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2. PBM: Now more than ever necessary

Author

García-Erce, J.A., Jericó, C., Abad-Motos, A., Rodríguez García, J., Antelo Caamaño, M.L., Domingo Morera, J.M., Sola Lapeña, C., Arroyo, J.L., Fernández Fuertes, F., Zalba Marcos, S., Cerdán Rodríguez, G., Laso Morales, M.J., Bueno Cabrera, J.L., Chica, E., Recasens, V., Zabalegui, A., Balen, E., Urrechaga, E., Abad-Gurumeta, A., and Quintana Díaz, M.

Published
2022
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3. PBM: Ahora más que nunca es necesario

Author

García-Erce, J.A., Jericó, C., Abad-Motos, A., Rodríguez García, J., Antelo Caamaño, M.L., Domingo Morera, J.M., Sola Lapeña, C., Arroyo, J.L., Fernández Fuertes, F., Zalba Marcos, S., Cerdán Rodríguez, G., Laso Morales, M.J., Bueno Cabrera, J.L., Chica, E., Recasens, V., Zabalegui, A., Balen, E., Urrechaga, E., Abad-Gurumeta, A., and Quintana Díaz, M.

Published
2022
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5. Recommendations for vaccination in patients with multiple sclerosis who are eligible for immunosuppressive therapies: Spanish consensus statement

Author

Otero-Romero, S., Rodríguez-García, J., Vilella, A., Ara, J.R., Brieva, L., Calles, C., Carmona, O., Casanova, V., Costa-Frossard, L., Eichau, S., García-Merino, J.A., Garcia-Vidal, C., González-Platas, M., Llaneza, M., Martínez-Ginés, M., Meca-Lallana, J.E., Prieto, J.M., Rodríguez-Antigüedad, A., Tintoré, M., Blanco, Y., and Moral, E.

Published
2021
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6. Recomendaciones para la vacunación en pacientes con esclerosis múltiple candidatos a terapias inmunosupresoras: documento de consenso español

Author

Otero-Romero, S., Rodríguez-García, J., Vilella, A., Ara, J.R., Brieva, L., Calles, C., Carmona, O., Casanova, V., Costa-Frossard, L., Eichau, S., García-Merino, J.A., Garcia-Vidal, C., González-Platas, M., Llaneza, M., Martínez-Ginés, M., Meca-Lallana, J.E., Prieto, J.M., Rodríguez-Antigüedad, A., Tintoré, M., Blanco, Y., and Moral, E.

Published
2021
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10. The major upgrade of the MAGIC telescopes, Part I: The hardware improvements and the commissioning of the system

Author

Aleksić, J., Ansoldi, S., Antonelli, L.A., Antoranz, P., Babic, A., Bangale, P., Barceló, M., Barrio, J.A., Becerra González, J., Bednarek, W., Bernardini, E., Biasuzzi, B., Biland, A., Bitossi, M., Blanch, O., Bonnefoy, S., Bonnoli, G., Borracci, F., Bretz, T., Carmona, E., Carosi, A., Cecchi, R., Colin, P., Colombo, E., Contreras, J.L., Corti, D., Cortina, J., Covino, S., Da Vela, P., Dazzi, F., DeAngelis, A., De Caneva, G., De Lotto, B., de Oña Wilhelmi, E., Delgado Mendez, C., Dettlaff, A., Dominis Prester, D., Dorner, D., Doro, M., Einecke, S., Eisenacher, D., Elsaesser, D., Fidalgo, D., Fink, D., Fonseca, M.V., Font, L., Frantzen, K., Fruck, C., Galindo, D., García López, R.J., Garczarczyk, M., Garrido Terrats, D., Gaug, M., Giavitto, G., Godinović, N., González Muñoz, A., Gozzini, S.R., Haberer, W., Hadasch, D., Hanabata, Y., Hayashida, M., Herrera, J., Hildebrand, D., Hose, J., Hrupec, D., Idec, W., Illa, J.M., Kadenius, V., Kellermann, H., Knoetig, M.L., Kodani, K., Konno, Y., Krause, J., Kubo, H., Kushida, J., La Barbera, A., Lelas, D., Lemus, J.L., Lewandowska, N., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Coto, R., López-Oramas, A., Lorca, A., Lorenz, E., Lozano, I., Makariev, M., Mallot, K., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Marcote, B., Mariotti, M., Martínez, M., Mazin, D., Menzel, U., Miranda, J.M., Mirzoyan, R., Moralejo, A., Munar-Adrover, P., Nakajima, D., Negrello, M., Neustroev, V., Niedzwiecki, A., Nilsson, K., Nishijima, K., Noda, K., Orito, R., Overkemping, A., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J.M., Paredes-Fortuny, X., Persic, M., Poutanen, J., Prada Moroni, P.G., Prandini, E., Puljak, I., Reinthal, R., Rhode, W., Ribó, M., Rico, J., Rodriguez Garcia, J., Rügamer, S., Saito, T., Saito, K., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schlammer, J., Schmidl, S., Schweizer, T., Sillanpää, A., Sitarek, J., Snidaric, I., Sobczynska, D., Spanier, F., Stamerra, A., Steinbring, T., Storz, J., Strzys, M., Takalo, L., Takami, H., Tavecchio, F., Tejedor, L.A., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Thaele, J., Tibolla, O., Torres, D.F., Toyama, T., Treves, A., Vogler, P., Wetteskind, H., Will, M., and Zanin, R.

