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3. List of contributors

Author

Aizawa, Shin-Ichi, primary, Alberdi, Pilar, additional, Alexander, David C., additional, Alía, Alberto, additional, Allison, D.G., additional, Amyes, Sebastian G.B., additional, An, Haoran, additional, Andrade, María J., additional, Antelmann, Haike, additional, Arias, Cesar A., additional, Asensio, Miguel A., additional, Axell-House, Dierdre B., additional, Bae, Hee-Won, additional, Baena, Laura Muñoz, additional, Baig, Abdul Mannan, additional, Bailey, Spenser O., additional, Baize, Sylvain, additional, Baldi, Pablo C., additional, Barbosa, Angela Silva, additional, Barbuddhe, Sukhadeo B., additional, Bard, Emilie, additional, Barry, Eileen M., additional, Basarab, Gregory S., additional, Beloborodova, N.V, additional, Bermúdez, Elena, additional, Bidmos, Fadil A., additional, Bisgaard, Magne, additional, Blakely, Garry W., additional, Bloch, Evan, additional, Boesen, Thias Oberg, additional, Bose, Dipayan, additional, Botero, Javier Enrique, additional, Bouabe, Hicham, additional, Bouchard, Michael J., additional, Bozue, Joel A., additional, Bradbury, Richard S., additional, Brett Moreau, G., additional, Cabezas-Cruz, Alejandro, additional, Cai, Rong-Jun, additional, Calderón, Enrique J., additional, Cao, Boyang, additional, Carmena, David, additional, Carvalho, Eneas, additional, Caulfield, Amanda D., additional, Cen, Shan, additional, Chai, Jong-Yil, additional, Chamberland, Robin R., additional, Champredon, David, additional, Chan, Edward D., additional, Charbon, Godefroid, additional, Chato, Connor, additional, Chelomina, G.N., additional, Chen, Jingyu, additional, Chen, Min, additional, Chen, Shuyu, additional, Chen, Suilin, additional, Chen, Yanfei, additional, Chen, Zhaoyuan, additional, Cheng, Aimin, additional, Cheng, Keding, additional, Chiu, Charles Y., additional, Cho, You-Hee, additional, Christensen, Henrik, additional, Chrtdernevskaya, E.A., additional, Contreras, Adolfo, additional, Contreras, Marinela, additional, Córdoba, Juan J., additional, Córdoba, María G., additional, Costa, Rita, additional, Cote, Christopher K., additional, Cui, Xiangling, additional, Cui, Yujun, additional, Dacal, Elena, additional, Dammann, Allison N., additional, Das, Shubhagata, additional, Dashti, Alejandro, additional, de la Fuente, José, additional, de la Garza, Mireya, additional, Delgado, Josué, additional, Delgado-Cuesta, Juan, additional, Deng, Haiteng, additional, Deng, Li, additional, Dey, Debajit, additional, Dhama, Kuldeep, additional, Diego, Juan García-Bernalt, additional, Ding, Hao, additional, Doern, Christopher D., additional, Dorman, Charles J., additional, Du, Zongmin, additional, Dunbar, Sherry A., additional, Duthie, Malcolm, additional, Dybvig, Kevin F., additional, Eakin, Ann E., additional, Eallonardo, Samuel J., additional, Eberly, Allison R., additional, Echeverry, Adriana Jaramillo, additional, Egland, Paul G., additional, El Zowalaty, Mohamed E., additional, Endsley, Janice Jones, additional, Eom, Keeseon S., additional, Evans, Benjamin A., additional, Falkinham, Joseph O., additional, Feng, Siwei, additional, Feng, Yaoyu, additional, Feng, Zongdi, additional, Fernández-Soto, Pedro, additional, Ferreira, Roux-Cil, additional, Flores-Huerta, Nadia, additional, Foster, Timothy J., additional, Fox-Moon, Sandra M., additional, Fraga, Tatiana Rodrigues, additional, Fredricks, David N., additional, Freitag, Nancy E., additional, Frimodt-Møller, Jakob, additional, Fuller, Risa, additional, Ganesh, Balasubramanian, additional, Gao, Ning, additional, García-Carnero, Laura C., additional, Garzetti, Debora, additional, Geoghegan, Joan A., additional, Ghenim, Raed, additional, Giambartolomei, Guillermo H., additional, Gilbert, Nicole M., additional, Gillis, Thomas Phillip, additional, Gladstone, Camilla A., additional, Gómez-Gaviria, Manuela, additional, Gómez-Marín, Jorge E., additional, Gong, Tengfang, additional, González, Ramón A., additional, Gray-Owen, Scott D., additional, Gu, Bing, additional, Guzmán-Téllez, Paula, additional, Hajal, Caroline, additional, Han, Yanping, additional, Hao, Yi, additional, Harrington, Amanda