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The pleiotropic effects of Lamium species are extensively utilized for treating urinary bladder injuries and infections and addressing blood hypertension or liver toxicities. Despite widespread Lamium consumption in animals and humans, its impact on brain biochemical parameters remains unexplored. In our study, we demonstrated the regenerative effect of L. album L. in a rat model of restraint stress, commonly employed to investigate neuropsychological stress. Following extract administration, there was a reduction in stress hormones (corticosterone, adrenaline), inflammation (TNFα), and oxidative stress. These neuroregenerative effects may be attributed to Lamium's phytochemical composition, particularly its iridoids and luteolin content, which appear to mimic the action of glucagon-like peptide 1 (GLP-1). These findings suggest the potential use of L. album as a neuroregenerative adjuvant. [ABSTRACT FROM AUTHOR]

Alzheimer's disease (AD) is known as the primary and most common cause of dementia in the middle-aged and elderly population worldwide. Chemical analyses of B. pendula leaf extract (BPE), performed using spectrophotometric and chromatographic methods (LC/MS), revealed high amounts of polyphenol carboxylic acids (gallic, chlorogenic, caffeic, trans-p-coumaric, ferulic, and salicylic acids), as well as flavonoids (apigenin, luteolin, luteolin-7-O-glucoside, naringenin, hyperoside, quercetin, and quercitrin). Four groups of Wistar rats were used in this experiment (n = 7/group): control (untreated), Aβ1-42 (2 μg/rat intracerebroventricular (i.c.v.), Aβ1-42 + BPE (200 mg/Kg b.w.), and DMSO (10 μL/rat). On the first day, one dose of Aβ1-42 was intracerebroventricularly administered to animals in groups 2 and 3. Subsequently, BPE was orally administered for the next 15 days to group 3. On the 16th day, behavioral tests were performed. Biomarkers of brain oxidative stress Malondialdehyde (MDA), (Peroxidase (PRx), Catalase (CAT), and Superoxid dismutase (SOD) and inflammation (cytokines: tumor necrosis factor -α (TNF-α), Interleukin 1β (IL-1β), and cyclooxygenase-2 (COX 2)) in plasma and hippocampus homogenates were assessed. Various protein expressions (Phospho-Tau (Ser404) (pTau Ser 404), Phospho-Tau (Ser396) (pTau Ser 396), synaptophysin, and the Nuclear factor kappa B (NFkB) signaling pathway) were analyzed using Western blot and immunohistochemistry in the hippocampus. The results show that BPE diminished lipid peroxidation and neuroinflammation, modulated specific protein expression, enhanced the antioxidant capacity, and improved spontaneous alternation behavior, suggesting that it has beneficial effects in AD. [ABSTRACT FROM AUTHOR]

In the current modern and extremely competitive educational environment, the stress experienced by students has become a compelling concern. Academic stress is highly prevalent among university students and it has a significant impact on the overall physical and mental health outcomes. Thus, the primary aim of the current investigation was to examine the relationship between perceived stress, emotional regulation, and self-efficacy among university students. A sample of 153 students aged 18 to 40 (M = 21.28, SD = 3.17, 101 females) completed self-reported scales measuring perceived stress, emotional regulation (i.e. cognitive reappraisal and expressive suppression), and self-efficacy. Correlation analyses suggested that students' stress was negatively related to self-efficacy and cognitive reappraisal. Also, we found that stress was positively related to expressive suppression. Age was not significantly associated with students' stress. Hierarchical regression analysis suggested that the final regression model (i.e., gender, self-efficacy, and emotion regulation strategies) explained 34.3% of students reported stress. The best predictor of students' stress was self-efficacy. We discuss our findings considering their practical implications in tailoring interventions aimed to reduce students' perceived stress. [ABSTRACT FROM AUTHOR]

In Romania until now, are no commercial persimmon (Diospyros kaki Thunb.) orchards. But, the interest for the fruits of this species is increse. Solitary trees of Diospyros virginiana being found in parks and private gardens it have fruits are very astringent, without interest for consuummers, but they offer a very atractive wiew in lands to the starting of the winter season. In the South of Romania, during the winter, are occasional registered temperatures of -20-25°C which cane affects the varieties from Diospyros kaki. For this reason, in 2019 year, we established an experimental plot with two cultivars Rosseyanka and Jiro, to study the persimmon culture suitability in Romania. The study carried out so far, shows that the Rosseyanka cultivar, reached a high fruits yield of 11 kg/tree, in the fourth year after planting. From the point of view of fruit quality, the Jiro variety recorded a value of fruit weight of 162.2g/fruit and 85.36 mg% vitamin C fruits contents. [ABSTRACT FROM AUTHOR]

