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218 results on '"Roperto, FRANCO PEPPINO"'

1. Sigma 2 receptor expression levels in blood and bladder from healthy and bladder cancer cattle

Author

RUSSO, VALERIA, Inglese, C, AVALLONE, LUIGI, ROPERTO, FRANCO PEPPINO, Abate, C, Zizzo, N, Munday, Js, Berardi, F, Colabufo, Na, ROPERTO, SANTE, Russo, Valeria, Inglese, C, Avallone, Luigi, Roperto, FRANCO PEPPINO, Abate, C, Zizzo, N, Munday, J, Berardi, F, Colabufo, Na, and Roperto, Sante

Abstract

The expression of sigma-2 receptor (S2R) was assayed in blood and bladder samples from healthy cattle and in blood and bladder of cattle with deltapapillomavirus-associated urothelial tumors. Samples of bladder from cattle with neoplasia had significantly higher S2R than samples of bladder from healthy cattle (95% CI 0.31-0.82, P

Published
2017

2. Papillomaviruses: a systematic review

Author

Araldi, Rodrigo Pinheiro, primary, Assaf, Suely Muro Reis, additional, Carvalho, Rodrigo Franco de, additional, Carvalho, Márcio Augusto Caldas Rocha de, additional, Souza, Jacqueline Mazzuchelli de, additional, Magnelli, Roberta Fiusa, additional, Módolo, Diego Grando, additional, Roperto, Franco Peppino, additional, Stocco, Rita de Cassia, additional, and Beçak, Willy, additional

Published
2017
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3. Autophagy and papillomavirus in urothelial bladder tumors of cattle

Author

RUSSO, VALERIA, ROPERTO, FRANCO PEPPINO, PACIELLO, ORLANDO, BORZACCHIELLO, GIUSEPPE, ROPERTO, SANTE, Urraro C., Esposito I., Riccardi M., Lucà R., Russo, Valeria, Roperto, FRANCO PEPPINO, Paciello, Orlando, Urraro, C., Borzacchiello, Giuseppe, Esposito, I., Riccardi, M., Lucà, R., and Roperto, Sante

Published
2012

6. Expression of connexin 26 in bovine skin fibropapillomas

Author

MA Da Silva, CM Medeiros do Amaral, AC de Freitas, CC Rocha Carvalho, CORTEGGIO, ANNUNZIATA, ALTAMURA, GENNARO, ROPERTO, FRANCO PEPPINO, BORZACCHIELLO, GIUSEPPE, MA Da, Silva, Corteggio, Annunziata, CM Medeiros do, Amaral, AC de, Freita, CC Rocha, Carvalho, Altamura, Gennaro, Roperto, FRANCO PEPPINO, and Borzacchiello, Giuseppe

Published
2011

8. Highlighting the life cycle of BPV:CD4+ and CD8+ lymphocytes are the main circulating targets of the BPV-2 and may represent additional sites of productive infections

Author

ROPERTO, SANTE, S. Comazzi, E. Ciusani, F. Paolini, I. Esposito, R. Lucà, V. Russo, C. Urraro, ROPERTO, FRANCO PEPPINO, A. Venuti, BORZACCHIELLO, GIUSEPPE, Roperto, Sante, S., Comazzi, E., Ciusani, F., Paolini, Borzacchiello, Giuseppe, I., Esposito, R., Lucà, V., Russo, C., Urraro, Roperto, FRANCO PEPPINO, and A., Venuti

Published
2011

10. E5 therapeutic vaccine against BPV-associated tumors and diseases

Author

R. Franconi, S. Massa, F. Paolini, A. Venuti, ROPERTO, SANTE, BORZACCHIELLO, GIUSEPPE, ROPERTO, FRANCO PEPPINO, Prof. Borzacchiello, R., Franconi, S., Massa, Roperto, Sante, F., Paolini, Borzacchiello, Giuseppe, Roperto, FRANCO PEPPINO, and A., Venuti