T., additional, Harris, Jason B., additional, Harvill, Eric T., additional, Hasan, S. Saif, additional, He, Guang-Jun, additional, He, Yongqun, additional, Heffron, Jared D., additional, Hidalgo, Paloma, additional, Hindiyeh, Musa Y., additional, Hreha, Teri N., additional, Hu, Xiaoyu, additional, Huang, Guanghua, additional, Huang, Jiangqing, additional, Huang, Liang, additional, Huang, Shifeng, additional, Huang, Xingxu, additional, Huang, Xueting, additional, Huang, Yilun, additional, Huffman, Anthony, additional, Humphreys, Tricia L., additional, Hunstad, David A., additional, Inglis, Timothy J.J., additional, Isaac, Lourdes, additional, Jacobs, Samantha E., additional, Janowicz, Diane M., additional, Jeon, Hyeong-Kyu, additional, Ji, Quanjiang, additional, Jia, Qi, additional, Jia, Wei, additional, Jin, Shouguang, additional, Jneidi, Lama, additional, Jose, Shinsmon, additional, Jung, Bong-Kwang, additional, Kattan, Randa, additional, Kaushik, Rahul, additional, Khare, Reeti, additional, Kim, Eun Sook, additional, Kirn, Thomas J., additional, Koo, Hyun, additional, Köster, Pamela C., additional, Krause, Peter J., additional, Kumar, Sanjai, additional, Kupz, Andreas, additional, Lambert, P.A., additional, Lamont, Richard J., additional, Langford, Paul R., additional, Lebeaux, David, additional, Legname, Giuseppe, additional, Li, Bin, additional, Li, Chunhao, additional, Li, Fen, additional, Li, Jun, additional, Li, Lanjuan, additional, Li, Ruofan, additional, Li, Ruoyu, additional, Li, Ting, additional, Li, Yang-Yang, additional, Li, Yanhua, additional, Li, Zhuorong, additional, Liang, Xiaomeng, additional, Liao, Guojian, additional, Lin, Ping, additional, Ling, Yun, additional, Liu, Bo, additional, Liu, Dongyou, additional, Liu, Guohua, additional, Liu, Huidi, additional, Liu, Jiafeng, additional, Liu, Jintao, additional, Liu, Qi, additional, Liu, Shu-Lin, additional, Liu, Taiping, additional, Liu, Tongbao, additional, Liu, Wei, additional, Liu, Yan, additional, Liu, Yanni, additional, Liu, Yisong, additional, Liu, Yuan, additional, Løbner-Olesen, Anders, additional, Loeffelholz, Michael, additional, Lu, Hongzhou, additional, Luna, Brian, additional, Ma, Bingting, additional, Ma, Chengying, additional, Ma, Shuang, additional, Ma, TianLi, additional, Madan, Rajat, additional, Mahle, Rachael E., additional, Mahlen, Steven D., additional, Malik, Satya Veer Singh, additional, Malik, Yashpal Singh, additional, Malvy, Denis, additional, Mann, Barbara J., additional, Marasini, Daya, additional, Maris, Alexander S., additional, Marjomäki, Varpu, additional, Marjuki, Henju, additional, Martín, Alberto, additional, Martín, Irene, additional, Martínez-Castillo, Moisés, additional, Martínez-Pabón, María Cecilia, additional, Mathison, Blaine A., additional, Ma’ayeh, Showgy, additional, McDowell, Andrew, additional, McLaughlin, Stephanie E., additional, McSheffrey, Gordon G., additional, Medrano, Francisco J., additional, Meehan, Conor J., additional, Mehta, Dhwani, additional, Mejía-Oquendo, Manuela, additional, Melo-Cristino, José, additional, Mendoza-Barberá, Elena, additional, Meng, Xinan, additional, Merino, Susana, additional, Merritt, Adam J., additional, Miller, Steve, additional, Miller, William R., additional, Minamino, Tohru, additional, Mirzaei, Mohammadali Khan, additional, Mora-Montes, Héctor M., additional, Mortensen, Joel, additional, Mostafa, Heba H., additional, Muhsen, Khitam, additional, Mujahed, Ahlam, additional, Muro, Antonio, additional, Murphy, Olwen C., additional, Newton, Hayley J., additional, Nguyen, April H., additional, Nichols, Wright W., additional, Niu, Siqiang, additional, Núñez, Félix, additional, Obregon, Dasiel, additional, Okamoto, Akira, additional, Okutani, Akiko, additional, Olabode, Abayomi, additional, Omar, Muna, additional, Ong, Edison, additional, Ouyang, Zhiming, additional, Pacak, Christina A., additional, Pacheco-Yépez, Judith, additional, Palmer, John, additional, Pang, Xiaoli, additional, Paredes-Sabja, Daniel, additional, Peng, Zhong, additional, Peng, Zonggen, additional, Pérez-Nevado, Francisco, additional, Poon, Art, additional, Pospíšilová, Petra, additional, Potts, Caelin