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1. Cardiac assessment and inflammatory markers in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV2 (PIMS-TS) treated with methylprednisolone versus intravenous immunoglobulins: 6-month follow-up outcomes of the randomised controlled Swissped RECOVERY trial

Author

Andre, Maya C., Sanchez, Carlos, Bressieux-Degueldre, Sabrina, Perez, Marie-Helene, Wütz, Daniela, Blanchard-Rohner, Geraldine, Grazioli, Serge, Schöbi, Nina, Trück, Johannes, Welzel, Tatjana, Atkinson, Andrew, Schlapbach, Luregn J., Bielicki, Julia, Koehler, Henrik, Gysi, Spyridoula, Janz, Indra, Bieri, Andreas, Donner, Birgit, Hammer, Jürg, Heininger, Ulrich, von Kalckreuth, Clemens, Kohns, Malte, Mettauer, Nicole, Meyer, Alexandra, Reppucci, Diana, Schlaeppi, Chloé, Trachsel, Daniel, Vaezipour, Nina, Woerner, Andreas, Zutter, Andreas, Vanoni, Federica, Kottanattu, Lisa, Mazzara, Calogero, Conti, Alessia Severi, Aebi, Christoph, Agyeman, Philipp, Duppenthaler, Andrea, Glöckler, Martin, Pallivathukal, Sabine, Riedel, Thomas, Zimmermann, Petra, Cudré-Cung, Hong-Phuc, Pavlovic, Mladen, Bordessoule, Alice, Martin, Anne-Laure, Polito, Angelo, Wagner, Noemie, Rohr, Marie, L'Huillier, Arnaud, Amiet, Vivianne, Ferry, Thomas, Longchamp, David, Natterer, Julia, Oppenheim, Rebecca, Hofer, Michael, Buettcher, Michael, Wechselberger, Katharina, Donas, Alex, Germann, Sara, Erni, Michaela Lütolf, Kaiser, Daniela, Scholl, Katharina Schwendener, Kuen, Hans Peter, Hrup, Katja, Stritt, Janine, Bailey, Douggl G.N., Wachinger, Tanja, Beck, Ingrid, Birkenmaier, André, Rogdo, Bjarte, Lorenz, Philip, Iglowstein, Ivo, Zöhrer, Konstanze, Flade, Martin, Prader, Seraina, Schmid, Jana Pachlopnik, Seiler, Michelle, Sauteur, Patrick Meyer, Brotschi, Barbara, Weber, Kathrin, Whittaker, Elizabeth, and Faust, Saul N.

Published
2024
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2. COVID-19 Vaccine Acceptance Among Parents of Children With Multisystem Inflammatory Syndrome in Children

Author

Blanchard-Rohner, Geraldine, Sanchez, Carlos, Andre, Maya C., Bressieux-Degueldre, Sabrina, Grazioli, Serge, Perez, Marie-Helene, Wütz, Daniela, Schöbi, Nina, Welzel, Tatjana, Atkinson, Andrew, Schlapbach, Luregn J., Bielicki, Julia A., Trück, Johannes, Koehler, Henrik, Gysi, Spyridoula, Janz, Indra, Bieri, Andreas, Donner, Birgit, Hammer, Jürg, Heininger, Ulrich, von Kalckreuth, Clemens, Kohns, Malte, Mettauer, Nicole, Meyer, Alexandra, Reppucci, Diana, Schlaeppi, Chloé, Trachsel, Daniel, Vaezipour, Nina, Woerner, Andreas, Zutter, Andreas, Vanoni, Federica, Kottanattu, Lisa, Mazzara, Calogero, Severi Conti, Alessia, Aebi, Christoph, Agyeman, Philipp, Duppenthaler, Andrea, Glöckler, Martin, Pallivathukal, Sabine, Riedel, Thomas, Zimmermann, Petra, Cudré-Cung, Hong-Phuc, Pavlovic, Mladen, Bordessoule, Alice, Martin, Anne-Laure, Polito, Angelo, Wagner, Noemie, Rohr, Marie, L’Huillier, Arnaud, Amiet, Vivianne, Ferry, Thomas, Longchamp, David, Natterer, Julia, Oppenheim, Rebecca, Hofer, Michael, Buettcher, Michael, Wechselberger, Katharina, Donas, Alex, Germann, Sara, Lütolf Erni, Michaela, Kaiser, Daniela, Schwendener Scholl, Katharina, Peter Kuen, Hans, Hrup, Katja, Stritt, Janine, Bailey, Douggl G. N., Wachinger, Tanja, Beck, Ingrid, Birkenmaier, André, Rogdo, Bjarte, Lorenz, Philip, Iglowstein, Ivo, Zöhrer, Konstanze, Flade, Martin, Prader, Seraina, Pachlopnik Schmid, Jana, Seiler, Michelle, Meyer Sauteur, Patrick, Brotschi, Barbara, Weber, Kathrin, Whittaker, Elizabeth, and Faust, Saul N.

Published
2024
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3. Community Versus Vertically Acquired Neonatal SARS-CoV-2 Infection: The EPICENTRE Cohort Study

Author

De Luca, Daniele, Perkins, Elizabeth, Tingay, David G., Buonsenso, Danilo, Centorrino, Roberta, Vivanti, Alexandre, Rooze, Shancy, Pilar-Orive, Francisco J, Gonçalves-Ferri, Walusa Assad, Amigoni, Angela, de Carvalho, Werther Brunow, Jornada Krebs, Vera Lucia, AL-Naqeeb, Niran, Danhaive, Olivier, Cetinkaya, Merih, Stein, Howard, Shoemaker, Jessica, Danhaive, Olivier, Torpiano, Paul, Vetter-Laracy, Susanne, Rogdo, Bjarte, Elsayed, Yasser, Chidini, Giovanna, Kneyber, Martin, Medina Villanueva, Alberto, Polito, Angelo, Brouwer, Carole NM, and Rimensberger, Peter

