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3. Robust Optimization for IMPT: Introducing and Comparing Different Automated Approaches

Author

Neves, Joana, Rocha, Humberto, Ferreira, Brígida, Dias, Joana, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Garau, Chiara, editor, Taniar, David, editor, C. Rocha, Ana Maria A., editor, and Faginas Lago, Maria Noelia, editor

Published
2024
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6. Plasma C24:0 ceramide impairs adipose tissue remodeling and promotes liver steatosis and glucose imbalance in offspring of rats

Author

Camacho-Morales, Alberto, Noriega, Lilia G., Sánchez-García, Adriana, Torre-Villalvazo, Ivan, Vázquez-Manjarrez, Natalia, Maldonado-Ruiz, Roger, Cárdenas-Tueme, Marcela, Villegas-Romero, Mariana, Alamilla-Martínez, Itzayana, Rodriguez-Rocha, Humberto, Garcia-Garcia, Aracely, Corona, Juan Carlos, Tovar, Armando R., Saville, Jennifer, Fuller, Maria, Gonzalez-Gonzalez, José Gerardo, and Rivas-Estilla, Ana María

Published
2024
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8. Tropical forests are approaching critical temperature thresholds

Author

Doughty, Christopher E., Keany, Jenna M., Wiebe, Benjamin C., Rey-Sanchez, Camilo, Carter, Kelsey R., Middleby, Kali B., Cheesman, Alexander W., Goulden, Michael L., da Rocha, Humberto R., Miller, Scott D., Malhi, Yadvinder, Fauset, Sophie, Gloor, Emanuel, Slot, Martijn, Oliveras Menor, Imma, Crous, Kristine Y., Goldsmith, Gregory R., and Fisher, Joshua B.

Published
2023
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10. Nanoencapsulation of extracts and isolated compounds of plant origin and their cytotoxic effects on breast and cervical cancer treatments: Advantages and new challenges

Author

Guillén-Meléndez, Gloria A., Pérez-Hernández, Raymundo A., Chávez-Montes, Abelardo, Castillo-Velázquez, Uziel, de Jesús Loera-Arias, María, Montes-de-Oca-Saucedo, Carlos R., Rodríguez-Rocha, Humberto, Contreras-Torres, Flavio F., Saucedo-Cárdenas, Odila, and Soto-Domínguez, Adolfo

Published
2024
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12. Comparison of Hybrid Direct-Search Approaches for Beam Angle Optimization in Intensity-Modulated Proton Therapy

Author

Rocha, Humberto, Dias, Joana, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Rocha, Ana Maria A. C., editor, Garau, Chiara, editor, Scorza, Francesco, editor, Karaca, Yeliz, editor, and Torre, Carmelo M., editor

Published
2023
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16. Author Correction: The FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data.

Author

Pastorello, Gilberto, Trotta, Carlo, Canfora, Eleonora, Chu, Housen, Christianson, Danielle, Cheah, You-Wei, Poindexter, Cristina, Chen, Jiquan, Elbashandy, Abdelrahman, Humphrey, Marty, Isaac, Peter, Polidori, Diego, Reichstein, Markus, Ribeca, Alessio, van Ingen, Catharine, Vuichard, Nicolas, Zhang, Leiming, Amiro, Brian, Ammann, Christof, Arain, M Altaf, Ardö, Jonas, Arkebauer, Timothy, Arndt, Stefan K, Arriga, Nicola, Aubinet, Marc, Aurela, Mika, Baldocchi, Dennis, Barr, Alan, Beamesderfer, Eric, Marchesini, Luca Belelli, Bergeron, Onil, Beringer, Jason, Bernhofer, Christian, Berveiller, Daniel, Billesbach, Dave, Black, Thomas Andrew, Blanken, Peter D, Bohrer, Gil, Boike, Julia, Bolstad, Paul V, Bonal, Damien, Bonnefond, Jean-Marc, Bowling, David R, Bracho, Rosvel, Brodeur, Jason, Brümmer, Christian, Buchmann, Nina, Burban, Benoit, Burns, Sean P, Buysse, Pauline, Cale, Peter, Cavagna, Mauro, Cellier, Pierre, Chen, Shiping, Chini, Isaac, Christensen, Torben R, Cleverly, James, Collalti, Alessio, Consalvo, Claudia, Cook, Bruce D, Cook, David, Coursolle, Carole, Cremonese, Edoardo, Curtis, Peter S, D'Andrea, Ettore, da Rocha, Humberto, Dai, Xiaoqin, Davis, Kenneth J, De Cinti, Bruno, de Grandcourt, Agnes, De Ligne, Anne, De Oliveira, Raimundo C, Delpierre, Nicolas, Desai, Ankur R, Di Bella, Carlos Marcelo, di Tommasi, Paul, Dolman, Han, Domingo, Francisco, Dong, Gang, Dore, Sabina, Duce, Pierpaolo, Dufrêne, Eric, Dunn, Allison, Dušek, Jiří, Eamus, Derek, Eichelmann, Uwe, ElKhidir, Hatim Abdalla M, Eugster, Werner, Ewenz, Cacilia M, Ewers, Brent, Famulari, Daniela, Fares, Silvano, Feigenwinter, Iris, Feitz, Andrew, Fensholt, Rasmus, Filippa, Gianluca, Fischer, Marc, Frank, John, Galvagno, Marta, and Gharun, Mana

