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146 results on '"Rodríguez-Serna, M."'

1. [Translated article] Standard and Expanded Series Patch Testing Update by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC)

Author

Navarro-Triviño, F.J., Borrego, L., Silvestre-Salvador, J.F., Mercader-García, P., Giménez-Arnau, A.M., Ortiz-de Frutos, F.J., Sanz-Sánchez, T., Melé-Ninot, G., Sánchez-Gilo, A., Zaragoza-Ninet, V., Serra-Baldrich, E., Miquel-Miquel, J., Córdoba-Guijarro, S., Rodríguez-Serna, M., Ruíz-González, I., Carrascosa-Carrillo, J.M., Gómez-de la Fuente, E., Pastor-Nieto, M.A., Heras-Mendaza, F., González-Pérez, R., Sánchez-Pedreño Guillén, P., Sánchez-Pérez, J., Gatica-Ortega, M.E., Fernández-Redondo, V., Hervella-Garcés, M., Manrique-Martínez, P., Guimaraens-Juanena, D., García-Gavín, J., Giménez-Arnau, E., Figueras-Nart, I., Curto-Barredo, L., and Armario-Hita, J.C.

Published
2024
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2. Actualización de la batería estándar y batería ampliada de pruebas alérgicas de contacto por el Grupo Español de Investigación en Dermatitis de Contacto y Alergia Cutánea (GEIDAC)

Author

Navarro-Triviño, F.J., Borrego, L., Silvestre-Salvador, J.F., Mercader-García, P., Giménez-Arnau, A.M., Ortiz-de Frutos, F.J., Sanz-Sánchez, T., Melé-Ninot, G., Sánchez-Gilo, A., Zaragoza-Ninet, V., Serra-Baldrich, E., Miquel-Miquel, J., Córdoba-Guijarro, S., Rodríguez-Serna, M., Ruíz-González, I., Carrascosa-Carrillo, J.M., Gómez-de la Fuente, E., Pastor-Nieto, M.A., Heras-Mendaza, F., González-Pérez, R., Sánchez-Pedreño Guillén, P., Sánchez-Pérez, J., Gatica-Ortega, M.E., Fernández-Redondo, V., Hervella-Garcés, M., Manrique-Martínez, P., Guimaraens-Juanena, D., García-Gavín, J., Giménez-Arnau, E., Figueras-Nart, I., Curto-Barredo, L., and Armario-Hita, J.C.

Published
2024
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3. [Translated article] Epidemiological, Clinical, and Allergic Profile of Psoriatic Patients. Evaluation of the Spanish Registry of Contact Dermatitis and Cutaneous Allergy (REIDAC)

Author

Verdaguer-Faja, J., Borrego, L., Mercader-García, P., González Pérez, R., Córdoba-Guijarro, S., Giménez-Arnau, A.M., Ruiz-González, I., Miquel-Miquel, J., Silvestre, J.F., Ortiz de Frutos, F.J., Tous-Romero, F., Sanz Sánchez, T., Rodríguez-Serna, M., Sánchez-Pérez, J., Serra Baldrich, E., Zaragoza-Ninet, V., Pastor-Nieto, M.A., Gática-Ortega, M.E., Sánchez Gilo, A., Melé-Ninot, G., Sánchez-Pedreño Guillén, P., Munera-Campos, M., Descalzo, M.Á., García-Doval, I., and Carrascosa, J.M.

Published
2024
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4. Perfil epidemiológico, clínico y alérgico en pacientes con psoriasis. Evaluación del Registro Español de Dermatitis de Contacto (REIDAC)

Author

Verdaguer-Faja, J., Borrego, L., Mercader-García, P., González Pérez, R., Córdoba-Guijarro, S., Giménez-Arnau, A.M., Ruiz-González, I., Miquel-Miquel, J., Silvestre, J.F., Ortiz de Frutos, F.J., Tous-Romero, F., Sanz Sánchez, T., Rodríguez-Serna, M., Sánchez-Pérez, J., Serra Baldrich, E., Zaragoza-Ninet, V., Pastor-Nieto, M.A., Gática-Ortega, M.E., Sánchez Gilo, A., Melé-Ninot, G., Sánchez-Pedreño Guillén, P., Munera-Campos, M., Descalzo, M.Á., García-Doval, I., and Carrascosa, J.M.

