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1. A Pilot Study Comparing Aortic Valve Area Estimates Derived from Fick Cardiac Output with Estimates Based on Cheetah-NICOM Cardiac Output.

Author

Mitrev, L., Helmond, N. van, Kaddissi, G., Awad, A., Patel, K., Aji, J., Ogbara, J., Rafeq, Z., Nagubandi, V., Orr, D., Gaughan, J., Rosenbloom, M., Mitrev, L., Helmond, N. van, Kaddissi, G., Awad, A., Patel, K., Aji, J., Ogbara, J., Rafeq, Z., Nagubandi, V., Orr, D., Gaughan, J., and Rosenbloom, M.

Abstract

Contains fulltext : 221539.pdf (publisher's version ) (Open Access), Cardiac output during cardiac catheterization is often estimated using the modified Fick method (CO(Fick)). In this proof-of-concept, prospective non-randomized study carried out in a single academic healthcare centre, we examined whether replacing CO(Fick) in the Gorlin formula with Cheetah-NICOM monitor cardiac output (CO(Cheetah)) could produce an accurate and precise estimate of aortic valve area in patients with severe aortic stenosis. In twenty-six subjects, CO(Fick) and CO(Cheetah) were obtained concurrently. A spot and 3-minute running average of CO(Cheetah) was used. Bland and Altman analysis was used to derive bias, 95% limits of agreement (LOA) and confidence intervals (CI). The mean difference (bias) between AVA(Cheetah) (average) and AVA(Fick) was 0.11 cm(2) and the 95% LOA were ±0.42 cm(2). The 95% CI of the bias was 0.02-0.2 cm(2). The bias and 95% LOA of AVA(Cheetah) (spot value) were 0.14 ± 0.42cm(2), with a 95% CI of 0.06-0.23 cm(2). No proportional bias was present. AVA(Cheetah) thus appears to be a reasonably accurate measure of AVA in patients with severe aortic stenosis compared to AVA(Fick) measured using a modified Fick CO. However, the limits of agreement were not narrow enough to consider AVA(Cheetah) and AVA(Fick) interchangeable.

Published
2020

7. Abstracts

Author

Mutch, W. A. C., White, I. W. C., Donen, N., Thomson, I. R., Rosenbloom, M., Cheang, M., West, M., Bryson, Greg, Mundi, Christina, Dupuis, Jean-Yves, Bourke, Michael, McDonagh, Paul, Curran, Michael, Kitts, John, Wynands, J. Earl, Carr, Alison S., Hartley, Elizabeth J., Holtby, Helen M., Cox, Peter, Macpherson, Bruce A., Baker, James E., Baker, Andrew J., Mazer, C. David, Peniston, C., David, T., Cheng, D. C. H., Karski, J., Asokumar, B., Carroll, J., Nierenberg, H., Roger, S., Sandier, A. N., Tong, J., Feindel, C. M., Boylan, J. F., Teasdale, S. J., Boylan, J., Harley, P., Froelich, Jennifer E., Archer, David P., Ewen, Alastair, Samanani, Naaznin, Roth, Sheldon H., Hall, Richard I., Neumeister, Michael, Dawe, Gwen, Cody, Cathy, O’Brien, Randy, Shields-Thomson, Jan, LeDez, Kenneth M., Penney, Catherine, Snedden, Walter, Tucker, John, Fauvel, Nicolas, Glavinovic, Mladen, Donati, François, Backman, S. B., Stein, R. D., Polosa, C., Abdallah, C., Gal, S., Clark, A. John, Doig, George A., Gondocz, Tunde, Peter, E. A., Lopez, A., Mathieu, A., Couture, Pierre, Boudreault, Daniel, Derouin, Marc, Allard, Martin, Blaise, Gilbert, Girard, Dominique, Knill, Richard L., Novick, Teresa, Vandervoort, Margaret K., Chung, Frances, Paramanathar, Shantha, Parikh, Smita, Cruise, Charles, Michaloliakou, Christina, Dusek, Brenda, Rose, D. K., Cohen, M. M., DeBoer, D., Shorten, George, Cutz, Earnest, Lerman, Jerrold, Dolovich, Myrna, Crosby, Edward T., Cirone, Robert, Reid, Dennis, Lind, Joanne, Armstrong, Melanie, Doyle, Wanda, Halpern, S., Glanc, P., Myhr, T., Ryan, M -L., Fong, K., Amankwah, K., Ohlsson, A., Preston, R., Petras, Andor, Jacka, Michael J., Milne, Brian, Nakatsu, Kanji, Pancham, S., Smith, Graeme, Duggal, Kush N., Douglas, M. Joanne, Merrick, Pamela M., Blew, Philip, Miller, Donald, Martineau, Raymond, Hull, Kathryn, Baron, C. M., Kowalskl, S., Greengrass, R., Horan, T., Unruh, H., Baron, C. L., Cruchley, Patricia M., Nakajima, K., Sugiura, Y., Goto, Y., Takakura, K., Harada, J., Lee, Robert M. K. W., Fargas-Babjak, Angelica M., Ni, Jin, Werstiuk, Eva S., Woo, Joseph, Morison, David H., McHugh, Michael D., Pappius, Hanna M., Ishihara, Hironori, Shimodate, Yuki, Koh, Hiroaki, Matsuki, Akitomo, Mclntyre, John W. R., Bergeron, Pierre, DeLima, Lulz G. R., Dupuls, Jean-Yves, Enns, James, Murkin, J. M., McKenzie, F. N., White, S., Shannon, N. A., Dobkowski, Wojciech B., Kutt, Judy L., Mezon, Bernard J., Grant, David R., Wall, William J., Doblar, Dennis D., Lim, Yong C., Frenette, Luc, Ronderos, Jaime R., Poplawski, Steve, Ranjan, Dinesh, Dubé, L., Obbergh, L. Van, Francoeur, M., Blouin, C., Carrier, R., Doblar, D., Ronderos, J., Singer, D., Cox, J., Gosdin, B., Boatwright, M., Smith, Charles E., Rovner, Aleksandr, Botero, Carlos, Holbrook, Curt, Patel, Nileshkumar, Pinchak, Alfred, Pinchak, Alfred C., Kao, Yin James, Thio, Andrew, Barker, Steven J., Sullivan, Patrick, Posner, Matthew, Cole, C. William, Lindsay, Patty, Langevin, Paul B., Gulig, Paul A., Gravenstein, N., Wong, David T., Gomez, Manuel, McGuire, Glenn P., Byrick, Robert J., Sharma, Shared K., Carmicheal, Frederick J., Montanera, Walter J., Sharma, Sharad, Yee, D. A., Naser, Basem I., Bryson, G. L., Kitts, J. B., Miller, D. R., Martineau, R. J., Curran, M. J., Bragg, P. R., Karski, Jacek M., Cheng, Davy, Bailey, Kevin, Levytam, S., Arellano, R., Katz, J., Doyle, J., Sosis, Mitchel B., Blazek, William, Plourde, G., Malik, A., Peddle, Tammy, Au, James, Sloan, Jeffrey, Cleland, Mark, Hancock, Donald E., Patel, Nilesh, Costello, Frank, Patterson, Louise, Yamashita, Masao, Kondo, Tsukasa, Graham, M. R., Thiessen, D., Vener, David F., Long, Thomas, Marion, S., Steward, D. J., Braverman, Berton, Levine, Mark, Yentis, Steve, Bachman, Catherine R., Kopelow, Murray, McNeill, Ann, Graham, R., Froese, Norbert, Patel, Leena, Reimer, Heinz, Swartz, Jo, Ullyot, Suzanne, Wong, Harley, Markakis, Maria A., Siklch, Nancy, Goranson, Blair D., Lang, Scott A., Stockwell, Martin J., Cujec, Bibiana, Yip, Raymond W., Southeriand, Lucy C., Vet, Tanya Duke B., Gollagher, Jeisane M., Crone, Lesley-Ann, Ferguson, James G., Litwin, Demetrius, Bertlik, Maria, Orser, Beverley A., Yang, Lu-Wang, MacDonald, John F., Morris, Gary F., Gore-Hickman, Wendy L., Zamora, J. E., Rosaeg, O. P., Lindsay, M. P., Crossan, M. L., Pattee, Carol, Adams, Michael, Koller, John P., Lavoie, Guy J., Rigal, Wynn M., Taylor, Dylan A., Grace, Michael G., Flnegan, Barry A., Hawkes, Christopher, Hopkins, Harry, Tierney, Michael, Drover, David R., Whatley, Gordon, Knox, J. W. Donald, Rausa, Jarmila, El-Beheiry, Hossam, Seegobin, Ronald, Hirst, Georgia C., Dust, William N., Cassidy, J. David, Boisvert, D., Braden, H., Halperin, M. L., Cheema-Dhadli, S., McKnight, D. J., Singer, W., Elwood, Thomas, Huchcroft, Shirley, MacAdams, Charles, Farran, R. Peter, Goresky, Gerald, LaLande, Phillip, Lacroix, Gilles, Lessard, Martin, Trépanier, Claude, van Vlymen, Janet M., Parlow, Joel L., Ibebunjo, Chikwendu, Morscher, Arnold H., Gordon, Gregory J., Grocott, H. P., Belo, Susan E., Koutsoukos, Georgios, Belo, Susan, Smith, David, Henderson, Sarah, Gelb, Adriene, Kantor, G., Badner, N. H., Komar, W. E., Bhandari, R., Cuillerier, D., Dobkowski, W., Smith, M. H., Vannelli, A. N., Wharton, Sean, Tierney, Mike, Redmond, E., Reddy, E., Gray, A., Flynn, J., Bourne, R. B., Rorabeck, C. H., MacDonald, S. J., Doyle, J. A., Newton, Peter T., Moote, Carol A., Joiner, R., Glynn, M. F. X., Zulys, Vytas, Hennessy, M., Winton, T., Demajo, W., McKay, William P. S., Gregson, Peter H., McKay, Benjamin W. S., Militzer, Julio, Hollebone, Eric, Yee, Raymond, Klein, George, Garnett, R. L., Conway, J., Ralley, F. E., Robbins, G. R., Brown, James E., Frei, J. V., Podufal, Edward, Snow, Norman J., Chavez, Altagracia M., Kramer, Richard P., Mickle, D., Tweed, William A., Shrestha, Bisharad M., Basnyat, Narendra B., Lekhak, Bhawan D., O’Leary, Susan D., Maryniak, J. K., Tucker, John H., Guest, Cameron B., Mullen, J. Brendan, Kay, J. Colin, Wigglesworth, Dan F., Goodarzi, Mashallah, Shier, Nicte Ha, Ogden, John A., Hung, O. R., Pytka, S., Murphy, M. F., Martin, B., and Stewart, R. D.

