Search

Your search keyword '"Rodríguez-Castro, Emilio"' showing total 35 results
Start Over Author "Rodríguez-Castro, Emilio"
35 results on '"Rodríguez-Castro, Emilio"'

1. Effect of early vs. delayed extubation on functional outcome among patients with acute ischemic stroke treated with endovascular thrombectomy under general anesthesia: the prospective, randomized controlled EDESTROKE trial study protocol

Author

Taboada, Manuel, Estany-Gestal, Ana, Fernández, Jorge, Barreiro, Laura, Williams, Kora, Rodríguez-Yáñez, Manuel, Otero, Pablo, Naveira, Alberto, Caruezo, Valentín, Veiras, Sonia, San Luis, Eva, Dos Santos, Laura, Diaz-Vieito, María, Arias-Rivas, Susana, Santamaría-Cadavid, María, Rodríguez-Castro, Emilio, Vázquez, Fernando, Blanco, Miguel, Mosquera, Antonio, Castiñeiras, Jose Antonio, Muniategui, Ignacio, Ferreiroa, Esteban, Cariñena, Agustín, Tubio, Ana, Campaña, Olga, Selas, Salomé, Aneiros, Francisco, Martínez, Adrián, Eiras, María, Costa, Jose, Prieto, Jose María, and Álvarez, Julián

Published
2024
Full Text
View/download PDF

2. Carotid web: the challenging diagnosis of an under-recognized entity

Author

Rodríguez-Castro, Emilio, Arias-Rivas, Susana, Santamaría-Cadavid, María, López-Dequidt, Iria, Rodríguez-Yáñez, Manuel, Mosqueira, Antonio Jesús, Blanco Ulla, Miguel, Vázquez Herrero, Fernando, Castiñeira, José Antonio, Martínez-Sáez, Elena, Pérez Béliz, Edurne, Mosquera, Nilo, Caicedo, Diego, Fraga, Máximo, and Pumar, José Manuel

Published
2022
Full Text
View/download PDF

3. Resultados de un programa de ecocardioscopia realizada por neurólogos en el proceso integrado en red de atención al ictus en unidades de imagen cardiaca

Author

López-Dequidt, Iria, Martínez-Monzonis, Amparo, Peña-Gil, Carlos, González-Maestro, Adrián, González-Salvado, Violeta, Rodríguez-Castro, Emilio, Santamaría-Cadavid, María, Arias-Rivas, Susana, Rodríguez-Yáñez, Manuel, Prieto González, José María, and González-Juanatey, José Ramón

Published
2023
Full Text
View/download PDF

6. Early Neurological Change After Ischemic Stroke Is Associated With 90-Day Outcome

Author

Heitsch, Laura, Ibanez, Laura, Carrera, Caty, Binkley, Michael M., Strbian, Daniel, Tatlisumak, Turgut, Bustamante, Alejandro, Ribó, Marc, Molina, Carlos, Dávalos, Antoni, López-Cancio, Elena, Muñoz-Narbona, Lucia, Soriano-Tárraga, Carol, Giralt-Steinhauer, Eva, Obach, Victor, Slowik, Agnieszka, Pera, Joanna, Lapicka-Bodzioch, Katarzyna, Derbisz, Justyna, Sobrino, Tomás, Castillo, José, Campos, Francisco, Rodríguez-Castro, Emilio, Arias-Rivas, Susana, Segura, Tomas, Serrano-Heras, Gemma, Vives-Bauza, Cristófol, Díaz-Navarro, Rosa, Tur, Silva, Jimenez, Carmen, Martí-Fàbregas, Joan, Delgado-Mederos, Raquel, Arenillas, Juan, Krupinski, Jerzy, Cullell, Natalia, Torres-Aguila, Nuria P., Muiño, Elena, Cárcel-Márquez, Jara, Moniche, Francisco, Cabezas, Juan A., Ford, Andria L., Dhar, Rajat, Roquer, Jaume, Khatri, Pooja, Jiménez-Conde, Jordi, Fernandez-Cadenas, Israel, Montaner, Joan, Rosand, Jonathan, Cruchaga, Carlos, and Lee, Jin-Moo