Published
2024
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5. [Translated article] Drug Survival in Cyclosporine Treatment for Moderate to Severe Atopic Dermatitis: Analysis of the Spanish Atopic Dermatitis Registry (BIOBADATOP)

Author

Couselo-Rodríguez, C., Batalla, A., Carrascosa, J.M., Chicharro, P., González-Quesada, A., de la Cueva, P., Giménez-Arnau, A.M., Gilaberte, Y., Rodríguez-Serna, M., Montero-Vilchez, T., Ruiz-Villaverde, R., Elosua-González, M., Silvestre-Salvador, J.F., Munera-Campos, M., Sánchez-Pérez, J., Carretero, G., Mauleón-Fernández, C., Curto-Barredo, L., Ballano-Ruiz, A., Botella-Estrada, R., Arias-Santiago, S., Navarro-Triviño, F.J., Roustan-Gullón, G., Betlloch, I., del Alcázar, E., Abalde-Pintos, M.T., Suárez-Perez, J., García-Doval, I., Descalzo, M.Á., and Flórez, Á.

Published
2024
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6. [Translated article] Four-year Epidemiological Surveillance of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy: Current Situation and Trends

Author

Tous-Romero, F., Borrego-Hernando, L., García-Doval, I., Mercader-García, P., Silvester-Salvador, J.F., Sánchez-Gilo, A., Sanz-Sánchez, T., Giménez-Arnau, A.M., Zaragoza-Ninet, V., Miquel-Miquel, J., González Pérez, R., Córdoba-Guijarro, S., Carrascosa-Carrillo, J.M., Gática-Ortega, M.E., Ruíz-González, I., Serra-Baldrich, E., Pastor-Nieto, A., Rodríguez-Serna, M., Sánchez-Pérez, J., Melé i Ninot, G., Sánchez-Pedreño Guillén, P., and Ortiz-de Frutos, J.

Published
2024
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7. Vigilancia epidemiológica en los últimos 4 años del Registro Español de Investigación en Dermatitis de Contacto y Alergia Cutánea: situación actual y tendencias

Author

Tous-Romero, F., Borrego-Hernando, L., García-Doval, I., Mercader-García, P., Silvester-Salvador, J.F., Sánchez-Gilo, A., Sanz-Sánchez, T., Giménez-Arnau, A.M., Zaragoza-Ninet, V., Miquel-Miquel, J., González Pérez, R., Córdoba-Guijarro, S., Carrascosa-Carrillo, J.M., Gática-Ortega, M.E., Ruíz-González, I., Serra-Baldrich, E., Pastor-Nieto, A., Rodríguez-Serna, M., Sánchez-Pérez, J., Melé i Ninot, G., Sánchez-Pedreño Guillén, P., and Ortiz-de Frutos, J.

Published
2024
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8. Supervivencia de la ciclosporina en el tratamiento de la dermatitis atópica moderada-grave: Registro Español de Dermatitis Atópica (BIOBADATOP)

Author

Couselo-Rodríguez, C., Batalla, A., Carrascosa, J.M., Chicharro, P., González-Quesada, A., de la Cueva, P., Giménez-Arnau, A.M., Gilaberte, Y., Rodríguez-Serna, M., Montero-Vilchez, T., Ruiz-Villaverde, R., Elosua-González, M., Silvestre-Salvador, J.F., Munera-Campos, M., Sánchez-Pérez, J., Carretero, G., Mauleón-Fernández, C., Curto-Barredo, L., Ballano-Ruiz, A., Botella-Estrada, R., Arias-Santiago, S., Navarro-Triviño, F.J., Roustan-Gullón, G., Betlloch, I., del Alcázar, E., Abalde-Pintos, M.T., Suárez-Perez, J., García-Doval, I., Descalzo, M.Á., and Flórez, Á.