Published
1994
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8. Brain CT changes in alcoholics: effects of age and alcohol consumption.

Author

Pfefferbaum, A, Rosenbloom, M, Crusan, K, and Jernigan, TL

Subjects
Cerebral Ventricles, Humans, Substance-Related Disorders, Alcoholism, Serum Albumin, Tomography, X-Ray Computed, Liver Function Tests, Erythrocyte Indices, Hematocrit, Risk Factors, Alcohol Drinking, Neuropsychological Tests, Age Factors, Adult, Aged, Aged, 80 and over, Middle Aged, Substance Abuse, Clinical Sciences, Psychology, Neurosciences
Abstract

A computerized tomographic (CT) brain scan and assessments of lifetime alcohol consumption, body size, and cognitive performance were performed in 37 male alcoholics, aged 26-62 years. Hematocrit and mean corpuscular volume (MCV) were also measured. CT data were analyzed using a semiautomated scoring system yielding measures of percentage of fluid at the ventricles and cortical sulci. Normative brain CT data from 57 community controls spanning the adult age range allowed Z-score assessment of deviation from age norms for each alcoholic. Across the entire group, alcoholics had significantly enlarged ventricles and sulci for their age. Enlargement at both sites correlated significantly with lifetime alcohol consumption. Sulcal enlargement in alcoholics was found across all ages. In contrast, ventricular enlargement was apparent only in older alcoholics and became increasingly exaggerated with age. Measures of body size, hematocrit, and MCV correlated with ventricular but not sulcal enlargement, suggesting that nutritional factors play a role in ventricular enlargement. Associations between neuropsychological performance and CT changes or alcohol consumption were less pronounced and at times counterintuitive. The findings support a modest dose-effect relationship between ethanol exposure and changes in brain morphology, and suggest that ventricles and sulci show a different time course of response. The role of nutritional status needs to be more closely investigated.

Published
1988

9. Abstracts

Author

Michèle, Saiah, Alain, Borgeat, Oliver, Wilder-Smith, Hung, Orlando R., Hope, Charles E., Laney, Geoffrey, Whynot, Sara C., Coonan, Thomas J., Malloy, David S., Patterson, S., Gelb, A., Manninen, P., Strum, D., Glosten, B., Spellman, M. J., Eger, E. I., Craen, R. A., Gelb, A. W., Murkin, J. M., Chong, K. Y., Penning, D. H., El-Behairy, H., Brien, J. F., Coh, J. W., Arellano, R., Correa, J., Fedorko, L., Arellano, R., Liu, Z., Boylan, J. F., Sandler, A. N., Nierenberg, H., Sheiner, P. A., Greig, P. D., O’Leary, G. M., Teasdale, S. J., Glynn, M. F. X., Orser, B. A., Wang, L. -Y., MacDonald, J. F., Loomis, C. W., Arunachalam, K. D., Vyas, D., Milne, B., Gagnon, Daniel, Lavoie, Josée, Dupuis, Jean-Yves, Miller, D. R., Martineau, R. J., Greenway, D., Olivaris, L., Hull, K., Tierney, R. N. M., Wynands, J. E., Martineau, R., St-Jean, B., Kitts, J., Miller, D., Lindsay, P., Curran, M., Allen, G. C., Crossan, M. L., Wise, Richard, Donati, François, Bevan, David R., Hardy, J. F., Desroches, J., Perrault, J., Carrier, M., Robitaille, D., Ansley, D. M., O’Connor, J. P., Dolman, J., Townsend, G. E., Ricci, D., Liepert, D. J., Browne, P. M., Hertz, T., Rooney, M., Yip, R. W., Code, W., Phillips, A. A., McLean, R. F., Devitt, J. H., Harrington, E. M., Byrick, R. J., Wong, P. Y., Wigglesworth, D., Kay, J. C., Sinclair, L. A., Koch, J. P., Deemar, K. A., Christakis, G. K., Belo, S., Angle, P., Cheng, D., Boylan, J., Sandler, A., Feindel, C., Carmichael, F., Boylen, P., Boylen, P., DeLima, L. G. R., Nathan, H. J., Hynes, M. S., Bourke, M. E., Russell, G. N., Seyone C., Chung F., Chartrand, Daniel, Roux, Lucie, Dain, S. L., Smith, B. D., Webster, A. C., Wigglesworth, D. F., Rose, D. K., Caskennette, G., Mechetuk, C., Doyle, D. John, DeMajo, Wilfred, van den Bosch, Frank, Lee, Mark, McClenaghan, K. M., Mazer, C. D., Preston, R., Crosby, E. T., Kotarba, D., Dudas, H., Elliott, R. D., Enns, J., Manninen, P. H., Farrar, J. K., Huzyka, David L., Lin, L. Philip, Fossey, Susan, Finucane, Brendan T., Stockwell, M., Lozanoff, S., Lang, S., Hyssen, J., Campbell, D. C., Douglas, M. J., Pavy, T. J. G., Flanagan, M. L., McMorland, G. H., Bands, Colin, Ffaracs, Ch. B., Lipsett, Catherine, Drover, David, Stafford-Smith, Mark, Stevens, Sarah, Shields, Kate, MacSween, Michael J., McAllister, J. D., Morley-Forster, P. K., White, A. K., Taylor, M. D., Vandenberghe, H. M., Knoppert, D., Reimer, H., Duke, P. C., Kehler, C. H., Kepron, M. W., Taraska, V. A., Carstoniu, J., Norman, P., Katz, J., Hannallah, Medhat, Cooney, C. M., Lyons, J. B., Hennigan, A., Blunnie, W. P., Moriarty, D. C., Dobkowski, W. B., Prato, F. S., Shannon, N. A., Drost, D. J., Arya, B., Wills, J. M., Bond, D., Morley-Forester, P., JB, Mullen, Spahr-Schopfer, I., Lerman, J., Cutz, E., Dolovich, M., Kowalski, S., Ong, B., Bell, D., Ostryzniuk, T., Serrette, C., Wasylak, T., Coke, S., Tsuda, Takako, Nakagawa, Takashi, Mabuchi, Norifumi, Ando, Hiroshi, Nishida, Osamu, Azami, Takafumi, Katsuya, Hirotada, Goto, Yukio, Searle, N., Roy, M., R. R. T., Smith, Charles E., Pinchak, Alfred C., Hagen, Joan F., Hancock, Donald, Krassioukov, Andrei V., Weaver, Lynne C., Sutton, I. R., Mutch, W. A. C., Teskey, J. M., Thomson, I. R., Rosenbloom, M., Thiessen, D., Teasdale S., Corbin H., Graham, M. R., Lang, S. A., Chang, P., Gerard, M., Tetzlaff, J. E., Walsh, M., Yoon, H., Warriner, Brian, Fancourt-Smith, Peter, McEwen, Jim, Crane, Judy, Badner, N. H., Bhandari, R., Komar, W. E., Ganapathy, S., Warriner, C. B., McCormack, J. P., Levine, M., Glick, N., Chan, V. W. S., McQuestion, M., Gomez, M., Cruise, C., Evana, D., Shumka, D., Smyth, R. J., Graham, M., Halpenny, David, Goresky, Gerald V., Zaretski, J. Eldon, Kavanagh, B., Roger, S., Davies, A., Friedlander, M., Cohen M. M., Duncan P. G., Pope W. D. B., Biehl D., Merchant R., Tweed, W. A., Tessler, Michael J., Angle, Mark, Kleiman, Simcha, Kavanagh, B. P., Doak, G. J., Li, G., Hall, R. I., Sulliyan, J. A., Yee, I., Halpern, S., Pittini, R., Huh, C., Bryson, G. L., Gverzdys, R., Perreault, C., Ferland, L., Gobeil, F., Girard, D., Smyth, R., Asokumar, B., Glynn, M., Silveira, Sandra, Clark, Jeff, Milgram, Paul, Splinter, W. M., MacNeill, H. B., Ménard, E. A., Rhine, E. J., Roberts, D. J., Gould, G. M., Johnson, G. G., Quance, Daniel, Wiesel, Saul, Easdown, Jane, Truong, N. Tien, Miller, Normand, Sheiner, Nathan, Welborn, L., Norden, J., Hannallah, R., Broadman, L., Seiden, N., Iwai, M., Iwai, R., Horigome, H., Yamashita, M., Wood, Catherine E., Klassen, Kim, Kleinman, S., Yentis, S., Sikich, N., Yemen, T. A., Mascik, B., Nelson, W., Ghantous, H., Gandolfi, J., Wood, Gordon, Ali, Mohamed, Inman, Kevin, Karski, J. M., Carroll, J., Brooks, D., Oakley, P. A., Webster, P. M., Karski, J., Yao, T., Ivanov, J., Young, P., Carson, S., Weisel, R. D., Cooper, Richard M., Wong, David T., Wagner, Douglas P., Knaus, William A., Munshi, Charul A., Kampine, John P., Soutter, I. D., Mathieu, A., Gafni, A., Dauphin, A., Torsher, L., Tierney, M., Hopkins, H. S., Baylon, G. J., Peter, Elizabeth A., Bellhouse, C. P., Dore, Caroline, Rachwal, T. W., Lanigan, D. T., Yip, Raymond, Derdemezi, J. B., Britt, B. A., Withington, D. E., Reynolds, F., Patrick, A., Man, W., Searle, N. R., Ste-Marie, H., Kostash, Mark A., Johnston, Richard, Bailey, R. J., Sharpe, M. D., Woda, R. P., Haug, M., Slugg, P., Lockrem, J., Barnett, G., Finegan, B. A., Robertson, M., Taylor, D., Frost, G., Koshal, A., Rodney, Grant E., Reichert, Clayton C., O’Regan, Desmond N., Blackstock, Derek, Steward, David J., Wenstone, Richard, Harrington, Ellen, Wong, A., Braude, B., Fear, D., Bissonnette, B., Reid, Craig W., Hull, Kathryn A., Yogendran, S., McGuire, G., Chan, V., Hartley, E., Van Kessel, K., Weisel, R., Takla, N., Tremblay, N. A., Ralley, F. E., Ramsay, J. G., Robbins, G. R., Salevsky, F. C., Gandhi, S., Nimphius, N., Dionne, Bernard, Jodoin, Christian, Lorange, Michel, Lapointe, Alain, Hawboldt, Geoffrey, Volgyesi, G. A., Tousignant, Guy, Barnett, R., and Gallant, B.