Entrepreneurial education is what supports young people to establish new businesses that bring profit, to develop new concepts or products, to develop their capacity for professional insertion, to show a strong entrepreneurial spirit in their activity, etc. The present work aims to investigate the prospects for the development of entrepreneurial education and sustainable entrepreneurship in Romania, in the context where entrepreneurship, as a didactic discipline and respectively a field of scientific research, has a fairly recent history in the Romanian universities. This is a qualitative analysis on European and Romanian public data. In order to assess the sustainability of the data, the methodological tools involving analyses are implemented. The results indicate that entrepreneurial education leads to a significant increase in the level of economic preparation of entrepreneurs through educational programs, being at the same time an indicator for evaluating the results obtained. [ABSTRACT FROM AUTHOR]

Introduction: With the emergence and global spread of coronavirus, a state of isolation has been imposed. This has led to the closure of schools and most institutions, which are forced to adopt an online program. People have resorted to various mechanisms to combat stress, some of which are not exactly good for health. Objectives: Therefore, the main purpose of this study is to identify how the pandemic affected the relationship between emotional intelligence and alcohol consumption, one of the hypotheses being that the pandemic context mediates the relationship between alcohol consumption and emotional intelligence. Methods: In other words, we investigated the relationships between fear of COVID-19, global emotional intelligence, and alcohol consumption in a sample of young people, 18-25 years old (N = 177), most of whom were female participants (58.2%). Results: Following the statistical analysis used, the results did not support the research hypothesis, thus confirming the null hypothesis. The research design being a cross-sectional type did not allow the formulation of causal conclusions. Conclusions: Although the results were not as expected, in the future it would be desirable to implement a longitudinal study to allow conclusions such as cause-effect and also to investigate in more detail some facets of the variables studied, like social anxiety, adaptability, conscientiousness and, last but not least, the impact of the media. [ABSTRACT FROM AUTHOR]

This article aims to highlight the main qualities of a leader, but also essential differences between the basic leader and manager characteristics, achieving a Sustainable Business Leadership profile which guarantees a sustainable entrepreneurship model. This study used a complex empirical research on a Romanian complex business leader based on six identified criteria (studied and assessed further to a SBL profile), analysing particular and general relevance of each, thus assuming all as essential in characterizing and promoting a SBL. Following the analysis, it has been stated that the six investigated criteria are defining and relevant to the objective assessment for the quality of a successful business leader. The research defined an improved SBL profile, applicable to any field of activity in any democratically governed country. [ABSTRACT FROM AUTHOR]

Raman microspectroscopy was tested as an alternative/complementary method for biochemical evaluation of the synaptosomes obtained from neonatal rat brain prenatally exposed to sodium valproate and treated with allicin. Spectrophotometric assays of several oxidative stress markers (catalase, superoxide dismutase, total thiols) and acetylcholine esterase activity revealed the redox balancing function and pro-cholinergic effect of the allicin as compared to the valproate effect. Raman evaluation showed no significant changes in our experimental conditions. Different concentrations and volumes of the synaptosomes vesicles must be tested for the optimal Raman examination of these purified synaptosomes. [ABSTRACT FROM AUTHOR]

Site-directed spin labeling and EPR characterization (continuous wave as well as DEER) of two blood substitute candidates is described for the first time: glutaraldehyde-polymerized bovine hemoglobin and the related hemoglobin-albumin copolymer. In vitro, with two different types of cell cultures, these spin-labeled candidates are relatively stable; however, they appear to be rapidly reduced in vivo, most likely via removal or reduction of the spin label (as opposed to removal of the blood substitute candidate from the circulatory system altogether). [ABSTRACT FROM AUTHOR]

The plant protection activity includes all the measures taken to prevent and control all pests, diseases and harmful factors that cause damage to crops. This study follows the factors and characteristics of the machines used for phytosanitary treatments. It is also presented to what extent the use of modern agricultural machinery leads to a possible reduction in the number of treatments applied in a growing season as well as reducing the quantity of phytosanitary substance administered per hectare, in order to increase the efficacy of phytosanitary control works. It is also presented to what extent the use of modern agricultural machinery leads to a possible increase in the effectiveness of phytosanitary control works. By knowing exactly the machines and sprayers, it is possible to achieve a correct planning of control measures and avoid mistakes when applying plant protection products, to protect the environment and militate for the sustainable development of agriculture. This theoretical study shows that by creating an efficient system for monitoring and using EEP 300, EEP 400, EEP 500, EEP 1500, MIL type and MET-2500 SATURN R18 DE type sprayers in plant protection, the efficiency of the applied treatments is increased. Sistems and equipment for the application of phytosanitary treatments are part of the new trends for the practice of modern agriculture, but it must be borne in mind that phytosanitary protection is a source of environmental pollution with chemicals and must be avoided. [ABSTRACT FROM AUTHOR]

