Search

Your search keyword '"Robinson, Bruce M."' showing total 760 results
Start Over Author "Robinson, Bruce M."
760 results on '"Robinson, Bruce M."'

1. Kidney Function Decline and Serious Adverse Drug Reactions in Patients With CKD

Author

Ayav, Carole, Briançon, Serge, Cannet, Dorothée, Combe, Christian, Fouque, Denis, Frimat, Luc, Herpe, Yves-Edouard, Jacquelinet, Christian, Laville, Maurice, Massy, Ziad A., Pascal, Christophe, Robinson, Bruce M., Stengel, Bénédicte, Lange, Céline, Legrand, Karine, Liabeuf, Sophie, Metzger, Marie, Speyer, Elodie, Hannedouche, Thierry, Moulin, Bruno, Mailliez, Sébastien, Lebrun, Gaétan, Magnant, Eric, Choukroun, Gabriel, Deroure, Benjamin, Lacraz, Adeline, Lambrey, Guy, Philippe, Jean, Bourdenx, Essig, Marie, Lobbedez, Thierry, Azar, Raymond, Sekhri, Hacène, Smati, Mustafa, Jamali, Mohamed, Klein, Alexandre, Delahousse, Michel, Martin, Séverine, Landru, Isabelle, Thervet, Eric, Lang, Philippe, Belenfant, Xavier, Urena, Pablo, Vela, Carlos, Chauveau, Dominique, Panescu, Viktor, Noel, Christian, Glowacki, François, Hoffmann, Maxime, Hourmant, Maryvonne, Besnier, Dominique, Testa, Angelo, Kuentz, François, Zaoui, Philippe, Chazot, Charles, Juillard, Laurent, Burtey, Stéphane, Keller, Adrien, Kamar, Nassim, Laville, Solène M., Gras-Champel, Valérie, Hamroun, Aghilès, Moragny, Julien, Lambert, Oriane, Bieber, Brian, and Alencar De Pinho, Natalia

Published
2024
Full Text
View/download PDF

2. Cardiovascular and Thromboembolic Events in Children and Adults With Glomerular Disease: Findings From the Cure GlomeruloNephropathy (CureGN) Network

Author

Wadhwani, Shikha, Mansfield, Sarah A., Smith, Abigail R., Robinson, Bruce M., Abdelghani, Eman, Al-Uzri, Amira, Ashoor, Isa F., Bartosh, Sharon M., Chishti, Aftab S., Hayek, Salim S., Hladunewich, Michelle A., Kerlin, Bryce A., Madapoosi, Siddharth S., Mariani, Laura H., Mottl, Amy K., Rheault, Michelle N., O’Shaughnessy, Michelle M., Sperati, C. John, Srivastava, Tarak, Selewski, David T., Wang, Chia-shi, Wong, Craig S., Weaver, Donald J., Jr., and Khalid, Myda

Published
2024
Full Text
View/download PDF

3. Association of COVID-19 Versus COVID-19 Vaccination With Kidney Function and Disease Activity in Primary Glomerular Disease: A Report of the Cure Glomerulonephropathy Study

