248 results on '"Rodrigues, Cecília M.P."'
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2. Impact of Lactobacillaceae supplementation on the multi-organ axis during MASLD
3. Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration
4. NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease
5. Anti-integrin αvβ6 Autoantibodies are Increased in Primary Sclerosing Cholangitis Patients With Concomitant Inflammatory Bowel Disease and Correlate With Liver Disease Severity
6. ARBM101 (Methanobactin SB2) Drains Excess Liver Copper via Biliary Excretion in Wilson’s Disease Rats
7. A step forward on the in vitro and in vivo assessment of a novel nanomedicine against melanoma
8. Preclinical validation of a new hybrid molecule loaded in liposomes for melanoma management
9. Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors
10. The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes
11. Disclosing the antitumour potential of the marine bromoditerpene sphaerococcenol A on distinct cancer cellular models
12. Methylone screening with electropolymerized molecularly imprinted polymer on screen-printed electrodes
13. Lytic cell death in metabolic liver disease
14. Targeted Avenues for Cancer Treatment: The MEK5–ERK5 Signaling Pathway
15. Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease
16. Electrochemical sensing of ecstasy with electropolymerized molecularly imprinted poly(o-phenylenediamine) polymer on the surface of disposable screen-printed carbon electrodes
17. Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
18. NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease
19. Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration
20. Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties
21. In vitro targeting of colon cancer cells using spiropyrazoline oxindoles
22. Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury
23. Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease
24. N-acetylcysteine treatment attenuates the cognitive impairment and synaptic plasticity loss induced by streptozotocin
25. Molecular mechanisms of necroptosis and relevance for neurodegenerative diseases
26. Decoding the role of leptin and adiponectin in obesity-related gastrointestinal cancer
27. The MEK5/ERK5 signalling pathway in cancer: a promising novel therapeutic target
28. miR-21-5p promotes NASH-related hepatocarcinogenesis
29. Preclinical validation of a new hybrid molecule loaded in liposomes for melanoma management
30. Role of TGR5 in fat-to-liver communication during NAFLD
31. Deoxycholic acid modulates cell death signaling through changes in mitochondrial membrane properties
32. Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset
33. Synthesis and evaluation of spiroisoxazoline oxindoles as anticancer agents
34. Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations
35. p,p′-Methoxyl-diphenyl diselenide protects against amyloid-β induced cytotoxicity in vitro and improves memory deficits in vivo
36. Delivering the promise of miRNA cancer therapeutics
37. Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice
38. Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice
39. Death receptors and mitochondria: Two prime triggers of neural apoptosis and differentiation
40. miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease
41. Circulating miR-21 parallels the incidence of IBD in PSC patients
42. Is there a murine model that fully recapitulates human NASH? An unbiased bioinformatics approach to rank pre-clinical models based on proximity to human disease
43. Contrasting apoptotic responses of conjugated linoleic acid in the liver of obese Zucker rats fed palm oil or ovine fat
44. Colorectal cancer: Can nutrients modulate NF-κB and apoptosis?
45. Signalling networks in cholangiocarcinoma: Molecular pathogenesis, targeted therapies and drug resistance
46. Bile acids: regulation of apoptosis by ursodeoxycholic acid
47. p53 and the regulation of hepatocyte apoptosis: implications for disease pathogenesis
48. Naphtho[2,3- d]isoxazole-4,9-dione-3-carboxylates: Potent, non-cytotoxic, antiapoptotic agents
49. Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease
50. Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53
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