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45 results on '"Rosenthal, Renate"'

1. Excavations at Maresha Subterranean Complex 169 : Final Report. Seasons 2000-2016

Author

Stern, Ian, Ambar-Armon, Einat, Ariel, Donald T., Evian, Shirley Ben-Dor, Cakmak, Lisa Ayla, Ecker, Avner, Erlich, Adi, Eshel, Esther, Finkielsztejn, Gerald, Ilan, David, Jackson-Tal, Ruth, Langlois, Michael, Perry-Gal, Lee, Polokoff, Ariel, Heginbottom-Rosenthal, Renate, Shamir, Orit, Ilan, David, General Editor, Stern, Ian, Ambar-Armon, Einat, Ariel, Donald T., Evian, Shirley Ben-Dor, Cakmak, Lisa Ayla, Ecker, Avner, Erlich, Adi, Eshel, Esther, Finkielsztejn, Gerald, Ilan, David, Jackson-Tal, Ruth, Langlois, Michael, Perry-Gal, Lee, Polokoff, Ariel, Heginbottom-Rosenthal, Renate, Shamir, Orit, and Ilan, David

Published
2019

2. The 'Shrinking' Clerkship: Characteristics and Length of Clerkships in Psychiatry Undergraduate Education

Author

Rosenthal, Renate H., Levine, Ruth E., and Carlson, David L.

Abstract

OBJECTIVE: The authors explored the time that is currently devoted to psychiatry clerkships to determine whether "shortened" clerkships differ in course director satisfaction and evaluation strategies. METHOD: An 18-item questionnaire was sent to 150 U.S. and Canadian clerkship directors. RESULTS: The return rate was 74% (111 questionnaires). Clerkship length ranged from 4 to 8 weeks, with 6 weeks being most common (49.5% of clerkships). Only 18.9% had clerkships lasting 8 full weeks. Shorter clerkships were more likely to rely on the NBME subject test, and less likely to rely on Objective Standardized Clinical Examinations (OSCEs) or oral examinations. Most clerkship directors (81.9%) felt their evaluation procedures reflected their clerkship objectives. Among those who did not or were not sure, a majority (77.7%) felt having too few weeks was among the causes, except for 8-week clerkship directors, who did not mention clerkship length as an issue. CONCLUSIONS: The number of clerkships having 2 full months devoted to psychiatry has decreased in recent years. Shorter clerkships rely heavily on the National Board of Medical Examiners (NBME) Subject Examination as an evaluation tool, testing for book knowledge rather than clinical skills.

Published
2005

7. Comparing high school and college students' leisure interests and stress ratings

Author

Chang, Alice F., Rosenthal, Ted L., Bryant, Elaine S., Rosenthal, Renate H., Heidlage, Rebecca M., and Fritzler, Bryan K.

Subjects
High school students -- Behavior, College students -- Behavior, Recreation research -- Reports, Stress in adolescence -- Research, Psychology and mental health
Abstract

We compared a large high school area sample with normative data from prior research with college students on the Leisure Interests Checklist (LIC) factor scales, and on the BAROMAS. Whether combined or separated by sex, the college sample displayed far more interest in the LIC activities than the high school students (all P << 0.001). On the BAROMAS, differences were more complex. The teenagers expressed more confidence about dismissing time pressures, sleeping soundly and finding time to do sports, but college students were more confident about falling asleep and sticking to set priorities. The high school data replicated the previous pattern of LIC x BAROMAS relationships, with most scales significantly inter-correlated within inventories, but mainly the sports scales covarying across the two inventories. Numerous differences between the sexes emerged from the high school student sample.