Author

Ahn, Wooin, Appel, Gerald, Appelbaum, Paul, Babayev, Revekka, Chan, Brenda, D’Agati, Vivette Denise, Dogra, Samitri, Fernandez, Hilda, Gharavi, Ali, Hines, William, Husain, Syed Ali, Jain, Namrata, Kiryluk, Krzysztof, Lin, Fangming, Marasa, Maddalena, Markowitz, Glen, Rasouly, Hila Milo, Mohan, Sumit, Mongera, Nicola, Nestor, Jordan, Nickolas, Thomas, Radhakrishnan, Jai, Rao, Maya, Sanna-Cherchi, Simone, Shirazian, Shayan, Stokes, Michael Barry, Uy, Natalie, Valeri, Anthony, Vena, Natalie, Foroncewicz, Bartosz, Moszczuk, Barbara, Mucha, Krzysztof, Perkowska-Ptasińska, Agnieszka, Ghiggeri, Gian Marco, Lugani, Francesca, Ambruzs, Josephine, Liapis, Helen, Baracco, Rossana, Jain, Amrish, Isa Ashoor, Aviles, Diego, Srivastava, Tarak, Ahn, Sun-Young, Devarajan, Prasad, Erkan, Elif, Claes, Donna, Stone, Hillarey, Mason, Sherene, Gbadegesin, Rasheed, Gomez-Mendez, Liliana, Yin, Hong (Julie), Cai, Yi, Jens, Goebel, Steinke, Julia, Weaver, Donald, Lane, Jerome, Cramer, Carl, Pan, Cindy, Paloian, Neil, Sreedharan, Rajasree, Selewski, David, Twombley, Katherine, Bowers, Corinna, Dreher, Mary, Kallash, Mahmoud, Mahan, John, Sharpe, Samantha, Al-Uzri, Amira, Iragorri, Sandra, Belsha, Craig, Alge, Joseph, Braun, Michael, Gomez, A.C., Wenderfer, Scott, Vasylyeva, Tetyana, Feig, Daniel, Fuentes, Gabriel Cara, Hannah, Melisha, Nester, Carla, Chishti, Aftab, Klein, Jon, Katsoufis, Chryso, Seeherunvong, Wacharee, Wong, Craig, Mathews, Nisha, Barcia, John, Swiatecka-Urban, Agnes, Bartosh, Sharon, Hunley, Tracy, Dharnidharka, Vikas, Gaut, Joseph, Laurin, Louis-Philippe, Royal, Virginie, Achanti, Anand, Budisavljevic, Milos, Self, Sally, Ghossein, Cybele, Peleg, Yonatan, Wadhwani, Shikha, Almaani, Salem, Ayoub, Isabelle, Nadasdy, Tibor, Parikh, Samir, Rovin, Brad, Chang, Anthony, Fatima, Huma, Julian, Bruce, Novak, Jan, Renfrow, Matthew, Rizk, Dana, Chen, Dhruti, Derebail, Vimal, Falk, Ronald, Gibson, Keisha, Hogan, Susan, Jain, Koyal, Jennette, J. Charles, Mottl, Amy, Poulton, Caroline, Saha, Manish Kanti, Fogo, Agnes, Sanghani, Neil, Kidd, Jason, Muthusamy, Selvaraj, Hou, Jean, Lemley, Kevin, Mika, Warren, Russo, Pierre, Denburg, Michelle, Kogon, Amy, Meyers, Kevin, Pradhan, Madhura, O’Toole, John, Sedor, John, Sethna, Christine, Vento, Suzanne, Atta, Mohamed, Bagnasco, Serena, Neu, Alicia, Sperati, John, Adler, Sharon, Dai, Tiane, Dukkipati, Ram, Fervenza, Fernando, Sethi, Sanjeev, Kaskel, Frederick, Brathwaite, Kaye, Reidy, Kimberly, Weisstuch, Joseph, Wu, Ming, Zhdanova, Olga, Heymann, Jurgen, Kopp, Jeffrey, Waldman, Meryl, Winkler, Cheryl, Krissberg, Jill, Lafayette, Richard, Fahmeedah, Kamal, Talley, Elizabeth, Hladunewich, Michelle, Parekh, Rulan, Avila-Casado, Carmen, Cattran, Daniel, Heather, Reich, Boll, Philip, Drexler, Yelena, Fornoni, Alessia, Blazius, Brooke, Hodgin, Jeffrey, Oliverio, Andrea, Hogan, Jon, Palmer, Matthew, Abromovitz, Blaise, Mortiz, Michael, Alpers, Charles, Jefferson, J. Ashley, Brown, Elizabeth, Sambandam, Kamal, Roehm, Bethany, Graff, John, Gillespie, Brenda, Kretzler, Matthias, Nast, Cynthia, Barisoni, Laura, Guay-Woodford, Lisa M., Wang, Chia-shi, Glenn, Dorey A., Helmuth, Margaret, Smith, Abigail R., Bomback, Andrew S., Canetta, Pietro A., Coppock, Gaia M., Khalid, Myda, Tuttle, Katherine R., Bou-Matar, Raed, Greenbaum, Larry A., Robinson, Bruce M., Holzman, Lawrence B., Smoyer, William E., Rheault, Michelle N., Gipson, Debbie, and Mariani, Laura H.

Published
2024
Full Text
View/download PDF

4. The Impact of Unmeasured Within- and Between-Cluster Confounding on the Bias of Effect Estimators from Fixed Effect, Mixed effect and Instrumental Variable Models

Author

Li, Yun, Lee, Yoonseok, Port, Friedrich K, and Robinson, Bruce M

Subjects
Statistics - Methodology, Statistics - Applications
Abstract

Instrumental variable methods are popular choices in combating unmeasured confounding to obtain less biased effect estimates. However, we demonstrate that alternative methods may give less biased estimates depending on the nature of unmeasured confounding. Treatment preferences of clusters (e.g., physician practices) are the most f6requently used instruments in instrumental variable analyses (IVA). These preference-based IVAs are usually conducted on data clustered by region, hospital/facility, or physician, where unmeasured confounding often occurs within or between clusters. We aim to quantify the impact of unmeasured confounding on the bias of effect estimators in IVA, as well as alternative methods including ordinary least squares regression, linear mixed models (LMM) and fixed effect models (FE) to study the effect of a continuous exposure (e.g., treatment dose). We derive bias formulae of estimators from these four methods in the presence of unmeasured within- and/or between-cluster confounders. We show that IVAs can provide consistent estimates when unmeasured within-cluster confounding exists, but not when between-cluster confounding exists. On the other hand, FEs and LMMs can provide consistent estimates when unmeasured between-cluster confounding exits, but not for within-cluster confounding. Whether IVAs are advantageous in reducing bias over FEs and LMMs depends on the extent of unmeasured within-cluster confounding relative to between-cluster confounding. Furthermore, the impact of unmeasured between-cluster confounding on IVA estimates is larger than the impact of unmeasured within-cluster confounding on FE and LMM estimates. We illustrate these methods through data applications. Our findings provide guidance for choosing appropriate methods to combat the dominant types of unmeasured confounders and help interpret statistical results in the context of unmeasured confounding