Published
1992
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10. Abstracts

Author

Korzeniewski, P., Lang, S. A., Grant, R., Loader, C., Vaghadia, H., Wong, D., Waters, T., Merrick, P., Ali, M. J., Dobkowski, W., Cornelius, T., Hawkins, R., Varkey, G. P., Claffey, Liam, Plourde, Gilles, Trahan, Michel, Morris, Joan, Dean, Deanne M., Yamaguchi, Hiroshi, Harukuni, Izumi, Naito, Hiroshi, Chan, V. W. S., Mati, N., Seyone, C., Evans, D., Chung, F., Joffe, D., Plourde, G., Villemurc, C., Hong, M., Milne, B., Loomis, C., Jhamandas, K., Priddy, R., Archer, D., Tang, T., Sabourin, M., Samanini, N., Cuillerier, D. J., Schuben, Armin, Awad, Issam A., Perez-Trepichio, Alejandro D., Ebrahim, Zeyd Y., Bloomfield, Eric L., Zexu, Fang, Zhengnua, Gu, Qing, Zou, Balhua, Sung, Miller, D. R., Martineau, R. J., Wynands, J. E., Hill, J. D., Knill, R. L., Skinner, M. I., Novick, T. V., McLean, R. F., Kolton, M., Noble, W. H., Sullivan, P. J., Cheng, D. C. H., Chapman, K. R., Ong, D., Roraanelli, J., Smallman, Bettina, Nathan, Howard J., Murphy, J. T., Hall, R. I., Moffitt, E. A., Hudson, R. J., Pascoe, E. A., Anderson, B. A., Thomson, I. R., Kassum, D. A., Shanks, A., Rosenbloom, M., Sidi, A., Gehrig, T. R., Fool, J. M., Rush, W., Martin, A. J., Cooper, P. D., Maltby, J. R., Johnson, D., Hurst, T., Mayers, I., Wigglesworth, D. F., Rose, D. K., Kay, J. C., Mazer, C. D., Yang, H., Beattie, W. S., Doyle, D. John, Demajo, Wlifred, Comfort, V. Kim, Code, William E., Rooney, Michael E., Clark, F. J. S., Sutton, I. R., Mutch, W. A. C., Thomson, I. R., Teskey, J. M., Thiessen, O. B., Rosanbloom, M., Tang, T. K. K., Robblee, J. A., Nathan, H. J., Wynands, J. E., Eagle, C. J., Belenkle, I., Chan, K. L., Tyberg, J. V., Stockwell, M., Zintel, T., Gallagher, G., Kavanagh, B., Sandier, A., Lawson, S., Chung, F., Ong, D., Isabel, L., Trépanier, C. A., Campbell, David C., Randall, Thomas E., Growe, Gershon H., Scarth, Irene, Sawchuk C. W. T., Ong B., Unruh H., Horan T., Greengrass R., Mark, D., Kitts, J. B., Curran, M. J., Lindsay, P., Polis, T., Coté, Sylvain, Socci, Maria, Wiesel, Saul, Conway, J. B., Seyone, C., Goldberg, J., Chung, F., Rose, D. Keith, Cohen, Marsha M., Rogers, Kent H., Duncan P. G., Pope W. D. B., Tweed W. A., Biehl D., Novick, T. V., Skinner, M. I., Mathieu, Alix, Villeneuve, Edith, Goldsmith, Charles H., Allen, Gregory C., Smith, Charles E., Pinchak, Alfred C., Hagen, Joan F., Hudson, J. C., Gennings, C., Tyler, B. L., Keenan, R. L., Chung, F., Seyone, C., Matl, N., Ong, D., Powell, P., Tessler, M. J., Kleiman, S. J., Wiesel, S., Tetzlaff, John E., Yoon, Helen J., Baird, Bruce, Walsh, Michael, Hondorp, Gregory, Wassef, Medhat R., Munshi, C., Brooks, J., Nimphius, N., Tweed, W. A., Lee, T. L., Tweed, W. A., Phua, W. T., Chong, K. Y., Lim, E., Finegan, B. A., Coulson, C., Lopaschuk, G. D., Clanachan, A. S., Fournier L., Cloutier R., Major D., Sharpe, M. D., Wexler, H. R., Dhamee, M. Saeed, Rooney, R., Ong, S. K., O’Leary, E., McCarroll, M., Phelan, D., Young, T., Coghlan, D., O’Leary, E., Blunnie, W. P., Splinter, W. M., Splinter, W. M., Ryan T., Maguire M., Bouchier-Hayes D., Cunningham A. J., Kamath, M. V., Fallen, E. L., Murkin, J. M., Shannon, N. A., Montgomery, C. J., Karl, H. W., Raymond, Jacques, Drolet, Pierre, Tanguay, M., Blaise, G., Garceau, D., Dumont, L., Omri, A., Sharkawi, M., Billard, V., Bourgain, J. L., Panos, A., Mazer, C. D., Lichtenstein, S. V., Bevan, J. C., Popovic, V., Baxter, M. R. N., Donati, F., Bevan, D. R., Bachman, C., Kopelow, M., Donen, N., Umôn, D. T., Kemp, S., Hartley, E., Sikich, N., Roy, W. L., Lerman, J., Cooper, Richard M., Yentis, S. M., Bissonnette, B., Halpern, L., Roy, L., Burrows, F. A., Fear, D. W., Hillier, S., Sloan, M., Crawford, M., Blssonnette, B., Sikich, N., Friedlander, M., Sandier, A. N., Panos, L., Winton, T., Benureof, J., Karski J., Teasdale S., Cruise C., Skala R., Zulys V., Ong, D., Chow, F., Packota, G., Yip, R., Bradley, J., Arellano, R., Sussman, G., Sosis, M., Braverman, B., Sosis, M., Ivankovich, A. D., Manganas, M., Lephay, A., Fournier, Th., Kadri, N., Ossart, M., Sandier, A. N., Turner, K. E., Wick, V., Wherrett, C., Sullivan, P. J., Dyck, J. B., Varvel, J., Shafer, S. L., Fiset, P., Balendran, P., Meistelman, C., Lira, E., Sloan, M., Nigrovic, V., Banoub, M., Splinter, W. M., Roberts, D. W., Rhine, E. J., MacNeill, H. B., Bonn, G. E., Clarke, W. M., Noel, L. P., Ryan T., Moriarty J., Bouchier-Hayes D., Cunningham A. J., Sandier, A. N., Baxter, A. D., Norman, P., Samson, B., Hull, K., Chung, F., Mali, N., Evans, D., Cruise, C., Shumka, D., Seyone, C., Leung, Peter T., Badner, N. H., Komar, W. E., Rajasingham, M., Farren, B., Vaillancourt, G., Cournoyer, S., Hollmann, C., Breen, T. W., Janzen, J. A., Crochetiere, C. T., McMorland, G. H., Douglas, M. J., Kamani, A. A., Arora, Sunil K., Tunstall, M., Ross, J., Mayer, D. C., Weeks, S. K., Norman, P., Daley, D., Sandier, A., Guay, J., Gaudreault, P., Boulanger, A., Tang, A., Lortie, L., Dupuis, C., Backman, S. B., Bachoo, M., Polosa, C., Moudgil, G. C., Frame, B., Blajchman, H. A., Singal, D. P., Albert, J. -F., Ratcliff, A., Law, J. -C., Varvel, J., Hung, O., Shafer, S. L., Fiset, P., Balendran, P., Burgess, P. M., Doak, G. J., Duke, P. C., Sloan, P. A., Mather, L. E., McLean, C. F., Rutten, A. J., Nation, R. L., Milne, R. W., Runciman, W. B., Somoggi, A. A., Haack, Carol, Shafer, Steven L., Irish, Craig L., Weisleider, Louis, Mazer, C. David, Bell, Robert S., Dejonckheere, M., Levarlet, M., d’Hollander, A., Taylor, R. H., Sikich, N., Campbell, F., McLeod, M. E., Swartz, J., Spahr-Schopfer, I., McIntyre, B. G., Roy, W. L., Laycock, G. J. A., Mitchell, I. M., Morton, N. S., Logan, R. W., Campbell, F., Yentis, S. M., Fear, D., Halpem, L., Sloan, M., Badgwell, J. Michael, Kleinman, Sam, Yentis, S. M., Britton, J. T., Hannallah, R. S., Schafer, P. O., Norden, J. M., Splinter, W. M., Menard, E. A., Derdamezi, J. B., Ghurch, J. G., Britt, B. A., Radde, I. C., Sosis, M., Kao, Y. James, Norton, Richard G., Volgyesi, G. A., Spahr-Schopfer, I., Sosis, M., Plum, Mark, Sosis, M., Smith, C. E., Pinchak, A. C., Hancock, D. E., Owen, P., McMeekin, J., Hanson, S., Cujec, B., Feindel, C. M., Cruz, J., Boylen, P., Ong, D., Murphy, J. T., Dupuis, J. Y., Nathan, H. J., Cattran, C., Wynands, J. E., Murphy, J. T., Kinley, C. E., Sulliyan, J. A., Landymore, R. W., Robblee, James A., Labow, Rosalind, Buckley, D. N., Sharpe, M. D., Guiraudon, G., Klein, G., Yee, R., Black, J., Devitt, J. H., McLellan, B. A., Dubbin, J., Ehrlich, L. E., Ralley, F. E., Robbins, G. R., Symcs, J. F., Bourke, M., Nathan, H., Wynands, J. E., Maritime Heart Centre, and Maritime Heart Centre