Published
2021
Full Text
View/download PDF

11. Results of a focused cardiac ultrasound program conducted by neurologists within a stroke care network with cardiac imaging units

Author

López-Dequidt, Iria, primary, Martínez-Monzonis, Amparo, additional, Peña-Gil, Carlos, additional, González-Maestro, Adrián, additional, González-Salvado, Violeta, additional, Rodríguez-Castro, Emilio, additional, Santamaría-Cadavid, María, additional, Arias-Rivas, Susana, additional, Rodríguez-Yáñez, Manuel, additional, Prieto González, José María, additional, and González-Juanatey, José Ramón, additional

Published
2023
Full Text
View/download PDF

13. Trends in stroke outcomes in the last ten years in a European tertiary hospital

Author

Rodríguez-Castro, Emilio, López-Dequit, Iria, Santamaría-Cadavid, María, Arias-Rivas, Susana, Rodríguez-Yáñez, Manuel, Pumar, José Manuel, Hervella, Pablo, López-Arias, Esteban, da Silva-Candal, Andrés, Estany, Ana, Piñeiro-Lamas, María, Sobrino, Tomás, Campos, Francisco, Portela, Manuel, Vázquez-Lima, Manuel, Castillo, José, and Iglesias-Rey, Ramón

Published
2018
Full Text
View/download PDF

15. RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis

Author

Muiño, Elena, primary, Cárcel-Márquez, Jara, additional, Carrera, Caty, additional, Llucià-Carol, Laia, additional, Gallego-Fabrega, Cristina, additional, Cullell, Natalia, additional, Lledós, Miquel, additional, Castillo, José, additional, Sobrino, Tomás, additional, Campos, Francisco, additional, Rodríguez-Castro, Emilio, additional, Millán, Mònica, additional, Muñoz-Narbona, Lucía, additional, Bustamante, Alejandro, additional, López-Cancio, Elena, additional, Ribó, Marc, additional, Álvarez-Sabín, José, additional, Jiménez-Conde, Jordi, additional, Roquer, Jaume, additional, Giralt-Steinhauer, Eva, additional, Soriano-Tárraga, Carolina, additional, Vives-Bauza, Cristófol, additional, Díaz-Navarro, Rosa, additional, Tur, Silvia, additional, Obach, Victor, additional, Arenillas, Juan, additional, Segura, Tomás, additional, Serrano-Heras, Gemma, additional, Martí-Fàbregas, Joan, additional, Delgado-Mederos, Raquel, additional, Camps-Renom, Pol, additional, Prats-Sánchez, Luis, additional, Guisado, Daniel, additional, Guasch, Marina, additional, Marin, Rebeca, additional, Martínez-Domeño, Alejandro, additional, Freijo-Guerrero, Maria, additional, Moniche, Francisco, additional, Cabezas, Juan, additional, Castellanos, Mar, additional, Krupinsky, Jerzy, additional, Strbian, Daniel, additional, Tatlisumak, Turgut, additional, Thijs, Vincent, additional, Lemmens, Robin, additional, Slowik, Agnieszka, additional, Pera, Joanna, additional, Heitsch, Laura, additional, Ibañez, Laura, additional, Cruchaga, Carlos, additional, Dhar, Rajat, additional, Lee, Jin-Moo, additional, Montaner, Joan, additional, Fernández-Cadenas, Israel, additional, Consortium, on, additional, and Consortium, the, additional

Published
2021
Full Text
View/download PDF

16. Obesity-related genetic determinants of stroke

Author

Gago-Dominguez, Manuela, primary, Sobrino, Tomás, additional, Torres-Español, María, additional, Calaza, Manuel, additional, Rodríguez-Castro, Emilio, additional, Campos, Francisco, additional, Redondo, Carmen M, additional, Castillo, José, additional, and Carracedo, Ángel, additional