Published
2020

10. Effectiveness and Tolerance of Renin-Angiotensin System Inhibitors With Aging in Chronic Kidney Disease

Author

Ayav, Carole, Briançon, Serge, Cannet, Dorothée, Combe, Christian, Fouque, Denis, Frimat, Luc, Herpe, Yves-Edouard, Jacquelinet, Christian, Laville, Maurice, Massy, Ziad A., Pascal, Christophe, Robinson, Bruce M., Stengel, Bénédicte, Lange, Céline, Legrand, Karine, Liabeuf, Sophie, Metzger, Marie, Speyer, Elodie, Hannedouche, Thierry, Moulin, Bruno, Mailliez, Sébastien, Lebrun, Gaétan, Magnant, Eric, Choukroun, Gabriel, Deroure, Benjamin, Lacraz, Adeline, Lambrey, Guy, Bourdenx, Jean Philippe, Essig, Marie, Lobbedez, Thierry, Azar, Raymond, Sekhri, Hacène, Smati, Mustafa, Jamali, Mohamed, Klein, Alexandre, Delahousse, Michel, Martin, Séverine, Landru, Isabelle, Thervet, Eric, Lang, Philippe, Belenfant, Xavier, Urena, Pablo, Vela, Carlos, Chauveau, Dominique, Panescu, Viktor, Noel, Christian, Glowacki, François, Hoffmann, Maxime, Hourmant, Maryvonne, Besnier, Dominique, Testa, Angelo, Kuentz, François, Zaoui, Philippe, Chazot, Charles, Juillard, Laurent, Burtey, Stéphane, Keller, Adrien, Kamar, Nassim, Villain, Cédric, Hamroun, Aghilès, Laville, Solene, Mansencal, Nicolas, and Pecoits-Filho, Roberto

Published
2022
Full Text
View/download PDF

15. Potential Surrogate Outcomes for Kidney Failure in Advanced CKD: Evaluation of Power and Predictive Ability in CKDopps

Author

Combe, Christian, Duttlinger, Johannes, Fliser, Danilo, Jacquelinet, Christian, Lonnemann, Gerhard, Lopes, Antonio, Massy, Ziad, Pecoits-Filho, Roberto, Reichel, Helmut, Stengel, Bénédicte, Wada, Takashi, Yamagata, Kunihiro, Zee, Jarcy, Muenz, Daniel, McCullough, Keith P., Bieber, Brian, Metzger, Marie, Alencar de Pinho, Natalia, Lopes, Antonio A., Robinson, Bruce M., Young, Eric, and Pisoni, Ronald L.

Published
2022
Full Text
View/download PDF

17. Improving the prognosis of patients with severely decreased glomerular filtration rate (CKD G4+): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Eckardt, Kai-Uwe, Bansal, Nisha, Coresh, Josef, Evans, Marie, Grams, Morgan E, Herzog, Charles A, James, Matthew T, Heerspink, Hiddo JL, Pollock, Carol A, Stevens, Paul E, Tamura, Manjula Kurella, Tonelli, Marcello A, Wheeler, David C, Winkelmayer, Wolfgang C, Cheung, Michael, Hemmelgarn, Brenda R, Participants, Conference, Abu-Alfa, Ali K, Anand, Shuchi, Arici, Mustafa, Ballew, Shoshana H, Block, Geoffrey A, Burgos-Calderon, Rafael, Charytan, David M, Das-Gupta, Zofia, Dwyer, Jamie P, Fliser, Danilo, Froissart, Marc, Gill, John S, Griffith, Kathryn E, Harris, David C, Huffman, Kate, Inker, Lesley A, Jager, Kitty J, Jun, Min, Kalantar-Zadeh, Kamyar, Kasiske, Bertrand L, Kovesdy, Csaba P, Krane, Vera, Lamb, Edmund J, Lerma, Edgar V, Levey, Andrew S, Levin, Adeera, Mauro, Juan Carlos Julián, Nash, Danielle M, Navaneethan, Sankar D, O’Donoghue, Donal, Obrador, Gregorio T, Pecoits-Filho, Roberto, Robinson, Bruce M, Schäffner, Elke, Segev, Dorry L, Stengel, Bénédicte, Stenvinkel, Peter, Tangri, Navdeep, Tentori, Francesca, Tsukamoto, Yusuke, Turakhia, Mintu P, Vazquez, Miguel A, Wang, Angela Yee-Moon, and Williams, Amy W

Subjects
Heart Disease, Cardiovascular, Clinical Research, Kidney Disease, Management of diseases and conditions, 7.3 Management and decision making, Renal and urogenital, Good Health and Well Being, Clinical Decision-Making, Consensus, Evidence-Based Medicine, Glomerular Filtration Rate, Humans, Kidney, Nephrology, Prognosis, Renal Insufficiency, Chronic, Risk Factors, Severity of Illness Index, chronic kidney disease, kidney failure, prediction, prognosis, progression, supportive care, Conference Participants, Clinical Sciences, Urology & Nephrology
Abstract

Patients with severely decreased glomerular filtration rate (GFR) (i.e., chronic kidney disease [CKD] G4+) are at increased risk for kidney failure, cardiovascular disease (CVD) events (including heart failure), and death. However, little is known about the variability of outcomes and optimal therapeutic strategies, including initiation of kidney replacement therapy (KRT). Kidney Disease: Improving Global Outcomes (KDIGO) organized a Controversies Conference with an international expert group in December 2016 to address this gap in knowledge. In collaboration with the CKD Prognosis Consortium (CKD-PC) a global meta-analysis of cohort studies (n = 264,515 individuals with CKD G4+) was conducted to better understand the timing of clinical outcomes in patients with CKD G4+ and risk factors for different outcomes. The results confirmed the prognostic value of traditional CVD risk factors in individuals with severely decreased GFR, although the risk estimates vary for kidney and CVD outcomes. A 2- and 4-year model of the probability and timing of kidney failure requiring KRT was also developed. The implications of these findings for patient management were discussed in the context of published evidence under 4 key themes: management of CKD G4+, diagnostic and therapeutic challenges of heart failure, shared decision-making, and optimization of clinical trials in CKD G4+ patients. Participants concluded that variable prognosis of patients with advanced CKD mandates individualized, risk-based management, factoring in competing risks and patient preferences.