Published
1993

8. Assessing emotional distress at the internist's office

Author

Rosenthal, Ted L., Miller, Stephen T., Rosenthal, Renate H., Shadish, William R., Jr., Fogleman, Billye S., and Dismuke, S. Edwards

Subjects
Internal medicine -- Psychological aspects, Psychosomatic research -- Analysis, Symptomatology -- Research, Psychology and mental health
Abstract

At their first visits to a clinic, 102 outpatients rated the severity of their presenting complaint, of 12 possible body problems including 6 nonspecific symptoms, of a set of adjustment difficulties, and answered the Welsh A and the Beck Depression inventories. Then, a internist 'blind' to the foregoing answers performed a routine history and physical exam, afterward rating the patient for degree of organic and of psychosomatic involvement. Significant correlations were found between clinical judgments of psychosomatic involvement and patients' self-reported complaints on all assessment measures (smallest r = 0.25, P < 0.01). Substantial intercorrelations were found among the assessment measures, especially between Welsh A (Anxiety) and Beck Depression scores (r = 0.73).

Published
1991

9. Similarities and differences on five inventories among mood and anxiety disorder patients

Author

Rosenthal, Ted L., Downs, John M., Arheart, Kristopher L., Deal, Nancy, Downs, Anna F.D., and Rosenthal, Renate H.

Subjects
Psychodiagnostics -- Research, Affective disorders -- Research, Anxiety -- Research, Psychology and mental health
Abstract

The Eysenck Personality Questionnaire (EPQ), BAROMAS, Leisure Interests Checklist (LIC), Mental Health Inventory (MHI) and a one-page checklist of Body Problems were given to 128 outpatients with serious mood or anxiety disorders. Compared to normative data published on the first four devices, the combined patients were far 'sicker' in nearly all comparisons (P [is less than or equal to] 0.01). However, anxiety and mood patients did not differ on the EPQ, BAROMAS, or LIC. On Body Problems, strong contrasts emerged (P < 0.04), especially when 'fringe' cases were excluded (e.g. dysthymics from mood, and obsessives from anxiety disorder diagnose). Small anxiety subtype groups also differed (P < 0.05). On the MHI, both global and core groups of mood--especially unipolar (depressed)--patients differed from the anxiety disorders (P < 0.04).

Published
1991

12. NOTES AND NEWS

Author

Vitto, Fanny, Prausnitz, M.W., Rosenthal, Renate, Hershkovitz, Malka, Elgavish, Joseph, Stern, Ephraim, Paley, Samuel M., Porath, Yosef, Zohar, Mattanyahu, Shiloh, Yigal, O'Connell, Kevin G., Rose, D. Glenn, Seger, Joe D., Kloner, Amos, Cohen, Rudolph, and Dever, William G.

Published
1980

13. NOTES AND NEWS

Author

Wreschner, E., Lechevallier, Monique, Gilead, Y., Kloner, A., Meshel, Z., Sass, B., Cohen, R., Amiran, Ruth, Gofna, R., Alon, D., Beit-Arieh, Y., Kaplan, J., Kaplan, Haya, Dothan, M., Ussishkin, D., Ben-Tor, A., Aharoni, Y., Biran, A., Rose, D.G., Toombs, L.E., Meyers, E.M., Strange, J.F., Meyers, Carol L., Rosenthal, Renate, and Gichon, M.

Published
1975

18. Students' self-ratings of stress in medical school: a replication across 20 months

Author

Rosenthal, Ted L., Rosenthal, Renate H., and Edwards, Neil B.

Subjects
Medical students -- Psychological aspects, Stress (Psychology) -- Research, Psychology and mental health
Abstract

We replicated the essential reuslts of a prior study on the capacity of the BAROMAS scales to reflect stress in medical school as perceived by students. As before, subjective stress was high at the start of medical school, and when facing the exams prerequisite to entry into clinical clerkships. On most measures, stress was lowest when the second year began (i.e. after having passed the first). Once again, most test-retest reliabilities (significant rs ranged from 0.24 to 0.66 for confidence ratings at 12- and 20-months after entry) were moderate.