C., additional, Pu, Qinqin, additional, Pujic, Petar, additional, Qi, Rui, additional, Qian, Chenyun, additional, Qian, Liu, additional, Qin, Aiping, additional, Qu, Fen, additional, Rakin, Alexander, additional, Ramesh, Ashwin, additional, Ramirez, Mario, additional, Rao, Yu, additional, Ratner, Adam J., additional, Rawool, Deepak B., additional, Rehman, Asma, additional, Ren, Jie, additional, Ren, Ping, additional, Retchless, Adam C., additional, Robertson, Erle S., additional, Rodríguez, Alicia, additional, Rodriguez, Azucena, additional, Rodríguez-Medina, Carolina, additional, Rodriguez-Nava, Veronica, additional, Rohde, Manfred, additional, Romero-Rodríguez, Alba, additional, Rosales-Morgan, Gabriela, additional, Rosenkranz, Andrea L., additional, Ruiz-Moyano, Santiago, additional, Ruokolainen, Visa, additional, Sabateen, Ali, additional, Sahu, Radhakrishna, additional, Sails, Andrew, additional, Sang, Yu, additional, Santana, Clarissa H., additional, Santos, Jesus A., additional, Santos, Renato L., additional, Schmitz, Jonathan E., additional, Serrano-Luna, Jesús, additional, Shen, Jianzhong, additional, Shen, Zhangqi, additional, Shibayama, Mineko, additional, Shirtliff, Mark E., additional, Silva-Costa, Catarina, additional, Silva-Olivares, Angélica, additional, Singh, Niraj Kumar, additional, Šmajs, David, additional, Smith, Robert P., additional, Smith, Sophie, additional, Snyder, Lori A.S., additional, Song, Yinggai, additional, Soro, Aurea Simon, additional, Spearman, Paul, additional, Spellberg, Brad, additional, Sprague, Lisa D., additional, Stratton, Charles W., additional, Strenk, Susan M., additional, Strugnell, Richard A., additional, Sun, Keer, additional, Suo, Xun, additional, Suzuki-Hatano, Silveli, additional, Svärd, Staffan, additional, Talbot, Elizabeth A., additional, Tamez-Castrellón, Alma K., additional, Tan, Nie, additional, Tang, Cynthia Y., additional, Tang, Yi-Wei, additional, Tao, Jia, additional, Tao, Lili, additional, Terrero-Salcedo, David, additional, Tharmalingam, Jayaraman, additional, Thwe, Phyu M., additional, Tiamani, Kawtar, additional, Tomás, Juan M., additional, Topaz, Nadav, additional, Tsai, Ang-Chen, additional, Tsalik, Ephraim L., additional, Tuomanen, Elaine I., additional, Turenne, Christine Y., additional, Tyagi, Anuj, additional, Uprety, Priyanka, additional, Valour, Florent, additional, van Hensbergen, Vincent P., additional, Venkatesan, Arun, additional, Vergis, Jess, additional, Villar, Margarita, additional, Vollmer, Waldemar, additional, Waites, Ken B., additional, Wan, Xiu-Feng, additional, Wang, Guiqing, additional, Wang, Lijun, additional, Wang, Lin, additional, Wang, Linqi, additional, Wang, Xiangru, additional, Wang, Xin, additional, Wang, Xinjie, additional, Wang, Ya-Ting, additional, Wang, Yang, additional, Wang, Yating, additional, Weil, Ana A., additional, Welkos, Susan L., additional, Wengenack, Nancy L., additional, Westblade, Lars F., additional, Whitfield, Chris, additional, Wu, Hui, additional, Wu, Lijuan, additional, Wu, Min, additional, Wu, Yarong, additional, Wu, Zhaowei, additional, Xiang, Ye, additional, Xiao, Di, additional, Xiao, Li, additional, Xiao, Lihua, additional, Xu, Tao, additional, Xu, Wenyue, additional, Xu, Xinping, additional, Xue, Jinling, additional, Yadav, Jay Prakash, additional, Yan, Junxiang, additional, Yan, Yixin, additional, Yang, Changmei, additional, Yang, Ruifu, additional, Yang, Ying, additional, Yao, Kaihu, additional, Yao, Yu-Feng, additional, Yeakle, Kyle C., additional, Yu, Demin, additional, Yu, Hao, additional, Yu, Xue-Jie, additional, Yuan, Zhenghong, additional, Zai, Wenjing, additional, Zhang, Jianzhong, additional, Zhang, Jing-Ren, additional, Zhang, Lanyue, additional, Zhang, Lijie, additional, Zhang, Qiwei, additional, Zhang, Wenbao, additional, Zhang, Wenhong, additional, Zhang, Xinxin, additional, Zhao, Youbao, additional, Zhou, Chuanmin, additional, Zhu, Feng, additional, Zhu, Jingting, additional, and Zhu, Yongqun, additional