Published
2018

18. Worldwide Early Impact of COVID-19 on Dialysis Patients and Staff and Lessons Learned: A DOPPS Roundtable Discussion

Author

Robinson, Bruce M., Guedes, Murilo, Alghonaim, Mohammed, Cases, Aleix, Dasgupta, Indranil, Gan, Liangying, Jacobson, Stefan H., Kanjanabuch, Talerngsak, Kim, Yong-Lim, Kleophas, Werner, Labriola, Laura, Perlman, Rachel L., Reboldi, Gianpaolo, Srivatana, Vesh, Suri, Rita S., Tsuruya, Kazuhiko, Torres, Pablo Urena, Pisoni, Ronald L., and Pecoits-Filho, Roberto

Published
2021
Full Text
View/download PDF

20. Improving data quality in observational research studies: Report of the Cure Glomerulonephropathy (CureGN) network

Author

Gillespie, Brenda W., Laurin, Louis-Philippe, Zinsser, Dawn, Lafayette, Richard, Marasa, Maddalena, Wenderfer, Scott E., Vento, Suzanne, Poulton, Caroline, Barisoni, Laura, Zee, Jarcy, Helmuth, Margaret, Lugani, Francesca, Kamel, Margret, Hill-Callahan, Peg, Hewitt, Stephen M., Mariani, Laura H., Smoyer, William E., Greenbaum, Larry A., Gipson, Debbie S., Robinson, Bruce M., Gharavi, Ali G., Guay-Woodford, Lisa M., and Trachtman, Howard

Published
2021
Full Text
View/download PDF

21. Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

Author

Abu-Alfa, Ali K., Afsar, Baris, Pai, Amy Barton, Besarab, Anatole, Moore, Geraldine Biddle, Casadevall, Nicole, Cases, Aleix, de Francisco, Angel, Eckardt, Kai-Uwe, Fishbane, Steven, Fried, Linda F., Ganz, Tomas, Ginzburg, Yelena Z., Gómez, Rafael, Goodnough, Lawrence T., Hamano, Takayuki, Hanudel, Mark R., Hao, Chuan-Ming, Iseki, Kunitoshi, Ix, Joachim H., Johansen, Kirsten L., Ketteler, Markus, Kovesdy, Csaba P., Leaf, David E., Macdougall, Iain C., Massy, Ziad A., McMahon, Lawrence P., Minutolo, Roberto, Nakanishi, Takeshi, Nemeth, Elizabeta, Obrador, Gregorio T., Parfrey, Patrick S., Park, Hyeong-Cheon, Pecoits-Filho, Roberto, Robinson, Bruce M., Roger, Simon D., Shah, Yatrik M., Spinowitz, Bruce S., Tanaka, Tetsuhiro, Tsukamoto, Yusuke, Tungsanga, Kriang, Walther, Carl P., Yee-Moon Wang, Angela, Wolf, Myles, Babitt, Jodie L., Eisenga, Michele F., Haase, Volker H., Kshirsagar, Abhijit V., Levin, Adeera, Locatelli, Francesco, Małyszko, Jolanta, Swinkels, Dorine W., Tarng, Der-Cherng, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C., and Drüeke, Tilman B.

Published
2021
Full Text
View/download PDF

22. Adherence to the Kidney Disease: Improving Global Outcomes CKD Guideline in Nephrology Practice Across Countries

Author

Lopes, Antonio, Pecoits-Filho, Roberto, Combe, Christian, Jacquelinet, Christian, Massy, Ziad, Stengel, Bénédicte, Duttlinger, Johannes, Fliser, Danilo, Lonnemann, Gerhard, Reichel, Helmut, Wada, Takashi, Yamagata, Kunihiro, Pisoni, Ron, Robinson, Bruce, Calice da Silva, Viviane, Sesso, Ricardo, Speyer, Elodie, Asahi, Koichi, Hoshino, Junichi, Narita, Ichiei, Perlman, Rachel, Port, Friedrich, Sukul, Nidhi, Wong, Michelle, Young, Eric, Zee, Jarcy, Muenz, Daniel, Tu, Charlotte, Alencar de Pinho, Natalia, Massy, Ziad A., Lopes, Antonio A., Jadoul, Michel, Winkelmayer, Wolfgang C., Pisoni, Ronald L., and Robinson, Bruce M.