Published
2021
Full Text
View/download PDF

17. Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma

Author

Carrera, Caty, primary, Cárcel-Márquez, Jara, additional, Cullell, Natalia, additional, Torres-Águila, Nuria, additional, Muiño, Elena, additional, Castillo, José, additional, Sobrino, Tomás, additional, Campos, Francisco, additional, Rodríguez-Castro, Emilio, additional, Llucià-Carol, Laia, additional, Millán, Mònica, additional, Muñoz-Narbona, Lucía, additional, López-Cancio, Elena, additional, Bustamante, Alejandro, additional, Ribó, Marc, additional, Álvarez-Sabín, José, additional, Jiménez-Conde, Jordi, additional, Roquer, Jaume, additional, Giralt-Steinhauer, Eva, additional, Soriano-Tárraga, Carolina, additional, Mola-Caminal, Marina, additional, Vives-Bauza, Cristófol, additional, Navarro, Rosa Díaz, additional, Tur, Silvia, additional, Obach, Victor, additional, Arenillas, Juan Francisco, additional, Segura, Tomás, additional, Serrano-Heras, Gemma, additional, Martí-Fàbregas, Joan, additional, Delgado-Mederos, Raquel, additional, Freijo-Guerrero, M Mar, additional, Moniche, Francisco, additional, Cabezas, Juan Antonio, additional, Castellanos, Mar, additional, Gallego-Fabrega, Cristina, additional, González-Sanchez, Jonathan, additional, Krupinsky, Jurek, additional, Strbian, Daniel, additional, Tatlisumak, Turgut, additional, Thijs, Vincent, additional, Lemmens, Robin, additional, Slowik, Agnieszka, additional, Pera, Johanna, additional, Kittner, Steven, additional, Cole, John, additional, Heitsch, Laura, additional, Ibañez, Laura, additional, Cruchaga, Carlos, additional, Lee, Jin-Moo, additional, Montaner, Joan, additional, and Fernández-Cadenas, Israel, additional

Published
2021
Full Text
View/download PDF

18. Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain

Author

Tejada Meza, Herbert, Lambea Gil, Álvaro, Sancho Saldaña, Agustín, Martínez-Zabaleta, Maite, de la Riva, Patricia, López-Cancio Martínez, Elena, Castañón Apilánez, María, Herrera Isasi, María, Marta Enguita, Juan, Lera Alfonso, Mercedes de, Arenillas, Juan, Segurola Olaizaola, Jon, Timiraos Fernández, Juan José, Sánchez, Joaquín, Castellanos, María del Mar, Roel, Alexia, Casado Menéndez, Ignacio, Freijo Guerrero, María del Mar, Luna, Alain, Palacio-Portilla, Enrique Jesús, Jiménez López, Yésica, Rodríguez Castro, Emilio, Arias Rivas, Susana, Tejada García, Javier, Beltrán Rodríguez, Iria, Julián Villaverde, Francisco, Moreno García, María Pilar, Trejo-Gabriel-Galán, José María, Echevarría Íñiguez, Ana, Tejero Juste, Carlos, Pérez Lázaro, Cristina, Marta Moreno, Javier, Tejada Meza, Herbert, Lambea Gil, Álvaro, Sancho Saldaña, Agustín, Martínez-Zabaleta, Maite, de la Riva, Patricia, López-Cancio Martínez, Elena, Castañón Apilánez, María, Herrera Isasi, María, Marta Enguita, Juan, Lera Alfonso, Mercedes de, Arenillas, Juan, Segurola Olaizaola, Jon, Timiraos Fernández, Juan José, Sánchez, Joaquín, Castellanos, María del Mar, Roel, Alexia, Casado Menéndez, Ignacio, Freijo Guerrero, María del Mar, Luna, Alain, Palacio-Portilla, Enrique Jesús, Jiménez López, Yésica, Rodríguez Castro, Emilio, Arias Rivas, Susana, Tejada García, Javier, Beltrán Rodríguez, Iria, Julián Villaverde, Francisco, Moreno García, María Pilar, Trejo-Gabriel-Galán, José María, Echevarría Íñiguez, Ana, Tejero Juste, Carlos, Pérez Lázaro, Cristina, and Marta Moreno, Javier

