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2. Infrastructural Justice for Responsible Software Engineering

Author

Robinson, Dr. Sarah, primary, Buckley, Dr. Jim, additional, Ciolfi, Luigina, additional, Linehan, Dr. Conor, additional, McInerney, Dr. Clare, additional, Nuseibeh, Bashar, additional, Twomey, John, additional, Rauf, Dr. Irum, additional, and McCarthy, John, additional

Published
2024
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8. Androgenic anabolic steroid abuse.

Author

Robinson, Dr Emilia, Haque, Dr Raju, and Eggink, Dr Aline

Abstract

Androgen anabolic steroid abuse is a broad term describing the use of structural derivatives of testosterone with the aim to increase body mass and muscle size, or to enhance athletic performance. These drugs are typically used in large doses, much higher than would be prescribed for the treatment of medical conditions. This use of steroids is illegal and can lead to multiple adverse effects including cardiovascular, hepatic, metabolic and psychological issues. Many patients abusing steroids will not typically disclose this information when presenting to their GP. This article aims to help raise awareness of signs and symptoms of abuse, as well as highlight the common long-term risks and discuss a GP's role in managing these complex scenarios. [ABSTRACT FROM AUTHOR]

Published
2023
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14. Establishment of CORONET; COVID-19 Risk in Oncology Evaluation Tool to identify cancer patients at low versus high risk of severe complications of COVID-19 infection upon presentation to hospital

Author

Donal Landers Dr, Prerana Huddar Dr, Tim Cooksley Dr, Hayley Boyce Dr, Cong Zhou Dr, Hayley McKenzie Dr, Caroline Wilson Dr, Umair T Khan Dr, Jamie Weaver Dr, Anne C Armstrong Dr, Michael Rowe Dr, Kathryn Banfill Dr, Angelos Angelakas Dr, Alec Maynard Dr, Paul Fitzpartick Dr, Joshua Woodcock Dr, Theingi Aung Dr, Anne Thomas Prof, Christina Hague Dr, Rohan Shotton Dr, Donna Graham Dr, Sophie Williams Dr, Sam Khan Dr, Rebecca J Lee Dr, Louise Lever Dr, Roseleen Sheehan Dr, Talvinder Bhogal Dr, Lance Turtle, Caroline Dive Prof, Tim Robinson Dr, Ellen Copson Dr, Richard Hoskins Dr, Hannah Frost Ms, Julie Stevenson Dr, Andre Freitas Dr, Elena Dickens Dr, Leonie Eastlake Dr, Mark Baxter Dr, Laura Horsley Dr, Oskar Wysocki Dr, Fabio Gomes Dr, Michelle Harrison Dr, Zoe Hudson Dr, Alexander J. Stockdale, Ann Tivey Dr, and Carlo Palmieri Prof

Subjects
Oncology, medicine.medical_specialty, Training set, Coronavirus disease 2019 (COVID-19), business.industry, Cancer, medicine.disease, Logistic regression, Internal medicine, Cohort, Hospital admission, medicine, In patient, Presentation (obstetrics), business
Abstract

BackgroundCancer patients are at increased risk of severe COVID-19. As COVID-19 presentation and outcomes are heterogeneous in cancer patients, decision-making tools for hospital admission, severity prediction and increased monitoring for early intervention are critical.ObjectiveTo identify features of COVID-19 in cancer patients predicting severe disease and build a decision-support online tool; COVID-19 Risk in Oncology Evaluation Tool (CORONET)MethodData was obtained for consecutive patients with active cancer with laboratory confirmed COVID-19 presenting in 12 hospitals throughout the United Kingdom (UK). Univariable logistic regression was performed on pre-specified features to assess their association with admission (≥24 hours inpatient), oxygen requirement and death. Multivariable logistic regression and random forest models (RFM) were compared with patients randomly split into training and validation sets. Cost function determined cut-offs were defined for admission/death using RFM. Performance was assessed by sensitivity, specificity and Brier scores (BS). The CORONET model was then assessed in the entire cohort to build the online CORONET tool.ResultsTraining and validation sets comprised 234 and 66 patients respectively with median age 69 (range 19-93), 54% males, 46% females, 71% vs 29% had solid and haematological cancers. The RFM, selected for further development, demonstrated superior performance over logistic regression with AUROC predicting admission (0.85 vs. 0.78) and death (0.76 vs. 0.72). C-reactive protein was the most important feature predicting COVID-19 severity. CORONET cut-offs for admission and mortality of 1.05 and 1.8 were established. In the training set, admission prediction sensitivity and specificity were 94.5% and 44.3% with BS 0.118; mortality sensitivity and specificity were 78.5% and 57.2% with BS 0.364. In the validation set, admission sensitivity and specificity were 90.7% and 42.9% with BS 0.148; mortality sensitivity and specificity were 92.3% and 45.8% with BS 0.442. In the entire cohort, the CORONET decision support tool recommended admission of 99% of patients requiring oxygen and of 99% of patients who died.Conclusions and RelevanceCORONET, a decision support tool validated in hospitals throughout the UK showed promise in aiding decisions regarding admission and predicting COVID-19 severity in patients with cancer presenting to hospital. Future work will validate and refine the tool in further datasets.

