvarez Castillo, K. Link, J. Sorokin, A. Lucero, Miroslav Hrabovský, O. Kambeitz, M. Schimp, A. Haungs, A. Kuotb Awad, J. L. Harton, S. G. Blaess, P. Mantsch, Z. Szadkowski, Ana Martina Botti, F. Diogo, V. Novotny, Rossella Caruso, S. Mathys, M. Erfani, R. M. de Almeida, Lukas Middendorf, Christine Peters, Miroslav Pech, A. Yushkov, Rodrigo Pelayo, Stijn Buitink, Pavel Horvath, D. Yelos, G. Rodriguez Fernandez, Hernán Asorey, R. Ramos-Pollan, Sofia Andringa, Marcio Aparecido Muller, H. Nožka, Daniela Mockler, W. Rodrigues de Carvalho, J. W. Cronin, P. van Bodegom, G. Golup, Nataliia Borodai, N. Kunka, S. J. De Jong, Pierre Billoir, Ugo Giaccari, J. R. T. de Mello Neto, J. A.J. Matthews, Xavier Bertou, A. Zepeda, Pedro Assis, A. Etchegoyen, Luis A. Anchordoqui, Jaime Alvarez-Muñiz, Philipp Papenbreer, Alexandru Gherghel-Lascu, Petr Travnicek, Alan Coleman, Trent D. Grubb, Juan Manuel Figueira, Roberta Colalillo, A. G. Mariazzi, I. A. Minaya, B. Keilhauer, André Schulz, S. J. Sciutto, D. Nitz, A. E. Herve, L. R. Wiencke, S. Jansen, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire SUBATECH Nantes (SUBATECH), Mines Nantes (Mines Nantes)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Pierre AUGER, Aab, A., Abreu, P., Aglietta, M., Samarai, I. Al, Albuquerque, I. F. M., Allekotte, I., Almela, A., Castillo, J. Alvarez, Alvarez Muñiz, J., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Arqueros, F., Arsene, N., Asorey, H., Assis, P., Aublin, J., Avila, G., Badescu, A. M., Balaceanu, A., Luz, R. J. Barreira, Baus, C., Beatty, J. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Billoir, P., Biteau, J., Blaess, S. G., Blanco, A., Blazek, J., Bleve, C., Boháčová, M., Boncioli, D., Bonifazi, C., Borodai, N., Botti, A. M., Brack, J., Brancus, I., Bretz, T., Bridgeman, A., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero Mora, K. S., Caccianiga, L., Cancio, A., Canfora, F., Caramete, L., Caruso, R., Castellina, A., Cataldi, G., Cazon, L., Chavez, A. G., Chinellato, J. A., Chudoba, J., Clay, R. W., Colalillo, Roberta, Coleman, A., Collica, L., Coluccia, M. R., Conceição, R., Contreras, F., Cooper, M. J., Coutu, S., Covault, C. E., Criss, A., Cronin, J., D'Amico, S., Daniel, B., Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Jong, S. J., Mauro, G. De, Neto, J. R. T. de Mello, Mitri, I. De, de Oliveira, J., de Souza, V., Debatin, J., Deligny, O., Giulio, C. Di, Matteo, A. Di, Castro, M. L. Díaz, Diogo, F., Dobrigkeit, C., D'Olivo, J. C., Anjos, R. C. do, Dova, M. T., Dundovic, A., Ebr, J., Engel, R., Erdmann, M., Erfani, M., Escobar, C. O., Espadanal, J., Etchegoyen, A., Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Fick, B., Figueira, J. M., Filipčič, A., Fratu, O., Freire, M. M., Fujii, T., Fuster, A., Gaior, R., García, B., Garcia Pinto, D., Gaté, F., Gemmeke, H., Gherghel Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Głas, D., Glaser, C., Glass, H., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, González, N., Gorgi, A., Gorham, P., Gouffon, P., Grillo, A. F., Grubb, T. D., Guarino, Fausto, Guedes, G. P., Hampel, M. R., Hansen, P., Harari, D., Harrison, T. A., Harton, J. L., Hasankiadeh, Q., Haungs, A., Hebbeker, T., Heck, D., Heimann, P., Herve, A. E., Hill, G. C., Hojvat, C., Holt, E., Homola, P., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Jandt, I., Jansen, S., Johnsen, J. A., Josebachuili, M., Kääpä, A., Kambeitz, O., Kampert, K. H., Kasper, P., Katkov, I., Keilhauer, B., Kemp, E., Kemp, J., Kieckhafer, R. M., Klages, H. O., Kleifges, M., Kleinfeller, J., Krause, R., Krohm, N., Kuempel, D., Mezek, G. Kukec, Kunka, N., Awad, A. Kuotb, Lahurd, D., Lauscher, M., Lebrun, P., Legumina, R., de Oliveira, M. A. Leigui, Letessier Selvon, A., Lhenry Yvon, I., Link, K., Lopes, L., López, R., Casado, A. López, Luce, Q., Lucero, A., Malacari, M., Mallamaci, M., Mandat, D., Mantsch, P., Mariazzi, A. G., Mariç, I. C., Marsella, G., Martello, D., Martinez, H., Bravo, O. Martínez, Meza, J. J. Masía, Mathes, H. J., Mathys, S., Matthews, J., Matthews, J. A. J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina, C., Medina Tanco, G., Melo, D., Menshikov, A., Messina, S., Micheletti, M. I., Middendorf, L., Minaya, I. A., Miramonti, L., Mitrica, B., Mockler, D., Mollerach, S., Montanet, F., Morello, C., Mostafá, M., Müller, A. L., Müller, G., Muller, M. A., Müller, S., Mussa, R., Naranjo, I., Nellen, L., Neuser, J., Nguyen, P. H., Niculescu Oglinzanu, M., Niechciol, M., Niemietz, L., Niggemann, T., Nitz, D., Nosek, D., Novotny, V., Nožka, H., Núñez, L. A., Ochilo, L., Oikonomou, F., Olinto, A., Selmi Dei, D. Pakk, Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Paul, T., Pech, M., Pedreira, F., Pȩkala, J., Pelayo, R., Peña Rodriguez, J., Pereira, L. A. S., Perlín, M., Perrone, L., Peters, C., Petrera, S., Phuntsok, J., Piegaia, R., Pierog, T., Pieroni, P., Pimenta, M., Pirronello, V., Platino, M., Plum, M., Porowski, C., Prado, R. R., Privitera, P., Prouza, M., Quel, E. J., Querchfeld, S., Quinn, S., Ramos Pollan, R., Rautenberg, J., Ravignani, D., Revenu, B., Ridky, J., Risse, M., Ristori, P., Rizi, V., de Carvalho, W. Rodrigue, Fernandez, G. Rodriguez, Rojo, J. Rodriguez, Rogozin, D., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salazar, H., Saleh, A., Greus, F. Salesa, Salina, G., Gomez, J. D. Sanabria, Sánchez, F., Sanchez Lucas, P., Santos, E. M., Santos, E., Sarazin, F., Sarkar, B., Sarmento, R., Sarmiento, C. A., Sato, R., Schauer, M., Scherini, V., Schieler, H., Schimp, M., Schmidt, D., Scholten, O., Schovánek, P., Schröder, F. G., Schulz, A., Schulz, J., Schumacher, J., Sciutto, S. J., Segreto, A., Settimo, M., Shadkam, A., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Śmiałkowski, A., Šmída, R., Snow, G. R., Sommers, P., Sonntag, S., Sorokin, J., Squartini, R., Stanca, D., Stanič, S., Stasielak, J., Stassi, P., Strafella, F., Suarez, F., Durán, M. Suarez, Sudholz, T., Suomijärvi, T., Supanitsky, A. D., Swain, J., Szadkowski, Z., Taboada, A., Taborda, O. A., Tapia, A., Theodoro, V. M., Timmermans, C., Peixoto, C. J. Todero, Tomankova, L., Tomé, B., Elipe, G. Torralba, Machado, D. Torre, Torri, M., Travnicek, P., Trini, M., Ulrich, R., Unger, M., Urban, M., Galicia, J. F. Valdé, Valiño, I., Valore, Laura, Aar, G. van, Bodegom, P. van, Berg, A. M. van den, Vliet, A. van, Varela, E., Cárdenas, B. Varga, Varner, G., Vázquez, J. R., Vázquez, R. A., Veberič, D., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Villaseñor, L., Vorobiov, S., Wahlberg, H., Wainberg, O., Walz, D., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczyński, H., Winchen, T., Wittkowski, D., Wundheiler, B., Yang, L., Yelos, D., Yushkov, A., Zas, E., Zavrtanik, D., Zavrtanik, M., Zepeda, A., Zimmermann, B., Ziolkowski, M., Zong, Z., Zuccarello, F., Bleve, Carla, Colalillo, R., Coluccia, MARIA RITA, D'Amico, Stefano, DE MITRI, Ivan, Guarino, F., Marsella, Giovanni, Martello, Daniele, Perrone, Lorenzo, Strafella, Francesco, Valore, L., Physics, Elementary Particle Physics, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), and Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Nantes (UN)-Mines Nantes (Mines Nantes)