Published
2023
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4. Outcomes for Infants Born in Perinatal Centers Performing Fewer Surgical Ligations for Patent Ductus Arteriosus: A Swiss Population-Based Study

Author

Meyer, Philipp, Kusche, Rachel, Mori, Andrea Capone, Kaeppeli, Daniela, Schulzke, Sven M., Brotzmann, Marc, Ramelli, Gian Paolo, Goeggel, Barbara Simonetti, McDougall, Jane, Humpl, Tilman, Steinlin, Maja, Grunt, Sebastian, Gebauer, Mathias, Hassink, Ralph, Riedel, Thomas, Keller, Elmar, Killer, Christa, Blanchard, Gaelle, Pfister, Riccardo E., Huppi, Petra S., Borradori-Tolsa, Cristina, Tolsa, Jean-François, Roth-Kleiner, Matthias, Bickle-Graz, Myriam, Stocker, Martin, Schmitt-Mechelke, Thomas, Bauder, Florian, Erkert, Bernd, Mueller, Anita, Ecoffey, Marc, Malzacher, Andreas, Rogdo, Bjarte, Lang-Dullenkopf, Anette, Hegi, Lukas, von Rhein, Michael, Bernet, Vera, Tomaske, Maren, Bassler, Dirk, Arlettaz, Romaine, Hagmann, Cornelia, Latal, Bea, Etter, Ruth, Adams, Mark, Natalucci, Giancarlo, Schneider, Juliane, Tolsa, Cristina Borradori, and Pfister, Riccardo

Published
2021
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5. Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort

Author

Alfaro Farias, Mario, Margarit, Antoni, Vizmanos-Lamotte, Gerardo, Tschoellitsch, Thomas, Meier, Jens, Cardona, Francesco S., Skola, Josef, Horakova, Lenka, Aguirre-Bermeo, Hernan, Apolo, Janina, Novy, Emmanuel, Losser, Marie-Reine, Jurkolow, Geoffrey, Delahaye, Gauthier, David, Sascha, Welte, Tobias, Wengenmayer, Tobias, Staudacher, Dawid L., Aslanidis, Theodoros, Babik, Barna, Korsos, Anita, Gal, Janos, Csaba, Hermann, Donati, Abele, Carsetti, Andrea, Turrini, Fabrizio, Simonini, Maria Sole, Ceriani, Roberto, Murrone, Martina, Rezoagli, Emanuele, Vitale, Giovanni, Fogagnolo, Alberto, Spadaro, Savino, Wu, Maddalena Alessandra, Cogliati, Chiara, Colombo, Riccardo, Catena, Emanuele, Facondini, Francesca, Potalivo, Antonella, Gangitano, Gianfilippo, Perin, Tiziana, Bocci, Maria Grazia, Antonelli, Massimo, Gommers, Diederik, Ince, Can, Mayor-Vázquez, Eric, Cruz, Maria, Delgado, Martin, Garcia, Raquel Rodriguez, Gamez Zapata, Jorge, Zalba-Etayo, Begoña, Lozano-Gomez, Herminia, Castro, Pedro, Tellez, Adrian, Jacas, Adriana, Muñoz, Guido, Andrea, Rut, Ortiz, Jose, Quintana, Eduard, Rovira, Irene, Reverter, Enric, Fernandez, Javier, Ferrer, Miquel, Badia, Joan R., Lander Azcona, Arantxa, Orta, Jesus Escos, Bühler, Philipp, Brugger, Silvio, Hofmaenner, Daniel, Unseld, Simone, Ruschitzka, Frank, Moret-Bochatay, Mallory, Yuen, Bernd, Hillermann, Thomas, Ksouri, Hatem, Sridharan, Govind Oliver, Ristic, Anette, Sepulcri, Michael, Filipovic, Miodrag, Pietsch, Urs, Salomon, Petra, Drvaric, Iris, Schott, Peter, Urech, Severin, Lambert, Adriana, Merki, Lukas, Laube, Marcus, Hillgaertner, Frank, Sieber, Marianne, Dullenkopf, Alexander, Petersen, Lina, Grazioli, Serge, Rimensberger, Peter C., Fleisch, Isabelle, Lavanchy, Jerome, Marquardt, Katharina, Shaikh, Karim, Redecker, Hermann, Stephan, Michael, Brem, Jan, Rogdo, Bjarte, Birkenmaier, Andre, Meyer zu Bentrup, Friederike, Fodor, Patricia, Locher, Pascal, Camen, Giovanni, Siegemund, Martin, Zellweger, Nuria, Jeitziner, Marie-Madlen, Jenni-Moser, Beatrice, Bürkle, Christian, Kleger, Gian-Reto, Franchitti Laurent, Marilene, Laurent, Jean-Christophe, Gaspert, Tomislav, Jovic, Marija, Studhalter, Michael, Haberthuer, Christoph, Lussman, Roger F., Selz, Daniela, Naon, Didier, Mauri, Romano, Ceruti, Samuele, Marrel, Julien, Brenni, Mirko, Ensner, Rolf, Gehring, Nadine, Heise, Antje, Huebner, Tobias, Neff, Thomas A., Cereghetti, Sara, Boroli, Filippo, Pugin, Jerome, Marczin, Nandor, Wong, Joyce, Wendel Garcia, Pedro David, Fumeaux, Thierry, Guerci, Philippe, Heuberger, Dorothea Monika, Montomoli, Jonathan, Roche-Campo, Ferran, Schuepbach, Reto Andreas, and Hilty, Matthias Peter

Published
2020
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6. Psychosocial outcomes in mothers and fathers of chronic critically ill children: a national prospective longitudinal study.