Published
2021
Full Text
View/download PDF

24. Longitudinal Changes in Health-Related Quality of Life in Primary Glomerular Disease: Results From the CureGN Study

Author

Gharavi, Ali, Ahn, Wooin, Appel, Gerald B., Avasare, Rupali S., Babayev, Revekka, Batal, Ibrahim, Bomback, Andrew S., Brown, Eric, Campenot, Eric S., Canetta, Pietro, Chan, Brenda, D’Agati, Vivette D., Fernandez, Hilda, Foroncewicz, Bartosz, Ghiggeri, Gian Marco, Hines, William H., Jain, Namrata G., Kiryluk, Krzysztof, Lin, Fangming, Lugani, Francesca, Marasa, Maddalena, Markowitz, Glen, Mohan, Sumit, Mucha, Krzysztof, Nickolas, Thomas L., Radhakrishnan, Jai, Rao, Maya K., Regunathan-Shenk, Renu, Sanna-Cherchi, Simone, Santoriello, Dominick, Stokes, Michael B., Yu, Natalie, Valeri, Anthony M., Zviti, Ronald, Greenbaum, Larry A., Smoyer, William E., Al-Uzri, Amira, Ashoor, Isa, Aviles, Diego, Baracco, Rossana, Barcia, John, Bartosh, Sharon, Belsha, Craig, Braun, Michael C., Chishti, Aftab, Claes, Donna, Cramer, Carl, Davis, Keefe, Erkan, Elif, Feig, Daniel, Freundlich, Michael, Hanna, Melisha, Hidalgo, Guillermo, Jain, Amrish, Khalid, Myda, Kallash, Mahmoud, Lane, Jerome C., Mahan, John, Mathews, Nisha, Nester, Carla, Pan, Cynthia, Patel, Hiren, Revell, Adelaide, Sreedharan, Rajasree, Steinke, Julia, Wenderfer, Scott E., Wong, Craig S., Falk, Ronald, Cook, William, Derebail, Vimal, Fogo, Agnes, Gasim, Adil, Gehr, Todd, Harris, Raymond, Kidd, Jason, Laurin, Louis-Philippe, Pendergraft, Will, Pichette, Vincent, Powell, Thomas Brian, Renfrow, Matthew B., Royal, Virginie, Holzman, Lawrence B., Adler, Sharon, Alpers, Charles, Matar, Raed Bou, Brown, Elizabeth, Choi, Michael, Dell, Katherine M., Dukkipati, Ram, Fervenza, Fernando C., Fornoni, Alessia, Gadegbeku, Crystal, Gipson, Patrick, Hasely, Leah, Hingorani, Sangeeta, Hladunewich, Michelle A., Hogan, Jonathan, Jefferson, J. Ashley, Jhaveri, Kenar, Johnstone, Duncan B., Kaskel, Frederick, Kogan, Amy, Kopp, Jeffrey, Lemley, Kevin V., Dieguez, Laura Malaga, Meyers, Kevin, Neu, Alicia, O'Shaughnessy, Michelle Marie, O’Toole, John F., Parekh, Rulan, Reich, Heather, Reidy, Kimberly, Rondon, Helbert, Sambandam, Kamalanathan K., Sedor, John R., Selewski, David T., Sethna, Christine B., Schelling, Jeffrey, Sperati, John C., Swiatecka-Urban, Agnes, Trachtman, Howard, Tuttle, Katherine R., Weisstuch, Joseph, Zhdanova, Olga, Gillespie, Brenda, Gipson, Debbie S., Herreshoff, Emily, Kretzler, Matthias, Robinson, Bruce M., Mariani, Laura, Troost, Jonathan P., Wladkowski, Matthew, Guay-Woodford, Lisa M., Murphy, Shannon L., Mahan, John D., Srivastava, Tarak, Kogon, Amy J., Cai, Yi, Davis, T. Keefe, Gbadegesin, Rasheed A., Canetta, Pietro A., Nachman, Patrick H., Reeve, Bryce B., Wang, Chia-shi, and Bartosh, Sharon M.

Published
2020
Full Text
View/download PDF

25. Associations of Hemoglobin Levels With Health-Related Quality of Life, Physical Activity, and Clinical Outcomes in Persons With Stage 3-5 Nondialysis CKD

Author

Lopes, Antonio, Pecoits-Filho, Roberto, Combe, Christian, Jacquelinet, Christian, Massy, Ziad, Stengel, Benedicte, Duttlinger, Johannes, Fliser, Danilo, Lonnemann, Gerhard, Reichel, Helmut, Wada, Takashi, Yamagata, Kunihiro, Pisoni, Ron, Robinson, Bruce, Calice da Silva, Viviane, Sesso, Ricardo, Speyer, Elodie, Asahi, Koichi, Hoshino, Junichi, Narita, Ichiei, Perlman, Rachel, Port, Friedrich, Sukul, Nidhi, Wong, Michelle, Young, Eric, Zee, Jarcy, Muenz, Daniel, Guedes, Murilo, Lopes, Antonio A., van Haalen, Heleen, James, Glen, Dhalwani, Nafeesa, Bieber, Brian, Robinson, Bruce M., and Pisoni, Ronald L.

Published
2020
Full Text
View/download PDF

27. Urinary Sodium-to-Potassium Ratio and Blood Pressure in CKD

Author

Hannedouche, Thierry, Moulin, Bruno, Mailliez, Sébastien, Lebrun, Gaétan, Magnant, Eric, Choukroun, Gabriel, Deroure, Benjamin, Lacraz, Adeline, Lambrey, Guy, Bourdenx, Jean Philippe, Essig, Marie, Lobbedez, Thierry, Azar, Raymond, Sekhri, Hacène, Smati, Mustafa, Jamali, Mohamed, Klein, Alexandre, Delahousse, Michel, Combe, Christian, Martin, Séverine, Landru, Isabelle, Thervet, Eric, Massy, Ziad A., Lang, Philippe, Belenfant, Xavier, Urena, Pablo, Vela, Carlos, Frimat, Luc, Chauveau, Dominique, Panescu, Viktor, Noel, Christian, Glowacki, François, Hoffmann, Maxime, Hourmant, Maryvonne, Besnier, Dominique, Testa, Angelo, Kuentz, François, Zaoui, Philippe, Chazot, Charles, Juillard, Laurent, Burtey, Stéphane, Keller, Adrien, Kamar, Nassim, Fouque, Denis, Laville, Maurice, Alencar de Pinho, Natalia, Kaboré, Jean, Metzger, Marie, Lange, Céline, Jacquelinet, Christian, Ayav, Carol, Robinson, Bruce M., Drueke, Tilman, and Stengel, Bénédicte

