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2. ARDS

Author

Rosseau, S., Suttorp, N., Zerkowski, H. -R., editor, and Baumann, G., editor

Published
2006
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13. Epidemiology, Diagnosis and Treatment of Adult Patients with Nosocomial Pneumonia - Update 2017

Author

Dalhoff, K., Abele-Horn, M., Andreas, S., Deja, M., Ewig, S., Gastmeier, P., Gatermann, S., Gerlach, H., Grabein, B., Heussel, C. P., Hoeffken, G., Kolditz, M., Kramme, E., Kuehl, H., Lange, C., Mayer, K., Nachtigall, I., Panning, M., Pletz, M., Rath, P-M., Rohde, G., Rosseau, S., Schaaf, B., Schreiter, D., Schuette, H., Seifert, H., Spies, C., Welte, T., Dalhoff, K., Abele-Horn, M., Andreas, S., Deja, M., Ewig, S., Gastmeier, P., Gatermann, S., Gerlach, H., Grabein, B., Heussel, C. P., Hoeffken, G., Kolditz, M., Kramme, E., Kuehl, H., Lange, C., Mayer, K., Nachtigall, I., Panning, M., Pletz, M., Rath, P-M., Rohde, G., Rosseau, S., Schaaf, B., Schreiter, D., Schuette, H., Seifert, H., Spies, C., and Welte, T.

Abstract

Nosocomial pneumonia (HAP) is a frequent complication of hospital care. Most data are available on ventilator-associated pneumonia. However, infections on general wards are increasing. A central issue are infections with multidrug resistant (MDR) pathogens which are difficult to treat in the empirical setting potentially leading to inappropriate use of antimicrobial therapy. This guideline update was compiled by an interdisciplinary group on the basis of a systematic literature review. Recommendations are made according to GRADE giving guidance for the diagnosis and treatment of HAP on the basis of quality of evidence and benefit/risk ratio. This guideline has two parts. First an update on epidemiology, spectrum of pathogens and antimicrobials is provided. In the second part recommendations for the management of diagnosis and treatment are given. New recommendations with respect to imaging, diagnosis of nosocomial viral pneumonia and prolonged infusion of antibacterial drugs have been added. The statements to risk factors for infections with MDR pathogens and recommendations for monotherapy vs combination therapy have been actualised. The importance of structured deescalation concepts and limitation of treatment duration is emphasized.

Published
2018

15. Bone marrow and chelatable iron in patients with protein energy malnutrition

Author

Sive, AA, Dempster, WS, Rosseau, S, Kelly, M, Malan, H, and de V. Heese, H

Abstract

Objectives: To examine the iron status of malnourished children by comparing bone marrow iron deposits in children with protein energy malnutrition with those in well-nourished controls, and measuring chelatable urinary iron excretion in children with kwashiorkor. Design: Bone marrow iron was assessed histologicaHy in postmortem specimens from children with kwashiorkor or marasmus, and from controls. Twenty-four-hour urinary iron was measured in children with severe kwashiorkor, half of whom received 10 mg/kg of intramuscular desferrioxamine (DFO) on admission. Setting: Red Cross War Memorial Children's Hospital, Cape Town. Subjects: Thirteen children with kwashiorkor, 6 with marasmus and 16 well-nourished children underwent bone marrow examination. Urinary iron excretion was assayed in 17 children with kwashiorkor. Results: Stainable iron was present in the bone marrow of half the children with kwashiorkor but in only 1 child in each of the other groups. The median iron excretion was 945.5 µg/24 hours in the DFO group compared with 28.5 µg/24 hours in the non-DFO group. Conclusions: There is an apparent excess of iron which may predispose to bacterial infections and free radicalmediated injury in children with kwashiorkor. S AFr Med J 1996; 86: 1410-1413

Published
2017

19. Misplaced iron in kwashiorkor

Author

Dempster, W.S., Sive, A.A., Rosseau, S., Malan, H., and Heese, Hde V.