Abstract

The following authors were omitted from the original version of this Data Descriptor: Markus Reichstein and Nicolas Vuichard. Both contributed to the code development and N. Vuichard contributed to the processing of the ERA-Interim data downscaling. Furthermore, the contribution of the co-author Frank Tiedemann was re-evaluated relative to the colleague Corinna Rebmann, both working at the same sites, and based on this re-evaluation a substitution in the co-author list is implemented (with Rebmann replacing Tiedemann). Finally, two affiliations were listed incorrectly and are corrected here (entries 190 and 193). The author list and affiliations have been amended to address these omissions in both the HTML and PDF versions.

Published
2021

18. The FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data.

Author

Pastorello, Gilberto, Trotta, Carlo, Canfora, Eleonora, Chu, Housen, Christianson, Danielle, Cheah, You-Wei, Poindexter, Cristina, Chen, Jiquan, Elbashandy, Abdelrahman, Humphrey, Marty, Isaac, Peter, Polidori, Diego, Reichstein, Markus, Ribeca, Alessio, van Ingen, Catharine, Vuichard, Nicolas, Zhang, Leiming, Amiro, Brian, Ammann, Christof, Arain, M Altaf, Ardö, Jonas, Arkebauer, Timothy, Arndt, Stefan K, Arriga, Nicola, Aubinet, Marc, Aurela, Mika, Baldocchi, Dennis, Barr, Alan, Beamesderfer, Eric, Marchesini, Luca Belelli, Bergeron, Onil, Beringer, Jason, Bernhofer, Christian, Berveiller, Daniel, Billesbach, Dave, Black, Thomas Andrew, Blanken, Peter D, Bohrer, Gil, Boike, Julia, Bolstad, Paul V, Bonal, Damien, Bonnefond, Jean-Marc, Bowling, David R, Bracho, Rosvel, Brodeur, Jason, Brümmer, Christian, Buchmann, Nina, Burban, Benoit, Burns, Sean P, Buysse, Pauline, Cale, Peter, Cavagna, Mauro, Cellier, Pierre, Chen, Shiping, Chini, Isaac, Christensen, Torben R, Cleverly, James, Collalti, Alessio, Consalvo, Claudia, Cook, Bruce D, Cook, David, Coursolle, Carole, Cremonese, Edoardo, Curtis, Peter S, D'Andrea, Ettore, da Rocha, Humberto, Dai, Xiaoqin, Davis, Kenneth J, Cinti, Bruno De, Grandcourt, Agnes de, Ligne, Anne De, De Oliveira, Raimundo C, Delpierre, Nicolas, Desai, Ankur R, Di Bella, Carlos Marcelo, Tommasi, Paul di, Dolman, Han, Domingo, Francisco, Dong, Gang, Dore, Sabina, Duce, Pierpaolo, Dufrêne, Eric, Dunn, Allison, Dušek, Jiří, Eamus, Derek, Eichelmann, Uwe, ElKhidir, Hatim Abdalla M, Eugster, Werner, Ewenz, Cacilia M, Ewers, Brent, Famulari, Daniela, Fares, Silvano, Feigenwinter, Iris, Feitz, Andrew, Fensholt, Rasmus, Filippa, Gianluca, Fischer, Marc, Frank, John, Galvagno, Marta, and Gharun, Mana