Published
2016
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11. The major upgrade of the MAGIC telescopes, Part II: A performance study using observations of the Crab Nebula

Author

Aleksić, J., Ansoldi, S., Antonelli, L.A., Antoranz, P., Babic, A., Bangale, P., Barceló, M., Barrio, J.A., Becerra González, J., Bednarek, W., Bernardini, E., Biasuzzi, B., Biland, A., Bitossi, M., Blanch, O., Bonnefoy, S., Bonnoli, G., Borracci, F., Bretz, T., Carmona, E., Carosi, A., Cecchi, R., Colin, P., Colombo, E., Contreras, J.L., Corti, D., Cortina, J., Covino, S., Da Vela, P., Dazzi, F., De Angelis, A., De Caneva, G., De Lotto, B., de Oña Wilhelmi, E., Delgado Mendez, C., Dettlaff, A., Dominis Prester, D., Dorner, D., Doro, M., Einecke, S., Eisenacher, D., Elsaesser, D., Fidalgo, D., Fink, D., Fonseca, M.V., Font, L., Frantzen, K., Fruck, C., Galindo, D., García López, R.J., Garczarczyk, M., Garrido Terrats, D., Gaug, M., Giavitto, G., Godinović, N., González Muñoz, A., Gozzini, S.R., Haberer, W., Hadasch, D., Hanabata, Y., Hayashida, M., Herrera, J., Hildebrand, D., Hose, J., Hrupec, D., Idec, W., Illa, J.M., Kadenius, V., Kellermann, H., Knoetig, M.L., Kodani, K., Konno, Y., Krause, J., Kubo, H., Kushida, J., La Barbera, A., Lelas, D., Lemus, J.L., Lewandowska, N., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Coto, R., López-Oramas, A., Lorca, A., Lorenz, E., Lozano, I., Makariev, M., Mallot, K., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Marcote, B., Mariotti, M., Martínez, M., Mazin, D., Menzel, U., Miranda, J.M., Mirzoyan, R., Moralejo, A., Munar-Adrover, P., Nakajima, D., Negrello, M., Neustroev, V., Niedzwiecki, A., Nilsson, K., Nishijima, K., Noda, K., Orito, R., Overkemping, A., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J.M., Paredes-Fortuny, X., Persic, M., Poutanen, J., Prada Moroni, P.G., Prandini, E., Puljak, I., Reinthal, R., Rhode, W., Ribó, M., Rico, J., Rodriguez Garcia, J., Rügamer, S., Saito, T., Saito, K., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schlammer, J., Schmidl, S., Schweizer, T., Shore, S.N., Sillanpää, A., Sitarek, J., Snidaric, I., Sobczynska, D., Spanier, F., Stamerra, A., Steinbring, T., Storz, J., Strzys, M., Takalo, L., Takami, H., Tavecchio, F., Tejedor, L.A., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Thaele, J., Tibolla, O., Torres, D.F., Toyama, T., Treves, A., Vogler, P., Wetteskind, H., Will, M., and Zanin, R.

