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355 results on '"Rondini, G."'

2. Urinary TMAO levels are associated with the taxonomic composition of the gut microbiota and with the choline TMA-lyase gene (cutC) harbored by enterobacteriaceae

Author

Dalla Via, A, Gargari, G, Taverniti, V, Rondini, G, Velardi, I, Gambaro, V, Visconti, G, De Vitis, V, Gardana, C, Ragg, E, Pinto, A, Riso, P, Guglielmetti, S, Dalla Via A., Gargari G., Taverniti V., Rondini G., Velardi I., Gambaro V., Visconti G. L., De Vitis V., Gardana C., Ragg E., Pinto A., Riso P., Guglielmetti S., Dalla Via, A, Gargari, G, Taverniti, V, Rondini, G, Velardi, I, Gambaro, V, Visconti, G, De Vitis, V, Gardana, C, Ragg, E, Pinto, A, Riso, P, Guglielmetti, S, Dalla Via A., Gargari G., Taverniti V., Rondini G., Velardi I., Gambaro V., Visconti G. L., De Vitis V., Gardana C., Ragg E., Pinto A., Riso P., and Guglielmetti S.

Abstract

Gut microbiota metabolization of dietary choline may promote atherosclerosis through trimethylamine (TMA), which is rapidly absorbed and converted in the liver to proatherogenic trimethylamine-N-oxide (TMAO). The aim of this study was to verify whether TMAO urinary levels may be associated with the fecal relative abundance of specific bacterial taxa and the bacterial choline TMA-lyase gene cutC. The analysis of sequences available in GenBank grouped the cutC gene into two main clusters, cut-Dd and cut-Kp. A quantitative real-time polymerase chain reaction (qPCR) protocol was developed to quantify cutC and was used with DNA isolated from three fecal samples collected weekly over the course of three consecutive weeks from 16 healthy adults. The same DNA was used for 16S rRNA gene profiling. Concomitantly, urine was used to quantify TMAO by ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS). All samples were positive for cutC and TMAO. Correlation analysis showed that the cut-Kp gene cluster was significantly associated with Enterobacteriaceae. Linear mixed models revealed that urinary TMAO levels may be predicted by fecal cut-Kp and by 23 operational taxonomic units (OTUs). Most of the OTUs significantly associated with TMAO were also significantly associated with cut-Kp, confirming the possible relationship between these two factors. In conclusion, this preliminary method-development study suggests the existence of a relationship between TMAO excreted in urine, specific fecal bacterial OTUs, and a cutC subgroup ascribable to the choline-TMA conversion enzymes of Enterobacteriaceae.

Published
2020

12. Neonatology

Author

Apostolidou, Ipatia, Kalpoyannis, Nikolaos, Maksimovic, D., Brajkovic, Z., Vunjak, N., Ivanovski, P., Zisovska, Elizabeta, Vragoterov, J., van Straaten, Irma, Groote, Maureen, Belopavlovic J., Pekovic-Zrnic V., Stokic A., Maĉvanin Dj., Cvejanov M., Radunovic T., Draškovic B., Komarĉevic A., Gamba P. G., Tchaprassian Z., Zanon G. F., Guglielmi M., Gancia G. P., Bruschi L., Polito E., Ferrari G., Rondini G., Zimmermann, L. J. I., van Oosten, M. C. M., Kawczyński, Paweł, Piotrowski, Andrzej, Zitek M., Pokorna P., Buriankova B., Kokstein Z., Grosek, Stefan, Kalan, Gorazd, Vidmar, Ivan, Primožič, Janez, Lazar, Iaka, Sterle, Igor, Derganc, Meta, Zupančič, Živa, Gritsan, A. I., Kolesnichenko, A. P., Torgovtseva, E. P., Kuznetsova, I. V., Bult, Y., Schreuder, A. M., and Sauer, P. J. J.

