9 results on '"Rodrigo Octávio Deliberato"'
Search Results
2. Physician satisfaction with a multi-platform digital scheduling system.
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Rodrigo Octávio Deliberato, Leonardo Lima Rocha, Alex Heitor Lima, Caroline Reis Maia Santiago, Jose Cláudio Cyrineu Terra, Alon Dagan, and Leo Anthony Celi
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Medicine ,Science - Abstract
OBJECTIVE:Physician shift schedules are regularly created manually, using paper or a shared online spreadsheet. Mistakes are not unusual, leading to last minute scrambles to cover a shift. We developed a web-based shift scheduling system and a mobile application tool to facilitate both the monthly scheduling and shift exchanges between physicians. The primary objective was to compare physician satisfaction before and after the mobile application implementation. METHODS:Over a 9-month period, three surveys, using the 4-point Likert type scale were performed to assess the physician satisfaction. The first survey was conducted three months prior mobile application release, a second survey three months after implementation and the last survey six months after. RESULTS:51 (77%) of the physicians answered the baseline survey. Of those, 32 (63%) were males with a mean age of 37.8 ± 5.5 years. Prior to the mobile application implementation, 36 (70%) of the responders were using more than one method to carry out shift exchanges and only 20 (40%) were using the official department report sheet to document shift exchanges. The second and third survey were answered by 48 (73%) physicians. Forty-eight (98%) of them found the mobile application easy or very easy to install and 47 (96%) did not want to go back to the previous method. Regarding physician satisfaction, at baseline 37% of the physicians were unsatisfied or very unsatisfied with shift scheduling. After the mobile application was implementation, only 4% reported being unsatisfied (OR = 0.11, p < 0.001). The satisfaction level improved from 63% to 96% between the first and the last survey. Satisfaction levels significantly increased between the three time points (OR = 13.33, p < 0.001). CONCLUSION:Our web and mobile phone-based scheduling system resulted in better physician satisfaction.
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- 2017
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3. Inaccuracy of Venous Point-of-Care Glucose Measurements in Critically Ill Patients: A Cross-Sectional Study.
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Adriano José Pereira, Thiago Domingos Corrêa, Francisca Pereira de Almeida, Rodrigo Octávio Deliberato, Michelle dos Santos Lobato, Nelson Akamine, Eliézer Silva, and Alexandre Biasi Cavalcanti
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Medicine ,Science - Abstract
Current guidelines and consensus recommend arterial and venous samples as equally acceptable for blood glucose assessment in point-of-care devices, but there is limited evidence to support this recommendation. We evaluated the accuracy of two devices for bedside point-of-care blood glucose measurements using arterial, fingerstick and catheter venous blood samples in ICU patients, and assessed which factors could impair their accuracy.145 patients from a 41-bed adult mixed-ICU, in a tertiary care hospital were prospectively enrolled. Fingerstick, central venous (catheter) and arterial blood (indwelling catheter) samples were simultaneously collected, once per patient. Arterial measurements obtained with Precision PCx, and arterial, fingerstick and venous measurements obtained with Accu-chek Advantage II were compared to arterial central lab measurements. Agreement between point-of-care and laboratory measurements were evaluated with Bland-Altman, and multiple linear regression models were used to investigate interference of associated factors.Mean difference between Accu-chek arterial samples versus central lab was 10.7 mg/dL (95% LA -21.3 to 42.7 mg/dL), and between Precision PCx versus central lab was 18.6 mg/dL (95% LA -12.6 to 49.5 mg/dL). Accu-chek fingerstick versus central lab arterial samples presented a similar bias (10.0 mg/dL) but a wider 95% LA (-31.8 to 51.8 mg/dL). Agreement between venous samples with arterial central lab was the poorest (mean bias 15.1 mg/dL; 95% LA -51.7 to 81.9). Hyperglycemia, low hematocrit, and acidosis were associated with larger differences between arterial and venous blood measurements with the two glucometers and central lab. Vasopressor administration was associated with increased error for fingerstick measurements.Sampling from central venous catheters should not be used for glycemic control in ICU patients. In addition, reliability of the two evaluated glucometers was insufficient. Error with Accu-chek Advantage II increases mostly with central venous samples. Hyperglycemia, lower hematocrit, acidosis, and vasopressor administration increase measurement error.
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- 2015
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4. Catheter related bloodstream infection (CR-BSI) in ICU patients: making the decision to remove or not to remove the central venous catheter.