Published
2020

21. Abstract PD9-12: Integrative molecular profiling of breast cancer brain metastasis and patient-derived xenograft organoids from resected breast cancer brain metastases to interrogate and prioritize therapeutic personalized strategies

Author

Morikawa, A, primary, Robinson, DR, additional, Soellner, M, additional, Wu, Y-M, additional, Lonigro, R, additional, Gilani, R, additional, Cheng, X, additional, Lachacz, E, additional, Thomas, D, additional, McMurray, K, additional, Smerage, J, additional, Henry, NL, additional, Heth, J, additional, Chinnaiyan, A, additional, Hayes, DF, additional, and Merajver, S, additional

Published
2019
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23. Abstract P2-09-26: Frequency and mechanisms of elevated somatic mutation burden in metastatic breast cancer and response to immune checkpoint blockade

Author

Cobain, EF, primary, Robinson, DR, additional, Wu, Y-M, additional, Lonigro, R, additional, Vats, P, additional, Rabban, E, additional, Kumar-Sinha, C, additional, Schott, AF, additional, Smerage, JB, additional, Morikawa, A, additional, Burness, ML, additional, Van Poznak, CH, additional, Griggs, J, additional, Wicha, M, additional, Hayes, DF, additional, and Chinnaiyan, AM, additional

Published
2018
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26. Abstract P3-05-01: Molecular analysis of cancer tissue, circulating tumor cells (CTC) and cell-free plasma tumor DNA (ptDNA) suggests variable mechanisms of resistance to endocrine therapy (ET) in estrogen receptor (ER) positive metastatic breast cancer (MBC)

Author

Paoletti, C, primary, Aung, K, additional, Cannell, EM, additional, Darga, EP, additional, Chu, D, additional, Kidwell, KM, additional, Thomas, DG, additional, Tokudome, N, additional, Brown, ME, additional, McNutt, LM, additional, Gersch, C, additional, Schott, AF, additional, Park, BH, additional, Robinson, DR, additional, Chinnaiyan, AM, additional, Rae, JM, additional, and Hayes, DF, additional

Published
2016
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27. Abstract P2-02-19: Somatic genetic profiling of circulating tumor cells (CTC) in metastatic breast cancer (MBC) patients

Author

Paoletti, C, primary, Cani, AK, additional, Aung, K, additional, Darga, EP, additional, Cannell, EM, additional, Hovelson, DH, additional, Yazdani, M, additional, Blevins, AR, additional, Tokudome, N, additional, Larios, JM, additional, Thomas, DG, additional, Brown, ME, additional, Gersch, C, additional, Schott, AF, additional, Robinson, DR, additional, Chinnaiyan, AM, additional, Bischoff, F, additional, Hayes, DF, additional, Rae, JM, additional, and Tomlins, SA, additional

Published
2016
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32. Reoperations on the autograft and homograft after the Ross procedure: A report from the German-Dutch Ross registry