Abstract

[Abstract] Background and purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain. Methods: Spanish multicenter retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. We recorded the number of patients admitted for ischemic stroke between 30 December 2019 and 3 May 2020, the number of IVT and EVT procedures, and in-hospital mortality. Results: In the study period, 2737 patients were admitted with ischemic stroke. There was a decrease in the weekly mean admitted patients during the pandemic (124 vs. 173, p<0.001). In-hospital mortality of stroke patients increased significantly (9.9% vs. 6.5%, p = 0.003), but there were no differences in the proportion of IVT (17.3% vs. 16.1%, p = 0.405) or EVT (22% vs. 23%, p = 0.504). Conclusion: We found a decrease in the number of ischemic stroke admissions and an increase in in-hospital mortality during the COVID-19 epidemic in this large study from North-West Spain. There were regional changes within the network, not fully explained by the severity of the pandemic in different regions.

Published
2020

19. Impact of COVID‐19 outbreak in reperfusion therapies of acute ischemic stroke in North‐West Spain

Author

Tejada Meza, Herbert [0000-0002-6506-1037], Lambea-Gil, Álvaro [0000-0003-1785-9201], Navarro Pérez, María Pilar [0000-0001-6370-218X], Tejada Meza, Herbert, Lambea-Gil, Álvaro, Sancho Saldaña, Agustín, Martínez-Zabaleta, Maite, Garmendia Lopetegui, Eñaut, López-Cancio, Elena, Castañón Apilánez, María, Herrera Isasi, María, Marta Enguita, Juan, Gómez-Vicente, Beatriz, Arenillas, Juan F., Arenaza Basterrechea, Naroa, Timiraos Fernández, Juan José, Sánchez, Joaquín, Maciñeiras Montero, José Luis, Castellanos-Rodrigo, Mar, Fernández‐Coud, Dolores, Casado Menéndez, Ignacio, Temprano Fernández, María Teresa, Freijo, Mar, Luna, Alain, Palacio Portilla, Enrique, Jiménez López, Yésica, Rodríguez Castro, Emilio, Rodríguez‐Yáñez, Manuel, Tejada García, Javier, Beltrán Rodríguez, Iria, Julián-Villaverde, Francisco, Moreno García, María Pilar, Trejo-Gabriel-Galán, José María, Echavarría Iñiguez, Ana, Pérez Lázaro, Cristina, Navarro Pérez, María Pilar, Marta Moreno, Javier, Tejada Meza, Herbert [0000-0002-6506-1037], Lambea-Gil, Álvaro [0000-0003-1785-9201], Navarro Pérez, María Pilar [0000-0001-6370-218X], Tejada Meza, Herbert, Lambea-Gil, Álvaro, Sancho Saldaña, Agustín, Martínez-Zabaleta, Maite, Garmendia Lopetegui, Eñaut, López-Cancio, Elena, Castañón Apilánez, María, Herrera Isasi, María, Marta Enguita, Juan, Gómez-Vicente, Beatriz, Arenillas, Juan F., Arenaza Basterrechea, Naroa, Timiraos Fernández, Juan José, Sánchez, Joaquín, Maciñeiras Montero, José Luis, Castellanos-Rodrigo, Mar, Fernández‐Coud, Dolores, Casado Menéndez, Ignacio, Temprano Fernández, María Teresa, Freijo, Mar, Luna, Alain, Palacio Portilla, Enrique, Jiménez López, Yésica, Rodríguez Castro, Emilio, Rodríguez‐Yáñez, Manuel, Tejada García, Javier, Beltrán Rodríguez, Iria, Julián-Villaverde, Francisco, Moreno García, María Pilar, Trejo-Gabriel-Galán, José María, Echavarría Iñiguez, Ana, Pérez Lázaro, Cristina, Navarro Pérez, María Pilar, and Marta Moreno, Javier

Abstract

Since the first reported case in early December 2019, severe acute respiratory coronavirus 2 (SARS‐CoV‐2) infection, known as Coronavirus Disease 2019 (COVID‐19), has spread all over the world (1‐3). As of June 4th, more than 6 million cases and 350,000 deaths have been reported worldwide (4). Treating these patients and containing the outbreak has become the main priority in any center, arising the risk of possible collateral damage on patients with other acute diseases due to the collapse of the pre‐ and intra‐hospital emergency care systems.