Published
2024
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4. Pathogenesis of fungal infections

Author

Ruiz-Moyano, Santiago, primary, Pérez-Nevado, Francisco, additional, Rodríguez, Alicia, additional, Córdoba, María G., additional, Martín, Alberto, additional, and Córdoba, Juan J., additional

Published
2024
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9. Photodynamic Therapy

Author

Díaz-Jiménez, José Pablo, Rodríguez, Alicia N., Díaz-Jiménez, José Pablo, editor, and Rodríguez, Alicia N., editor

Published
2023
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10. Rigid Broncoscopy

Author

Díaz-Jiménez, José Pablo, Rodríguez, Alicia N., Díaz-Jiménez, José Pablo, editor, and Rodríguez, Alicia N., editor

Published
2023
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21. Consenso mexicano de expertos sobre el uso del sistema flash de monitoreo de glucosa en diabetes mellitus tipo 2

Author

Lavalle-González, Fernando J., primary, Yépez-Rodríguez, Alicia E., additional, Garduño-Pérez, Ángel A., additional, Martínez-Abundis, Eduardo, additional, Cetina-Canto, José A., additional, Garnica-Cuellar, Juan C., additional, Vera-Zertuche, Juan M., additional, de la Garza-Hernández, Natalia E., additional, Almeda-Valdés, Paloma, additional, and Faradji-Hazan, Raquel N., additional

Published
2024
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30. Disposición de los pobladores de Mezcala de la Asunción, México, para solucionar la problemática de residuos sólidos a partir de su narrativa biocultural: un estudio cualitativo desde la Teoría del Comportamiento Planificado (TCP)

Author

Aldape García, Angel Omar, Torres-Rodríguez, Alicia, Patiño Palomares, Marco Luis, Aldape García, Angel Omar, Torres-Rodríguez, Alicia, and Patiño Palomares, Marco Luis

