44 results on '"Rodriguez-Adrada, Esther"'
Search Results
2. Effect of Flu Vaccination on Severity and Outcome of Heart Failure Decompensations
- Author
-
Miró, ÒSCAR, IVARS, NICOLE, LOPEZ-AYALA, PEDRO, GIL, VÍCTOR, LLAUGER, LLUÍS, ALQUÉZAR-ARBÉ, AITOR, JACOB, JAVIER, RODRÍGUEZ-ADRADA, ESTHER, TOST, JOSEP, MIR, MARÍA, GIL, CRISTINA, SÁNCHEZ, SUSANA, AGUIRRE, ALFONS, MARTÍN, ENRIQUE, ALONSO, M. ISABEL, GARRIDO, JOSÉ MANUEL, LÓPEZ-GRIMA, M. LUISA, LUCAS-IMBERNON, FRANCISCO JAVIER, SÁNCHEZ, CAROLINA, ESCODA, ROSA, GIL, ADRIANA, ESPINOSA, BEGOÑA, WUSSLER, DESIREE, PEACOCK, W. FRANK, MUELLER, CHRISTIAN, and LLORENS, PERE
- Published
- 2023
- Full Text
- View/download PDF
3. Analysis of standards of quality for outcomes in acute heart failure patients directly discharged home from emergency departments and their relationship with the emergency department direct discharge rate
- Author
-
Fuentes, Marta, Gil, Cristina, Alonso, Héctor, Pérez-Llantada, Enrique, Martín-Sánchez, Francisco Javier, García, Guillermo Llopis, Cadenas, Mar Suárez, Miró, Òscar, Gil, Víctor, Escoda, Rosa, Aguiló, Sira, Sánchez, Carolina, Pérez-Durá, María José, Salvo, Eva, Pavón, José, Noval, Antonio, Manuel Torres, José, López-Grima, María Luisa, Valero, Amparo, Juan, María Ángeles, Aguirre, Alfons, Pedragosa, Maria Angels, Masó, Silvia Mínguez, Alonso, María Isabel, Ruiz, Francisco, Miguel Franco, José, Mecina, Ana Belén, Tost, Josep, Berenguer, Marta, Donea, Ruxandra, Ramón, Susana Sánchez, Rodríguez, Virginia Carbajosa, Piñera, Pascual, Andrés Sánchez Nicolás, José, Garate, Raquel Torres, Alquézar-Arbé, Aitor, Rizzi, Miguel Alberto, Herrera, Sergio, Jacob, Javier, Roset, Alex, Cabello, Irene, Haro, Antonio, Richard, Fernando, María Álvarez Pérez, José, Diez, María Pilar López, Puente, Pablo Herrero, Álvarez, Joaquín Vázquez, García, Belén Prieto, García, María García, González, Marta Sánchez, Llorens, Pere, Javaloyes, Patricia, Marquina, Víctor, Jiménez, Inmaculada, Hernández, Néstor, Brouzet, Benjamín, Espinosa, Begoña, Gil, Adriana, Andueza, Juan Antonio, Romero, Rodolfo, Ruíz, Martín, Calvache, Roberto, Serralta, María Teresa Lorca, Jave, Luis Ernesto Calderón, Arriaga, Beatriz Amores, Bergua, Beatriz Sierra, Mojarro, Enrique Martín, Jiménez, Brigitte Silvana Alarcón, Bécquer, Lisette Travería, Burillo, Guillermo, García, Lluís Llauger, LaSalle, Gerard Corominas, Urbano, Carmen Agüera, Soto, Ana Belén García, Padial, Elisa Delgado, Ferrer, Ester Soy, Múñoz, María Adroher, Manuel Garrido, José, Lucas-Imbernón, Francisco Javier, Gaya, Rut, Bibiano, Carlos, Mir, María, Rodríguez, Beatriz, Luis Carballo, José, Rodríguez-Adrada, Esther, Miranda, Belén Rodríguez, Martín, Monika Vicente, Casanova, Pere Coma, Alvarós, Joan Espinach, López-Díez, María Pilar, Rossello, Xavier, Herrero, Pablo, Alquézar, Aitor, Garrido, José Manuel, Lucas-Invernón, Francisco Javier, Torres-Murillo, José, Raquel-Torres-Gárate, Mecina, Ana B., Traveria, Lissette, Agüera, Carmen, Takagi, Koji, Möckel, Martin, Pang, Peter S., Collins, Sean P., and Mueller, Christian E.
- Published
- 2021
- Full Text
- View/download PDF
4. Influence of the length of hospitalisation in post-discharge outcomes in patients with acute heart failure: Results of the LOHRCA study
- Author
-
Miró, Òscar, Padrosa, Joan, Takagi, Koji, Gayat, Étienne, Gil, Víctor, Llorens, Pere, Martín-Sánchez, Francisco Javier, Herrero-Puente, Pablo, Jacob, Javier, Montero, María Mir, Tost, Josep, Díez, María Pilar López, Traveria, Lissete, Torres-Gárate, Raquel, Alonso, María Isabel, Agüera, Carmen, Valero, Amparo, Javaloyes, Patricia, Peacock, W. Frank, Bueno, Héctor, Mebazaa, Alexandre, Fuentes, Marta, Gil, Cristina, Alonso, Héctor, Garmila, Pablo, García, Guillermo Llopis, Yáñez-Palma, María Cecilia, López, Sergio Iglesias, Escoda, Rosa, Xipell, Carolina, Sánchez, Carolina, Gaytan, Josep María, Pérez-Durá, María José, Salvo, Eva, Pavón, José, Noval, Antonio, Torres, José Manuel, López-Grima, María Luisa, Juan, Marian Ángeles, Aguirre, Alfons, Morales, Julián Errasti, Masó, Silvia Mínguez, Ruiz, Francisco, Franco, José Miguel, Mecina, Ana Belén, Sánchez, Susana, Carbajosa, Virginia, Piñera, Pascual, Nicolás, José Andrés Sánchez, Garate, Raquel Torres, Alquezar, Aitor, Rizzi, Miguel Alberto, Herrera, Sergio, Roset, Alex, Cabello, Irene, Richard, Fernando, Pérez, José María Álvarez, Diez, María Pilar López, Álvarez, Joaquín Vázquez, García, Belén Prieto, Sánchez González, María García García yMarta, Marquina, Víctor, Jiménez, Inmaculada, Hernández, Néstor, Brouzet, Benjamín, Ramos, Sergio, López, Ana, Andueza, Juan Antonio, Romero, Rodolfo, Ruíz, Martín, Calvache, Roberto, Lorca, María Teresa, Calderón, Luis, Arriaga, Beatriz Amores, Sierra, Beatriz, Mojarro, Enrique Martín, Bécquer, Lisette Travería, Burillo, Guillermo, García, Lluís Llauger, LaSalle, Gerard Corominas, Urbano, Carmen Agüera, Soto, Ana Belén García, Padial, Elisa Delgado, Ferrer, Ester Soy, Garrido, Manuel, Lucas, Francisco Javier, Gaya, Rut, Bibiano, Carlos, Mir, María, Rodríguez, Beatriz, Sánchez, Natalia, Carballo, José Luis, Rodríguez-Adrada, Esther, and Rodríguez, Belén
- Published
- 2019
- Full Text
- View/download PDF
5. Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
- Author
-
Gil, Cristina, Alonso, Héctor, Pérez-Llantada, Enrique, Llopis-García, Guillermo, Santos-Matallana, Maria Carmen, Barrenechea-Moxó, María Luisa Docavo, Salgado-Pérez, Lucía, Escoda, Rosa, Xipell, Carolina, Sánchez, Carolina, Gaytan, Josep María, Pérez-Durá, María José, Salvo, Eva, Pavón, José, Noval, Antonio, Torres, José Manuel, López-Grima, María Luisa, Valero, Amparo, Juan, María Ángeles, Aguirre, Alfons, Pedragosa, Maria Angels, Mínguez-Masó, Silvia, Alonso, María Isabel, Ruiz, Francisco, Franco, José Miguel, Mecina, Ana Belén, Tost, Josep, Berenguer, Marta, Donea, Ruxandra, Sánchez-Ramón, Susana, Carbajosa-Rodríguez, Virginia, Piñera, Pascual, Sánchez-Nicolás, José Andrés, Garate, Raquel Torres, Alquézar-Arbé, Aitor, Rizzi, Miguel Alberto, Herrera, Sergio, Roset, Alex, Cabello, Irene, Haro, Antonio, Richard, Fernando, Álvarez-Perez, José María, López-Diez, María Pilar, Vázquez-Álvarez, Joaquín, Prieto-García, Belén, García, María García, González, Marta Sánchez, Javaloyes, Patricia, Marquina, Víctor, Jiménez, Inmaculada, Hernández, Néstor, Brouzet, Benjamín, Espinosa, Begoña, Andueza, Juan Antonio, Romero, Rodolfo, Ruíz, Martín, Calvache, Roberto, Serralta, María Teresa Lorca, Jave, Luis Ernesto Calderón, Arriaga, Beatriz Amores, Bergua, Beatriz Sierra, Mojarro, Enrique Martín, Jiménez, Brigitte Silvana Alarcón, Bécquer, Lisette Travería, Burillo, Guillermo, García, Lluís Llauger, LaSalle, Gerard Corominas, Urbano, Carmen Agüera, Soto, Ana Belén García, Padial, Elisa Delgado, Ferrer, Ester Soy, Garrido, José Manuel, Lucas-Imbernón, Francisco Javier, Gaya, Rut, Bibiano, Carlos, Mir, María, Rodríguez, Beatriz, Carballo, José Luis, Rodríguez-Adrada, Esther, Miranda, Belén Rodríguez, Jacob, Javier, Llauger, Lluis, Herrero-Puente, Pablo, Martín-Sánchez, Francisco Javier, Llorens, Pere, Gil, Victor, Fuentes, Marta, and Miró, Òscar