Published
2016
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13. Measurement of the Crab Nebula spectrum over three decades in energy with the MAGIC telescopes

Author

Aleksić, J., Ansoldi, S., Antonelli, L.A., Antoranz, P., Babic, A., Bangale, P., Barrio, J.A., Becerra González, J., Bednarek, W., Bernardini, E., Biasuzzi, B., Biland, A., Blanch, O., Bonnefoy, S., Bonnoli, G., Borracci, F., Bretz, T., Carmona, E., Carosi, A., Colin, P., Colombo, E., Contreras, J.L., Cortina, J., Covino, S., Da Vela, P., Dazzi, F., De Angelis, A., De Caneva, G., De Lotto, B., de Oña Wilhelmi, E., Delgado Mendez, C., Doert, M., Dominis Prester, D., Dorner, D., Doro, M., Einecke, S., Eisenacher, D., Elsaesser, D., Fonseca, M.V., Font, L., Frantzen, K., Fruck, C., Galindo, D., García López, R.J., Garczarczyk, M., Garrido Terrats, D., Gaug, M., Godinović, N., González Muñoz, A., Gozzini, S.R., Hadasch, D., Hanabata, Y., Hayashida, M., Herrera, J., Hildebrand, D., Hose, J., Hrupec, D., Idec, W., Kadenius, V., Kellermann, H., Kodani, K., Konno, Y., Krause, J., Kubo, H., Kushida, J., La Barbera, A., Lelas, D., Lewandowska, N., Lindfors, E., Lombardi, S., López, M., López-Coto, R., López-Oramas, A., Lorenz, E., Lozano, I., Makariev, M., Mallot, K., Maneva, G., Mankuzhiyil, N., Mannheim, K., Maraschi, L., Marcote, B., Mariotti, M., Martínez, M., Mazin, D., Menzel, U., Miranda, J.M., Mirzoyan, R., Moralejo, A., Munar-Adrover, P., Nakajima, D., Niedzwiecki, A., Nilsson, K., Nishijima, K., Noda, K., Nowak, N., Orito, R., Overkemping, A., Paiano, S., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J.M., Paredes-Fortuny, X., Persic, M., Prada Moroni, P.G., Prandini, E., Preziuso, S., Puljak, I., Reinthal, R., Rhode, W., Ribó, M., Rico, J., Rodriguez Garcia, J., Rügamer, S., Saggion, A., Saito, T., Saito, K., Satalecka, K., Scalzotto, V., Scapin, V., Schultz, C., Schweizer, T., Shore, S.N., Sillanpää, A., Sitarek, J., Snidaric, I., Sobczynska, D., Spanier, F., Stamatescu, V., Stamerra, A., Steinbring, T., Storz, J., Strzys, M., Takalo, L., Takami, H., Tavecchio, F., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Thaele, J., Tibolla, O., Torres, D.F., Toyama, T., Treves, A., Uellenbeck, M., Vogler, P., Wagner, R.M., Zanin, R., Horns, D., Martín, J., and Meyer, M.

Published
2015
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23. Synthesis and mechanical characterization of hydroxyapatite-based biomaterials reinforced with nickel-titanium-magnesium alloys for use in cortical bone implants

Author

Refugio-García María E., Miranda-Hernández José G., Gallardo-Mendez Marco A., Vázquez-Huerta Gerardo, Rodríguez-García José A., and Rocha-Rangel Enrique

Subjects
hidroxiapatite, nickel-titanium-magnesium, biomaterial, bone implants, Chemical technology, TP1-1185
Abstract

In this work, biomaterials consisting of bioactive hydroxyapatite-based ceramic and nickel-titanium-magnesium alloys were made. The biomaterials were obtained through powder techniques involving mechanical milling, uniaxial pressing and pressureless sintering. The purpose of the study was to evaluate the effect of alloys on the mechanical properties of hydroxyapatite, the alloy additions were 0, 20, 30, 40, 40, 50 and 60 wt.%. The results were compared with cortical bone samples of bovine origin. From the results, it is possible to comment that, with increasing alloy contents in the hydroxyapatite, the mechanical properties increase considerably. The behavior of the composites reinforced with 50 and 60 wt.% NiTiMg alloy is similar to that of bovine cortical bone. The microstructures of the biomaterials are fine, homogeneous, and similar to those of bovine cortical bone. From the study it can be commented that given the mechanical characteristics of the biomaterials obtained, they could be used as possible bone implants.

Published
2024
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35. Variations in threshold values for border zone and dense scar produce significant changes in scar parameters obtained by ADAS-3D.