Abstract

This study explores how the behavioral intention of the residents of Mezcala de la Asunción is influenced by their biocultural context (culture and natural environment) to create strategic ideas and solutions to the problem of the accumulation, management and final disposal of waste. The methodological design was qualitative and interpretive, and it was guided by the application of the Theory of Planned Behavior (TPB). Each narrative segment was aligned to the definition of each of the variables that compose the TPB. The methods used were 11 individual interviews, 4 focus groups and 51 photographs. The results suggest that the residents of Mezcala still maintain a connection to their natural environment that strongly influenced as a positive moderator the three central variables of the TPB: attitude towards behaviour, subjective norm and perceived control. These results could increase villager’s bhavioral intention to participate in a collective strategy to reduce garbage in…, Cette étude explore comment l'intention comportementale des habitants de la Mezcala de la Asunción, à Jalisco, est influencée par leur contexte bioculturel (culture et environnement naturel) pour créer des idées et des solutions stratégiques au problème de l'accumulation des déchets. La conception méthodologique est qualitative et interprétative guidée par la théorie du comportement planifié (TCP). Chaque segment narratif a été aligné sur la définition de chacune des variables qui composent le TCP. Les méthodes utilisées dans la phase de collecte des données ont été : 11 entretiens individuels, 4 focus groupes et 51 photographies. Les résultats suggèrent que les habitants de Mezcala maintiennent toujours un lien avec leur environnement naturel, ce qui influence fortement en tant que modérateur positif les trois variables centrales du CPT : Attitude envers le comportement, Norme subjective et Contrôle perçu. Ces résultats peuvent accroître l'intention comportementale des habitants à participer à une stratégie collective., Questo studio esplora come l'intenzione comportamentale dei residenti di Mezcala de la Asunción, a Jalisco, sia influenzata dal loro contesto bioculturale (cultura e ambiente naturale) per creare idee e soluzioni strategiche al problema dell'accumulo di rifiuti. Il disegno metodologico è qualitativo e interpretativo guidato dalla Teoria del Comportamento Pianificato (TCP). Ogni segmento narrativo è stato allineato alla definizione di ciascuna delle variabili che compongono il TCP. Le modalità utilizzate nella fase di raccolta dati sono state: 11 interviste individuali, 4 focus group e 51 fotografie. I risultati suggeriscono che i residenti di Mezcala mantengono ancora una connessione con il loro ambiente naturale, che influenza fortemente come moderatore positivo le tre variabili centrali del CPT: Atteggiamento verso il comportamento, Norma soggettiva e Controllo percepito. Questi risultati possono aumentare l'intenzione comportamentale degli abitanti di partecipare a una strategia collettiva., Este estudo explora como a intenção comportamental dos moradores de Mezcala de la Asunción, em Jalisco, é influenciada por seu contexto biocultural (cultura e ambiente natural) para criar ideias e soluções estratégicas para o problema do acúmulo de lixo. O delineamento metodológico é qualitativo e interpretativo pautado na Teoria do Comportamento Planejado (TCP). Cada segmento narrativo foi alinhado à definição de cada uma das variáveis que compõem o TCP. Os métodos utilizados na fase de recolha de dados foram: 11 entrevistas individuais, 4 grupos focais e 51 fotografias. Os resultados sugerem que os moradores de Mezcala ainda mantêm uma conexão com seu ambiente natural, o que influencia fortemente como moderador positivo as três variáveis centrais do CPT: Atitude em relação ao comportamento, Norma subjetiva e Controle percebido. Esses resultados podem aumentar a intenção comportamental dos moradores de participar de uma estratégia coletiva., Este estudio explora cómo la intención conductual de los residentes de Mezcala de la Asunción, en Jalisco, es influenciada por su contexto biocultural (cultura y entorno natural) para crear ideas y soluciones estratégicas al problema de la acumulación de la basura. El diseño metodológico es cualitativo e interpretativo y está guiado por la Teoría del Comportamiento Planificado (TCP). Cada segmento narrativo se alineó a la definición de cada una de las variables que componen la TCP. Los métodos utilizados en la fase de recolección de datos fueron once entrevistas individuales, cuatro grupos focales y 51 fotografías. Los resultados sugieren que los residentes de Mezcala aún mantienen una conexión con su entorno natural, el cual influye fuertemente como moderador positivo en las tres variables centrales de la TPC: la actitud hacia el comportamiento, la norma subjetiva y el control percibido. Estos resultados pueden incrementar la intención conductual de los pobladores...

Published
2024

31. Prevalence and associated factors of sexual, psychological, and physical violence among physical therapists in their clinical role in Spain: a national web-based cross-sectional survey

Author

Boo-Mallo, Tania, Oviedo-de-la-Fuente, Manuel, Martínez-Rodríguez, Alicia, Boo-Mallo, Tania, Oviedo-de-la-Fuente, Manuel, and Martínez-Rodríguez, Alicia

Abstract

[Abstract] Objectives: To determine the extent of career-long and 12-month exposure to sexual, physical, and psychological/verbal violence committed by patients or their companions among physical therapists in Spain. Additionally, to identify the factors associated with such exposure. Methods: This study employed an observational cross-sectional approach. Initially, a questionnaire was developed and validated using a convenience sample. Subsequently, it was distributed via email to all physical therapists registered in Spain in the first quarter of 2022. Individual risk models were created for each type of violence experienced within the past 12 months. Results: The prevalence of violence encountered by physical therapists throughout their careers was 47.9% for sexual violence, 42.7% for psychological/verbal abuse, and 17.6% for physical abuse. Lower values were observed within the last 12 months (13.4%, 15.8%, and 5.2%, respectively). Statistical risk modeling for each type of violence experienced in the past 12 months indicated that the common precipitating factor for all forms of violence was working with patients with cognitive impairment. Working part-time appeared to be a protective factor. Other factors, such as the practitioners' gender, practice setting, or clinic location showed variations among the diverse types of violence. Conclusions: The exposure to type II workplace violence within the last 12 months among physical therapists in Spain (Europe) is not so high as in some other world regions. Various individual, clinical, and professional/organizational risk factors have been identified in connection with type II workplace violence. Further research is warranted to compare the violence experienced once the COVID pandemic has subsided.

