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3. Anti-TNF-α Antibody and Cancer Cachexia

Author

de Witte, Mark, Anderson, Mark, Robinson, Don, Mantovani, Giovanni, editor, Anker, Stefan D., editor, Inui, Akio, editor, Morley, John E., editor, Fanelli, Filippo Rossi, editor, Scevola, Daniele, editor, Schuster, Michael W., editor, and Yeh, Shing-Shing, editor

Published
2006
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6. [11C]-Choline PET/CT-guided simultaneous integrated boost to dominant intraprostatic lesions using intensity-modulated radiation therapy with helical tomotherapy technique for dose escalation

Author

Amanie, John, Hans-Sonke, Jans, Wuest, Melinda, Field, Colin, Pervez, Nadeem, Murtha, Albert, Usmani, Nawaid, Yee, Don, Danielson, Brita, Patel, Samir, Macewan, Rob, Robinson, Don, Wilson, John, Lewis, Dyann, Parliament, Matthew, and McEwan, Alexander J. B.

Published
2015
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13. Bortezomib, thalidomide and dexamethasone, with or without cyclophosphamide, for patients with previously untreated multiple myeloma: 5-year follow-up

Author

Ludwig, Heinz, Greil, Richard, Masszi, Tamas, Spicka, Ivan, Shpilberg, Ofer, Hajek, Roman, Dmoszynska, Anna, Paiva, Bruno, Vidriales, María-Belén, Esteves, Graca, Stoppa, Anne Marie, Robinson, Don, Jr, Chaturvedi, Shalini, Ataman, Ozlem, Enny, Christopher, Feng, Huaibao, van de Velde, Helgi, and Viterbo, Luisa

Published
2015
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23. Convention Reports

Author

Ellis, Howard, Robinson, Don C., Duncan, C. Herbert, Mason, Retha Jane, Miller, Thomas W., Zimmerman, George H., Dailey, James, Rolland, Paul, Alton, Louise M., Fisher, James L., Boyd, Jack, Bray, Bruce, and Matson, Sigfred C.

Published
1966

26. PO26

Author

Wood, Tania, primary, Yang, Fan, additional, Wiebe, Ericka, additional, Cuartero, Julie, additional, Robinson, Don, additional, Huang, Fleur, additional, and Menon, Geetha, additional

Published
2021
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27. Effect of prerequisite on introductory statistics performance

Author

Choudhury, Askar, Robinson, Don, and Radhakrishnan, Ramaswamy

Subjects
High schools -- Curricula, High schools -- Evaluation, Mathematical statistics -- Study and teaching, Business schools -- Management, Company business management, Business, general
Abstract

ABSTRACT Experience in teaching suggests that students' success is greatly affected by the prerequisite courses taken. Statistical Reasoning (introductory statistics) is a required course in most business schools. Students can [...]

Published
2007

32. Analysis and Comparison of Natural Language Processing Algorithms as Applied to Bitcoin Conversations on Social Media.

Author

McMillan, Benjamin, Myers, Joshua, Nguyen, An, Robinson, Don, and Kennard, Mark

Subjects
BITCOIN, NATURAL language processing, SOCIAL media, ALGORITHMS, INVESTMENT management
Abstract

Institutional interest in bitcoin has grown significantly since its "bubble highs" in 2017; and given its lack of traditional fundamentals, investor sentiment is likely to drive price discovery. As social media has grown, Reddit has evolved to host significant conversations regarding bitcoin ('r/bitcoin') and general investing ('r/investing'). We focus on these two channels using four distinct natural language processing algorithms to create an ensemble sentiment score and measure the relationship of the score to the change in bitcoin's price. [ABSTRACT FROM AUTHOR]

Published
2022
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33. New measurement data has implications for quantifying natural gas losses from cast iron distribution mains

Author

Bylin, Carey, Cassab, Luigi, Cazarini, Adilson, Ori, Danilo, Robinson, Don, and Sechler, Doug

Subjects
Consolidated Edison Inc., Pipe lines -- Measurement, Methane -- Measurement, Greenhouse gases -- Measurement, Natural gas -- Measurement, Electric utilities -- Measurement, Hydrocarbons -- Measurement, Cast-iron -- Measurement, Atmospheric carbon dioxide -- Measurement, Iron -- Measurement, Air pollution -- Measurement, Business, Petroleum, energy and mining industries, Measurement
Abstract

The loss of natural gas from oil and natural gas systems is a global environmental concern given that methane, the primary component of natural gas, is a powerful greenhouse gas [...]