Author

Faga V, Dallaglio PD, Claver E, Rodriguez-García J, San Antonio R, Rodriguez M, Payan C, Comin-Colet J, Anguera I, and Di Marco A

Subjects
Humans, Female, Male, Retrospective Studies, Middle Aged, Catheter Ablation methods, Imaging, Three-Dimensional methods, Aged, Myocardial Infarction physiopathology, Software, Myocardium pathology, Cicatrix physiopathology, Cicatrix diagnostic imaging, Cicatrix diagnosis, Magnetic Resonance Imaging, Cine methods, Tachycardia, Ventricular physiopathology, Tachycardia, Ventricular diagnosis
Abstract

Background: ADAS-3D software elaborates cardiac magnetic resonance (CMR) images to obtain a quantitative evaluation of dense scar and border zone (BZ), including BZ channels, which can be useful for ventricular tachycardia ablation and risk stratification. However, most prior reports with ADAS-3D used flexible thresholds (60% ± 5% and 40% ± 5% of maximum pixel signal intensity) to define dense scar and BZ. The impact of such variations of the threshold values on the measurements obtained with ADAS-3D is unknown., Objective: This study aimed to quantify the degree of change in ADAS-3D measurements when different thresholds for dense scar and BZ are employed., Methods: A single-center retrospective observational cohort study including 87 consecutive patients with previous myocardial infarction who underwent CMR was conducted. ADAS-3D software semiautomatically processed CMR sequences. We compared the scar measurements obtained with the 9 possible combinations of thresholds (55%/60%/65% and 35%/40%/45% of maximum pixel signal intensity)., Results: The overall comparison between thresholds showed highly significant differences (P < .001) in all scar parameters. Not a single patient maintained the same number of BZ channels with all the thresholds settings. A percentage difference of up to 200% in BZ channel numbers and channel mass was observed in all 36 comparisons. An absolute difference of up to 10 channels was also recorded. Of note, the highest median channel mass (obtained with the thresholds 35-65) was 59-fold higher compared with the lowest one (obtained with the 45-55 cutoffs)., Conclusion: Variations in threshold values result in statistically significant and high-magnitude changes in the quantification of scar parameters by ADAS-3D., (Copyright © 2024 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.)

Published
2025
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36. Late gadolinium enhancement and outcome of cardiac resynchronization therapy in non-ischemic cardiomyopathy.

Author

Anguera I, Faga V, Jimenez-Candil J, Moreno-Weidmann Z, Santos-Ortega A, Jimenez-Jaimez J, Rodriguez-García J, Claver E, Mercé J, Jovells-Vaque S, Diez-Lopez C, Hernández J, Rivas-Gandara N, Macías R, García-Cosculluela D, Comin-Colet J, and Di Marco A

Subjects
Humans, Female, Male, Retrospective Studies, Middle Aged, Aged, Treatment Outcome, Follow-Up Studies, Contrast Media, Cardiac Resynchronization Therapy methods, Cardiomyopathies therapy, Cardiomyopathies diagnostic imaging, Gadolinium, Magnetic Resonance Imaging, Cine methods
Abstract

Background: It is uncertain whether CRT with defibrillator (CRTD) is superior to CRT with pacemaker (CRTP) in NICM. Patients with low arrhythmic risk and high probability of response to CRT might be ideal candidates for CRTP. We aimed to evaluate predictors of ventricular arrhythmias and of echocardiographic response to cardiac resynchronization therapy (CRT) in non-ischemic cardiomyopathy (NICM)., Methods: Multicenter, retrospective observational study of NICM patients with left ventricular ejection fraction (LVEF) ≤35 %, cardiac magnetic resonance with analysis of late gadolinium enhancement (LGE) available and de-novo CRT implant. Echocardiographic response to CRT was defined as an improvement in LVEF ≥10 %. The combined arrhythmic endpoint included sustained ventricular tachycardia, appropriate ICD therapy, resuscitated cardiac arrest and sudden death., Results: We included 167 patients, with a median follow-up of 63 months. LGE was present in 77 (46 %). Response to CRT occurred in 68 % of patients, more frequently in LGE- than in LGE+ (81 % vs 53 %, p < 0.001). Absence of LGE (OR 3.4, p = 0.002), was an independent predictor of response to CRT. The arrhythmic endpoint occurred in 19 patients (11 %). Among LGE- patients there were zero arrhythmic events as compared to a 25 % cumulative incidence in LGE+ (p < 0.001). Presence of LGE (HR 22.5, p < 0.001), was an independent predictor of the arrhythmic endpoint., Conclusion: Absence of LGE identifies patients at minimal arrhythmic risk and with high probability of response to CRT. Thus, they might be ideal candidates to CRT-P., (Copyright © 2024 Elsevier B.V. All rights reserved.)

Published
2025
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37. [Position of the international forum of internal medicine on habits, lifestyle changes and a healthy environment for the prevention of cardiovascular diseases].