Published
1991
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13. Erratum

Author

Michèle, Saiah, Alain, Borgeat, Oliver, Wilder-Smith, Hung, Orlando R., Hope, Charles E., Laney, Geoffrey, Whynot, Sara C., Coonan, Thomas J., Malloy, David S., Patterson, S., Gelb, A., Manninen, P., Strum, D., Glosten, B., Spellman, M. J., Eger, E. I., Craen, R. A., Gelb, A. W., Murkin, J. M., Chong, K. Y., Penning, D. H., El-Behairy, H., Brien, J. F., Coh, J. W., Arellano, R., Correa, J., Fedorko, L., Arellano, R., Liu, Z., Boylan, J. F., Sandler, A. N., Nierenberg, H., Sheiner, P. A., Greig, P. D., O’Leary, G. M., Teasdale, S. J., Glynn, M. F. X., Orser, B. A., Wang, L. -Y., MacDonald, J. F., Loomis, C. W., Arunachalam, K. D., Vyas, D., Milne, B., Gagnon, Daniel, Lavoie, Josée, Dupuis, Jean-Yves, Miller, D. R., Martineau, R. J., Greenway, D., Olivaris, L., Hull, K., Tierney, R. N. M., Wynands, J. E., Martineau, R., St-Jean, B., Kitts, J., Miller, D., Lindsay, P., Curran, M., Allen, G. C., Crossan, M. L., Wise, Richard, Donati, François, Bevan, David R., Hardy, J. F., Desroches, J., Perrault, J., Carrier, M., Robitaille, D., Ansley, D. M., O’Connor, J. P., Dolman, J., Townsend, G. E., Ricci, D., Liepert, D. J., Browne, P. M., Hertz, T., Rooney, M., Yip, R. W., Code, W., Phillips, A. A., McLean, R. F., Devitt, J. H., Harrington, E. M., Byrick, R. J., Wong, P. Y., Wigglesworth, D., Kay, J. C., Sinclair, L. A., Koch, J. P., Deemar, K. A., Christakis, G. K., Belo, S., Angle, P., Cheng, D., Boylan, J., Sandler, A., Feindel, C., Carmichael, F., Boylen, P., Boylen, P., DeLima, L. G. R., Nathan, H. J., Hynes, M. S., Bourke, M. E., Russell, G. N., Seyone C., Chung F., Chartrand, Daniel, Roux, Lucie, Dain, S. L., Smith, B. D., Webster, A. C., Wigglesworth, D. F., Rose, D. K., Caskennette, G., Mechetuk, C., Doyle, D. John, DeMajo, Wilfred, van den Bosch, Frank, Lee, Mark, McClenaghan, K. M., Mazer, C. D., Preston, R., Crosby, E. T., Kotarba, D., Dudas, H., Elliott, R. D., Enns, J., Manninen, P. H., Farrar, J. K., Huzyka, David L., Lin, L. Philip, Fossey, Susan, Finucane, Brendan T., Stockwell, M., Lozanoff, S., Lang, S., Hyssen, J., Campbell, D. C., Douglas, M. J., Pavy, T. J. G., Flanagan, M. L., McMorland, G. H., Bands, Colin, Ffaracs, Ch. B., Lipsett, Catherine, Drover, David, Stafford-Smith, Mark, Stevens, Sarah, Shields, Kate, MacSween, Michael J., McAllister, J. D., Morley-Forster, P. K., White, A. K., Taylor, M. D., Vandenberghe, H. M., Knoppert, D., Reimer, H., Duke, P. C., Kehler, C. H., Kepron, M. W., Taraska, V. A., Carstoniu, J., Norman, P., Katz, J., Hannallah, Medhat, Cooney, C. M., Lyons, J. B., Hennigan, A., Blunnie, W. P., Moriarty, D. C., Dobkowski, W. B., Prato, F. S., Shannon, N. A., Drost, D. J., Arya, B., Wills, J. M., Bond, D., Morley-Forester, P., JB, Mullen, Spahr-Schopfer, I., Lerman, J., Cutz, E., Dolovich, M., Kowalski, S., Ong, B., Bell, D., Ostryzniuk, T., Serrette, C., Wasylak, T., Coke, S., Tsuda, Takako, Nakagawa, Takashi, Mabuchi, Norifumi, Ando, Hiroshi, Nishida, Osamu, Azami, Takafumi, Katsuya, Hirotada, Goto, Yukio, Searle, N., Roy, M., R. R. T., Smith, Charles E., Pinchak, Alfred C., Hagen, Joan F., Hancock, Donald, Krassioukov, Andrei V., Weaver, Lynne C., Sutton, I. R., Mutch, W. A. C., Teskey, J. M., Thomson, I. R., Rosenbloom, M., Thiessen, D., Teasdale S., Corbin H., Graham, M. R., Lang, S. A., Chang, P., Gerard, M., Tetzlaff, J. E., Walsh, M., Yoon, H., Warriner, Brian, Fancourt-Smith, Peter, McEwen, Jim, Crane, Judy, Badner, N. H., Bhandari, R., Komar, W. E., Ganapathy, S., Warriner, C. B., McCormack, J. P., Levine, M., Glick, N., Chan, V. W. S., McQuestion, M., Gomez, M., Cruise, C., Evana, D., Shumka, D., Smyth, R. J., Graham, M., Halpenny, David, Goresky, Gerald V., Zaretski, J. Eldon, Kavanagh, B., Roger, S., Davies, A., Friedlander, M., Cohen M. M., Duncan P. G., Pope W. D. B., Biehl D., Merchant R., Tweed, W. A., Tessler, Michael J., Angle, Mark, Kleiman, Simcha, Kavanagh, B. P., Doak, G. J., Li, G., Hall, R. I., Sulliyan, J. A., Yee, I., Halpern, S., Pittini, R., Huh, C., Bryson, G. L., Gverzdys, R., Perreault, C., Ferland, L., Gobeil, F., Girard, D., Smyth, R., Asokumar, B., Glynn, M., Silveira, Sandra, Clark, Jeff, Milgram, Paul, Splinter, W. M., MacNeill, H. B., Ménard, E. A., Rhine, E. J., Roberts, D. J., Gould, G. M., Johnson, G. G., Quance, Daniel, Wiesel, Saul, Easdown, Jane, Truong, N. Tien, Miller, Normand, Sheiner, Nathan, Welborn, L., Norden, J., Hannallah, R., Broadman, L., Seiden, N., Iwai, M., Iwai, R., Horigome, H., Yamashita, M., Wood, Catherine E., Klassen, Kim, Kleinman, S., Yentis, S., Sikich, N., Yemen, T. A., Mascik, B., Nelson, W., Ghantous, H., Gandolfi, J., Wood, Gordon, Ali, Mohamed, Inman, Kevin, Karski, J. M., Carroll, J., Brooks, D., Oakley, P. A., Webster, P. M., Karski, J., Yao, T., Ivanov, J., Young, P., Carson, S., Weisel, R. D., Cooper, Richard M., Wong, David T., Wagner, Douglas P., Knaus, William A., Munshi, Charul A., Kampine, John P., Soutter, I. D., Mathieu, A., Gafni, A., Dauphin, A., Torsher, L., Tierney, M., Hopkins, H. S., Baylon, G. J., Peter, Elizabeth A., Bellhouse, C. P., Dore, Caroline, Rachwal, T. W., Lanigan, D. T., Yip, Raymond, Derdemezi, J. B., Britt, B. A., Withington, D. E., Reynolds, F., Patrick, A., Man, W., Searle, N. R., Ste-Marie, H., Kostash, Mark A., Johnston, Richard, Bailey, R. J., Sharpe, M. D., Woda, R. P., Haug, M., Slugg, P., Lockrem, J., Barnett, G., Finegan, B. A., Robertson, M., Taylor, D., Frost, G., Koshal, A., Rodney, Grant E., Reichert, Clayton C., O’Regan, Desmond N., Blackstock, Derek, Steward, David J., Wenstone, Richard, Harrington, Ellen, Wong, A., Braude, B., Fear, D., Bissonnette, B., Reid, Craig W., Hull, Kathryn A., Yogendran, S., McGuire, G., Chan, V., Hartley, E., Van Kessel, K., Weisel, R., Takla, N., Tremblay, N. A., Ralley, F. E., Ramsay, J. G., Robbins, G. R., Salevsky, F. C., Gandhi, S., Nimphius, N., Dionne, Bernard, Jodoin, Christian, Lorange, Michel, Lapointe, Alain, Hawboldt, Geoffrey, Volgyesi, G. A., Tousignant, Guy, Barnett, R., and Gallant, B.