- Published
- 2019
- Full Text
- View/download PDF
6. Effect of risk of malnutrition on 30-day mortality among older patients with acute heart failure in Emergency Departments
- Author
-
Martín-Sánchez, Francisco Javier, Cuesta Triana, Federico, Rossello, Xavier, Pardo García, Rebeca, Llopis García, Guillermo, Caimari, Francisca, Vidán, María Teresa, Ruiz Artacho, Pedro, González del Castillo, Juan, Llorens, Pere, Herrero, Pablo, Jacob, Javier, Gil, Víctor, Fernández Pérez, Cristina, Gil, Pedro, Bueno, Héctor, Miró, Òscar, Matía Martín, Pilar, Rodríguez Adrada, Esther, Santos, María Carmen, Salgado, Lucía, Brizzi, Berenice Nayla, Docavo, María Luisa, del Mar Suárez-Cadenas, María, Xipell, Carolina, Sánchez, Carolina, Aguiló, Sira, Gaytan, Josep María, Jerez, Alba, Pérez-Durá, María José, Berrocal Gil, Pablo, López-Grima, María Luisa, Valero, Amparo, Aguirre, Alfons, Pedragosa, Maria Àngels, Piñera, Pascual, LázaroAragues, Paula, Sánchez Nicolás, José Andrés, Rizzi, Miguel Alberto, Herrera Mateo, Sergio, Alquezar, Aitor, Roset, Alex, Ferrer, Carles, Llopis, Ferrán, Álvarez Pérez, José María, López Diez, María Pilar, Richard, Fernando, Fernández-Cañadas, José María, Carratalá, José Manuel, Javaloyes, Patricia, Andueza, Juan Antonio, Sevillano Fernández, José Antonio, Romero, Rodolfo, Merlo Loranca, Marta, Álvarez Rodríguez, Virginia, Lorca, María Teresa, Calderón, Luis, Soy Ferrer, Ester, Manuel Garrido, José, and Martín Mojarro, Enrique
- Published
- 2019
- Full Text
- View/download PDF
7. Effect of Barthel Index on the Risk of Thirty-Day Mortality in Patients With Acute Heart Failure Attending the Emergency Department: A Cohort Study of Nine Thousand Ninety-Eight Patients From the Epidemiology of Acute Heart Failure in Emergency Departments Registry
- Author
-
Fuentes, Marta, Gil, Cristina, Alonso, Héctor, Garmila, Pablo, Rodríguez Adrada, Esther, Llopis García, Guillermo, Yáñez-Palma, M. Cecilia, López, Sergio Iglesias, Escoda, Rosa, Xipell, Carolina, Sánchez, Carolina, Gaytan, Josep M<ce:sup loc='post">a</ce:sup>, Pérez-Durá, María José, Salvo, Eva, Pavón, José, Noval, Antonio, Torres, José M., López-Grima, María Luisa, Valero, Amparo, Juan, Marian Ángeles, Aguirre, Alfons, Morales, Julián Errasti, Mínguez Masó, Silvia, Isabel Alonso, María, Ruiz, Francisco, Miguel Franco, José, Díaz, Elena, Belén Mecina, Ana, Tost, Josep, Sánchez, Susana, Carbajosa, Virginia, Piñera, Pascual, Sánchez Nicolás, José Andrés, Torres Garate, Raquel, Alquezar, Aitor, Alberto Rizzi, Miguel, Herrera, Sergio, Roset, Alex, Cabello, Irene, Richard, Fernando, Álvarez Pérez, José María, Pilar López Diez, María, Vázquez Álvarez, Joaquín, Alonso Morilla, Ana, Irimia, Andrea, Javaloyes, Patricia, Marquina, Víctor, Jiménez, Inmaculada, Hernández, Néstor, Brouzet, Benjamín, Ramos, Sergio, López, Ana, Antonio Andueza, Juan, Antonio Sevillano, José, Romero, Rodolfo, Calvache, Roberto, Lorca, María Teresa, Calderón, Luis, Amores Arriaga, Beatriz, Sierra, Beatriz, Martín Mojarro, Enrique, Travería Bécquer, Lisette, Burillo, Guillermo, Llauger García, Lluís, Corominas LaSalle, Gerard, Agüera Urbano, Carmen, Belén García, Ana, Elisa Delgado Padial, Soto, Soy Ferrer, Ester, Garrido, Manuel, Javier Lucas, Francisco, Gaya, Rut, Rossello, Xavier, Miró, Òscar, Llorens, Pere, Jacob, Javier, Herrero-Puente, Pablo, Gil, Víctor, Rizzi, Miguel A., Pérez-Durá, María J., Espiga, Fernando R., Sevillano, José A., Vidán, María T., Bueno, Héctor, Pocock, Stuart J., and Martín-Sánchez, Francisco J.
- Published
- 2019
- Full Text
- View/download PDF
8. Adherence to Mediterranean Diet and All-Cause Mortality After an Episode of Acute Heart Failure: Results of the MEDIT-AHF Study
- Author
-
Alonso, Héctor, Fuentes, Marta, Gil, Cristina, Pérez-Durá, María José, Salvo, Eva, Escoda, Rosa, Xipell, Carolina, Sánchez, Carolina, Gaytan, Josep M., Noval, Antonio, Torres, José M., López-Grima, Maria Luisa, Juan, Maria Angeles, Valero, Amparo, Pedragosa, Maria Àngels, Alonso, Maria Isabel, Ruiz, Francisco, Romero, Rodolfo, Calvache, Roberto, Morante, Carlos, Lorca, Maria Teresa, Mecina, Ana Belen, Tost, Josep, de la Fuente Penco, Belén, López Sánchez, Antònia, Sánchez, Susana, Piñera, Pascual, Garate, Raquel Torres, Alquézar, Aitor, Rizzi, Miguel Alberto, Richard, Fernando, Álvarez Pérez, José María, López Diez, Maria Pilar, Lucas, Javier, Roset, Álex, Rodríguez-Adrada, Esther, Llopis García, Guillermo, Garrido, José Manuel, Fernández-Cañadas, José Maria, Marquina, Víctor, Jiménez, Inmaculada, Javaloyes, Patricia, Vázquez Alvarez, Joaquin, Alonso Morilla, Ana, Irimia, Andrea, Miró, Òscar, Estruch, Ramon, Martín-Sánchez, Francisco J., Gil, Víctor, Jacob, Javier, Herrero-Puente, Pablo, Herrera Mateo, Sergio, Aguirre, Alfons, Andueza, Juan A., and Llorens, Pere
- Published
- 2018
- Full Text
- View/download PDF
9. External validation of the myocardial-ischaemic-injury-index machine learning algorithm for the early diagnosis of myocardial infarction: a multicentre cohort study
- Author
-
Lopez-Ayala, Pedro, Boeddinghaus, Jasper, Nestelberger, Thomas, Koechlin, Luca, Zimmermann, Tobias, Bima, Paolo, Glaeser, Jonas, Spagnuolo, Carlos C, Champetier, Arnaud, Miro, Oscar, Martin-Sanchez, Francisco Javier, Keller, Dagmar I, Christ, Michael, Wildi, Karin, Breidthardt, Tobias, Strebel, Ivo, Mueller, Christian, Reichlin, Tobias, Kaeslin, Marina, Potlukova, Eliska, Kawecki, Damian, Geigy, Nicolas, Rentsch, Katharina, Shrestha, Samyut, Guzman-Tacla, Caroline A., Herraiz-Recuenco, Lourdes, Morawiec, Beata, Munzk, Piotr, Freese, Michael, Martinez-Nadal, Gemma, Fuenzalida, Carolina, Calderon, Sofia, Rodriguez Adrada, Esther, Ganovská, Eva, Parenica, Jiri, von Eckardstein, Arnold, Campodarve, Isabel, and Gea, Joachim
- Abstract
The myocardial-ischaemic-injury-index (MI3) is a novel machine learning algorithm for the early diagnosis of type 1 non-ST-segment elevation myocardial infarction (NSTEMI). The performance of MI3, both when using early serial blood draws (eg, at 1 h or 2 h) and in direct comparison with guideline-recommended algorithms, remains unknown. Our aim was to externally validate MI3and compare its performance with that of the European Society of Cardiology (ESC) 0/1h-algorithm.