Abstract

Raccolta atti 1st International Workshop on Papillomavirus E5 oncogene

Published
2010

14. BPV-2 E5 in circulating blood cells of cattle with bladder tumor

Author

ROPERTO, SANTE, RUSSO, VALERIA, BORZACCHIELLO, GIUSEPPE, ROPERTO, FRANCO PEPPINO, F. Paolini, C. Raso, S. Comazzi, E. Ciusani, A. Venuti, Prof. Borzacchiello, Roperto, Sante, F., Paolini, Russo, Valeria, Borzacchiello, Giuseppe, C., Raso, S., Comazzi, E., Ciusani, Roperto, FRANCO PEPPINO, and A., Venuti

Abstract

Raccolta atti 1st International workshop on Papillomavirus E5 oncogene

Published
2010

16. AGE-RELATED CHANGES OF SKELETAL MUSCLES IN CATTLE

Author

PACIELLO, ORLANDO, TRAPANI, FRANCESCA, IOVANE, VALENTINA, ROPERTO, FRANCO PEPPINO, PAPPARELLA, SERENELLA, A. Costagliola, Paciello, Orlando, Trapani, Francesca, A., Costagliola, Iovane, Valentina, Roperto, FRANCO PEPPINO, and Papparella, Serenella

Subjects
sarcopenia, cow, skeletal muscle
Published
2009

17. Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of bovine urinary bladder

Author

ROPERTO, SANTE, PACIELLO, ORLANDO, BORZACCHIELLO, GIUSEPPE, RUSSO, VALERIA, ROPERTO, FRANCO PEPPINO, R. De Tullio, G. Cuda, M. Gaspari, C. Raso, Roperto, Sante, R., De Tullio, G., Cuda, Paciello, Orlando, M., Gaspari, Borzacchiello, Giuseppe, C., Raso, Russo, Valeria, and Roperto, FRANCO PEPPINO

Subjects
urinary bladder tumour, papillomaviru, calpain 3
Published
2009

21. OVER-ESPRESSIONE DELLA CATENA PESANTE DELLA FERRITINA NEI TUMORI DELLA VESCICA NEL BOVINO

Author

BRUN, Roberto, RUSSO, VALERIA, URRARO, chiara, ROPERTO, SANTE, PACIELLO, ORLANDO, BORZACCHIELLO, GIUSEPPE, ROPERTO, FRANCO PEPPINO, G. De Vico, Brun, Roberto, Russo, Valeria, Urraro, Chiara, Roperto, Sante, Paciello, Orlando, Borzacchiello, Giuseppe, and Roperto, FRANCO PEPPINO

Subjects
BOVINO, TUMORI DELLA VESCICA, FERRITINA
Published
2009

22. Human papillomavirus research: do we still need animal models?

Author

BORZACCHIELLO, GIUSEPPE, ROPERTO, FRANCO PEPPINO, L. Nasir, MS Campo, Borzacchiello, Giuseppe, L., Nasir, Roperto, FRANCO PEPPINO, and Ms, Campo

Abstract

Much of our understanding of Papillomaviruses's biology and pathology has derived from studies of animal papillomaviruses. Paticularly, Bovine papillomaviruses has been extensively studied contributing to the elucidation of papillomaviruses pathogenesis. In this commentary the authors argue that animal papillomaviruses still provide new avenues of research.

Published
2009

25. Expression of BAG 3 protein in the urothelial tumour in cattle

Author

RUSSO, VALERIA, ROPERTO, SANTE, TURCO, MARIA CATERINA, ROPERTO, FRANCO PEPPINO, Brun Roberto, Urraro Chiara, Rosati Alessandra, Russo, Valeria, Brun, Roberto, Roperto, Sante, Urraro, Chiara, Rosati, Alessandra, Turco, MARIA CATERINA, and Roperto, FRANCO PEPPINO

Published
2008

26. Morfopatologia tiroidea in cavalli dell’Est Europa

Author

A. Perillo, A. Tinelli, C. Losacco, G. Passantino, PACIELLO, ORLANDO, RUSSO, VALERIA, ROPERTO, FRANCO PEPPINO, A., Perillo, Paciello, Orlando, A., Tinelli, C., Losacco, G., Passantino, Russo, Valeria, and Roperto, FRANCO PEPPINO

Published
2008

27. Bovine papillomaviruses, papillomas and cancer in cattle

Author

BORZACCHIELLO, GIUSEPPE, ROPERTO, FRANCO PEPPINO, Borzacchiello, Giuseppe, and Roperto, FRANCO PEPPINO