Published
2020
Full Text
View/download PDF

29. Kidney Function Decline and Serious Adverse Drug Reactions in Patients With CKD

Author

Laville, Solène M., primary, Gras-Champel, Valérie, additional, Hamroun, Aghilès, additional, Moragny, Julien, additional, Lambert, Oriane, additional, Metzger, Marie, additional, Jacquelinet, Christian, additional, Combe, Christian, additional, Fouque, Denis, additional, Laville, Maurice, additional, Frimat, Luc, additional, Robinson, Bruce M., additional, Bieber, Brian, additional, Stengel, Bénédicte, additional, De Pinho, Natalia Alencar, additional, Massy, Ziad A., additional, Liabeuf, Sophie, additional, Ayav, Carole, additional, Briançon, Serge, additional, Cannet, Dorothée, additional, Herpe, Yves-Edouard, additional, Pascal, Christophe, additional, Lange, Céline, additional, Legrand, Karine, additional, and Speyer, Elodie, additional

Published
2023
Full Text
View/download PDF

30. Understanding the Recent Increase in Ferritin Levels in United States Dialysis Patients: Potential Impact of Changes in Intravenous Iron and Erythropoiesis-Stimulating Agent Dosing

Author

Karaboyas, Angelo, Zee, Jarcy, Morgenstern, Hal, Nolen, Jacqueline G, Hakim, Raymond, Kalantar-Zadeh, Kamyar, Zager, Philip, Pisoni, Ronald L, Port, Friedrich K, and Robinson, Bruce M

Subjects
Clinical Research, Hematology, Administration, Intravenous, Aged, Anemia, Drug Labeling, Female, Ferritins, Health Policy, Hematinics, Hemoglobins, Humans, Iron, Male, Middle Aged, Patient Care Bundles, Prospective Studies, Renal Dialysis, United States, anemia, chronic kidney disease, dialysis, epoetin, erythropoietin, Clinical Sciences, Urology & Nephrology
Abstract

Background and objectivesAnemia management changed substantially among dialysis patients in the United States around the time of implementation of the new Centers for Medicare & Medicaid Services bundled payment system and erythropoiesis-stimulating agent (ESA) label change in 2011. Among these, average ferritin levels increased dramatically and have remained high since; this study sought to gain understanding of this sustained rise in ferritin levels.Design, setting, participants, & measurementsTrends in mean ferritin, hemoglobin, IV iron dose, and ESA dose from 2009 to 2013 were examined in 9735 patients from 91 United States Dialysis Outcomes and Practice Patterns Study facilities. Linear mixed models were used to assess the extent to which intravenous (IV) iron and ESA dose accounted for patients' changes in ferritin over time.ResultsMean ESA dose and hemoglobin levels declined throughout the study. Mean IV iron dose increased from 210 mg/mo in 2009-2010 to a peak of 280 mg/mo in 2011, then declined back to 200 mg/mo and remained stable from 2012 to 2013. Mean ferritin increased from 601 ng/ml in the third quarter of 2009 to 887 ng/ml in the first quarter of 2012; models suggest that higher IV iron dosing was a primary determinant during 2011, but lower ESA doses contributed to the sustained high ferritin levels thereafter. In a subset of 17 facilities that decreased IV iron dose in 2011, mean ferritin rose by 120 ng/ml to 764 ng/ml, which appeared to be primarily due to ESA reduction. Together, changes in IV iron and ESA doses accounted for 46% of the increase in ferritin over the study period.ConclusionsIn contrast to expectations, the rise in average IV iron dose did not persist beyond 2011. The sustained rise in ferritin levels in United States dialysis patients after policy changes in 2011, to average levels well in excess of 800 ng/ml, appeared to be partly due to reductions in ESA dosing and not solely IV iron dosing practices. The effect of these changes in ferritin on health outcomes requires further investigation.

Published
2015

35. Association of COVID-19 Versus COVID-19 Vaccination With Kidney Function and Disease Activity in Primary Glomerular Disease: A Report of the Cure Glomerulonephropathy Study