Published
1992
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14. Abstracts

Author

O’Callaghan, J. P., Williams, R. T., Cruise, C. J. E., Crago, R. R., Paluck, S. M., Carmichael, F. J., Shulman, D., Volgyesi, G., Brown, K., Lerman, J., England, S., Bryan, A. C., Wexler, H. R., Pikul, J., Thomas, T. C., Zornow, M. H., Scheller, M. S., Unger, R. J., Sosis, M., Heller, S., Maltby, J. R., Koehli, N., Ewen, A., Schaffer, E. A., Cramb, R. J., Fargas-Babjak, A., Diamond, M. J., Bailey, D., McPhee, A., Loper, K., Dorman, B., Ready, L. B., Hutchinson, A., Collman, P. I., Seal, R. F., Manning, G. T., Growe, G. H., Jenkins, L. C., Nathan, H. J., Harrison, M., Dubé, L., Sweet, J., Foster, C., Bourke, M., Cattran, C., Salle, G. de la, Robblee, J., Schwieger, I. M., Gallagher, C. J., Finlayson, D. C., Bryan, J. A., Daley, W., Skrobik, Y., Webster, R., Marquez-Julio, A., David, T., Cruise, C., Blaise, G. A., Lenis, S. G., Girard, D., Hollmann, C., Meloche, R., Ralley, F. E., Ramsay, J. R., Wynands, J. E., O’Connor, J. P., Bilodeau, J., O’Leary, G., Bimbaum, P., Weisel, R. D., Mullen, J. C., Young, P., Madonik, M., Ivanov, J., Teasdale, S. J., Burrows, F. A., Williams, W. G., Teoh, K. H., Edmonds, J., Belo, S., Mazer, C. D., Lim, G., Skinner, M. I., Rose, E. A., Knill, R. L., DeJesus, J. M., Robbins, G. R., Crosby, E. T., Miller, D. R., Hamilton, P. P., Badner, N. H., Nielson, W. R., Munk, S., Gelb, A. W., Smith, H., Yu, P. Y. H., Gambling, D. R., Cole, C., McMorland, G. H., Cheng, D. C. H., Chung, F., Burns, R. J., Feindel, C. M., Irish, C. X., Manninen, P. H., Wong, H., Kehler, C. H., Beattie, W. S., Fallen, E. L., Martin, R., McKenty, S., Tétrault, J. P., Russell, G. B., Snider, M. T., Loomis, J. L., Richard, R. B., Rutherford, T. M., McLeod, M. E., McEvedy, B. A. B., Kirpalani, H., Volgyesi, G. A., Vaghadia, H., Ford, R. W., Wong, D. T., Valley, R. D., Bissonnette, B., Flanagan, M. L., Fuller, J., Ross, P. L., Wolf, G. L., Simpson, J. I., McEllistrem, R., Schell, J., O’Matley, K., Cunningham, A. J., Berman, S., Rosenquist, R. W., Finucane, B. T., Bucyk, B., Carle, H. L., LeGatt, D., Finegan, B., Bigeleisen, P. E., Schisler, J. Q., Tateishi, A., Drummond, J. C., Fleischer, J. E., Shearman, G. T., Strong, H. A., Miyasaka, K., Sinclair, L., Moote, C. A., Lim, C., Code, W. E., Roth, S. H., Bland, B. H., Strunin, L., Lam, A., Nantau, W. E., Robertson, K. M., Hramiak, I. M., Elphinstone, M. G., Archer, D. P., Pappius, H. M., Bickler, P., Gregory, G. A., Severinghaus, J. W., Spintge, R., Droh, R., Chung, A., Taylor, A. E., Stone, R. M., Meier, H. M. R., Lautenschlaeger, E., Seyone, C., Devitt, J. H., McLean, R. F., Byrick, R. J., Mullen, J. B. M., Bell, R. S., Forbes, D., Kay, J. C., Swartz, J., Fear, D. W., Boylan, J. F., Carton, E., McDonald, N. J., Scarlett, W. P., Moriarty, J., Tessler, M. J., Biehl, D. R., Naughler, M. A., Liepert, D. J., Douglas, M. J., Kim, J. H. K., Ross, P. L. E., Oyston, J., Bell, S. D., Berman, R., Ensalada, L., Chan, V., Kirby, T. J., Sandler, A., Grant, R., Morgan, C., Page, M., Malm, D., Huckel, V., Jenkins, L., Salevsky, F. C., Whalley, D. G., O’Toole, D. P., Malviya, S., Benson, L., Johnston, A. E., Finegan, B. A., Clanachan, A. S., Buckley, D. N., Deguzman, C., Hewson, J. R., Forrest, J. B., Sharpe, M. D., Lam, A. M., Merchant, R., Irish, C. L., Murkin, J. M., Cleland, A., MacDonald, J. L., Mayer, R., Dobson, J. A. R., Davies, J. M., Hodgson, G. H., Tough, J., Cattran, C. B., Nolan, K., Allen, G., Erian, R. F., Donati, F., Bevan, D. R., VanDerSpek, A. F. L., Reynolds, P. I., Ashton-Miller, J. A., Stohler, C. J., Smith, C. E., Katz, J. M., Ruta, T. S., Mutch, W. A. C., Cole, D. J., Shapiro, H. M., Hagen, B. A., Labrecque, P., Tyler, J. L., Meyer, E., Casey, W. F., Trop, D., Farrar, J. K., Tweed, W. A., Meschino, A., Schwartz, M. L., Koch, J. P., Couper, J. L., Lombard, T. P., Arciszewski, S. A., Browne, R. A., Ashworth, E. J., Duke, P. C., Sitar, D. S., Benthuysen, J. L., Smith, N. T., Hall, R. I., Hug, C. C., Hudson, R. J., Bergstrom, R., Thomson, I. R., Sabourin, M. A., Rosenbloom, M. R., Chapman, K. R., Romanelli, J., Leenen, F. H. H., Broadman, L. M., Rice, L. J., Hannallah, R. S., Forbes, R. B., Croskey, K. L., Dull, D. L., Murray, D. J., Dillman, J. B., Murphy, K., Kaplan, R. F., Welborn, L. G., Fink, R., Sandhar, B. K., Goresky, G. V., Shaffer, E. A., Roy, W. L., Christensen, S. K., Farrow-Gillespie, A. C., Plante, J. M., Denault, P., Sloan, I. A., Koren, G., O’Callaghan, A. C., Goodman, A., Godfrey, S., Pudimat, M. A., Chong, C., Andrien, H. K., and Rose, D. K.

Published
1988
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15. Abstracts

Author

Bertram, S. G., Koch, J. P., Dubbin, J. D., Maggisano, R., McKenzie, R. N., Thomson, I. R., Hudson, R. J., Torchia, M., Rosenbloom, M., Wynands, J. E., Ansley, D. M., Bent, J. M., Ramsay, J. G., Whalley, D. G., Ralley, F. E., Carli, F., Smedstad, K. G., Morison, D. H., McCanoll, S. M., Cartwright, P., Weeks, S. K., Donati, F., Michoud, M. C., Amyot, R., Jeanneret-Grosjean, A., Couture, J., McDonald, N. J., Lavelle, P., Harpin, R. P., Gallacher, W. N., Baker, J. P., Kitts, J. B., Veilleux, L. J., McBurney, R., Martineau, R., Bissonnette, B., Lerman, J., Lim, G., Chung, D. C., Plourde, G., Hardy, J. F., Bany, P. P., Tardif, L., Labrecque, P., Archer, D. P., Tyler, J., Meyer, E., Trop, D., Brown, S. C., Lam, A. M., Manninen, P. H., Katz, J. M., Abou-Madi, M., Abou-Madi, N., Woodcock, T. E., Murkin, J. M., Farrar, J. K., Tweed, W. A., Guiraudon, G., McKenzie, F. N., Nadeau, S. G., Robblee, J. R., Mensink, F. J., Kozody, R., Kehler, C. H., Wade, J. G., Bevan, D. R., Baxter, M., Bevan, J. C., McCarroll, S. M., Antzaka, C., McCready, D., Lahoud, J., O’Brien, D. J., Moriarty, D. C., Hope, C. E., Liberman, B. A., Skala, R., Lam, A., Gelb, A., Gelb, A. W., Steinberg, G. K., Neto, A. Rassi, Bellefleur, M., Layon, J., Gallagher, T. J., Berman, L. S., Davidson, D. D., Duke, P. C., Parrott, J., Palahniuk, R. J., Cunningham, A. J., Casey, W., Hannon, V., Litak, C., Ansley, D., Fullerton, H., Ripley, A. R., Sami, M. H., Harrison, L., Robbins, G. R., Fullerton, H. A., Nathan, H. J., Arvieux, C. C., Foëx, P., Ryder, W. A., Jones, L. A., Moffitt, E. A., Mclntyre, A. J., Imrie, D. D., Kinley, C. E., Sullivan, J. A., Murphy, D. A., Cannon, J. E., Morris, A., Robbins, R., Ramsay, J. R., Blaise, G., Sill, J. C., Nugent, M., Vanhoutte, P. M., Moote, C. A., Skinner, M. I., Grace, D. M., Knill, R. L., Johnston, R. G., Anderson, B. J., Noseworthy, T. W., Shustack, A., Forbes, R. B., Kumar, V., Mitros, F. A., Johnson, G. M., Coleman, P., Roth, S., Macnab, M. S. P., Gelb, A. W., Fuller, J., Karlik, S., Diamond, C., Hannallah, R. S., Patel, R. I., Ehrenpreis, M. B., Soliman, I. E., Cunliffe, M., Britt, B. A., Kapsten, J. E., Broadman, L. M., Norrie, W. C., Mundy, G. L., Belman, A. B., Anderson, K. D., Guzetta, P. C., Sharpe, T. D., Goresky, G. V., Sabourin, M. A., Ahuja, B., Eustis, S., Smith, D., Lenis, S., Archer, D., Ravussin, P., Bélisle, S., Saint-Germain, J. F., Chung, F., Meier, R., Lebrun, M., Dubé, S., Côté, C., Byrick, R. J., Howie, G., Kay, J. C., Waddell, J. P., and Mullen, B.