Published
1996
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13. A 2-year follow up of babies enrolled in a European multicentre trial of porcine surfactant replacement for severe neonatal respiratory distress syndrome

Author

Robertson, B., Curstedt, T., Tubman, R., Strayer, D., Berggren, P., Kok, J., Koppe, J., van Sonderen, L., Halliday, H., McClure, G., Reid, M., Bambang Oetemo, S., Okken, A., Speer, C., Schroter, W., Svenningsen, N., Walti, H., Relier, J. -P., Herin, P., Parmigiani, S., Bevilacqua, G., Volante, E., Compagnoni, G., Geurrini, P., Rondini, G., Gaioni, L., and Collaborative European Multicentre Study Group:

Published
1992
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23. The BFMNU method as an alternative to the methods in use based on energy: study of the correlation between food energy and body mass

Author

Rondini, G, Olearo, B, del Castillo, JMS, and Boselli, PM

Subjects
Body mass changes, Food mass intake, Human energy expenditure, Energy intake
Abstract

Introduction: to establish slimming guidelines and any other changing treatments is useful to know the individual's energy expenditure due to the fact that, nowadays, the incidence of many diseases related to the loss of lean mass and the accumulation of adipose tissue has increased. The dietary treatments are carried out on calculating the energy contained in food, and then put in relation to the total energy expended by the body in order to produce changes in body mass. Objective: the aim of this study was to evaluate the correlation between the food energy and body mass of different subjects in various pathophysiological conditions. Methods: one hundred and twenty subjects (male and female, aged 7-78 years old) were studied in various pathophysiological conditions and previously treated with the BFMNU (Biologic e Fisiologia Modellistica della Nutrizione Umana) method. Results: a correlation coefficient R-2 of 0.1256 was found between food energy of the diet usually followed by the subjects and their body mass. The correlation between food energy and food mass was with R-2 of 0.211. The correlation between Delta% of food energy and Delta% of body mass of the subjects, obtained through dietary treatment with the BFMNU method, was 95.77 percent. Conclusions: the correlation between food energy and body mass is not significant, being a critical point about the diets designed on an energy basis. However, the body mass of an individual is determined by mass balance, regulated by corresponding metabolic rate, calculated by the BFMNU method, thanks to which the macronutrients in the diet are absorbed, redistributed and eliminated. A significant correlation, although not straight, is demonstrated between Delta% of food energy, supplied after processing through the dietary BFMNU method, and the Delta% of body mass, obtained following the dietetic path.