Published
2020

20. Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain

Author

Tejada Meza, Herbert [0000-0002-6506-1037], Lambea-Gil, Álvaro [0000-0003-1785-9201], Arenillas, Juan F. [0000-0001-7464-6101], Trejo-Gabriel-Galán, José María [0000-0001-9591-8452], Tejada Meza, Herbert, Lambea-Gil, Álvaro, Sancho Saldaña, Agustín, Martínez-Zabaleta, Maite, Riva Juez, Patricia de la, López-Cancio, Elena, Castañón Apilánez, María, Herrera Isasi, María, Marta Enguita, Juan, Lera Alfonso, Mercedes de, Arenillas, Juan F., Segurola Olaizola, Jon, Timiraos Fernández, Juan José, Sánchez, Joaquín, Castellanos-Rodrigo, Mar, Roel, Alexia, Casado Menéndez, Ignacio, Freijo, Mar, Luna, Alain, Palacio Portilla, Enrique, Jiménez López, Yésica, Rodríguez Castro, Emilio, Arias Rivas, Susana, Tejada García, Javier, Beltrán Rodríguez, Iria, Julián-Villaverde, Francisco, Moreno García, María Pilar, Trejo-Gabriel-Galán, José María, Echavarría Iñiguez, Ana, Tejero Juste, Carlos, Pérez Lázaro, Cristina, Marta Moreno, Javier, Tejada Meza, Herbert [0000-0002-6506-1037], Lambea-Gil, Álvaro [0000-0003-1785-9201], Arenillas, Juan F. [0000-0001-7464-6101], Trejo-Gabriel-Galán, José María [0000-0001-9591-8452], Tejada Meza, Herbert, Lambea-Gil, Álvaro, Sancho Saldaña, Agustín, Martínez-Zabaleta, Maite, Riva Juez, Patricia de la, López-Cancio, Elena, Castañón Apilánez, María, Herrera Isasi, María, Marta Enguita, Juan, Lera Alfonso, Mercedes de, Arenillas, Juan F., Segurola Olaizola, Jon, Timiraos Fernández, Juan José, Sánchez, Joaquín, Castellanos-Rodrigo, Mar, Roel, Alexia, Casado Menéndez, Ignacio, Freijo, Mar, Luna, Alain, Palacio Portilla, Enrique, Jiménez López, Yésica, Rodríguez Castro, Emilio, Arias Rivas, Susana, Tejada García, Javier, Beltrán Rodríguez, Iria, Julián-Villaverde, Francisco, Moreno García, María Pilar, Trejo-Gabriel-Galán, José María, Echavarría Iñiguez, Ana, Tejero Juste, Carlos, Pérez Lázaro, Cristina, and Marta Moreno, Javier

Abstract

Background and purpose Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain., Methods Spanish multicenter retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. We recorded the number of patients admitted for ischemic stroke between 30 December 2019 and 3 May 2020, the number of IVT and EVT procedures, and in-hospital mortality., Results In the study period, 2737 patients were admitted with ischemic stroke. There was a decrease in the weekly mean admitted patients during the pandemic (124 vs. 173, p<0.001). In-hospital mortality of stroke patients increased significantly (9.9% vs. 6.5%, p = 0.003), but there were no differences in the proportion of IVT (17.3% vs. 16.1%, p = 0.405) or EVT (22% vs. 23%, p = 0.504)., Conclusion We found a decrease in the number of ischemic stroke admissions and an increase in in-hospital mortality during the COVID-19 epidemic in this large study from North-West Spain. There were regional changes within the network, not fully explained by the severity of the pandemic in different regions.