- Published
- 2024
- Full Text
- View/download PDF
10. Morphine Use in the ED and Outcomes of Patients With Acute Heart Failure: A Propensity Score-Matching Analysis Based on the EAHFE Registry
- Author
-
Fuentes, Marta, Gil, Cristina, Pérez-durá, María José, Salvo, Eva, Vallés, José, Escoda, Rosa, Xipell, Carolina, Sánchez, Carolina, Pavón, José, Álvarez, Ana Bella, Noval, Antonio, Torres, José M., López-Grima, Maria Luisa, Valero, Amparo, Aguirre, Alfons, Pedragosa, Maria Àngels, Alonso, Maria Isabel, Sancho, Helena, Ruiz, Paco, Giménez, Antonio, Miguel Franco, José, Pardo, Sergio, Mecina, Ana Belen, Tost, Josep, Fabregat, Jordi, Sánchez, Susana, Piñera, Pascual, Garate, Raquel Torres, Alquezar, Aitor, Rizzi, Miguel Alberto, Richard, Fernando, Lucas, Javier, Cabello, Irene, Roset, Álex, Rodríguez-Adrada, Esther, García, Guillermo Llopis, Garrido, José Manuel, Miró, Òscar, Gil, Víctor, Martín-Sánchez, Francisco J., Herrero-Puente, Pablo, Jacob, Javier, Mebazaa, Alexandre, Harjola, Veli-Pekka, Ríos, José, Hollander, Judd E., Peacock, W. Frank, and Llorens, Pere
- Published
- 2017
- Full Text
- View/download PDF
11. Impact of Frailty and Disability on 30-Day Mortality in Older Patients With Acute Heart Failure
- Author
-
Pérez-Durá, María José, Gil, Pablo Berrocal, Miró, Óscar, Espinosa, Víctor Gil, Sánchez, Carolina, Aguiló, Sira, Vall, Maria Àngels Pedragosa, Aguirre, Alfons, Piñera, Pascual, Aragues, Paula Lázaro, Bordigoni, Miguel Alberto Rizzi, Alquezar, Aitor, Richard, Fernando, Jacob, Javier, Ferrer, Carles, Llopis, Ferrán, Sánchez, F. Javier Martín, del Castillo, Juan González, Rodríguez-Adrada, Esther, García, Guillermo Llopis, Salgado, Lucía, Mandly, Eduardo Anguita, Ortega, Julián Sanz, de los Ángeles Cuadrado Cenzual, María, de Heredia, Maria Dolores Inés Ortega, Soriano, Pere Llorens, Fernández-Cañadas, José María, Carratalá, José Manuel, Javaloyes, Patricia, Puente, Pablo Herrero, García, Iván Rancaño, Coya, María Fernández, Fernández, José Antonio Sevillano, Andueza, Juan, Pareja, Rodofo Romero, del Arco, Carmen, Martín, Alfonso, Torres, Raquel, Miranda, Belén Rodríguez, Martín, Vanesa Sendín, Guillén, Carlos Bibiano, Puig, Rodrigo Pacheco, Martín-Sánchez, Francisco Javier, Vidan, Maria Teresa, Llopis García, Guillermo, González del Castillo, Juan, Rizzi, Miguel Alberto, Lázaro Aragues, Paula, Llorens, Pere, Herrero, Pablo, Gil, Víctor, Fernández, Cristina, Bueno, Héctor, and Miró, Òscar
- Published
- 2017
- Full Text
- View/download PDF
12. Mensajes clave para la atención inicial del anciano con insuficiencia cardiaca aguda
- Author
-
Martín-Sánchez, F. Javier, Rodríguez-Adrada, Esther, Llorens, Pere, and Formiga, Francesc
- Published
- 2015
- Full Text
- View/download PDF
13. Early diagnosis of acute myocardial infarction in patients with mild elevations of cardiac troponin
- Author
-
Boeddinghaus, Jasper, Reichlin, Tobias, Nestelberger, Thomas, Twerenbold, Raphael, Meili, Yvette, Wildi, Karin, Hillinger, Petra, Giménez, Maria Rubini, Cupa, Janosch, Schumacher, Lukas, Schubera, Marie, Badertscher, Patrick, Corbière, Sydney, Grimm, Karin, Puelacher, Christian, Sabti, Zaid, Widmer, Dayana Flores, Schaerli, Nicolas, Kozhuharov, Nikola, Shrestha, Samyut, Bürge, Tobias, Mächler, Patrick, Büchi, Michael, Rentsch, Katharina, Miró, Òscar, López, Beatriz, Martin-Sanchez, F. Javier, Rodriguez-Adrada, Esther, Morawiec, Beata, Kawecki, Damian, Ganovská, Eva, Parenica, Jiri, Lohrmann, Jens, Buser, Andreas, Keller, Dagmar I., Osswald, Stefan, and Mueller, Christian
- Published
- 2017
- Full Text
- View/download PDF
14. Direct Comparison of the 0/1h and 0/3h Algorithms for Early Rule-Out of Acute Myocardial Infarction
- Author
-
Badertscher, Patrick, Boeddinghaus, Jasper, Twerenbold, Raphael, Nestelberger, Thomas, Wildi, Karin, Wussler, Desiree, Schwarz, Jonas, Puelacher, Christian, Rubini Giménez, Maria, Kozhuharov, Nikola, du Fay de Lavallaz, Jeanne, Cerminara, Sara Elisa, Potlukova, Eliska, Rentsch, Katharina, Miró, Òscar, López, Beatriz, Martin-Sanchez, F. Javier, Morawiec, Beata, Muzyk, Piotr, Keller, Dagmar I., Reichlin, Tobias, Mueller, Christian, Sabti, Zaid, Strebel, Ivo, Shrestha, Samyut, Flores, Dayana, Freese, Michael, Stelzig, Claudia, Kulangara, Caroline, Meissner, Kathrin, Schaerli, Nicolas, Mueller, Deborah, Yufera Sanchez, Ana, Sazgary, Lorraine, Marbot, Stella, Fuenzalida, Carolina, Calderón, Sofia, Rodriguez Adrada, Esther, Kawecki, Damian, Nowalany-Kozielska, Ewa, Parenica, Jiri, Ganovská, Eva, von Eckardstein, Arnold, Lohrmann, Jens, Kloos, Wanda, Osswald, Stefan, Buser, Andreas, Bingisser, Roland, and Geigy, Nicolas
- Published
- 2018
- Full Text
- View/download PDF
15. Management of Acute Heart Failure in Spanish Emergency Departments Based on Age
- Author
-
Martín-Sánchez, Francisco Javier, Marino-Genicio, Rocío, Rodríguez-Adrada, Esther, Jacob, Javier, Herrero, Pablo, Miró, Òscar, Llorens, Pere, and Ribera-Casado, José Manuel
- Published
- 2013
- Full Text
- View/download PDF
16. El manejo de la insuficiencia cardiaca aguda en los servicios de urgencias hospitalarios españoles en función de la edad
- Author
-
Martín-Sánchez, Francisco Javier, Marino-Genicio, Rocío, Rodríguez-Adrada, Esther, Jacob, Javier, Herrero, Pablo, Miró, Òscar, Llorens, Pere, and Ribera-Casado, José Manuel
- Published
- 2013
- Full Text
- View/download PDF
17. Direct Comparison of 4 Very Early Rule-Out Strategies for Acute Myocardial Infarction Using High-Sensitivity Cardiac Troponin I
- Author
-
Boeddinghaus, Jasper, Nestelberger, Thomas, Twerenbold, Raphael, Wildi, Karin, Badertscher, Patrick, Cupa, Janosch, Bürge, Tobias, Mächler, Patrick, Corbière, Sydney, Grimm, Karin, Giménez, Maria Rubini, Puelacher, Christian, Shrestha, Samyut, Flores Widmer, Dayana, Fuhrmann, Jakob, Hillinger, Petra, Sabti, Zaid, Honegger, Ursina, Schaerli, Nicolas, Kozhuharov, Nikola, Rentsch, Katharina, Miró, Òscar, López, Beatriz, Martin-Sanchez, F. Javier, Rodriguez-Adrada, Esther, Morawiec, Beata, Kawecki, Damian, Ganovská, Eva, Parenica, Jiri, Lohrmann, Jens, Kloos, Wanda, Buser, Andreas, Geigy, Nicolas, Keller, Dagmar I., Osswald, Stefan, Reichlin, Tobias, and Mueller, Christian
- Published
- 2017
- Full Text
- View/download PDF
18. Sensitivity of the SNNOOP10 list in the high-risk secondary headache detection
- Author
-
García-Azorín, David, primary, Abelaira-Freire, Jaime, additional, González-García, Nuria, additional, Rodriguez-Adrada, Esther, additional, Schytz, Henrik Winther, additional, Barloese, Mads, additional, Guerrero, Ángel Luis, additional, Porta-Etessam, Jesús, additional, and Martín-Sánchez, Francisco Javier, additional
- Published
- 2022
- Full Text
- View/download PDF
19. Sensitivity of the SNNOOP10 list in the high-risk secondary headache detection
- Author
-
García-Azorín, David, Abelaira-Freire, Jaime, González-García, Nuria, Rodriguez-Adrada, Esther, Schytz, Henrik Winther, Barloese, Mads, Guerrero, Ángel Luis, Porta-Etessam, Jesús, Martín-Sánchez, Francisco Javier, García-Azorín, David, Abelaira-Freire, Jaime, González-García, Nuria, Rodriguez-Adrada, Esther, Schytz, Henrik Winther, Barloese, Mads, Guerrero, Ángel Luis, Porta-Etessam, Jesús, and Martín-Sánchez, Francisco Javier
- Abstract
Aim: To evaluate the diagnostic accuracy of the SNNOOP10 list in the detection of high-risk headaches. Methods: Patients that visited the Hospital Clínico San Carlos (Madrid) emergency department due to headache that were allocated to a Manchester Triage System level between critical and urgent were prospectively included but retrospectively analysed. A researcher blind to the patients’ diagnosis administered a standardised questionnaire and afterwards a neurologist blind to the questionnaire results diagnosed the patient according to the International Classification of Headache Disorders. The primary endpoint was to assess the sensitivity of the SNNOOP10 list in the detection of high-risk headaches. Secondary endpoints included the evaluation of the sensitivity, specificity, positive predictive value, negative predictive value and area under the curve of each SNNOOP10 item. Results: Between April 2015 and October 2021, 100 patients were included. Patients were 44 years old (inter-quartile range: 33.6–64.7) and 57% were female. We identified 37 different diagnoses. Final diagnosis was a primary headache in 33%, secondary headache in 65% and cranial neuralgia in 2%. There were 46 patients that were considered as having high-risk headache. Patients from the primary headache group were younger and more frequently female. Sensitivity of SNNOOP10 list was 100% (95% confidence interval: 90.2%–100%). The items with higher sensitivity were neurologic deficit or disfunction (75.5%), pattern change or recent onset of the headache (64.4%), onset after 50 years (64.4%). The most specific items were posttraumatic onset of headache (94.5%), neoplasm in history (89.1%) and systemic symptoms (89%). The area under the curve of the SNNOOP10 list was 0.66 (95% CI: 0.55–0.76). Conclusion: The red flags from the SNNOOP10 list showed a 100% sensitivity in the detection of high-risk headache disorders.