Published
2018

26. The Quality of Life of Children and Adolescents with X-Linked Agammaglobulinemia

Author

Soresina A., Nacinovich R., Bomba M., Cassani M., Molinaro A., Sciotto A., Martino S., Cardinale F., De Mattia D., Putti C., Dellepiane R.M., Felici L., Parrinello G., Neri F., Plebani A., Pierani P., DeMattia D., Martire B., Armenio L., Dammacco F., Ranieri G., Masi M., Miniaci A., Pession A., Rondelli R., Notarangelo L. D., Cao, Cossu F., Del Giacco S., Manconi P., Evangelista I., Magro S., Morgione S., STRISCIUGLIO, PIETRO, Anastasio E., Schillirò G., Paganelli R., Sticca M., Sperlì D., Carpino L., Bernini G., Azzari C., Maggi E., Romagnani S., Matucci A., Vultaggio A., Castagnola E., Gattorno M., Presta G., Civino A., Gambaretto G., Fasoli S., Salpietro C., Pietrogrande M.C., DellePiane R.M., Panisi C., Cambiaghi G., Pietrogrande M., Roncarolo M.G., Aiuti A., Masera G., Biondi A., Sala A., PIGNATA, CLAUDIO, Poggi V., Menna G., Di Nardo R., D'Apuzzo A., Pelliccia A., Correra A., Marone G., SPADARO, GIUSEPPE, Carli M., Zanesco L., Basso G., Putti M.C., Semenzato G., Agostini C., Amato G.M., Aricò M., Trizzino A., Izzi G., Bertolini P., Locatelli F., Zecca M., Rondini G., Marseglia G.L., Maccario R., Bossi G., Favre C., Consolini R., Vecchi V., Sacchini P., Rinaldi G., Ugazio A.G., Rossi P., Livadiotti S., Cancrini C., Finocchi A., Stabile A., Duse M., Iacobini M., Quinti I., Moschese V., Cecere F., Morgese G., Acquaviva A., De Zan G., Strafella S., Tamaro P., Rabusin M., Tovo P.A., Nespoli L., Marinoni M., Porcellini A., Cazzola G.A., Annarosa, Soresina, Renata, Nacinovich, Monica, Bomba, Morena, Cassani, Molinaro, Anna, Antonella, Sciotto, Silvana, Martino, Fabio, Cardinale, Domenico, Mattia, Caterina, Putti, Rosa Maria, Dellepiane, Leonardo, Felici, Giovanni, Parrinello, Francesca, Neri, Alessandro, Plebani, Soresina, A, Nacinovich, R, Bomba, M, Cassani, M, Molinaro, A, Sciotto, A, Martino, S, Cardinale, F, De Mattia, D, Putti, C, Dellepiane, R, Felici, L, Parrinello, G, Neri, F, Plebani, A, Soresina, A., Nacinovich, R., Bomba, M., Cassani, M., Molinaro, A., Sciotto, A., Martino, S., Cardinale, F., De Mattia, D., Putti, C., Dellepiane, R. M., Felici, L., Parrinello, G., Neri, F., Plebani, A., Pierani, P., Demattia, D., Martire, B., Armenio, L., Dammacco, F., Ranieri, G., Masi, M., Miniaci, A., Pession, A., Rondelli, R., Notarangelo, L. D., Cao, Cossu, F., Del Giacco, S., Manconi, P., Evangelista, I., Magro, S., Morgione, S., Strisciuglio, Pietro, Anastasio, E., Schillirò, G., Paganelli, R., Sticca, M., Sperlì, D., Carpino, L., Bernini, G., Azzari, C., Maggi, E., Romagnani, S., Matucci, A., Vultaggio, A., Castagnola, E., Gattorno, M., Presta, G., Civino, A., Gambaretto, G., Fasoli, S., Salpietro, C., Pietrogrande, M. C., Panisi, C., Cambiaghi, G., Pietrogrande, M., Roncarolo, M. G., Aiuti, A., Masera, G., Biondi, A., Sala, A., Pignata, Claudio, Poggi, V., Menna, G., Di Nardo, R., D'Apuzzo, A., Pelliccia, A., Correra, A., Marone, G., Spadaro, Giuseppe, Carli, M., Zanesco, L., Basso, G., Putti, M. C., Semenzato, G., Agostini, C., Amato, G. M., Aricò, M., Trizzino, A., Izzi, G., Bertolini, P., Locatelli, F., Zecca, M., Rondini, G., Marseglia, G. L., Maccario, R., Bossi, G., Favre, C., Consolini, R., Vecchi, V., Sacchini, P., Rinaldi, G., Ugazio, A. G., Rossi, P., Livadiotti, S., Cancrini, C., Finocchi, A., Stabile, A., Duse, M., Iacobini, M., Quinti, I., Moschese, V., Cecere, F., Morgese, G., Acquaviva, A., De Zan, G., Strafella, S., Tamaro, P., Rabusin, M., Tovo, P. A., Nespoli, L., Marinoni, M., Porcellini, A., and Cazzola, G. A.

Subjects
Male, Pediatrics, medicine.medical_specialty, x-linked agammaglobulinemia, Activities of daily living, Adolescent, X-linked agammaglobulinemia, Health Status, Immunology, pedsql 4.0 generic core scale, Quality of life, children, Agammaglobulinemia, Surveys and Questionnaires, Activities of Daily Living, health-related quality of life, parents, medicine, Humans, Immunology and Allergy, PedsQL 4.0 Generic Core Scale, Child, Settore MED/38 - Pediatria Generale e Specialistica, Health related quality of life, quality of live, business.industry, Immunoglobulins, Intravenous, Genetic Diseases, X-Linked, medicine.disease, Socioeconomic Factors, Child, Preschool, Mutation, Quality of Life, Female, X-linked agammaglobulinemia - children - parents - health-related quality of life - PedsQL 4.0 Generic Core Scale, business
Abstract

Introduction: The health-related quality of life in X-linked agammaglobulinemia was investigated in 25 children and adolescents patients through the Italian version of Pediatric Quality of Life Inventory 4.0 Generic Core Scale for patients aged less then 18 years, comparing child perception to that of the parents and the physician's evaluation. The data were compared with the ones of 80 healthy controls and the literature data of a group of patients with rheumatic diseases. Discussion: The agammaglobulinemia subjects perceived a lower global quality of life than the healthy subjects, but significantly higher than the rheumatic diseases controls. The clinical relevance of health-related quality of life assessment in X-linked agammaglobulinemia pediatric patients is discussed. © 2008 Springer Science+Business Media, LLC.