Author

Wang, Chia-shi, primary, Glenn, Dorey A., additional, Helmuth, Margaret, additional, Smith, Abigail R., additional, Bomback, Andrew S., additional, Canetta, Pietro A., additional, Coppock, Gaia M., additional, Khalid, Myda, additional, Tuttle, Katherine R., additional, Bou-Matar, Raed, additional, Greenbaum, Larry A., additional, Robinson, Bruce M., additional, Holzman, Lawrence B., additional, Smoyer, William E., additional, Rheault, Michelle N., additional, Gipson, Debbie, additional, Mariani, Laura H., additional, Ahn, Wooin, additional, Appel, Gerald, additional, Appelbaum, Paul, additional, Babayev, Revekka, additional, Chan, Brenda, additional, D'Agati, Vivette Denise, additional, Dogra, Samitri, additional, Fernandez, Hilda, additional, Gharavi, Ali, additional, Hines, William, additional, Husain, Syed Ali, additional, Jain, Namrata, additional, Kiryluk, Krzysztof, additional, Lin, Fangming, additional, Marasa, Maddalena, additional, Markowitz, Glen, additional, Rasouly, Hila Milo, additional, Mohan, Sumit, additional, Mongera, Nicola, additional, Nestor, Jordan, additional, Nickolas, Thomas, additional, Radhakrishnan, Jai, additional, Rao, Maya, additional, Sanna-Cherchi, Simone, additional, Shirazian, Shayan, additional, Stokes, Michael Barry, additional, Uy, Natalie, additional, Valeri, Anthony, additional, Vena, Natalie, additional, Foroncewicz, Bartosz, additional, Moszczuk, Barbara, additional, Mucha, Krzysztof, additional, Perkowska-Ptasińska, Agnieszka, additional, Ghiggeri, Gian Marco, additional, Lugani, Francesca, additional, Ambruzs, Josephine, additional, Liapis, Helen, additional, Baracco, Rossana, additional, Jain, Amrish, additional, Ashoor, Isa, additional, Aviles, Diego, additional, Srivastava, Tarak, additional, Ahn, Sun-Young, additional, Devarajan, Prasad, additional, Erkan, Elif, additional, Claes, Donna, additional, Stone, Hillarey, additional, Mason, Sherene, additional, Gbadegesin, Rasheed, additional, Gomez-Mendez, Liliana, additional, Yin, Hong (Julie), additional, Cai, Yi, additional, Jens, Goebel, additional, Steinke, Julia, additional, Weaver, Donald, additional, Lane, Jerome, additional, Cramer, Carl, additional, Pan, Cindy, additional, Paloian, Neil, additional, Sreedharan, Rajasree, additional, Selewski, David, additional, Twombley, Katherine, additional, Bowers, Corinna, additional, Dreher, Mary, additional, Kallash, Mahmoud, additional, Mahan, John, additional, Sharpe, Samantha, additional, Al-Uzri, Amira, additional, Iragorri, Sandra, additional, Belsha, Craig, additional, Alge, Joseph, additional, Braun, Michael, additional, Gomez, A.C., additional, Wenderfer, Scott, additional, Vasylyeva, Tetyana, additional, Feig, Daniel, additional, Fuentes, Gabriel Cara, additional, Hannah, Melisha, additional, Nester, Carla, additional, Chishti, Aftab, additional, Klein, Jon, additional, Katsoufis, Chryso, additional, Seeherunvong, Wacharee, additional, Wong, Craig, additional, Mathews, Nisha, additional, Barcia, John, additional, Swiatecka-Urban, Agnes, additional, Bartosh, Sharon, additional, Hunley, Tracy, additional, Dharnidharka, Vikas, additional, Gaut, Joseph, additional, Laurin, Louis-Philippe, additional, Royal, Virginie, additional, Achanti, Anand, additional, Budisavljevic, Milos, additional, Self, Sally, additional, Ghossein, Cybele, additional, Peleg, Yonatan, additional, Wadhwani, Shikha, additional, Almaani, Salem, additional, Ayoub, Isabelle, additional, Nadasdy, Tibor, additional, Parikh, Samir, additional, Rovin, Brad, additional, Chang, Anthony, additional, Fatima, Huma, additional, Julian, Bruce, additional, Novak, Jan, additional, Renfrow, Matthew, additional, Rizk, Dana, additional, Chen, Dhruti, additional, Derebail, Vimal, additional, Falk, Ronald, additional, Gibson, Keisha, additional, Hogan, Susan, additional, Jain, Koyal, additional, Jennette, J. Charles, additional, Mottl, Amy, additional, Poulton, Caroline, additional, Saha, Manish Kanti, additional, Fogo, Agnes, additional, Sanghani, Neil, additional, Kidd, Jason, additional, Muthusamy, Selvaraj, additional, Schelling, Jeffrey, additional, Hou, Jean, additional, Lemley, Kevin, additional, Mika, Warren, additional, Russo, Pierre, additional, Denburg, Michelle, additional, Kogon, Amy, additional, Meyers, Kevin, additional, Pradhan, Madhura, additional, O'Toole, John, additional, Sedor, John, additional, Sethna, Christine, additional, Vento, Suzanne, additional, Atta, Mohamed, additional, Bagnasco, Serena, additional, Neu, Alicia, additional, Sperati, John, additional, Adler, Sharon, additional, Dai, Tiane, additional, Dukkipati, Ram, additional, Fervenza, Fernando, additional, Sethi, Sanjeev, additional, Kaskel, Frederick, additional, Brathwaite, Kaye, additional, Reidy, Kimberly, additional, Weisstuch, Joseph, additional, Wu, Ming, additional, Zhdanova, Olga, additional, Heymann, Jurgen, additional, Kopp, Jeffrey, additional, Waldman, Meryl, additional, Winkler, Cheryl, additional, Krissberg, Jill, additional, Lafayette, Richard, additional, Fahmeedah, Kamal, additional, Talley, Elizabeth, additional, Hladunewich, Michelle, additional, Parekh, Rulan, additional, Avila-Casado, Carmen, additional, Cattran, Daniel, additional, Heather, Reich, additional, Boll, Philip, additional, Drexler, Yelena, additional, Fornoni, Alessia, additional, Blazius, Brooke, additional, Hodgin, Jeffrey, additional, Oliverio, Andrea, additional, Hogan, Jon, additional, Palmer, Matthew, additional, Abromovitz, Blaise, additional, Mortiz, Michael, additional, Alpers, Charles, additional, Jefferson, J. Ashley, additional, Brown, Elizabeth, additional, Sambandam, Kamal, additional, Roehm, Bethany, additional, Graff, John, additional, Nast, Cynthia, additional, Barisoni, Laura, additional, Gillespie, Brenda, additional, and Kretzler, Matthias, additional

Published
2023
Full Text
View/download PDF

36. Significance of Interdialytic Weight Gain versus Chronic Volume Overload: Consensus Opinion

Author

Hecking, Manfred, Karaboyas, Angelo, Antlanger, Marlies, Saran, Rajiv, Wizemann, Volker, Chazot, Charles, Rayner, Hugh, Hörl, Walter H, Pisoni, Ronald L, Robinson, Bruce M, Sunder-Plassmann, Gere, Moissl, Ulrich, Kotanko, Peter, Levin, Nathan W, Säemann, Marcus D, Kalantar-Zadeh, Kamyar, Port, Friedrich K, and Wabel, Peter