Published
1990

20. Partial Meal Replacement Plan and Quality of the Diet at 1 Year: Action for Health in Diabetes (Look AHEAD) Trial

Author

Raynor, Hollie A., primary, Anderson, Andrea M., additional, Miller, Gary D., additional, Reeves, Rebecca, additional, Delahanty, Linda M., additional, Vitolins, Mara Z., additional, Harper, Patricia, additional, Mobley, Connie, additional, Konersman, Kati, additional, Mayer-Davis, Elizabeth, additional, Brancati, Frederick L., additional, Honas, Jeff, additional, Cheskin, Lawrence, additional, Clark, Jeanne M., additional, Stewart, Kerry, additional, Rubin, Richard, additional, Charleston, Jeanne, additional, Horak, Kathy, additional, Bray, George A., additional, Rau, Kristi, additional, Strate, Allison, additional, Armand, Brandi, additional, Greenway, Frank L., additional, Ryan, Donna H., additional, Williamson, Donald, additional, Bachand, Amy, additional, Begnaud, Michelle, additional, Berhard, Betsy, additional, Caderette, Elizabeth, additional, Cerniauskas, Barbara, additional, Creel, David, additional, Crow, Diane, additional, Guay, Helen, additional, Kora, Nancy, additional, LaFleur, Kelly, additional, Landry, Kim, additional, Lingle, Missy, additional, Perault, Jennifer, additional, Shipp, Mandy, additional, Smith, Marisa, additional, Tucker, Elizabeth, additional, Lewis, Cora E., additional, Thomas, Sheikilya, additional, Safford, Monika, additional, DiLillo, Vicki, additional, Bragg, Charlotte, additional, Dobelstein, Amy, additional, Gilbert, Stacey, additional, Glasser, Stephen, additional, Hannum, Sara, additional, Hubbell, Anne, additional, Jones, Jennifer, additional, Lee, DeLavallade, additional, Luketic, Ruth, additional, Marshall, Karen, additional, Oden, L. Christie, additional, Raines, Janet, additional, Roche, Cathy, additional, Truman, Janet, additional, Webb, Nita, additional, Wrenn, Audrey, additional, Nathan, David M., additional, Turgeon, Heather, additional, Schumann, Kristina, additional, Cagliero, Enrico, additional, Delahanty, Linda, additional, Hayward, Kathryn, additional, Anderson, Ellen, additional, Bissett, Laurie, additional, Ginsburg, Richard, additional, Goldman, Valerie, additional, Harlan, Virginia, additional, McKitrick, Charles, additional, McNamara, Alan, additional, Michel, Theresa, additional, Poulos, Alexi, additional, Steiner, Barbara, additional, Tosch, Joclyn, additional, Horton, Edward S., additional, Jackson, Sharon D., additional, Hamdy, Osama, additional, Caballero, A. Enrique, additional, Bain, Sarah, additional, Bovaird, Elizabeth, additional, Goebel-Fabbri, Ann, additional, Lambert, Lori, additional, Ledbury, Sarah, additional, Malloy, Maureen, additional, Ovalle, Kerry, additional, Blackburn, George, additional, Mantzoros, Christos, additional, Day, Kristinia, additional, McNamara, Ann, additional, Hill, James O., additional, Miller, Marsha, additional, Phillipp, JoAnn, additional, Schwartz, Robert, additional, Van Dorsten, Brent, additional, Regensteiner, Judith, additional, Benchekroun, Salma, additional, Coelho, Ligia, additional, Cohrs, Paulette, additional, Daeninck, Elizabeth, additional, Fields, Amy, additional, Green, Susan, additional, Hamilton, April, additional, Hamilton, Jere, additional, Leshchinskiy, Eugene, additional, McDermott, Michael, additional, Munkwitz, Lindsey, additional, Rome, Loretta, additional, Wallace, Kristin, additional, Worley, Terra, additional, Foreyt, John P., additional, Reeves, Rebecca