1,133 results on '"Roques, Bernard P."'
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2. Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects
3. Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain
4. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins
5. Brain Renin-Angiotensin System Blockade by Systemically Active Aminopeptidase A Inhibitors: A Potential Treatment of Salt-Dependent Hypertension
6. Aminopeptidase A Inhibitors as Potential Central Antihypertensive Agents
7. Synergistic combinations of the dual enkephalinase inhibitor PL265 given orally with various analgesic compounds acting on different targets, in a murine model of cancer-induced bone pain
8. Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB$_1$ Receptor Knockout Mice
9. Aminophosphinic Inhibitors as Transition State Analogues of Enkephalin-Degrading Enzymes: A Class of Central Analgesics
10. Identification of Metabolic Pathways of Brain Angiotensin II and III Using Specific Aminopeptidase Inhibitors: Predominant Role of Angiotensin III in the Control of Vasopressin Release
11. Preventive and alleviative effects of the dual enkephalinase inhibitor (Denki) PL265 in a murine model of neuropathic pain
12. Modulation of disulfide dual ENKephalinase inhibitors (DENKIs) activity by a transient N-protection for pain alleviation by oral route
13. Progress in Rapid Screening of Bacillus anthracis Lethal Factor Activity
14. A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity
15. Comparison of Fluorigenic Peptide Substrates PL50, SNAPtide, and BoTest A/E for BoNT/A Detection and Quantification: Exosite Binding Confers High-Assay Sensitivity
16. Inhibitors of Enkephalin Catabolism : New Therapeutic Tool in Opioid Dependence
17. Reduction of Morphine Abstinence in Mice with a Mutation in the Gene Encoding CREB
18. New Selective Aminopeptidase N Inhibitors as Potential Therapeutics
19. Obligatory Metabolism of Angiotensin II to Angiotensin III for Zona Glomerulosa Cell–Mediated Relaxations of Bovine Adrenal Cortical Arteries
20. Pluripotentialities of a quenched fluorescent peptide substrate library: enzymatic detection, characterization, and isoenzymes differentiation
21. Opioid and CCK Systems in Anxiety and Reward
22. Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins
23. Randomised, Double-Blind, Placebo-Controlled, Dose-Escalating Phase I Study of QGC001, a Centrally Acting Aminopeptidase A Inhibitor Prodrug
24. Identification of an Endothelin-converting Enzyme-2-specific Fluorigenic Substrate and Development of an in Vitro and ex Vivo Enzymatic Assay
25. The pro-nociceptive effects of remifentanil or surgical injury in mice are associated with a decrease in delta-opioid receptor mRNA levels: Prevention of the nociceptive response by on-site delivery of enkephalins
26. Autoradiographic Comparison of the Distribution of the Neutral Endopeptidase ``Enkephalinase'' and of μ and δ Opioid Receptors in Rat Brain
27. Highly Selective Photoaffinity Labeling of μ and δ Opioid Receptors
28. The Noncovalent Complex between DNA and the Bifunctional Intercalator Ditercalinium is a Substrate for the UvrABC Endonuclease of Escherichia coli
29. Geometry of the Antitumor Drug Ditercalinium Bisintercalated into d(CpGpCpG) 2 by 1 H NMR
30. Cyclic Cholecystokinin Analogues with High Selectivity for Central Receptors
31. Complete Differentiation between Enkephalinase and Angiotensin-Converting Enzyme Inhibition by Retro-Thiorphan
32. Structure and tRNAPhe-Binding Properties of the Zinc Finger Motifs of HIV-1 Nucleocapsid Protein
33. Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain
34. Apparent Defects in Processive DNA Synthesis, Strand Transfer, and Primer Elongation of Met-184 Mutants of HIV-1 Reverse Transcriptase Derive Solely from a dNTP Utilization Defect
35. Proximity and Branch Migration Mechanisms in HIV-1 Minus Strand Strong Stop DNA Transfer
36. How the HIV-1 Nucleocapsid Protein Binds and Destabilises the (−)Primer Binding Site During Reverse Transcription
37. Inhibition of osteosarcoma-induced thermal hyperalgesia in mice by the orally active dual enkephalinase inhibitor PL37. Potentiation by gabapentin
38. Use of preproenkephalin knockout mice and selective inhibitors of enkephalinases to investigate the role of enkephalins in various behaviours
39. Mechanisms That Prevent Template Inactivation by HIV-1 Reverse Transcriptase RNase H Cleavages
40. Insights into the Multiple Roles of Pausing in HIV-1 Reverse Transcriptase-promoted Strand Transfers
41. Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus
42. Molecular Mechanism of the Zn 2+-Induced Folding of the Distal CCHC Finger Motif of the HIV-1 Nucleocapsid Protein
43. Critical implication of the (70–96) domain of human immunodeficiency virus type 1 Vpr protein in apoptosis of primary rat cortical and striatal neurons
44. Role of angiotensin III in hypertension
45. Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV‐1 envelope
46. Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-XL
47. Stimulation of HIV-1 Minus Strand Strong Stop DNA Transfer by Genomic Sequences 3′ of the Primer Binding Site
48. Conversion of brain angiotensin II to angiotensin III is critical for pressor response in rats
49. A first subnanomolar and in vivo active inhibitor of aminopeptidase A (EC 3.4.11.7)
50. The allosteric-type mechanism of tetanus toxin metalloprotease activity determines its substrate specificity
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