Subjects
Kwashiorkor -- Prevention, Iron in the body -- Analysis, Free radicals (Chemistry) -- Physiological aspects, South Africa -- Health aspects
Abstract

A comparative study of 50 children with kwashiorkor, six children with marasmus and 12 well-nourished children at the Red Cross War Memorial Children's Hospital, Cape Town, South Africa, reveals the harmful impact of free radical injuries in the growth and progression of kwashiorkor in children. While marasmic and healthy subjects were free from any radical promoting iron, almost 60% of the children with kwashiorkor had non-protein-bound iron in their plasmas, revealing the need for the removal of this free iron occurrence to decrease mortality rates among children.

Published
1995

20. Transition from in-hospital ventilation to home ventilation: process description and quality indicators

Author

Kastrup, M, Tittmann, B, Sawatzki, T, Gersch, M, Vogt, C, Rosenthal, M, Rosseau, S, Spies, C, Kastrup, M, Tittmann, B, Sawatzki, T, Gersch, M, Vogt, C, Rosenthal, M, Rosseau, S, and Spies, C

Abstract

The current demographic development of our society results in an increasing number of elderly patients with chronic diseases being treated in the intensive care unit. A possible long-term consequence of such a treatment is that patients remain dependent on certain invasive organ support systems, such as long-term ventilator dependency. The main goal of this project is to define the transition process between in-hospital and out of hospital (ambulatory) ventilator support. A further goal is to identify evidence-based quality indicators to help define and describe this process.This project describes an ideal sequence of processes (process chain), based on the current evidence from the literature. Besides the process chain, key data and quality indicators were described in detail. Due to the limited project timeline, these indicators were not extensively tested in the clinical environment.The results of this project may serve as a solid basis for proof of feasibility and proof of concept investigations, optimize the transition process of ventilator-dependent patients from a clinical to an ambulatory setting, as well as reduce the rate of emergency re-admissions., Durch die demographische Entwicklung bedingt werden zunehmend ältere Patienten mit chronischen Begleiterkrankungen intensivmedizinisch versorgt. Als eine mögliche Folge einer solchen Intensivbehandlung kann bei diesen Patienten eine chronische Abhängigkeit von apparativen Organersatzverfahren resultieren, welche im Bereich der Beatmung in einer Langzeitbeatmung resultiert. Ziel dieses durch das BMBF geförderte Projekt "Beatmungspflege@home" ist die Definition des Überleitprozesses von der klinischen Beatmung in die außerklinische Beatmung und die Entwicklung von evidenzbasierten Qualitätsindikatoren um diesen Prozess der Überleitung transparent darzustellen. Im Projektverlauf wurde eine Soll-Prozesskette, unter Berücksichtigung der aktuellen Literatur in Bezug auf die Evidenzlage, erstellt. Anhand dieser Soll-Prozesskette wurden parallel die Kennzahlen und Qualitätsindikatoren detailliert definiert und konsentiert. Aus Gründen der begrenzten Projektlaufzeit konnte kein ausführlicher Feldtest zur Evaluation der Praxistauglichkeit durchgeführt werden. Die Projektbeteiligten hoffen, dass die Ergebnisse des Projektes eine solide Grundlage darstellen, um im Anschlussprojekt einen "proof of concept" untersuchen zu können, um damit den Überleitprozess in die außerklinische Beatmung qualitativ zu verbessern und somit unnötige Klinikeinweisungen zu verhindern.