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Rodrigo Octávio Deliberato, Alexandre R Marra, Thiago Domingos Corrêa, Marinês Dalla Vale Martino, Luci Correa, Oscar Fernando Pavão Dos Santos, and Michael B Edmond
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Medicine ,Science - Abstract
BackgroundApproximately 150 million central venous catheters (CVC) are used each year in the United States. Catheter-related bloodstream infections (CR-BSI) are one of the most important complications of the central venous catheters (CVCs). Our objective was to compare the in-hospital mortality when the catheter is removed or not removed in patients with CR-BSI.MethodsWe reviewed all episodes of CR-BSI that occurred in our intensive care unit (ICU) from January 2000 to December 2008. The standard method was defined as a patient with a CVC and at least one positive blood culture obtained from a peripheral vein and a positive semi quantitative (>15 CFU) culture of a catheter segment from where the same organism was isolated. The conservative method was defined as a patient with a CVC and at least one positive blood culture obtained from a peripheral vein and one of the following: (1) differential time period of CVC culture versus peripheral culture positivity of more than 2 hours, or (2) simultaneous quantitative blood culture with ≥ 5:1 ratio (CVC versus peripheral).Results53 CR-BSI (37 diagnosed by the standard method and 16 by the conservative method) were diagnosed during the study period. There was a no statistically significant difference in the in-hospital mortality for the standard versus the conservative method (57% vs. 75%, p = 0.208) in ICU patients.ConclusionIn our study there was a no statistically significant difference between the standard and conservative methods in-hospital mortality.
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- 2012
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5. Evaluation of Evolving Sepsis Screening Criteria in Discriminating Suspected Sepsis and Mortality Among Adult Patients Admitted to the Intensive Care Unit
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Teresa A. Rincon, Jesse Raffa, Leo Anthony Celi, Omar Badawi, Alistair E.W. Johnson, Tom Pollard, Rodrigo Octávio Deliberato, and Janet D. Pierce
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General Nursing - Published
- 2023
6. Gene Expression Scoring of Immune Activity Levels for Precision Use of Hydrocortisone in Vasodilatory Shock
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Lijing Yao, Diego Ariel Rey, Lucas Bulgarelli, Rachel Kast, Jeff Osborn, Emily Van Ark, Li Tai Fang, Bayo Lau, Hugo Lam, Leonardo Maestri Teixeira, Ary Serpa Neto, Rinaldo Bellomo, and Rodrigo Octávio Deliberato
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Male ,Hydrocortisone ,Anti-Inflammatory Agents ,Immunity ,Gene Expression ,Shock ,Middle Aged ,Critical Care and Intensive Care Medicine ,Emergency Medicine ,Humans ,Female ,Precision Medicine ,Aged ,Retrospective Studies - Abstract
Among patients with vasodilatory shock, gene expression scores may identify different immune states. We aimed to test whether such scores are robust in identifying patients' immune state and predicting response to hydrocortisone treatment in vasodilatory shock.We selected genes to generate continuous scores to define previously established subclasses of sepsis. We used these scores to identify a patient's immune state. We evaluated the potential for these states to assess the differential effect of hydrocortisone in two randomized clinical trials of hydrocortisone versus placebo in vasodilatory shock.We initially identified genes associated with immune-adaptive, immune-innate, immune-coagulant functions. From these genes, 15 were most relevant to generate expression scores related to each of the functions. These scores were used to identify patients as immune-adaptive prevalent (IA-P) and immune-innate prevalent (IN-P). In IA-P patients, hydrocortisone therapy increased 28-day mortality in both trials (43.3% vs 14.7%, P = 0.028) and (57.1% vs 0.0%, P = 0.99). In IN-P patients, this effect was numerically reversed.Gene expression scores identified the immune state of vasodilatory shock patients, one of which (IA-P) identified those who may be harmed by hydrocortisone. Gene expression scores may help advance the field of personalized medicine.
