1. The i-TED Compton Camera Array for real-time boron imaging and determination during treatments in Boron Neutron Capture Therapy
- Author
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Torres-Sánchez, Pablo, Lerendegui-Marco, Jorge, Balibrea-Correa, Javier, Babiano-Suárez, Victor, Gameiro, Bernardo, Ladarescu, Ion, Álvarez-Rodríguez, Patricia, Daugas, Jean-Michel, Koester, Ulli, Michelagnoli, Caterina, Pedrosa-Rivera, Maria, Porras, Ignacio, Ruiz-Magaña, Maria José, Ruiz-Ruiz, Carmen, and Domingo-Pardo, César
- Subjects
Physics - Medical Physics - Abstract
This paper explores the adaptation and application of i-TED Compton imagers for real-time dosimetry in Boron Neutron Capture Therapy (BNCT). The i-TED array, previously utilized in nuclear astrophysics experiments at CERN, is being optimized for detecting and imaging 478 keV gamma-rays, critical for accurate BNCT dosimetry. Detailed Monte Carlo simulations were used to optimize the i-TED detector configuration and enhance its performance in the challenging radiation environment typical of BNCT. Additionally, advanced 3D image reconstruction algorithms, including a combination of back-projection and List-Mode Maximum Likelihood Expectation Maximization (LM-MLEM), are implemented and validated through simulations. Preliminary experimental tests at the Institut Laue-Langevin (ILL) demonstrate the potential of i-TED in a clinical setting, with ongoing experiments focusing on improving imaging capabilities in realistic BNCT conditions., Comment: 9 pages, 7 figures, submitted to the Special Issue of Applied Radiation and Isotopes associated to the 20th International Congress on Neutron Capture Therapy (20th ICNCT)
- Published
- 2024