Published
2017

23. Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection

Author

Martin Loeches, I, Lisboa, T, Rhodes, A, Moreno, Rp, Silva, E, Sprung, C, Chiche, Jd, Barahona, D, Villabon, M, Balasini, C, Pearse, Rm, Matos, R, Rello, J, Rodriguez, A, Capuzzo, M, Reina, R, Marsh, B, Flaaten, H, Sigurdsson, G, Ivana, Z, Cerny, V, Quintel, M, Welte, T, Mayorga, M, Offenstadt, G, Guidet, B, Levin, P, Rothen, Hu, Gomersall, C, Hashemian, Sm, Katsanoulas, C, Mouloudi, H, Kapadia, F, Valentin, A, Hedenstierna, G, Perner, A, Bugedo, G, Ruokonen, E, Soriano Arandes, A, Montejo, Jc, Peñíscola, R, Hermosa, C, Gordo, F, Latour, J, Vidaur, L, Alvarez Gonzalez, M, Alvarez Rocha, L, De Pablo, A, Ferri, C, Lopez De Arbina Martinez, Cânones, C, Insausti, J, Cambronero, J, Galvan, B, Luna, J, Blancas, R, Garcia, C, Sierra, R, Fernández Dorado, F, Monedero, P, Llagunes, J, Cobo, P, Socias, A, Leon Lopez, R, Esteban, E, Lacueva, M, Magret, M, Del Nogal, F, Dinis, A, Bártolo, A, Ramos, A, Franca, C, Estevens, C, Granja, C, Fidalgo, C, Almeida, E, Lafuente, E, Rua, F, Esteves, F, Clemente, J, Nóbrega, Jj, Pereira, Jm, Moura, Jp, Silva LP, Trindade E., Telo, L, Santos, L, Pedrosa, Mj, Oliveira, M, Resende, M, Catorze, N, Coutinho, P, Ribeiro, R, Miranda, I, Cardoso, T, Branco, V, Bellani, G, Urbino, R, Peris, A, Amatu, A, Berlot, G, Marzani, Fc, Corbanese, U, David, Antonio, Chiarandini, P, Della Corte, F, Caspani, Ml, Conio, A, Mangani, V, Tetamo, R, Wolfler, A, Tappatà, G, Vivaldi, N, Bertolini, G, Pelagalli, L, Molin, A, Girardis, M, Gristin, G, Lam, A, Crabb, I, Cusack, R, Jackson, R, Veerappan, C, Whiteley, C, Ware, T, Krueper, S, Mckinstry, C, Ferguson, A, Rubulotta, F, Valencia, E, Gonzalez, S, Cevallos, V, Zazu, A, Chaparro Fresco JN, Galindez, G, Barrios, C, Lovesio, C, Villamagua, B, Cadena, M, Salgado, E, García, Mf, Paredes, G, Donnelly, M, O'Croinin, D, Bates, J, Kavanagh, N, O'Brien, B, Plant, R, Scully, M, Farragher, R, Oliveira, L, Mataloun, S, Dantas, Vs, Simvoulidis, L, Duarte, P, Grion, C, Germano, A, Laake, Jh, Helset, E, Klausen, D, Flaatten, H, Bruheim, K, Kristinsson, B, Sigurdsson, Se, Hrubý, J, Valkova, R, Janda, R, Zykova, I, Kernchen, A, Bloos, F, Rosseau, S, Krassler, J, Fischer, F, Arroyo Sanchez, A, Barrionuevo Poquet, A, Ramos Palomino, I, Rafael, F, Salasfoch, J, Dubar, G, Tonnelier, Jm, Barbar, S, Dobrzynski, M, Mignon, A, Jakobson, D, Klein, M, Segal, E, Barlavie, Y, Hersch, M, Salomón, Zs, Zender, H, Chan, K, Buckley, T, Batranovic, U, Schaffer, I, Sretkovic, J, Koulenti, D, Mouloudi, E, Clouva Molyvdas PM, Gurjar, M, Vijayan, D, Hinterholzer, G, Kulier, A, Verlaat, C, Ebel, D, Persson, J, Walther, S, Petersen, P, Swinnen, W, Collin, V, Olsen, H, Gutierrez, P, Thiery, G, Laine, H, Rumba, A, Maiyalagan, S, Bui, T., Martin-Loeches, I., Lisboa, T., Rhodes, A., Moreno, R. P., Silva, E., Sprung, C., Chiche, J. -D., Barahona, D., Villabon, M., Balasini, C., Pearse, R., Matos, R., Rello, J., Rodriguez, A., Capuzzo, M., Reina, R., Marsh, B., Flaaten, H., Sigurdsson, G., Ivana, Z., Cerny, V., Quintel, M., Welte, T., Mayorga, M., Offenstadt, G., Guidet, B., Levin, P., Rothen, H. -U., Gomersall, C., Hashemian, S. M., Katsanoulas, C., Mouloudi, H., Kapadia, F., Valentin, A., Hedenstierna, G., Perner, A., Bugedo, G., Ruokonen, E., Arandes, A. S., Montejo, J. C., Peniscola, R., Hermosa, C., Gordo, F., Latour, J., Vidaur, L., Alvarez-Gonzalez, M., Alvarez-Rocha, L., De Pablo, A., Ferri, C., De Arbina Martinez, L., Canones, C., Insausti, J., Cambronero, J., Galvan, B., Luna, J., Blancas, R., Garcia, C., Sierra, R., Dorado, F. F., Monedero, P., Llagunes, J., Cobo, P., Socias, A., Leon-Lopez, R., Esteban, E., Lacueva, M., Magret, M., Del Nogal, F., Dinis, A., Bartolo, A., Ramos, A., Franca, C., Estevens, C., Granja, C., Fidalgo, C., Almeida, E., Lafuente, E., Rua, F., Esteves, F., Clemente, J., Nobrega, J. J., Pereira, J. M., Moura, J. P., Trindade E Silva, L. P., Telo, L., Santos, L., Pedrosa, M. J., Oliveira, M., Resende, M., Catorze, N., Coutinho, P., Ribeiro, R., Moreno, R., Miranda, I., Cardoso, T., Branco, V., Bellani, G., Urbino, R., Peris, A., Amatu, A., Berlot, G., Marzani, F. C., Corbanese, U., David, A., Chiarandini, P., Corte, F. D., Caspani, M. L., Alessandra, C., Mangani, V., Tetamo, R., Wolfler, A., Tappata, G., Nicoletta, V., Bertolini, G., Pelagalli, L., Molin, A., Girardis, M., Gristin, G., Lam, A., Crabb, I., Cusack, R., Jackson, R., Veerappan, C., Whiteley, C., Ware, T., Krueper, S., Mckinstry, C., Ferguson, A., Rubulotta, F., Valencia, E., Gonzalez, S., Cevallos, V., Zazu, A., Fresco, J. N. C., Galindez, G., Barrios, C., Lovesio, C., Villamagua, B., Cadena, M., Salgado, E., Garcia, M. F., Paredes, G., Donnelly, M., O'Croinin, D., Bates, J., Kavanagh, N., O'Brien, B., Plant, R., Scully, M., Farragher, R., Oliveira, L., Mataloun, S., Dantas, V. S., Simvoulidis, L., Duarte, P., Grion, C., Germano, A., Laake, J. H., Helset, E., Klausen, D., Flaatten, H., Bruheim, K., Kristinsson, B., Sigurdsson, S. E., Hruby, J., Valkova, R., Janda, R., Zykova, I., Kernchen, A., Bloos, F., Rosseau, S., Krassler, J., Fischer, F., Arroyo-Sanchez, A., Poquet, A. B., Palomino, I. R., Rafael, F., Salasfoch, J., Dubar, G., Tonnelier, J. -M., Barbar, S., Dobrzynski, M., Mignon, A., Jakobson, D., Klein, M., Segal, E., Barlavie, Y., Hersch, M., Salomon, Z. S., Zender, H., Rothen, H. U., Chan, K., Buckley, T., Batranovic, U., Schaffer, I., Sretkovic, J., Koulenti, D., Mouloudi, E., Clouva-Molyvdas, P. -M., Gurjar, M., Vijayan, D., Hinterholzer, G., Kulier, A., Verlaat, C., Ebel, D., Persson, J., Walther, S., Petersen, P., Swinnen, W., Collin, V., Olsen, H., Gutierrez, P., Thiery, G., Laine, H., Rumba, A., Maiyalagan, S., Bui, T., Martin Loeches, I, Lisboa, T, Rhodes, A, Moreno, R, Silva, E, Sprung, C, Chiche, J, Barahona, D, Villabon, M, Balasini, C, Pearse, R, Matos, R, Rello, J, and Pesenti, A