- Published
- 2022
20. sj-pdf-1-cep-10.1177_03331024221120249 - Supplemental material for Sensitivity of the SNNOOP10 list in the high-risk secondary headache detection
- Author
-
García-Azorín, David, Abelaira-Freire, Jaime, González-García, Nuria, Rodriguez-Adrada, Esther, Schytz, Henrik Winther, Barloese, Mads, Guerrero, Ángel Luis, Porta-Etessam, Jesús, and Martín-Sánchez, Francisco Javier
- Subjects
FOS: Psychology ,FOS: Clinical medicine ,170199 Psychology not elsewhere classified ,110319 Psychiatry (incl. Psychotherapy) ,110306 Endocrinology ,111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified ,110904 Neurology and Neuromuscular Diseases ,Neuroscience - Abstract
Supplemental material, sj-pdf-1-cep-10.1177_03331024221120249 for Sensitivity of the SNNOOP10 list in the high-risk secondary headache detection by David García-Azorín, Jaime Abelaira-Freire, Nuria González-García, Esther Rodriguez-Adrada, Henrik Winther Schytz, Mads Barloese, Ángel Luis Guerrero, Jesús Porta-Etessam and Francisco Javier Martín-Sánchez in Cephalalgia
- Published
- 2022
- Full Text
- View/download PDF
21. Novel Criteria for the Observe-Zone of the ESC 0/1h-hs-cTnT Algorithm
- Author
-
Lopez-Ayala, Pedro, primary, Nestelberger, Thomas, additional, Boeddinghaus, Jasper, additional, Koechlin, Luca, additional, Ratmann, Paul David, additional, Strebel, Ivo, additional, Gehrke, Juliane, additional, Meier, Severin, additional, Walter, Joan, additional, Rubini Gimenez, Maria, additional, Mutschler, Eugenio, additional, Miró, Òscar, additional, López-Barbeito, Beatriz, additional, Martín-Sánchez, Francisco Javier, additional, Rodríguez-Adrada, Esther, additional, Keller, Dagmar I., additional, Newby, L. Kristin, additional, Twerenbold, Raphael, additional, Giannitsis, Evangelos, additional, Lindahl, Bertil, additional, Mueller, Christian, additional, Zimmermann, Tobias, additional, Schoepfer, Hadrien, additional, Coscia, Tania, additional, Troester, Valentina, additional, Reichlin, Tobias, additional, Kaeslin, Marina, additional, Christ, Michael, additional, Meier, Mario, additional, Badertscher, Patrick, additional, Puelacher, Christian, additional, du Fay de Lavallaz, Jeanne, additional, Potlukova, Eliska, additional, Kawecki, Damian, additional, Geigy, Nicolas, additional, Rentsch, Katharina, additional, Shrestha, Samyut, additional, Morawiec, Beata, additional, Munzk, Piotr, additional, Breidthardt, Tobias, additional, Freese, Michael, additional, Martinez-Nadal, Gemma, additional, Fuenzalida, Carolina, additional, Calderón, Sofia, additional, Rodriguez Adrada, Esther, additional, Ganovská, Eva, additional, Parenica, Jiri, additional, von Eckardstein, Arnold, additional, Campodarve, Isabel, additional, Gea, Joachim, additional, Mccord, James, additional, Nowak, Richard, additional, Body, Richard, additional, deFilippi, Christopher R., additional, Christenson, Robert H., additional, Panteghini, Mauro, additional, Plebani, Mario, additional, Verschuren, Franck, additional, French, John, additional, Weiser, Silvia, additional, and Jernberg, Tomas, additional
- Published
- 2021
- Full Text
- View/download PDF
22. Thirty-day outcomes in frail older patients discharged home from the emergency department with acute heart failure: effects of high-risk criteria identified by the DEED FRAIL-AHF trial
- Author
-
Martín Sánchez, Francisco Javier, Parra Esquivel, Patricia, Llopis Garcia, Guillermo, Gonzalez del Castillo, Juan, Rodriguez Adrada, Esther, Espinosa, Begoña, López Diez, Maria Pilar, Romero Pareja, Rodolfo, Rizzi Bordigoni, Miguel Alberto, Pérez-Durá, Maria José, Bibiano, Carlos, Ferrer, Carles, Aguiló, Sira, Martín Mojarro, Enrique, Aguirre Tejedo, Alfons, Piñera, Pascual, López-Picado, Amanda, Llorens, Pere, Jacob, Javier, Gil, Víctor, Herrero Puente, Pablo, Fernandez Pérez, Cristina, Gil, Pedro, Calvo, Elpidio, Rossello, Xavier, Bueno, Hector, Burillo Putze, Guillermo, and Miró i Andreu, Òscar
- Subjects
Aged, 80 and over ,Heart Failure ,Male ,Acute heart failure., Aged., Anciano., Emergency department., Fragilidad., Frail elderly., Insuficiencia cardiaca aguda., Servicio de urgencias ,Emergency department ,Frail Elderly ,Acute heart failure ,Heart failure ,Insuficiència cardíaca ,Frail elderly ,Persones grans ,Patient Discharge ,Serveis d'urgències hospitalàries ,Acute Disease ,Hospital emergency services ,Humans ,Female ,Older people ,Emergency Service, Hospital ,Aged - Abstract
To study the effect of high-risk criteria on 30-day outcomes in frail older patients with acute heart failure (AHF) discharged from an emergency department (ED) or an ED's observation and short-stay areas.Secondary analysis of discharge records in the Older AHF Key Data registry. We selected frail patients (aged70 years) discharged with AHF from EDs. Risk factors were categorized as modifiable or nonmodifiable. The outcomes were a composite endpoint for a cardiovascular event (revisits for AHF, hospitalization for AHF, or cardiovascular death) and the number of days alive out-of-hospital (DAOH) within 30 days of discharge.We included 380 patients with a mean (SD) age of 86 (5.5) years (61.2% women). Modifiable risk factors were identified in 65.1%, nonmodifiable ones in 47.8%, and both types in 81.6%. The 30-day cardiovascular composite endpoint occurred in 83 patients (21.8%). The mean 30-day DAOH observed was 27.6 (6.1) days. Highrisk factors were present more often in patients who developed the cardiovascular event composite endpoint: the rates for patients with modifiable, nonmodifiable, or both types of risk were, respectively, as follows in comparison with patients not at high risk: 25.0% vs 17.2%, P = .092; 27.6% vs 16.7%, P = .010; and 24.7% vs 15.2%, P = .098). The 30-day DAOH outcome was also lower for at-risk patients, according to type of risk factor present: modifiable, 26.9 (7.0) vs 28.4 (4.4) days, P = .011; nonmodifiable, 27.1 (7.0) vs 28.0 (5.0) days, P = .127; and both, 27.1 (6.7) vs 28.8 (3.4) days, P = .005). After multivariate analysis, modifiable risk remained independently associated with fewer days alive (adjusted absolute difference in 30-day DAOH, -1.3 days (95% CI, -2.7 to -0.1 days). Nonmodifiable factors were associated with increased risk for the 30-day cardiovascular composite endpoint (adjusted absolute difference, 10.4%; 95% CI, -2.1% to 18.7%).Risk factors are common in frail elderly patients with AHF discharged home from hospital ED areas. Their presence is associated with a worse 30-day prognosis.Estudiar el efecto a 30 días de los criterios de alto riesgo (CAR) en los mayores frágiles con insuficiencia cardiaca aguda (ICA) dados de alta desde urgencias o unidades vinculadas (URG_UV).Análisis secundario del registro OAK-Discharge. Se seleccionaron pacientes frágiles 70 años con ICA dados de alta desde URG_UV. Los CAR se clasificaron en modificables (CAR_M) y no modificables (CAR_NM). Las variables de resultado fueron la compuesta cardiovascular (VC_CV) (revisita u hospitalización por ICA o mortalidad cardiovascular) y días vivos fuera del hospital (DVFH) a 30 días del alta.Se incluyeron 380 pacientes con una edad media de 86 (DE 5,5) años, 61,2% mujeres. Un 65,1% tuvo CAR_M, 47,8% CAR_NM y 81,6% ambos. Ochenta y tres pacientes (21,8%) presentaron la VC_CV a 30 días. La media de DVFH a 30 días fue de 27,6 (DE 6,1) días. La presencia de CAR modificable, no modificable o ambos, se asoció más frecuentemente a la VC_CV a 30 días (25,0% vs 17,2%, p = 0,092; 27,6% vs 16,7%, p = 0,010; 24,7% vs 15,2%, p = 0,098) y a menos DVFH a 30 días [26,9 (7,0) vs 28,4 (4,4), p = 0,011; 27,1 (7,0) vs 28,0 (5,0), p = 0,127; 27,1 (6,7) vs 28,8 (3,4), p = 0,005], respectivamente. Tras el análisis multivariante, los CAR_M se asociaron de forma independiente con menos DVFH a 30 días (diferencia absoluta ajustada –1,3 días; IC 95% –2,7 a –0,1) y los CAR_NM con más eventos en la VC_CV a 30 días (diferencia absoluta ajustada 10,4%; IC 95% 2,1% a 18,7%).Los CAR son frecuentes en los mayores frágiles con ICA dados de alta desde URG_UV y su presencia se asocia a peores resultados a 30 días tras alta.
- Published
- 2021
23. Temporal distribution of emergency room visits in patients with migraine and other headaches
- Author
-
García-Azorín, David, Abelaira-Freire, Jaime, Rodriguez-Adrada, Esther, González-García, Nuria, Planchuelo-Gómez, Álvaro, Guerrero, Ángel L., Porta-Etessam, Jesús, and Martín-Sánchez, Francisco J
- Abstract
Background: Headache is a leading reason for presentation to the emergency department (ED) with migraine being the most frequently headache. To ensure the adequate staffing of healthcare providers during peak times of headache visits, we analyzed the temporal distribution of emergency department visits in patients presenting with headache and/or migraine. Research design and methods: The authors conducted an ecological study, including all consecutive visits to the ED for headache. Patients were classified according to the IHS Classification. We analyzed circadian, circaseptan and circannual patterns for number of visits, comparing migraine patients with other headache patients. Results: There were 2132 ED visits for headache, including primary headache in 1367 (64.1%) cases; migraine in 963 (45.2%); secondary headache in 404 (18.9%); and unspecified headache in 366 (17.1%). The circadian pattern showed peaks around 11:00–13:00 and 17:00–19:00, with visits during the night shift 45% less frequent (p < 0.001). The circaseptan pattern showed a peak on Monday-Tuesday and a low point on Sunday (p < 0.007). The circannual pattern peaked in March and decreased in June. Conclusions: ED visits for headache showed specific circadian, circaseptan and circannual variations. No differences were found in these patterns when comparing migraine patients to other headache patients.