Published
2024
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11. Candidate allergens for inclusion in the Spanish Standard Series based on data from the Spanish Contact Dermatitis Registry

Author

Hernández-Fernández, C.P., Mercader-García, P., Silvestre Salvador, J.F., Sánchez Pérez, J., Fernández Redondo, V., Miquel Miquel, F.J., Ortiz de Frutos, F.J., Gatica Ortega, M.E., Mora Fernández, V., Giménez Arnau, A.M., Zaragoza Ninet, V., González Pérez, R., Sanz Sánchez, T., Pastor Nieto, M.A., Serra Baldrich, E., Córdoba Guijarro, S., Heras Mendaza, F., Ruiz González, I., Rodríguez Serna, M., Hervella Garcés, M., Gallego Descalzo, M.A., García Doval, I., and Borrego Hernando, L.

Published
2021
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12. Allergic contact dermatitis in adults with and without atopic dermatitis: Evaluation of the Spanish Contact Dermatitis Registry (REIDAC).

Author

Chicharro, P., Munera‐Campos, M., Zaragoza‐Ninet, V., Giménez‐Arnau, A., González‐Pérez, R., Miquel‐Miquel, F. J., Córdoba‐Guijarro, S., Sanz‐Sánchez, T., Ruiz‐González, I., Silvestre‐Salvador, J. F., Serra‐Baldrich, E., Borrego, L., Pastor‐Nieto, M. A., Ortiz de Frutos, F. J., Mercader‐García, P., Heras‐Mendaza, F., Fernández‐Redondo, V., Rodríguez‐Serna, M., Hervella‐García, M., and Carrascosa, J. M.

Subjects
ATOPIC dermatitis, NICKEL sulfate, CONTACT dermatitis, COBALT chloride, ALLERGENS
Abstract

Background: Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are inflammatory skin conditions whose association is not clearly defined. Objectives: To identify differences in ACD profile between patients with and without AD among those referred for patch testing. Additionally, to determine the prevalence of sensitisation to standard Spanish contact allergens in both groups. Methods: We analysed two groups (AD and non‐AD) within the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy (REIDAC). Contact allergy, clinical relevance and epidemiological data were compared between them. Results: A total of 5055 patients were included. Among them, 23% (1168) had a history or final diagnosis of AD. At least one positive reaction was seen in 468 (40%) of AD patients and 1864 (48%) of non‐AD patients. In both groups, the most common positive reactions were to nickel sulphate, methylchloroisothiazolinone/methylisothiazolinone and cobalt chloride. Age‐adjusted OR for sensitisation to nickel sulphate was 0.72 (95% CI: 0.61–0.86), indicating a decreased likelihood of sensitisation in AD patients compared to non‐AD individuals. Conclusions: We did not find an increased presence of ACD in patients with AD referred for patch testing, exhibiting similar profiles to non‐AD population, except for a negative relationship between AD and sensitisation to nickel sulphate. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Vigilancia epidemiológica en los últimos 4 años del Registro Español de Investigación en Dermatitis de Contacto y Alergia Cutánea: situación actual y tendencias

Author

Tous-Romero, F., primary, Borrego-Hernando, L., additional, García-Doval, I., additional, Mercader-García, P., additional, Silvester-Salvador, J.F., additional, Sánchez-Gilo, A., additional, Sanz-Sánchez, T., additional, Giménez-Arnau, A.M., additional, Zaragoza-Ninet, V., additional, Miquel-Miquel, J., additional, González Pérez, R., additional, Córdoba-Guijarro, S., additional, Carrascosa-Carrillo, J.M., additional, Gática-Ortega, M.E., additional, Ruíz-González, I., additional, Serra-Baldrich, E., additional, Pastor-Nieto, A., additional, Rodríguez-Serna, M., additional, Sánchez-Pérez, J., additional, Melé i Ninot, G., additional, Sánchez-Pedreño Guillén, P., additional, and Ortiz-de Frutos, J., additional

Published
2023
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20. BIOBADATOP: Registro Español de Dermatitis Atópica. Descripción y primeros resultados