Subjects
Registrie, Male, Original, H1N1 Influenza, Adrenal Cortex Hormone, Critical Care and Intensive Care Medicine, Severity of Illness Index, law.invention, Influenza A Virus, H1N1 Subtype, Community-acquired pneumonia, Adrenal Cortex Hormones, law, Prospective Studies, Registries, 610 Medicine & health, Prospective cohort study, H1N1 Subtype, Influenza, Acute Respiratory Distress Syndrome, Cross Infection, Likelihood Functions, COPD, Acinetobacter, Hazard ratio, Middle Aged, Likelihood Function, Intensive care unit, Europe, Intensive Care Units, Community acquired pneumonia, Corticosteroid therapy, Pandemic (H1N1)v influenza A infection, Female, Survival Analysi, Human, Adult, medicine.medical_specialty, Chronic Obstructive Pulmonary Disease, ARDS, Community acquired pneumonia, Corticosteroid therapy, Pandemic (H1N1)v influenza A infection, Intensive Care Unit, Internal medicine, Correspondence, Influenza, Human, Severity of illness, medicine, Humans, H1N1 Subtype, Intensive care medicine, Pandemics, Pandemic, business.industry, Pneumonia, Odds ratio, medicine.disease, Survival Analysis, Influenza, Asthma, Prospective Studie, business
Abstract