- Published
- 2021
- Full Text
- View/download PDF
24. Novel Criteria for the Observe-Zone of the ESC 0/1 h-hs-cTnT Algorithm
- Author
-
Lopez-Ayala, Pedro, Nestelberger, Thomas, Boeddinghaus, Jasper, Koechlin, Luca, Ratmann, Paul David, Strebel, Ivo, Gehrke, Juliane, Meier, Severin, Walter, Joan, Rubini Gimenez, Maria, Mutschler, Eugenio, Miro, Oscar, Lopez-Barbeito, Beatriz, Martin-Sanchez, Francisco Javier, Rodriguez-Adrada, Esther, Keller, Dagmar I., Newby, L. Kristin, Twerenbold, Raphael, Giannitsis, Evangelos, Lindahl, Bertil, Mueller, Christian, Lopez-Ayala, Pedro, Nestelberger, Thomas, Boeddinghaus, Jasper, Koechlin, Luca, Ratmann, Paul David, Strebel, Ivo, Gehrke, Juliane, Meier, Severin, Walter, Joan, Rubini Gimenez, Maria, Mutschler, Eugenio, Miro, Oscar, Lopez-Barbeito, Beatriz, Martin-Sanchez, Francisco Javier, Rodriguez-Adrada, Esther, Keller, Dagmar I., Newby, L. Kristin, Twerenbold, Raphael, Giannitsis, Evangelos, Lindahl, Bertil, and Mueller, Christian
- Abstract
BACKGROUND: The non-ST-segment-elevation myocardial infarction (NSTEMI) guidelines of the European Society of Cardiology (ESC) recommend a 3h cardiac troponin determination in patients triaged to the observe-zone of the ESC 0/1h-algorithm; however, no specific cutoff for further triage is endorsed. Recently, a specific cutoff for 0/3h high-sensitivity cardiac troponin T (hs-cTnT) change (7 ng/L) was proposed, warranting external validation. METHODS: Patients presenting with acute chest discomfort to the emergency department were prospectively enrolled into an international multicenter diagnostic study. Final diagnoses were centrally adjudicated by 2 independent cardiologists applying the fourth universal definition of myocardial infarction, on the basis of complete cardiac workup, cardiac imaging, and serial hs-cTnT. Hs-cTnT concentrations were measured at presentation, after 1 hour, and after 3 hours. The objective was to externally validate the proposed cutoff, and if necessary, derive and internally as well as externally validate novel 0/3h-criteria for the observe-zone of the ESC 0/1h-hs-cTnT-algorithm in an independent multicenter cohort. RESULTS: Among 2076 eligible patients, application of the ESC 0/1h-hs-cTnT-algorithm triaged 1512 patients (72.8%) to either rule out or rule in NSTEMI, leaving 564 patients (27.2%) in the observe-zone (adjudicated NSTEMI prevalence, 120/564 patients, 21.3%). The suggested 0/3h-hs-cTnT-change of <7 ng/L triaged 517 patients (91.7%) toward rule-out, resulting in a sensitivity of 33.3% (95% CI, 25.5-42.2), missing 80 patients with NSTEMI, and >= 7 ng/L triaged 47 patients toward rule-in (8.3%), resulting in a specificity of 98.4% (95% CI, 96.8-99.2). Novel derived 0/3h-criteria for the observe-zone patients ruled out NSTEMI with a 3h hs-cTnT concentration <15 ng/L and a 0/3h-hs-cTnT absolute change <4 ng/L, triaging 138 patients (25%) toward rule-out, resulting in a sensitivity of 99.2% (95% CI, 96.0-99.9), missing 1
- Published
- 2021
- Full Text
- View/download PDF
25. External Validation of the No Objective Testing Rules in Acute Chest Pain
- Author
-
Ratmann, Paul David, primary, Boeddinghaus, Jasper, additional, Nestelberger, Thomas, additional, Lopez‐Ayala, Pedro, additional, Koechlin, Luca, additional, Wildi, Karin, additional, Miro, Oscar, additional, Martín‐Sánchez, F. Javier, additional, Christ, Michael, additional, Twerenbold, Raphael, additional, Rubini Gimenez, Maria, additional, Keller, Dagmar I., additional, Mueller, Christian, additional, Troester, Valentina, additional, Meier, Mario, additional, Puelacher, Christian, additional, du Fay de Lavallaz, Jeanne, additional, Potlukova, Eliska, additional, Badertscher, Patrick, additional, Arslani, Ketina, additional, Freese, Michael, additional, Michou, Eleni, additional, Flores, Dayana, additional, Lohrmann, Jens, additional, Rentsch, Katharina, additional, Reichlin, Tobias, additional, López, Beatriz, additional, Fuenzalida, Carolina, additional, Rodriguez Adrada, Esther, additional, Ganovská, Eva, additional, Parenica, Jiri, additional, von Eckardstein, Arnold, additional, Morawiec, Beata, additional, Kawecki, Damian, additional, Muzyk, Piotr, additional, Bürgler, Franz, additional, and Geigy, Nicolas, additional
- Published
- 2021
- Full Text
- View/download PDF
26. Temporal distribution of emergency room visits in patients with migraine and other headaches
- Author
-
García-Azorín, David, primary, Abelaira-Freire, Jaime, additional, Rodriguez-Adrada, Esther, additional, González-García, Nuria, additional, Planchuelo-Gómez, Álvaro, additional, Guerrero, Ángel L., additional, Porta-Etessam, Jesús, additional, and Martín-Sánchez, Francisco J, additional
- Published
- 2021
- Full Text
- View/download PDF
27. Association of Previous Myocardial Infarction and Time to Presentation With Suspected Acute Myocardial Infarction
- Author
-
Troester, Valentina, primary, Strebel, Ivo, additional, Nestelberger, Thomas, additional, Boeddinghaus, Jasper, additional, Rubini Gimenez, Maria, additional, Lopez‐Ayala, Pedro, additional, Koechlin, Luca, additional, Glarner, Noemi, additional, Prepoudis, Alexandra, additional, Miró, Òscar, additional, Martin‐Sanchez, F. Javier, additional, Kawecki, Damian, additional, Keller, Dagmar I., additional, Twerenbold, Raphael, additional, Mueller, Christian, additional, Walter, Joan, additional, Yufera Sanchez, Ana, additional, Puelacher, Christian, additional, du Fay de Lavallaz, Jeanne, additional, Shrestha, Samyut, additional, López, Beatriz, additional, Rodriguez Adrada, Esther, additional, Muzyk, Piotr, additional, Morawiec, Beata, additional, Lohrmann, Jens, additional, Christ, Michael, additional, Ratmann, Paul David, additional, Badertscher, Patrick, additional, Arslani, Ketina, additional, Zimmermann, Tobias, additional, Freese, Michael, additional, Wildi, Karin, additional, Wussler, Desiree, additional, Gualandro, Danielle M, additional, Frey, Simon, additional, and Geigy, Nicolas, additional
- Published
- 2021
- Full Text
- View/download PDF
28. Circadian, weekly, seasonal, and temperature-dependent patterns of syncope aetiology in patients at increased risk of cardiac syncope
- Author
-
du Fay de Lavallaz, Jeanne, Badertscher, Patrick, Nestelberger, Thomas, Flores, Dayana, Miró, Òscar, Salgado, Emilio, Geigy, Nicolas, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F Javier, Rodriguez-Adrada, Esther, Di Somma, Salvatore, Peacock, W Frank, Kawecki, Damian, Boeddinghaus, Jasper, Twerenbold, Raphael, Puelacher, Christian, Wussler, Desiree, Strebel, Ivo, Keller, Dagmar I, Poepping, Imke, Kühne, Michael, Reichlin, Tobias, Mueller, Christian, BASEL IX Investigators, University of Zurich, and Mueller, Christian
- Subjects
2737 Physiology (medical) ,540 Chemistry ,610 Medicine & health ,2705 Cardiology and Cardiovascular Medicine ,10038 Institute of Clinical Chemistry - Published
- 2019
29. Patients with acute heart failure discharged from the emergency department and classified as low risk by the MEESSI score (multiple risk estimate based on the Spanish emergency department scale): prevalence of adverse events and predictability
- Author
-
Miro, Oscar, Gil, Victor, Rossello, Xavier, Javier Martin-Sanchez, Francisco, Llorens, Pere, Jacob, Javier, Herrero, Pablo, Herrera Mateo, Sergio, Richard, Fernando, Escoda, Rosa, Fuentes, Marta, Martin Mojarro, Enrique, Llauger, Lluis, HECTOR BUENO, Pocock, Stuart, Gil, Cristina, Garmila, Pablo, Rodriguez Adrada, Esther, Perdigones, Javier, Escobar, Luis, Xipell, Carolina, Sanchez, Carolina, Ma Gaytan, Josep, Jose Perez-Dura, Maria, Pavon, Jose, Bella Alvarez, Ana, Noval, Antonio, Torres, Jose M., Luisa Lopez-Grima, Maria, Valero, Amparo, Angeles Juan, Marian, Aguirre, Alfons, Angels Pedragosa, Maria, Isabel Alonso, Maria, Ruiz, Francisco, Miguel Franco, Jose, Diaz, Elena, Belen Mecina, Ana, Tost, Josep, Sanchez, Susana, Pinera, Pascual, Torres Garate, Raquel, Alberto Rizzi, Miguel, Herrera, Sergio, Cabello, Irene, Alvarez Perez, Jose Maria, Lopez Diez, Maria Pilar, Vasquez Alvarez, Joaquin, Alonso Morilla, Ana, Irimia, Andrea, Marquina, Victor, Jimenez, Inmaculada, Hernandez, Nestor, Ramos, Sergio, Lopez, Ana, Antonio Andueza, Juan, Romero, Rodolfo, Calvache, Roberto, Teresa Lorca, Maria, Calderon, Luis, Amores Arriaga, Beatriz, Sierra, Beatriz, Traver Becquer, Lisette, Corominas La Salle, Gerard, Aguera Urbano, Carmen, and Soy Ferrer, Ester
- Subjects
Hospitalization ,Emergency department ,Acute heart failure ,Mortality ,Emergency revisits ,Risk assessment - Abstract
Objective. To determine the rate of adverse events in patients with acute heart failure (AHF) who were discharged from the emergency department (ED) after classification as low risk according to MEESSI score (multiple risk estimate based on the Spanish ED scale), to analyze the ability of the score to predict events, and to explore variables associated with adverse events. Methods. Patients in the EAHFE registry (Epidemiology of Acute Heart Failure in EDs) were stratified according to risk indicated by MEESSI score in order to identify those considered at low risk on discharge. All-cause 30-day mortality and revisits related to AHF within 7 days and 30 days were recorded. The area under the receiver operating characteristic curve (AUC) was calculated for the MEESSI score's ability to predict these events. Associations between 42 variables and 7-day and 30-day revisits to the ED were analyzed by multivariable logistic regression. Results. A total of 1028 patients were included. The 30-day mortality rate was 1.6% (95% CI, 0.9%-2.5%). The 7-day and 30-day revisit rates were 8.0% (95% CI, 6.4%-9.8%) and 24.7% (95% CI, 22.1%-25.7%), respectively. The AUCs for MEESSI score discrimination between patients with and without these outcomes were as follows: 30-day mortality, 0.69 (95% CI, 0.58-0.80); 7-day revisiting, 0.56 (95% CI, 0.49-0.63); and 30-day revisiting, 0.54 (95% CI, 0.50-0.59). Variables associated with 7-day revisits were long-term diuretic treatment (odds ratio [OR], 2.45; 95% CI, 1.01-5.98), hemoglobin concentration less than 110 g/L (OR, 1.68; 95% CI, 1.02-2.75), and intravenous diuretic treatment in the ED (OR, 0.53; 95% CI, 0.31-0.90). Variables associated with 30-day revisits were peripheral artery disease (OR, 1.74; 95% CI, 1.01-3.00), prior history of an AHF episode (OR, 1.42; 95% CI, 1.02-1.98), long-term mineralocorticoid receptor antagonist treatment (OR, 1.71; 95% CI, 1.09-2.67), Barthel index less than 90 points in the ED (OR, 1.48; 95% CI, 1.07-2.06), and intravenous diuretic treatment in the ED (OR, 0.58; 95% CI, 0.40-0.84). Conclusions. Patients with AHF who are at low risk for adverse events on discharge from our EDs have event rates that are near internationally recommended targets. The MEESSI score, which was designed to predict 30-day mortality, is a poor predictor of 7-day or 30-day revisiting in these low-risk patients. We identified other factors related to these events.