Author

Grandjean, Chantal, Rahmaty, Zahra, Perez, Marie-Hélène, Ramelet, Anne-Sylvie, Lauria, Anne-Laure, Polito, Angelo, Bochaton, Nathalie, Trachsel, Daniel, Marston, Mark, Schnidrig, Silvia, Humpl, Tilman, Rogdo, Bjarte, Wild, Ellen, Neuhaus, Thomas, Stalder, Sandra, Brotschi, Barbara, von Arx, Franziska, Schlüer, Anna-Barbara, Riedel, Thomas, and van Kleef, Pascale

Published
2024
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7. Anorexia nervosa im Kindes- und Jugendalter: Indikation zur Behandlung auf der Intensivstation

Author

Rutishauser, Christoph, Brotschi, Barbara; https://orcid.org/0000-0002-4472-5199, Hammer, Jürg, Laimbacher, Josef, Rogdo, Bjarte, Stade, Caroline, Wüthrich, Christian, di Gallo, Alain, Rutishauser, Christoph, Brotschi, Barbara; https://orcid.org/0000-0002-4472-5199, Hammer, Jürg, Laimbacher, Josef, Rogdo, Bjarte, Stade, Caroline, Wüthrich, Christian, and di Gallo, Alain

Abstract

Bei schwer kranken anorektischen Patientinnen und Patienten stellt sich die Frage nach einer temporären intensivmedizinischen Behandlung. Mit dem Ziel der Einigung über die Indikationsstellung hat eine Arbeitsgruppe aus Expertinnen und Experten der Deutschschweiz Empfehlungen ausgearbeitet.

Published
2023

8. Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial

Author

Welzel, Tatjana, primary, Atkinson, Andrew, additional, Schöbi, Nina, additional, Andre, Maya C, additional, Bailey, Douggl G N, additional, Blanchard-Rohner, Geraldine, additional, Buettcher, Michael, additional, Grazioli, Serge, additional, Koehler, Henrik, additional, Perez, Marie-Helene, additional, Trück, Johannes, additional, Vanoni, Federica, additional, Zimmermann, Petra, additional, Sanchez, Carlos, additional, Bielicki, Julia A, additional, Schlapbach, Luregn J, additional, Bieri, Andreas, additional, Gysi, Spyridoula, additional, Janz, Indra, additional, Donner, Birgit, additional, Hammer, Jürg, additional, Heininger, Ulrich, additional, Kohns Vasconcelos, Malte, additional, Mettauer, Nicole, additional, Meyer, Alexandra, additional, Reppucci, Diana, additional, Schlaeppi, Chloé, additional, Trachsel, Daniel, additional, Vaezipour, Nina, additional, von Kalckreuth, Clemens, additional, Woerner, Andreas, additional, Zutter, Andreas, additional, Kottanattu, Lisa, additional, Mazzara, Calogero, additional, Severi Conti, Alessia, additional, Aebi, Christoph, additional, Agyeman, Philipp K A, additional, Duppenthaler, Andrea, additional, Glöckler, Martin, additional, Pallivathukal, Sabine, additional, Riedel, Thomas, additional, Cudré-Cung, Hong-Phuc, additional, Pavlovic, Mladen, additional, Bordessoule, Alice, additional, L'Huillier, Arnaud G, additional, Martin, Anne-Laure, additional, Polito, Angelo, additional, Rohr, Marie, additional, Rodriguez, Maria Isabel, additional, Wagner, Noemie, additional, Chanez, Vivianne, additional, Bressieux-Degueldre, Sabrina, additional, Ferry, Thomas, additional, Hofer, Michael, additional, Longchamp, David, additional, Natterer, Julia, additional, Oppenheim, Rebecca, additional, Donas, Alex, additional, Germann, Sara, additional, Hrup, Katja, additional, Kaiser, Daniela, additional, Kuen, Hans Peter, additional, Lütolf Erni, Michaela, additional, Schwendener Scholl, Katharina, additional, Stritt, Janine, additional, Wechselberger, Katharina, additional, Beck, Ingrid, additional, Birkenmaier, André, additional, Flade, Martin, additional, Rogdo, Bjarte, additional, Iglowstein, Ivo, additional, Lorenz, Philip, additional, Wachinger, Tanja, additional, Zöhrer, Konstanze, additional, Brotschi, Barbara, additional, Meyer Sauteur, Patrick M, additional, Pachlopnik Schmid, Jana, additional, Prader, Seraina, additional, Seiler, Michelle, additional, Weber, Kathrin, additional, Wütz, Daniela, additional, Whittaker, Elizabeth, additional, and Faust, Saul N, additional

Published
2023
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9. Impact of SARS-CoV-2 on incidence, treatment and outcome of very preterm born infants in Switzerland: a retrospective, population-based cohort study

Author

Adams, Mark, Schulzke, Sven M, Rogdo, Bjarte, Meyer, Philipp, McDougall, Jane, Stocker, Martin, Schneider, Juliane, Riedel, Thomas, Pfister, Riccardo, Bassler, Dirk, Swiss Neonatal Network, University of Zurich, and Adams, Mark

Subjects
SARS, CoV, 610 Medicine & health, 2700 General Medicine, 10027 Clinic for Neonatology
Published
2022
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10. Impact of SARS-CoV-2 on incidence, treatment and outcome of very preterm born infants in Switzerland: a retrospective, population-based cohort study

Author

Adams, Mark; https://orcid.org/0000-0002-4645-2593, Schulzke, Sven M; https://orcid.org/0000-0002-5475-6239, Rogdo, Bjarte, Meyer, Philipp, McDougall, Jane, Stocker, Martin, Schneider, Juliane; https://orcid.org/0000-0001-6849-6178, Riedel, Thomas; https://orcid.org/0000-0002-7153-5251, Pfister, Riccardo, Bassler, Dirk, Swiss Neonatal Network, Adams, Mark; https://orcid.org/0000-0002-4645-2593, Schulzke, Sven M; https://orcid.org/0000-0002-5475-6239, Rogdo, Bjarte, Meyer, Philipp, McDougall, Jane, Stocker, Martin, Schneider, Juliane; https://orcid.org/0000-0001-6849-6178, Riedel, Thomas; https://orcid.org/0000-0002-7153-5251, Pfister, Riccardo, Bassler, Dirk, and Swiss Neonatal Network