Introduction: Early use of corticosteroids in patients affected by pandemic (H1N1)v influenza A infection, although relatively common, remains controversial. Methods: Prospective, observational, multicenter study from 23 June 2009 through 11 February 2010, reported in the European Society of Intensive Care Medicine (ESICM) H1N1 registry. Results: Two hundred twenty patients admitted to an intensive care unit (ICU) with completed outcome data were analyzed. Invasive mechanical ventilation was used in 155 (70.5%). Sixty-seven (30.5%) of the patients died in ICU and 75 (34.1%) whilst in hospital. One hundred twenty-six (57.3%) patients received corticosteroid therapy on admission to ICU. Patients who received corticosteroids were significantly older and were more likely to have coexisting asthma, chronic obstructive pulmonary disease (COPD), and chronic steroid use. These patients receiving corticosteroids had increased likelihood of developing hospital-acquired pneumonia (HAP) [26.2% versus 13.8%, p < 0.05; odds ratio (OR) 2.2, confidence interval (CI) 1.1-4.5]. Patients who received corticosteroids had significantly higher ICU mortality than patients who did not (46.0% versus 18.1%, p < 0.01; OR 3.8, CI 2.1-7.2). Cox regression analysis adjusted for severity and potential confounding factors identified that early use of corticosteroids was not significantly associated with mortality [hazard ratio (HR) 1.3, 95% CI 0.7-2.4, p = 0.4] but was still associated with an increased rate of HAP (OR 2.2, 95% CI 1.0-4.8, p < 0.05). When only patients developing acute respiratory distress syndrome (ARDS) were analyzed, similar results were observed. Conclusions: Early use of corticosteroids in patients affected by pandemic (H1N1)v influenza A infection did not result in better outcomes and was associated with increased risk of superinfections. associated with mortality [hazard ratio (HR) 1.3, 95% CI 0.7-2.4, p = 0.4] but was still associated with an increased rate of HAP (OR 2.2, 95% CI 1.0-4.8, p < 0.05). When only patients developing acute respiratory distress syndrome (ARDS) were analyzed, similar results were observed. Conclusions: Early use of corticosteroids in patients affected by pandemic (H1N1)v influenza A infection did not result in better outcomes and was associated with increased risk of superinfections. © Copyright jointly held by Springer and ESICM 2010.