Published
1986
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16. Abstracts

Author

Crosby, E. T., Halpern, S., Bill, K. M., Flynnn, R. J., Moore, J., Navaneelan, C., Cunningham, A., Yu, P. Y. H., Gamling, D. R., McMorland, G. H., Perreault, C., Guay, J., Gaudreault, P., Hollman, C., Meloche, R., Hackman, T., Sheps, S. B., Murray, W. B., Heiman, P. A., Slinger, P., Triolet, W., Jain, U., Rao, T. L. K., Dasari, M., Pifarre, R., Sullivan, H., Calandra, D., Friesen, R. M., Bjornson, J., Hatton, G., Parlow, J. L., Casey, W. F., Broadman, L. M., Rice, L. J., Dailey, M., Andrews, W. R., Stigi, S., Jendrek, V., Shevde, K., Withington, D. E., Saoud, A. Tazi, Ramsay, J. G., Bilodeau, J., Johnson, D., Mayers, I., Doran, R. J., Wong, P. Y., Mullen, Brendan J., Wigglesworth, D., Byrick, R. J., Kay, J. Colin, Stubbing, J. F., Sweeney, B. P., Dagher, E., Dumont, L., Lagace, G., Chartrand, C., Badner, N. H., Sandier, A. N., Leitch, L., Koren, G., Erian, R. F., Bunegin, L., Shulman, D. L., Burrows, F., O’Sullivan, K., Bouchier, D., Kashin, B. A., Wynands, J. E., Villeneuve, E., Blaise, G., Guerrard, M. J., Buluran, J., Effa, E., Vaghadia, H., Jenkins, L. C., Janisse, T., Scudamore, C. H., Patel, P. M., Mutch, W. A. C., Ruta, T. S., McNeill, B. R., Murkin, J. M., Gelb, A. W., Farrar, J. K., Johnson, G. D., Adams, M. A., Lillicrap, D. P., Lindblad, T., Beattie, W. S., Buckley, D. N., Forrest, J. B., Lessard, M. R., Trépanier, C. A., Baribault, J. P., Brochu, J. G., Brousseau, C. A., Cote, J. J., Denault, P., Whang, P., Moudgil, G. C., Daly, N., Morrison, D. H., Ogilvie, R., Man, J., Ehler, T., Leitch, L. F., Dupuis, J. Y., Martin, R., Tessonnier, J. M., Barry, A. W., Milne, B., Quintin, L., Gillon, J. Y., Pujol, J. F., DeMonte, F., Zhang, C., Hamilton, J. T., Zhou, Y., Plourde, G., Picton, T. W., Kellett, A., Pilato, M. A., Bissonnette, B., Lerman, J., Brown, K. A., Dundee, J. W., Sosis, M., Dillon, F., Stetson, J. B., Voorhees, W. D., Bourland, J. D., Geddes, L. A., Shoenlein, W. E., O’Leary, G., Teasdale, S., Knill, R. L., Rose, E. A., Berko, S. L., Smith, C. E., Sadler, J. M., Bevan, J. C., Donati, F., Bevan, D. R., Tellez, J., Turner, D., Kao, Y. J., Salidivia, V., Roldan, L., Orrego, H., Carmicheal, F. J., Kent, A. P., Parker, C. J. R., Hunter, J. M., Finley, G. A., Goresky, G. V., Klassen, K., McDiarmid, C., Shaffer, E., Vaughan, M., Randolph, J., Szalados, J. E., Lazzell, V. A., Creighton, R. E., Poon, A. O., Mclntyre, B., Douglas, M. J., Swenerton, J. E., Farquharson, D. F., Landry, D., Petit, F., Riegert, D., Koch, J. P., Maggisano, R., Devitt, J. H., Jense, H. G., Dubin, S. A., Silverstein, P. I., Rodriguez, N., Wakefield, M. L., Williams, R., Dubin, S., Smith, J. J., Hofmann, V. C., Jarvis, A. P., Forbes, R. B., Murray, D. J., Dillman, J. B., Dull, D. L., Cohen, M. M., Cameron, C. B., Johnston, R. G., Konopad, E., Jivraj, K., Hunt, D., Eastley, R., Strunin, L., Fairbrass, M. J., Laganiere, S., McGilvery, M., Foster, B., Young, P., Weisel, D., Parra, L., Suarez Isla, B. A., Lopez, J. R., Hall, R. I., Hawwa, R., Kashtan, H., Edelist, G., Mallon, J., Kapala, D., Dhamee, M. Saeed, Reynolds, A. C., Olund, T., Entress, J., Kalbfleisch, J., Bell, S. D., Goldberg, M. E., Bracey, B. J., Goldhill, D. R., Bennett, M. H., Emmott, R. S., Innis, R. F., Yate, P. M., Flynn, P. J., Gill, S. S., Saunders, P. R., Geisecke, A. H., Feldman, J. M., Banner, M. J., Siriwardhana, S. A., Kawas, A., Lipton, J. L., Giesecke, A. H., Doyle, D. J., Volgyesi, G. A., Hillier, S. C., Gallagher, J., Hargaden, K., Hamil, M., Cunningham, A. J., Scott, W. A. C., Sielecka, D., Illing, L. H., Jani, K., Scarr, M., Maltby, J. R., Roy, J., McNulty, S. E., Torjman, M., Carey, C., Bracey, B., Markham, K., Durcan, J., Blackstock, D., DaSilva, C. A., Demars, P. D., Montgomery, C. J., Steward, D. J., Sessler, D. I., Laflamme, P., McDevitt, S., Kamal, G. D., Symreng, T., Tatman, D. J., Durcharme, J., Varin, F., Besner, J. G., Dyck, J. B., Chung, F., Arellano, R., Lim, G., Bailey, D. G., Bayliff, C. D., Cunningham, D. G., Ewen, A., Sheppard, S. D., Mahoney, L. T., Bacon, G. S., Rice, L. R., Newman, K., Loe, W., Toth, M., Pilato, M., Classen, K., McDiamid, C., Burrows, F. A., Irish, C. L., Casey, W., Hauser, G. J., Chan, M. M., Midgley, F. M., Holbrook, P. R., Elliott, M. E., Man, W. K., Finegan, B. A., Clanachan, A. S., Hudson, R. J., Thomson, I. R., Burgess, P. M., Rosenbloom, M., Fisher, J. M., O’Connor, J. P., Ralley, F. E., Robbins, G. R., Moote, C. A., Manninen, P. H., English, M., Farmer, C., Scott, A., White, I. W. C., Biehl, D., Donen, N., Mansfield, J., Cohen, M., Wade, J. G., Woodward, C., Ducharme, J., Gerardi, A., Mijares, A., Code, W. E., Hertz, L., Chung, A., Meier, H. M. R., Lautenschlaeger, E., Seyone, C., Wassef, M. R., Devitt, F. H., Cheng, D. C. H., Dyck, B., Chan, V. W. S., Ferrante, F. M., Arthur, G. R., Rice, L., Annallah, R. H., Etches, R. C., Loulmet, D., Lacombe, P., Hollmann, C., Tanguay, M., Blaise, G. A., Lenis, S. G., Fear, D. W., Lang, S. A., Ha, H. C., Germain, H., Neion, A., Dorian, P., Salter, D., Pollick, C., Cervenko, F., Parlow, J., Pym, J., Nakatsu, K., Elliott, D., Miller, D. R., Martineau, R. J., Ewing, D., Martineau, R. J., Knox, J. W. D., Oxorn, D. C., O’Connor, J. P., Whalley, D. G., Rogers, K. H., Kay, J. C., Mazer, C. D., Belo, S. E., Hew-Wing, P., Hew, E., Tessonier, J. M., Thibault, G., Testaert, E., Chartrand, D., Cusson, J. R., Kuchel, O., Larochelle, P., and Couture, J.