Published
2009

29. Do differences in delivery room intubation explain different rates of bronchopulmonary dysplasia between hospitals?

Author

Gagliardi, Luigi, Bellù, Roberto, Lista, Gianluca, Zanini, Rinaldo, Compagnoni, G., Mosca, F., Martinelli, S., Chirico, G., Santucci, S., Caccamo, M. L., Maccabruni, M., Stronati, M., Rondini, G., Agosti, M., Magni, L. A., Moro, G., Tagliabue, P., Barera, G., Merazzi, D., Cavazza, A., Brunelli, A., Battaglioli, M., Tandoi, F., Cella, D., Perotti, G. F., Pelti, M., Stucchi, I., Frisone, F., Avanzini, A., Bastrenta, P., Iacono, G., Pontiggia, F., Cotta-Ramusino, A., Strano, F., Fontana, P., Franco, M., Rossi, L., Calciolari, G., Citterio, G., Rovelli, R., Poloniato, A., Gancia, G. P., Costato, C., Germani, R., Barp, S., Crossignani, R., Siliprandi, N., Borroni, C., Ventura, M. L., Abbiati, L., Giardinetti, S., Leva, L., Fusi, M., and Bellasio, M.

Subjects
Male, Birth weight, medicine.medical_treatment, Gestational Age, Pediatrics, law.invention, Case mix index, law, Risk Factors, mental disorders, Intubation, Intratracheal, Medicine, Intubation, Birth Weight, Humans, Infant, Very Low Birth Weight, Bronchopulmonary Dysplasia, Mechanical ventilation, business.industry, Pediatrics, Perinatology and Child Health, Obstetrics and Gynecology, Delivery Rooms, Infant, Newborn, Gestational age, General Medicine, Perinatology and Child Health, medicine.disease, Respiration, Artificial, Bronchopulmonary dysplasia, Italy, Anesthesia, Ventilation (architecture), Small for gestational age, Female, business, Infant, Premature
Abstract

To investigate whether the wide variation in the frequency of bronchopulmonary dysplasia (BPD) between hospitals is due to differences in delivery room intubation rates.Data on 1260 infants of birth weight1500 g and 23-31 weeks gestational age, born in 1999-2002 and surviving to 36 weeks, were collected; 196 (15.6%) developed BPD defined as oxygen need at 36 weeks postmenstrual age. Generalised estimating equations and conditional logistic models adjusting for centre, gestational age, propensity score for intubation, and other potential confounders were used.Rates of BPD, delivery room intubation and mechanical ventilation for24 h differed significantly between hospitals. Centres with high delivery room intubation rates had higher ventilation and BPD rates. Hospitals ventilating more often also did so for a longer time. Although delivery room intubation was associated with BPD in unadjusted analyses, neither delivery room intubation nor brief (24 h) mechanical ventilation were risk factors for BPD in multivariate analyses adjusting for gestational age, case mix and other pre- and perinatal factors, indicating no causal effect or unmeasured confounding. Significant risk factors for developing BPD were low gestational age, prolonged ventilation (24 h: adjusted OR (aOR) 2.4;7 days: aOR 14.9), male sex (aOR 1.7), being small for gestational age (SGA; aOR 4.3) and late-onset sepsis (aOR 2.2). After taking into account these variables/procedures, centre differences remained significant but explained only about 5% of variance.Differences in BPD frequency between hospitals are explained by differences in procedures, chiefly mechanical ventilation, rather than by differences in initial management or case mix. Delivery room intubation and brief mechanical ventilation did not increase BPD risk.

Published
2011

30. Prevalence, exclusivity, and duration of breast-feeding in Lombardia

Author

Macchi, L., Pirola, M. E., Monaco, G., Pavan, A., Bettinelli, M. E., Zapparoli, B., Agosti, M., Bonati, M., Banderali, G., Colombo, A., Giovannini, M., Mosca, F., Narducci, M., Nino, M. L., Rondini, G., Speri, L., Riva, E., and Fortinguerra, F.