Abstract

Bovine papillomaviruses (BPV) are DNA oncogenic viruses inducing hyperplastic benign lesions of both cutaneous and mucosal epithelia in cattle. Ten (BPV 1-10) different viral genotypes have been characterised so far. BPV 1-10 are all strictly species-specific but BPV 1/2 may also infect equids inducing fibroblastic tumours. These benign lesions generally regress but may also occasionally persist, leading to a high risk of evolving into cancer, particularly in the presence of environmental carcinogenic co-factors. Among these, bracken fern is the most extensively studied. The synergism between immunosuppressants and carcinogenic principles from bracken fern and the virus has been experimentally demonstrated for both urinary bladder and alimentary canal cancer in cows whose diets were based on this plant. BPV associated tumours have veterinary and agricultural relevance in their own right, although they have also been studied as a relevant model of Human papillomavirus (HPV). Recent insights into BPV biology have paved the way to new fields of speculation on the role of these viruses in neoplastic transformation of cells other than epithelial ones. This review will briefly summarise BPV genome organization, will describe in greater detail the functions of viral oncoproteins, the interaction between the virus and co-carcinogens in tumour development; relevant aspects of immunity and vaccines will also be discussed.

Published
2008

31. Primo caso di melanosi vescicale in un bovino

Author

C. Urraro, D'ISCHIA, MARCO, A. Napoletano, L. Panzilla, RUSSO, VALERIA, BORZACCHIELLO, GIUSEPPE, ROPERTO, SANTE, ROPERTO, FRANCO PEPPINO, C., Urraro, Russo, Valeria, Borzacchiello, Giuseppe, D'Ischia, Marco, A., Napoletano, L., Panzilla, Roperto, Sante, and Roperto, FRANCO PEPPINO

Published
2007

33. Bovine papillomavirus E5 oncoprotein binds to the activated form of the platelet-derived growth factor beta receptor in naturally occurring bovine urinary bladder tumours

Author

BORZACCHIELLO, GIUSEPPE, RUSSO, VALERIA, ROPERTO, FRANCO PEPPINO, NITSCH, LUCIO, ROPERTO, SANTE, F. GENTILE, A. VENUTI, M. S. CAMPO, Borzacchiello, Giuseppe, Russo, Valeria, F., Gentile, Roperto, FRANCO PEPPINO, A., Venuti, Nitsch, Lucio, M. S., Campo, and Roperto, Sante

Abstract

Studies regarding the functions of the bovine papillomavirus (BPV) E5 oncoprotein in vivo are lacking and no E5- mediated mechanism underlying epithelial carcinogenesis is known. We have shown that BPV-2 DNA is present in the majority of naturally occurring urinary bladder tumours of cattle and that E5 is expressed in the cancer cells. Here we show that the interaction between the platelet-derived growth factor (PDGF) b receptor and BPV E5, described in vitro in cultured cells, takes place in vivo in bovine urinary bladder cancers. In these cancers, E5 and PDGFb receptor colocalize,as shown by confocal microscopy, and physically interact, as shown by coimmunoprecipitation. Furthermore,the PDGFb receptor associated withE5 is highly phosphorylated,suggesting the functional activation of the receptor upon E5 interaction.Our results demonstrate,for the first time, that E5–PDGFb receptor interaction occurs during the natural history of bovine urinary bladder tumours, suggesting an important role for E5 in carcinogenesis. Finally, the system provides a suitable animal model of papillomavirus-associated cancer to test therapeutic vaccination against E5. Successful bladder tumour regression would provide a valuable model for therapeutic vaccination against papillomavirus-associated tumours.

Published
2006

50. Connexins as a diagnostic tool for dog breast cancer

Author

TAFURI, SIMONA, RUSSO, MARCO, RUSSO, VALERIA, A. Scibelli, DELLA MORTE, ROSSELLA, TORTORA, GENNARO, ROPERTO, FRANCO PEPPINO, LORIZIO, ROBERTO, STAIANO, NORMA, Tafuri, Simona, Russo, Marco, Russo, Valeria, A., Scibelli, DELLA MORTE, Rossella, Tortora, Gennaro, Roperto, FRANCO PEPPINO, Lorizio, Roberto, and Staiano, Norma

Published
2004

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