The analysis of the internal evaluations regarding the assessment of the quality of the education system by the students is a tool that stimulates the improvement of the curricula. Our study aims to put into evidence the results of the interpretation of expectations - perception matrix perception, concerning the tangible elements included in the present analysis. Although in the first year of studies there are high expectations regarding the quality of the educational spaces (Q2), the provision of equipment (Q3) and the competence of the teachers (Q4), the perceptions are only satisfactory. Regarding the book offer (Q4), the situation is different. Although there were modest expectations, the perception is very good. The expectation-perceptions matrix that reflects the opinions of the 4th year students regarding the component tangible elements of the learning process highlights that at the end of the studies there is a concordance between the initial expectations and perceptions, for 50% of the considered attributes. [ABSTRACT FROM AUTHOR]

Drinking water treatment aims to avoid or minimize some risks to human health and to provide adequate water quality by removing physical, chemical and biological contaminants. However, treatment processes require increasing efforts in terms of technology, chemicals and energy inputs, which generate increased secondary environmental impacts and added water production costs. The objective of this study is to evaluate the drinking water treatment plant (DWTP) in Iasi City (Romania) by life cycle assessment (LCA) and to identify and characterize its environmental impacts. Iasi DWTP involves the following scheme: pre-oxidation (chlorine dioxide), coagulation/flocculation, sedimentation, pH correction (calcium hydroxide), rapid sand filtration, granular activated carbon filtration and disinfection (chlorine gas). LCA was performed according to the ISO 14040 standard with the support of SimaPro 8.3. software and Eco-invent 3.3 data base. Life cycle impact assessment has been performed with Recipe 1.13. Midpoint method. The life cycle inventory included the construction and operational phases. The novelty of this study was to define two additional functional units related to removing contaminants besides the traditional 1 m³ of treated water. The main contributors to impact in most categories were: the electricity consumption (25 – 95% depending on impact category) and the ferric chloride used in coagulation/flocculation (35 – 100%, depending on impact category). Life cycle impact assessment showed that the lower the pollutant concentration, the higher the specific environmental impacts will be, which prompts for further detailed analysis of water treatment plant environmental performance in at least two directions: removal of emerging contaminants (present in very low concentrations) and a more detailed analysis on the individual performance of each treatment stage. [ABSTRACT FROM AUTHOR]

The present study was developed within the Life Sciences Learning Center project implementation at USAMV Cluj-Napoca. The main objective of the research is to improve the academic and social support mechanisms for high-risk students and to increase the promotion rate after the first year of study from 80.91% to 85%, by applying remedial guidance and support programs. This objective is being materialized by accomplishing activities such as: career counselling, coaching, personal development, guidance and development of socio-emotional skills, personalized workshops, interactive courses and blended learning courses aimed at students with a high-risk of abandonment. As a result of the implementation, it has been observed the growth of the students' motivation for autonomous learning and the access of students to a quality education. [ABSTRACT FROM AUTHOR]

One of the most important competences of academic performance is students' adaptability in the university. The ability of the young student to self-regulate behaviour is the ability to manage social intelligence, interact with other academic actors, organize time and cope with stress, these are characteristics of high-level students of self-regulation. The university dropout phenomenon in USAMV Cluj-Napoca is below the average country. The development of emotional intelligence of students is the key to personal and professional success in the university, but also a positive self-image assertion, useful to find a job on the labour market. [ABSTRACT FROM AUTHOR]

24 female Wistar rats (120 ± 10 g) were divided into 4 groups: - control group (C); - Galium verum treated group (E), (25 mg extract/100 g bw); - anakinetic stressed group (S); - stress + Galium verum extract (25 mg extract/100 g bw) treated group (SE). Results revealed different reactivity of hypothalamohypophyseal- adrenal axis in the three experimental groups. The extract administration, in conditions of exposure to stress, resulted in an enhancement of NPV neurosecretory activity - associated with a possible stimulation of CRH release, a possible activation of adenohipophyseal hormones, as well as stimulation of adrenal steroid hormones. In S group, the effects of stress were opposite to those of E and SE groups. Histological results of the study proved that the administration of Galium verum vegetal extract in condition of anakinetic stress exposure induced important morphological changes at the all constitutive assembly of hypothalamo-hypophyseal-adrenal axis. These results justify the stimulation of secretory activity of the axis. [ABSTRACT FROM AUTHOR]