Published
2024

34. Facial and Emotion Recognition Deficits in Myasthenia Gravis.

Author

García-Sanchoyerto, Maddalen, Salgueiro, Monika, Ortega, Javiera, Rodríguez, Alicia Aurora, Parada-Fernández, Pamela, and Amayra, Imanol

Subjects
CROSS-sectional method, NEUROMUSCULAR diseases, DYSARTHRIA, CRONBACH'S alpha, RESEARCH funding, MYASTHENIA gravis, STATISTICAL sampling, INTERVIEWING, FATIGUE (Physiology), KRUSKAL-Wallis Test, EMOTIONS, ANXIETY, SEVERITY of illness index, DESCRIPTIVE statistics, CHI-squared test, MANN Whitney U Test, ANALYSIS of covariance, MULTIVARIATE analysis, CHRONIC diseases, MUSCLE weakness, SOCIAL case work, SOCIAL integration, RESEARCH methodology, AUTOIMMUNE diseases, QUALITY of life, SPEECH disorders, INTERPERSONAL relations, PSYCHOLOGICAL tests, COMPARATIVE studies, DATA analysis software, FACIAL expression, MENTAL depression, DEGLUTITION disorders, COGNITION, NONPARAMETRIC statistics, SYMPTOMS
Abstract

Myasthenia gravis (MG) is a neuromuscular disease of autoimmune etiology and chronic evolution. In addition to the muscle weakness and fatigue that characterize MG, in some studies patients show an inferior performance in cognitive tasks and difficulties in recognizing basic emotions from facial expressions. However, it remains unclear if these difficulties are due to anxious–depressive symptoms that these patients present or related to cognitive abilities, such as facial recognition. This study had a descriptive cross-sectional design with a sample of 92 participants, 52 patients with MG and 40 healthy controls. The data collection protocol included measures to assess recognition of facial expressions (BRFT), facial emotional expression (FEEL), and levels of anxiety and depression (HADS). The MG group had worse performance than the control group in recognizing "fear" (p = 0.001; r = 0.344), "happiness" (p = 0.000; r = 0.580), "disgust" (p = 0.000; r = 0.399), "surprise" (p = 0.000; r = 0.602), and "anger" (p = 0.007; r = 0.284). Likewise, the MG group also underperformed in facial recognition (p = 0.001; r = 0.338). These difficulties were not related to their levels of anxiety and depression. Alterations were observed both in the recognition of facial emotions and in facial recognition, without being mediated by emotional variables. These difficulties can influence the interpersonal interaction of patients with MG. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Exploring a Cheese Ripening Process That Hinders Ochratoxin A Production by Penicillium nordicum and Penicillium verrucosum.

Author

Rodríguez, Alicia, Magan, Naresh, and Delgado, Josué

Subjects
*CHEESEMAKING, *CHEESE ripening, *CARCINOGENS, *CHEESE products, *CHEESE industry, *OCHRATOXINS
Abstract

Simple Summary: Ochratoxin A (OTA), a nephrotoxic mycotoxin categorized as a possible carcinogenic agent, is a current problem in the cheese manufacturing industry. The main OTA producers are Penicillium nordicum and Penicillium verrucosum. Therefore, we aimed to investigate different cheese ripening phases to hinder OTA production. We elaborated cheese analogues, inoculated both fungal species, and performed two different ripening phases, at 10 and 15 °C. Despite the fact that both were able to grow, they did not express genes related to OTA production, and no OTA was detected during two weeks of ripening. Therefore, we show that, when the first phases of ripening are maintained at <15 °C, the possibility of OTA production is dramatically minimized. This information is of utmost importance for industries to enhance the safety of their cheese products, which positively impacts human health. A lack of control of the technological abiotic parameters apparent during cheese manufacture, including temperature and relative humidity, results in this dairy product being prone to mold contamination. Sometimes, inoculant molds are used to obtain the characteristic sensory properties of this type of product. However, during the maturation process, some unwanted molds can colonize the ripening cheese and produce mycotoxins. Mycotoxigenic molds such as Penicillium nordicum and Penicillium verrucosum can colonize ripened cheeses, contaminating them with ochratoxin A (OTA), a nephrotoxic 2B toxin. Thus, the presence of OTA in cheeses could represent a hazard to consumers' health. This study has evaluated the growth and OTA production of P. nordicum and P. verrucosum on a cheese analogue under simulated ripening conditions of 10 and 15 °C and 0.96 water activity (aw). Ecophysiological, molecular, and analytical tools assessed the mold growth, gene expression, and OTA production under these environmental conditions. Both species were able to effectively colonize the cheese under these ripening conditions. However, neither species expressed the otapks and otanps biosynthetic genes or produced phenotypic OTA. Therefore, these results suggest a relatively low risk of exposure to OTA for consumers of this type of cheese product. The conditions used were thus appropriate for cheese ripening to minimize the potential for contamination with such mycotoxins. An appropriate adjustment of the technological ripening parameters during such cheese manufacture could contribute to OTA-free cheeses. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Effects of a neuropsychosocial teleassistance intervention on social cognition and health-related quality of life of pediatric patients with neuromuscular diseases.