S., additional, Pownall, Henry, additional, Balasubramanyam, Ashok, additional, Jones, Peter, additional, Burrington, Michele, additional, Chen, Chu-Huang, additional, Clark, Allyson, additional, Gee, Molly, additional, Griggs, Sharon, additional, Hamilton, Michelle, additional, Holley, Veronica, additional, Joseph, Jayne, additional, Pace, Patricia, additional, Palencia, Julieta, additional, Satterwhite, Olga, additional, Schmidt, Jennifer, additional, Volding, Devin, additional, White, Carolyn, additional, Saad, Mohammed F., additional, Ghazarian, Siran, additional, Chiu, Ken C., additional, Botrous, Medhat, additional, Chan, Michelle, additional, Perpetua, Magpuri, additional, Johnson, Karen C., additional, Gresham, Carolyn, additional, Connelly, Stephanie, additional, Brewer, Amy, additional, Coday, Mace, additional, Jones, Lisa, additional, Lichtermann, Lynne, additional, Vosburg, Shirley, additional, Taylor, J. Lee, additional, Kitabchi, Abbas E., additional, Lambeth, Helen, additional, Clark, Debra, additional, Crisler, Andrea, additional, Cunningham, Gracie, additional, Green, Donna, additional, Force, Debra, additional, Kores, Robert, additional, Rosenthal, Renate, additional, Smith, Elizabeth, additional, Sun, Maria, additional, Soberman, Judith, additional, Jeffery, Robert W., additional, Thorson, Carolyn, additional, Bantle, John P., additional, Redmon, J. Bruce, additional, Crow, Richard S., additional, Crow, Scott, additional, Raatz, Susan K., additional, Brelje, Kerrin, additional, Campbell, Carolyne, additional, Carls, Jeanne, additional, Carmean-Mihm, Tara, additional, Finch, Emily, additional, Fox, Anna, additional, Hoelscher, Elizabeth, additional, James, La Donna, additional, Maddy, Vicki A., additional, Ockenden, Therese, additional, Rice, Birgitta I., additional, Skarphol, Tricia, additional, Tucker, Ann D., additional, Voeller, Mary Susan, additional, Walcheck, Cara, additional, Pi-Sunyer, Xavier, additional, Patricio, Jennifer, additional, Heshka, Stanley, additional, Pal, Carmen, additional, Allen, Lynn, additional, Hirsch, Diane, additional, Holowaty, Mary Anne, additional, Wadden, Thomas A., additional, Maschak-Carey, Barbara J., additional, Schwartz, Stanley, additional, Foster, Gary D., additional, Berkowitz, Robert I., additional, Glick, Henry, additional, Kumanyika, Shiriki K., additional, Brock, Johanna, additional, Chomentowski, Helen, additional, Clark, Vicki, additional, Crerand, Canice, additional, Davenport, Renee, additional, Diamond, Andrea, additional, Fabricatore, Anthony, additional, Hesson, Louise, additional, Krauthamer-Ewing, Stephanie, additional, Kuehnel, Robert, additional, Lipschutz, Patricia, additional, Mullen, Monica, additional, Womble, Leslie, additional, Iqbal, Nayyar, additional, Kelley, David E., additional, Wesche-Thobaben, Jacqueline, additional, Kuller, Lewis, additional, Kriska, Andrea, additional, Bonk, Janet, additional, Danchenko, Rebecca, additional, Edmundowicz, Daniel, additional, Klem, Mary L., additional, Yamamoto, Monica E., additional, Elnyczky, Barb, additional, Grove, George A., additional, Harper, Pat, additional, Krulia, Janet, additional, Mancino, Juliet, additional, Mathews, Anne, additional, Murray, Tracey Y., additional, Ritchea, Joan R., additional, Rush, Jennifer, additional, Vujevich, Karen, additional, Wolf, Donna, additional, Wing, Rena R., additional, Bright, Renee, additional, Pera, Vincent, additional, Jakicic, John, additional, Tate, Deborah, additional, Gorin, Amy, additional, Gallagher, Kara, additional, Bach, Amy, additional, Bancroft, Barbara, additional, Bertorelli, Anna, additional, Carey, Richard, additional, Charron, Tatum, additional, Chenot, Heather, additional, Chula-Maguire, Kimberley, additional, Coward, Pamela, additional, Cronkite, Lisa, additional, Currin, Julie, additional, Daly, Maureen, additional, Egan, Caitlin, additional, Ferguson, Erica, additional, Foss, Linda, additional, Gauvin, Jennifer, additional, Kieffer, Don, additional, Lessard, Lauren, additional, Maier, Deborah, additional, Massaro, J.P., additional, Monk, Tammy, additional, Nicholson, Rob, additional, Patterson, Erin, additional, Phelan, Suzanne, additional, Raynor, Hollie, additional, Raynor, Douglas, additional, Robinson, Natalie, additional, Robles, Deborah, additional, Tavares, Jane, additional, Haffner, Steven