Published
2009

39. Near-Term Interstellar Sailing

Author

Matloff, Gregory L, Taylor, Travis, Powell, Conley, Moton, Tryshanda, and Robinson, Don

Subjects
Lunar And Planetary Science And Exploration
Abstract

A number of techniques are investigated that allow the possibility of near- ecliptic exploration beyond the Sun's heliopause (200 AU) using contemporary solar-sail spacecraft (with areal mass thickness about 0.0082 kilograms per square meters). Maximum mission duration to the heliopause was defined as one human working lifetime; missions to the Sun's gravity focus at 550 AU from the sun must take less time than one human lifetime. Options include unfurling the sail at the 0.2-AU perihelion of a parabolic solar orbit, unfurling the sail at the 0.2-AU perihelion of a 2.5-AU aphelion solar orbit, and performing a grazing gravity-assist flyby of Jupiter. Although these techniques are capable of performing the defined mission, higher-technology sails are faster.

Published
2004

40. Solar Sail Application to Comet Nucleus Sample Return

Author

Taylor, Travis S, Moton, Tryshanda T, Robinson, Don, Anding, R. Charles, Matloff, Gregory L, Garbe, Gregory, and Montgomery, Edward

Subjects
Spacecraft Design, Testing And Performance
Abstract

Many comets have perihelions at distances within 1.0 Astronomical Unit (AU) from the sun. These comets typically are inclined out of the ecliptic. We propose that a solar sail spacecraft could be used to increase the inclination of the orbit to match that of these 1.0 AU comets. The solar sail spacecraft would match the orbit velocity for a short period of time, which would be long enough for a container to be injected into the comet's nucleus. The container would be extended from a long durable tether so that the solar sail would not be required to enter into the potentially degrading environment of the comet s atmosphere. Once the container has been filled with sample material, the tether is retracted. The solar sail would then lower its inclination and fly back to Earth for the sample return. In this paper, we describe the selection of cometary targets, the mission design, and the solar sailcraft design suitable for sail-comet rendezvous as well as possible rendezvous scenarios.

Published
2003

43. Symptom burden among patients with Renal Cell Carcinoma (RCC): content for a symptom index

Author

Mahadevia Parthiv J, Robinson Don, Cella David, Harding Gale, Clark Jason, and Revicki Dennis A

Subjects
Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Abstract Background Renal cell carcinoma (RCC) has multiple symptoms stemming from disease and treatments. There are few validated scales for evaluating RCC symptoms. Methods A national cross-sectional study of adult RCC patients was conducted from October to December 2003 to define patient-reported RCC symptomology. Participants were asked open-ended questions regarding their signs and symptoms and completed an 86-item pilot questionnaire of physical and psychological symptoms. Patients were asked to rate the relevancy and clarity of each pilot question using a 5-point Likert scale. Subsequent open-ended caregiver interviews and a provider panel relevance ranking contributed additional information. Results The average age of the participants (n = 31) was 55 years; 55% of patients were male, 74% had attended college, and 97% were Caucasian. The five most frequent symptoms among localized-stage patients (n = 14) were irritability (79%), pain (71%), fatigue (71%), worry (71%), and sleep disturbance (64%). Among metastatic patients (n = 17), the five most frequent symptoms were fatigue (82%), weakness (65%), worry (65%), shortness of breath (53%), and irritability (53%). More than 50% of localized and metastatic-stage patients reported pain, weakness, fatigue, sleep disturbance, urinary frequency, worry, and mood disorders as being moderately to highly relevant. Conclusion A brief, self-administered RCC Symptom Index was created that captures the relevant signs and symptoms of both localized and metastatic patients. Pending additional content validation, the Index can be used to assess the signs and symptoms of RCC and the clinical benefit resulting from RCC treatment.