Published
2011

25. [Epidemiology, diagnosis and treatment of adult patients with nosocomial pneumonia. S-3 Guideline of the German Society for Anaesthesiology and Intensive Care Medicine, the German Society for Infectious Diseases, the German Society for Hygiene and Microbiology, the German Respiratory Society and the Paul-Ehrlich-Society for Chemotherapy]

Author

Dalhoff, K., Abele-Horn, M., Andreas, S., Bauer, T., Baum, H., Deja, M., Ewig, S., Gastmeier, P., Gatermann, S., Gerlach, H., Grabein, B., Hoffken, G., Kern, W.V., Kramme, E., Lange, C., Lorenz, J., Mayer, K., Nachtigall, I., Pletz, M., Rohde, G., Rosseau, S., Schaaf, B., Schaumann, R., Schreiter, D., Schutte, H., Seifert, H., Sitter, H., Spies, C., Welte, T., Pulmonologie, and RS: NUTRIM - R3 - Chronic inflammatory disease and wasting

Subjects
Adult, Male, Microbiological Techniques, Cross Infection, Germany, Pneumonia, Bacterial, Pulmonary Medicine, Humans, Female, Anti-Bacterial Agents
Abstract

Nosocomial pneumonia (HAP) is a frequent complication of hospital care. Most data are available on ventilator-associated pneumonia. However infections on general wards are also increasing. A central issue are infections with multi drug resistant (MDR) pathogens which are difficult to treat particularly in the empirical setting potentially leading to inappropriate use of antimicrobial therapy. This guideline was compiled by an interdisciplinary group on the basis of a systematic literature review. Recommendations are made according to GRADE giving guidance for the diagnosis and therapy of HAP on the basis of quality of evidence and benefit/risk ratio. The guideline has two parts. First an update on epidemiology, spectrum of pathogens and antiinfectives is provided. In the second part recommendations for the management of diagnosis and treatment are given. Proper microbiologic work up is emphasized for knowledge of the local patterns of microbiology and drug susceptibility. Moreover this is the optimal basis for deescalation in the individual patient. The intensity of antimicrobial therapy is guided by the risk of infections with MDR. Structured deescalation concepts and strict limitation of treatment duration should lead to reduced selection pressure.

Published
2012

26. S2k-Guideline “Prolonged Weaning”

Author

Schönhofer, B., additional, Geiseler, J., additional, Dellweg, D., additional, Moerer, O., additional, Barchfeld, T., additional, Fuchs, H., additional, Karg, O., additional, Rosseau, S., additional, Sitter, H., additional, Weber-Carstens, S., additional, Westhoff, M., additional, and Windisch, W., additional

Published
2015
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27. Management der Influenza A/H1N1 - Pandemie im Krankenhaus: Update Januar 2010. Eine Stellungnahme der Deutschen Gesellschaft fur Pneumologie und Beatmungsmedizin

Author

Schaberg, T., Bauer, T., Dalhoff, K., Ewig, S., Kohler, D., Lorenz, J., Rohde, G., Pletz, M.W., Rosseau, S., Schaaf, B., Suttorp, N., Welte, T., Haas, W., Reuss, A., Pulmonologie, and RS: NUTRIM - R3 - Chronic inflammatory disease and wasting

Subjects
virus diseases
Abstract

This update summarized the hospital experience from the first wave of the new influenza A/H1/N1 pandemic.

Published
2010

28. Plasma free iron: a possible cause of oedema in kwashiorkor

Author

H Malan, H D Heese, Rosseau S, A. A. Sive, and W S Dempster

Subjects
medicine.medical_specialty, Iron, Serum albumin, Gastroenterology, Teaching hospital, Edema, Internal medicine, Blood plasma, medicine, Humans, Child, Serum Albumin, chemistry.chemical_classification, biology, business.industry, Transferrin, Kwashiorkor, Infant, Original Articles, medicine.disease, Malnutrition, Endocrinology, chemistry, Child, Preschool, Pediatrics, Perinatology and Child Health, biology.protein, Etiology, medicine.symptom, business
Abstract