Author

Sabio R, Valdez P, Nachón MN, Arias C, Nitsch Montiel C, Penny E, Melgar Cuellar F, Araya Fonseca C, Montúfar Guardado R, Cotignola Á, Odzak A, Franchella J, Bisso A, Duran M, Palencia Vizcarra R, Gómez Huelgas R, Rodríguez W, Milione H, Parodi R, Buchaca Faxas E, Rojas Orellana L, Fortuna Peralta ML, Coral Cristaldo C, Ortellado J, Diez Manglano J, Barrios J, Jiménez MC, Gutiérrez Tudela J, Bruno G, Contreras Mónchez J, Payaslián S, Pollán J, Hernández H, Vaucher A, Betancourt I, Codina H, Celauro H, Cortese S, Risso M, Puello H, Casariego E, Díaz Salazar L, García Peña R, Indacochea-Cáceda S, García-Carrión L, Murillo Salvatierra E, Mirofsky M, Andrade G, Savia A, Canda P, Cárdenas A, Rodríguez Hurtado D, Chimeno Viñas M, Patiño M, Gómez Mendoza R, Arbo G, Romano HJ, Sánchez Cabezas A, Abuabara Turbay Y, Hiza R, Campos L, Do Patrocinio Tenorio Nunes M, Santos L, Salazar Matos V, Espinosa T, González Ruiz Díaz J, Carrasco S, Romani A, Escalera L, Palencia Díaz R, Giaccaglia G, Galarza Nuñez J, Román Sánchez P, Costanzo M, Garay Tamara S, Rodriguez García J, Bellini O, Ruiz Cantero A, Cámera L, Serra Valdés M, Ledesma R, Blanco Aspiazu M, Mejía Terrero A, Arango Álvarez JJ, Cárcamo De Villatoro KE, Castillo Fernández O, Monteghirfo R, Galarza C, Somoza F, Schejtman A, Perez B, Marconi A, and Cabrera Rayo A

Subjects
Humans, Habits, Life Style, Environmental Health, Internal Medicine, Cardiovascular Diseases prevention & control
Abstract

Cardiovascular diseases (CVD), mainly ischemic heart disease and stroke, is the main cause of death worldwide and each year more people die from CVD than from any other cause. These data call for a paradigm shift, where health promotion and cardiovascular prevention will acquire a central role in health policies. From this perspective, dedicating time during the consultation to promoting the acquisition of heart-healthy habits would be indicated in all individuals, regardless of cardiovascular risk classification, the role of the internist being fundamental. This position document from the International Forum of Internal Medicine (FIMI) presents the main indications regarding changes in lifestyle and acquisition of healthy habits to prevent CVD. The different sections will address topics including: nutrition, physical activity, sedentary lifestyle, obesity, smoking, alcohol consumption, sleep, stress, environmental problems related to CVD and specific conditions in women. A section is included about starting CVD promotion and prevention measures at an early age, childhood and adolescence, also mentioning epigenetic aspects related to CVD. Social determinants in CVD are also taken into account, since some of these aspects, such as low socioeconomic level, modify cardiovascular risk and should be taken into account.

Published
2023

38. Improved prediction of electrical storm in patients with prior myocardial infarction and implantable cardioverter defibrillator.

Author

Faga V, Anguera I, Oloriz T, Nombela-Franco L, Teruel L, Dallaglio P, Perez Guerrero A, Hernando Salazar C, Escaned J, Asso Abadía A, Gomez Hospital JA, Rodriguez García J, Rodriguez García M, Comin Colet J, and Di Marco A

Subjects
Arrhythmias, Cardiac diagnosis, Humans, Risk Factors, Treatment Outcome, Defibrillators, Implantable, Myocardial Infarction diagnosis, Myocardial Infarction epidemiology, Myocardial Infarction therapy, Tachycardia, Ventricular diagnostic imaging, Tachycardia, Ventricular epidemiology
Abstract