M., additional, Montez, Maria G., additional, Lorenzo, Carlos, additional, Kahn, Steven E., additional, Montgomery, Brenda, additional, Knopp, Robert, additional, Lipkin, Edward, additional, Maciejewski, Matthew L., additional, Trence, Dace, additional, Barrett, Terry, additional, Bartell, Joli, additional, Greenberg, Diane, additional, Murillo, Anne, additional, Richmond, Betty Ann, additional, Thomas, April, additional, Knowler, William C., additional, Bolin, Paula, additional, Killean, Tina, additional, Manus, Cathy, additional, Krakoff, Jonathan, additional, Curtis, Jeffrey M., additional, Glass, Justin, additional, Michaels, Sara, additional, Bennett, Peter H., additional, Morgan, Tina, additional, Begay, Shandiin, additional, Fallis, Bernadita, additional, Hermes, Jeanette, additional, Hollowbreast, Diane F., additional, Johnson, Ruby, additional, Meacham, Maria, additional, Nelson, Julie, additional, Percy, Carol, additional, Poorthunder, Patricia, additional, Sangster, Sandra, additional, Scurlock, Nancy, additional, Shovestull, Leigh A., additional, Smiley, Janelia, additional, Toledo, Katie, additional, Tomchee, Christina, additional, Tonemah, Darryl, additional, Peters, Anne, additional, Ruelas, Valerie, additional, Sengardi, Siran Ghazarian, additional, Graves, Kathryn, additional, Serafin-Dokhan, Sara, additional, Espeland, Mark A., additional, Bahnson, Judy L., additional, Wagenknecht, Lynne, additional, Reboussin, David, additional, Rejeski, W. Jack, additional, Bertoni, Alain, additional, Lang, Wei, additional, Miller, Gary, additional, Lefkowitz, David, additional, Reynolds, Patrick S., additional, Ribisl, Paul, additional, Vitolins, Mara, additional, Booth, Michael, additional, Dotson, Kathy M., additional, Hodges, Amelia, additional, Williams, Carrie C., additional, Barnes, Jerry M., additional, Feeney, Patricia A., additional, Griffin, Jason, additional, Harvin, Lea, additional, Herman, William, additional, Hogan, Patricia, additional, Jaramillo, Sarah, additional, King, Mark, additional, Lane, Kathy, additional, Neiberg, Rebecca, additional, Ruggiero, Andrea, additional, Speas, Christian, additional, Walkup, Michael P., additional, Wall, Karen, additional, Ward, Michelle, additional, West, Delia S., additional, Windham, Terri, additional, Nevitt, Michael, additional, Ewing, Susan, additional, Hayashi, Cynthia, additional, Maeda, Jason, additional, Palermo, Lisa, additional, Rahorst, Michaela, additional, Schwartz, Ann, additional, Shepherd, John, additional, Marcovina, Santica M., additional, Strylewicz, Greg, additional, Prineas, Ronald J., additional, Alexander, Teresa, additional, Billings, Lisa, additional, Campbell, Charles, additional, Hall, Sharon, additional, Hensley, Susan, additional, Li, Yabing, additional, Zhang, Zhu-Ming, additional, Mayer-Davis, Elizabeth J., additional, Moran, Robert, additional, Foushee, Richard, additional, Hall, Nancy J., additional, Harrison, Barbara, additional, Hubbard, Van S., additional, Yanovski, Susan Z., additional, Cooper, Lawton S., additional, Cutler, Jeffrey, additional, Obarzanek, Eva, additional, Gregg, Edward W., additional, Williamson, David F., additional, and Zhang, Ping, additional