Published
2007
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44. Bortezomib-based therapy for relapsed/refractory multiple myeloma in real-world medical practice

Author

Terpos, Evangelos, Katodritou, Eirini, de la Rubia, Javier, Hungria, Vania, Hulin, Cyrille, Roussou, Maria, Delforge, Michel, Bries, Greet, Stoppa, Anne-Marie, Aagesen, Jesper, Sargin, Deniz, Belch, Andrew, Ahlberg, Lucia, Diels, Joris, Olie, Robert A., Robinson, Don Jr., Spencer, Mike, Potamianou, Anna, van de Velde, Helgi, Dimopoulos, Meletios A., Terpos, Evangelos, Katodritou, Eirini, de la Rubia, Javier, Hungria, Vania, Hulin, Cyrille, Roussou, Maria, Delforge, Michel, Bries, Greet, Stoppa, Anne-Marie, Aagesen, Jesper, Sargin, Deniz, Belch, Andrew, Ahlberg, Lucia, Diels, Joris, Olie, Robert A., Robinson, Don Jr., Spencer, Mike, Potamianou, Anna, van de Velde, Helgi, and Dimopoulos, Meletios A.

Abstract

Objective: The efficacy and safety of bortezomib-based therapy for relapsed/refractory multiple myeloma (RRMM) in clinical trials may differ from the oncology practice experience. The electronic VELCADE (R) OBservational Study was designed to prospectively evaluate bortezomib for multiple myeloma (MM) in real-world medical practice. Method: Patients scheduled to receive intravenous bortezomib for MM were eligible. The primary objective was to evaluate clinical outcomes, including response, time to response, time to next therapy, treatment-free interval, progression-free survival (PFS), and overall survival (OS). Secondary objectives included safety and healthcare resource utilization. Results: In total, 873 patients with a median of two therapy lines prior to initiating bortezomib were included. The overall response rate (amp;gt;= partial response) was 69%, including 37% complete response/near-complete response. Median time to response was 1.8 months, median time to next therapy was 9.7 months, and median treatment-free interval was 7.9 months. After 22.6 months median follow-up, median PFS was 12.0 months and median OS was 36.1 months. The most common adverse events (AEs) were neuropathy not otherwise specified (19%), diarrhea NOS, and thrombocytopenia (each 17%); 230 (26%) patients discontinued bortezomib due to AEs. Of 689 (79%) patients without baseline peripheral neuropathy (PN), the rate of new-onset any-grade PN increased to 51% (12% grade 3/4) by cycle 8. Overall, 244 (28%) patients were hospitalized, 372 (43%) attended an outpatient visit, and 341 (39%) underwent a diagnostic/therapeutic procedure during bortezomib treatment. Conclusion: These prospective real-world data demonstrate the effectiveness and safety of bortezomib-based therapy for RRMM and confirm high response rates and long OS for this population., Funding Agencies|Janssen Global Services; Millennium Pharmaceuticals, Inc.

Published
2018
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47. Bortezomib retreatment for relapsed and refractory multiple myeloma in real‐world clinical practice

Author

Hulin, Cyrille, primary, de la Rubia, Javier, additional, Dimopoulos, Meletios A., additional, Terpos, Evangelos, additional, Katodritou, Eirini, additional, Hungria, Vania, additional, De Samblanx, Hadewijch, additional, Stoppa, Anne‐Marie, additional, Aagesen, Jesper, additional, Sargin, Deniz, additional, Sioni, Anastasia, additional, Belch, Andrew, additional, Diels, Joris, additional, Olie, Robert A., additional, Robinson, Don, additional, Potamianou, Anna, additional, van de Velde, Helgi, additional, and Delforge, Michel, additional

Published
2018
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49. Bortezomib-based therapy for relapsed/refractory multiple myeloma in real-world medical practice

Author

Terpos, Evangelos, primary, Katodritou, Eirini, additional, de la Rubia, Javier, additional, Hungria, Vania, additional, Hulin, Cyrille, additional, Roussou, Maria, additional, Delforge, Michel, additional, Bries, Greet, additional, Stoppa, Anne-Marie, additional, Aagesen, Jesper, additional, Sargin, Deniz, additional, Belch, Andrew, additional, Ahlberg, Lucia, additional, Diels, Joris, additional, Olie, Robert A., additional, Robinson, Don, additional, Spencer, Mike, additional, Potamianou, Anna, additional, van de Velde, Helgi, additional, and Dimopoulos, Meletios A., additional

Published
2018
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