Author

Munera-Campos, M., primary, Chicharro, P., additional, Gonzalez Quesada, A., additional, Florez Menendez, A., additional, de la Cueva Dovao, P., additional, Gimenez Arnau, AM., additional, Gilaberte Calzada, Y., additional, Rodríguez Serna, M., additional, Montero, T., additional, Silvestre Salvador, JF., additional, Elosua González, M., additional, del Alcazar, E., additional, Santamaría, C., additional, Sánchez-Pérez, J., additional, Carretero Hernández, G., additional, Batalla Cebey, A., additional, Jin Suh Oh, H., additional, Mauleón Fernández, C., additional, Curto Barredo, L., additional, Bertolín, M., additional, Navarro Bielsa, A., additional, Ballano Ruiz, A., additional, Botella Estrada, R., additional, Arias Santiago, S., additional, Betlloch, I., additional, Roustan Gullón, G., additional, Rosell Díaz, A., additional, Descalzo, MÁ., additional, García-Doval, I., additional, and Carrascosa, JM., additional

Published
2023
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21. Dupilumab for atopic dermatitis during pregnancy and breastfeeding: Clinical experience in 13 patients.

Author

Escolà, H., Figueras‐Nart, I., Bonfill‐Orti, M., Coll Puigserver, N., Martin‐Santiago, A., Rodríguez Serna, M., Sánchez Hernández, M. C., Sanz‐Cabanillas, J. L., Taberner, R., Zaragoza‐Ninet, V., Pujol, R. M., and Curto‐Barredo, L.

Subjects
ATOPIC dermatitis, DUPILUMAB, PREGNANCY, ANKYLOGLOSSIA, BREASTFEEDING, PATIENTS' attitudes
Abstract

Patients' characteristics, treatments received before dupilumab, reasons that led to initiate this treatment as well as the cause of treatment discontinuation are mentioned in Table 1. Duration of 9 month during pregnancy and 1 month during breastfeeding-Patient 123425CaucasianAsthmaTopical and systemic corticosteroids, cyclosporineUnknownBefore pregnancyShared decision-making was adopted after a risk-benefit assessment, discussing the course of AD, safety data, potential therapeutic options and previous response to systemic treatmentsLeft the treatment. [Extracted from the article]

Published
2023
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22. Perfil epidemiológico, clínico, y alérgico en pacientes con dermatitis atópica y dermatitis de las manos. Evaluación del Registro Español de Dermatitis de Contacto (REIDAC

Author

Dermatología, oftalmología y otorrinolaringología, Dermatologia, oftalmologia eta otorrinolaringologia, Mora-Fernández, V., Mercader Garcia, P., Borrego Hernando, L., González Pérez, Ricardo, Córdoba Guijarro, S., Giménez Arnau, A., Ruiz González, I., Miquel Miquel, F.J., Silvestre Salvador, J.F., Ortiz de Frutos, F.J., Sanz Sanchez, T., Rodríguez Serna, M., Fernández Redondo, V., Sanchez Perez, J., Heras Mendaza, F., Serra Baldrich, E, Zaragoza Ninet, V., Pastor Nieto, M.A., Hervella Garcia, M., Garcia Doval, I., Carrascosa, J.M., Dermatología, oftalmología y otorrinolaringología, Dermatologia, oftalmologia eta otorrinolaringologia, Mora-Fernández, V., Mercader Garcia, P., Borrego Hernando, L., González Pérez, Ricardo, Córdoba Guijarro, S., Giménez Arnau, A., Ruiz González, I., Miquel Miquel, F.J., Silvestre Salvador, J.F., Ortiz de Frutos, F.J., Sanz Sanchez, T., Rodríguez Serna, M., Fernández Redondo, V., Sanchez Perez, J., Heras Mendaza, F., Serra Baldrich, E, Zaragoza Ninet, V., Pastor Nieto, M.A., Hervella Garcia, M., Garcia Doval, I., and Carrascosa, J.M.

Abstract

BACKGROUND: Hand eczema is common in patients with atopic dermatitis (AD), but few studies have described the characteristics of these patients in large, representative populations from different geographic regions and occupational settings. OBJECTIVE: To describe the epidemiological, clinical, and allergy profile of patients with hand eczema who underwent patch testing and compare patients with and without AD. METHODS: Analysis of data from the Spanish Contact Dermatitis Registry, a multicenter registry of patients who undergo patch testing in Spain. RESULTS: We included 1466 patients with hand eczema who were patch tested between January 2018 and June 2020. Those with AD were younger and had had symptoms for longer before testing. They were also more likely to have been exposed to occupational triggers (38% vs 53% for patients without AD). The only profession for which significant differences were found was hairdressing. The most common allergens were nickel sulfate, methylchloroisothiazolinone/methylisothiazolinone, cobalt chloride, potassium dichromate, fragrance mixes I and II, and formaldehyde. The most common diagnoses were allergic contact dermatitis (24% vs 31% in patients with and without AD, P=.0224) and irritant contact dermatitis (18% and 35% respectively, P<.001). CONCLUSIONS: AD is common in patients with predominant hand eczema who undergo patch testing. Patients with hand eczema and AD have different clinical and epidemiological characteristics to hand eczema patients in general and their final diagnosis following patch testing is also different.