Published
2020

22. Regulatory T cells participate in the recovery of ischemic stroke patients

Author

Santamaría-Cadavid, María, primary, Rodríguez-Castro, Emilio, additional, Rodríguez-Yáñez, Manuel, additional, Arias-Rivas, Susana, additional, López-Dequidt, Iria, additional, Pérez-Mato, María, additional, Rodríguez-Pérez, Manuel, additional, López-Loureiro, Ignacio, additional, Hervella, Pablo, additional, Campos, Francisco, additional, Castillo, José, additional, Iglesias-Rey, Ramón, additional, and Sobrino, Tomás, additional

Published
2020
Full Text
View/download PDF

23. NT-pro-BNP: A novel predictor of stroke risk after transient ischemic attack

Author

Rodríguez-Castro, Emilio, primary, Hervella, Pablo, additional, López-Dequidt, Iria, additional, Arias-Rivas, Susana, additional, Santamaría-Cadavid, María, additional, López-Loureiro, Ignacio, additional, da Silva-Candal, Andrés, additional, Pérez-Mato, María, additional, Sobrino, Tomás, additional, Campos, Francisco, additional, Castillo, José, additional, Rodríguez-Yáñez, Manuel, additional, and Iglesias-Rey, Ramón, additional

Published
2020
Full Text
View/download PDF

24. Regulatory T cells participate in the recovery of ischemic stroke patients

Author

Santamaría-Cadavid, María, primary, Rodríguez-Castro, Emilio, additional, Rodríguez-Yáñez, Manuel, additional, Arias-Rivas, Susana, additional, López-Dequidt, Iria, additional, Pérez-Mato, María, additional, Rodríguez-Pérez, Manuel, additional, López-Loureiro, Ignacio, additional, Hervella, Pablo, additional, Campos, Francisco, additional, Castillo, José, additional, Iglesias-Rey, Ramón, additional, and Sobrino, Tomás, additional

Published
2019
Full Text
View/download PDF

25. Role of regulatory T-cells on ischemic stroke outcome: new clinical evidences

Author

Santamaría-Cadavid, María, primary, Rodríguez-Castro, Emilio, additional, Rodríguez-Yáñez, Manuel, additional, Arias-Rivas, Susana, additional, López-Dequidt, Iria, additional, Pérez-Mato, María, additional, Rodríguez-Pérez, Manuel, additional, López-Loureiro, Ignacio, additional, Hervella, Pablo, additional, Campos, Francisco, additional, Castillo, José, additional, Iglesias-Rey, Ramón, additional, and Sobrino, Tomás, additional

Published
2019
Full Text
View/download PDF

26. Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis

Author

Rodríguez-Castro, Emilio, primary, Rodríguez-Yáñez, Manuel, additional, Arias, Susana, additional, Santamaría, María, additional, López-Dequidt, Iria, additional, López-Loureiro, Ignacio, additional, Rodríguez-Pérez, Manuel, additional, Hervella, Pablo, additional, Sobrino, Tomás, additional, Campos, Francisco, additional, Castillo, José, additional, and Iglesias-Rey, Ramón, additional

Published
2019
Full Text
View/download PDF

27. Clinical, molecular and cellular study of the obesity paradox in acute ischemic stroke

Author

Rodríguez Castro, Emilio, Castillo Sánchez José Antonio (dir.), Sobrino Moreiras, Tomás, Universidade de Santiago de Compostela. Facultade de Medicina e Odontoloxía, Universidade de Santiago de Compostela. Instituto de Investigacións Sanitarias de Santiago (IDIS), Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermería e Medicina, Castillo Sánchez, José, Facultade de Medicina e Odontoloxía, and Health Research Institute of Santiago de Compostela (IDIS)