Subjects
[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Astronomy, Astrophysics::High Energy Astrophysical Phenomena, Cherenkov detectors, Data analysis, Large detector systems for particle and astroparticle physics, Systematic effects, FOS: Physical sciences, Cosmic ray, Cherenkov detectors Data analysis, Instrumentation, Mathematical Physics, 01 natural sciences, Auger, Nuclear physics, Observatory, 0103 physical sciences, Density of air, High Energy Physics, 010303 astronomy & astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Physics::Atmospheric and Oceanic Physics, Pierre Auger Observatory, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), 010308 nuclear & particles physics, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Física, 13. Climate action, Experimental High Energy Physics, RECONHECIMENTO DE PADRÕES, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Física nuclear, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Event (particle physics), ultra-high energy cosmic rays, extensive air showers, atmospheric effects, Energy (signal processing)
Abstract

Atmospheric conditions, such as the pressure (P), temperature (T) or air density ( / P=T), affect the development of extended air showers initiated by energetic cosmic rays. We study the impact of the atmospheric variations on the reconstruction of air showers with data from the arrays of surface detectors of the Pierre Auger Observatory, considering separately the one with detector spacings of 1500m and the one with 750m spacing. We observe modulations in the event rates that are due to the influence of the air density and pressure variations on the measured signals, from which the energy estimators are obtained. We show how the energy assignment can be corrected to account for such atmospheric effects., La lista completa de autores puede verse al final del archivo asociado a este registro., Instituto de Física La Plata

Published
2017

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