Abstract

AIMS OF THE STUDY: To assess whether the COVID-19 pandemic caused by SARS-CoV-2 had an impact on incidence, treatment or major adverse short-term outcome of preterm-born infants in Switzerland. METHODS: Retrospective cohort study of preterm infants born in 2020 based on two independent data sources from the Swiss Federal Statistics Office (FSO) and SwissNeoNet. Based on FSO data, we calculated the odds ratios for extremely preterm (22-27 weeks gestation), very preterm (28-31 weeks gestation), and late preterm (32-36 weeks gestation) births during the pandemic. Based on SwissNeoNet data of infants born between 22 and 31 weeks gestation, we compared infants born during the Swiss lockdown period in 2020 with infants born during the same period between 2015 and 2019, all infants of 2020 with all infants between 2015 and 2019 and infants born to mothers tested SARS-CoV-2 positive and negative. Possible associations with the pandemic were tested using logistic regression adjusted for case-mix. As a control, we compared births of 2019 with those of 2015-2018. RESULTS: The FSO data revealed equivalent odds for extremely preterm births in 2020 (odds ratio [OR] 1.01, 95% confidence interval [CI] 0.89-1.14), as well as somewhat lower odds ratios for very preterm (OR 0.9, 95% CI 0.82-1.00) and late preterm (OR 0.91, 95% CI 0.88-0.93) births in 2020. A comparison between 2019 and 2015-2018, however, revealed matching odds ratios rendering an association to the pandemic unlikely. In the SwissNeoNet data, 137 infants were born during lockdown in 2020 compared with 134 births per year during 2015-2019. When including all infants, 744 infants were compared to 845 births, respectively. The only difference observed in treatments and short term outcomes between 2020 and the reference years were a higher odds for respiratory distress syndrome (OR 1.6, 95% CI 1.08-2.37) and provision of continuous positive airway pressure (CPAP) (OR 1.39, 95% CI 1.05-1.84). CONCLUSIONS: Our Swiss populat

Published
2022

12. Born into an Isolating World: Family-Centred Care for Babies Born to Mothers with COVID-19 the Epicentre Multinational Cohort Study

Author

Dowse, Georgie, primary, Perkins, Elizabeth, additional, Stein, Howard, additional, Chidini, Giovanna, additional, Danhaive, Olivier, additional, Elsayed, Yasser N., additional, de Carvalho, Werther Brunow, additional, Al-Naqeeb, Niran, additional, Rooze, Shancy, additional, Cetinkaya, Merih, additional, Vetter-Laracy, Susanne, additional, Pilar-Orive, Francisco Javier, additional, Torpiano, Paul, additional, Gonçalves-Ferri, Walusa Assad, additional, Buonsenso, Danilo, additional, Rogdo, Bjarte, additional, Medina, Alberto, additional, Polito, Angelo, additional, Brouwer, Carole, additional, Kneyber, Martin, additional, De Luca, Daniele, additional, and Tingay, David, additional

Published
2022
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14. Outcomes for Infants Born in Perinatal Centers Performing Fewer Surgical Ligations for Patent Ductus Arteriosus: A Swiss Population-Based Study

Author

Adams, Mark, primary, Schulzke, Sven M., additional, Natalucci, Giancarlo, additional, Schneider, Juliane, additional, Riedel, Thomas, additional, Tolsa, Cristina Borradori, additional, Pfister, Riccardo, additional, Bassler, Dirk, additional, Meyer, Philipp, additional, Kusche, Rachel, additional, Mori, Andrea Capone, additional, Kaeppeli, Daniela, additional, Brotzmann, Marc, additional, Ramelli, Gian Paolo, additional, Goeggel, Barbara Simonetti, additional, McDougall, Jane, additional, Humpl, Tilman, additional, Steinlin, Maja, additional, Grunt, Sebastian, additional, Gebauer, Mathias, additional, Hassink, Ralph, additional, Keller, Elmar, additional, Killer, Christa, additional, Blanchard, Gaelle, additional, Pfister, Riccardo E., additional, Huppi, Petra S., additional, Borradori-Tolsa, Cristina, additional, Tolsa, Jean-François, additional, Roth-Kleiner, Matthias, additional, Bickle-Graz, Myriam, additional, Stocker, Martin, additional, Schmitt-Mechelke, Thomas, additional, Bauder, Florian, additional, Erkert, Bernd, additional, Mueller, Anita, additional, Ecoffey, Marc, additional, Malzacher, Andreas, additional, Rogdo, Bjarte, additional, Lang-Dullenkopf, Anette, additional, Hegi, Lukas, additional, von Rhein, Michael, additional, Bernet, Vera, additional, Tomaske, Maren, additional, Arlettaz, Romaine, additional, Hagmann, Cornelia, additional, Latal, Bea, additional, and Etter, Ruth, additional

Published
2021
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15. Empfehlungen der IGPNI (Interessengemeinschaft für pädiatrische und neonatologische Intensivmedizin) zum Temperaturmanagement von pädiatrischen Patienten mit Hirnschädigungen auf der Intensivstation

Author

Brotschi, Barbara, Kelly, Janet Fiona, Rogdo, Bjarte, Stocker, Martin, Riedel, Tom, Humpel, Tilmann, Hammer, Jürg, Rimensberger, Peter, Perez, Marie-Hélène, Frey, Bernhard, and University of Zurich

Subjects
10036 Medical Clinic, 610 Medicine & health
Published
2020
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16. Outcomes for Infants Born in Perinatal Centers Performing Fewer Surgical Ligations for Patent Ductus Arteriosus: A Swiss Population-Based Study