Abstract

The FLUXNET2015 dataset provides ecosystem-scale data on CO2, water, and energy exchange between the biosphere and the atmosphere, and other meteorological and biological measurements, from 212 sites around the globe (over 1500 site-years, up to and including year 2014). These sites, independently managed and operated, voluntarily contributed their data to create global datasets. Data were quality controlled and processed using uniform methods, to improve consistency and intercomparability across sites. The dataset is already being used in a number of applications, including ecophysiology studies, remote sensing studies, and development of ecosystem and Earth system models. FLUXNET2015 includes derived-data products, such as gap-filled time series, ecosystem respiration and photosynthetic uptake estimates, estimation of uncertainties, and metadata about the measurements, presented for the first time in this paper. In addition, 206 of these sites are for the first time distributed under a Creative Commons (CC-BY 4.0) license. This paper details this enhanced dataset and the processing methods, now made available as open-source codes, making the dataset more accessible, transparent, and reproducible.

Published
2020

21. How Life Transitions Influence People’s Use of the Internet: A Clustering Approach

Author

Benvenuti, Martina, Rocha, Humberto, Dimas, Isabel Dórdio, Mazzoni, Elvis, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Misra, Sanjay, editor, Rocha, Ana Maria A. C., editor, and Garau, Chiara, editor

Published
2022
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24. Aged rats learn Morris Water maze using non-spatial search strategies evidenced by a parameter-based algorithm

Author

Villarreal-Silva Eliud Enrique, González-Navarro Alejandro Rafael, Salazar-Ybarra Rodolfo Amador, Quiroga-García Oscar, Cruz-Elizondo Miguel Angel de Jesús, García-García Aracely, Rodríguez-Rocha Humberto, Morales-Gómez Jesús Alberto, Quiroga-Garza Alejandro, Elizondo-Omaña Rodrigo Enrique, de León Ángel Raymundo Martínez-Ponce, and Guzmán-López Santos

Subjects
morris water maze, search strategy, aging, learning, memory, hippocampus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Spatial learning and memory are used by all individuals who need to move in a space. Morris water maze (MWM) is an accepted method for its evaluation in murine models and has many protocols, ranging from the classic parameters of latency, distance, and number of crossings to the platform zone, to other more complex methods involving computerized trajectory analysis. Algorithm-based SS analysis is an alternative that enriches traditional classic parameters. We developed a non-computerized parameter-based Search Strategy Algorithm (SSA), to classify strategies and detect changes in spatial memory and learning. For this, our algorithm was validated using young and aged rats, evaluated by two observers who classified the trajectories of the rats based on the effectiveness, localization, and precision to reach the platform. SSA is classified into 10 categories, classified by effectiveness, initial direction, and precision. Traditional measurements were unable to show significant differences in the learning process. However, significant differences were identified in SSA. Young rats used a direct search strategy (SS), while aged rats preferred indirect ones. The number of platform crossings was the only variable to show the difference in the intermediate probe trial. The parameter-based algorithm represents an alternative to the computerized SS methods to analyze the spatial memory and learning process in young and age rats. We validate the use of SSA as an alternative to computerized SS analysis spatial learning acquisition. We demonstrated that aged rats had the ability to learn spatial memory tasks using different search strategies. The use of SSA resulted in a reliable and reproducible method to analyze MWM protocols.

Published
2022
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27. Assessing Hydrological Response and Resilience of Watersheds as Strategy for Climatic Change Adaptation in Neotropical Region.

Author

Ogasawara, Matheus E. K., Mattos, Eduardo M., Rocha, Humberto R., Wei, Xiaohua, and Ferraz, Silvio F. B.