- Published
- 2019
30. Clinical phenotypes of acute heart failure based on signs and symptoms of perfusion and congestion at emergency department presentation and their relationship with patient management and outcomes
- Author
-
Javaloyes, Patricia Miro, Oscar Gil, Victor Javier Martin-Sanchez, Francisco Jacob, Javier Herrero, Pablo and Takagi, Koji Alquezar-Arbe, Aitor Lopez Diez, Maria Pilar and Martin, Enrique Bibiano, Carlos Escoda, Rosa Gil, Cristina and Fuentes, Marta Llopis Garcia, Guillermo Alvarez Perez, Jose Maria Jerez, Alba Tost, Josep Llauger, Lluis Romero, Rodolfo Manuel Garrido, Jose Rodriguez-Adrada, Esther and Sanchez, Carolina Rossello, Xavier Parissis, John Mebazaa, Alexandre Chioncel, Ovidiu Llorens, Pere Alonso, Hector and Perez-Llantada, Enrique Suarez Cadenas, Mar Xipell, Carolina and Jose Perez-Dura, Maria Salvo, Eva Pavon, Jose Noval, Antonio and Manuel Torres, Jose Luisa Lopez-Grima, Maria Valero, Amparo and Angeles Juan, Maria Aguirre, Alfons Angels Pedragosa, Maria and Minguez Maso, Silvia Isabel Alonso, Maria Ruiz, Francisco and Miguel Franco, Jose Belen Mecina, Ana Berenguer, Marta and Donea, Ruxandra Sanchez Ramon, Susana Carbajosa Rodriguez, Virginia Pinera, Pascual Sanchez Nicolas, Jose Andres Torres Garate, Raquel Alberto Rizzi, Miguel Roset, Alex Cabello, Irene Haro, Antonio Richard, Fernando Lopez Diez, Maria Pilar Vazquez Alvarez, Joaquin Prieto Garcia, Belen Garcia Garcia, Maria Sanchez Gonzalez, Marta Marquina, Victor and Jimenez, Inmaculada Hernandez, Nestor Brouzet, Benjamin and Espinosa, Begona Antonio Andueza, Juan Ruiz, Martin and Calvache, Roberto Lorca Serralta, Maria Teresa Calderon Jave, Luis Ernesto Amores Arriaga, Beatriz Sierra Bergua, Beatriz and Martin Mojarro, Enrique Alarcon Jimenez, Brigitte Silvana and Traveria Becquer, Lisette Burillo, Guillermo Llauger Garcia, Lluis Corominas LaSalle, Gerard Aguera Urbano, Carmen Garcia Soto, Ana Belen Delgado Padial, Elisa Soy Ferrer, Ester and Javier Lucas-Imbernon, Francisco Gaya, Rut Mir, Maria and Rodriguez, Beatriz Luis Carballo, Jose Rodriguez Miranda, Belen and ICA-SEMES Res Grp
- Abstract
Objective To compare the clinical characteristics and outcomes of patients with acute heart failure (AHF) according to clinical profiles based on congestion and perfusion determined in the emergency department (ED). Methods and results Overall, 11 261 unselected AHF patients from 41 Spanish EDs were classified according to perfusion (normoperfusion = warm; hypoperfusion = cold) and congestion (not = dry; yes = wet). Baseline and decompensation characteristics were recorded as were the main wards to which patients were admitted. The primary outcome was 1-year all-cause mortality; secondary outcomes were need for hospitalisation during the index AHF event, in-hospital all-cause mortality, prolonged hospitalisation, 7-day post-discharge ED revisit for AHF and 30-day post-discharge rehospitalisation for AHF. A total of 8558 patients (76.0%) were warm+ wet, 1929 (17.1%) cold+ wet, 675 (6.0%) warm+ dry, and 99 (0.9%) cold+ dry; hypoperfused (cold) patients were more frequently admitted to intensive care units and geriatrics departments, and warm+ wet patients were discharged home without admission. The four phenotypes differed in most of the baseline and decompensation characteristics. The 1-year mortality was 30.8%, and compared to warm+ dry, the adjusted hazard ratios were significantly increased for cold+ wet (1.660; 95% confidence interval 1.400-1.968) and cold+ dry (1.672; 95% confidence interval 1.189-2.351). Hypoperfused (cold) phenotypes also showed higher rates of index episode hospitalisation and in-hospital mortality, while congestive (wet) phenotypes had a higher risk of prolonged hospitalisation but decreased risk of rehospitalisation. No differences were observed among phenotypes in ED revisit risk. Conclusions Bedside clinical evaluation of congestion and perfusion of AHF patients upon ED arrival and classification according to phenotypic profiles proposed by the latest European Society of Cardiology guidelines provide useful complementary information and help to rapidly predict patient outcomes shortly after ED patient arrival.
- Published
- 2019
31. Two-Hour Algorithm for Rapid Triage of Suspected Acute Myocardial Infarction Using a High-Sensitivity Cardiac Troponin I Assay
- Author
-
Nestelberger, Thomas, primary, Boeddinghaus, Jasper, additional, Greenslade, Jaimi, additional, Parsonage, William A, additional, Than, Martin, additional, Wussler, Desiree, additional, Lopez-Ayala, Pedro, additional, Zimmermann, Tobias, additional, Meier, Mario, additional, Troester, Valentina, additional, Badertscher, Patrick, additional, Koechlin, Luca, additional, Wildi, Karin, additional, Anwar, Mahnoor, additional, Freese, Michael, additional, Keller, Dagmar I, additional, Reichlin, Tobias, additional, Twerenbold, Raphael, additional, Cullen, Louise, additional, Mueller, Christian, additional, Puelacher, Christian, additional, du Fay de Lavallaz, Jeanne, additional, Rubini Giménez, Maria, additional, Strebel, Ivo, additional, Walter, Joan, additional, Huber, Jeffrey, additional, Christ, Michael, additional, Kozhuharov, Nikola, additional, Gualandro, Danielle M, additional, Potlukova, Eliska, additional, Baumgartner, Benjamin, additional, Hafner, Benjamin, additional, Rentsch, Katharina, additional, Miró, Òscar, additional, Fuenzalida, Carolina, additional, Gil, Beatriz, additional, Martin-Sanchez, F Javier, additional, Kawecki, Damian, additional, Geigy, Nicolas, additional, Meissner, Kathrin, additional, Kulangara, Caroline, additional, López, Beatriz, additional, Rodriguez Adrada, Esther, additional, Ganovská, Eva, additional, Lohrmann, Jens, additional, Kloos, Wanda, additional, Steude, Jana, additional, Buser, Andreas, additional, von Eckardstein, Arnold, additional, Nowalany-Kozielska, Ewa, additional, and Muzyk, Piotr, additional
- Published
- 2019
- Full Text
- View/download PDF
32. Clinical Use of a New High-Sensitivity Cardiac Troponin I Assay in Patients with Suspected Myocardial Infarction
- Author
-
Boeddinghaus, Jasper, primary, Twerenbold, Raphael, additional, Nestelberger, Thomas, additional, Koechlin, Luca, additional, Wussler, Desiree, additional, Meier, Mario, additional, Troester, Valentina, additional, Zimmermann, Tobias, additional, Badertscher, Patrick, additional, Wildi, Karin, additional, Rubini Giménez, Maria, additional, Lopez-Ayala, Pedro, additional, Potlukova, Eliska, additional, Miró, Òscar, additional, Martin-Sanchez, F Javier, additional, Kawecki, Damian, additional, Geigy, Nicolas, additional, Keller, Dagmar I, additional, Reichlin, Tobias, additional, Mueller, Christian, additional, du Fay de Lavallaz, Jeanne, additional, Walter, Joan Elias, additional, Freese, Michael, additional, Puelacher, Christian, additional, Hafner, Benjamin, additional, Strebel, Ivo, additional, Kozhuharov, Nikola, additional, Rentsch, Katharina, additional, Gualandro, Danielle M, additional, Schaerli, Nicolas, additional, Stelzig, Claudia, additional, Meissner, Kathrin, additional, Kulangara, Caroline, additional, Hillinger, Petra, additional, Grimm, Karin, additional, Michou, Eleni, additional, Flores, Dayana, additional, Czmok, Rafael, additional, Osswald, Stefan, additional, López, Beatriz, additional, Fuenzalida, Carolina, additional, Rodriguez Adrada, Esther, additional, Ganovská, Eva, additional, Lohrmann, Jens, additional, Kloos, Wanda, additional, Christ, Michael, additional, Steude, Jana, additional, Fahrni, Gregor, additional, Buser, Andreas, additional, von Eckardstein, Arnold, additional, Morawiec, Beata, additional, Nowalany-Kozielska, Ewa, additional, and Muzyk, Piotr, additional
- Published
- 2019
- Full Text
- View/download PDF
33. Circadian, weekly, seasonal, and temperature-dependent patterns of syncope aetiology in patients at increased risk of cardiac syncope.