Subjects
Inflammation, Investigación::32 Ciencias médicas::3205 Medicina interna::320507 Neurología [Materias], Ischemic stroke, Obesity paradox, Investigación::32 Ciencias médicas::3205 Medicina interna::320502 Endocrinología [Materias], Progenitor cells
Abstract

Stroke and obesity are major global health problems. It has recently emerged the concept of “obesity paradox” to describe the finding of improved prognosis in several diseases in patients with excessive body weight. We performed a case-control study comparing the clinical, molecular and cellular characteristics of obese vs. non-obese patients, with ischemic stroke. Obese patients did not show a worse outcome after ischemic stroke, but also seemed to experience a greater recovery of neurological impairments. All this, despite having several factors strongly associated with bad outcome. We found higher values of the IL-10/IL-6 ratio in obese patients, which suggests that obesity may counterbalance the acute inflammatory reaction through an anti-inflammatory stream enhanced in the first moments of stroke. Furthermore, obesity was associated with a greater mobilization of progenitor cells.

Published
2017

29. Clinical, molecular and cellular study of the obesity paradox in acute ischemic stroke

Author

Castillo Sánchez José Antonio (dir.), Sobrino Moreiras, Tomás, Universidade de Santiago de Compostela. Facultade de Medicina e Odontoloxía, Universidade de Santiago de Compostela. Instituto de Investigacións Sanitarias de Santiago (IDIS), Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermería e Medicina, Rodríguez Castro, Emilio, Castillo Sánchez José Antonio (dir.), Sobrino Moreiras, Tomás, Universidade de Santiago de Compostela. Facultade de Medicina e Odontoloxía, Universidade de Santiago de Compostela. Instituto de Investigacións Sanitarias de Santiago (IDIS), Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermería e Medicina, and Rodríguez Castro, Emilio

Abstract

Stroke and obesity are major global health problems. It has recently emerged the concept of “obesity paradox” to describe the finding of improved prognosis in several diseases in patients with excessive body weight. We performed a case-control study comparing the clinical, molecular and cellular characteristics of obese vs. non-obese patients, with ischemic stroke. Obese patients did not show a worse outcome after ischemic stroke, but also seemed to experience a greater recovery of neurological impairments. All this, despite having several factors strongly associated with bad outcome. We found higher values of the IL-10/IL-6 ratio in obese patients, which suggests that obesity may counterbalance the acute inflammatory reaction through an anti-inflammatory stream enhanced in the first moments of stroke. Furthermore, obesity was associated with a greater mobilization of progenitor cells.

Published
2017

30. Worse Outcome in Stroke Patients Treated with rt-PA Without Early Reperfusion: Associated Factors

Author

Iglesias-Rey, Ramón, primary, Rodríguez-Yáñez, Manuel, additional, Rodríguez-Castro, Emilio, additional, Pumar, José Manuel, additional, Arias, Susana, additional, Santamaría, María, additional, López-Dequidt, Iria, additional, Hervella, Pablo, additional, Correa-Paz, Clara, additional, Sobrino, Tomás, additional, Vivien, Denis, additional, Campos, Francisco, additional, Castellanos, Mar, additional, and Castillo, José, additional

Published
2017
Full Text
View/download PDF

31. Vectorized nanodelivery systems for ischemic stroke: a concept and a need

Author

Da Silva-Candal, Andrés, primary, Argibay, Bárbara, additional, Iglesias-Rey, Ramón, additional, Vargas, Zulema, additional, Vieites-Prado, Alba, additional, López-Arias, Esteban, additional, Rodríguez-Castro, Emilio, additional, López-Dequidt, Iria, additional, Rodríguez-Yáñez, Manuel, additional, Piñeiro, Yolanda, additional, Sobrino, Tomás, additional, Campos, Francisco, additional, Rivas, José, additional, and Castillo, José, additional