Published
2015
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21. Student assessment of psychiatry clinical simulation teaching modules

Author

Foster, Adriana, primary, Johnson, Teresa, additional, Liu, Howard, additional, Cluver, Jeffrey, additional, Johnson, Sarah, additional, Neumann, Chelsea, additional, Marcangelo, Michael, additional, Rosenthal, Renate, additional, Ton, Hendry, additional, Davidson, Bernard, additional, and Klapheke, Martin, additional

Published
2014
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27. Psychogenic Vomiting: A Review.

Author

Wruble, Lawrence D., Rosenthal, Renate H., and Webb Jr., William L.

Subjects
VOMITING, EATING disorders, ANXIETY, PSYCHOLOGY of the sick, GASTROENTEROLOGISTS
Abstract

Herein, an effort is made to clarify and define the characteristics of nonorganic or psychogenic vomiting. Detailed discussion of the clinical and psychological aspects of the disorders comprising this syndrome is presented. The role of anxiety in several eating disorders is stressed. Finally, the central role of the gastroenterologist rather than the psychiatrist is emphasized in treating these disorders. [ABSTRACT FROM AUTHOR]

Published
1982

30. Characterological Depressions: Clinical and Sleep EEG Findings Separating 'Subaffective Dysthymias' From 'Character Spectrum Disorders'

Author

Akiskal, Hagop S., Rosenthal, Ted L., Haykal, Radwan F., Lemmi, Helio, Rosenthal, Renate H., and Scott-Strauss, Alice

Abstract

• Early-onset characterological depressions are distinguished from late-onset chronic depressions that complicate the longterm course of unipolar and nonaffective illnesses. In turn, characterological depressions are divisible into at least two subtypes: (1) "Subaffective dysthymias" have even sex distribution, are often complicated by superimposed depressive episodes, rapid eye movement latency is shortened, and they tend to respond to tricyclics or lithium carbonate. In brief, they share many features of primary affective illness. (2) "Character spectrum disorders," by contrast, represent a heterogeneous mixture of personality disorders with inconstant depressive features, are more common in women, are often complicated by alcohol and drug abuse, and outcome tends to be unfavorable.

Published
1980
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31. Differentiation of Primary Affective Illness From Situational, Symptomatic, and Secondary Depressions

Author

Akiskal, Hagop S., Rosenthal, Renate H., Rosenthal, Ted L., Kashgarian, Mark, Khani, Munir K., and Puzantian, Vahe R.

Abstract

• Analysis of family history and antidepressant drug response variables of 100 "neurotic" depressives followed up prospectively over three to four years disclosed that primary depressions (unipolar and bipolar) could be distinguished from nonprimary cases by (1) the early occurrence of "pharmacological-hypomania;" (2) family history of bipolar illness; (3) family history for affective disorder in two or three consecutive generations, especially when "loaded." Although each of these variables alone occurred in only one fifth to one third of the primary group, they individually displayed better than 95% specificity for it. Thus, the confidence with which the diagnosis of primary affective illness could be made in the presence of any of these variables ranged from 88% to 100%. These findings argue for considering such nonsymptomatological variables for their potential in strengthening the phenomenologic diagnostic criteria for depressive illness.

Published
1979
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32. Probability Matching through Vicarious and Direct Experience

Author

Rosenthal, Renate H., White, Glenn M., and Rosenthal, Ted L.