- Author
-
Lavallaz, Jeanne du Fay de, Badertscher, Patrick, Nestelberger, Thomas, Flores, Dayana, Miró, Òscar, Salgado, Emilio, Geigy, Nicolas, Christ, Michael, Cullen, Louise, Than, Martin, Martin-Sanchez, F Javier, Rodriguez-Adrada, Esther, Somma, Salvatore Di, Peacock, W Frank, Kawecki, Damian, Boeddinghaus, Jasper, Twerenbold, Raphael, Puelacher, Christian, Wussler, Desiree, and Strebel, Ivo
- Abstract
Aims: It is unknown whether cardiac syncope, and possibly also other syncope aetiologies exhibit circadian, weekly, seasonal, and temperature-dependent patterns.Methods and Results: We prospectively recorded the exact time, date, and outside temperature of syncope of patients >40 years old presenting with syncope to the emergency department in a diagnostic multicentre study. Two independent cardiologists/emergency physicians adjudicated the final diagnosis based on all information becoming available during clinical work-up including 1-year follow-up. Among 1230 patients, the adjudicated aetiology was cardiac in 14.6%, reflex in 39.2%, orthostatic in 25.7%, other non-cardiac in 9.7%, and unknown in 10.8% of patients. All syncope aetiologies occurred much more frequently during the day when compared with the night (P < 0.01). While reflex and orthostatic syncope showed a broad peak of prevalence with 80.9% of these events occurring between 4 am and 4 pm, cardiac syncope showed a narrow peak of prevalence with 70.1% of all events occurring between 8 am and 2 pm. A weekly pattern was present for most syncope aetiologies, with events occurring mainly from Monday to Friday (P < 0.01). Reflex syncope displayed a seasonal rhythm and was more common in winter (P < 0.01), while cardiac syncope stayed constant over the year. Syncope occurred most often when the outside temperature was coldest. Overall the patterns observed for cardiac syncope were similar to the patterns observed for its differential diagnosis.Conclusion: Syncope aetiologies in patients >40 years old display circadian, weekly, seasonal, and temperature-dependent patterns. Unfortunately, these patterns do not allow to reliably differentiate cardiac syncope from other aetiologies. [ABSTRACT FROM AUTHOR]- Published
- 2019
- Full Text
- View/download PDF
34. Considerations on the prognosis of patients with pulmonary embolism
- Author
-
Rodríguez Adrada, Esther, Espinosa, Begoña, and Calvo Porqueras, Beatriz
- Published
- 2019
- Full Text
- View/download PDF
35. Consideraciones sobre el pronóstico de los pacientes con tromboembolia pulmonar
- Author
-
Rodríguez Adrada, Esther, Espinosa, Begoña, and Calvo Porqueras, Beatriz
- Published
- 2019
- Full Text
- View/download PDF
36. Aspects to be clarified on the prognostic role of the systolic arterial pressure in heart failure
- Author
-
Yañez-Palma, María Cecilia, Llopis García, Guillermo, and Rodríguez Adrada, Esther
- Published
- 2018
- Full Text
- View/download PDF
37. Aspectos por dilucidar sobre el papel pronóstico de la presión arterial sistólica en la insuficiencia cardiaca
- Author
-
Yañez-Palma, María Cecilia, Llopis García, Guillermo, and Rodríguez Adrada, Esther
- Published
- 2018
- Full Text
- View/download PDF
38. Chronic obstructive pulmonary disease and community acquired pneumonia: Much more to clarify
- Author
-
del Carmen Santos, María, Tornero, Fernando, Núñez Orantos, María José, Rodríguez Adrada, Esther, and González del Castillo, Juan
- Published
- 2018
- Full Text
- View/download PDF
39. Ahorro de antibióticos prescritos en faringitis e infecciones del tracto respiratorio inferior en Atención Primaria
- Author
-
Beddar Chaib, Fahd, Mostaza Gallar, Paula, Rodríguez Adrada, Esther, and González del Castillo, Juan
- Published
- 2018
- Full Text
- View/download PDF
40. Staphylococcus aureus infections and factors associated with resistance to methicillin in a hospital emergency department.
- Author
-
González-Castillo, Juan, Cenci, Caterina, Rodriguez-Adrada, Esther, Javier Candel, Francisco, de la Torre-Misiego, Fernando, Fernández, Cristina, and Javier Martín-Sánchez, Francisco
- Subjects
METHICILLIN-resistant staphylococcus aureus ,STAPHYLOCOCCUS aureus infections ,HOSPITAL emergency services ,LOGISTIC regression analysis ,ANTIBIOTICS - Abstract
Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2013
41. Diagnostic groups and short-term outcomes in suspected COVID-19 cases treated in an emergency department
- Author
-
Javier Martin-Sanchez, F., Gonzalez Del Castillo, Juan, Valls Carbo, Adrian, Lopez Picado, Amanda, Martinez-Valero, Carmen, Miranda, Juande D., Chacon, Ana, Lopez-Ayala, Pedro, Chaparro, David, Cozar Lopez, Gabriel, Del Mar Suarez-Cadenas, Maria, Jerez Fernandez, Pablo, Del Toro, Enrique, Cardassay, Eduardo, Angos, Beatriz, Cristina Díaz del Arco, Rodriguez Adrada, Esther, Montalvo Moraleda, Maria Teresa, Espejo Paeres, Carolina, Elvira, Carlos, Garcia Brinon, Miguel Angel, Leal Pozuelo, Jose Ma, Ortega, Luis, Fernandez Perez, Cristina, and Gonzalez Armengol, Juan Jorge
- Subjects
Adult ,Male ,Time Factors ,SARS-CoV-2 ,Pneumonia, Viral ,COVID-19 ,Comorbidity ,Middle Aged ,Polymerase Chain Reaction ,Betacoronavirus ,Treatment Outcome ,Spain ,Cause of Death ,Confidence Intervals ,Humans ,Female ,Registries ,Symptom Assessment ,Coronavirus Infections ,Emergency Service, Hospital ,Pandemics ,Diagnosis-Related Groups - Abstract
The primary objective was to describe the clinical characteristics and 30-day mortality rates in emergency department patients with coronavirus disease 2019 (COVID-19) in different diagnostic groupings.Secondary analysis of the COVID-19 registry compiled by the emergency department of Hospital Clínico San Carlos in Madrid, Spain. We selected suspected COVID-19 cases treated in the emergency department between February 28 and March 31, 2020. The cases were grouped as follows: 1) suspected, no polymerase chain reaction (PCR) test (S/no-PCR); 2) suspected, negative PCR (S/PCR-); 3) suspected, positive PCR (S/PCR+); 4) highly suspected, no PCR, or negative PCR (HS/no or PCR-); and 5) highly suspected, positive PCR (HS/PCR+). We collected clinical, radiologic, and microbiologic data related to the emergency visit. The main outcome was 30-day all-cause mortality. Secondary outcomes were hospitalization and clinical severity of the episode.A total of 1993 cases (90.9%) were included as follows: S/no-PCR, 17.2%; S/PCR-, 11.4%; S/PCR+, 22.1%; HS/no PCR or PCR-, 11.7%; and HS/PCR+, 37.6%. Short-term outcomes differed significantly in the different groups according to demographic characteristics; comorbidity and clinical, radiographic, analytical, and therapeutic variables. Thirty-day mortality was 11.5% (56.5% in hospitalized cases and 19.6% in cases classified as severe). The 2 HS categories and the S/PCR+ category had a greater adjusted risk for 30-day mortality and for having a clinically severe episode during hospitalization in comparison with S/PCR- cases. Only the 2 HS categories showed greater risk for hospitalization than the S/PCR- cases.COVID-19 diagnostic groups differ according to clinical and laboratory characteristics, and the differences are associated with the 30-day prognosis.El objetivo principal fue describir el perfil clínico y la mortalidad a los 30 días de diferentes categorías diagnósticas en los casos de COVID-19 atendidos en un servicio de urgencias (SU).Análisis secundario del registro COVID-19_URG-HCSC. Se seleccionaron los casos sospechosos de COVID-19 atendidos en un SU de Madrid desde el 28 de febrero hasta el 31 de marzo de 2020. La muestra se dividió: 1) sospecha con PCR no realizada (S/PCR NR); 2) sospecha con PCR negativa (S/PCR–); 3) sospecha con PCR positiva (S/ PCR+); 4) alta sospecha con PCR negativa o no realizada (AS/PCR– o NR); y 5) alta sospecha con PCR positiva (AS/ PCR+). Se recogieron variables clínicas, radiológicas y microbiológicas del episodio de urgencias. La variable de resultado principal fue la mortalidad por cualquier causa a los 30 días. Las variables secundarias fueron el ingreso y la gravedad del episodio.Se incluyeron 1.993 pacientes; 17,2% S/PCR NR, 11,4% S/PCR–, 22,1% S/PCR+, 11,7% AS/PCR– o NR y 37,6% AS/PCR+. Se hallaron diferencias estadísticamente significativas respecto a las variables demográficas, comorbilidad, clínicas, radiográficas, analíticas y terapéuticas y de resultados a corto plazo en función las categorías diagnósticas. La mortalidad global a los 30 días fue de un 11,5%, 56,5% casos fueron hospitalizados y 19,6% casos sufrieron un episodio grave. Las categorías de AS y de S/PCR+ tuvieron un incremento del riesgo ajustado de mortalidad a los 30 días y de sufrir un episodio grave durante el ingreso hospitalario respecto a S/PCR–. En relación al ingreso, solo las categorías de AS tuvieron un incremento del riesgo ajustado de hospitalización respecto a la categoría de S/PCR–.Existen diferentes categorías diagnósticas de la enfermedad COVID-19 en función del perfil clínico y microbiológico que tienen correlato con el pronóstico a 30 días.