Author

García, Irune, Martínez, Oscar, Amayra, Imanol, Salgueiro, Monika, Rodríguez, Alicia Aurora, and López-Paz, Juan Francisco

Subjects
COGNITIVE therapy, QUALITY of life, THEORY of mind, NEUROMUSCULAR diseases, CHILD patients
Abstract

Objective This study aimed to determine the effects of a neuropsychosocial teleassistance group-based intervention on improving social cognitive functioning and health-related quality of life (HRQoL) in pediatric neuromuscular diseases (NMD). Methods Thirty-five pediatric patients with NMD were assigned to the neuropsychosocial intervention program (n  = 20) or waiting list control condition (n  = 15). The intervention group received an integrative approach that combines training in social cognition with cognitive behavioral therapy. All participants completed a neuropsychological and clinical assessment at baseline and follow-up, which included tests of social cognition, both for emotion recognition and theory of mind, and HRQoL. Repeated-measures multivariate analysis of covariance was used to determine the effects of the teleassistance program. Results Group × Time interactions revealed significant improvements in the intervention group as compared with the control group for different social cognition's indicators (AR NEPSY-II: p  =  .003, η 2p =.24; TM NEPSY: p  <  .001, η 2p =.35; Verbal task: p  <  .001, η 2p =.35; Happé's Strange Stories: p  =  .049, η 2p =.11) and HRQoL (Psychosocial health: p  =  .012, η 2p =.18; Emotional functioning: p  =  .037, η 2p = 0.13; Social functioning: p  =  .006, η 2p =.21; Total: p  =  .013, η 2p =.17), showing medium to large effects. Conclusions Patients receiving the neuropsychosocial intervention showed improvements in their social cognition performance and psychosocial HRQoL, providing evidence about the positive effects of the program in pediatric patients with NMD. This should be considered in further research and interventions in this field. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Encapsulation of Cinnamaldehyde and Vanillin as a Strategy to Increase Their Antimicrobial Activity.

Author

Sepúlveda, Francisco, Puente-Diaz, Luis, Ortiz-Viedma, Jaime, Rodríguez, Alicia, and Char, Cielo

Subjects
ESCHERICHIA coli O157:H7, ANTI-infective agents, WHEY protein concentrates, VANILLIN, ESCHERICHIA coli, LISTERIA innocua
Abstract

Many studies have suggested that the encapsulation of natural antimicrobials increases their antimicrobial activity. In this sense, the objective was to study the inactivation of microorganisms with encapsulated cinnamaldehyde and vanillin (E-CIN and E-VN), in comparison with the unencapsulated antimicrobials (CIN and VN) in protein beverages. Additionally, the microbial response was quantified through mathematical modeling. Cinnamaldehyde and vanillin were encapsulated using whey protein concentrate (WPC) as the encapsulating agent. The effectiveness at inactivating Escherichia coli, Listeria innocua, and Saccharomyces cerevisiae was evaluated in a protein-apple juice beverage during storage (4 °C). Encapsulation increased the effectiveness of cinnamaldehyde, reaching reductions of 1.8, 3.3, and 5.3 log CFU/mL in E. coli, L. innocua, and S. cerevisiae, respectively, while vanillin encapsulation had little effect on antimicrobial activity, reducing by 0.5, 1.4, and 1.1 log cycles, respectively. The combined treatments (E-CIN + E-VN) had an additive effect in reducing E. coli and a synergistic effect against S. cerevisiae. The Gompertz model was more versatile and better described the biphasic curves, whereas the Weibull model complemented the information regarding the spectrum of resistances within the microbial population. In conclusion, the encapsulation of cinnamaldehyde with WPC enhanced its activity. However, further studies are necessary to improve the antimicrobial activity of vanillin. [ABSTRACT FROM AUTHOR]

Published
2024
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38. Optimization of Oil and Tocopherol Extraction from Maqui (Aristotelia chilensis (Mol.) Stuntz) by Supercritical CO 2 Procedure.

Author

Sánchez, Camila, Rodríguez, Alicia, Reinoso, Francisca, Dovale-Rosabal, Gretel, Romero, Nalda, Espinosa, Alejandra, Pando, María Elsa, Claria, Benjamín, Valenzuela, Rodrigo, Char, Cielo, and Aubourg, Santiago P.