Author

Adams, Mark; https://orcid.org/0000-0002-4645-2593, Schulzke, Sven M, Natalucci, Giancarlo, Schneider, Juliane; https://orcid.org/0000-0001-6849-6178, Riedel, Thomas; https://orcid.org/0000-0002-7153-5251, Tolsa, Cristina Borradori, Pfister, Riccardo, Bassler, Dirk, Meyer, Philipp, Kusche, Rachel, Mori, Andrea Capone, Kaeppeli, Daniela, Schulzke, Sven M; https://orcid.org/0000-0002-5475-6239, Brotzmann, Marc, Ramelli, Gian Paolo, Goeggel, Barbara Simonetti, McDougall, Jane, Humpl, Tilman, Steinlin, Maja, Grunt, Sebastian, Gebauer, Mathias, Hassink, Ralph, Riedel, Thomas, Keller, Elmar, Killer, Christa, Blanchard, Gaelle, Pfister, Riccardo E; https://orcid.org/0000-0002-7395-0512, Huppi, Petra S, Borradori-Tolsa, Cristina, Tolsa, Jean-François, Roth-Kleiner, Matthias, Bickle-Graz, Myriam, Stocker, Martin, Schmitt-Mechelke, Thomas, Bauder, Florian, Erkert, Bernd, Mueller, Anita, Ecoffey, Marc, Malzacher, Andreas, Rogdo, Bjarte, Lang-Dullenkopf, Anette, Hegi, Lukas, von Rhein, Michael, Bernet, Vera, Tomaske, Maren, Arlettaz, Romaine, Hagmann, Cornelia, Latal, Bea, Etter, Ruth, Adams, Mark; https://orcid.org/0000-0002-4645-2593, Schulzke, Sven M, Natalucci, Giancarlo, Schneider, Juliane; https://orcid.org/0000-0001-6849-6178, Riedel, Thomas; https://orcid.org/0000-0002-7153-5251, Tolsa, Cristina Borradori, Pfister, Riccardo, Bassler, Dirk, Meyer, Philipp, Kusche, Rachel, Mori, Andrea Capone, Kaeppeli, Daniela, Schulzke, Sven M; https://orcid.org/0000-0002-5475-6239, Brotzmann, Marc, Ramelli, Gian Paolo, Goeggel, Barbara Simonetti, McDougall, Jane, Humpl, Tilman, Steinlin, Maja, Grunt, Sebastian, Gebauer, Mathias, Hassink, Ralph, Riedel, Thomas, Keller, Elmar, Killer, Christa, Blanchard, Gaelle, Pfister, Riccardo E; https://orcid.org/0000-0002-7395-0512, Huppi, Petra S, Borradori-Tolsa, Cristina, Tolsa, Jean-François, Roth-Kleiner, Matthias, Bickle-Graz, Myriam, Stocker, Martin, Schmitt-Mechelke, Thomas, Bauder, Florian, Erkert, Bernd, Mueller, Anita, Ecoffey, Marc, Malzacher, Andreas, Rogdo, Bjarte, Lang-Dullenkopf, Anette, Hegi, Lukas, von Rhein, Michael, Bernet, Vera, Tomaske, Maren, Arlettaz, Romaine, Hagmann, Cornelia, Latal, Bea, and Etter, Ruth

Abstract

Objective To assess patent ductus arteriosus treatment variation between Swiss perinatal centers and to determine its effect on outcome in a population-based setting. Study design This was a retrospective cohort study of infants born less than 28 weeks of gestation between 2012 and 2017. Outcomes between surgically ligated and pharmacologically treated infants as well as infants born in centers performing ≤10% ligation (“low” group) and >10% (“high” group) were compared using logistic regression and 1:1 propensity score matching. Matching was based on case-mix and preligation confounders: intraventricular hemorrhages grades 3-4, necrotizing enterocolitis, sepsis, and ≥28 days’ oxygen supply. Results Of 1389 infants, 722 (52%) had pharmacologic treatment and 156 (11.2%) received surgical ligation. Compared with infants who received pharmacologic treatment, ligated infants had greater odds for major morbidities (OR 2.09, 95% CI 1.44-3.04) and 2-year neurodevelopmental impairment (OR 1.81, 95% CI 1.15-2.84). Mortality was comparable after restricting the cohort to infants surviving at least until day 10 to avoid survival bias. In the “low” group, 34 (4.9%) of 696 infants were ligated compared with 122 (17.6%) of 693 infants in the “high” group. Infants in the “high” group had greater odds for major morbidities (OR 1.49, 95% CI 1.11-2.0). Conclusions Our analysis identified a burden on infants receiving surgical ligation vs pharmacologic treatment in a population-based setting where there was no agreed-on common procedure. These results may guide a revision of patent ductus arteriosus treatment practice in Switzerland.

Published
2021

17. Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS; Multisystem Inflammatory Syndrome in Children, MIS-C) in Switzerland