Abstract

This study aimed to assess the hydrological response and resilience of watersheds in a neotropical region to identify regions sensitive to climate variations, enabling the development of adaptive strategies in response to global environmental changes. This study applied Budyko's framework using Fuh's hydrological model rewritten by Zhou to estimate hydrological response and Budyko's metrics (deviation and elasticity) to estimate hydrological resilience to climatic changes in 26 watersheds in southeastern Brazil. The proposed modeling was able to capture the differences among the watersheds, with "m" values ranging from 1.79 to 3.63. It was possible to rank the hydrological resilience from low to high across watersheds using Budyko's metrics, where the highest values of elasticity were found in watersheds with a higher percentage of forest cover. The sensitive analyses showed that watersheds with higher "m" values are more sensitive to changes in precipitation and potential evapotranspiration. The results also demonstrate that mean elevation and stream density were two key variables that influence the "m" value; these physiographic characteristics may alter the water and energy balance of the watershed affecting the water yield. A relationship between watershed's hydrological response and resilience was proposed to identify critical areas for the stability of water yield in the watersheds, providing a guide for public policy and suggesting ways to help the management of water resources in watersheds. [ABSTRACT FROM AUTHOR]

Published
2024
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28. A Randomized Direct-Search Approach for Beam Angle Optimization in Intensity-Modulated Proton Therapy

Author

Rocha, Humberto, Dias, Joana, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Misra, Sanjay, editor, Garau, Chiara, editor, Blečić, Ivan, editor, Taniar, David, editor, Apduhan, Bernady O., editor, Rocha, Ana Maria A. C., editor, Tarantino, Eufemia, editor, and Torre, Carmelo Maria, editor

Published
2021
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30. Comparison of three techniques for decellularization of porcine bone-tendon-bone grafts

Author

Sepúlveda-García, Jorge Arturo, primary, Martínez-Puente, David Hernán, additional, Ballesteros-Elizondo, Raquel Guadalupe, additional, Rodríguez-Rocha, Humberto, additional, García-García, Aracely, additional, Soto-Domínguez, Adolfo, additional, Saucedo-Cárdenas, Odila, additional, Vilchez-Cavazos, José Félix, additional, Montes de Oca-Luna, Roberto, additional, and Loera-Arias, María de Jesús, additional

Published
2024
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32. Advantage of Beam Angle Optimization in Head-and-Neck IMRT: Patient Specific Analysis

Author

Ventura, Tiago, Lopes, Maria do Carmo, Rocha, Humberto, da Costa Ferreira, Brigida, Dias, Joana, Magjarevic, Ratko, Series Editor, Ładyżyński, Piotr, Associate Editor, Ibrahim, Fatimah, Associate Editor, Lackovic, Igor, Associate Editor, Rock, Emilio Sacristan, Associate Editor, Henriques, Jorge, editor, Neves, Nuno, editor, and de Carvalho, Paulo, editor

Published
2020
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33. Dose-Response to Different Radiochemotherapy Regimens in Locally Advanced Pancreatic Cancer

Author

Ferreira, Brígida C., Dias, Joana, Gomes, Adriana, Mavroidis, Panayiotis, Rocha, Humberto, Magjarevic, Ratko, Series Editor, Ładyżyński, Piotr, Associate Editor, Ibrahim, Fatimah, Associate Editor, Lackovic, Igor, Associate Editor, Rock, Emilio Sacristan, Associate Editor, Henriques, Jorge, editor, Neves, Nuno, editor, and de Carvalho, Paulo, editor

Published
2020
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35. Comparison of Different Strategies for Arc Therapy Optimization

Author

Rocha, Humberto, Dias, Joana, Carrasqueira, Pedro, Ventura, Tiago, Ferreira, Brígida, Lopes, Maria do Carmo, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Misra, Sanjay, editor, Garau, Chiara, editor, Blečić, Ivan, editor, Taniar, David, editor, Apduhan, Bernady O., editor, Rocha, Ana Maria A. C., editor, Tarantino, Eufemia, editor, Torre, Carmelo Maria, editor, and Karaca, Yeliz, editor

Published
2020
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39. Copper Induces Damage, Oxidative Stress and Cell Death in Endothelium of Chronic Intoxicated Wistar Rats/El Cobre Induce Dano, Estres Oxidativo y Muerte Celular en el Endotelio de Ratas Wistar Intoxicadas

Author

Fernandez-Rodarte, Bernardo A., Soto-Dominguez, Adolfo, Gonzalez-Navarro, Alejandro, Mellado-Ayala, Maximiliano, Pina-Mendoza, Edgar I., Rodriguez-Rocha, Humberto, Montes-de-Oca-Luna, Roberto, Guerra-Leal, Jesus D., Guzman-Lopez, Santos, and Elizondo-Omana, Rodrigo E.