Published
1989
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17. Abstracts

Author

Nicholas, J. F., Fuller, J., Frewen, T. C., Lee, R., Broadman, L. M., Soliman, I. E., Hannallah, R. S., McGill, W. A., Tsuneto, S., Yamashita, M., Miyamoto, Y., Badgwell, J. M., McLeod, M. E., Lerman, J., Creighton, R. E., O’Toole, D., McCarroll, S. M., Peyton, M., Cunningham, AJ., Ramsay, J. G., Rajagopalan, B., Harmsen, E., Bore, P., Foëx, P., Radda, G., Blaise, G. A., Lenis, S. G., Sill, C., Vanhoutte, P., Irish, C. L., Murkin, J. M., Guiraudon, G. M, Martineau, R. J., Nadeau, S. G., Montgomery, C. J., Steward, D. J., Chung, D. C., Lam, A. M., Grace, D. M., Gordon, K., Thompson, T., Donati, F., Lahoud, J., Laycock, J. R. D., Bevan, D. R., O’Connor, J. P., Ralley, RE., Katz, J. M., Sami, M. H., Wynands, J. E., Smith, CE., Bevan, D. R., Baxter, M. K., Bevan, J. C., Sangwan, S., Tang, C., Gelb, A. W., Boisvert, D. P., Marchak, E., Lunt, A., Dowman, R., Cowie, N., Kozody, R., McKay, W. P. S., Noble, W. H., Taylor, W. J., Champion, M. C., Barry, A. W., Hurtig, IB., Beland, A., Hollmann, C., Meloche, R., Ringaert, K. R. A., Mutch, W. A. C., Vaghadia, H., Schechter, M. T., Sheps, S. B., Jenkins, L. C., Allen, G. C., Cattran, C. B., Peterson, R. G., Ali, M. J., Byrick, R. J., Salerno, T. A., Baker, C. B., Lichtenstein, S. V., Sharpe, M. J., Merchant, R., Alyafi, W., Penning, D. H., Jhamandas, K., Weingarten, M., Strum, D. P., Eger II, E. I., Gallagher, T. M., Volgyesi, G. A., Miyasaka, K., Burrows, F. A., Johnson, B. H., Murphy, M. R., Szlam, F., Hug, C. C., Martin, D. C., Johnston, J. F., Levin, K. R., Silverstein, P. I., Pruett, J., Bissonnette, B., Scott, A. A., Halpem, S., Rosag, O., Swartz, J., Meeke, R. I., Knill, R. L., Rose, E. A., Soderman, R. M., Milne, B., Cervenko, F., Loomis, C., Murphy, P., Sandler, A. N., Vosu, H., Lau, L. C., Branson, R., Kearney, R. A., Rosales, J. K., Howes, W. J., Wolf, A. R., Fear, D. W., Roy, W. L., Goresky, G. V., Sharpe, T. D. E., Sabourin, MA., Polomeno, R. C., Ryan, B., Evelyn, R., Higgins, T. T., Hannal, R. S., DeSoto, M. H., Nason, S. S., Penning, J. P., Loomis, C. W., Douglas, M. J., McMorland, G. H., Gowan, J. D., Hurtig, J. B., Fraser, R. A., Whalley, D. G., Labrecque, P., Quance, D., Moote, C. A., Lok, P Y. K., Skinner, M. I., Lok, P. Y. K., Scott, W. A. C., Sielecka, D., Slinger, P. D., Lavelle, P. A., Chung, F., McDonald, N. J., McDonald, S., Maltby, J. R., Hutchinson, A., Reid, C. R. G., Whitaker, P. R., Hcin, H. A. T., Arellano, R. J., Cruise, C. J., Lokoff, P., Code, WE., Strunin, L., Manninen, P. H., Macnab, M. S. P., Lam, A., Houston, P. L., tavelle, P., Burns, R., Hall, R. I., Angert, K. C., Reeder, D. A., Moldenhauer, C. C., Teasdale, S., Ralley, F. E., Moffitt, E. A., O’Brien, D. J., Imrie, D. D., Barker, R. A., Sullivan, J. A., Kinley, CE., Block, G., Butlin, G., Sibbald, W., Cunningham, D., Sidi, A., Rush, W. R., Davis, R. F., Bergstrom, R. G., Thomson, I. R., Rosenbloom, M., Meatherall, R. C., Mensink, F. J., Maclntyre, C., Wade, J. G., Ghignone, M., Flynn, N., Cunningham, A. J., Hamilton, R. C., Beauregard, L., Martin, R., Tetrault, J. P., Johnstone, G. K., Clark, A. J. M., Houlton, P. G., Purkis, I. E., Shukla, R. C., Carmichael, F. J., Saldivia, V., Orrego, H., Moote, CA., Smith, M., Drake, H. F., Treasure, T., Olson, J., Strauss, R., Zetterstrom, H., Jonsson, L. O., Forbes, R. B., Albanese, M. A., Murray, D. J., Barcellos, W. A., Slinger, P., Triolet, W., Wilson, J., Berger, J. J., Gravenstein, J. S., McLaughlin, G., Boysen, P. G., Wolf, G. L., Simpson, J. I., Humphrey, D., and Brock-Utne, J. G.

Published
1987
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20. Technology & tools development

Author

Pefani, E., primary, Panoskaltsis, N., additional, Mantalaris, A., additional, Georgiadis, M. C., additional, Pistikopoulos, E. N., additional, Aguilar-Mahecha, A., additional, Lafleur, J., additional, Seguin, C., additional, Rosenbloom, M., additional, Przybytkowski, E., additional, Pelmus, M., additional, Diaz, Z., additional, Batist, G., additional, Basik, M., additional, Tavernier, J., additional, Brunet, L., additional, Bazot, J., additional, Chemelle, M., additional, Dalban, C., additional, Guiu, S., additional, di Martino, C., additional, Lehtio, J., additional, Branca, M., additional, Johansson, H., additional, Orre, M., additional, Granholm, V., additional, Forshed, J., additional, Perez-Bercoff, M., additional, Kall, L., additional, Nielsen, K. V., additional, Andresen, L., additional, Muller, S., additional, Matthiesen, S., additional, Schonau, A., additional, Oktriani, R., additional, Wahyono, A., additional, Haryono, S., additional, Utomo, A., additional, Aryandono, T., additional, Gagnon-Kugler, T., additional, Rousseau, C., additional, Alcindor, T., additional, Aloyz, R., additional, Assouline, S., additional, Bachvarov, D., additional, Belanger, L., additional, Camlioglu, E., additional, Cartillone, M., additional, Chabot, B., additional, Christodoulopoulos, R., additional, Courtemanche, C., additional, Constantin, A., additional, Benlimame, N., additional, Dao, I., additional, Dalfen, R., additional, Gosselin, L., additional, Habbab, F., additional, Hains, M., additional, Haliotis, T., additional, Nielsen, T. H., additional, Joncas, M., additional, Kavan, P., additional, Klink, R., additional, Langlaben, A., additional, Lebel, M., additional, Lesperance, B., additional, Mann, K., additional, Masson, J., additional, Metrakos, P., additional, McNamara, S., additional, Miller, W. H., additional, Orain, M., additional, Panasci, L., additional, Paquet, E., additional, Phillie, M., additional, Qureshi, S., additional, Rodrigue, D., additional, Salman, A., additional, Spatz, A., additional, Tetu, B., additional, Tosikyan, A., additional, Tsatoumas, M., additional, Vuong, T., additional, Ruijtenbeek, R., additional, Houtman, R., additional, de Wijn, R., additional, Boender, P., additional, Hilhorst, R., additional, Cohen, Y., additional, Onn, A., additional, Lax, A., additional, Yosepovich, A., additional, Litz, S., additional, Kalish, S., additional, Felemovicius, R., additional, Hout-Silony, G., additional, Gutman, M., additional, Shabtai, M., additional, Rosin, D., additional, Valeanu, A., additional, Winkler, E., additional, Sklair-Levy, M., additional, Kaufman, B., additional, Barshack, I., additional, Canu, V., additional, Sacconi, A., additional, Biagioni, F., additional, Mori, F., additional, di Benedetto, A., additional, Lorenzon, L., additional, di Agostino, S., additional, Cambria, A., additional, Germoni, S., additional, Grasso, G., additional, Blandino, R., additional, Panebianco, V., additional, Ziparo, V., additional, Federici, O., additional, Muti, P., additional, Strano, S., additional, Carboni, F., additional, Mottolese, M., additional, Diodoro, M. G., additional, Pescarmona, E., additional, Garofalo, A., additional, Blandino, G., additional, Ho, T., additional, Feng, L., additional, Lintula, S., additional, Orpana, K. A., additional, Stenman, J., additional, El Messaoudi, S., additional, Mouliere, F., additional, del Rio, M., additional, Guedj, A. S., additional, Gongora, C., additional, Molina, F. M., additional, Lamy, P. J., additional, Lopez-Crapez, E., additional, Rolet, F., additional, Mathonnet, M., additional, Ychou, M., additional, Pezet, D., additional, Thierry, A. R., additional, Manuarii, M., additional, Tredan, O., additional, Bachelot, T., additional, Clapisson, G., additional, Courtier, A., additional, Parmentier, G., additional, Rabeony, T., additional, Grives, A., additional, Perez, S., additional, Mouret, J. F., additional, Perol, D., additional, Chabaud, S., additional, Ray-Coquard, I., additional, Labidi-Galy, I., additional, Heudel, P., additional, Pierga, J. Y., additional, Caux, C., additional, Blay, J. Y., additional, Pasqual, N., additional, and Menetrier-Caux, C., additional

Published
2012
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21. Distinct clinical and metabolic deficits in PCA and AD are not related to amyloid distribution

Author

Rosenbloom, M. H., primary, Alkalay, A., additional, Agarwal, N., additional, Baker, S. L., additional, O'Neil, J. P., additional, Janabi, M., additional, Yen, I. V., additional, Growdon, M., additional, Jang, J., additional, Madison, C., additional, Mormino, E. C., additional, Rosen, H. J., additional, Gorno-Tempini, M. L., additional, Weiner, M. W., additional, Miller, B. L., additional, Jagust, W. J., additional, and Rabinovici, G. D., additional

Published
2011
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29. Letter

Author

Despotis, G.J., primary, Joist, J.H., additional, Hogue, C.W., additional, Alsoufiev, A., additional, Kater, K., additional, Goodnough, L.T., additional, Santoro, S.A., additional, Spitznagel, E., additional, Rosenbloom, M., additional, and Lappas, D.G., additional

Published
1996
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39. Using magnetic resonance imaging and diffusion tensor imaging to assess brain damage in alcoholics.