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- 2022
7. Identification of acute respiratory distress syndrome subphenotypes de novo using routine clinical data
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Abhijit Duggal, Rachel Kast, Emily Van Ark, Lucas Bulgarelli, Matthew T Siuba, Jeff Osborn, Diego Ariel Rey, Fernando G Zampieri, Alexandre Biasi Cavalcanti, Israel Maia, Denise M Paisani, Ligia N Laranjeira, Ary Serpa Neto, Rodrigo Octávio Deliberato, and Intensive Care Medicine
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Adult ,Respiratory Distress Syndrome ,Time Factors ,Intensive Care ,General Medicine ,Medicine ,Humans ,respiratory medicine (see thoracic medicine) ,Blood Coagulation Tests ,adult intensive & critical care ,Biomarkers ,Retrospective Studies - Abstract
ObjectivesThe acute respiratory distress syndrome (ARDS) is a heterogeneous condition, and identification of subphenotypes may help in better risk stratification. Our study objective is to identify ARDS subphenotypes using new simpler methodology and readily available clinical variables.SettingThis is a retrospective Cohort Study of ARDS trials. Data from the US ARDSNet trials and from the international ART trial.Participants3763 patients from ARDSNet data sets and 1010 patients from the ART data set.Primary and secondary outcome measuresThe primary outcome was 60-day or 28-day mortality, depending on what was reported in the original trial. K-means cluster analysis was performed to identify subgroups. Sets of candidate variables were tested to assess their ability to produce different probabilities for mortality in each cluster. Clusters were compared with biomarker data, allowing identification of subphenotypes.ResultsData from 4773 patients were analysed. Two subphenotypes (A and B) resulted in optimal separation in the final model, which included nine routinely collected clinical variables, namely heart rate, mean arterial pressure, respiratory rate, bilirubin, bicarbonate, creatinine, PaO2, arterial pH and FiO2. Participants in subphenotype B showed increased levels of proinflammatory markers, had consistently higher mortality, lower number of ventilator-free days at day 28 and longer duration of ventilation compared with patients in the subphenotype A.ConclusionsRoutinely available clinical data can successfully identify two distinct subphenotypes in adult ARDS patients. This work may facilitate implementation of precision therapy in ARDS clinical trials.
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- 2022
8. Impact of sex on use of low tidal volume ventilation in invasively ventilated ICU patients-A mediation analysis using two observational cohorts.
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Pien Swart, Rodrigo Octavio Deliberato, Alistair E W Johnson, Tom J Pollard, Lucas Bulgarelli, Paolo Pelosi, Marcelo Gama de Abreu, Marcus J Schultz, and Ary Serpa Neto
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Medicine ,Science - Abstract
BackgroundStudies in patients receiving invasive ventilation show important differences in use of low tidal volume (VT) ventilation (LTVV) between females and males. The aims of this study were to describe temporal changes in VT and to determine what factors drive the sex difference in use of LTVV.Methods and findingsThis is a posthoc analysis of 2 large longitudinal projects in 59 ICUs in the United States, the 'Medical information Mart for Intensive Care III' (MIMIC III) and the 'eICU Collaborative Research DataBase'. The proportion of patients under LTVV (median VT < 8 ml/kg PBW), was the primary outcome. Mediation analysis, a method to dissect total effect into direct and indirect effects, was used to understand which factors drive the sex difference. We included 3614 (44%) females and 4593 (56%) males. Median VT declined over the years, but with a persistent difference between females (from median 10.2 (9.1 to 11.4) to 8.2 (7.5 to 9.1) ml/kg PBW) vs. males (from median 9.2 [IQR 8.2 to 10.1] to 7.3 [IQR 6.6 to 8.0] ml/kg PBW) (P < .001). In females versus males, use of LTVV increased from 5 to 50% versus from 12 to 78% (difference, -27% [-29% to -25%]; P < .001). The sex difference was mainly driven by patients' body height and actual body weight (adjusted average causal mediation effect, -30% [-33% to -27%]; P < .001, and 4 [3% to 4%]; P < .001).ConclusionsWhile LTVV is increasingly used in females and males, females continue to receive LTVV less often than males. The sex difference is mainly driven by patients' body height and actual body weight, and not necessarily by sex. Use of LTVV in females could improve by paying more attention to a correct calculation of VT, i.e., using the correct body height.
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- 2021
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9. Primeiro datathon brasileiro em terapia intensiva
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Ary Serpa Neto, Guillaume Kugener, Lucas Bulgarelli, Roberto Rabello Filho, Miguel Ángel Armengol de la Hoz, Alistair EW Johnson, Kenneth E Paik, Felipe Torres, Chen Xie, Edson Amaro Júnior, Leonardo José Rolim Ferraz, Leo Anthony Celi, and Rodrigo Octavio Deliberato
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Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Full Text
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