Published
2022

41. Interannual Variability of Water and Heat Fluxes in a Woodland Savanna (Cerrado) in Southeastern Brazil: Effects of Severe Drought and Soil Moisture.

Author

da Conceição, Lucas F. C., da Rocha, Humberto R., Navarrete, Nelson V., Rosolem, Rafael, Cabral, Osvaldo M. R., and de Freitas, Helber C.

Subjects
*CERRADOS, *SOIL moisture, *HEAT flux, *COSMIC rays, *FORESTS & forestry, *SAVANNAS, *BIOMES, *DROUGHTS
Abstract

The Brazilian Cerrado biome is known for its high biodiversity, and the role of groundwater recharge and climate regulation. Anthropogenic influence has harmed the biome, emphasizing the need for science to understand its response to climate and reconcile economic exploration with preservation. Our work aimed to evaluate the seasonal and interannual variability of the surface energy balance in a woodland savanna (Cerrado) ecosystem in southeastern Brazil over a period of 19 years, from 2001 to 2019. Using field micrometeorological measurements, we examined the variation in soil moisture and studied its impact on the temporal pattern of energy fluxes to distinguish the effects during rainy years compared to a severe drought spell. The soil moisture measures used two independent instruments, cosmic ray neutron sensor CRNS, and FDR at different depths. The measures were taken at the Pé de Gigante (PEG) site, in a region of well-defined seasonality with the dry season in winter and a hot/humid season in summer. We gap-filled the energy flux measurements with a calibrated biophysical model (SiB2). The long-term averages for air temperature and precipitation were 22.5 °C and 1309 mm/year, respectively. The net radiation (Rn) was 142 W/m2, the evapotranspiration (ET) and sensible heat flux (H) were 3.4 mm/d and 52 W/m2, respectively. Soil moisture was marked by a pronounced negative anomaly in the 2014 year, which caused an increase in the Bowen ratio and a decrease in Evaporative fraction, that lasted until the following year 2015 during the dry season, despite the severe meteorological drought of 2013/2014 already ending, which was corroborated by the two independent measurements. The results showed the remarkable influence of precipitation and soil moisture on the interannual variability of the energy balance in this Cerrado ecosystem, aiding in understanding how it responds to strong climate disturbances. [ABSTRACT FROM AUTHOR]

Published
2024
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43. An Optimization Approach for Noncoplanar Intensity-Modulated Arc Therapy Trajectories

Author

Rocha, Humberto, Dias, Joana, Ventura, Tiago, Ferreira, Brígida, do Carmo Lopes, Maria, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Misra, Sanjay, editor, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Stankova, Elena, editor, Korkhov, Vladimir, editor, Torre, Carmelo, editor, Rocha, Ana Maria A.C., editor, Taniar, David, editor, Apduhan, Bernady O., editor, and Tarantino, Eufemia, editor

Published
2019
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44. Forecasting Wheat Prices Based on Past Behavior: Comparison of Different Modelling Approaches

Author

Dias, Joana, Rocha, Humberto, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Misra, Sanjay, editor, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Stankova, Elena, editor, Korkhov, Vladimir, editor, Torre, Carmelo, editor, Rocha, Ana Maria A.C., editor, Taniar, David, editor, Apduhan, Bernady O., editor, and Tarantino, Eufemia, editor

Published
2019
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45. A Nonlinear Dynamical System Perspective on Team Learning: The Role of Team Culture and Social Cohesion

Author

Dimas, Isabel Dórdio, Rebelo, Teresa, Lourenço, Paulo Renato, Rocha, Humberto, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Misra, Sanjay, editor, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Stankova, Elena, editor, Korkhov, Vladimir, editor, Torre, Carmelo, editor, Rocha, Ana Maria A.C., editor, Taniar, David, editor, Apduhan, Bernady O., editor, and Tarantino, Eufemia, editor

Published
2019
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