Accepted 22 October 1996 BACKGROUND—Oedema is a sine qua non for the diagnosis of kwashiorkor yet the mechanisms leading to oedema remain ill defined. AIMS—To relate the plasma concentration of radical promoting `free' iron to the degree of oedema in patients with kwashiorkor. SETTING—University teaching hospital. PATIENTS—Fifteen children with kwashiorkor, nine of whom had severe and six of whom had a moderate degree of oedema. METHODS—Plasma `free' iron was measured as bleomycin detectable iron (BDI) and related to severity of oedema and plasma albumin concentration. RESULTS—BDI was significantly higher in the patients with severe oedema (20.5 v 6.75 µmol/l) whereas the albumin concentrations were similar (16 v 17 g/l). BDI was no longer present in any patients 30 days after admission. CONCLUSIONS—`Free' circulating iron may contribute to the oedema of kwashiorkor, and its sequestration could hasten recovery and decrease morbidity and mortality.

Published
1997

30. Prolongiertes Weaning

Author

Schönhofer, B., additional, Geiseler, J., additional, Dellweg, D., additional, Moerer, O., additional, Barchfeld, T., additional, Fuchs, H., additional, Karg, O., additional, Rosseau, S., additional, Sitter, H., additional, Weber-Carstens, S., additional, Westhoff, M., additional, and Windisch, W., additional

Published
2014
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32. Epidemiologie, Diagnostik und Therapie erwachsener Patienten mit nosokomialer Pneumonie

Author

Dalhoff, K., additional, Abele-Horn, M., additional, Andreas, S., additional, Bauer, T., additional, von Baum, H., additional, Deja, M., additional, Ewig, S., additional, Gastmeier, P., additional, Gatermann, S., additional, Gerlach, H., additional, Grabein, B., additional, Höffken, G., additional, Kern, W., additional, Kramme, E., additional, Lange, C., additional, Lorenz, J., additional, Mayer, K., additional, Nachtigall, I., additional, Pletz, M., additional, Rohde, G., additional, Rosseau, S., additional, Schaaf, B., additional, Schaumann, R., additional, Schreiter, D., additional, Schütte, H., additional, Seifert, H., additional, Sitter, H., additional, Spies, C., additional, and Welte, T., additional

Published
2012
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38. Management der Influenza-A/H1N1-Pandemie im Krankenhaus: Update Januar 2010

Author

Schaberg, T., primary, Bauer, T., additional, Dalhoff, K., additional, Ewig, S., additional, Köhler, D., additional, Lorenz, J., additional, Rohde, G., additional, Pletz, M.W., additional, Rosseau, S., additional, Schaaf, B., additional, Suttorp, N., additional, Welte, T., additional, Haas, W., additional, and Reuß, A., additional

Published
2010
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41. Simvastatin attenuates ventilator-induced lung injury in mice

Author

Müller, HC, primary, Witzenrath, M, additional, Hellwig, K, additional, Tschernig, T, additional, Schmiedel, A, additional, Gutbier, B, additional, Schmeck, B, additional, Hippenstiel, S, additional, Peters, H, additional, Suttorp, N, additional, and Rosseau, S, additional

Published
2010
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42. Palliativmedizin in der Pneumologie

Author

Magnussen, H., primary, Heigener, D., additional, Bausewein, C., additional, Thomas, M., additional, Eschbach, C., additional, Schütte, W., additional, Blankenburg, T., additional, Steins, M., additional, Bischoff, H., additional, Schucher, B., additional, Rosseau, S., additional, Schütz, A., additional, Geiseler, J., additional, Kampf, S., additional, and Karg, O., additional

Published
2009
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44. Role of Sphingosine 1 Phosphate (S1P) in Murine Pneumococcal Pneumonia.

Author

Kube, SM, primary, Gutbier, B, additional, Hippenstiel, S, additional, Hocke, AC, additional, Haberberger, R, additional, Reppe, K, additional, Mueller, HC, additional, Schuette, H, additional, Rosseau, S, additional, Andratsch, M, additional, Mitchell, TJ, additional, Suttorp, N, additional, and Witzenrath, M, additional

Published
2009
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