Aims: To evaluate predictors of electrical storm (ES), including chronic total occlusion in an infarct-related coronary artery (infarct-related artery CTO, IRACTO), in a cohort of patients with prior myocardial infarction (MI) and implantable cardioverter-defibrillators (ICD)., Methods: Multicenter observational cohort study including 643 consecutive patients with prior MI and a first ICD implanted between 2005 and 2018 at three tertiary hospitals. All the patients included in the study had undergone a diagnostic coronary angiography before ICD implantation. The variable prior ventricular arrhythmias (VA+) was positive in patients with secondary prevention ICDs and in those with at least one appropriate ICD therapy after primary prevention implantation., Results: During a median follow-up of 42 months 59 patients (9%) suffered ES. The presence of at least one IRACTO not revascularized (IRACTO-NR) was associated with a significantly higher cumulative incidence of ES (14.5% vs 4.8%, p < 0.001). IRACTO-NR maintained a significant association with ES after adjustment for potential confounders (HR 2.3, p = 0.005) and was an independent predictor of ES together with VA+ and LVEF. The best cut-off of LVEF to predict ES was ≤38%. A risk-prediction model based on IRACTO-NR, VA+ and LVEF≤38% identified three categories of ES risk (low, intermediate and high), with progressively increasing cumulative incidence of ES (2.2%, 9% and 20%)., Conclusion: In a cohort of patients with prior MI and ICD, IRACTO-NR is an independent predictor of ES. A new risk-prediction model allowed the identification of three categories of risk, with potentially important clinical implications., (Copyright © 2022 Elsevier B.V. All rights reserved.)

Published
2022
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39. Predictors of acute inefficacy and the radiofrequency energy time required for cavotricuspid isthmus-dependent atrial flutter ablation.

Author

Pérez-Rodon J, Rodriguez-García J, Sarrias-Merce A, Rivas-Gandara N, Roca-Luque I, Francisco-Pascual J, Santos-Ortega A, Martín-Sánchez G, Ferreira-González I, Rodríguez-Palomares J, Evangelista-Masip A, García-Dorado D, and Moya-Mitjans À

Subjects
Age Distribution, Atrial Flutter diagnosis, Comorbidity, Energy Transfer, Female, Humans, Male, Middle Aged, Prevalence, Prognosis, Retrospective Studies, Risk Factors, Sex Distribution, Spain epidemiology, Treatment Failure, Treatment Outcome, Tricuspid Valve Insufficiency diagnosis, Atrial Flutter epidemiology, Atrial Flutter surgery, Catheter Ablation statistics & numerical data, Heart Atria surgery, Heart Conduction System surgery, Tricuspid Valve Insufficiency epidemiology
Abstract

Purpose: Although cavotricuspid isthmus-dependent atrial flutter (CTI-AFL) ablation is a highly efficacious treatment, a bidirectional CTI block cannot be achieved in some patients. In this study, we sought to determine the predictors of acute inefficacy of CTI-AFL ablation and the predictors of the radiofrequency (RF) energy time required to achieve a complete bidirectional CTI block., Methods: All consecutive patients who underwent stand-alone CTI-AFL ablation in our institution, except patients with congenital heart disease, were included in this retrospective study. Clinical, echocardiographic, and ablation data were collected from the Arrhythmia Unit and Imaging Unit databases and medical charts., Results: Three hundred and fifty-five patients, with a mean age 63 ± 12 years, were included. The ablation was acutely inefficacious in 30 patients (9%). Tricuspid regurgitation was the only independent predictor of acute inefficacy of CTI-AFL ablation (OR 3.161, 95% CI 1.084-9.220, p = 0.035) and was associated with a longer RF time required to achieve CTI bidirectional block (p = 0.031). Age was inversely correlated with the RF time required to achieve a bidirectional CTI block (r = -0.133, p = 0.025). A previous CTI RF ablation, chronic obstructive pulmonary disease (COPD), the use of an irrigated catheter, and advanced age were the independent predictors for requiring less RF energy time to achieve a bidirectional CTI block., Conclusions: Tricuspid regurgitation is associated with less acute efficacy in CTI-AFL ablation. Prior CTI ablation, COPD, use of an irrigated catheter, and advanced age are independent predictors for needing less RF energy time to achieve a complete bidirectional CTI block.

Published
2017
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40. Episodes of thyrotoxicosis in Hashimoto's thyroiditis.

Author

Gonzalez Gonzalez A, Recio Cordov JM, Rodriguez-García JL, Velasco Romero AM, and Rubio Herrera MA

Subjects
Adult, Antithyroid Agents therapeutic use, Biomarkers blood, Female, Hashimoto Disease blood, Hashimoto Disease drug therapy, Humans, Methimazole therapeutic use, Thyroid Function Tests, Thyrotropin blood, Thyroxine blood, Treatment Outcome, Hashimoto Disease complications, Hashimoto Disease diagnosis, Thyrotoxicosis diagnosis, Thyrotoxicosis etiology
Published
2010

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