42. Comparison of different strategies for short-term death prediction in the infected older patient
- Author
-
Cecilia Yanez, Maria, Salido Mota, Manuel, Fuentes Ferrer, Manuel, Julian-Jimenez, Agustin, Pinera, Pascual, Llopis, Ferran, Gamazo Del Rio, Julio, Ortiz Zarate, Mikel Martinez, Angel Estella, Javier Martin-Sanchez, Francisco, Gonzalez Del Castillo, Juan, Herrero Puente, Pablo, Rubio Diaz, Rafael, Moya Olmeda, Diana, Lopez Izquierdo, Raul, Sanchez Nicolas, Jose Andres, Alvarez Hurtado, Angel Aurelio, Del Pozo Vegas, Carlos, Gallardo Bautista, Jose, Javier Candel, Francisco, Cobanera Echebarria, Borja, Roman, Francisco, Llorens, Pere, Perales, Ramon, Onate, Javier, Mora Ordonez, Begona, Fragero, Eva, Ortega, Mar, Burillo, Guillermo, Gomez Hernandez, Carolina, Jesus Arranz, Maria, Juarez, Ricardo, Ferreras Amez, Jose Maria, Muro, Eva, Perez Ordono, Luis, Garcia Criado, Jorge, Wernitz, Andres, Del Arco, Carmen, Marchena Yglesias, Pablo Javier, Ruiz, Francisco, Garcia Castrillo, Luis, Alonso, Hector, Salido, Manuel, Rodriguez Miranda, Belen, Ruiz Grinspan, Martin, Guardiola Tey, Josep Maria, Herrera Mateo, Sergio, Mateo Roca, Miriam, Jose Ezponda, Francisco, Diez, Elena, Gracia Garcia, Francisco, Huarte, Itziar, Gayoso Martin, Sara, Cubillo Moreno, Maria, Juarez Sosa, Silvia, La Chica, Ana, Ferre Losa, Carles, Del Rio Navarro, Rigoberto, Iglesias Vela, Marta, Maestro Gilmartin, Luis Miguel, Avellaneda Martinez, Carlos, Alvarez Rodriguez, Virginia, Fernandez Rodriguez, Manuel, Guiu Marti, Alexandra Maria, Salmeron Beliz, Octavio J., Flores Quesada, Silvia, Troiano Ungerer, Osvaldo, Cano Rodriguez, Tania, Lapuerta Irigoyen, Luis, Andonegui, Carmen, Cortes, Nieves, Munoz Gamito, Gema, Valle Borrego, Beatriz, Arranz Betegon, Maria, Sierra Moreno, Angel, Chanovas Borras, Manel R., Urraca Gamaury, Ainhoa, Cruzado Quevedo, Jesus, Carpio Munoz, Veronica, Marchante Tejada, Cristobal, Menchaca, Bakarne, Modol Deltell, Josep Maria, Macias Lopez, Angel, Angeles Lecinera, Maria, Sarra Moreto, Salvador, Suero Mendez, Coral, Pendon Fernandez, Salvador, Rodriguez, Raimundo, Cardenete Aljama, Miguel Angel, Fernandez Rivas, Maite, Amador, Luis, Cobo Munoz, Jose Eduardo, Carrasco, Elena, Rodriguez Salazar, David, Nunez Orantos, Maria Jose, and Rodriguez Adrada, Esther
- Subjects
sepsis ,qSOFA ,emergency ,SIRS ,infected older patient ,prognosis ,mortality - Abstract
Objective. The aim of this study was to determine the utility of a post hoc lactate added to SIRS and qSOFA score to predict 30-day mortality in older non-severely dependent patients attended for infection in the Emergency Department (ED). Methods. We performed an analytical, observational, prospective cohort study including patients of 75 years of age or older, without severe functional dependence, attended for an infectious disease in 69 Spanish ED for 2-day three seasonal periods. Demographic, clinical and analytical data were collected. The primary outcome was 30-day mortality after the index event. Results. We included 739 patients with a mean age of 84.9 (SD 6.0) years; 375 (50.7%) were women. Ninety-one (12.3%) died within 30 days. The AUC was 0.637 (IC 95% 0.587-0.688; p= 2 and 0.698 (IC 95% 0.635- 0.761; p= 2. Comparing receiver operating characteristic (ROC) there was a better accuracy of qSOFA vs SIRS (p=0.041). Both scales improve the prognosis accuracy with lactate inclusion. The AUC was 0.705 (IC95% 0.652-0.758; p
43. Impact of geriatric assessment variables on 30-day mortality among older patients with acute heart failure
- Author
-
Javier Martin-Sanchez, Francisco, Rodriguez-Adrada, Esther, Teresa Vidan, Maria, Diez Villanueva, Pablo, Llopis Garcia, Guillermo, Gonzalez Del Castillo, Juan, Alberto Rizzi, Miguel, Alquezar, Aitor, Herrera Mateo, Sergio, Pinera, Pascual, Sanchez Nicolas, Jose Andres, Lazaro Aragues, Paula, Llorens, Pere, Herrero, Pablo, Jacob, Javier, Gill, Victor, Fernandez, Cristina, HECTOR BUENO, and Miro, Oscar
- Subjects
Disability ,Frailty ,Patients ,Confusional state ,Mortalitat ,Acute heart failure ,Heart failure ,Insuficiència cardíaca ,Pacients ,Mortality ,Older people ,Persones grans - Abstract
Objective. To study the impact of geriatric assessment variables on 30-day mortality among older patients with acute heart failure (AHF). Methods. Retrospective analysis of cases in the OAK Registry (Older Acute Heart Failure Key Data), a prospectively compiled database of consecutive patients aged 65 years or older treated for AHF in 3 Spanish emergency departments over a 4-month period (November-December 2011 and January-February 2014). The patients underwent a geriatric assessment adapted for emergency department use on weekdays between 8 AM and 10 PM. Demographic, clinical, laboratory, and geriatric assessment variables were recorded. The geriatric variables were concurrent diseases; polypharmacy; frailty; functional, social, and cognitive status at baseline; results of screening for confusional state, cognitive impairment, and depression; and nutritional status. The primary outcome was all-cause mortality at 30 days. Results. We included 565 patients with a mean (SD) age of 83 (7.1) years; 346 (61.6%) were women. Sixty-five (11.5%) died within 30 days. Independent factors associated with 30-day mortality were acute confusional state (adjusted odds ratio [aOR], 2.2; 95% CI, 1.0-4.8; P=.04), acute illness (aOR, 1.8; 95% CI, 0.9-3.4; P=.05), loss of appetite in the past 3 months (aOR, 1.8; 95% CI, 1.0-3.4; P=.04), frailty (aOR, 2.0, 95% CI, 1.0-4.1; P=.05), and severe disability (aOR, 4.4; 95% CI, 1.9-11.4; P=.01). Conclusions. Certain geriatric variables should be considered when assessing short-term risk in older patients with AHF.
44. Circadian, weekly, seasonal, and temperature-dependent patterns of syncope aetiology in patients at increased risk of cardiac syncope.
- Author
-
du Fay de Lavallaz J, Badertscher P, Nestelberger T, Flores D, Miró Ò, Salgado E, Geigy N, Christ M, Cullen L, Than M, Martin-Sanchez FJ, Rodriguez-Adrada E, Di Somma S, Peacock WF, Kawecki D, Boeddinghaus J, Twerenbold R, Puelacher C, Wussler D, Strebel I, Keller DI, Poepping I, Kühne M, Reichlin T, and Mueller C
- Subjects
- Adult, Aged, Aged, 80 and over, Australia epidemiology, Europe epidemiology, Female, Humans, Male, Middle Aged, New Zealand epidemiology, Prevalence, Prospective Studies, Risk Factors, Syncope diagnosis, Syncope physiopathology, Time Factors, United States epidemiology, Circadian Rhythm, Seasons, Syncope epidemiology, Temperature
- Abstract
Aims: It is unknown whether cardiac syncope, and possibly also other syncope aetiologies exhibit circadian, weekly, seasonal, and temperature-dependent patterns., Methods and Results: We prospectively recorded the exact time, date, and outside temperature of syncope of patients >40 years old presenting with syncope to the emergency department in a diagnostic multicentre study. Two independent cardiologists/emergency physicians adjudicated the final diagnosis based on all information becoming available during clinical work-up including 1-year follow-up. Among 1230 patients, the adjudicated aetiology was cardiac in 14.6%, reflex in 39.2%, orthostatic in 25.7%, other non-cardiac in 9.7%, and unknown in 10.8% of patients. All syncope aetiologies occurred much more frequently during the day when compared with the night (P < 0.01). While reflex and orthostatic syncope showed a broad peak of prevalence with 80.9% of these events occurring between 4 am and 4 pm, cardiac syncope showed a narrow peak of prevalence with 70.1% of all events occurring between 8 am and 2 pm. A weekly pattern was present for most syncope aetiologies, with events occurring mainly from Monday to Friday (P < 0.01). Reflex syncope displayed a seasonal rhythm and was more common in winter (P < 0.01), while cardiac syncope stayed constant over the year. Syncope occurred most often when the outside temperature was coldest. Overall the patterns observed for cardiac syncope were similar to the patterns observed for its differential diagnosis., Conclusion: Syncope aetiologies in patients >40 years old display circadian, weekly, seasonal, and temperature-dependent patterns. Unfortunately, these patterns do not allow to reliably differentiate cardiac syncope from other aetiologies., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2018. For permissions, please email: journals.permissions@oup.com.)
- Published
- 2019
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.