Published
2017
Full Text
View/download PDF

34. Stroke care in Galicia: telemedicine in the early, multidisciplinary treatment of all acute stroke cases.

Author

Rodríguez-Castro E, Vázquez-Lima MJ, Rodríguez-Yáñez M, Verde L, and Castillo J

Subjects
Acute Disease, Aged, Early Diagnosis, Female, Hospitals, University, Humans, Male, Middle Aged, Patient Acceptance of Health Care, Pilot Projects, Population Dynamics, Spain, Stroke epidemiology, Time-to-Treatment, Treatment Outcome, Interdisciplinary Communication, Stroke drug therapy, Telemedicine organization & administration, Telemedicine statistics & numerical data, Thrombolytic Therapy
Abstract

En: Stroke is the main cause of morbidity and mortality in Spain and in Galicia in particular. Tissue viability after stroke depends on the time taken to restore circulation. The widely dispersed and aging population of this region challenges efforts to provide equal care for patients with time-sensitive emergencies such as stroke. Two regional hospitals (Hospital do Salnés and Hospital do Barbanza) and the reference Hospital Clínico de Santiago launched a telestroke pilot program in 2011 in which patients whose treatment was guided at a distance were discharged with lower levels of stroke severity and mortality. That outcome was probably attributable to more rapid diagnosis. Given those preliminary results and the characteristics of the population, the centrally coordinated Galician Stroke Care Plan was launched in 2016 to provide a telemedicine service that connects all hospitals in the health system of Galicia. This paper summarizes the experience of developing and implementing the program.

Published
2018

35. [Hypertrophic pachymeningitis secondary to IgG4-related disease: case report and review of the literature].

Author

Rodríguez-Castro E, Fernández-Lebrero A, López-Dequidt IA, Rodríguez-Osorio X, López-González FJ, Suárez-Peñaranda JM, and Arias M

Subjects
Adrenal Cortex Hormones therapeutic use, Autoimmune Diseases of the Nervous System complications, Autoimmune Diseases of the Nervous System diagnosis, Autoimmune Diseases of the Nervous System diagnostic imaging, Autoimmune Diseases of the Nervous System immunology, Autoimmune Diseases of the Nervous System pathology, B-Lymphocytes immunology, Cavernous Sinus pathology, Cerebellopontine Angle pathology, Evoked Potentials, Auditory, Female, Fibrosis, Humans, Hypertrophy, Immunosuppressive Agents therapeutic use, Magnetic Resonance Imaging, Meningitis complications, Meningitis diagnosis, Meningitis diagnostic imaging, Meningitis immunology, Meningitis pathology, Middle Aged, Neuroimaging, Sclerosis, Spinal Cord pathology, Temporal Lobe pathology, Tomography, X-Ray Computed, Autoimmune Diseases of the Nervous System etiology, B-Lymphocytes pathology, Immunoglobulin G analysis, Meningitis etiology
Abstract

Introduction: Hypertrophic pachymeningitis is an infrequent disorder that produces focal or diffuse thickening of the dura mater. It can be idiopathic or secondary to infectious, autoimmune or neoplastic processes. The recently described 'IgG4-related disease' could be the cause of many cases considered cryptogenic., Case Report: A 54-year-old woman, with a history of bronchial asthma, presented with headache, dizziness and hearing loss on her left ear. The brain MRI study with gadolinium showed enhancement and thickening of the dura mater, extending from lateral wall of left cavernous sinus and medial temporal lobe to cerebellopontine angle and ipsilateral tentorium. CSF had 10 leukocytes/µL (90% mononuclear), with 1 g/L protein and without glucose consumption. Pathology showed fibrosis and lymphoplasmacytic infiltrate, with 16 IgG4+ plasma cells per high power field. The rest of analytical and microbiological studies were normal or negative. The plasma IgG4 rate was within normal limits. After treatment with steroids there was clinical improvement accompanied by the virtual disappearance of the alterations detected in neuroimaging., Conclusions: Hypertrophic pachymeningitis as a manifestation of IgG4-related disease can be diagnosed based on MRI findings if plasma IgG4 is elevated. In doubtful cases we must resort to meningeal biopsy. Corticosteroid therapy is usually effective and it is the first line treatment.

Published
2015

Catalog

Books, media, physical & digital resources
See catalog results