Subjects
Cardiovascular, Kidney Disease, Dielectric Spectroscopy, Diet, Sodium-Restricted, Humans, Kidney Failure, Chronic, Plasma Volume, Renal Dialysis, Sodium, Sodium, Dietary, Water-Electrolyte Imbalance, Weight Gain, Hemodialysis, Fluid/electrolytes, Epidemiology, Volume overload, Interdialytic weight gain, Outcomes, additional, Clinical Sciences, Urology & Nephrology
Abstract

Predialysis volume overload is the sum of interdialytic weight gain (IDWG) and residual postdialysis volume overload. It results mostly from failure to achieve an adequate volume status at the end of the dialysis session. Recent developments in bioimpedance spectroscopy and possibly relative plasma volume monitoring permit noninvasive volume status assessment in hemodialysis patients. A large proportion of patients have previously been shown to be chronically volume overloaded predialysis (defined as >15% above 'normal' extracellular fluid volume, equivalent to >2.5 liters on average), and to exhibit a more than twofold increased mortality risk. By contrast, the magnitude of the mortality risk associated with IDWG is much smaller and only evident with very large weight gains. Here we review the available evidence on volume overload and IDWG, and question the use of IDWG as an indicator of 'nonadherence' by describing its association with postdialysis volume depletion. We also demonstrate the relationship between IDWG, volume overload and predialysis serum sodium concentration, and comment on salt intake. Discriminating between volume overload and IDWG will likely lead to a more appropriate management of fluid withdrawal during dialysis. Consensually, the present authors agree that this discrimination should be among the primary goals for dialysis caretakers today. In consequence, we recommend objective measures of volume status beyond mere evaluations of IDWG.

Published
2013

37. Patterns of Erythropoiesis-Stimulating Agent Use in European Hemodialysis Patients: The Dialysis Outcomes and Practice Patterns Study

Author

Fuller, Douglas S., Robinson, Bruce M., Locatelli, Francesco, and Pisoni, Ronald L.

Abstract

Background:Clinicians providing dialysis care have numerous erythropoiesis-stimulating agents (ESAs) available for treating anemia. We sought to provide a contemporary description of ESA types used in hemodialysis (HD) settings in nine European countries. Methods:Our study uses Dialysis Outcomes and Practice Patterns Study phase 5 (2012–2015) data from nine European countries (Belgium, France, ­Germany, Italy, Russia, Spain, Sweden, Turkey, and the United Kingdom). A total of 164 facilities and 3,281 patients contributed cross-sectional data. ESA types captured included short-acting epoetins (e.g., epoetin alfa, beta, etc., including biosimilars), darbepoetin alfa, and continuous erythropoietin receptor agonist (CERA; methoxy polyethylene glycol-epoetin beta). Results:We observed broad variability across countries in prescription of ESA types: prescription of epoetin alfa or epoetin beta ranged from 22% (France) to 78% (Russia), darbepoetin alfa prescription ranged from 13% (Russia) to 53% (UK), and CERA prescription ranged from <3% (Sweden) to 26% (France). Prescription of different ESA types varied substantially within some European countries from 2012–2015 but not across all countries in aggregate. Number of ESA types prescribed by a facility varied from 1, 2, 3, or 4 different ESA types in 32, 40, 21, and 8% of facilities, respectively. No differences were seen in the unadjusted distributions of achieved hemoglobin values by ESA type. Conclusion:A variety of short- and long-acting ESAs are commonly used in European HD facilities to maintain hemoglobin at remarkably similar levels with each ESA type. The availability of numerous ESA options for managing anemia has allowed European providers to optimize anemia management according to the particular circumstances of each patient.

Published
2024
Full Text
View/download PDF

40. Active Vitamin D Use and Fractures in Hemodialysis Patients: Results from the International DOPPS.

Author

Komaba, Hirotaka, Zhao, Junhui, Karaboyas, Angelo, Yamamoto, Suguru, Dasgupta, Indranil, Hassan, Mohamed, Zuo, Li, Christensson, Anders, Combe, Christian, Robinson, Bruce M., and Fukagawa, Masafumi

Abstract

Active vitamin D is commonly used to control secondary hyperparathyroidism in dialysis patients, but it is unknown whether active vitamin D directly improves bone strength, independently of its ability to suppress parathyroid hormone (PTH). We analyzed the association between the prescription of active vitamin D and incidence of any fracture and hip fracture in 41,677 in‐center hemodialysis patients from 21 countries in phases 3 to 6 (2005 to 2018) of the Dialysis Outcomes and Practice Patterns Study (DOPPS). We used Cox regression, adjusted for PTH and other potential confounders, and used a per‐protocol approach to censor patients at treatment switch during follow‐up. We also used a facility preference approach to minimize confounding by indication. Overall, 55% of patients were prescribed active vitamin D at study enrollment. Event rates (per patient‐year) were 0.024 for any fracture and 0.010 for hip fracture. The adjusted hazard ratio (95% confidence interval) comparing patients prescribed versus not prescribed active vitamin D was 1.02 (0.90 to 1.17) for any fracture and 1.00 (0.81 to 1.23) for hip fracture. In the facility preference approach, there was no difference in fracture rate between facilities with higher versus lower active vitamin D prescriptions. Thus, our results do not suggest a PTH‐independent benefit of active vitamin D in fracture prevention and support the current KDIGO guideline suggesting the use of active vitamin D only in subjects with elevated or rising PTH. Further research is needed to determine the role of active vitamin D beyond PTH control. © 2023 American Society for Bone and Mineral Research (ASBMR). [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results