Subjects
SUPERCRITICAL fluid extraction, RESPONSE surfaces (Statistics), GALLIC acid, OXIDANT status, CARBON dioxide
Abstract

This study focused on the oil extraction from freeze-dried maqui (Aristotelia chilensis) by supercritical fluid extraction with carbon dioxide (SFE-CO2). The basic objective was to optimize the oil yield and the tocopherol concentration. A Box/Behnken experimental design was developed with three processing variables: supercritical pressure (74, 187, and 300 bar), temperature (35, 48, and 60 °C), and extracting time (30, 135, and 240 min). Multiple optimizations, based on the combination of factor levels at 274 bar, 240 min, and 60 °C, led to the highest oil yield and tocopherol values. The validation of the optimized conditions of maqui oil extraction led to an oil yield of 8% and values of 735, 53, and 97 (mg·kg−1 oil) for α-tocopherol, α-tocotrienol, and γ-tocopherol, respectively. A higher concentration of tocopherol compounds was observed when compared to the employment of the conventional extracting method. The optimized SFE-CO2 method led to an oil extract exhibiting higher Hydrophilic-Oxygen Radical Absorbance Capacity (H-ORAC) assay and total phenol content (22 μmol Trolox equivalents·g−1 oil and 28 mg gallic acid equivalents·g−1 oil) than the oil obtained by the conventional procedure. A practical and accurate oil extraction is proposed for obtaining tocopherol-enriched oil including high concentrations of valuable lipophilic antioxidants. [ABSTRACT FROM AUTHOR]

Published
2024
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39. Afectividad y disidencias de la facticidad.

Author

García, José Ordóñez, Coordinación, Vieira, Ignacio, Santamaría, Manuel, De Bravo Delorme, Cristián, Gilabert, Fernando, de Mingo Rodríguez, Alicia Mª, Moreno-Márquez, César, Ribas, José Ángel Rodríguez, de Jesús Fernández Mora, Vicente, Periñán, Juan José Garrido, Uche, Miguel Grijalba, Ordóñez-García, José, Martín, Francisco Romero, García, José Ordóñez, Vieira, Ignacio, Santamaría, Manuel, De Bravo Delorme, Cristián, Gilabert, Fernando, de Mingo Rodríguez, Alicia Mª, Moreno-Márquez, César, Ribas, José Ángel Rodríguez, de Jesús Fernández Mora, Vicente, Periñán, Juan José Garrido, Uche, Miguel Grijalba, Ordóñez-García, José, and Martín, Francisco Romero

Published
2023

41. Real-World Characteristics and Outcome of Patients Treated With Single-Agent Ibrutinib for Chronic Lymphocytic Leukemia in Spain (IBRORS-LLC Study)

Author

Abrisqueta, Pau, Loscertales, Javier, Terol, Maria José, Ramírez Payer, Ángel, Ortiz, Macarena, Pérez, Inmaculada, Cuellar-García, Carolina, Fernández de la Mata, Margarita, Rodríguez, Alicia, Lario, Ana, Delgado, Julio, Godoy, Ana, Arguiñano Pérez, José Mª, Berruezo, Mª José, Oliveira, Ana, Hernández-Rivas, José-Ángel, García Malo, Maria Dolores, Medina, Ángeles, García Martin, Paloma, Osorio, Santiago, Baltasar, Patricia, Fernández-Zarzoso, Miguel, Marco, Fernando, Vidal Manceñido, Mª Jesús, Smucler Simonovich, Alicia, López Rubio, Montserrat, Jarque, Isidro, Suarez, Alexia, Fernández Álvarez, Rubén, Lancharro Anchel, Aima, Ríos, Eduardo, Losada Castillo, María del Carmen, Pérez Persona, Ernesto, García Muñoz, Ricardo, Ramos, Rafael, Yáñez, Lucrecia, Bello, José Luis, Loriente, Cristina, Acha, Daniel, and Villanueva, Miguel

Published
2021
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47. Glycemic control, treatment and complications in patients with type 1 diabetes amongst healthcare settings in Mexico

Author

Antonio-Villa, Neftali Eduardo, García-Tuomola, Aili, Almeda-Valdes, Paloma, Vidrio-Velázquez, Maricela, Islas-Ortega, Laura, Madrigal-Sanromán, Juan R., Zaballa-Lasso, Carmenmari, Martínez-Ramos-Méndez, Angélica, De la Garza-Hernández, Natalia E., Bustamante-Martínez, Jorge F., González-Galvez, Guillermo, Valadez-Capetillo, Mayra, Sanchez-Ruiz, Karla L., Castillo-Galindo, Carmen, Yepez-Rodríguez, Alicia E., Polanco-Preza, Miguel A., Ceballos-Macías, Jose J., Valenzuela-Montoya, Julio C., Escobedo-Ortiz, Ana R., Ferreira-Hermosillo, Aldo, Rodríguez-Sanchez, Ester, Romero-Zazueta, Alejandro, Miracle-López, Sigfrido, Figueroa-Andrade, Mario H., and Faradji, Raquel N.

Published
2021
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