Published
2022

23. Contact sensitization to limonene and linalool hydroperoxides in Spain: a GEIDAC* prospective study

Author

Deza, Gustavo, García‐Bravo, Begoña, Silvestre, Juan F., Pastor‐Nieto, Maria A., González‐Pérez, Ricardo, Heras‐Mendaza, Felipe, Mercader, Pedro, Fernández‐Redondo, Virginia, Niklasson, Bo, Giménez‐Arnau, Ana M., Hita, J. Armario, Hernando, L. Borrego, Carrillo, J. Carrascosa, Guijarro, S. Córdoba, Gavín, J. García, Ortega, M. Gattica, de la Fuente, J. Gómez, Hervella Garcés, M., de Frutos, J. Ortiz, Rodríguez Serna, M., Ruíz González, I., Sánchez Pedreño, P., Sánchez Pérez, J., and Baldrich, E. Serra

Published
2017
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24. [Translated article] Epidemiological, Clinical, and Allergy Profile of Patients With Atopic Dermatitis and Hand Eczema: Evaluation of the Spanish Contact Dermatitis Registry (REIDAC)

Author

Mora-Fernández, V., primary, Mercader Garcia, P., additional, Borrego Hernando, L., additional, González Pérez, R., additional, Córdoba Guijarro, S., additional, Giménez Arnau, A., additional, Ruiz González, I., additional, Miquel Miquel, F.J., additional, Silvestre Salvador, J.F., additional, Ortiz de Frutos, F.J., additional, Sanz Sanchez, T., additional, Rodríguez Serna, M., additional, Fernández Redondo, V., additional, Sanchez Perez, J., additional, Heras Mendaza, F., additional, Serra Baldrich, E., additional, Zaragoza Ninet, V., additional, Pastor Nieto, M.A., additional, Hervella Garcia, M., additional, Garcia Doval, I., additional, and Carrascosa, J.M., additional

Published
2022
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25. Perfil epidemiológico, clínico, y alérgico en pacientes con dermatitis atópica y dermatitis de las manos. Evaluación del Registro Español de Dermatitis de Contacto (REIDAC)

Author

Mora-Fernández, V., primary, Mercader Garcia, P., additional, Borrego Hernando, L., additional, González Pérez, R., additional, Córdoba Guijarro, S., additional, Giménez Arnau, A., additional, Ruiz González, I., additional, Miquel Miquel, F.J., additional, Silvestre Salvador, J.F., additional, Ortiz de Frutos, F.J., additional, Sanz Sanchez, T., additional, Rodríguez Serna, M., additional, Fernández Redondo, V., additional, Sanchez Perez, J., additional, Heras Mendaza, F., additional, Serra Baldrich, E., additional, Zaragoza Ninet, V., additional, Pastor Nieto, M.A., additional, Hervella Garcia, M., additional, Garcia Doval, I., additional, and Carrascosa, J.M., additional

Published
2022
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27. Alérgenos candidatos para ser incluidos en la serie estándar española a partir de los datos del Registro Español de Dermatitis de Contacto

Author

Hernández-Fernández, C.P., primary, Mercader-García, P., additional, Silvestre Salvador, J.F., additional, Sánchez Pérez, J., additional, Fernández Redondo, V., additional, Miquel Miquel, F.J., additional, Ortiz de Frutos, F.J., additional, Gatica Ortega, M.E., additional, Mora Fernández, V., additional, Giménez Arnau, A.M., additional, Zaragoza Ninet, V., additional, González Pérez, R., additional, Sanz Sánchez, T., additional, Pastor Nieto, M.A., additional, Serra Baldrich, E., additional, Córdoba Guijarro, S., additional, Heras Mendaza, F., additional, Ruiz González, I., additional, Rodríguez Serna, M., additional, Hervella Garcés, M., additional, Gallego Descalzo, M.Á., additional, García Doval, I., additional, and Borrego Hernando, L., additional