Published
2008

31. Prevalenza, esclusività e durata dell'allattamento al seno in Lombardia

Author

Macchi, L., Pirola, M. E., Monaco, G., Pavan, A., Bettinelli, M. E., Zapparoli, B., Agosti, M., Bonati, M., Banderali, G., Colombo, A., Giovannini, M., Mosca, F., Narducci, M., Nino, M. L., Rondini, G., Speri, L., Riva, E., and Fortinguerra, Filomena

Subjects
Medicine (all)
Published
2008

36. Prophylactic nasal continuous positive airways pressure in newborns of 28-31 weeks gestation: multicentre randomised controlled clinical trial

Author

Sandri, F, Ancora, G, Lanzoni, A, Tagliabue, P, Colnaghi, M, Ventura, Ml, Rinaldi, M, Mondello, I, Gancia, P, Salvioli, Gp, Orzalesi, M, Mosca, F, Brasca, E, Fedeli, T, Pelti, M, Germani, R, Costato, C, Maffei, G, Rinaldi, G, Morgando, Mp, Cambursano, P, Strano, F, Rondini, G, Santuz, P, Biban, P, Gitto, Eloisa, Cordaro, S, Cordaro, P, Barberi, Ignazio, Gargano, G, Roversi, Mf, Ferrari, F, Compagnoni, G, Lista, G, Castoldi, F, Giordano, L, Messina, F, Napolitano, M, Marra, A, Dani, C, Rubaltelli, F, Bonacci, W, Serra, G, Piccinini, G, Santini, G, Martano, C, and Fabris, C.

Subjects
Male, newborns, medicine.medical_treatment, Partial Pressure, positive airways pressure, Drug Administration Schedule, Intensive care, medicine, Clinical endpoint, Humans, Continuous positive airway pressure, Mechanical ventilation, Respiratory Distress Syndrome, Newborn, Respiratory distress, Continuous Positive Airway Pressure, business.industry, Incidence (epidemiology), Infant, Newborn, Obstetrics and Gynecology, Pulmonary Surfactants, General Medicine, respiratory system, Clinical trial, Oxygen, Anesthesia, Pediatrics, Perinatology and Child Health, Intensive Care, Neonatal, Gestation, Regression Analysis, Female, Original Article, business, Infant, Premature
Abstract

Background: The role of nasal continuous positive airways pressure (nCPAP) in the management of respiratory distress syndrome in preterm infants is not completely defined. Objective: To evaluate the benefits and risks of prophylactic nCPAP in infants of 28–31 weeks gestation. Design: Multicentre randomised controlled clinical trial. Setting: Seventeen Italian neonatal intensive care units. Patients: A total of 230 newborns of 28–31 weeks gestation, not intubated in the delivery room and without major malformations, were randomly assigned to prophylactic or rescue nCPAP. Interventions: Prophylactic nCPAP was started within 30 minutes of birth, irrespective of oxygen requirement and clinical status. Rescue nCPAP was started when FIO2 requirement was > 0.4, for more than 30 minutes, to maintain transcutaneous oxygen saturation between 93% and 96%. Exogenous surfactant was given when FIO2 requirement was > 0.4 in nCPAP in the presence of radiological signs of respiratory distress syndrome. Main outcome measures: Primary end point: need for exogenous surfactant. Secondary end points: need for mechanical ventilation and incidence of air leaks. Results: Surfactant was needed by 22.6% in the prophylaxis group and 21.7% in the rescue group. Mechanical ventilation was required by 12.2% in both the prophylaxis and rescue group. The incidence of air leaks was 2.6% in both groups. More than 80% of both groups had received prenatal steroids. Conclusions: In newborns of 28–31 weeks gestation, there is no greater benefit in giving prophylactic nCPAP than in starting nCPAP when the oxygen requirement increases to a FIO2 > 0.4.

Published
2004

38. Post-discharge nutrition of the very low-birthweight infant: Interim results of the multicentric GAMMA study

Author

Agosti, M., Vegni, C., Calciolari, G., Marini, A., Mautone, A., De Cosmo, L., Ladisa, G., Alessandroni, R., Capretti, A., Chiappe, S., Palmas, G., Polizzi, B., Angrì, F., Catalano, L., Sabatino, G., Domizio, S., Rinaldi, G., Popolo, G., Spennati, G. F., Persia, R., Zanini, R., Bellù, R., Stronati, M., Mussini, P., Ferrari, F., Ferrari, P., Paino, G., Napolitano, M., Spinella, B., Pomo, R., Rondini, G., Polito, E., Lungarotti, S., Soldani, C., Dore, A., Oggiano, R., Mussa, G. C., Farinasso, D., Agosta, G., Saia, S., Battajon, N., Macagno, F., Chiandotto, V., and Leva, L.

Subjects
Psychomotor development, Post-discharge nutrition, 80 kcal/dl formula, VLBWI, Growth, Perinatology and Child Health, Pediatrics, Perinatology and Child Health, Pediatrics
Published
2003

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