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4. Straßenverkehrsrecht

Author

Schöch, H., Rösler, M., Kröber, Hans-Ludwig, editor, Dölling, Dieter, editor, Leygraf, Norbert, editor, and Sass, Henning, editor

Published
2009
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7. Toward Precision Medicine in ADHD

Author

Buitelaar, J.K., Bölte, S., Brandeis, D., Caye, A., Christmann, N., Cortese, S., Coghill, D., Faraone, S.V, Franke, B., Gleitz, M., Greven, C.U., Kooij, S., Leffa, D.T., Rommelse, N.N.J., Newcorn, J.H., Polanczyk, G.V., Rohde, L.A., Simonoff, E., Stein, M., Vitiello, B., Yazgan, Y., Roesler, M., Doepfner, M., Banaschewski, T., Buitelaar, J.K., Bölte, S., Brandeis, D., Caye, A., Christmann, N., Cortese, S., Coghill, D., Faraone, S.V, Franke, B., Gleitz, M., Greven, C.U., Kooij, S., Leffa, D.T., Rommelse, N.N.J., Newcorn, J.H., Polanczyk, G.V., Rohde, L.A., Simonoff, E., Stein, M., Vitiello, B., Yazgan, Y., Roesler, M., Doepfner, M., and Banaschewski, T.

Abstract

Contains fulltext : 281503.pdf (Publisher’s version ) (Open Access), Attention-Deficit Hyperactivity Disorder (ADHD) is a complex and heterogeneous neurodevelopmental condition for which curative treatments are lacking. Whilst pharmacological treatments are generally effective and safe, there is considerable inter-individual variability among patients regarding treatment response, required dose, and tolerability. Many of the non-pharmacological treatments, which are preferred to drug-treatment by some patients, either lack efficacy for core symptoms or are associated with small effect sizes. No evidence-based decision tools are currently available to allocate pharmacological or psychosocial treatments based on the patient's clinical, environmental, cognitive, genetic, or biological characteristics. We systematically reviewed potential biomarkers that may help in diagnosing ADHD and/or stratifying ADHD into more homogeneous subgroups and/or predict clinical course, treatment response, and long-term outcome across the lifespan. Most work involved exploratory studies with cognitive, actigraphic and EEG diagnostic markers to predict ADHD, along with relatively few studies exploring markers to subtype ADHD and predict response to treatment. There is a critical need for multisite prospective carefully designed experimentally controlled or observational studies to identify biomarkers that index inter-individual variability and/or predict treatment response.

Published
2022

8. Toward Precision Medicine in ADHD.

Author

Buitelaar, J, Bölte, S, Brandeis, D, Caye, A, Christmann, N, Cortese, S, Coghill, D, Faraone, SV, Franke, B, Gleitz, M, Greven, CU, Kooij, S, Leffa, DT, Rommelse, N, Newcorn, JH, Polanczyk, GV, Rohde, LA, Simonoff, E, Stein, M, Vitiello, B, Yazgan, Y, Roesler, M, Doepfner, M, Banaschewski, T, Buitelaar, J, Bölte, S, Brandeis, D, Caye, A, Christmann, N, Cortese, S, Coghill, D, Faraone, SV, Franke, B, Gleitz, M, Greven, CU, Kooij, S, Leffa, DT, Rommelse, N, Newcorn, JH, Polanczyk, GV, Rohde, LA, Simonoff, E, Stein, M, Vitiello, B, Yazgan, Y, Roesler, M, Doepfner, M, and Banaschewski, T

Abstract

Attention-Deficit Hyperactivity Disorder (ADHD) is a complex and heterogeneous neurodevelopmental condition for which curative treatments are lacking. Whilst pharmacological treatments are generally effective and safe, there is considerable inter-individual variability among patients regarding treatment response, required dose, and tolerability. Many of the non-pharmacological treatments, which are preferred to drug-treatment by some patients, either lack efficacy for core symptoms or are associated with small effect sizes. No evidence-based decision tools are currently available to allocate pharmacological or psychosocial treatments based on the patient's clinical, environmental, cognitive, genetic, or biological characteristics. We systematically reviewed potential biomarkers that may help in diagnosing ADHD and/or stratifying ADHD into more homogeneous subgroups and/or predict clinical course, treatment response, and long-term outcome across the lifespan. Most work involved exploratory studies with cognitive, actigraphic and EEG diagnostic markers to predict ADHD, along with relatively few studies exploring markers to subtype ADHD and predict response to treatment. There is a critical need for multisite prospective carefully designed experimentally controlled or observational studies to identify biomarkers that index inter-individual variability and/or predict treatment response.

Published
2022

11. Metrifonat

Author

Retz, W., Rösler, M., Riederer, Peter, editor, Laux, Gerd, editor, and Pöldinger, Walter, editor

Published
1999
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12. Galanthamin

Author

Rösler, M., Riederer, Peter, editor, Laux, Gerd, editor, and Pöldinger, Walter, editor

Published
1999
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13. Propentofyllin

Author

Rösler, M., Riederer, Peter, editor, Laux, Gerd, editor, and Pöldinger, Walter, editor

Published
1999
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14. Rivastigmin

Author

Enz, A., Rösler, M., Riederer, Peter, editor, Laux, Gerd, editor, and Pöldinger, Walter, editor

Published
1999
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34. Identification of a salt-induced primary transporter for glycine betaine in the methanogen Methanosarcina mazei Go1

Author

Roesler, M., Pfluger, K., Flach, H., Lienard, T., Gottschalk, G., and Muller, V.

Subjects
Methanobacteriaceae -- Research, Osmoregulation -- Research, Biological sciences
Abstract

The first known salt-induced glycine betaine transporter protein in Archaea is described. It was discovered in Methanosarcina mazei Go1 and is similar to the glycine betaine transporter OpuA of Bacillus subtilis.

Published
2002

49. First World Congress on Trophoblast Neoplasms

Author

Berkowitz, R. S., Lahey, S. J., Steele, G., Jr., Rayner, A. A., Rodrick, M. L., Goldstein, D. P., Harahap, R., Pattillo, R. A., Sasaki, S., Katayama, K. P., Roesler, M., Mattingly, R. F., Zucker, P. K., Bernstein, M. R., Salari, H., Partovie, V., Shin, M. W., Rao, Ch. V., Hussa, R. O., Carman, F. R., Jr., Rinke, M. L., Cook, C. L., Yussman, M. A., Zakut, H., Ludomirsky, A., Cole, L. A., Sutphen, S. K., Kim, S. J., Kang, B. C., Jung, J. K., Lee, J. W., Sekadde-Kigondu, C. B., Mati, J. K. G., Mokohka, A. E., Fongoh, F. B., Lequin, R. M., Tanaka, T., Ito, H., Hosokawa, T., Elegbe, R. A., Damole, I. O., Hoffmann, R. G., Finlayson, W., Jones, W. B., Stanimir, G. W., Lewis, J. L., Jr., Birnholz, J., Hsu, C. T., Sarram, M., Baja-Panlilio, H., Lopez, A. M., Huy, I. C., Aartsen, E. J., Lammes, F. B., ten Kate Booy, M. J., Ng, Heung Tat, Partovi, V., Nassirai, G. H., Martaadisoebrata, Djamhoer, Pattillo, Roland A., editor, and Hussa, Robert O., editor

Published
1984
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