Author

Schlapbach, Luregn J; https://orcid.org/0000-0003-2281-2598, Andre, Maya C, Grazioli, Serge; https://orcid.org/0000-0002-5526-851X, Schöbi, Nina, Ritz, Nicole; https://orcid.org/0000-0002-1498-1685, Aebi, Christoph; https://orcid.org/0000-0003-3554-7949, Agyeman, Philipp K A; https://orcid.org/0000-0002-8339-5444, Albisetti, Manuela, Bailey, Douggl G N, Berger, Christoph; https://orcid.org/0000-0002-1730-8824, Blanchard-Rohner, Geraldine; https://orcid.org/0000-0002-9974-2172, Bressieux-Degueldre, Sabrina, Hofer, Michael, L'Huillier, Arnaud G, Marston, Mark, Meyer Sauteur, Patrick M; https://orcid.org/0000-0002-4312-9803, Pachlopnik Schmid, Jana; https://orcid.org/0000-0002-6653-9047, Perez, Marie-Helene, Rogdo, Bjarte, Trück, Johannes; https://orcid.org/0000-0002-0418-7381, Woerner, Andreas, Wütz, Daniela; https://orcid.org/0000-0002-5186-2634, Zimmermann, Petra, Levin, Michael, Whittaker, Elizabeth, Rimensberger, Peter C, Schlapbach, Luregn J; https://orcid.org/0000-0003-2281-2598, Andre, Maya C, Grazioli, Serge; https://orcid.org/0000-0002-5526-851X, Schöbi, Nina, Ritz, Nicole; https://orcid.org/0000-0002-1498-1685, Aebi, Christoph; https://orcid.org/0000-0003-3554-7949, Agyeman, Philipp K A; https://orcid.org/0000-0002-8339-5444, Albisetti, Manuela, Bailey, Douggl G N, Berger, Christoph; https://orcid.org/0000-0002-1730-8824, Blanchard-Rohner, Geraldine; https://orcid.org/0000-0002-9974-2172, Bressieux-Degueldre, Sabrina, Hofer, Michael, L'Huillier, Arnaud G, Marston, Mark, Meyer Sauteur, Patrick M; https://orcid.org/0000-0002-4312-9803, Pachlopnik Schmid, Jana; https://orcid.org/0000-0002-6653-9047, Perez, Marie-Helene, Rogdo, Bjarte, Trück, Johannes; https://orcid.org/0000-0002-0418-7381, Woerner, Andreas, Wütz, Daniela; https://orcid.org/0000-0002-5186-2634, Zimmermann, Petra, Levin, Michael, Whittaker, Elizabeth, and Rimensberger, Peter C

Abstract

Background: Following the spread of the coronavirus disease 2019 (COVID-19) pandemic a new disease entity emerged, defined as Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflammatory Syndrome in Children (MIS-C). In the absence of trials, evidence for treatment remains scarce.Purpose: To develop best practice recommendations for the diagnosis and treatment of children with PIMS-TS in Switzerland. It is acknowledged that the field is changing rapidly, and regular revisions in the coming months are pre-planned as evidence is increasing.Methods: Consensus guidelines for best practice were established by a multidisciplinary group of Swiss pediatric clinicians with expertise in intensive care, immunology/rheumatology, infectious diseases, hematology, and cardiology. Subsequent to literature review, four working groups established draft recommendations which were subsequently adapted in a modified Delphi process. Recommendations had to reach >80% agreement for acceptance.Results: The group achieved agreement on 26 recommendations, which specify diagnostic approaches and interventions across anti-inflammatory, anti-infectious, and support therapies, and follow-up for children with suspected PIMS-TS. A management algorithm was derived to guide treatment depending on the phenotype of presentation, categorized into PIMS-TS with (a) shock, (b) Kawasaki-disease like, and (c) undifferentiated inflammatory presentation.Conclusion: Available literature on PIMS-TS is limited to retrospective or prospective observational studies. Informed by these cohort studies and indirect evidence from other inflammatory conditions in children and adults, as well as guidelines from international health authorities, the Swiss PIMS-TS recommendations represent best practice guidelines based on currently available knowledge to standardize treatment of children with suspected PIMS-TS. Given the absence of high-grade evidence, regular up

Published
2021

18. Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort

Author

Wendel Garcia, Pedro David, primary, Fumeaux, Thierry, additional, Guerci, Philippe, additional, Heuberger, Dorothea Monika, additional, Montomoli, Jonathan, additional, Roche-Campo, Ferran, additional, Schuepbach, Reto Andreas, additional, Hilty, Matthias Peter, additional, Alfaro Farias, Mario, additional, Margarit, Antoni, additional, Vizmanos-Lamotte, Gerardo, additional, Tschoellitsch, Thomas, additional, Meier, Jens, additional, Cardona, Francesco S., additional, Skola, Josef, additional, Horakova, Lenka, additional, Aguirre-Bermeo, Hernan, additional, Apolo, Janina, additional, Novy, Emmanuel, additional, Losser, Marie-Reine, additional, Jurkolow, Geoffrey, additional, Delahaye, Gauthier, additional, David, Sascha, additional, Welte, Tobias, additional, Wengenmayer, Tobias, additional, Staudacher, Dawid L., additional, Aslanidis, Theodoros, additional, Babik, Barna, additional, Korsos, Anita, additional, Gal, Janos, additional, Csaba, Hermann, additional, Donati, Abele, additional, Carsetti, Andrea, additional, Turrini, Fabrizio, additional, Simonini, Maria Sole, additional, Ceriani, Roberto, additional, Murrone, Martina, additional, Rezoagli, Emanuele, additional, Vitale, Giovanni, additional, Fogagnolo, Alberto, additional, Spadaro, Savino, additional, Wu, Maddalena Alessandra, additional, Cogliati, Chiara, additional, Colombo, Riccardo, additional, Catena, Emanuele, additional, Facondini, Francesca, additional, Potalivo, Antonella, additional, Gangitano, Gianfilippo, additional, Perin, Tiziana, additional, Bocci, Maria Grazia, additional, Antonelli, Massimo, additional, Gommers, Diederik, additional, Ince, Can, additional, Mayor-Vázquez, Eric, additional, Cruz, Maria, additional, Delgado, Martin, additional, Garcia, Raquel Rodriguez, additional, Gamez Zapata, Jorge, additional, Zalba-Etayo, Begoña, additional, Lozano-Gomez, Herminia, additional, Castro, Pedro, additional, Tellez, Adrian, additional, Jacas, Adriana, additional, Muñoz, Guido, additional, Andrea, Rut, additional, Ortiz, Jose, additional, Quintana, Eduard, additional, Rovira, Irene, additional, Reverter, Enric, additional, Fernandez, Javier, additional, Ferrer, Miquel, additional, Badia, Joan R., additional, Lander Azcona, Arantxa, additional, Orta, Jesus Escos, additional, Bühler, Philipp, additional, Brugger, Silvio, additional, Hofmaenner, Daniel, additional, Unseld, Simone, additional, Ruschitzka, Frank, additional, Moret-Bochatay, Mallory, additional, Yuen, Bernd, additional, Hillermann, Thomas, additional, Ksouri, Hatem, additional, Sridharan, Govind Oliver, additional, Ristic, Anette, additional, Sepulcri, Michael, additional, Filipovic, Miodrag, additional, Pietsch, Urs, additional, Salomon, Petra, additional, Drvaric, Iris, additional, Schott, Peter, additional, Urech, Severin, additional, Lambert, Adriana, additional, Merki, Lukas, additional, Laube, Marcus, additional, Hillgaertner, Frank, additional, Sieber, Marianne, additional, Dullenkopf, Alexander, additional, Petersen, Lina, additional, Grazioli, Serge, additional, Rimensberger, Peter C., additional, Fleisch, Isabelle, additional, Lavanchy, Jerome, additional, Marquardt, Katharina, additional, Shaikh, Karim, additional, Redecker, Hermann, additional, Stephan, Michael, additional, Brem, Jan, additional, Rogdo, Bjarte, additional, Birkenmaier, Andre, additional, Meyer zu Bentrup, Friederike, additional, Fodor, Patricia, additional, Locher, Pascal, additional, Camen, Giovanni, additional, Siegemund, Martin, additional, Zellweger, Nuria, additional, Jeitziner, Marie-Madlen, additional, Jenni-Moser, Beatrice, additional, Bürkle, Christian, additional, Kleger, Gian-Reto, additional, Franchitti Laurent, Marilene, additional, Laurent, Jean-Christophe, additional, Gaspert, Tomislav, additional, Jovic, Marija, additional, Studhalter, Michael, additional, Haberthuer, Christoph, additional, Lussman, Roger F., additional, Selz, Daniela, additional, Naon, Didier, additional, Mauri, Romano, additional, Ceruti, Samuele, additional, Marrel, Julien, additional, Brenni, Mirko, additional, Ensner, Rolf, additional, Gehring, Nadine, additional, Heise, Antje, additional, Huebner, Tobias, additional, Neff, Thomas A., additional, Cereghetti, Sara, additional, Boroli, Filippo, additional, Pugin, Jerome, additional, Marczin, Nandor, additional, and Wong, Joyce, additional