Published
2021
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30. Patch testing with formaldehyde 2% aq. - A multicenter study in Spain

Author

Sanz-Sánchez T, Mercader García P, Silvestre Salvador JF, Heras Mendaza F, Gatica Ortega ME, González Pérez R, Zaragoza Ninet V, Rodríguez Serna M, Hervella Garcés M, Córdoba Guijarro S, Fernandez Redondo V, Borrego L, Sánchez-Pedreño P, and Giménez Arnau AM

Subjects
allergic contact dermatitis, formaldehyde, patch test
Published
2019

35. Towards Personalized Medicine in Melanoma: Implementation of a Clinical Next-Generation Sequencing Panel

Author

de Unamuno Bustos B, Murria Estal R, Pérez Simó G, de Juan Jimenez I, Escutia Muñoz B, Rodríguez Serna M, Alegre de Miquel V, Llavador Ros M, Ballester Sánchez R, Nagore Enguídanos E, Palanca Suela S, and Botella Estrada R

Abstract

Molecular diagnostics are increasingly performed routinely in the diagnosis and management of patients with melanoma due to the development of novel therapies that target specific genetic mutations. The development of next-generation sequencing (NGS) technologies has enabled to sequence multiple cancer-driving genes in a single assay, with improved sensitivity in mutation detection. The main objective of this study was the design and implementation of a melanoma-specific sequencing panel, and the identification of the spectrum of somatic mutations in a series of primary melanoma samples. A custom panel was designed to cover the coding regions of 35 melanoma-related genes. Panel average coverage was 2,575.5 reads per amplicon, with 92,8% of targeted bases covered >= 500x. Deep coverage enabled sensitive discovery of mutations in as low as 0.5% mutant allele frequency. Eighty-five percent (85/100) of the melanomas had at least one somatic mutation. The most prevalent mutated genes were BRAF (50%; 50/199), NRAS (15%; 15/100), PREX2 (14%; 14/100), GRIN2A (13%; 13/100), and ERBB4 (12%; 12/100). Turn-around-time and costs for NGS-based analysis was reduced in comparison to conventional molecular approaches. The results of this study demonstrate the cost-effectiveness and feasibility of a custom-designed targeted NGS panel, and suggest the implementation of targeted NGS into daily routine practice.

Published
2017

39. Contact sensitization to limonene and linalool hydroperoxides in Spain: a GEIDAC* prospective study.

Author

Deza, Gustavo, García ‐ Bravo, Begoña, Silvestre, Juan F., Pastor ‐ Nieto, Maria A., González ‐ Pérez, Ricardo, Heras ‐ Mendaza, Felipe, Mercader, Pedro, Fernández ‐ Redondo, Virginia, Niklasson, Bo, Giménez ‐ Arnau, Ana M., Hita, J. Armario, Hernando, L. Borrego, Carrillo, J. Carrascosa, Guijarro, S. Córdoba, Gavín, J. García, Ortega, M. Gattica, de la Fuente, J. Gómez, Hervella Garcés, M., de Frutos, J. Ortiz, and Rodríguez Serna, M.

Subjects
LIMONENE, ALLERGIES, LINALOOL, HYDROPEROXIDES, CONTACT dermatitis, ODORS
Abstract

Background Limonene and linalool are common fragrance terpenes widely used in cosmetic, household and hygiene products. Their primary oxidation products formed after air exposure, the hydroperoxides, have been recognized as important contact haptens. Objectives To investigate the prevalence of contact allergy to hydroperoxides of limonene (Lim-OOHs) and hydroperoxides of linalool (Lin-OOHs) in Spain, and to define the optimal concentration for screening in consecutive patients. Methods Three different concentrations of Lim-OOHs (0.1%, 0.2% and 0.3% pet.) and Lin-OOHs (0.25%, 0.5% and 1.0% pet.) were simultaneously tested in 3639 consecutive patients at 22 departments of dermatology in Spain. Results Lim-OOHs at 0.1%, 0.2% and 0.3% yielded positive patch test reactions in 1.4%, 3.4% and 5.1% of the tested patients, respectively; and Lin-OOHs at 0.25%, 0.5% and 1.0% yielded positive reactions in 1.3%, 2.9% and 4.9% of the tested patients, respectively. Few irritant (1.5-1.9%) and doubtful reactions (0.4-0.5%) to both terpene hydroperoxides were registered at the highest concentrations tested. Conclusions Lim-OOHs and Lin-OOHs can be considered as common causes of contact allergy, and their inclusion in an extended baseline patch test series therefore seems to be appropriate. The patch test preparations of Lim-OOHs 0.3% pet. and Lin-OOHs 1.0% pet. are useful tools for screening of contact sensitization. [ABSTRACT FROM AUTHOR]