Author

Charitos, EI, primary, Hemmer, W, additional, Rein, JG, additional, Takkenberg, J, additional, Bogers, AJJC, additional, Hanke, T, additional, Boehm, JO, additional, Botha, CA, additional, Bechtel, JFM, additional, Erasmi, A, additional, Misfeld, M, additional, Robinson, DR, additional, Lange, R, additional, Hörer, J, additional, Moritz, A, additional, Özaslan, F, additional, Wahlers, T, additional, Franke, UF, additional, Hetzer, R, additional, Hübler, M, additional, Ziemer, G, additional, Graf, B, additional, Ross, DN, additional, Stierle, U, additional, and Sievers, HH, additional

Published
2009
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34. Author Reply

Author

Hackett, Dr Allan, primary, Robinson, Dr Frances, additional, Billington, Professor David, additional, and Stratton, Dr Gareth, additional

Published
2003
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36. Periodic - A Game of The Elements: amply rewards the challenge it presents.

Author

Robinson, Dr Louise and Turner, Dr Ian

Subjects
PERIODIC table of the elements, GAMES, ATOMIC mass
Abstract

The game does take a little while to get to grips with (especially for those not familiar with the subject matter) but is a lot of fun. In Periodic: A Game of The Elements the players undertake a mazy journey across the periodic table using or gaining energy to activate periodic trends. [Extracted from the article]

Published
2022

37. game theory.

Author

Robinson, Dr Louise and Turner investigate…, Dr Ian

Subjects
GAME theory, SPATIAL ability
Abstract

This tactical, tile-laying game will truly test your spatial thinking as you and your gaming companions lay tiles to create a "big idea" and earn prestige points. Although appearing a simple concept on the surface, the tactical play of your tiles is key and you need to consider when and where to play tiles in order to achieve the highest numbei of prestige points. Prestige points are earned by completing inspiration cards or fulfilling the requirements of a major theory card, you also gain prestige points should another player use your tiles to complete their own inspiration card. [Extracted from the article]

Published
2022

38. The influence of HR strategy in the capitalist restructuring of Poland

Author

Robinson, Dr. Izabela

Subjects
Poland -- Economic aspects, Organizational change -- Management, Organizational change -- Research, Human resource planning -- Influence, Human resource planning -- Evaluation, Company business management, Business, Human resources and labor relations
Abstract

The findings of a research project conducted to evaluate the influence of human resource strategy, on the nature and scope of business organizational restructuring process in Poland, after the demolition of social system is discussed.

Published
2006

45. Approach to the patient with chronic hepatitis C infection. (Abstract & Commentary)

Author

Robinson, Dr.

Subjects
Hepatitis C -- Care and treatment, Health
Abstract

Synopsis: Primary care physicians should identify patients with chronic hepatitis C infection, advise them regarding transmission risks, and should assist in treatment decisions. Source: Herrine SK. Ann Intern Med. 2002;136:747-757. [...]

Published
2002

47. game theory: Games are a useful distraction during these times. Dr Louise Robinson and Dr Ian Turner, take us through Carbon City Zero (world edition) to find out if it is any good.

Author

Robinson, Dr Louise and Turner, Dr Ian

Subjects
GAME theory, DISTRACTION, CARBON, CARBON offsetting
Abstract

In this collaborative game, you must work with the other city mayors to battle poor transport, lobby government and replace those high carbon producing factories with more carbon neutral alternatives. As mayors have the same starting hand, repeat games are interesting as mayors subsequently try to replicate strategies. The game also comes with rules for rival mayors (a competitive game) and the lone mayor (solo game). [Extracted from the article]

Published
2021

48. game theory.

Author

Robinson, Dr Louise and Turner, Dr Ian

Subjects
GAME theory, MUTE swan, GREAT tit
Abstract

If you've never purchased a game expansion before then perhaps start wit the European deck which doesn't involve learning about a new food source or using new player mats. Each expansion comes with new bonus cards, eggs, goal tiles and scorepads, the Oceanic expansion also comes with a new food source -- nectar -- as well as accompanying food dice and player mats to use it. Increasing the deck to include birds with new powers and food sources obviously increases the complexity of the game so add one expansion at a time. [Extracted from the article]

Published
2021

50. game theory.

Author

Robinson, Dr Louise and Turner, Dr Ian

Subjects
GAME theory
Published
2020

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