Published
2020
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19. Associations between red blood cell and platelet transfusions and retinopathy of prematurity

Author

Hengartner, Tobias, Adams, Mark, Pfister, Riccardo, Snyers, Diane, McDougall, Jane, Waldvogel, Salome, Held-Egli, Katrin, Spring, Lea, Rogdo, Bjarte, Riedel, Thomas, Arlettaz Mieth, Romaine, Swiss Neonatal Network, University of Zurich, and Hengartner, Tobias

Subjects
medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, 610 Medicine & health, Red blood cell transfusion, Logistic regression, Retinopathy of prematurity, 1309 Developmental Biology, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Medicine, Platelet, 2735 Pediatrics, Perinatology and Child Health, 030212 general & internal medicine, Prospective cohort study, Platelet transfusion, Original Paper, ddc:618, business.industry, Obstetrics, Gestational age, Odds ratio, 10027 Clinic for Neonatology, medicine.disease, Confidence interval, eye diseases, Pediatrics, Perinatology and Child Health, business, Developmental Biology
Abstract

Aim: The aim of this study is to examine possible associations between the transfusion of RBC or platelets (PLTs) and the development of retinopathy of prematurity (ROP) in infants. Methods: This retrospective, national, case-control study included all live births in Switzerland between 2013 and 2018. We investigated preterm infants at a gestational age of n = 178). Each case infant was matched to another of the same sex who did not develop ROP (n = 178, control group). Results: When compared with the control group, we observed higher numbers of RBC transfusions per infant and higher percentages of infants receiving PLT transfusions in the case group. An adjusted logistic regression analysis revealed that both RBC (odds ratio [OR] 1.081, 95% confidence interval [CI] 1.020–1.146) and PLT transfusions (OR = 2.502, 95% CI 1.566–3.998) numbers were associated with ROP development. Conclusions: Multiple RBC and PLT transfusions are associated with higher stage ROP development. Prospective studies are required to determine their potential as risk factors.

Published
2020

20. Community VersusVertically Acquired Neonatal SARS-CoV-2 Infection: The EPICENTRE Cohort Study

Author

De Luca, Daniele, Perkins, Elizabeth, Tingay, David G., Buonsenso, Danilo, Centorrino, Roberta, Vivanti, Alexandre, Rooze, Shancy, Pilar-Orive, Francisco J, Gonçalves-Ferri, Walusa Assad, Amigoni, Angela, de Carvalho, Werther Brunow, Jornada Krebs, Vera Lucia, AL-Naqeeb, Niran, Danhaive, Olivier, Cetinkaya, Merih, Stein, Howard, Shoemaker, Jessica, Danhaive, Olivier, Torpiano, Paul, Vetter-Laracy, Susanne, Rogdo, Bjarte, Elsayed, Yasser, Chidini, Giovanna, Kneyber, Martin, Medina Villanueva, Alberto, Polito, Angelo, Brouwer, Carole NM, and Rimensberger, Peter

Abstract

Neonatal Severe Acute Respiratory Syndrome-CoronaVirus-2 infections can be community-acquired or vertically-acquired. The analysis of neonatal patients requiring hospitalization reported in the EPICENTRE worldwide registry shows that community-acquired cases have clinical features (fever, respiratory signs, feeding difficulties, P< 0.0001) and received antibiotics (P= 0.014) more frequently than vertically-acquired patients. Severe Acute Respiratory Syndrome-CoronaVirus-2 infections should be considered in the clinical workout of neonatal infections.