Published
2017
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43. [Translated article] BIOBADATOP Spanish Atopic Dermatitis Registry: Description and Early Findings

Author

Munera-Campos, M., Chicharro, P., Gonzalez Quesada, A., Flórez Menéndez, Á., de la Cueva Dobao, P., Gimenez Arnau, A.M., Gilaberte Calzada, Y., Rodríguez Serna, M., Montero-Vilchez, T., Silvestre, J.F., Elosua-González, M., del Alcázar, E., Santamaría, C., Sánchez-Pérez, J., Carretero Hernández, G., Batalla, A., Jin Suh Oh, H., Mauleón Fernández, C., Curto Barredo, L., Bertolín-Colilla, M., Navarro Bielsa, A., Ballano Ruiz, A., Botella Estrada, R., Arias Santiago, S., Betlloch, I., Roustan Gullón, G., Rosell Díaz, A., Descalzo, M.A., García-Doval, I., and Carrascosa, J.M.

Abstract

[Display omitted]

Published
2023
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48. Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023.

Author

Pesqué D, Planella-Fontanillas N, Borrego L, Sanz-Sánchez T, Zaragoza-Ninet V, Serra-Baldrich E, Miquel-Miquel FJ, Silvestre-Salvador JF, Córdoba-Guijarro S, Sánchez-Gilo A, Mercader-García P, Navarro-Triviño FJ, Ortiz-de-Frutos FJ, Tous-Romero F, Rodríguez-Serna M, Melé-Ninot G, Barrabés-Torrella C, Ruiz-González I, Pastor-Nieto MA, Carrascosa-Carrillo JM, Gómez-de-la-Fuente E, Sánchez-Pedreño-Guillén P, Sánchez-Pérez J, Pereyra-Rodríguez JJ, Gatica-Ortega ME, González-Pérez R, Pujol RM, Descalzo MÁG, García-Doval I, and Giménez-Arnau AM

Abstract

Introduction: Patch test results may be influenced by age-related factors. However, there is still discordant evidence between age and patch test results., Objectives: We aim to evaluate the patch test results reflecting skin sensitisation, their relevance and association with clinical features by age group., Methods: Prospective multicentric study of all patients patch tested with the Spanish baseline series in participating centres. Age groups were pre-defined as children (0- to 11-years), adolescents (12- to 18-years), young adults (19- to 30-years), middle-aged adults (31- to 65-years) and older adults (≥66-years). Occurrence of sensitisation, relevance and clinical features were compared by age group. Factors associated with skin sensitisation were investigated with multivariate logistic regression., Results: A total of 13 368 patients were patch-tested. Differences in positive patch test results and relevance by age were detected with the highest proportion in middle-aged adults. Age-related trend differences were found for nickel, potassium dichromate, caines, colophony, Myroxylon pereirae resin, 2-hydroxyethyl methacrylate and limonene hydroperoxide. The multivariate logistic analysis (adjusted for sex, atopic dermatitis, body location and occupational dermatitis) showed an association between the age group of 31-65 (OR: 1.41, 95% CI: 1.26-1.58) and above 66-years (OR: 1.15, 95% CI: 1.01-1.32) with a higher proportion of positive results, compared with young adults., Conclusions: Positive patch test results vary according to age, with the highest occurrence in middle-aged adults. Most haptens did not present age-related differences, reinforcing the use of baseline series regardless of age., (© 2024 The Author(s). Contact Dermatitis published by John Wiley & Sons Ltd.)

Published
2024
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