Author

Rosenbloom M, Sullivan EV, and Pfefferbaum A

Abstract

Brain imaging using conventional magnetic resonance imaging (MRI) has revealed that several brain structures in people with a history of chronic alcohol dependence are smaller in volume than the same brain structures in nonalcoholic control subjects. Areas that are particularly affected are the frontal lobes, which are involved in reasoning, judgment, and problem solving. Older people are especially vulnerable to the damaging effects of alcohol. It is unclear whether women show consistently more vulnerability to these changes in the brain than men do. In general, alcoholics evaluated before and after a period of abstinence show some recovery of tissue volume, whereas alcoholics evaluated again after continued drinking show further reductions in brain tissue volume. A new MR technique called diffusion tensor imaging (DTI) can aid in detecting the degradation of fibers (i.e., white matter) that carry information between brain cells (i.e., gray matter). With DTI, researchers studying alcoholics have been able to detect abnormalities in white matter not visible with conventional MRI. Ultimately DTI may be useful in elucidating the mechanisms that underlie macrostructural and functional brain changes seen with abstinence and relapse. [ABSTRACT FROM AUTHOR]

Published
2003

41. Dose-response to anaesthetic induction with sufentanil: haemodynamic and electroencephalographic effects.

Author

Sareen, J, Hudson, R J, Rosenbloom, M, and Thomson, I R

Abstract

Purpose: To determine the effect of a five-fold variation in sufentanil dose on the haemodynamic and electroencephalo graphic (EEG) response to anaesthetic induction and tracheal intubation.Methods: Thirty-four patients undergoing elective coronary artery bypass grafting (CABG) participated in this randomized double-blind study. Patients in Group L (n = 17) received 3 micrograms.kg-1 sufentanil and those in Group H (n = 17) 15 micrograms.kg-1. Premedication was 60 micrograms.kg-1 lorazepam po. Anaesthesia and neuromuscular blockade were induced by infusing sufentanil and 0.15 mg.kg-1 vecuronium i.v. over five minutes. Haemodynamic data and the electroencephalographic (EEG) spectral edge were acquired by computer and compared at Control, Induction and Intubation.Results: Sufentanil dose did not affect the haemodynamic or EEG response at end-induction. No bradyarrhythmias occurred, and the incidence of hypotension was 12% in both groups. However, during induction apparent electromyographic artifacts and a transiently greater increase in heart rate were observed in Group H. The serum sufentanil concentration at Induction was 6.1 +/- 1.8 ng.ml-1 in Group L and 25.4 +/- 8.8 ng.ml-1 in Group H, and did not correlate with haemodynamic changes. No patient recalled any intraoperative event.Conclusion: Increasing sufentanil dose from 3 to 15 micrograms-1 does not influence the ultimate haemodynamic response to induction. Combined with lorazepam premedication, 3 micrograms-1 sufentanil produces near-maximal haemodynamic and EEG effects and is adequate for induction and tracheal intubation of patients undergoing CABG. Sufentanil 15 micrograms.kg-1 is no more efficacious, and causes transient cardiovascular stimulation. [ABSTRACT FROM AUTHOR]

Published
1997

42. High-dose thiopentone for open-chamber cardiac surgery: a retrospective review.

Author

Pascoe, Edward, Hudson, Robert, Anderson, Brian, Kassum, Diamond, Shanks, Ailsa, Rosenbloom, Morley, Thomson, Ian, Pascoe, E A, Hudson, R J, Anderson, B A, Kassum, D A, Shanks, A, Rosenbloom, M, and Thomson, I R

Subjects
CEREBROVASCULAR disease prevention, CARDIOTONIC agents, CARDIOPULMONARY bypass, COMPARATIVE studies, CRITICAL care medicine, ELECTROENCEPHALOGRAPHY, CARDIAC surgery, LENGTH of stay in hospitals, INTRAVENOUS anesthesia, INTRAVENOUS anesthetics, RESEARCH methodology, MEDICAL cooperation, NARCOTICS, QUALITY assurance, RESEARCH, SAFETY, ELECTIVE surgery, SURVIVAL, TRACHEA intubation, EVALUATION research, DISEASE incidence, NEUROPROTECTIVE agents, RETROSPECTIVE studies, THIOPENTAL, THERAPEUTICS
Abstract

Copyright of Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
1996
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44. Alfentanil pharmacokinetics in patients undergoing abdominal aortic surgery.

Author

Hudson, Robert, Thomson, Ian, Burgess, Patricia, Rosenbloom, Morley, Hudson, R J, Thomson, I R, Burgess, P M, and Rosenbloom, M

Subjects
ABDOMINAL aorta surgery, FEMORAL artery, AORTIC aneurysms, AGE distribution, ALFENTANIL, BIOTRANSFORMATION (Metabolism), COMPARATIVE studies, INTRAVENOUS anesthesia, RESEARCH methodology, MEDICAL cooperation, REGRESSION analysis, RESEARCH, TIME, EVALUATION research, SURGERY
Abstract

Copyright of Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
1991
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45. A randomized double-blind comparison of fentanyl and sufentanil anaesthesia for coronary artery surgery.

Author

Thomson, I R, Hudson, R J, Rosenbloom, M, and Meatherall, R C

Abstract

Using a randomized double-blind protocol the authors compared two narcotic anaesthetic regimens in 33 patients with good ventricular function undergoing coronary artery surgery. After premedication with morphine and scopolamine, patients received either fentanyl 100 micrograms X kg-1 (n = 16), or sufentanil 15 micrograms X kg-1 (n = 17), intravenously (IV) over 10 min to induce anaesthesia. Metocurine 0.42 mg X kg-1 provided muscle relaxation. No further IV anaesthetic agents were given. The haemodynamic response to induction, intubation, and surgery, differed minimally between agents. The degree of rigidity on induction was identical with both agents, as were the intervals following induction at which patients lost consciousness, regained consciousness, or met criteria for extubation. However, the interval until extubation criteria were met did correlate with the duration of cardiopulmonary bypass. Sufentanil 15 micrograms X kg-1, was clinically indistinguishable from fentanyl 100 micrograms X kg-1, when used as the primary anaesthetic agent for coronary surgery. [ABSTRACT FROM AUTHOR]

Published
1987
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50. Reexploration for bleeding is a risk factor for adverse outcomes after cardiac operations

Author

Moulton, M.J., Creswell, L.L., Mackey, M.E., Cox, J.L., and Rosenbloom, M.

Abstract

Objective: Although previous studies have included early reexploration for bleeding as a risk factor in analyzing adverse outcomes after cardiac operations, reexploration for bleeding has not been systematically examined as a multivariate risk factor for increased morbidity and mortality after cardiac surgery. Furthermore, multivariate predictors of the need for reexploration have not been identified. Accordingly, we performed a retrospective analysis of 6100 patients requiring cardiopulmonary bypass from January 1, 1986, to December 31, 1993. Methods: Eighty-five patients who had ventricular assist devices were excluded from further analysis because of the prevalence of bleeding and the significant morbidity and mortality associated with placement of a ventricular assist device, unrelated to reexploration. In the remaining 6015 patients, potential adverse outcomes analyzed included operative mortality, mediastinitis, stroke, renal failure, adult respiratory distress syndrome, prolonged mechanical ventilation, sepsis, atrial arrhythmias, and ventricular arrhythmias. To control for the confounding effects of other risk factors, we performed a multivariate logistic regression analysis. Potential covariates considered in the logistic model included age, sex, race, history of reoperation, urgency of the operation, congestive heart failure, prior myocardial infarction, renal failure, diabetes, hypertension, chronic obstructive pulmonary disease or stroke, and the bypass and crossclamp time. Results: The overall incidence of reexploration was 4.2% (253/6015). Four independent risk factors-increased patient age (p < 0.001), preoperative renal insufficiency (p = 0.02), operation other than coronary bypass (p < 0.001), and prolonged bypass time (p = 0.03)-were identified as predictors of the need for reexploration. The preoperative use of aspirin, heparin, or thrombolytic agents and the bleeding time were not identified as predictors. Reexploration for bleeding was identified as a strong independent risk factor for operative mortality (p = 0.005), renal failure (p < 0.0001), prolonged mechanical ventilation (p < 0.0001), adult respiratory distress syndrome (p = 0.03), sepsis (p< 0.0001), and atrial arrhythmias (p = 0.006). Conclusion: These data indicate that meticulous attention to surgical hemostasis and possibly application of recently developed modalities designed to facilitate perioperative correction of coagulopathy could improve outcomes after cardiac operations. (J THORAC CARDIOVASC SURG 1996;111:1037-46)

Published
1996
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