Published
2023
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21. Empfehlungen der IGPNI (Interessengemeinschaft für pädiatrische und neonatologische Intensivmedizin) zum Temperaturmanagement von pädiatrischen Patienten mit Hirnschädigungen auf der Intensivstation

Author

Brotschi, Barbara; https://orcid.org/0000-0002-4472-5199, Kelly, Janet Fiona; https://orcid.org/0000-0002-1093-4822, Rogdo, Bjarte, Stocker, Martin, Riedel, Tom, Humpel, Tilmann, Hammer, Jürg, Rimensberger, Peter, Perez, Marie-Hélène, Frey, Bernhard, Brotschi, Barbara; https://orcid.org/0000-0002-4472-5199, Kelly, Janet Fiona; https://orcid.org/0000-0002-1093-4822, Rogdo, Bjarte, Stocker, Martin, Riedel, Tom, Humpel, Tilmann, Hammer, Jürg, Rimensberger, Peter, Perez, Marie-Hélène, and Frey, Bernhard

Published
2020

24. Giant omphalocele: current perspectives

Author

Rogdo, Bjarte and Mack,Alexander Josef

Subjects
Research and Reports in Neonatology
Abstract

Alexander Josef Mack,1 Bjarte Rogdo2 1Department of Pediatric Surgery, 2Pediatric and Neonatal Intensive Care Unit, Children’s Hospital of Eastern Switzerland, St Gallen, Switzerland Abstract: Giant omphalocele (GO) is a congenital ventral abdominal wall defect characterized by a large opening with herniated abdominal organs, including liver, loss of abdominal cavity volume, and other associated congenital anomalies. Treatment of patients with GO represents a major challenge for involved caregivers. Despite significant improvements in neonatal intensive and surgical care over the last decades, the condition is still associated with high mortality rates and a high risk of severe morbidity in survivors. The principles of the earliest attempts to treat GO surgically and conservatively are still easily recognized in the main approaches used today. In this review, we discuss the more recent developments in the treatment of GO, including perioperative management and associated morbidities of the condition. Keywords: giant omphalocele, abdominal wall closure, staged repair, delayed repair&nbsp

Published
2016

26. Giant omphalocele: current perspectives

Author

Mack,Alexander Josef, Rogdo,Bjarte, Mack,Alexander Josef, and Rogdo,Bjarte

Abstract

Alexander Josef Mack,1 Bjarte Rogdo2 1Department of Pediatric Surgery, 2Pediatric and Neonatal Intensive Care Unit, Children’s Hospital of Eastern Switzerland, St Gallen, Switzerland Abstract: Giant omphalocele (GO) is a congenital ventral abdominal wall defect characterized by a large opening with herniated abdominal organs, including liver, loss of abdominal cavity volume, and other associated congenital anomalies. Treatment of patients with GO represents a major challenge for involved caregivers. Despite significant improvements in neonatal intensive and surgical care over the last decades, the condition is still associated with high mortality rates and a high risk of severe morbidity in survivors. The principles of the earliest attempts to treat GO surgically and conservatively are still easily recognized in the main approaches used today. In this review, we discuss the more recent developments in the treatment of GO, including perioperative management and associated morbidities of the condition. Keywords: giant omphalocele, abdominal wall closure, staged repair, delayed repair&nbsp

Published
2016

29. Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS; Multisystem Inflammatory Syndrome in Children, MIS-C) in Switzerland.

Author

Schlapbach LJ, Andre MC, Grazioli S, Schöbi N, Ritz N, Aebi C, Agyeman P, Albisetti M, Bailey DGN, Berger C, Blanchard-Rohner G, Bressieux-Degueldre S, Hofer M, L'Huillier AG, Marston M, Meyer Sauteur PM, Pachlopnik Schmid J, Perez MH, Rogdo B, Trück J, Woerner A, Wütz D, Zimmermann P, Levin M, Whittaker E, and Rimensberger PC

Abstract

Background: Following the spread of the coronavirus disease 2019 (COVID-19) pandemic a new disease entity emerged, defined as Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflammatory Syndrome in Children (MIS-C). In the absence of trials, evidence for treatment remains scarce. Purpose: To develop best practice recommendations for the diagnosis and treatment of children with PIMS-TS in Switzerland. It is acknowledged that the field is changing rapidly, and regular revisions in the coming months are pre-planned as evidence is increasing. Methods: Consensus guidelines for best practice were established by a multidisciplinary group of Swiss pediatric clinicians with expertise in intensive care, immunology/rheumatology, infectious diseases, hematology, and cardiology. Subsequent to literature review, four working groups established draft recommendations which were subsequently adapted in a modified Delphi process. Recommendations had to reach >80% agreement for acceptance. Results: The group achieved agreement on 26 recommendations, which specify diagnostic approaches and interventions across anti-inflammatory, anti-infectious, and support therapies, and follow-up for children with suspected PIMS-TS. A management algorithm was derived to guide treatment depending on the phenotype of presentation, categorized into PIMS-TS with (a) shock, (b) Kawasaki-disease like, and (c) undifferentiated inflammatory presentation. Conclusion: Available literature on PIMS-TS is limited to retrospective or prospective observational studies. Informed by these cohort studies and indirect evidence from other inflammatory conditions in children and adults, as well as guidelines from international health authorities, the Swiss PIMS-TS recommendations represent best practice guidelines based on currently available knowledge to standardize treatment of children with suspected PIMS-TS. Given the absence of high-grade evidence, regular updates of the recommendations will be warranted, and participation of patients in trials should be encouraged., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Schlapbach, Andre, Grazioli, Schöbi, Ritz, Aebi, Agyeman, Albisetti, Bailey, Berger, Blanchard-Rohner, Bressieux-Degueldre, Hofer, L'Huillier, Marston, Meyer Sauteur, Pachlopnik Schmid, Perez, Rogdo, Trück, Woerner, Wütz, Zimmermann, Levin, Whittaker, Rimensberger and the PIMS-TS working group of the Interest Group for Pediatric Neonatal Intensive Care (IGPNI) of the Swiss Society of Intensive Care and the Pediatric Infectious Diseases Group Switzerland (PIGS).)

Published
2021
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