Abstract

Vicarious and direct exposure were compared on a binary probability learning task, using 204 volunteers. Control subjects performed 150 trials alone. Experimentals were run in dyads: the first subject performed 75 trials while his partner observed; then the observer performed individually on 75 trials. Observation established responding closely comparable to direct participation, and all groups were able to estimate closely the relative event probabilities. An associative view of probability learning was questioned because subjects approached the task with a strong problem-solving set, seeking order in the random sequences despite task directions to the contrary.

Published
1975
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44. Student assessment of psychiatry clinical simulation teaching modules.

Author

Foster, Adriana, Johnson, Teresa, Liu, Howard, Cluver, Jeffrey, Johnson, Sarah, Neumann, Chelsea, Marcangelo, Michael, Rosenthal, Renate, Ton, Hendry, Davidson, Bernard, and Klapheke, Martin

Subjects
ADULTS, HIGHER education, MEDICAL cooperation, PSYCHIATRY, QUESTIONNAIRES, RESEARCH, SATISFACTION, SCALE analysis (Psychology), STATISTICS, STUDENTS, DATA analysis, TEACHING methods, DESCRIPTIVE statistics
Abstract

A letter to the editor is presented discussing the authors' work developing a computer-based clinical simulation for psychiatry education.

Published
2015
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45. Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial.

Author

Rubin RR, Wadden TA, Bahnson JL, Blackburn GL, Brancati FL, Bray GA, Coday M, Crow SJ, Curtis JM, Dutton G, Egan C, Evans M, Ewing L, Faulconbridge L, Foreyt J, Gaussoin SA, Gregg EW, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Knowler WC, Lang W, Lewis CE, Montez MG, Murillo A, Nathan DM, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Rejeski WJ, Rosenthal RH, Ruelas V, Toledo K, Van Dorsten B, Vitolins M, Williamson D, Wing RR, Yanovski SZ, and Zhang P

Subjects
Antidepressive Agents therapeutic use, Depression etiology, Depression psychology, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 therapy, Female, Humans, Male, Middle Aged, Obesity physiopathology, Obesity psychology, Obesity therapy, Overweight physiopathology, Overweight psychology, Overweight therapy, Surveys and Questionnaires, Treatment Outcome, Weight Loss physiology, Depression prevention & control, Diabetes Mellitus, Type 2 psychology, Life Style, Quality of Life
Abstract

Objective: We examined the effects of an intensive lifestyle intervention (ILI), compared with a diabetes support and education (DSE) control intervention, on long-term changes in depression symptoms, antidepressant medication (ADM) use, and health-related quality of life (HRQoL) in overweight/obese individuals with type 2 diabetes., Research Design and Methods: Look AHEAD was a multisite randomized controlled trial of 5,145 overweight/obese participants assigned to ILI (designed to produce weight loss) or DSE and followed for a median of 9.6 years. The Beck Depression Inventory (BDI) was administered at baseline, annually at years 1-4, and again at year 8. Mean BDI scores and incidence of BDI scores ≥10, indicative of likely mild or greater depression, were examined. Annually through year 10, participants reported their ADM use and completed the Medical Outcomes Study Short Form 36 (SF-36) questionnaire, which yields physical component summary (PCS) and mental component summary (MCS) scores., Results: ILI significantly reduced the incidence of mild or greater depression symptoms (BDI scores ≥10) compared with DSE (hazard ratio [HR] = 0.85; 95% CI 0.75-0.97; P = 0.0145). Although SF-36 PCS scores worsened over time in both groups, ILI participants reported better physical function than DSE throughout the first 8 years (all P values <0.01). There were no significant differences between treatment arms in the proportion of participants who used ADMs or in SF-36 MCS scores., Conclusions: ILI for overweight/obese patients with type 2 diabetes may reduce the risk of developing clinically significant symptoms of depression and preserve physical HRQoL. These findings should be considered when evaluating the potential benefits of ILIs., (© 2014 by the American Diabetes Association.)

Published
2014
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